Details of the Probe

General Information of Probe

Probe ID
LDPC0458
Probe Name
C225
Synonyms
Z4282859816
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 313.4
Lipid-water partition coefficient (xlogp) 3.1
Rotatable Bond Count (rotbonds) 9
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C18H23N3O2
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[2-(2,6-dimethylphenoxy)ethyl]propanamide
Canonical SMILES
CC1=C(C(=CC=C1)C)OCCNC(=O)CCC2(N=N2)CCC#C
InChI
InChI=1S/C18H23N3O2/c1-4-5-10-18(20-21-18)11-9-16(22)19-12-13-23-17-14(2)7-6-8-15(17)3/h1,6-8H,5,9-13H2,2-3H3,(H,19,22)
InChIKey
LBDYZAGFEBROBP-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

126 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 5.03  LDD1898 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 5.82  LDD1898 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 6.32  LDD1898 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 7.73  LDD1898 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 7.78  LDD1898 
Acid ceramidase (ASAH1) LDTP05905 13.18  LDD1898 
ADP-dependent glucokinase (ADPGK) LDTP11127 5.58  LDD1898 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 6.45  LDD1898 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 5.78  LDD1898 
Arylsulfatase A (ARSA) LDTP02776 5.90  LDD1898 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 19.84  LDD1898 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 6.45  LDD1898 
ATPase GET3 (GET3) LDTP00836 5.03  LDD1898 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 5.39  LDD1898 
Beta-galactosidase (GLB1) LDTP02837 10.27  LDD1898 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 5.13  LDD1898 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 10.20  LDD1898 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 11.31  LDD1898 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 5.24  LDD1898 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 9.00  LDD1898 
Catechol O-methyltransferase (COMT) LDTP03145 6.15  LDD1898 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 5.46  LDD1898 
Ceramide synthase 1 (CERS1) LDTP03394 9.85  LDD1898 
Ceramide synthase 2 (CERS2) LDTP10329 7.41  LDD1898 
Choline/ethanolaminephosphotransferase 1 (CEPT1) LDTP14264 5.54  LDD1898 
Copper-transporting ATPase 2 (ATP7B) LDTP03779 6.15  LDD1898 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 9.19  LDD1898 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 10.27  LDD1898 
Cytochrome b5 type B (CYB5B) LDTP00697 24.25  LDD1898 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 5.10  LDD1898 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 8.63  LDD1898 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 5.28  LDD1898 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 9.65  LDD1898 
Delta(14)-sterol reductase TM7SF2 (TM7SF2) LDTP01389 11.63  LDD1898 
Delta(24)-sterol reductase (DHCR24) LDTP06375 8.51  LDD1898 
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) LDTP02362 5.43  LDD1898 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 4.99  LDD1898 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 5.50  LDD1898 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 6.59  LDD1898 
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETFDH) LDTP06511 8.75  LDD1898 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 7.26  LDD1898 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 10.85  LDD1898 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 5.98  LDD1898 
Epoxide hydrolase 1 (EPHX1) LDTP02175 5.58  LDD1898 
Exonuclease 1 (EXO1) LDTP13751 7.52  LDD1898 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 7.84  LDD1898 
Ferrochelatase, mitochondrial (FECH) LDTP03198 6.77  LDD1898 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 23.10  LDD1898 
GMP synthase [glutamine-hydrolyzing] (GMPS) LDTP04333 4.99  LDD1898 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 5.28  LDD1898 
Heme A synthase COX15 (COX15) LDTP07931 5.66  LDD1898 
Heme oxygenase 1 (HMOX1) LDTP02359 11.96  LDD1898 
Heme oxygenase 2 (HMOX2) LDTP03540 28.44  LDD1898 
Histone-lysine N-methyltransferase 2A (KMT2A) LDTP05396 5.46  LDD1898 
Holocytochrome c-type synthase (HCCS) LDTP04581 5.03  LDD1898 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 7.06  LDD1898 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 11.47  LDD1898 
Lanosterol synthase (LSS) LDTP04183 7.41  LDD1898 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 8.00  LDD1898 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 38.05  LDD1898 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 6.45  LDD1898 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 5.98  LDD1898 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 16.80  LDD1898 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 8.22  LDD1898 
Lysophospholipid acyltransferase 5 (LPCAT3) LDTP07504 5.90  LDD1898 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 6.45  LDD1898 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 15.03  LDD1898 
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) LDTP03858 7.01  LDD1898 
Lysosomal acid phosphatase (ACP2) LDTP02539 6.15  LDD1898 
Lysosomal alpha-glucosidase (GAA) LDTP02486 5.74  LDD1898 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 13.83  LDD1898 
Lysosomal protective protein (CTSA) LDTP02505 7.21  LDD1898 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 7.31  LDD1898 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 20.25  LDD1898 
Minor histocompatibility antigen H13 (HM13) LDTP09396 5.24  LDD1898 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 6.23  LDD1898 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 16.34  LDD1898 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 8.57  LDD1898 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 7.52  LDD1898 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 5.62  LDD1898 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 17.75  LDD1898 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 8.94  LDD1898 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 36.25  LDD1898 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 10.13  LDD1898 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 25.63  LDD1898 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 8.17  LDD1898 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 10.41  LDD1898 
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (PAOX) LDTP07620 5.98  LDD1898 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 5.31  LDD1898 
Phospholipase A2 group XV (PLA2G15) LDTP09088 9.85  LDD1898 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 5.03  LDD1898 
Polyamine-transporting ATPase 13A2 (ATP13A2) LDTP12386 6.02  LDD1898 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 4.92  LDD1898 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 8.69  LDD1898 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 12.30  LDD1898 
Presenilin-associated rhomboid-like protein, mitochondrial (PARL) LDTP11852 5.35  LDD1898 
Probable ATP-dependent RNA helicase DDX10 (DDX10) LDTP05785 5.62  LDD1898 
Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (ALG8) LDTP11290 5.31  LDD1898 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 11.24  LDD1898 
Prostaglandin reductase 3 (PTGR3) LDTP15422 32.22  LDD1898 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 8.06  LDD1898 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 5.24  LDD1898 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 6.82  LDD1898 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 10.13  LDD1898 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 9.58  LDD1898 
Ras-related protein Rab-24 (RAB24) LDTP10020 5.13  LDD1898 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 14.83  LDD1898 
Ribosomal protein S6 kinase alpha-1 (RPS6KA1) LDTP06384 5.74  LDD1898 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 10.34  LDD1898 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 5.24  LDD1898 
Serine/threonine-protein phosphatase 4 regulatory subunit 3A (PPP4R3A) LDTP07417 6.73  LDD1898 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 11.79  LDD1898 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 12.55  LDD1898 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 12.04  LDD1898 
Sphingosine kinase 2 (SPHK2) LDTP12490 5.94  LDD1898 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 6.87  LDD1898 
TLC domain-containing protein 1 (TLCD1) LDTP10182 7.62  LDD1898 
Trimethyllysine dioxygenase, mitochondrial (TMLHE) LDTP12679 5.58  LDD1898 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 9.25  LDD1898 
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) LDTP11867 9.00  LDD1898 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 6.06  LDD1898 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 5.62  LDD1898 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 6.36  LDD1898 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 5.35  LDD1898 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 20.97  LDD1898 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 4.96  LDD1898 
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⏷ Show the Full List of 126 Enzyme
91 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 5.70  LDD1898 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 7.26  LDD1898 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 5.50  LDD1898 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 5.39  LDD1898 
Anoctamin-10 (ANO10) LDTP12704 5.74  LDD1898 
ATP synthase subunit a (MT-ATP6) LDTP01804 24.42  LDD1898 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 9.85  LDD1898 
BRI3-binding protein (BRI3BP) LDTP15648 11.39  LDD1898 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 5.43  LDD1898 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 16.34  LDD1898 
Derlin-1 (DERL1) LDTP11245 7.01  LDD1898 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 14.42  LDD1898 
Essential MCU regulator, mitochondrial (SMDT1) LDTP11927 14.62  LDD1898 
H(+)/Cl(-) exchange transporter 7 (CLCN7) LDTP04463 10.63  LDD1898 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 6.41  LDD1898 
Integral membrane protein 2C (ITM2C) LDTP12451 7.46  LDD1898 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 5.62  LDD1898 
Lysosome membrane protein 2 (SCARB2) LDTP06034 25.63  LDD1898 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 5.21  LDD1898 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 8.94  LDD1898 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 5.58  LDD1898 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 8.40  LDD1898 
Metal cation symporter ZIP14 (SLC39A14) LDTP06293 5.28  LDD1898 
Metaxin-1 (MTX1) LDTP05900 6.96  LDD1898 
MICOS complex subunit MIC26 (APOO) LDTP11250 5.35  LDD1898 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 5.62  LDD1898 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 6.92  LDD1898 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 7.11  LDD1898 
Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) LDTP08279 9.32  LDD1898 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 11.00  LDD1898 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 5.06  LDD1898 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 9.65  LDD1898 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD1898 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 6.19  LDD1898 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 12.64  LDD1898 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 5.54  LDD1898 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 13.00  LDD1898 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 5.54  LDD1898 
Mitoguardin 1 (MIGA1) LDTP09028 7.89  LDD1898 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 8.75  LDD1898 
Mpv17-like protein 2 (MPV17L2) LDTP14952 13.09  LDD1898 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 10.34  LDD1898 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 6.73  LDD1898 
Nucleoporin NDC1 (NDC1) LDTP11213 9.13  LDD1898 
Nucleoporin Nup37 (NUP37) LDTP09203 5.54  LDD1898 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 5.06  LDD1898 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 14.12  LDD1898 
PRA1 family protein 2 (PRAF2) LDTP01060 5.54  LDD1898 
Probable mitochondrial glutathione transporter SLC25A40 (SLC25A40) LDTP18053 4.92  LDD1898 
Prosaposin (PSAP) LDTP02215 12.91  LDD1898 
Protein FAM8A1 (FAM8A1) LDTP16190 11.79  LDD1898 
Protein GPR107 (GPR107) LDTP07236 13.18  LDD1898 
Protein GPR108 (GPR108) LDTP12383 8.75  LDD1898 
Protein spinster homolog 1 (SPNS1) LDTP11844 6.63  LDD1898 
Protein tweety homolog 3 (TTYH3) LDTP11615 19.84  LDD1898 
Protein wntless homolog (WLS) LDTP07156 5.54  LDD1898 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 7.62  LDD1898 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 5.90  LDD1898 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 10.93  LDD1898 
Sideroflexin-4 (SFXN4) LDTP07531 6.73  LDD1898 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 12.21  LDD1898 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 18.38  LDD1898 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 14.93  LDD1898 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 7.84  LDD1898 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 7.84  LDD1898 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 9.58  LDD1898 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 8.57  LDD1898 
Stomatin (STOM) LDTP03380 6.92  LDD1898 
Surfeit locus protein 4 (SURF4) LDTP00592 8.75  LDD1898 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 6.02  LDD1898 
Tetraspanin-10 (TSPAN10) LDTP15967 20.25  LDD1898 
Tetraspanin-3 (TSPAN3) LDTP16813 24.76  LDD1898 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 22.01  LDD1898 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 15.67  LDD1898 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 6.92  LDD1898 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 11.16  LDD1898 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 5.17  LDD1898 
Transmembrane protein 126A (TMEM126A) LDTP15948 20.25  LDD1898 
Transmembrane protein 14C (TMEM14C) LDTP12979 4.92  LDD1898 
Transmembrane protein 160 (TMEM160) LDTP20002 13.83  LDD1898 
Transmembrane protein 199 (TMEM199) LDTP08881 11.63  LDD1898 
Transmembrane protein 230 (TMEM230) LDTP10065 6.50  LDD1898 
Transmembrane protein 245 (TMEM245) LDTP15979 6.77  LDD1898 
Transmembrane protein 33 (TMEM33) LDTP04787 5.43  LDD1898 
Transmembrane protein 59 (TMEM59) LDTP11406 5.10  LDD1898 
Transmembrane protein 87A (TMEM87A) LDTP15481 16.22  LDD1898 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 9.92  LDD1898 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 25.81  LDD1898 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 22.78  LDD1898 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 5.46  LDD1898 
Zinc transporter 7 (SLC30A7) LDTP09180 6.68  LDD1898 
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⏷ Show the Full List of 91 Transporter and channel
3 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DNA polymerase epsilon subunit 4 (POLE4) LDTP12471 5.90  LDD1898 
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 5.78  LDD1898 
PHD finger-like domain-containing protein 5A (PHF5A) LDTP08006 5.94  LDD1898 
------------------------------------------------------------------------------------
1 GPCR Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Membrane progestin receptor alpha (PAQR7) LDTP15303 19.84  LDD1898 
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1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Leukocyte surface antigen CD47 (CD47) LDTP05572 5.35  LDD1898 
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63 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor-like protein 6-interacting protein 6 (ARL6IP6) LDTP15434 5.70  LDD1898 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 6.77  LDD1898 
Apolipoprotein L2 (APOL2) LDTP11076 27.28  LDD1898 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 7.11  LDD1898 
CCR4-NOT transcription complex subunit 2 (CNOT2) LDTP12925 6.06  LDD1898 
Clustered mitochondria protein homolog (CLUH) LDTP14486 12.91  LDD1898 
Collectin-12 (COLEC12) LDTP07031 4.92  LDD1898 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 9.71  LDD1898 
DENN domain-containing protein 11 (DENND11) LDTP16577 5.50  LDD1898 
Dymeclin (DYM) LDTP08000 5.74  LDD1898 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 5.90  LDD1898 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 8.34  LDD1898 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 31.78  LDD1898 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 32.45  LDD1898 
Ganglioside GM2 activator (GM2A) LDTP02927 6.28  LDD1898 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 7.16  LDD1898 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 5.17  LDD1898 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 5.24  LDD1898 
Kinesin light chain 2 (KLC2) LDTP11695 5.28  LDD1898 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 5.28  LDD1898 
Large proline-rich protein BAG6 (BAG6) LDTP04094 5.50  LDD1898 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 9.38  LDD1898 
Lipid droplet assembly factor 1 (LDAF1) LDTP10116 5.90  LDD1898 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 26.72  LDD1898 
Membralin (TMEM259) LDTP14939 8.34  LDD1898 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 13.09  LDD1898 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 17.15  LDD1898 
Nicastrin (NCSTN) LDTP09787 5.39  LDD1898 
Nucleobindin-1 (NUCB1) LDTP05375 13.18  LDD1898 
Nucleobindin-2 (NUCB2) LDTP05160 20.53  LDD1898 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 4.99  LDD1898 
Nurim (NRM) LDTP08606 4.99  LDD1898 
Optic atrophy 3 protein (OPA3) LDTP16006 10.56  LDD1898 
p53 and DNA damage-regulated protein 1 (PDRG1) LDTP16099 15.35  LDD1898 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 29.45  LDD1898 
Protein CEBPZOS (CEBPZOS) LDTP18883 11.63  LDD1898 
Protein FAM114A2 (FAM114A2) LDTP16080 10.20  LDD1898 
Protein FAM162A (FAM162A) LDTP10056 9.78  LDD1898 
Protein jagunal homolog 1 (JAGN1) LDTP08904 5.50  LDD1898 
Protein LYRIC (MTDH) LDTP08224 6.19  LDD1898 
Protein SYS1 homolog (SYS1) LDTP08796 17.27  LDD1898 
Protein unc-119 homolog A (UNC119) LDTP05868 12.04  LDD1898 
Protein YIF1A (YIF1A) LDTP01494 5.06  LDD1898 
Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 4.99  LDD1898 
Reticulocalbin-2 (RCN2) LDTP06097 4.96  LDD1898 
Reticulon-2 (RTN2) LDTP01167 5.13  LDD1898 
Reticulon-3 (RTN3) LDTP01522 19.70  LDD1898 
Reticulon-4 (RTN4) LDTP12412 11.39  LDD1898 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 6.59  LDD1898 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 5.13  LDD1898 
Surfeit locus protein 1 (SURF1) LDTP06404 5.82  LDD1898 
Synaptic vesicle glycoprotein 2A (SV2A) LDTP07934 4.96  LDD1898 
Synaptogyrin-2 (SYNGR2) LDTP00859 4.99  LDD1898 
Syntaxin-18 (STX18) LDTP13086 7.36  LDD1898 
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) LDTP14263 9.65  LDD1898 
Tetraspanin-6 (TSPAN6) LDTP14458 14.03  LDD1898 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 5.39  LDD1898 
TraB domain-containing protein (TRABD) LDTP19963 5.94  LDD1898 
Transmembrane protein 161A (TMEM161A) LDTP12762 4.96  LDD1898 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 7.06  LDD1898 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 11.96  LDD1898 
UPF0488 protein C8orf33 (C8orf33) LDTP12025 6.50  LDD1898 
Vacuolar protein sorting-associated protein 37C (VPS37C) LDTP00071 7.46  LDD1898 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1898 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587