Details of the Target

General Information of Target

Target ID	LDTP08728
Target Name	Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1)
Gene Name	VKORC1L1
Gene ID	154807
Synonyms	Vitamin K epoxide reductase complex subunit 1-like protein 1; VKORC1-like protein 1; EC 1.17.4.4
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MAAPVLLRVSVPRWERVARYAVCAAGILLSIYAYHVEREKERDPEHRALCDLGPWVKCSA ALASRWGRGFGLLGSIFGKDGVLNQPNSVFGLIFYILQLLLGMTASAVAALILMTSSIMS VVGSLYLAYILYFVLKEFCIICIVTYVLNFLLLIINYKRLVYLNEAWKRQLQPKQD
Target Bioclass	Enzyme
Family	VKOR family
Subcellular location	Endoplasmic reticulum membrane
Function	Involved in vitamin K metabolism. Can reduce inactive vitamin K 2,3-epoxide to active vitamin K, and may contribute to vitamin K-mediated protection against oxidative stress. Plays a role in vitamin K-dependent gamma-carboxylation of Glu residues in target proteins.
Uniprot ID	Q8N0U8
Ensemble ID	ENST00000360768.5
HGNC ID	HGNC:21492

Target Site Mutations in Different Cell Lines

Cell line	Mutation details			Probe for labeling this protein in this cell
MSTO211H	Substitution: p.P4A			DBIA Probe Info

Probe(s) Labeling This Target

ABPP Probe

Click To Hide/Show 22 Probe Related to This Target

Probe name	Binding Site(Ratio)	Interaction ID	Ref
CHEMBL5175495 Probe Info	6.37	LDD0196	[1]
STPyne Probe Info	K57(6.38)	LDD0277	[2]
JZ128-DTB Probe Info	N.A.	LDD0462	[3]
BTD Probe Info	C58(1.15)	LDD2114	[4]
Jackson_14 Probe Info	2.00	LDD0123	[5]
AHL-Pu-1 Probe Info	C50(2.47)	LDD0173	[6]
HPAP Probe Info	3.01	LDD0063	[7]
DBIA Probe Info	C50(3.07)	LDD0080	[8]
4-Iodoacetamidophenylacetylene Probe Info	N.A.	LDD0038	[9]
IA-alkyne Probe Info	N.A.	LDD0036	[9]
Lodoacetamide azide Probe Info	C50(0.00); C58(0.00)	LDD0037	[9]
TFBX Probe Info	C58(0.00); C50(0.00)	LDD0027	[10]
WYneN Probe Info	N.A.	LDD0021	[11]
WYneO Probe Info	N.A.	LDD0022	[11]
Compound 10 Probe Info	C50(0.00); C58(0.00)	LDD2216	[12]
IPM Probe Info	C50(0.00); C58(0.00)	LDD0005	[11]
NPM Probe Info	N.A.	LDD0016	[11]
YN-1 Probe Info	N.A.	LDD0447	[13]
Acrolein Probe Info	N.A.	LDD0217	[14]
Crotonaldehyde Probe Info	N.A.	LDD0219	[14]
Methacrolein Probe Info	N.A.	LDD0218	[14]
NAIA_5 Probe Info	C50(0.00); C58(0.00); C23(0.00)	LDD2223	[15]

PAL-AfBPP Probe

Click To Hide/Show 115 Probe Related to This Target

Probe name	Binding Site(Ratio)	Interaction ID	Ref
C004 Probe Info	18.13	LDD1714	[16]
C010 Probe Info	14.32	LDD1719	[16]
C011 Probe Info	5.21	LDD1720	[16]
C022 Probe Info	29.65	LDD1728	[16]
C026 Probe Info	13.09	LDD1732	[16]
C039 Probe Info	7.57	LDD1739	[16]
C040 Probe Info	13.09	LDD1740	[16]
C041 Probe Info	9.06	LDD1741	[16]
C049 Probe Info	16.34	LDD1747	[16]
C055 Probe Info	14.52	LDD1752	[16]
C056 Probe Info	28.05	LDD1753	[16]
C063 Probe Info	26.54	LDD1760	[16]
C064 Probe Info	9.00	LDD1761	[16]
C067 Probe Info	6.59	LDD1763	[16]
C070 Probe Info	44.63	LDD1766	[16]
C072 Probe Info	22.94	LDD1768	[16]
C082 Probe Info	8.40	LDD1774	[16]
C087 Probe Info	15.67	LDD1779	[16]
C091 Probe Info	14.32	LDD1782	[16]
C092 Probe Info	59.71	LDD1783	[16]
C094 Probe Info	79.34	LDD1785	[16]
C095 Probe Info	13.55	LDD1786	[16]
C098 Probe Info	10.13	LDD1787	[16]
C100 Probe Info	12.30	LDD1789	[16]
C106 Probe Info	35.51	LDD1793	[16]
C107 Probe Info	16.00	LDD1794	[16]
C108 Probe Info	10.06	LDD1795	[16]
C112 Probe Info	37.01	LDD1799	[16]
C129 Probe Info	4.99	LDD1811	[16]
C130 Probe Info	7.67	LDD1812	[16]
C134 Probe Info	40.79	LDD1816	[16]
C135 Probe Info	18.38	LDD1817	[16]
C141 Probe Info	86.82	LDD1823	[16]
C143 Probe Info	32.45	LDD1825	[16]
C153 Probe Info	20.53	LDD1834	[16]
C156 Probe Info	20.11	LDD1836	[16]
C159 Probe Info	15.35	LDD1839	[16]
C160 Probe Info	19.56	LDD1840	[16]
C161 Probe Info	25.63	LDD1841	[16]
C163 Probe Info	8.57	LDD1843	[16]
C169 Probe Info	99.73	LDD1849	[16]
C177 Probe Info	11.96	LDD1856	[16]
C178 Probe Info	85.04	LDD1857	[16]
C186 Probe Info	28.64	LDD1864	[16]
C187 Probe Info	18.25	LDD1865	[16]
C194 Probe Info	28.64	LDD1870	[16]
C196 Probe Info	17.15	LDD1872	[16]
C198 Probe Info	34.06	LDD1874	[16]
C210 Probe Info	41.64	LDD1884	[16]
C211 Probe Info	32.45	LDD1885	[16]
C213 Probe Info	23.10	LDD1887	[16]
C218 Probe Info	24.93	LDD1892	[16]
C219 Probe Info	20.53	LDD1893	[16]
C220 Probe Info	93.05	LDD1894	[16]
C222 Probe Info	5.54	LDD1896	[16]
C225 Probe Info	20.97	LDD1898	[16]
C226 Probe Info	7.11	LDD1899	[16]
C228 Probe Info	45.25	LDD1901	[16]
C229 Probe Info	16.56	LDD1902	[16]
C231 Probe Info	99.04	LDD1904	[16]
C232 Probe Info	99.73	LDD1905	[16]
C233 Probe Info	33.13	LDD1906	[16]
C235 Probe Info	41.36	LDD1908	[16]
C245 Probe Info	17.63	LDD1918	[16]
C246 Probe Info	79.34	LDD1919	[16]
C249 Probe Info	37.01	LDD1922	[16]
C264 Probe Info	35.02	LDD1935	[16]
C265 Probe Info	16.45	LDD1936	[16]
C270 Probe Info	8.94	LDD1940	[16]
C273 Probe Info	8.57	LDD1943	[16]
C277 Probe Info	48.50	LDD1947	[16]
C278 Probe Info	48.50	LDD1948	[16]
C280 Probe Info	10.06	LDD1950	[16]
C282 Probe Info	51.98	LDD1952	[16]
C287 Probe Info	21.56	LDD1957	[16]
C288 Probe Info	28.25	LDD1958	[16]
C289 Probe Info	47.84	LDD1959	[16]
C293 Probe Info	30.06	LDD1963	[16]
C296 Probe Info	44.32	LDD1966	[16]
C299 Probe Info	9.99	LDD1968	[16]
C305 Probe Info	10.70	LDD1974	[16]
C314 Probe Info	64.89	LDD1981	[16]
C317 Probe Info	7.21	LDD1983	[16]
C327 Probe Info	10.06	LDD1991	[16]
C343 Probe Info	48.17	LDD2005	[16]
C348 Probe Info	20.68	LDD2009	[16]
C349 Probe Info	51.63	LDD2010	[16]
C350 Probe Info	99.73	LDD2011	[16]
C353 Probe Info	6.41	LDD2014	[16]
C355 Probe Info	32.22	LDD2016	[16]
C356 Probe Info	31.56	LDD2017	[16]
C357 Probe Info	18.77	LDD2018	[16]
C362 Probe Info	74.54	LDD2023	[16]
C363 Probe Info	41.93	LDD2024	[16]
C364 Probe Info	23.92	LDD2025	[16]
C373 Probe Info	38.59	LDD2033	[16]
C376 Probe Info	6.59	LDD2036	[16]
C378 Probe Info	10.63	LDD2037	[16]
C380 Probe Info	16.68	LDD2039	[16]
C382 Probe Info	14.32	LDD2041	[16]
C390 Probe Info	99.73	LDD2049	[16]
C396 Probe Info	7.21	LDD2055	[16]
C399 Probe Info	7.94	LDD2058	[16]
C400 Probe Info	5.13	LDD2059	[16]
C409 Probe Info	5.17	LDD2066	[16]
C413 Probe Info	34.06	LDD2069	[16]
C419 Probe Info	43.71	LDD2074	[16]
C420 Probe Info	26.17	LDD2075	[16]
C421 Probe Info	15.14	LDD2076	[16]
C422 Probe Info	37.01	LDD2077	[16]
C423 Probe Info	21.11	LDD2078	[16]
C429 Probe Info	19.97	LDD2084	[16]
C431 Probe Info	31.78	LDD2086	[16]
C433 Probe Info	16.00	LDD2088	[16]
OEA-DA Probe Info	7.97	LDD0046	[17]

Competitor(s) Related to This Target

Competitor ID	Name	Cell line	Binding Site(Ratio)	Interaction ID	Ref
LDCM0548	1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one	MDA-MB-231	C58(1.08)	LDD2142	[4]
LDCM0026	4SU-RNA+native RNA	HEK-293T	C50(2.47)	LDD0173	[6]
LDCM0214	AC1	HCT 116	C50(1.01); C58(1.20)	LDD0531	[8]
LDCM0215	AC10	HCT 116	C50(0.89); C58(1.38)	LDD0532	[8]
LDCM0216	AC100	HCT 116	C50(0.74); C58(0.91)	LDD0533	[8]
LDCM0217	AC101	HCT 116	C50(0.67); C58(0.85)	LDD0534	[8]
LDCM0218	AC102	HCT 116	C50(0.67); C58(0.79)	LDD0535	[8]
LDCM0219	AC103	HCT 116	C50(0.69); C58(0.87)	LDD0536	[8]
LDCM0220	AC104	HCT 116	C50(0.71); C58(0.72)	LDD0537	[8]
LDCM0221	AC105	HCT 116	C50(0.67); C58(0.98)	LDD0538	[8]
LDCM0222	AC106	HCT 116	C50(0.67); C58(1.54)	LDD0539	[8]
LDCM0223	AC107	HCT 116	C50(0.78); C58(1.10)	LDD0540	[8]
LDCM0224	AC108	HCT 116	C50(0.71); C58(1.13)	LDD0541	[8]
LDCM0225	AC109	HCT 116	C50(0.74); C58(0.72)	LDD0542	[8]
LDCM0226	AC11	HCT 116	C50(0.85); C58(1.07)	LDD0543	[8]
LDCM0227	AC110	HCT 116	C50(0.76); C58(1.18)	LDD0544	[8]
LDCM0228	AC111	HCT 116	C50(0.72); C58(1.10)	LDD0545	[8]
LDCM0229	AC112	HCT 116	C50(0.75); C58(1.16)	LDD0546	[8]
LDCM0230	AC113	HCT 116	C50(1.01); C58(1.10)	LDD0547	[8]
LDCM0231	AC114	HCT 116	C50(0.93); C58(1.14)	LDD0548	[8]
LDCM0232	AC115	HCT 116	C50(0.86); C58(0.97)	LDD0549	[8]
LDCM0233	AC116	HCT 116	C50(0.88); C58(1.02)	LDD0550	[8]
LDCM0234	AC117	HCT 116	C50(0.91); C58(1.10)	LDD0551	[8]
LDCM0235	AC118	HCT 116	C50(0.96); C58(1.08)	LDD0552	[8]
LDCM0236	AC119	HCT 116	C50(0.92); C58(1.00)	LDD0553	[8]
LDCM0237	AC12	HCT 116	C50(0.98); C58(1.01)	LDD0554	[8]
LDCM0238	AC120	HCT 116	C50(0.95); C58(0.83)	LDD0555	[8]
LDCM0239	AC121	HCT 116	C50(1.00); C58(1.02)	LDD0556	[8]
LDCM0240	AC122	HCT 116	C50(0.90); C58(1.04)	LDD0557	[8]
LDCM0241	AC123	HCT 116	C50(1.04); C58(0.89)	LDD0558	[8]
LDCM0242	AC124	HCT 116	C50(0.96); C58(1.07)	LDD0559	[8]
LDCM0243	AC125	HCT 116	C50(0.92); C58(1.18)	LDD0560	[8]
LDCM0244	AC126	HCT 116	C50(0.98); C58(1.09)	LDD0561	[8]
LDCM0245	AC127	HCT 116	C50(0.93); C58(1.02)	LDD0562	[8]
LDCM0246	AC128	HCT 116	C50(1.04); C58(1.50)	LDD0563	[8]
LDCM0247	AC129	HCT 116	C50(0.95); C58(1.62)	LDD0564	[8]
LDCM0249	AC130	HCT 116	C50(0.94); C58(1.43)	LDD0566	[8]
LDCM0250	AC131	HCT 116	C50(0.98); C58(1.77)	LDD0567	[8]
LDCM0251	AC132	HCT 116	C50(1.09); C58(1.55)	LDD0568	[8]
LDCM0252	AC133	HCT 116	C50(1.03); C58(1.61)	LDD0569	[8]
LDCM0253	AC134	HCT 116	C50(1.02); C58(1.58)	LDD0570	[8]
LDCM0254	AC135	HCT 116	C50(1.00); C58(1.56)	LDD0571	[8]
LDCM0255	AC136	HCT 116	C50(1.04); C58(1.29)	LDD0572	[8]
LDCM0256	AC137	HCT 116	C50(1.01); C58(1.26)	LDD0573	[8]
LDCM0257	AC138	HCT 116	C50(0.99); C58(1.42)	LDD0574	[8]
LDCM0258	AC139	HCT 116	C50(1.08); C58(1.57)	LDD0575	[8]
LDCM0259	AC14	HCT 116	C50(0.81); C58(1.14)	LDD0576	[8]
LDCM0260	AC140	HCT 116	C50(1.10); C58(1.64)	LDD0577	[8]
LDCM0261	AC141	HCT 116	C50(1.03); C58(1.59)	LDD0578	[8]
LDCM0262	AC142	HCT 116	C50(1.03); C58(1.40)	LDD0579	[8]
LDCM0263	AC143	HCT 116	C58(0.83); C50(0.88)	LDD0580	[8]
LDCM0264	AC144	HCT 116	C50(0.74); C58(0.90)	LDD0581	[8]
LDCM0265	AC145	HCT 116	C58(0.83); C50(0.90)	LDD0582	[8]
LDCM0266	AC146	HCT 116	C58(0.62); C50(0.71)	LDD0583	[8]
LDCM0267	AC147	HCT 116	C58(0.78); C50(0.81)	LDD0584	[8]
LDCM0268	AC148	HCT 116	C58(0.75); C50(0.79)	LDD0585	[8]
LDCM0269	AC149	HCT 116	C50(0.73); C58(0.83)	LDD0586	[8]
LDCM0270	AC15	HCT 116	C50(0.83); C58(1.12)	LDD0587	[8]
LDCM0271	AC150	HCT 116	C58(0.71); C50(0.88)	LDD0588	[8]
LDCM0272	AC151	HCT 116	C58(0.75); C50(0.81)	LDD0589	[8]
LDCM0273	AC152	HCT 116	C58(0.65); C50(0.77)	LDD0590	[8]
LDCM0274	AC153	HCT 116	C58(0.74); C50(0.80)	LDD0591	[8]
LDCM0621	AC154	HCT 116	C50(0.75); C58(0.59)	LDD2158	[8]
LDCM0622	AC155	HCT 116	C50(0.75); C58(0.89)	LDD2159	[8]
LDCM0623	AC156	HCT 116	C50(0.89); C58(0.71)	LDD2160	[8]
LDCM0624	AC157	HCT 116	C50(0.84); C58(0.58)	LDD2161	[8]
LDCM0276	AC17	HCT 116	C58(1.17); C50(1.21)	LDD0593	[8]
LDCM0277	AC18	HCT 116	C58(1.02); C50(1.13)	LDD0594	[8]
LDCM0278	AC19	HCT 116	C50(1.02); C58(1.07)	LDD0595	[8]
LDCM0279	AC2	HCT 116	C50(1.12); C58(1.27)	LDD0596	[8]
LDCM0280	AC20	HCT 116	C58(0.97); C50(1.21)	LDD0597	[8]
LDCM0281	AC21	HCT 116	C50(1.12); C58(1.21)	LDD0598	[8]
LDCM0282	AC22	HCT 116	C50(0.97); C58(1.16)	LDD0599	[8]
LDCM0283	AC23	HCT 116	C58(1.11); C50(1.16)	LDD0600	[8]
LDCM0284	AC24	HCT 116	C58(0.99); C50(1.03)	LDD0601	[8]
LDCM0285	AC25	HCT 116	C50(0.93); C58(1.16)	LDD0602	[8]
LDCM0286	AC26	HCT 116	C50(0.81); C58(0.93)	LDD0603	[8]
LDCM0287	AC27	HCT 116	C50(0.84); C58(1.07)	LDD0604	[8]
LDCM0288	AC28	HCT 116	C50(0.95); C58(1.45)	LDD0605	[8]
LDCM0289	AC29	HCT 116	C50(0.79); C58(1.06)	LDD0606	[8]
LDCM0290	AC3	HCT 116	C50(1.18); C58(1.42)	LDD0607	[8]
LDCM0291	AC30	HCT 116	C50(0.80); C58(1.26)	LDD0608	[8]
LDCM0292	AC31	HCT 116	C50(0.85); C58(1.07)	LDD0609	[8]
LDCM0293	AC32	HCT 116	C50(0.82); C58(1.26)	LDD0610	[8]
LDCM0294	AC33	HCT 116	C50(0.81); C58(1.28)	LDD0611	[8]
LDCM0295	AC34	HCT 116	C50(0.86); C58(1.05)	LDD0612	[8]
LDCM0296	AC35	HCT 116	C58(0.83); C50(1.00)	LDD0613	[8]
LDCM0297	AC36	HCT 116	C58(0.73); C50(1.09)	LDD0614	[8]
LDCM0298	AC37	HCT 116	C58(0.89); C50(1.07)	LDD0615	[8]
LDCM0299	AC38	HCT 116	C50(0.94); C58(1.02)	LDD0616	[8]
LDCM0300	AC39	HCT 116	C58(0.91); C50(1.04)	LDD0617	[8]
LDCM0301	AC4	HCT 116	C50(1.11); C58(1.30)	LDD0618	[8]
LDCM0302	AC40	HCT 116	C58(0.86); C50(1.10)	LDD0619	[8]
LDCM0303	AC41	HCT 116	C58(0.83); C50(1.01)	LDD0620	[8]
LDCM0304	AC42	HCT 116	C58(0.96); C50(1.03)	LDD0621	[8]
LDCM0305	AC43	HCT 116	C58(0.73); C50(1.05)	LDD0622	[8]
LDCM0306	AC44	HCT 116	C58(1.00); C50(1.02)	LDD0623	[8]
LDCM0307	AC45	HCT 116	C58(0.93); C50(1.05)	LDD0624	[8]
LDCM0308	AC46	HCT 116	C50(0.91); C58(1.11)	LDD0625	[8]
LDCM0309	AC47	HCT 116	C58(0.95); C50(1.00)	LDD0626	[8]
LDCM0310	AC48	HCT 116	C50(0.89); C58(1.17)	LDD0627	[8]
LDCM0311	AC49	HCT 116	C50(0.96); C58(1.21)	LDD0628	[8]
LDCM0312	AC5	HCT 116	C50(1.25); C58(1.35)	LDD0629	[8]
LDCM0313	AC50	HCT 116	C50(0.92); C58(1.23)	LDD0630	[8]
LDCM0314	AC51	HCT 116	C58(1.01); C50(1.02)	LDD0631	[8]
LDCM0315	AC52	HCT 116	C50(1.02); C58(1.27)	LDD0632	[8]
LDCM0316	AC53	HCT 116	C50(0.92); C58(1.02)	LDD0633	[8]
LDCM0317	AC54	HCT 116	C50(0.96); C58(1.12)	LDD0634	[8]
LDCM0318	AC55	HCT 116	C50(1.00); C58(1.07)	LDD0635	[8]
LDCM0319	AC56	HCT 116	C58(0.96); C50(1.06)	LDD0636	[8]
LDCM0320	AC57	HCT 116	C58(0.91); C50(1.03)	LDD0637	[8]
LDCM0321	AC58	HCT 116	C50(0.93); C58(1.03)	LDD0638	[8]
LDCM0322	AC59	HCT 116	C50(1.03); C58(1.10)	LDD0639	[8]
LDCM0323	AC6	HCT 116	C50(0.88); C58(1.25)	LDD0640	[8]
LDCM0324	AC60	HCT 116	C50(0.99); C58(1.01)	LDD0641	[8]
LDCM0325	AC61	HCT 116	C50(0.91); C58(0.99)	LDD0642	[8]
LDCM0326	AC62	HCT 116	C50(1.03); C58(1.15)	LDD0643	[8]
LDCM0327	AC63	HCT 116	C50(1.12); C58(1.37)	LDD0644	[8]
LDCM0328	AC64	HCT 116	C58(0.94); C50(1.07)	LDD0645	[8]
LDCM0329	AC65	HCT 116	C58(1.11); C50(1.13)	LDD0646	[8]
LDCM0330	AC66	HCT 116	C50(1.10); C58(1.15)	LDD0647	[8]
LDCM0331	AC67	HCT 116	C50(1.04); C58(1.09)	LDD0648	[8]
LDCM0332	AC68	HCT 116	C58(0.94); C50(1.00)	LDD0649	[8]
LDCM0333	AC69	HCT 116	C58(0.86); C50(1.05)	LDD0650	[8]
LDCM0334	AC7	HCT 116	C50(1.02); C58(1.44)	LDD0651	[8]
LDCM0335	AC70	HCT 116	C50(1.03); C58(1.12)	LDD0652	[8]
LDCM0336	AC71	HCT 116	C58(0.92); C50(1.03)	LDD0653	[8]
LDCM0337	AC72	HCT 116	C50(1.03); C58(1.04)	LDD0654	[8]
LDCM0338	AC73	HCT 116	C50(1.07); C58(1.10)	LDD0655	[8]
LDCM0339	AC74	HCT 116	C50(1.11); C58(1.12)	LDD0656	[8]
LDCM0340	AC75	HCT 116	C50(1.02); C58(1.08)	LDD0657	[8]
LDCM0341	AC76	HCT 116	C50(1.08); C58(1.12)	LDD0658	[8]
LDCM0342	AC77	HCT 116	C58(0.99); C50(1.01)	LDD0659	[8]
LDCM0343	AC78	HCT 116	C58(0.86); C50(0.96)	LDD0660	[8]
LDCM0344	AC79	HCT 116	C58(0.99); C50(1.04)	LDD0661	[8]
LDCM0345	AC8	HCT 116	C50(0.93); C58(1.15)	LDD0662	[8]
LDCM0346	AC80	HCT 116	C50(1.02); C58(1.12)	LDD0663	[8]
LDCM0347	AC81	HCT 116	C58(1.11); C50(1.21)	LDD0664	[8]
LDCM0348	AC82	HCT 116	C50(1.08); C58(1.13)	LDD0665	[8]
LDCM0349	AC83	HCT 116	C50(0.88); C58(1.39)	LDD0666	[8]
LDCM0350	AC84	HCT 116	C50(0.89); C58(1.13)	LDD0667	[8]
LDCM0351	AC85	HCT 116	C50(0.90); C58(1.10)	LDD0668	[8]
LDCM0352	AC86	HCT 116	C50(0.99); C58(1.16)	LDD0669	[8]
LDCM0353	AC87	HCT 116	C50(0.93); C58(1.21)	LDD0670	[8]
LDCM0354	AC88	HCT 116	C50(0.96); C58(1.32)	LDD0671	[8]
LDCM0355	AC89	HCT 116	C50(0.84); C58(1.24)	LDD0672	[8]
LDCM0357	AC90	HCT 116	C50(1.06); C58(1.17)	LDD0674	[8]
LDCM0358	AC91	HCT 116	C50(0.93); C58(1.43)	LDD0675	[8]
LDCM0359	AC92	HCT 116	C50(0.86); C58(1.21)	LDD0676	[8]
LDCM0360	AC93	HCT 116	C50(0.82); C58(1.14)	LDD0677	[8]
LDCM0361	AC94	HCT 116	C50(0.81); C58(1.20)	LDD0678	[8]
LDCM0362	AC95	HCT 116	C50(0.82); C58(1.17)	LDD0679	[8]
LDCM0363	AC96	HCT 116	C50(0.79); C58(1.45)	LDD0680	[8]
LDCM0364	AC97	HCT 116	C50(0.90); C58(1.37)	LDD0681	[8]
LDCM0365	AC98	HCT 116	C50(0.67); C58(0.89)	LDD0682	[8]
LDCM0366	AC99	HCT 116	C50(0.70); C58(0.73)	LDD0683	[8]
LDCM0248	AKOS034007472	HCT 116	C50(0.92); C58(1.11)	LDD0565	[8]
LDCM0356	AKOS034007680	HCT 116	C50(0.89); C58(1.25)	LDD0673	[8]
LDCM0275	AKOS034007705	HCT 116	C50(0.87); C58(1.29)	LDD0592	[8]
LDCM0020	ARS-1620	HCC44	C58(1.07); C50(1.08)	LDD2171	[8]
LDCM0108	Chloroacetamide	HeLa	N.A.	LDD0222	[14]
LDCM0367	CL1	HCT 116	C50(1.74); C58(1.92)	LDD0684	[8]
LDCM0368	CL10	HCT 116	C50(1.34); C58(1.75)	LDD0685	[8]
LDCM0369	CL100	HCT 116	C50(1.23); C58(1.24)	LDD0686	[8]
LDCM0370	CL101	HCT 116	C50(0.96); C58(1.37)	LDD0687	[8]
LDCM0371	CL102	HCT 116	C50(1.33); C58(1.82)	LDD0688	[8]
LDCM0372	CL103	HCT 116	C50(1.21); C58(1.46)	LDD0689	[8]
LDCM0373	CL104	HCT 116	C50(0.98); C58(1.29)	LDD0690	[8]
LDCM0374	CL105	HCT 116	C50(1.04); C58(1.15)	LDD0691	[8]
LDCM0375	CL106	HCT 116	C50(1.16); C58(1.24)	LDD0692	[8]
LDCM0376	CL107	HCT 116	C50(1.06); C58(1.16)	LDD0693	[8]
LDCM0377	CL108	HCT 116	C50(1.04); C58(1.33)	LDD0694	[8]
LDCM0378	CL109	HCT 116	C58(1.10); C50(1.12)	LDD0695	[8]
LDCM0379	CL11	HCT 116	C50(1.50); C58(1.78)	LDD0696	[8]
LDCM0380	CL110	HCT 116	C50(1.03); C58(1.08)	LDD0697	[8]
LDCM0381	CL111	HCT 116	C50(1.35); C58(1.43)	LDD0698	[8]
LDCM0382	CL112	HCT 116	C50(0.93); C58(1.50)	LDD0699	[8]
LDCM0383	CL113	HCT 116	C50(0.85); C58(1.08)	LDD0700	[8]
LDCM0384	CL114	HCT 116	C50(1.01); C58(1.74)	LDD0701	[8]
LDCM0385	CL115	HCT 116	C50(0.87); C58(1.30)	LDD0702	[8]
LDCM0386	CL116	HCT 116	C50(0.86); C58(1.02)	LDD0703	[8]
LDCM0387	CL117	HCT 116	C58(0.97); C50(1.56)	LDD0704	[8]
LDCM0388	CL118	HCT 116	C58(1.07); C50(1.16)	LDD0705	[8]
LDCM0389	CL119	HCT 116	C50(1.01); C58(1.03)	LDD0706	[8]
LDCM0390	CL12	HCT 116	C50(1.12); C58(1.46)	LDD0707	[8]
LDCM0391	CL120	HCT 116	C50(1.04); C58(1.23)	LDD0708	[8]
LDCM0392	CL121	HCT 116	C50(1.01); C58(1.09)	LDD0709	[8]
LDCM0393	CL122	HCT 116	C50(1.34); C58(1.80)	LDD0710	[8]
LDCM0394	CL123	HCT 116	C50(1.39); C58(1.42)	LDD0711	[8]
LDCM0395	CL124	HCT 116	C58(1.15); C50(1.21)	LDD0712	[8]
LDCM0396	CL125	HCT 116	C58(1.15); C50(1.19)	LDD0713	[8]
LDCM0397	CL126	HCT 116	C50(1.66); C58(2.63)	LDD0714	[8]
LDCM0398	CL127	HCT 116	C50(1.11); C58(1.24)	LDD0715	[8]
LDCM0399	CL128	HCT 116	C50(1.03); C58(1.14)	LDD0716	[8]
LDCM0400	CL13	HCT 116	C50(0.98); C58(1.30)	LDD0717	[8]
LDCM0401	CL14	HCT 116	C50(1.43); C58(1.72)	LDD0718	[8]
LDCM0402	CL15	HCT 116	C50(1.28); C58(2.32)	LDD0719	[8]
LDCM0403	CL16	HCT 116	C50(0.93); C58(0.93)	LDD0720	[8]
LDCM0404	CL17	HCT 116	C58(1.04); C50(1.30)	LDD0721	[8]
LDCM0405	CL18	HCT 116	C50(0.83); C58(0.88)	LDD0722	[8]
LDCM0406	CL19	HCT 116	C50(1.10); C58(1.21)	LDD0723	[8]
LDCM0407	CL2	HCT 116	C50(1.39); C58(1.42)	LDD0724	[8]
LDCM0408	CL20	HCT 116	C50(0.80); C58(1.00)	LDD0725	[8]
LDCM0409	CL21	HCT 116	C50(1.09); C58(1.17)	LDD0726	[8]
LDCM0410	CL22	HCT 116	C50(1.31); C58(1.38)	LDD0727	[8]
LDCM0411	CL23	HCT 116	C50(0.84); C58(0.93)	LDD0728	[8]
LDCM0412	CL24	HCT 116	C50(0.87); C58(1.06)	LDD0729	[8]
LDCM0413	CL25	HCT 116	C50(1.36); C58(1.27)	LDD0730	[8]
LDCM0414	CL26	HCT 116	C50(1.40); C58(1.39)	LDD0731	[8]
LDCM0415	CL27	HCT 116	C50(0.91); C58(1.17)	LDD0732	[8]
LDCM0416	CL28	HCT 116	C50(1.08); C58(1.17)	LDD0733	[8]
LDCM0417	CL29	HCT 116	C50(0.78); C58(1.10)	LDD0734	[8]
LDCM0418	CL3	HCT 116	C50(1.37); C58(1.38)	LDD0735	[8]
LDCM0419	CL30	HCT 116	C50(0.87); C58(1.05)	LDD0736	[8]
LDCM0420	CL31	HCT 116	C50(1.04); C58(0.98)	LDD0737	[8]
LDCM0421	CL32	HCT 116	C50(0.94); C58(1.00)	LDD0738	[8]
LDCM0422	CL33	HCT 116	C50(1.10); C58(2.04)	LDD0739	[8]
LDCM0423	CL34	HCT 116	C50(1.05); C58(1.46)	LDD0740	[8]
LDCM0424	CL35	HCT 116	C50(0.79); C58(1.00)	LDD0741	[8]
LDCM0425	CL36	HCT 116	C50(1.12); C58(1.48)	LDD0742	[8]
LDCM0426	CL37	HCT 116	C50(0.96); C58(1.42)	LDD0743	[8]
LDCM0428	CL39	HCT 116	C50(1.09); C58(1.19)	LDD0745	[8]
LDCM0429	CL4	HCT 116	C50(1.54); C58(2.99)	LDD0746	[8]
LDCM0430	CL40	HCT 116	C50(1.00); C58(1.50)	LDD0747	[8]
LDCM0431	CL41	HCT 116	C50(0.79); C58(1.10)	LDD0748	[8]
LDCM0432	CL42	HCT 116	C50(1.05); C58(1.05)	LDD0749	[8]
LDCM0433	CL43	HCT 116	C50(0.90); C58(1.08)	LDD0750	[8]
LDCM0434	CL44	HCT 116	C50(0.96); C58(1.15)	LDD0751	[8]
LDCM0435	CL45	HCT 116	C50(0.94); C58(1.04)	LDD0752	[8]
LDCM0436	CL46	HCT 116	C50(1.36); C58(1.78)	LDD0753	[8]
LDCM0437	CL47	HCT 116	C50(1.22); C58(1.26)	LDD0754	[8]
LDCM0438	CL48	HCT 116	C50(1.08); C58(1.47)	LDD0755	[8]
LDCM0439	CL49	HCT 116	C50(1.09); C58(1.23)	LDD0756	[8]
LDCM0440	CL5	HCT 116	C50(1.25); C58(1.36)	LDD0757	[8]
LDCM0441	CL50	HCT 116	C50(1.17); C58(1.30)	LDD0758	[8]
LDCM0442	CL51	HCT 116	C50(1.07); C58(1.42)	LDD0759	[8]
LDCM0443	CL52	HCT 116	C50(1.00); C58(1.34)	LDD0760	[8]
LDCM0444	CL53	HCT 116	C50(0.93); C58(1.13)	LDD0761	[8]
LDCM0445	CL54	HCT 116	C50(1.18); C58(1.34)	LDD0762	[8]
LDCM0446	CL55	HCT 116	C50(1.12); C58(1.34)	LDD0763	[8]
LDCM0447	CL56	HCT 116	C50(1.13); C58(1.11)	LDD0764	[8]
LDCM0448	CL57	HCT 116	C50(1.19); C58(1.36)	LDD0765	[8]
LDCM0449	CL58	HCT 116	C50(1.02); C58(1.41)	LDD0766	[8]
LDCM0450	CL59	HCT 116	C50(1.02); C58(1.06)	LDD0767	[8]
LDCM0451	CL6	HCT 116	C50(1.07); C58(1.19)	LDD0768	[8]
LDCM0452	CL60	HCT 116	C50(1.21); C58(1.34)	LDD0769	[8]
LDCM0453	CL61	HCT 116	C50(0.92); C58(1.06)	LDD0770	[8]
LDCM0454	CL62	HCT 116	C50(1.06); C58(1.18)	LDD0771	[8]
LDCM0455	CL63	HCT 116	C50(1.07); C58(1.63)	LDD0772	[8]
LDCM0456	CL64	HCT 116	C50(0.98); C58(1.28)	LDD0773	[8]
LDCM0457	CL65	HCT 116	C50(0.96); C58(1.21)	LDD0774	[8]
LDCM0458	CL66	HCT 116	C50(1.31); C58(2.75)	LDD0775	[8]
LDCM0459	CL67	HCT 116	C50(0.89); C58(1.21)	LDD0776	[8]
LDCM0460	CL68	HCT 116	C50(0.98); C58(1.42)	LDD0777	[8]
LDCM0461	CL69	HCT 116	C50(1.17); C58(1.54)	LDD0778	[8]
LDCM0462	CL7	HCT 116	C50(1.29); C58(1.33)	LDD0779	[8]
LDCM0463	CL70	HCT 116	C50(1.25); C58(1.50)	LDD0780	[8]
LDCM0464	CL71	HCT 116	C50(0.94); C58(1.21)	LDD0781	[8]
LDCM0465	CL72	HCT 116	C50(0.94); C58(0.90)	LDD0782	[8]
LDCM0466	CL73	HCT 116	C50(0.87); C58(0.87)	LDD0783	[8]
LDCM0467	CL74	HCT 116	C50(0.85); C58(1.00)	LDD0784	[8]
LDCM0469	CL76	HCT 116	C50(1.00); C58(1.46)	LDD0786	[8]
LDCM0470	CL77	HCT 116	C50(1.39); C58(1.28)	LDD0787	[8]
LDCM0471	CL78	HCT 116	C50(1.14); C58(1.45)	LDD0788	[8]
LDCM0472	CL79	HCT 116	C50(1.02); C58(1.06)	LDD0789	[8]
LDCM0473	CL8	HCT 116	C50(1.51); C58(1.82)	LDD0790	[8]
LDCM0474	CL80	HCT 116	C50(0.87); C58(1.13)	LDD0791	[8]
LDCM0475	CL81	HCT 116	C50(1.17); C58(1.24)	LDD0792	[8]
LDCM0476	CL82	HCT 116	C50(1.42); C58(2.04)	LDD0793	[8]
LDCM0477	CL83	HCT 116	C50(1.12); C58(1.31)	LDD0794	[8]
LDCM0478	CL84	HCT 116	C50(1.16); C58(1.31)	LDD0795	[8]
LDCM0479	CL85	HCT 116	C50(0.98); C58(1.06)	LDD0796	[8]
LDCM0480	CL86	HCT 116	C50(1.09); C58(1.00)	LDD0797	[8]
LDCM0481	CL87	HCT 116	C50(1.37); C58(2.00)	LDD0798	[8]
LDCM0482	CL88	HCT 116	C50(1.02); C58(1.08)	LDD0799	[8]
LDCM0483	CL89	HCT 116	C50(1.24); C58(1.66)	LDD0800	[8]
LDCM0484	CL9	HCT 116	C50(1.38); C58(2.16)	LDD0801	[8]
LDCM0485	CL90	HCT 116	C50(1.76); C58(2.17)	LDD0802	[8]
LDCM0486	CL91	HCT 116	C50(1.69); C58(1.73)	LDD0803	[8]
LDCM0487	CL92	HCT 116	C50(1.92); C58(1.71)	LDD0804	[8]
LDCM0488	CL93	HCT 116	C50(1.95); C58(1.64)	LDD0805	[8]
LDCM0489	CL94	HCT 116	C50(1.15); C58(1.57)	LDD0806	[8]
LDCM0490	CL95	HCT 116	C50(1.09); C58(1.35)	LDD0807	[8]
LDCM0491	CL96	HCT 116	C50(1.58); C58(1.52)	LDD0808	[8]
LDCM0492	CL97	HCT 116	C50(1.49); C58(2.01)	LDD0809	[8]
LDCM0493	CL98	HCT 116	C50(1.59); C58(1.81)	LDD0810	[8]
LDCM0494	CL99	HCT 116	C50(1.50); C58(1.56)	LDD0811	[8]
LDCM0495	E2913	HEK-293T	C58(1.09); C50(1.03); C23(1.08)	LDD1698	[18]
LDCM0625	F8	Ramos	C58(1.84); C50(1.26)	LDD2187	[19]
LDCM0572	Fragment10	Ramos	C58(5.18); C50(3.56)	LDD2189	[19]
LDCM0573	Fragment11	Ramos	C58(3.36); C50(0.14)	LDD2190	[19]
LDCM0574	Fragment12	Ramos	C58(8.10); C50(6.03)	LDD2191	[19]
LDCM0575	Fragment13	Ramos	C58(1.20); C50(0.87)	LDD2192	[19]
LDCM0576	Fragment14	Ramos	C58(6.84); C50(9.31)	LDD2193	[19]
LDCM0579	Fragment20	Ramos	C58(19.50)	LDD2194	[19]
LDCM0580	Fragment21	Ramos	C58(1.03); C50(1.16)	LDD2195	[19]
LDCM0582	Fragment23	Ramos	C58(0.87); C50(0.93)	LDD2196	[19]
LDCM0578	Fragment27	Ramos	C58(0.84); C50(0.91)	LDD2197	[19]
LDCM0586	Fragment28	Ramos	C58(1.24); C50(0.77)	LDD2198	[19]
LDCM0588	Fragment30	Ramos	C58(1.37); C50(1.32)	LDD2199	[19]
LDCM0589	Fragment31	Ramos	C58(1.78); C50(1.36)	LDD2200	[19]
LDCM0590	Fragment32	Ramos	C58(3.35); C50(3.16)	LDD2201	[19]
LDCM0468	Fragment33	HCT 116	C50(1.19); C58(1.82)	LDD0785	[8]
LDCM0596	Fragment38	Ramos	C58(4.41); C50(1.61)	LDD2203	[19]
LDCM0566	Fragment4	Ramos	C58(6.73); C50(4.24)	LDD2184	[19]
LDCM0427	Fragment51	HCT 116	C50(1.10); C58(1.14)	LDD0744	[8]
LDCM0610	Fragment52	Ramos	C58(1.90); C50(1.76)	LDD2204	[19]
LDCM0614	Fragment56	Ramos	C58(1.35); C50(1.02)	LDD2205	[19]
LDCM0569	Fragment7	Ramos	C58(5.55); C50(4.79)	LDD2186	[19]
LDCM0571	Fragment9	Ramos	C58(8.01)	LDD2188	[19]
LDCM0015	HNE	MDA-MB-231	C50(1.86)	LDD0346	[19]
LDCM0107	IAA	HeLa	N.A.	LDD0221	[14]
LDCM0179	JZ128	PC-3	N.A.	LDD0462	[3]
LDCM0022	KB02	HCT 116	C50(3.07)	LDD0080	[8]
LDCM0023	KB03	HCT 116	C50(1.37)	LDD0081	[8]
LDCM0024	KB05	HCT 116	C50(3.50)	LDD0082	[8]
LDCM0109	NEM	HeLa	N.A.	LDD0223	[14]
LDCM0521	Nucleophilic fragment 23b	MDA-MB-231	C58(1.15)	LDD2114	[4]
LDCM0628	OTUB2-COV-1	HEK-293T	C50(0.69)	LDD2207	[20]
LDCM0014	Panhematin	K562	3.01	LDD0063	[7]
LDCM0016	Ranjitkar_cp1	MDA-MB-231	2.00	LDD0123	[5]
LDCM0021	THZ1	HCT 116	C58(1.07); C50(1.08)	LDD2173	[8]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme

Click To Hide/Show 5 Protein(s) Interacting with This Target

Protein name	Family	Uniprot ID
Lipoprotein lipase (LPL)	Lipase family	P06858
rRNA methyltransferase 1, mitochondrial (MRM1)	RNA methyltransferase TrmH family	Q6IN84
Choline-phosphate cytidylyltransferase A (PCYT1A)	Cytidylyltransferase family	P49585
Probable glutathione peroxidase 8 (GPX8)	Glutathione peroxidase family	Q8TED1
Plasma kallikrein (KLKB1)	Peptidase S1 family	P03952

Transporter and channel

Click To Hide/Show 2 Protein(s) Interacting with This Target

Protein name				Family	Uniprot ID
Aquaporin-6 (AQP6)				MIP/aquaporin (TC 1.A.8) family	Q13520
Membrane-spanning 4-domains subfamily A member 3 (MS4A3)				MS4A family	Q96HJ5

Other

Click To Hide/Show 8 Protein(s) Interacting with This Target

Protein name	Family	Uniprot ID
Protein BRICK1 (BRK1)	BRK1 family	Q8WUW1
CDGSH iron-sulfur domain-containing protein 2 (CISD2)	CISD protein family	Q8N5K1
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3)	ERGIC family	Q9Y282
RAB6-interacting golgin (GORAB)	GORAB family	Q5T7V8
Translation initiation factor IF-3, mitochondrial (MTIF3)	IF-3 family	Q9H2K0
Angiotensinogen (AGT)	Serpin family	P01019
T-complex protein 1 subunit beta (CCT2)	TCP-1 chaperonin family	P78371
Transmembrane protein 80 (TMEM80)	.	Q96HE8

The Drug(s) Related To This Target

Approved

Click To Hide/Show 1 Drug(s) Interacting with This Target

Drug Name				Drug Type	External ID
Menadione				Small molecular drug	DB00170

References

1	Charting the Chemical Space of Acrylamide-Based Inhibitors of zDHHC20. ACS Med Chem Lett. 2022 Sep 26;13(10):1648-1654. doi: 10.1021/acsmedchemlett.2c00336. eCollection 2022 Oct 13.
2	A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10. Mass spectrometry data entry: PXD028270
3	A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification. J Am Chem Soc. 2019 Jan 9;141(1):191-203. doi: 10.1021/jacs.8b07911. Epub 2018 Dec 20.
4	Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29. Mass spectrometry data entry: PXD039908 , PXD029761
5	Appendage and Scaffold Diverse Fully Functionalized Small-Molecule Probes via a Minimalist Terminal Alkyne-Aliphatic Diazirine Isocyanide. J Org Chem. 2018 Sep 21;83(18):11245-11253. doi: 10.1021/acs.joc.8b01831. Epub 2018 Aug 31.
6	Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z. Mass spectrometry data entry: PXD044625
7	A Chemical Proteomic Map of Heme-Protein Interactions. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12. Mass spectrometry data entry: PXD034651
8	Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
9	Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23. Mass spectrometry data entry: PXD028853
10	Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24. Mass spectrometry data entry: PXD029255
11	A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21. Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
12	Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20. Mass spectrometry data entry: PXD022279
13	Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
14	ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
15	N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w. Mass spectrometry data entry: PXD041264
16	Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26. Mass spectrometry data entry: PXD041587
17	Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20. Mass spectrometry data entry: PXD007570
18	Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19. Mass spectrometry data entry: PXD044402
19	Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7. Mass spectrometry data entry: PXD027578
20	Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.

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Prof. Feng Zhu

Prof. Feng Ni