Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name FFF probe13  Probe Info 
Probe concentration Probe:200uM; negative probe:200uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
SILAC
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Chronic myeloid leukemia [ICD-11:2A20]
Model Name Human chronic myeloid leukemia cells (K562)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 348 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12639  1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) 20.0
 LDTP05341  2-oxoglutarate dehydrogenase complex component E1 (OGDH) 20.0
 LDTP04441  26S proteasome non-ATPase regulatory subunit 7 (PSMD7) 20.0
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 20.0
 LDTP17247  5'-nucleotidase domain-containing protein 1 (NT5DC1) 20.0
 LDTP11321  Acetyl-CoA acetyltransferase, cytosolic (ACAT2) 20.0
 LDTP05905  Acid ceramidase (ASAH1) 20.0
 LDTP10394  Adenosylhomocysteinase 3 (AHCYL2) 20.0
 LDTP11318  ADP-ribose pyrophosphatase, mitochondrial (NUDT9) 20.0
 LDTP03900  ADP-ribosylation factor-like protein 1 (ARL1) 20.0
 LDTP14075  AFG3-like protein 2 (AFG3L2) 20.0
 LDTP06618  ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) 20.0
 LDTP06147  ATP-dependent RNA helicase DHX8 (DHX8) 20.0
 LDTP10848  ATP-dependent zinc metalloprotease YME1L1 (YME1L1) 20.0
 LDTP00491  Aurora kinase A (AURKA) 20.0
 LDTP03692  Bifunctional epoxide hydrolase 2 (EPHX2) 20.0
 LDTP12163  Calcyclin-binding protein (CACYBP) 20.0
 LDTP04358  Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) 20.0
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 20.0
 LDTP02223  Cathepsin B (CTSB) 20.0
 LDTP02198  Cathepsin D (CTSD) 20.0
 LDTP12873  CDGSH iron-sulfur domain-containing protein 1 (CISD1) 20.0
 LDTP10331  Cilia- and flagella-associated protein 36 (CFAP36) 20.0
 LDTP00497  Cyclin-G-associated kinase (GAK) 20.0
 LDTP03753  Cystathionine beta-synthase (CBS) 20.0
 LDTP03189  Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) 20.0
 LDTP00697  Cytochrome b5 type B (CYB5B) 20.0
 LDTP11723  Cytosolic 5'-nucleotidase 3A (NT5C3A) 20.0
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 20.0
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 20.0
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 20.0
 LDTP01769  Dihydrofolate reductase (DHFR) 20.0
 LDTP13294  Dipeptidyl peptidase 2 (DPP7) 20.0
 LDTP13251  DNA dC->dU-editing enzyme APOBEC-3B (APOBEC3B) 20.0
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 20.0
 LDTP07218  E3 ubiquitin-protein ligase BRE1A (RNF20) 20.0
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 20.0
 LDTP12868  Endoplasmic reticulum aminopeptidase 1 (ERAP1) 20.0
 LDTP02534  Endoplasmic reticulum chaperone BiP (HSPA5) 20.0
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 20.0
 LDTP09063  Estradiol 17-beta-dehydrogenase 11 (HSD17B11) 20.0
 LDTP10188  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) 20.0
 LDTP08232  Glycerol-3-phosphate acyltransferase 4 (GPAT4) 20.0
 LDTP14019  HBS1-like protein (HBS1L) 20.0
 LDTP12233  Helicase MOV-10 (MOV10) 20.0
 LDTP07931  Heme A synthase COX15 (COX15) 20.0
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 20.0
 LDTP01759  Histone-lysine N-methyltransferase NSD2 (NSD2) 20.0
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 20.0
 LDTP13358  Leucyl-cystinyl aminopeptidase (LNPEP) 20.0
 LDTP09043  Lysine-specific histone demethylase 2 (KDM1B) 20.0
 LDTP02505  Lysosomal protective protein (CTSA) 20.0
 LDTP08512  Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCAT) 20.0
 LDTP04009  Methylenetetrahydrofolate reductase (NADPH) (MTHFR) 20.0
 LDTP09396  Minor histocompatibility antigen H13 (HM13) 20.0
 LDTP06810  Mitochondrial import inner membrane translocase subunit TIM50 (TIMM50) 20.0
 LDTP01004  Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B) 20.0
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 20.0
 LDTP02798  NAD(P)H dehydrogenase [quinone] 1 (NQO1) 20.0
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 20.0
 LDTP03433  NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (NDUFS1) 20.0
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 20.0
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 20.0
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 20.0
 LDTP10077  Patatin-like phospholipase domain-containing protein 2 (PNPLA2) 20.0
 LDTP06638  Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2) 20.0
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 20.0
 LDTP04303  Presenilin-1 (PSEN1) 20.0
 LDTP07003  Presequence protease, mitochondrial (PITRM1) 20.0
 LDTP13285  Probable ATP-dependent RNA helicase DDX20 (DDX20) 20.0
 LDTP06750  Prolyl 3-hydroxylase 1 (P3H1) 20.0
 LDTP02679  Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) 20.0
 LDTP03060  Proteasome subunit beta type-1 (PSMB1) 20.0
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 20.0
 LDTP03418  Proteasome subunit beta type-6 (PSMB6) 20.0
 LDTP00988  Protein O-GlcNAcase (OGA) 20.0
 LDTP02549  Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) 20.0
 LDTP03726  Replication factor C subunit 2 (RFC2) 20.0
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 20.0
 LDTP03592  Ribonucleoside-diphosphate reductase subunit M2 (RRM2) 20.0
 LDTP00597  Serine palmitoyltransferase 1 (SPTLC1) 20.0
 LDTP04806  Sestrin-2 (SESN2) 20.0
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 20.0
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 20.0
 LDTP06142  Squalene monooxygenase (SQLE) 20.0
 LDTP10318  Ubiquitin thioesterase OTUB1 (OTUB1) 20.0
 LDTP12954  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) 20.0
 LDTP06104  Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8) 20.0
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 19.9
 LDTP05652  Aspartyl/asparaginyl beta-hydroxylase (ASPH) 19.2
 LDTP04248  Deoxyhypusine synthase (DHPS) 19.0
 LDTP02333  Glutathione S-transferase P (GSTP1) 18.2
 LDTP00717  Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPSS1) 18.1
 LDTP03552  Pyruvate kinase PKLR (PKLR) 18.1
 LDTP13408  Cell division cycle protein 23 homolog (CDC23) 17.8
 LDTP03511  Flavin reductase (NADPH) (BLVRB) 17.8
 LDTP11074  Tubulin alpha-1C chain (TUBA1C) 17.8
 LDTP11273  N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) 17.7
 LDTP04581  Holocytochrome c-type synthase (HCCS) 17.5
 LDTP11107  Serine/threonine-protein phosphatase CPPED1 (CPPED1) 17.5
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) 17.5
 LDTP04284  Proteasome subunit beta type-3 (PSMB3) 17.4
 LDTP10987  Tumor susceptibility gene 101 protein (TSG101) 17.3
 LDTP11904  Fructosamine-3-kinase (FN3K) 17.3
 LDTP03249  Plasma membrane calcium-transporting ATPase 4 (ATP2B4) 16.8
 LDTP07907  Tubulin alpha-1A chain (TUBA1A) 16.5
 LDTP05074  Tubulin alpha-1B chain (TUBA1B) 16.4
 LDTP01503  Mitofusin-2 (MFN2) 16.2
 LDTP01704  Phosphatidylserine lipase ABHD16A (ABHD16A) 16.1
 LDTP09364  Retinol dehydrogenase 11 (RDH11) 15.9
 LDTP04456  Ubiquitin carboxyl-terminal hydrolase 11 (USP11) 15.9
 LDTP19391  ATPase family AAA domain-containing protein 3C (ATAD3C) 15.8
 LDTP12810  Tubulin alpha-8 chain (TUBA8) 15.5
 LDTP11187  COP9 signalosome complex subunit 4 (COPS4) 15.5
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 15.4
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 15.2
 LDTP07154  ATPase family AAA domain-containing protein 3B (ATAD3B) 15.2
 LDTP04555  Serine/threonine-protein kinase PLK1 (PLK1) 14.9
 LDTP09925  COP9 signalosome complex subunit 5 (COPS5) 14.7
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 14.6
 LDTP05046  Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PPP2R2A) 14.4
 LDTP11225  Deoxyhypusine hydroxylase (DOHH) 14.3
 LDTP00186  Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) 14.3
 LDTP02984  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) 14.1
 LDTP08596  Mitochondrial Rho GTPase 2 (RHOT2) 14.1
 LDTP12851  UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1) 14.1
 LDTP02602  Histidine--tRNA ligase, cytoplasmic (HARS1) 14.0
 LDTP07227  Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) 13.7
 LDTP03145  Catechol O-methyltransferase (COMT) 13.6
 LDTP05478  Tyrosine-protein kinase BTK (BTK) 13.6
 LDTP11887  Tyrosine-protein phosphatase non-receptor type 23 (PTPN23) 13.5
 LDTP10500  Lymphokine-activated killer T-cell-originated protein kinase (PBK) 13.5
 LDTP03515  Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) 13.2
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 13.0
 LDTP00394  Chromodomain-helicase-DNA-binding protein 1 (CHD1) 12.9
 LDTP02837  Beta-galactosidase (GLB1) 12.7
 LDTP00836  ATPase GET3 (GET3) 12.6
 LDTP05255  Peptidyl-prolyl cis-trans isomerase FKBP3 (FKBP3) 12.2
 LDTP02362  Dihydrolipoyl dehydrogenase, mitochondrial (DLD) 12.1
 LDTP02279  Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) 12.0
 LDTP06384  Ribosomal protein S6 kinase alpha-1 (RPS6KA1) 11.9
 LDTP11051  ATP-dependent RNA helicase DDX50 (DDX50) 11.8
 LDTP06307  Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) 11.8
 LDTP04519  Kinesin-like protein KIF11 (KIF11) 11.8
 LDTP10286  Corrinoid adenosyltransferase MMAB (MMAB) 11.7
 LDTP05632  Mitochondrial-processing peptidase subunit alpha (PMPCA) 11.7
 LDTP02640  X-ray repair cross-complementing protein 6 (XRCC6) 11.6
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 11.6
 LDTP04032  Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2) 11.5
 LDTP00479  Histone acetyltransferase type B catalytic subunit (HAT1) 11.4
 LDTP02718  Glucosidase 2 subunit beta (PRKCSH) 11.4
 LDTP04531  Hexokinase-2 (HK2) 11.2
 LDTP04384  Cyclin-dependent kinase 9 (CDK9) 11.1
 LDTP03689  Serine hydroxymethyltransferase, mitochondrial (SHMT2) 11.1
 LDTP03610  Cytochrome b-c1 complex subunit 1, mitochondrial (UQCRC1) 11.0
 LDTP12608  Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) 11.0
 LDTP03891  Nicotinamide N-methyltransferase (NNMT) 10.9
 LDTP04374  Dynamin-2 (DNM2) 10.7
 LDTP01220  Mitochondrial-processing peptidase subunit beta (PMPCB) 10.7
 LDTP03417  Proteasome subunit beta type-4 (PSMB4) 10.7
 LDTP02260  Beta-glucuronidase (GUSB) 10.6
 LDTP04646  Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1) 10.6
 LDTP04400  Ras-related protein Rab-9A (RAB9A) 10.4
 LDTP09976  Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (ATP2A3) 10.3
 LDTP00294  26S proteasome non-ATPase regulatory subunit 14 (PSMD14) 10.3
 LDTP04004  Lysosomal Pro-X carboxypeptidase (PRCP) 10.2
 LDTP13787  RuvB-like 2 (RUVBL2) 10.2
 LDTP04183  Lanosterol synthase (LSS) 10.1
 LDTP05920  Calcium/calmodulin-dependent protein kinase type II subunit gamma (CAMK2G) 9.9
 LDTP04884  Proteasome subunit alpha type-6 (PSMA6) 9.9
 LDTP09899  Probable ATP-dependent RNA helicase DDX17 (DDX17) 9.8
 LDTP03198  Ferrochelatase, mitochondrial (FECH) 9.8
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) 9.7
 LDTP03813  Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (CPOX) 9.7
 LDTP00314  ATP-dependent RNA helicase DDX3X (DDX3X) 9.6
 LDTP01333  Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) 9.6
 LDTP02021  Ornithine aminotransferase, mitochondrial (OAT) 9.5
 LDTP00246  Eukaryotic translation initiation factor 3 subunit F (EIF3F) 9.4
 LDTP05480  Amidophosphoribosyltransferase (PPAT) 9.4
 LDTP04211  Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) 9.2
 LDTP02225  Heat shock protein HSP 90-alpha (HSP90AA1) 9.2
 LDTP01186  Vacuolar protein sorting-associated protein 4B (VPS4B) 9.1
 LDTP12610  Obg-like ATPase 1 (OLA1) 9.1
 LDTP01768  Glutamate dehydrogenase 1, mitochondrial (GLUD1) 9.0
 LDTP05372  Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) 9.0
 LDTP02188  Protein disulfide-isomerase (P4HB) 8.8
 LDTP00714  26S proteasome non-ATPase regulatory subunit 3 (PSMD3) 8.8
 LDTP01444  E3 UFM1-protein ligase 1 (UFL1) 8.8
 LDTP01770  NADH-cytochrome b5 reductase 3 (CYB5R3) 8.8
 LDTP06150  DNA replication licensing factor MCM6 (MCM6) 8.7
 LDTP13639  Vacuolar protein sorting-associated protein 4A (VPS4A) 8.7
 LDTP03842  Squalene synthase (FDFT1) 8.7
 LDTP03424  ATP-binding cassette sub-family D member 3 (ABCD3) 8.6
 LDTP04310  E3 SUMO-protein ligase RanBP2 (RANBP2) 8.6
 LDTP03817  Lon protease homolog, mitochondrial (LONP1) 8.6
 LDTP05971  Mannosyl-oligosaccharide glucosidase (MOGS) 8.6
 LDTP05192  ADP-ribosylation factor 1 (ARF1) 8.6
 LDTP04907  ADP-ribosylation factor 3 (ARF3) 8.6
 LDTP05193  ADP-ribosylation factor 5 (ARF5) 8.6
 LDTP07362  Atlastin-3 (ATL3) 8.5
 LDTP02935  Tyrosine-protein phosphatase non-receptor type 1 (PTPN1) 8.5
 LDTP02149  Cyclin-dependent kinase 1 (CDK1) 8.5
 LDTP02942  ADP-ribosylation factor 4 (ARF4) 8.5
 LDTP02283  Cytochrome c1, heme protein, mitochondrial (CYC1) 8.3
 LDTP07762  Hydroxysteroid dehydrogenase-like protein 2 (HSDL2) 8.3
 LDTP06199  Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D) 8.3
 LDTP10367  Serine/threonine-protein kinase greatwall (MASTL) 8.2
 LDTP01268  2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (GCAT) 8.2
 LDTP03445  Mitogen-activated protein kinase 1 (MAPK1) 8.2
 LDTP06612  2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (DECR1) 8.1
 LDTP04963  26S proteasome regulatory subunit 8 (PSMC5) 8.1
 LDTP12586  Phenylalanine--tRNA ligase beta subunit (FARSB) 8.0
 LDTP02150  ATP synthase subunit beta, mitochondrial (ATP5F1B) 8.0
 LDTP00890  S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) 8.0
 LDTP03938  N-alpha-acetyltransferase 10 (NAA10) 8.0
 LDTP06192  Neutral alpha-glucosidase AB (GANAB) 7.9
 LDTP08979  Prostaglandin reductase 2 (PTGR2) 7.8
 LDTP02924  Probable ATP-dependent RNA helicase DDX5 (DDX5) 7.7
 LDTP04196  26S proteasome non-ATPase regulatory subunit 8 (PSMD8) 7.5
 LDTP11297  Guanine nucleotide-binding protein-like 3 (GNL3) 7.5
 LDTP04471  Ribosomal protein S6 kinase alpha-3 (RPS6KA3) 7.5
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) 7.5
 LDTP02922  CTP synthase 1 (CTPS1) 7.4
 LDTP03682  DNA replication licensing factor MCM7 (MCM7) 7.4
 LDTP13126  Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2L) 7.4
 LDTP01634  Fatty acid CoA ligase Acsl3 (ACSL3) 7.3
 LDTP05128  Glutathione S-transferase omega-1 (GSTO1) 7.3
 LDTP12588  Isoleucine--tRNA ligase, mitochondrial (IARS2) 7.3
 LDTP14074  Ribosomal biogenesis protein LAS1L (LAS1L) 7.3
 LDTP02502  Thioredoxin (TXN) 7.3
 LDTP09962  Ubiquitin carboxyl-terminal hydrolase 7 (USP7) 7.2
 LDTP03419  Proteasome subunit beta type-5 (PSMB5) 7.2
 LDTP11841  ATP-dependent DNA/RNA helicase DHX36 (DHX36) 7.1
 LDTP13831  Phenylalanine--tRNA ligase alpha subunit (FARSA) 7.1
 LDTP09200  FAD synthase (FLAD1) 7.0
 LDTP05812  Ras GTPase-activating protein-binding protein 1 (G3BP1) 6.9
 LDTP13816  RuvB-like 1 (RUVBL1) 6.9
 LDTP10159  Pyrroline-5-carboxylate reductase 2 (PYCR2) 6.9
 LDTP08254  Ubiquitin carboxyl-terminal hydrolase 48 (USP48) 6.9
 LDTP00701  D-3-phosphoglycerate dehydrogenase (PHGDH) 6.8
 LDTP11494  Neurolysin, mitochondrial (NLN) 6.8
 LDTP04547  Nuclear pore complex protein Nup98-Nup96 (NUP98) 6.8
 LDTP06532  26S proteasome non-ATPase regulatory subunit 5 (PSMD5) 6.8
 LDTP02971  DNA ligase 1 (LIG1) 6.8
 LDTP03437  DNA polymerase delta catalytic subunit (POLD1) 6.8
 LDTP03770  Alpha-adducin (ADD1) 6.8
 LDTP04333  GMP synthase [glutamine-hydrolyzing] (GMPS) 6.7
 LDTP05244  Cyclin-dependent kinase 6 (CDK6) 6.7
 LDTP16274  Acyl-coenzyme A thioesterase 9, mitochondrial (ACOT9) 6.7
 LDTP04243  Fatty acid synthase (FASN) 6.6
 LDTP04061  26S proteasome regulatory subunit 6B (PSMC4) 6.6
 LDTP04878  Eukaryotic initiation factor 4A-I (EIF4A1) 6.5
 LDTP03523  Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PPP2R1B) 6.5
 LDTP02001  Catalase (CAT) 6.4
 LDTP04901  Ras-related protein Rab-14 (RAB14) 6.4
 LDTP03572  Succinate dehydrogenase flavoprotein subunit, mitochondrial (SDHA) 6.4
 LDTP10495  Ubiquitin carboxyl-terminal hydrolase 47 (USP47) 6.4
 LDTP10973  Thioredoxin, mitochondrial (TXN2) 6.4
 LDTP19851  Isochorismatase domain-containing protein 1 (ISOC1) 6.3
 LDTP07581  Aspartate--tRNA ligase, mitochondrial (DARS2) 6.3
 LDTP05312  Exosome complex component 10 (EXOSC10) 6.3
 LDTP15942  ATP-dependent RNA helicase DDX24 (DDX24) 6.3
 LDTP00273  Dynamin-1-like protein (DNM1L) 6.3
 LDTP00758  Thioredoxin-like protein 1 (TXNL1) 6.3
 LDTP06089  Eukaryotic initiation factor 4A-II (EIF4A2) 6.2
 LDTP03680  DNA replication licensing factor MCM4 (MCM4) 6.2
 LDTP00418  Protein arginine N-methyltransferase 5 (PRMT5) 6.2
 LDTP05841  Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PPP2R5C) 6.2
 LDTP06894  Acyl-coenzyme A synthetase ACSM3, mitochondrial (ACSM3) 6.1
 LDTP02385  Leukotriene A-4 hydrolase (LTA4H) 6.1
 LDTP03163  Sterol carrier protein 2 (SCP2) 6.1
 LDTP04286  DNA replication licensing factor MCM2 (MCM2) 6.1
 LDTP06432  Pachytene checkpoint protein 2 homolog (TRIP13) 6.1
 LDTP01238  NADH dehydrogenase iron-sulfur protein 3, mitochondrial (NDUFS3) 6.0
 LDTP02541  Heat shock cognate 71 kDa protein (HSPA8) 6.0
 LDTP03003  Interferon-induced, double-stranded RNA-activated protein kinase (EIF2AK2) 6.0
 LDTP03223  Small ribosomal subunit protein uS3 (RPS3) 6.0
 LDTP03156  Trifunctional purine biosynthetic protein adenosine-3 (GART) 6.0
 LDTP06338  Prostaglandin E synthase 3 (PTGES3) 5.9
 LDTP05588  RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) 5.9
 LDTP10997  Protein arginine N-methyltransferase 1 (PRMT1) 5.9
 LDTP02743  Insulin-degrading enzyme (IDE) 5.9
 LDTP03413  Proteasome subunit alpha type-5 (PSMA5) 5.9
 LDTP04317  NADH dehydrogenase flavoprotein 1, mitochondrial (NDUFV1) 5.9
 LDTP04712  Puromycin-sensitive aminopeptidase (NPEPPS) 5.8
 LDTP11733  Ras-related protein Rab-1B (RAB1B) 5.8
 LDTP04542  Thimet oligopeptidase (THOP1) 5.8
 LDTP02925  ATP-dependent 6-phosphofructokinase, liver type (PFKL) 5.8
 LDTP06190  Ubiquitin carboxyl-terminal hydrolase 10 (USP10) 5.7
 LDTP04987  26S proteasome regulatory subunit 10B (PSMC6) 5.7
 LDTP04074  Ubiquitin carboxyl-terminal hydrolase 5 (USP5) 5.7
 LDTP06535  Serine/threonine-protein kinase N1 (PKN1) 5.6
 LDTP03764  Myosin-9 (MYH9) 5.6
 LDTP01767  Aldehyde dehydrogenase 1A1 (ALDH1A1) 5.6
 LDTP03861  Eukaryotic initiation factor 4A-III (EIF4A3) 5.6
 LDTP00333  Serine/threonine-protein phosphatase 6 catalytic subunit (PPP6C) 5.6
 LDTP04163  Prolyl endopeptidase (PREP) 5.5
 LDTP12444  Xaa-Pro aminopeptidase 1 (XPNPEP1) 5.5
 LDTP02216  Beta-hexosaminidase subunit beta (HEXB) 5.5
 LDTP03765  Myosin-10 (MYH10) 5.5
 LDTP13031  Serine/threonine-protein kinase 26 (STK26) 5.5
 LDTP02329  3-ketoacyl-CoA thiolase, peroxisomal (ACAA1) 5.5
 LDTP04251  Elongation factor Tu, mitochondrial (TUFM) 5.5
 LDTP10386  ERO1-like protein alpha (ERO1A) 5.5
 LDTP05064  Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA) 5.5
 LDTP04998  Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PPP2CB) 5.5
 LDTP09067  Thioredoxin domain-containing protein 5 (TXNDC5) 5.5
 LDTP12597  BMP-2-inducible protein kinase (BMP2K) 5.4
 LDTP03975  Exosome RNA helicase MTR4 (MTREX) 5.4
 LDTP05052  S-phase kinase-associated protein 1 (SKP1) 5.4
 LDTP05136  DNA-dependent protein kinase catalytic subunit (PRKDC) 5.4
 LDTP12312  Ras-related protein Rab-18 (RAB18) 5.4
 LDTP08687  tRNA (uracil-5-)-methyltransferase homolog A (TRMT2A) 5.4
 LDTP03681  DNA replication licensing factor MCM5 (MCM5) 5.4
 LDTP05006  Ras-related protein Rab-1A (RAB1A) 5.4
 LDTP03965  Enoyl-CoA delta isomerase 1, mitochondrial (ECI1) 5.4
 LDTP06336  Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform (PPP2R5A) 5.4
 LDTP06279  Septin-2 (SEPTIN2) 5.4
 LDTP02642  X-ray repair cross-complementing protein 5 (XRCC5) 5.4
 LDTP12835  Large ribosomal subunit protein mL39 (MRPL39) 5.3
 LDTP13900  Glutathione S-transferase kappa 1 (GSTK1) 5.3
 LDTP11701  5'-3' exoribonuclease 2 (XRN2) 5.3
 LDTP03626  Peroxiredoxin-2 (PRDX2) 5.3
 LDTP01283  U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) 5.3
 LDTP03401  Multifunctional protein CAD (CAD) 5.3
 LDTP14311  SEC23-interacting protein (SEC23IP) 5.3
 LDTP05550  ATP-dependent RNA helicase A (DHX9) 5.2
 LDTP04690  Double-stranded RNA-specific adenosine deaminase (ADAR) 5.2
 LDTP00931  SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SMARCA5) 5.2
 LDTP11529  GTP-binding protein 4 (GTPBP4) 5.2
 LDTP13056  Leucine--tRNA ligase, cytoplasmic (LARS1) 5.2
 LDTP04096  Vesicle-fusing ATPase (NSF) 5.2
 LDTP01245  Enoyl-CoA delta isomerase 2 (ECI2) 5.1
 LDTP02693  Acylamino-acid-releasing enzyme (APEH) 5.1
 LDTP10954  3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) 5.1
 LDTP05071  Elongation factor 1-alpha 1 (EEF1A1) 5.1
 LDTP06067  Tubulin--tyrosine ligase-like protein 12 (TTLL12) 5.1
 LDTP02616  Creatine kinase B-type (CKB) 5.1
 LDTP10049  FAST kinase domain-containing protein 4 (TBRG4) 5.1
 LDTP03522  Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) 5.1
 LDTP10709  Pseudouridylate synthase 7 homolog (PUS7) 5.1
 LDTP02611  Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) 5.0
 LDTP03797  26S proteasome regulatory subunit 7 (PSMC2) 5.0
 LDTP02264  Asparagine synthetase [glutamine-hydrolyzing] (ASNS) 5.0
 LDTP10887  Synaptic vesicle membrane protein VAT-1 homolog (VAT1) 5.0
 LDTP04876  Actin, cytoplasmic 1 (ACTB) 5.0
 LDTP04440  Peroxisomal multifunctional enzyme type 2 (HSD17B4) 5.0
 LDTP00013  Ubiquitin-like modifier-activating enzyme 6 (UBA6) 5.0
Transporter and channel
Click to Show/Hide to Show 147 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11116  45 kDa calcium-binding protein (SDF4) 20.0
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 20.0
 LDTP01936  Apolipoprotein E (APOE) 20.0
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 20.0
 LDTP10036  BOS complex subunit NCLN (NCLN) 20.0
 LDTP06996  BOS complex subunit NOMO2 (NOMO2) 20.0
 LDTP01056  Coiled-coil domain-containing protein 22 (CCDC22) 20.0
 LDTP01301  Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (SLC25A12) 20.0
 LDTP13393  Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) 20.0
 LDTP12331  Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) 20.0
 LDTP00014  Extended synaptotagmin-2 (ESYT2) 20.0
 LDTP01366  Flotillin-1 (FLOT1) 20.0
 LDTP15064  G-protein coupled receptor-associated protein LMBRD2 (LMBRD2) 20.0
 LDTP04501  Importin subunit alpha-1 (KPNA2) 20.0
 LDTP00630  Importin-8 (IPO8) 20.0
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 20.0
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 20.0
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 20.0
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 20.0
 LDTP05900  Metaxin-1 (MTX1) 20.0
 LDTP11250  MICOS complex subunit MIC26 (APOO) 20.0
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 20.0
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 20.0
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 20.0
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 20.0
 LDTP00821  Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) 20.0
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 20.0
 LDTP14200  Mitochondrial ornithine transporter 1 (SLC25A15) 20.0
 LDTP12644  Mitochondrial potassium channel ATP-binding subunit (ABCB8) 20.0
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 20.0
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 20.0
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 20.0
 LDTP01295  Nuclear pore complex protein Nup155 (NUP155) 20.0
 LDTP11213  Nucleoporin NDC1 (NDC1) 20.0
 LDTP06331  Pericentriolar material 1 protein (PCM1) 20.0
 LDTP03905  Peroxisomal biogenesis factor 19 (PEX19) 20.0
 LDTP04213  Phosphatidylinositol transfer protein beta isoform (PITPNB) 20.0
 LDTP02215  Prosaposin (PSAP) 20.0
 LDTP04237  Protein ERGIC-53 (LMAN1) 20.0
 LDTP04707  Protein SEC13 homolog (SEC13) 20.0
 LDTP13164  Protein sel-1 homolog 1 (SEL1L) 20.0
 LDTP12207  Putative divalent cation/proton antiporter TMEM165 (TMEM165) 20.0
 LDTP14084  Sorting and assembly machinery component 50 homolog (SAMM50) 20.0
 LDTP18459  StAR-related lipid transfer protein 7, mitochondrial (STARD7) 20.0
 LDTP01454  SUN domain-containing protein 1 (SUN1) 20.0
 LDTP00592  Surfeit locus protein 4 (SURF4) 20.0
 LDTP00310  Syntenin-1 (SDCBP) 20.0
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 20.0
 LDTP13243  Translocation protein SEC63 homolog (SEC63) 20.0
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 20.0
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 20.0
 LDTP15948  Transmembrane protein 126A (TMEM126A) 20.0
 LDTP07477  Transmembrane protein 214 (TMEM214) 20.0
 LDTP15481  Transmembrane protein 87A (TMEM87A) 20.0
 LDTP07002  Transport and Golgi organization protein 1 homolog (MIA3) 20.0
 LDTP09949  Transportin-1 (TNPO1) 20.0
 LDTP00434  Transportin-2 (TNPO2) 20.0
 LDTP12533  Ubiquilin-4 (UBQLN4) 20.0
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 20.0
 LDTP05690  Vesicular integral-membrane protein VIP36 (LMAN2) 20.0
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 20.0
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 20.0
 LDTP00328  Importin subunit alpha-3 (KPNA4) 18.4
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 17.1
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 17.0
 LDTP04502  Importin subunit alpha-5 (KPNA1) 17.0
 LDTP06660  MICOS complex subunit MIC60 (IMMT) 16.5
 LDTP11531  Oxysterol-binding protein-related protein 8 (OSBPL8) 15.9
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 15.6
 LDTP00298  Importin subunit alpha-4 (KPNA3) 15.2
 LDTP13262  Signal recognition particle subunit SRP68 (SRP68) 15.1
 LDTP12704  Anoctamin-10 (ANO10) 14.5
 LDTP03870  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST) 14.2
 LDTP13953  Endophilin-B1 (SH3GLB1) 14.0
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 13.8
 LDTP03405  Calnexin (CANX) 13.6
 LDTP12090  Sideroflexin-1 (SFXN1) 13.6
 LDTP02608  ADP/ATP translocase 1 (SLC25A4) 13.3
 LDTP12142  Exportin-5 (XPO5) 12.7
 LDTP11310  Nuclear pore complex protein Nup85 (NUP85) 12.5
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 12.3
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 12.0
 LDTP01574  Importin-7 (IPO7) 11.6
 LDTP02087  ADP/ATP translocase 2 (SLC25A5) 11.6
 LDTP01043  Sorting nexin-2 (SNX2) 11.2
 LDTP08769  Nuclear pore complex protein Nup93 (NUP93) 11.1
 LDTP04393  Annexin A11 (ANXA11) 11.0
 LDTP02058  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) 10.9
 LDTP14174  Sorting nexin-5 (SNX5) 10.7
 LDTP04553  Tricarboxylate transport protein, mitochondrial (SLC25A1) 9.6
 LDTP01037  Catenin delta-1 (CTNND1) 9.6
 LDTP12510  Aladin (AAAS) 9.4
 LDTP01748  Mitochondrial import receptor subunit TOM40 homolog (TOMM40) 9.3
 LDTP03839  Nuclear pore glycoprotein p62 (NUP62) 9.2
 LDTP02010  Annexin A1 (ANXA1) 9.2
 LDTP04597  Methylosome subunit pICln (CLNS1A) 9.1
 LDTP09202  Nucleoporin Nup43 (NUP43) 9.0
 LDTP10885  Sortilin (SORT1) 8.5
 LDTP10069  Exocyst complex component 4 (EXOC4) 8.3
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) 8.3
 LDTP01969  Transferrin receptor protein 1 (TFRC) 8.0
 LDTP01601  Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) 8.0
 LDTP04800  Nuclear pore complex protein Nup107 (NUP107) 7.7
 LDTP09825  Nuclear pore complex protein Nup205 (NUP205) 7.7
 LDTP00810  Exportin-T (XPOT) 7.6
 LDTP09515  Importin-4 (IPO4) 7.6
 LDTP03777  Nuclear pore complex protein Nup214 (NUP214) 7.5
 LDTP13416  Stomatin-like protein 2, mitochondrial (STOML2) 7.3
 LDTP02262  Heat shock protein HSP 90-beta (HSP90AB1) 7.2
 LDTP09149  ATP-binding cassette sub-family F member 1 (ABCF1) 7.1
 LDTP10663  Importin-9 (IPO9) 7.1
 LDTP03327  ATP synthase subunit alpha, mitochondrial (ATP5F1A) 7.0
 LDTP02612  Nucleoprotein TPR (TPR) 7.0
 LDTP05934  Stromal interaction molecule 1 (STIM1) 6.9
 LDTP06462  Neutral amino acid transporter B(0) (SLC1A5) 6.8
 LDTP03717  Prohibitin 1 (PHB1) 6.8
 LDTP05510  Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP) 6.8
 LDTP12966  Vesicle-associated membrane protein-associated protein A (VAPA) 6.8
 LDTP03104  V-type proton ATPase subunit B, brain isoform (ATP6V1B2) 6.8
 LDTP18526  ATP-binding cassette sub-family F member 2 (ABCF2) 6.7
 LDTP05017  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (GNB1) 6.6
 LDTP02057  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) 6.6
 LDTP11161  Extended synaptotagmin-1 (ESYT1) 6.6
 LDTP03811  V-type proton ATPase subunit E 1 (ATP6V1E1) 6.5
 LDTP05020  Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (GNB2) 6.5
 LDTP00266  Importin-5 (IPO5) 6.5
 LDTP03664  Kinesin-1 heavy chain (KIF5B) 6.4
 LDTP11934  EH domain-containing protein 1 (EHD1) 6.3
 LDTP02247  Annexin A6 (ANXA6) 6.2
 LDTP04662  Exportin-2 (CSE1L) 6.1
 LDTP06549  Hsp90 co-chaperone Cdc37 (CDC37) 6.1
 LDTP14066  Hypoxia up-regulated protein 1 (HYOU1) 6.0
 LDTP10513  Exocyst complex component 2 (EXOC2) 5.8
 LDTP09502  Nuclear pore membrane glycoprotein 210 (NUP210) 5.7
 LDTP02544  Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) 5.7
 LDTP02547  Protein 4.1 (EPB41) 5.7
 LDTP03402  Calreticulin (CALR) 5.6
 LDTP11877  Golgi resident protein GCP60 (ACBD3) 5.5
 LDTP04953  14-3-3 protein gamma (YWHAG) 5.4
 LDTP10989  Copine-1 (CPNE1) 5.4
 LDTP13698  Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1) 5.1
 LDTP05625  AP-1 complex subunit beta-1 (AP1B1) 5.1
 LDTP02199  Annexin A2 (ANXA2) 5.1
 LDTP05273  Spectrin beta chain, non-erythrocytic 1 (SPTBN1) 5.1
 LDTP05384  Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) 5.1
 LDTP14509  ATP synthase subunit d, mitochondrial (ATP5PD) 5.0
 LDTP00501  Exportin-1 (XPO1) 5.0
Transcription factor
Click to Show/Hide to Show 12 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03212  Splicing factor, proline- and glutamine-rich (SFPQ) 14.0
 LDTP10891  DnaJ homolog subfamily C member 2 (DNAJC2) 13.4
 LDTP02870  Y-box-binding protein 3 (YBX3) 13.0
 LDTP04454  Signal transducer and activator of transcription 5B (STAT5B) 10.5
 LDTP03969  Signal transducer and activator of transcription 1-alpha/beta (STAT1) 9.6
 LDTP03971  Signal transducer and activator of transcription 5A (STAT5A) 9.4
 LDTP06341  Non-POU domain-containing octamer-binding protein (NONO) 7.7
 LDTP14809  CCAAT/enhancer-binding protein zeta (CEBPZ) 5.9
 LDTP10868  Cell division cycle 5-like protein (CDC5L) 5.5
 LDTP07940  eIF5-mimic protein 2 (BZW1) 5.3
 LDTP09932  SWI/SNF complex subunit SMARCC1 (SMARCC1) 5.2
 LDTP03903  Signal transducer and activator of transcription 3 (STAT3) 5.2
GPCR
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP14610  Golgi pH regulator B (GPR89B) 20.0
Other
Click to Show/Hide to Show 306 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP08364  Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) 20.0
 LDTP08682  Ankyrin repeat domain-containing protein 13A (ANKRD13A) 20.0
 LDTP06332  BOS complex subunit NOMO1 (NOMO1) 20.0
 LDTP05081  BOS complex subunit NOMO3 (NOMO3) 20.0
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 20.0
 LDTP05719  Cleavage stimulation factor subunit 3 (CSTF3) 20.0
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 20.0
 LDTP06515  Coiled-coil domain-containing protein 6 (CCDC6) 20.0
 LDTP09652  Cytoskeleton-associated protein 2 (CKAP2) 20.0
 LDTP04947  DDB1- and CUL4-associated factor 7 (DCAF7) 20.0
 LDTP04356  Emerin (EMD) 20.0
 LDTP13813  Eukaryotic translation initiation factor 3 subunit L (EIF3L) 20.0
 LDTP04652  Eukaryotic translation initiation factor 5 (EIF5) 20.0
 LDTP10078  Far upstream element-binding protein 1 (FUBP1) 20.0
 LDTP09938  Far upstream element-binding protein 2 (KHSRP) 20.0
 LDTP05501  Fragile X messenger ribonucleoprotein 1 (FMR1) 20.0
 LDTP07318  HAUS augmin-like complex subunit 3 (HAUS3) 20.0
 LDTP00500  Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) 20.0
 LDTP03614  Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) 20.0
 LDTP11238  Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) 20.0
 LDTP17065  Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) 20.0
 LDTP09820  La-related protein 4B (LARP4B) 20.0
 LDTP09619  Limb region 1 protein homolog (LMBR1) 20.0
 LDTP12764  MICOS complex subunit MIC19 (CHCHD3) 20.0
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 20.0
 LDTP13630  Neudesin (NENF) 20.0
 LDTP05375  Nucleobindin-1 (NUCB1) 20.0
 LDTP05160  Nucleobindin-2 (NUCB2) 20.0
 LDTP04684  Nucleosome assembly protein 1-like 1 (NAP1L1) 20.0
 LDTP10965  Nucleosome assembly protein 1-like 4 (NAP1L4) 20.0
 LDTP10889  Perilipin-2 (PLIN2) 20.0
 LDTP11825  Phosducin-like protein 3 (PDCL3) 20.0
 LDTP14017  Plakophilin-3 (PKP3) 20.0
 LDTP04935  Prefoldin subunit 3 (VBP1) 20.0
 LDTP02218  Profilin-1 (PFN1) 20.0
 LDTP11176  Protein canopy homolog 3 (CNPY3) 20.0
 LDTP01711  Protein ecdysoneless homolog (ECD) 20.0
 LDTP10056  Protein FAM162A (FAM162A) 20.0
 LDTP05734  Protein flightless-1 homolog (FLII) 20.0
 LDTP09116  Protein LSM14 homolog A (LSM14A) 20.0
 LDTP11350  Protein LSM14 homolog B (LSM14B) 20.0
 LDTP04199  Protein PRRC2A (PRRC2A) 20.0
 LDTP08130  Rab9 effector protein with kelch motifs (RABEPK) 20.0
 LDTP07476  RAD50-interacting protein 1 (RINT1) 20.0
 LDTP06097  Reticulocalbin-2 (RCN2) 20.0
 LDTP01522  Reticulon-3 (RTN3) 20.0
 LDTP12412  Reticulon-4 (RTN4) 20.0
 LDTP05224  RNA-binding protein 10 (RBM10) 20.0
 LDTP10684  RNA-binding protein 14 (RBM14) 20.0
 LDTP05318  RNA-binding protein EWS (EWSR1) 20.0
 LDTP03775  RNA-binding protein FUS (FUS) 20.0
 LDTP04396  RNA-binding protein FXR2 (FXR2) 20.0
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 20.0
 LDTP06684  Sister chromatid cohesion protein PDS5 homolog A (PDS5A) 20.0
 LDTP05930  SNW domain-containing protein 1 (SNW1) 20.0
 LDTP10214  Splicing factor ESS-2 homolog (ESS2) 20.0
 LDTP09563  Stromal membrane-associated protein 2 (SMAP2) 20.0
 LDTP00986  Syntaxin-10 (STX10) 20.0
 LDTP13086  Syntaxin-18 (STX18) 20.0
 LDTP09881  TATA-binding protein-associated factor 2N (TAF15) 20.0
 LDTP07368  Tetratricopeptide repeat protein 19, mitochondrial (TTC19) 20.0
 LDTP19372  Tetratricopeptide repeat protein 38 (TTC38) 20.0
 LDTP19963  TraB domain-containing protein (TRABD) 20.0
 LDTP16285  Transducin beta-like protein 2 (TBL2) 20.0
 LDTP18272  Transmembrane protein 209 (TMEM209) 20.0
 LDTP12830  U3 small nucleolar RNA-associated protein 6 homolog (UTP6) 20.0
 LDTP13626  Ubiquilin-1 (UBQLN1) 20.0
 LDTP13273  Ubiquilin-2 (UBQLN2) 20.0
 LDTP02297  Vimentin (VIM) 20.0
 LDTP07496  Zinc finger CCHC domain-containing protein 8 (ZCCHC8) 20.0
 LDTP03182  Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) 19.6
 LDTP04395  RNA-binding protein FXR1 (FXR1) 19.4
 LDTP04094  Large proline-rich protein BAG6 (BAG6) 18.7
 LDTP00991  Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) 18.6
 LDTP06391  Protein transport protein Sec23B (SEC23B) 18.6
 LDTP02053  Heat shock protein beta-1 (HSPB1) 18.5
 LDTP01600  BAG family molecular chaperone regulator 4 (BAG4) 18.3
 LDTP05400  Lamin-B2 (LMNB2) 18.2
 LDTP07888  Protein unc-13 homolog D (UNC13D) 17.9
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 17.6
 LDTP09851  Protein TFG (TFG) 17.4
 LDTP02205  Tubulin beta chain (TUBB) 16.8
 LDTP02037  Tubulin beta-4A chain (TUBB4A) 16.6
 LDTP00756  Heterogeneous nuclear ribonucleoprotein R (HNRNPR) 16.5
 LDTP01259  Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PRKRA) 16.5
 LDTP03841  Hippocalcin-like protein 1 (HPCAL1) 16.5
 LDTP05904  Tubulin beta-3 chain (TUBB3) 16.4
 LDTP13591  A-kinase anchor protein 8-like (AKAP8L) 16.4
 LDTP06378  Disks large-associated protein 5 (DLGAP5) 16.2
 LDTP10408  Far upstream element-binding protein 3 (FUBP3) 16.2
 LDTP13019  Vacuolar protein sorting-associated protein 18 homolog (VPS18) 16.2
 LDTP05076  Tubulin beta-4B chain (TUBB4B) 16.0
 LDTP09793  Small ribosomal subunit protein mS27 (MRPS27) 15.7
 LDTP11277  Tubulin beta-2B chain (TUBB2B) 15.7
 LDTP13430  Protein TASOR (TASOR) 15.3
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 15.3
 LDTP08224  Protein LYRIC (MTDH) 15.2
 LDTP12642  CYFIP-related Rac1 interactor B (CYRIB) 15.0
 LDTP10454  CDK5 regulatory subunit-associated protein 3 (CDK5RAP3) 15.0
 LDTP04495  Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) 14.9
 LDTP10097  Vacuolar protein sorting-associated protein 33A (VPS33A) 14.8
 LDTP08238  Kinectin (KTN1) 14.8
 LDTP05922  Dynactin subunit 2 (DCTN2) 14.8
 LDTP16116  BSD domain-containing protein 1 (BSDC1) 14.7
 LDTP05668  G-rich sequence factor 1 (GRSF1) 14.7
 LDTP11682  Polyadenylate-binding protein-interacting protein 1 (PAIP1) 14.5
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 14.5
 LDTP14172  Sorting nexin-9 (SNX9) 14.4
 LDTP04714  Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) 14.3
 LDTP04729  Ribosomal RNA processing protein 1 homolog A (RRP1) 14.3
 LDTP11324  RNA-binding protein 4 (RBM4) 14.1
 LDTP01285  TIP41-like protein (TIPRL) 14.0
 LDTP05768  Heterogeneous nuclear ribonucleoprotein A0 (HNRNPA0) 14.0
 LDTP03425  Tropomodulin-1 (TMOD1) 14.0
 LDTP03850  RNA-binding motif protein, X chromosome (RBMX) 13.9
 LDTP11233  Tubulin beta-6 chain (TUBB6) 13.5
 LDTP00887  Calumenin (CALU) 13.5
 LDTP18309  Protein HGH1 homolog (HGH1) 13.5
 LDTP05800  Serine/arginine-rich splicing factor 9 (SRSF9) 13.4
 LDTP02734  Endoplasmin (HSP90B1) 13.2
 LDTP06413  Microtubule-associated protein RP/EB family member 2 (MAPRE2) 13.1
 LDTP06032  Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) 13.1
 LDTP04241  Nuclear autoantigenic sperm protein (NASP) 13.1
 LDTP08793  Armadillo repeat-containing protein 10 (ARMC10) 12.9
 LDTP06060  Ubiquitin-associated protein 2-like (UBAP2L) 12.8
 LDTP09353  Guanine nucleotide exchange factor for Rab-3A (RAB3IL1) 12.8
 LDTP00236  Transcription elongation factor SPT5 (SUPT5H) 12.5
 LDTP11398  Serrate RNA effector molecule homolog (SRRT) 12.4
 LDTP11597  182 kDa tankyrase-1-binding protein (TNKS1BP1) 12.0
 LDTP04092  Crk-like protein (CRKL) 11.6
 LDTP15907  Hemogen (HEMGN) 11.5
 LDTP05525  KH domain-containing, RNA-binding, signal transduction-associated protein 1 (KHDRBS1) 11.4
 LDTP06121  Caprin-1 (CAPRIN1) 11.1
 LDTP00880  A-kinase anchor protein 8 (AKAP8) 11.1
 LDTP02227  Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) 11.1
 LDTP10847  Protein Niban 2 (NIBAN2) 11.1
 LDTP06390  Protein transport protein Sec23A (SEC23A) 11.1
 LDTP01933  Spectrin alpha chain, erythrocytic 1 (SPTA1) 10.8
 LDTP10271  DAZ-associated protein 1 (DAZAP1) 10.7
 LDTP04514  Heterogeneous nuclear ribonucleoprotein F (HNRNPF) 10.7
 LDTP15947  Mitochondrial fission regulator 1-like (MTFR1L) 10.6
 LDTP11643  Superkiller complex protein 8 (SKIC8) 10.6
 LDTP10700  KH domain-containing RNA-binding protein QKI (QKI) 10.5
 LDTP00223  26S proteasome non-ATPase regulatory subunit 11 (PSMD11) 10.4
 LDTP03352  Splicing factor U2AF 65 kDa subunit (U2AF2) 10.4
 LDTP11164  Ubiquitin-associated domain-containing protein 1 (UBAC1) 10.3
 LDTP03030  Annexin A7 (ANXA7) 10.2
 LDTP10185  FAS-associated factor 2 (FAF2) 10.2
 LDTP02364  Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) 10.2
 LDTP14272  Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) 10.2
 LDTP00620  Eukaryotic translation initiation factor 3 subunit H (EIF3H) 10.2
 LDTP12677  DnaJ homolog subfamily C member 11 (DNAJC11) 10.1
 LDTP00648  Melanoma-associated antigen B2 (MAGEB2) 10.1
 LDTP00376  Coatomer subunit epsilon (COPE) 10.0
 LDTP13467  RNA-binding protein Raly (RALY) 9.9
 LDTP05035  Growth factor receptor-bound protein 2 (GRB2) 9.9
 LDTP04425  Translocon-associated protein subunit delta (SSR4) 9.7
 LDTP11159  Gamma-tubulin complex component 2 (TUBGCP2) 9.7
 LDTP09950  Rho guanine nucleotide exchange factor 2 (ARHGEF2) 9.6
 LDTP08387  Dynein axonemal assembly factor 5 (DNAAF5) 9.5
 LDTP01319  Eukaryotic translation initiation factor 3 subunit G (EIF3G) 9.5
 LDTP09655  Ataxin-2-like protein (ATXN2L) 9.4
 LDTP01206  Vesicle-trafficking protein SEC22b (SEC22B) 9.2
 LDTP06385  Scaffold attachment factor B1 (SAFB) 9.2
 LDTP06054  Scaffold attachment factor B2 (SAFB2) 9.2
 LDTP02595  Polyadenylate-binding protein 1 (PABPC1) 9.2
 LDTP05437  Single-stranded DNA-binding protein, mitochondrial (SSBP1) 9.0
 LDTP09870  Signal transducing adapter molecule 1 (STAM) 9.0
 LDTP13309  Prefoldin subunit 2 (PFDN2) 9.0
 LDTP07903  La-related protein 4 (LARP4) 8.9
 LDTP03967  Lamina-associated polypeptide 2, isoform alpha (TMPO) 8.9
 LDTP13109  Melanoma-associated antigen C2 (MAGEC2) 8.9
 LDTP10873  Prefoldin subunit 5 (PFDN5) 8.9
 LDTP06096  Flotillin-2 (FLOT2) 8.9
 LDTP06444  Microtubule-associated protein RP/EB family member 1 (MAPRE1) 8.8
 LDTP09580  Programmed cell death 6-interacting protein (PDCD6IP) 8.8
 LDTP03606  DnaJ homolog subfamily A member 1 (DNAJA1) 8.8
 LDTP04917  Proteasome activator complex subunit 3 (PSME3) 8.7
 LDTP00272  Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) 8.7
 LDTP06450  ELAV-like protein 1 (ELAVL1) 8.6
 LDTP02631  Alpha-actinin-1 (ACTN1) 8.6
 LDTP01677  Double-stranded RNA-binding protein Staufen homolog 1 (STAU1) 8.6
 LDTP00843  Alpha-actinin-4 (ACTN4) 8.5
 LDTP05821  Polyadenylate-binding protein 4 (PABPC4) 8.5
 LDTP14105  YTH domain-containing family protein 2 (YTHDF2) 8.5
 LDTP01073  DnaJ homolog subfamily A member 2 (DNAJA2) 8.5
 LDTP03065  Lamin-B1 (LMNB1) 8.4
 LDTP13091  Ataxin-10 (ATXN10) 8.4
 LDTP03612  Bifunctional purine biosynthesis protein ATIC (ATIC) 8.4
 LDTP01432  Mitochondrial import receptor subunit TOM70 (TOMM70) 8.4
 LDTP04952  Heterogeneous nuclear ribonucleoprotein K (HNRNPK) 8.3
 LDTP10947  Ataxin-2 (ATXN2) 8.3
 LDTP11019  Endophilin-A2 (SH3GL1) 8.3
 LDTP12453  Something about silencing protein 10 (UTP3) 8.3
 LDTP05068  Tropomyosin alpha-4 chain (TPM4) 8.2
 LDTP11911  Golgi phosphoprotein 3 (GOLPH3) 8.2
 LDTP02128  Calbindin (CALB1) 8.1
 LDTP13657  Melanoma-associated antigen D2 (MAGED2) 8.1
 LDTP10071  Protein mago nashi homolog 2 (MAGOHB) 8.0
 LDTP02101  Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) 8.0
 LDTP04718  Eukaryotic translation initiation factor 3 subunit B (EIF3B) 8.0
 LDTP03325  DnaJ homolog subfamily B member 1 (DNAJB1) 8.0
 LDTP11197  Mini-chromosome maintenance complex-binding protein (MCMBP) 7.9
 LDTP04853  Eukaryotic translation initiation factor 3 subunit E (EIF3E) 7.9
 LDTP03982  Epidermal growth factor receptor substrate 15 (EPS15) 7.8
 LDTP15727  Protein LTV1 homolog (LTV1) 7.8
 LDTP06082  Dynactin subunit 1 (DCTN1) 7.8
 LDTP13519  Proteasome activator complex subunit 2 (PSME2) 7.8
 LDTP05233  55 kDa erythrocyte membrane protein (MPP1) 7.8
 LDTP10282  DnaJ homolog subfamily A member 3, mitochondrial (DNAJA3) 7.7
 LDTP05767  TAR DNA-binding protein 43 (TARDBP) 7.7
 LDTP04500  Heterogeneous nuclear ribonucleoprotein M (HNRNPM) 7.7
 LDTP10924  Prohibitin-2 (PHB2) 7.7
 LDTP10062  Synapse-associated protein 1 (SYAP1) 7.6
 LDTP07495  Caveolae-associated protein 1 (CAVIN1) 7.5
 LDTP04028  DNA mismatch repair protein Msh2 (MSH2) 7.4
 LDTP04201  T-complex protein 1 subunit epsilon (CCT5) 7.4
 LDTP08058  Mitochondrial antiviral-signaling protein (MAVS) 7.4
 LDTP03151  Oxysterol-binding protein 1 (OSBP) 7.4
 LDTP14228  Transforming acidic coiled-coil-containing protein 3 (TACC3) 7.4
 LDTP05689  Interleukin enhancer-binding factor 3 (ILF3) 7.3
 LDTP18494  Tropomodulin-3 (TMOD3) 7.3
 LDTP06881  Programmed cell death protein 4 (PDCD4) 7.2
 LDTP06367  Poly(rC)-binding protein 2 (PCBP2) 7.2
 LDTP07947  Eukaryotic translation initiation factor 3 subunit M (EIF3M) 7.2
 LDTP12476  Translation initiation factor eIF2B subunit gamma (EIF2B3) 7.2
 LDTP06305  WD repeat-containing protein 43 (WDR43) 7.2
 LDTP03997  Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) 7.1
 LDTP01920  Hemoglobin subunit zeta (HBZ) 7.1
 LDTP04906  COP9 signalosome complex subunit 2 (COPS2) 7.1
 LDTP06366  Poly(rC)-binding protein 1 (PCBP1) 7.0
 LDTP13955  Calcium-binding protein 39 (CAB39) 6.9
 LDTP05697  Heat shock protein 75 kDa, mitochondrial (TRAP1) 6.8
 LDTP13507  BAG family molecular chaperone regulator 5 (BAG5) 6.8
 LDTP01669  Polypyrimidine tract-binding protein 3 (PTBP3) 6.8
 LDTP01756  Actin-like protein 6A (ACTL6A) 6.7
 LDTP05277  Protein SET (SET) 6.7
 LDTP07605  La-related protein 1 (LARP1) 6.7
 LDTP06562  Histone-binding protein RBBP7 (RBBP7) 6.6
 LDTP13701  Serine/threonine-protein phosphatase 6 regulatory subunit 1 (PPP6R1) 6.6
 LDTP06301  Eukaryotic translation initiation factor 4H (EIF4H) 6.6
 LDTP12590  SAM domain-containing protein SAMSN-1 (SAMSN1) 6.6
 LDTP05239  Vigilin (HDLBP) 6.6
 LDTP05421  Eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) 6.5
 LDTP13760  Structural maintenance of chromosomes protein 3 (SMC3) 6.5
 LDTP04518  DNA mismatch repair protein Msh6 (MSH6) 6.4
 LDTP04112  Microtubule-associated protein 1B (MAP1B) 6.4
 LDTP17640  RNA-binding protein 12B (RBM12B) 6.4
 LDTP06182  Ribosomal RNA processing protein 1 homolog B (RRP1B) 6.4
 LDTP09721  DnaJ homolog subfamily C member 9 (DNAJC9) 6.3
 LDTP01932  Prelamin-A/C (LMNA) 6.3
 LDTP02480  RNA-binding protein RO60 (RO60) 6.3
 LDTP12904  Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) 6.3
 LDTP10914  Translin-associated protein X (TSNAX) 6.3
 LDTP17214  Protein odr-4 homolog (ODR4) 6.2
 LDTP04027  Matrin-3 (MATR3) 6.2
 LDTP00934  C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9) 6.2
 LDTP05024  Large ribosomal subunit protein uL1 (RPL10A) 6.2
 LDTP02263  Signal recognition particle receptor subunit alpha (SRPRA) 6.1
 LDTP11287  Nucleolar complex protein 4 homolog (NOC4L) 6.1
 LDTP10285  Small ribosomal subunit protein mS39 (PTCD3) 6.1
 LDTP04355  Rab GDP dissociation inhibitor beta (GDI2) 6.1
 LDTP10815  Spermatid perinuclear RNA-binding protein (STRBP) 6.1
 LDTP01456  Pre-mRNA-processing factor 6 (PRPF6) 6.0
 LDTP04964  Small ribosomal subunit protein eS8 (RPS8) 6.0
 LDTP19505  Tetratricopeptide repeat protein 27 (TTC27) 6.0
 LDTP03619  Stress-induced-phosphoprotein 1 (STIP1) 5.9
 LDTP06268  Condensin complex subunit 2 (NCAPH) 5.9
 LDTP05082  Hemoglobin subunit gamma-1 (HBG1) 5.9
 LDTP05083  Hemoglobin subunit gamma-2 (HBG2) 5.9
 LDTP02697  cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A) 5.8
 LDTP06003  Bystin (BYSL) 5.8
 LDTP09615  Sec1 family domain-containing protein 1 (SCFD1) 5.8
 LDTP08018  Zinc finger CCCH-type antiviral protein 1 (ZC3HAV1) 5.8
 LDTP04570  Coatomer subunit beta (COPB1) 5.7
 LDTP06429  Splicing factor 1 (SF1) 5.7
 LDTP04117  Ras GTPase-activating-like protein IQGAP1 (IQGAP1) 5.7
 LDTP01251  Splicing factor 3B subunit 1 (SF3B1) 5.7
 LDTP00206  Syntaxin-binding protein 3 (STXBP3) 5.7
 LDTP05985  Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) 5.7
 LDTP14216  Coatomer subunit gamma-1 (COPG1) 5.7
 LDTP02884  Heat shock 70 kDa protein 6 (HSPA6) 5.6
 LDTP05677  Splicing factor 3A subunit 3 (SF3A3) 5.6
 LDTP08935  ADP-ribosylation factor GTPase-activating protein 2 (ARFGAP2) 5.6
 LDTP05259  Heterogeneous nuclear ribonucleoprotein U (HNRNPU) 5.6
 LDTP06330  Plectin (PLEC) 5.6
 LDTP04412  Small ribosomal subunit protein mS29 (DAP3) 5.5
 LDTP03574  Rab GDP dissociation inhibitor alpha (GDI1) 5.5
 LDTP11058  Glutamate-rich WD repeat-containing protein 1 (GRWD1) 5.5
 LDTP05113  T-complex protein 1 subunit beta (CCT2) 5.5
 LDTP06083  Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) 5.4
 LDTP13210  Leucine-rich repeat and WD repeat-containing protein 1 (LRWD1) 5.4
 LDTP03767  Coatomer subunit beta' (COPB2) 5.4
 LDTP11144  Endoplasmic reticulum resident protein 44 (ERP44) 5.4
 LDTP05855  Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2) 5.4
 LDTP06983  Serine/threonine-protein phosphatase 6 regulatory subunit 3 (PPP6R3) 5.3
 LDTP06543  DNA damage-binding protein 1 (DDB1) 5.3
 LDTP09626  Heterogeneous nuclear ribonucleoprotein L-like (HNRNPLL) 5.3
 LDTP01252  Cold shock domain-containing protein E1 (CSDE1) 5.2
 LDTP03694  Heat shock 70 kDa protein 1-like (HSPA1L) 5.2
 LDTP04647  Alpha-soluble NSF attachment protein (NAPA) 5.2
 LDTP05098  Eukaryotic translation initiation factor 4 gamma 2 (EIF4G2) 5.2
 LDTP07958  Cytoplasmic FMR1-interacting protein 1 (CYFIP1) 5.1
 LDTP06377  Pumilio homolog 3 (PUM3) 5.1
 LDTP09821  Stalled ribosome sensor GCN1 (GCN1) 5.1
 LDTP04249  T-complex protein 1 subunit gamma (CCT3) 5.1

References

1 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.