Details of the Target

General Information of Target

Target ID LDTP08130
Target Name Rab9 effector protein with kelch motifs (RABEPK)
Gene Name RABEPK
Gene ID 10244
Synonyms
RAB9P40; Rab9 effector protein with kelch motifs; 40 kDa Rab9 effector protein; p40
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MKQLPVLEPGDKPRKATWYTLTVPGDSPCARVGHSCSYLPPVGNAKRGKVFIVGGANPNR
SFSDVHTMDLGKHQWDLDTCKGLLPRYEHASFIPSCTPDRIWVFGGANQSGNRNCLQVLN
PETRTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGAQPVQDTKLHVFDANTLTW
SQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAP
AGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQHWTLLKFDTLLPPGRLDHSMCI
IPWPVTCASEKEDSNSLTLNHEAEKEDSADKVMSHSGDSHEESQTATLLCLVFGGMNTEG
EIYDDCIVTVVD
Target Bioclass
Other
Subcellular location
Cytoplasm
Function Rab9 effector required for endosome to trans-Golgi network (TGN) transport.
Uniprot ID
Q7Z6M1
Ensemble ID
ENST00000259460.12
HGNC ID
HGNC:16896

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
HSC4 SNV: p.L289I DBIA    Probe Info 
IGR37 SNV: p.P58L DBIA    Probe Info 
IGR39 SNV: p.P58L DBIA    Probe Info 
IGROV1 SNV: p.D224N DBIA    Probe Info 
JURKAT SNV: p.G10R; p.A329V .
MEWO SNV: p.A146P DBIA    Probe Info 

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 14 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
IPM
 Probe Info  		C36(0.00); C115(0.00); C243(0.00); C96(0.00)  LDD0241  [2]
AHL-Pu-1
 Probe Info  		C307(2.01)  LDD0170  [3]
HHS-475
 Probe Info  		Y87(1.03)  LDD0264  [4]
HHS-465
 Probe Info  		Y87(7.74)  LDD2237  [5]
DBIA
 Probe Info  		C29(1.16); C80(0.87)  LDD0078  [6]
4-Iodoacetamidophenylacetylene
 Probe Info  		C29(0.00); C115(0.00); C36(0.00)  LDD0038  [7]
IA-alkyne
 Probe Info  		C80(0.00); C29(0.00); C243(0.00); C115(0.00)  LDD0036  [7]
Lodoacetamide azide
 Probe Info  		C80(0.00); C29(0.00); C243(0.00); C115(0.00)  LDD0037  [7]
VSF
 Probe Info  		N.A.  LDD0007  [8]
Acrolein
 Probe Info  		C29(0.00); C222(0.00); C243(0.00); C96(0.00)  LDD0217  [9]
W1
 Probe Info  		N.A.  LDD0236  [2]
AOyne
 Probe Info  		12.80  LDD0443  [10]
NAIA_5
 Probe Info  		C80(0.00); C29(0.00); C243(0.00); C36(0.00)  LDD2223  [11]
PAL-AfBPP Probe
Click To Hide/Show 44 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C045
 Probe Info  		6.68  LDD1744  [12]
C085
 Probe Info  		14.22  LDD1777  [12]
C106
 Probe Info  		19.03  LDD1793  [12]
C107
 Probe Info  		9.92  LDD1794  [12]
C108
 Probe Info  		14.72  LDD1795  [12]
C131
 Probe Info  		5.39  LDD1813  [12]
C159
 Probe Info  		9.06  LDD1839  [12]
C160
 Probe Info  		14.42  LDD1840  [12]
C163
 Probe Info  		6.32  LDD1843  [12]
C204
 Probe Info  		9.99  LDD1879  [12]
C206
 Probe Info  		17.39  LDD1881  [12]
C208
 Probe Info  		6.45  LDD1883  [12]
C211
 Probe Info  		14.52  LDD1885  [12]
C212
 Probe Info  		5.17  LDD1886  [12]
C213
 Probe Info  		32.90  LDD1887  [12]
C215
 Probe Info  		6.11  LDD1889  [12]
C218
 Probe Info  		22.94  LDD1892  [12]
C219
 Probe Info  		7.26  LDD1893  [12]
C220
 Probe Info  		26.54  LDD1894  [12]
C222
 Probe Info  		7.94  LDD1896  [12]
C225
 Probe Info  		4.99  LDD1898  [12]
C226
 Probe Info  		8.82  LDD1899  [12]
C229
 Probe Info  		7.16  LDD1902  [12]
C231
 Probe Info  		16.68  LDD1904  [12]
C277
 Probe Info  		19.97  LDD1947  [12]
C296
 Probe Info  		11.79  LDD1966  [12]
C342
 Probe Info  		5.10  LDD2004  [12]
C343
 Probe Info  		17.88  LDD2005  [12]
C344
 Probe Info  		6.92  LDD2006  [12]
C356
 Probe Info  		9.71  LDD2017  [12]
C357
 Probe Info  		8.51  LDD2018  [12]
C360
 Probe Info  		5.86  LDD2021  [12]
C380
 Probe Info  		6.77  LDD2039  [12]
FFF probe11
 Probe Info  		20.00  LDD0471  [13]
FFF probe12
 Probe Info  		20.00  LDD0473  [13]
FFF probe13
 Probe Info  		20.00  LDD0475  [13]
FFF probe14
 Probe Info  		20.00  LDD0477  [13]
FFF probe15
 Probe Info  		20.00  LDD0478  [13]
FFF probe2
 Probe Info  		20.00  LDD0463  [13]
FFF probe6
 Probe Info  		9.66  LDD0467  [13]
FFF probe7
 Probe Info  		20.00  LDD0483  [13]
JN0003
 Probe Info  		14.93  LDD0469  [13]
VE-P
 Probe Info  		N.A.  LDD0396  [14]
OEA-DA
 Probe Info  		20.00  LDD0046  [15]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0025  4SU-RNA DM93 C307(2.01)  LDD0170  [3]
 LDCM0026  4SU-RNA+native RNA DM93 C307(2.12)  LDD0171  [3]
 LDCM0214  AC1 HCT 116 C115(0.71); C29(1.02); C299(0.68); C307(0.74)  LDD0531  [6]
 LDCM0215  AC10 HCT 116 C115(0.74); C29(0.68); C307(1.31)  LDD0532  [6]
 LDCM0216  AC100 HCT 116 C115(0.67); C29(0.81); C80(1.07)  LDD0533  [6]
 LDCM0217  AC101 HCT 116 C115(0.91); C29(0.64); C80(1.04)  LDD0534  [6]
 LDCM0218  AC102 HCT 116 C115(0.79); C29(0.79); C80(1.04)  LDD0535  [6]
 LDCM0219  AC103 HCT 116 C115(0.75); C29(1.09); C80(0.99)  LDD0536  [6]
 LDCM0220  AC104 HCT 116 C115(0.69); C29(1.14); C80(1.14)  LDD0537  [6]
 LDCM0221  AC105 HCT 116 C115(0.78); C29(0.84); C80(0.90)  LDD0538  [6]
 LDCM0222  AC106 HCT 116 C115(0.67); C29(0.90); C80(0.94)  LDD0539  [6]
 LDCM0223  AC107 HCT 116 C115(0.71); C29(0.84); C80(0.76)  LDD0540  [6]
 LDCM0224  AC108 HCT 116 C115(0.72); C29(0.63); C80(0.92)  LDD0541  [6]
 LDCM0225  AC109 HCT 116 C115(0.64); C29(0.93); C80(1.06)  LDD0542  [6]
 LDCM0226  AC11 HCT 116 C115(1.05); C29(1.04); C307(1.28)  LDD0543  [6]
 LDCM0227  AC110 HCT 116 C115(0.87); C29(1.09); C80(0.97)  LDD0544  [6]
 LDCM0228  AC111 HCT 116 C115(0.77); C29(2.77); C80(0.87)  LDD0545  [6]
 LDCM0229  AC112 HCT 116 C115(0.83); C29(0.74); C80(1.13)  LDD0546  [6]
 LDCM0230  AC113 HCT 116 C115(1.04); C29(1.06); C80(0.80)  LDD0547  [6]
 LDCM0231  AC114 HCT 116 C115(0.98); C29(0.94); C80(0.89)  LDD0548  [6]
 LDCM0232  AC115 HCT 116 C115(0.99); C29(0.97); C80(0.78)  LDD0549  [6]
 LDCM0233  AC116 HCT 116 C115(1.18); C29(1.12); C80(0.84)  LDD0550  [6]
 LDCM0234  AC117 HCT 116 C115(1.21); C29(0.90); C80(0.81)  LDD0551  [6]
 LDCM0235  AC118 HCT 116 C115(1.17); C29(0.98); C80(0.78)  LDD0552  [6]
 LDCM0236  AC119 HCT 116 C115(1.65); C29(1.13); C80(0.79)  LDD0553  [6]
 LDCM0237  AC12 HCT 116 C115(1.00); C29(0.64); C307(1.14)  LDD0554  [6]
 LDCM0238  AC120 HCT 116 C115(0.43); C29(1.48); C80(0.77)  LDD0555  [6]
 LDCM0239  AC121 HCT 116 C115(0.83); C29(1.15); C80(0.76)  LDD0556  [6]
 LDCM0240  AC122 HCT 116 C115(1.01); C29(0.97); C80(0.81)  LDD0557  [6]
 LDCM0241  AC123 HCT 116 C115(0.61); C29(1.37); C80(0.77)  LDD0558  [6]
 LDCM0242  AC124 HCT 116 C115(0.83); C29(1.13); C80(0.84)  LDD0559  [6]
 LDCM0243  AC125 HCT 116 C115(0.96); C29(1.06); C80(0.75)  LDD0560  [6]
 LDCM0244  AC126 HCT 116 C115(0.99); C29(1.00); C80(0.75)  LDD0561  [6]
 LDCM0245  AC127 HCT 116 C115(0.98); C29(0.94); C80(0.86)  LDD0562  [6]
 LDCM0246  AC128 HCT 116 C29(0.93)  LDD0563  [6]
 LDCM0247  AC129 HCT 116 C29(0.86)  LDD0564  [6]
 LDCM0249  AC130 HCT 116 C29(0.87)  LDD0566  [6]
 LDCM0250  AC131 HCT 116 C29(1.04)  LDD0567  [6]
 LDCM0251  AC132 HCT 116 C29(0.87)  LDD0568  [6]
 LDCM0252  AC133 HCT 116 C29(0.98)  LDD0569  [6]
 LDCM0253  AC134 HCT 116 C29(1.07)  LDD0570  [6]
 LDCM0254  AC135 HCT 116 C29(0.91)  LDD0571  [6]
 LDCM0255  AC136 HCT 116 C29(1.02)  LDD0572  [6]
 LDCM0256  AC137 HCT 116 C29(0.91)  LDD0573  [6]
 LDCM0257  AC138 HCT 116 C29(1.19)  LDD0574  [6]
 LDCM0258  AC139 HCT 116 C29(1.00)  LDD0575  [6]
 LDCM0259  AC14 HCT 116 C115(1.06); C29(0.81); C307(1.58)  LDD0576  [6]
 LDCM0260  AC140 HCT 116 C29(1.22)  LDD0577  [6]
 LDCM0261  AC141 HCT 116 C29(1.22)  LDD0578  [6]
 LDCM0262  AC142 HCT 116 C29(1.01)  LDD0579  [6]
 LDCM0263  AC143 HCT 116 C115(0.91)  LDD0580  [6]
 LDCM0264  AC144 HCT 116 C115(1.03)  LDD0581  [6]
 LDCM0265  AC145 HCT 116 C115(1.25)  LDD0582  [6]
 LDCM0266  AC146 HCT 116 C115(1.06)  LDD0583  [6]
 LDCM0267  AC147 HCT 116 C115(0.98)  LDD0584  [6]
 LDCM0268  AC148 HCT 116 C115(1.10)  LDD0585  [6]
 LDCM0269  AC149 HCT 116 C115(1.08)  LDD0586  [6]
 LDCM0270  AC15 HCT 116 C29(0.69); C115(1.06); C307(1.08)  LDD0587  [6]
 LDCM0271  AC150 HCT 116 C115(1.05)  LDD0588  [6]
 LDCM0272  AC151 HCT 116 C115(1.18)  LDD0589  [6]
 LDCM0273  AC152 HCT 116 C115(1.00)  LDD0590  [6]
 LDCM0274  AC153 HCT 116 C115(1.45)  LDD0591  [6]
 LDCM0621  AC154 HCT 116 C115(1.08)  LDD2158  [6]
 LDCM0622  AC155 HCT 116 C115(1.24)  LDD2159  [6]
 LDCM0623  AC156 HCT 116 C115(1.18)  LDD2160  [6]
 LDCM0624  AC157 HCT 116 C115(0.98)  LDD2161  [6]
 LDCM0276  AC17 HCT 116 C29(0.63); C80(0.90); C115(0.97)  LDD0593  [6]
 LDCM0277  AC18 HCT 116 C115(0.85); C29(0.90); C80(1.27)  LDD0594  [6]
 LDCM0278  AC19 HCT 116 C80(0.88); C29(0.94); C115(1.21)  LDD0595  [6]
 LDCM0279  AC2 HCT 116 C80(0.76); C307(0.92); C115(0.95); C29(1.00)  LDD0596  [6]
 LDCM0280  AC20 HCT 116 C80(0.89); C115(1.14); C29(1.32)  LDD0597  [6]
 LDCM0281  AC21 HCT 116 C29(0.87); C80(0.96); C115(1.14)  LDD0598  [6]
 LDCM0282  AC22 HCT 116 C29(0.77); C80(0.83); C115(1.07)  LDD0599  [6]
 LDCM0283  AC23 HCT 116 C29(0.73); C80(0.79); C115(1.24)  LDD0600  [6]
 LDCM0284  AC24 HCT 116 C80(0.87); C29(0.97); C115(1.04)  LDD0601  [6]
 LDCM0285  AC25 HCT 116 C115(0.93); C29(1.24)  LDD0602  [6]
 LDCM0286  AC26 HCT 116 C115(1.06); C29(1.12)  LDD0603  [6]
 LDCM0287  AC27 HCT 116 C115(0.94); C29(2.15)  LDD0604  [6]
 LDCM0288  AC28 HCT 116 C115(1.06); C29(1.25)  LDD0605  [6]
 LDCM0289  AC29 HCT 116 C115(1.14); C29(1.24)  LDD0606  [6]
 LDCM0290  AC3 HCT 116 C29(0.76); C307(0.81); C299(0.82); C80(0.89)  LDD0607  [6]
 LDCM0291  AC30 HCT 116 C115(1.14); C29(1.66)  LDD0608  [6]
 LDCM0292  AC31 HCT 116 C115(1.10); C29(2.10)  LDD0609  [6]
 LDCM0293  AC32 HCT 116 C115(1.20); C29(1.20)  LDD0610  [6]
 LDCM0294  AC33 HCT 116 C115(0.99); C29(1.33)  LDD0611  [6]
 LDCM0295  AC34 HCT 116 C115(0.68); C29(2.14)  LDD0612  [6]
 LDCM0296  AC35 HCT 116 C115(0.78); C29(1.21)  LDD0613  [6]
 LDCM0297  AC36 HCT 116 C115(0.86); C29(1.16)  LDD0614  [6]
 LDCM0298  AC37 HCT 116 C115(0.75); C29(0.83)  LDD0615  [6]
 LDCM0299  AC38 HCT 116 C115(0.90); C29(1.02)  LDD0616  [6]
 LDCM0300  AC39 HCT 116 C115(0.89); C29(0.91)  LDD0617  [6]
 LDCM0301  AC4 HCT 116 C29(0.75); C307(0.82); C80(0.89); C299(0.92)  LDD0618  [6]
 LDCM0302  AC40 HCT 116 C115(1.09); C29(1.13)  LDD0619  [6]
 LDCM0303  AC41 HCT 116 C115(0.74); C29(1.06)  LDD0620  [6]
 LDCM0304  AC42 HCT 116 C115(0.79); C29(1.11)  LDD0621  [6]
 LDCM0305  AC43 HCT 116 C115(0.61); C29(1.02)  LDD0622  [6]
 LDCM0306  AC44 HCT 116 C115(0.90); C29(1.32)  LDD0623  [6]
 LDCM0307  AC45 HCT 116 C115(0.65); C29(1.46)  LDD0624  [6]
 LDCM0308  AC46 HCT 116 C29(1.05)  LDD0625  [6]
 LDCM0309  AC47 HCT 116 C29(1.10)  LDD0626  [6]
 LDCM0310  AC48 HCT 116 C29(0.92)  LDD0627  [6]
 LDCM0311  AC49 HCT 116 C29(1.59)  LDD0628  [6]
 LDCM0312  AC5 HCT 116 C29(0.75); C307(0.75); C299(0.80); C80(0.85)  LDD0629  [6]
 LDCM0313  AC50 HCT 116 C29(1.13)  LDD0630  [6]
 LDCM0314  AC51 HCT 116 C29(0.84)  LDD0631  [6]
 LDCM0315  AC52 HCT 116 C29(0.92)  LDD0632  [6]
 LDCM0316  AC53 HCT 116 C29(1.41)  LDD0633  [6]
 LDCM0317  AC54 HCT 116 C29(1.27)  LDD0634  [6]
 LDCM0318  AC55 HCT 116 C29(1.46)  LDD0635  [6]
 LDCM0319  AC56 HCT 116 C29(2.14)  LDD0636  [6]
 LDCM0320  AC57 HCT 116 C115(0.97); C80(1.00); C29(1.08); C299(1.21)  LDD0637  [6]
 LDCM0321  AC58 HCT 116 C80(0.91); C115(0.92); C299(1.00); C307(1.00)  LDD0638  [6]
 LDCM0322  AC59 HCT 116 C115(0.87); C80(0.98); C29(1.34); C299(1.46)  LDD0639  [6]
 LDCM0323  AC6 HCT 116 C115(0.86); C307(1.11); C29(1.13)  LDD0640  [6]
 LDCM0324  AC60 HCT 116 C115(0.91); C80(1.10); C29(1.21); C299(1.21)  LDD0641  [6]
 LDCM0325  AC61 HCT 116 C29(0.94); C80(0.99); C115(1.12); C299(1.26)  LDD0642  [6]
 LDCM0326  AC62 HCT 116 C80(1.02); C115(1.07); C299(1.11); C307(1.11)  LDD0643  [6]
 LDCM0327  AC63 HCT 116 C115(0.94); C80(1.00); C299(1.15); C307(1.15)  LDD0644  [6]
 LDCM0328  AC64 HCT 116 C80(1.12); C299(1.13); C307(1.13); C115(1.16)  LDD0645  [6]
 LDCM0329  AC65 HCT 116 C115(0.93); C80(1.10); C29(1.31); C299(1.47)  LDD0646  [6]
 LDCM0330  AC66 HCT 116 C80(1.03); C115(1.07); C29(1.37); C299(1.53)  LDD0647  [6]
 LDCM0331  AC67 HCT 116 C115(1.04); C299(1.12); C307(1.12); C80(1.24)  LDD0648  [6]
 LDCM0332  AC68 HCT 116 C80(0.96); C115(0.97)  LDD0649  [6]
 LDCM0333  AC69 HCT 116 C115(0.82); C80(1.02)  LDD0650  [6]
 LDCM0334  AC7 HCT 116 C29(0.55); C115(0.91); C307(0.97)  LDD0651  [6]
 LDCM0335  AC70 HCT 116 C80(1.08); C115(1.71)  LDD0652  [6]
 LDCM0336  AC71 HCT 116 C115(1.00); C80(1.01)  LDD0653  [6]
 LDCM0337  AC72 HCT 116 C80(1.20); C115(1.34)  LDD0654  [6]
 LDCM0338  AC73 HCT 116 C80(1.13); C115(1.41)  LDD0655  [6]
 LDCM0339  AC74 HCT 116 C80(0.88); C115(1.13)  LDD0656  [6]
 LDCM0340  AC75 HCT 116 C115(1.18); C80(1.29)  LDD0657  [6]
 LDCM0341  AC76 HCT 116 C80(1.06); C115(1.10)  LDD0658  [6]
 LDCM0342  AC77 HCT 116 C115(0.85); C80(0.97)  LDD0659  [6]
 LDCM0343  AC78 HCT 116 C80(0.97); C115(1.00)  LDD0660  [6]
 LDCM0344  AC79 HCT 116 C80(1.10); C115(1.33)  LDD0661  [6]
 LDCM0345  AC8 HCT 116 C115(0.89); C29(1.03); C307(1.15)  LDD0662  [6]
 LDCM0346  AC80 HCT 116 C80(0.84); C115(1.28)  LDD0663  [6]
 LDCM0347  AC81 HCT 116 C80(1.07); C115(1.22)  LDD0664  [6]
 LDCM0348  AC82 HCT 116 C80(0.95); C115(1.36)  LDD0665  [6]
 LDCM0349  AC83 HCT 116 C115(1.09); C80(1.20); C29(1.82)  LDD0666  [6]
 LDCM0350  AC84 HCT 116 C115(1.06); C80(1.22); C29(1.52)  LDD0667  [6]
 LDCM0351  AC85 HCT 116 C115(0.93); C80(1.07); C29(1.43)  LDD0668  [6]
 LDCM0352  AC86 HCT 116 C80(1.02); C29(1.41); C115(1.41)  LDD0669  [6]
 LDCM0353  AC87 HCT 116 C115(0.91); C80(0.93); C29(1.36)  LDD0670  [6]
 LDCM0354  AC88 HCT 116 C80(1.07); C115(1.20); C29(1.36)  LDD0671  [6]
 LDCM0355  AC89 HCT 116 C80(1.04); C115(1.10); C29(1.44)  LDD0672  [6]
 LDCM0357  AC90 HCT 116 C80(1.02); C29(1.06); C115(1.20)  LDD0674  [6]
 LDCM0358  AC91 HCT 116 C80(1.21); C115(1.36); C29(1.99)  LDD0675  [6]
 LDCM0359  AC92 HCT 116 C80(1.18); C115(1.28); C29(1.73)  LDD0676  [6]
 LDCM0360  AC93 HCT 116 C115(0.97); C80(1.02); C29(1.29)  LDD0677  [6]
 LDCM0361  AC94 HCT 116 C80(1.08); C115(1.22); C29(1.45)  LDD0678  [6]
 LDCM0362  AC95 HCT 116 C80(0.97); C115(1.15); C29(1.21)  LDD0679  [6]
 LDCM0363  AC96 HCT 116 C80(1.07); C115(1.25); C29(1.57)  LDD0680  [6]
 LDCM0364  AC97 HCT 116 C80(1.13); C115(1.34); C29(1.68)  LDD0681  [6]
 LDCM0365  AC98 HCT 116 C29(0.77); C115(0.78); C80(1.12)  LDD0682  [6]
 LDCM0366  AC99 HCT 116 C29(0.62); C115(0.72); C80(0.85)  LDD0683  [6]
 LDCM0248  AKOS034007472 HCT 116 C115(1.13); C29(0.87); C307(1.26)  LDD0565  [6]
 LDCM0356  AKOS034007680 HCT 116 C29(0.61); C115(0.87); C307(1.25)  LDD0673  [6]
 LDCM0275  AKOS034007705 HCT 116 C115(0.81); C29(1.36); C307(1.38)  LDD0592  [6]
 LDCM0156  Aniline NCI-H1299 13.56  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C29(1.16); C80(0.87)  LDD0078  [6]
 LDCM0630  CCW28-3 231MFP C115(1.99)  LDD2214  [16]
 LDCM0108  Chloroacetamide HeLa C243(0.00); C222(0.00); C96(0.00)  LDD0222  [9]
 LDCM0367  CL1 HCT 116 C80(0.90); C299(0.93); C307(0.93); C29(1.14)  LDD0684  [6]
 LDCM0368  CL10 HCT 116 C299(1.10); C307(1.10); C29(1.19); C115(1.20)  LDD0685  [6]
 LDCM0369  CL100 HCT 116 C299(0.71); C80(0.73); C307(0.76); C115(0.99)  LDD0686  [6]
 LDCM0370  CL101 HCT 116 C29(0.87); C115(0.87); C307(2.26)  LDD0687  [6]
 LDCM0371  CL102 HCT 116 C29(0.65); C115(0.75); C307(1.71)  LDD0688  [6]
 LDCM0372  CL103 HCT 116 C29(0.69); C115(0.85); C307(1.56)  LDD0689  [6]
 LDCM0373  CL104 HCT 116 C29(0.63); C115(1.08); C307(1.80)  LDD0690  [6]
 LDCM0374  CL105 HCT 116 C29(0.63); C80(1.10); C115(1.26)  LDD0691  [6]
 LDCM0375  CL106 HCT 116 C29(0.63); C115(1.19); C80(1.33)  LDD0692  [6]
 LDCM0376  CL107 HCT 116 C29(0.75); C80(1.12); C115(1.52)  LDD0693  [6]
 LDCM0377  CL108 HCT 116 C29(0.59); C115(1.32); C80(1.40)  LDD0694  [6]
 LDCM0378  CL109 HCT 116 C29(0.59); C80(1.04); C115(1.15)  LDD0695  [6]
 LDCM0379  CL11 HCT 116 C299(0.81); C307(0.81); C115(1.02); C80(1.37)  LDD0696  [6]
 LDCM0380  CL110 HCT 116 C29(0.65); C80(0.99); C115(1.19)  LDD0697  [6]
 LDCM0381  CL111 HCT 116 C29(0.86); C80(0.91); C115(1.08)  LDD0698  [6]
 LDCM0382  CL112 HCT 116 C115(1.04); C29(1.18)  LDD0699  [6]
 LDCM0383  CL113 HCT 116 C115(0.89); C29(1.15)  LDD0700  [6]
 LDCM0384  CL114 HCT 116 C115(0.86); C29(1.07)  LDD0701  [6]
 LDCM0385  CL115 HCT 116 C115(0.90); C29(1.42)  LDD0702  [6]
 LDCM0386  CL116 HCT 116 C115(0.78); C29(1.14)  LDD0703  [6]
 LDCM0387  CL117 HCT 116 C115(0.68); C29(1.49)  LDD0704  [6]
 LDCM0388  CL118 HCT 116 C29(1.12); C115(1.35)  LDD0705  [6]
 LDCM0389  CL119 HCT 116 C115(0.80); C29(1.17)  LDD0706  [6]
 LDCM0390  CL12 HCT 116 C299(0.88); C307(0.88); C115(1.30); C80(1.46)  LDD0707  [6]
 LDCM0391  CL120 HCT 116 C115(0.82); C29(0.90)  LDD0708  [6]
 LDCM0392  CL121 HCT 116 C29(1.47)  LDD0709  [6]
 LDCM0393  CL122 HCT 116 C29(1.09)  LDD0710  [6]
 LDCM0394  CL123 HCT 116 C29(1.50)  LDD0711  [6]
 LDCM0395  CL124 HCT 116 C29(1.79)  LDD0712  [6]
 LDCM0396  CL125 HCT 116 C29(0.98); C299(1.00); C307(1.00); C80(1.02)  LDD0713  [6]
 LDCM0397  CL126 HCT 116 C115(0.83); C299(0.95); C307(0.95); C80(1.08)  LDD0714  [6]
 LDCM0398  CL127 HCT 116 C115(0.84); C299(0.94); C307(0.94); C80(1.13)  LDD0715  [6]
 LDCM0399  CL128 HCT 116 C115(0.99); C80(1.05); C29(1.08); C299(1.20)  LDD0716  [6]
 LDCM0400  CL13 HCT 116 C115(1.04); C299(1.15); C307(1.15); C29(1.31)  LDD0717  [6]
 LDCM0401  CL14 HCT 116 C299(0.63); C307(0.63); C80(1.12); C115(1.14)  LDD0718  [6]
 LDCM0402  CL15 HCT 116 C115(1.01); C29(1.04); C80(1.28); C299(1.44)  LDD0719  [6]
 LDCM0403  CL16 HCT 116 C115(1.08); C29(1.54); C299(1.66); C307(1.66)  LDD0720  [6]
 LDCM0404  CL17 HCT 116 C29(1.03); C80(1.06); C115(1.09); C299(1.45)  LDD0721  [6]
 LDCM0405  CL18 HCT 116 C80(0.95); C115(1.07); C299(1.72); C307(1.72)  LDD0722  [6]
 LDCM0406  CL19 HCT 116 C80(0.97); C115(1.03); C299(1.65); C307(1.65)  LDD0723  [6]
 LDCM0407  CL2 HCT 116 C299(0.51); C307(0.51); C80(1.01); C29(1.05)  LDD0724  [6]
 LDCM0408  CL20 HCT 116 C80(1.11); C115(1.46); C29(1.67); C299(1.84)  LDD0725  [6]
 LDCM0409  CL21 HCT 116 C80(0.93); C115(1.16); C29(1.57); C299(1.75)  LDD0726  [6]
 LDCM0410  CL22 HCT 116 C115(0.93); C80(1.03); C299(1.80); C307(1.80)  LDD0727  [6]
 LDCM0411  CL23 HCT 116 C115(0.97); C80(1.26); C299(1.92); C307(1.92)  LDD0728  [6]
 LDCM0412  CL24 HCT 116 C115(1.08); C29(1.59); C299(1.73); C307(1.73)  LDD0729  [6]
 LDCM0413  CL25 HCT 116 C115(0.87); C29(1.60); C299(1.81); C307(1.81)  LDD0730  [6]
 LDCM0414  CL26 HCT 116 C115(0.96); C29(1.57); C299(1.54); C307(1.54)  LDD0731  [6]
 LDCM0415  CL27 HCT 116 C115(1.20); C29(1.67); C299(1.70); C307(1.70)  LDD0732  [6]
 LDCM0416  CL28 HCT 116 C115(1.09); C29(2.46); C299(1.83); C307(1.83)  LDD0733  [6]
 LDCM0417  CL29 HCT 116 C115(1.19); C29(1.69); C299(1.88); C307(1.88)  LDD0734  [6]
 LDCM0418  CL3 HCT 116 C115(1.05); C29(1.28); C299(0.73); C307(0.73)  LDD0735  [6]
 LDCM0419  CL30 HCT 116 C115(0.93); C29(1.66); C299(1.52); C307(1.52)  LDD0736  [6]
 LDCM0420  CL31 HCT 116 C115(1.02); C29(0.97); C307(0.89); C80(0.95)  LDD0737  [6]
 LDCM0421  CL32 HCT 116 C115(0.99); C29(0.88); C307(0.81); C80(1.02)  LDD0738  [6]
 LDCM0422  CL33 HCT 116 C115(1.12); C29(0.95); C307(0.78); C80(1.13)  LDD0739  [6]
 LDCM0423  CL34 HCT 116 C115(1.17); C29(1.16); C307(1.17); C80(1.17)  LDD0740  [6]
 LDCM0424  CL35 HCT 116 C115(1.11); C29(1.70); C307(1.01); C80(1.12)  LDD0741  [6]
 LDCM0425  CL36 HCT 116 C115(0.93); C29(1.39); C307(0.94); C80(1.11)  LDD0742  [6]
 LDCM0426  CL37 HCT 116 C115(1.03); C29(1.15); C307(1.01); C80(0.94)  LDD0743  [6]
 LDCM0428  CL39 HCT 116 C115(0.98); C29(1.01); C307(0.86); C80(1.07)  LDD0745  [6]
 LDCM0429  CL4 HCT 116 C115(1.09); C29(1.47); C299(1.72); C307(1.72)  LDD0746  [6]
 LDCM0430  CL40 HCT 116 C115(1.18); C29(1.32); C307(1.04); C80(0.83)  LDD0747  [6]
 LDCM0431  CL41 HCT 116 C115(0.94); C29(1.56); C307(0.93); C80(0.91)  LDD0748  [6]
 LDCM0432  CL42 HCT 116 C115(0.95); C29(1.71); C307(1.13); C80(0.99)  LDD0749  [6]
 LDCM0433  CL43 HCT 116 C115(0.96); C29(1.08); C307(0.92); C80(0.90)  LDD0750  [6]
 LDCM0434  CL44 HCT 116 C115(1.13); C29(1.24); C307(0.86); C80(1.00)  LDD0751  [6]
 LDCM0435  CL45 HCT 116 C115(1.05); C29(1.16); C307(0.93); C80(0.86)  LDD0752  [6]
 LDCM0436  CL46 HCT 116 C115(1.09); C29(0.90); C299(1.19); C307(1.19)  LDD0753  [6]
 LDCM0437  CL47 HCT 116 C115(1.17); C29(0.94); C299(1.16); C307(1.16)  LDD0754  [6]
 LDCM0438  CL48 HCT 116 C115(1.31); C29(0.85); C299(1.36); C307(1.36)  LDD0755  [6]
 LDCM0439  CL49 HCT 116 C115(0.95); C29(0.81); C299(1.26); C307(1.26)  LDD0756  [6]
 LDCM0440  CL5 HCT 116 C115(1.06); C29(0.91); C299(1.12); C307(1.12)  LDD0757  [6]
 LDCM0441  CL50 HCT 116 C115(1.13); C29(1.07); C299(1.11); C307(1.11)  LDD0758  [6]
 LDCM0442  CL51 HCT 116 C115(1.13); C29(0.83); C299(1.17); C307(1.17)  LDD0759  [6]
 LDCM0443  CL52 HCT 116 C115(1.23); C29(1.02); C299(1.24); C307(1.24)  LDD0760  [6]
 LDCM0444  CL53 HCT 116 C115(1.25); C29(1.18); C299(1.74); C307(1.74)  LDD0761  [6]
 LDCM0445  CL54 HCT 116 C115(1.14); C29(1.09); C299(1.22); C307(1.22)  LDD0762  [6]
 LDCM0446  CL55 HCT 116 C115(0.92); C29(0.88); C299(1.05); C307(1.05)  LDD0763  [6]
 LDCM0447  CL56 HCT 116 C115(0.92); C29(1.19); C299(1.26); C307(1.26)  LDD0764  [6]
 LDCM0448  CL57 HCT 116 C115(1.09); C29(0.89); C299(1.15); C307(1.15)  LDD0765  [6]
 LDCM0449  CL58 HCT 116 C115(0.96); C29(1.16); C299(1.11); C307(1.11)  LDD0766  [6]
 LDCM0450  CL59 HCT 116 C115(1.07); C29(0.89); C299(1.10); C307(1.10)  LDD0767  [6]
 LDCM0451  CL6 HCT 116 C115(1.26); C29(0.94); C299(0.76); C307(0.76)  LDD0768  [6]
 LDCM0452  CL60 HCT 116 C115(1.11); C29(1.05); C299(1.12); C307(1.12)  LDD0769  [6]
 LDCM0453  CL61 HCT 116 C80(0.69)  LDD0770  [6]
 LDCM0454  CL62 HCT 116 C80(0.69)  LDD0771  [6]
 LDCM0455  CL63 HCT 116 C80(1.25)  LDD0772  [6]
 LDCM0456  CL64 HCT 116 C80(1.73)  LDD0773  [6]
 LDCM0457  CL65 HCT 116 C80(0.77)  LDD0774  [6]
 LDCM0458  CL66 HCT 116 C80(0.92)  LDD0775  [6]
 LDCM0459  CL67 HCT 116 C80(0.93)  LDD0776  [6]
 LDCM0460  CL68 HCT 116 C80(0.79)  LDD0777  [6]
 LDCM0461  CL69 HCT 116 C80(1.11)  LDD0778  [6]
 LDCM0462  CL7 HCT 116 C115(1.25); C29(0.87); C299(1.48); C307(1.48)  LDD0779  [6]
 LDCM0463  CL70 HCT 116 C80(0.94)  LDD0780  [6]
 LDCM0464  CL71 HCT 116 C80(1.06)  LDD0781  [6]
 LDCM0465  CL72 HCT 116 C80(0.97)  LDD0782  [6]
 LDCM0466  CL73 HCT 116 C80(0.98)  LDD0783  [6]
 LDCM0467  CL74 HCT 116 C80(0.91)  LDD0784  [6]
 LDCM0469  CL76 HCT 116 C29(0.97); C299(0.75); C307(0.75)  LDD0786  [6]
 LDCM0470  CL77 HCT 116 C29(0.87); C299(0.65); C307(0.65)  LDD0787  [6]
 LDCM0471  CL78 HCT 116 C29(0.83); C299(0.87); C307(0.87)  LDD0788  [6]
 LDCM0472  CL79 HCT 116 C29(1.00); C299(0.66); C307(0.66)  LDD0789  [6]
 LDCM0473  CL8 HCT 116 C115(0.84); C29(1.03); C299(0.92); C307(0.92)  LDD0790  [6]
 LDCM0474  CL80 HCT 116 C29(0.78); C299(0.76); C307(0.76)  LDD0791  [6]
 LDCM0475  CL81 HCT 116 C29(0.68); C299(0.78); C307(0.78)  LDD0792  [6]
 LDCM0476  CL82 HCT 116 C29(0.73); C299(0.69); C307(0.69)  LDD0793  [6]
 LDCM0477  CL83 HCT 116 C29(1.00); C299(0.80); C307(0.80)  LDD0794  [6]
 LDCM0478  CL84 HCT 116 C29(1.05); C299(0.65); C307(0.65)  LDD0795  [6]
 LDCM0479  CL85 HCT 116 C29(1.06); C299(0.71); C307(0.71)  LDD0796  [6]
 LDCM0480  CL86 HCT 116 C29(0.89); C299(0.69); C307(0.69)  LDD0797  [6]
 LDCM0481  CL87 HCT 116 C29(0.73); C299(1.00); C307(1.00)  LDD0798  [6]
 LDCM0482  CL88 HCT 116 C29(0.77); C299(0.77); C307(0.77)  LDD0799  [6]
 LDCM0483  CL89 HCT 116 C29(0.87); C299(0.83); C307(0.83)  LDD0800  [6]
 LDCM0484  CL9 HCT 116 C115(1.01); C29(1.01); C299(0.69); C307(0.69)  LDD0801  [6]
 LDCM0485  CL90 HCT 116 C29(0.80); C299(0.49); C307(0.49)  LDD0802  [6]
 LDCM0486  CL91 HCT 116 C115(0.58); C29(1.11); C299(0.67); C307(0.93)  LDD0803  [6]
 LDCM0487  CL92 HCT 116 C115(0.58); C29(1.12); C299(0.66); C307(0.93)  LDD0804  [6]
 LDCM0488  CL93 HCT 116 C115(1.06); C29(0.75); C299(0.55); C307(0.81)  LDD0805  [6]
 LDCM0489  CL94 HCT 116 C115(0.20); C29(0.95); C299(0.73); C307(0.88)  LDD0806  [6]
 LDCM0490  CL95 HCT 116 C115(0.82); C29(0.90); C299(0.67); C307(0.86)  LDD0807  [6]
 LDCM0491  CL96 HCT 116 C115(0.81); C29(0.81); C299(0.90); C307(0.94)  LDD0808  [6]
 LDCM0492  CL97 HCT 116 C115(0.74); C29(0.94); C299(0.74); C307(0.78)  LDD0809  [6]
 LDCM0493  CL98 HCT 116 C115(0.77); C29(1.01); C299(0.79); C307(0.81)  LDD0810  [6]
 LDCM0494  CL99 HCT 116 C115(0.84); C29(1.01); C299(0.79); C307(0.78)  LDD0811  [6]
 LDCM0495  E2913 HEK-293T C243(1.05); C115(0.95); C29(1.20); C36(1.15)  LDD1698  [17]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C96(1.04)  LDD1702  [18]
 LDCM0625  F8 Ramos C115(1.20); C96(1.43); C243(0.85); C29(1.33)  LDD2187  [19]
 LDCM0572  Fragment10 Ramos C115(0.81); C96(1.01); C243(0.53)  LDD2189  [19]
 LDCM0573  Fragment11 Ramos C115(9.60); C96(0.42); C243(1.07); C29(0.08)  LDD2190  [19]
 LDCM0574  Fragment12 Ramos C115(0.71); C96(1.23); C243(1.29); C29(0.53)  LDD2191  [19]
 LDCM0575  Fragment13 Ramos C115(1.00); C96(1.32); C243(1.48); C29(1.04)  LDD2192  [19]
 LDCM0576  Fragment14 Ramos C115(0.63); C96(0.70); C243(0.29); C29(0.63)  LDD2193  [19]
 LDCM0579  Fragment20 Ramos C115(0.58); C96(1.18); C243(0.95); C29(0.42)  LDD2194  [19]
 LDCM0580  Fragment21 Ramos C115(0.90); C96(1.35); C243(1.48); C29(1.01)  LDD2195  [19]
 LDCM0582  Fragment23 Ramos C115(1.46); C96(1.76); C243(2.10); C29(1.17)  LDD2196  [19]
 LDCM0578  Fragment27 Ramos C115(0.90); C96(1.71); C243(1.68); C29(1.08)  LDD2197  [19]
 LDCM0586  Fragment28 Ramos C115(1.03); C96(0.43); C243(0.60); C29(1.16)  LDD2198  [19]
 LDCM0588  Fragment30 Ramos C115(1.12); C96(1.96); C243(2.55); C29(0.54)  LDD2199  [19]
 LDCM0589  Fragment31 Ramos C115(0.80); C96(1.26); C243(1.48); C29(0.97)  LDD2200  [19]
 LDCM0590  Fragment32 Ramos C115(0.73); C96(0.85); C243(0.92); C29(0.61)  LDD2201  [19]
 LDCM0468  Fragment33 HCT 116 C80(0.97)  LDD0785  [6]
 LDCM0596  Fragment38 Ramos C115(0.69); C96(1.20); C243(1.33); C29(0.99)  LDD2203  [19]
 LDCM0566  Fragment4 Ramos C115(0.60); C96(0.81); C243(0.77); C29(1.75)  LDD2184  [19]
 LDCM0427  Fragment51 HCT 116 C115(0.80); C29(1.40); C307(1.24); C80(0.73)  LDD0744  [6]
 LDCM0610  Fragment52 Ramos C115(0.91); C96(1.53); C243(1.92); C29(0.78)  LDD2204  [19]
 LDCM0614  Fragment56 Ramos C115(1.11); C96(1.58); C243(1.72); C29(0.74)  LDD2205  [19]
 LDCM0569  Fragment7 Ramos C115(0.50); C96(0.80); C243(0.29); C29(1.01)  LDD2186  [19]
 LDCM0571  Fragment9 Ramos C115(0.93); C96(0.92); C243(0.67); C29(0.29)  LDD2188  [19]
 LDCM0116  HHS-0101 DM93 Y87(1.03)  LDD0264  [4]
 LDCM0117  HHS-0201 DM93 Y87(0.86)  LDD0265  [4]
 LDCM0118  HHS-0301 DM93 Y87(1.13)  LDD0266  [4]
 LDCM0119  HHS-0401 DM93 Y87(6.85)  LDD0267  [4]
 LDCM0120  HHS-0701 DM93 Y87(6.12)  LDD0268  [4]
 LDCM0107  IAA HeLa N.A.  LDD0221  [9]
 LDCM0022  KB02 HCT 116 C29(1.09)  LDD0080  [6]
 LDCM0023  KB03 HCT 116 C29(0.99)  LDD0081  [6]
 LDCM0024  KB05 HCT 116 C29(1.00)  LDD0082  [6]
 LDCM0627  NUDT7-COV-1 HEK-293T C115(1.09)  LDD2206  [20]
 LDCM0628  OTUB2-COV-1 HEK-293T C115(0.82)  LDD2207  [20]
 LDCM0131  RA190 MM1.R C115(1.08)  LDD0304  [21]
 LDCM0021  THZ1 HCT 116 C299(1.33); C307(1.33)  LDD2173  [6]

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
3 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
4 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
5 Global targeting of functional tyrosines using sulfur-triazole exchange chemistry. Nat Chem Biol. 2020 Feb;16(2):150-159. doi: 10.1038/s41589-019-0404-5. Epub 2019 Nov 25.
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
8 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
9 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
10 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
11 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
12 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
13 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
14 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
15 Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20.
Mass spectrometry data entry: PXD007570
16 Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.
17 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
18 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
19 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
20 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.
21 Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.