Details of the Probe

General Information of Probe

Probe ID
LDPC0339
Probe Name
C087
Synonyms
Z3433408107
Probe Type
PAL-AfBPP Probe
Structure
2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 390.4
Lipid-water partition coefficient (xlogp) 2
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C20H22N8O
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-6-(1,3-dimethylpyrazol-4-yl)-1-methylpyrazolo[3,4-b]pyridine-3-carboxamide
Canonical SMILES
CC1=NN(C=C1C2=NC3=C(C=C2)C(=NN3C)C(=O)NCCC4(N=N4)CCC#C)C
InChI
InChI=1S/C20H22N8O/c1-5-6-9-20(25-26-20)10-11-21-19(29)17-14-7-8-16(22-18(14)28(4)24-17)15-12-27(3)23-13(15)2/h1,7-8,12H,6,9-11H2,2-4H3,(H,21,29)
InChIKey
LVHGOMAIBKLKGF-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

116 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
5'-3' exonuclease PLD3 (PLD3) LDTP08476 35.26  LDD1779 
5'-nucleotidase domain-containing protein 2 (NT5DC2) LDTP18414 9.38  LDD1779 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 9.19  LDD1779 
Acid ceramidase (ASAH1) LDTP05905 11.00  LDD1779 
Adenosine 5'-monophosphoramidase HINT3 (HINT3) LDTP12415 12.30  LDD1779 
Adenosine deaminase (ADA) LDTP01803 29.65  LDD1779 
Adenosine kinase (ADK) LDTP04689 8.17  LDD1779 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 10.56  LDD1779 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 16.11  LDD1779 
Arginyl-tRNA--protein transferase 1 (ATE1) LDTP14534 8.22  LDD1779 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 7.67  LDD1779 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 10.34  LDD1779 
Beta-galactosidase (GLB1) LDTP02837 8.11  LDD1779 
Beta-glucuronidase (GUSB) LDTP02260 11.79  LDD1779 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 8.82  LDD1779 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 22.16  LDD1779 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 27.67  LDD1779 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 11.24  LDD1779 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 7.84  LDD1779 
Ceramide synthase 2 (CERS2) LDTP10329 9.25  LDD1779 
Choline kinase alpha (CHKA) LDTP03787 10.85  LDD1779 
Cyclin-dependent kinase 9 (CDK9) LDTP04384 9.32  LDD1779 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 14.12  LDD1779 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 19.29  LDD1779 
Cytochrome b5 type B (CYB5B) LDTP00697 11.63  LDD1779 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 10.20  LDD1779 
Dehydrogenase/reductase SDR family member 1 (DHRS1) LDTP10550 14.62  LDD1779 
Delta(24)-sterol reductase (DHCR24) LDTP06375 8.75  LDD1779 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 7.84  LDD1779 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 7.52  LDD1779 
Deoxyhypusine synthase (DHPS) LDTP04248 7.11  LDD1779 
Dipeptidyl peptidase 1 (CTSC) LDTP04572 11.00  LDD1779 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 18.25  LDD1779 
E3 ubiquitin-protein ligase LRSAM1 (LRSAM1) LDTP07672 6.96  LDD1779 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 7.01  LDD1779 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 10.34  LDD1779 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 24.59  LDD1779 
Exonuclease 1 (EXO1) LDTP13751 6.96  LDD1779 
FAD synthase (FLAD1) LDTP09200 7.46  LDD1779 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 8.51  LDD1779 
Flavin reductase (NADPH) (BLVRB) LDTP03511 10.34  LDD1779 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 9.51  LDD1779 
Glycogenin-1 (GYG1) LDTP04119 9.99  LDD1779 
Heme oxygenase 1 (HMOX1) LDTP02359 20.39  LDD1779 
Heme oxygenase 2 (HMOX2) LDTP03540 35.26  LDD1779 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 9.85  LDD1779 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 7.62  LDD1779 
Inositol 1,4,5-trisphosphate receptor-interacting protein (ITPRIP) LDTP08532 7.01  LDD1779 
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) LDTP04211 8.34  LDD1779 
Ketosamine-3-kinase (FN3KRP) LDTP16025 7.06  LDD1779 
Kinesin-like protein KIF14 (KIF14) LDTP06303 7.06  LDD1779 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 11.24  LDD1779 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 14.03  LDD1779 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 21.41  LDD1779 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 12.38  LDD1779 
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) LDTP03858 7.67  LDD1779 
Lysosomal alpha-glucosidase (GAA) LDTP02486 11.31  LDD1779 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 14.72  LDD1779 
Lysosomal protective protein (CTSA) LDTP02505 8.69  LDD1779 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 31.34  LDD1779 
Macrophage migration inhibitory factor (MIF) LDTP02713 8.40  LDD1779 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 6.92  LDD1779 
Minor histocompatibility antigen H13 (HM13) LDTP09396 13.74  LDD1779 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 8.22  LDD1779 
Myosin-10 (MYH10) LDTP03765 7.73  LDD1779 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 12.21  LDD1779 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 17.63  LDD1779 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 28.44  LDD1779 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 10.78  LDD1779 
Oligoribonuclease, mitochondrial (REXO2) LDTP13972 11.00  LDD1779 
Oxidized purine nucleoside triphosphate hydrolase (NUDT1) LDTP03816 7.16  LDD1779 
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (CPOX) LDTP03813 17.27  LDD1779 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 38.59  LDD1779 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 8.00  LDD1779 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 15.14  LDD1779 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 11.63  LDD1779 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 10.56  LDD1779 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 9.65  LDD1779 
Phospholipase A2 group XV (PLA2G15) LDTP09088 7.06  LDD1779 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 14.72  LDD1779 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 13.64  LDD1779 
Presequence protease, mitochondrial (PITRM1) LDTP07003 7.52  LDD1779 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 7.16  LDD1779 
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 8.34  LDD1779 
Prolyl endopeptidase-like (PREPL) LDTP06849 11.79  LDD1779 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 7.16  LDD1779 
Prostaglandin reductase 3 (PTGR3) LDTP15422 12.64  LDD1779 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 29.24  LDD1779 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 32.45  LDD1779 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 12.64  LDD1779 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 14.83  LDD1779 
Proteasome subunit beta type-7 (PSMB7) LDTP10862 7.67  LDD1779 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 15.67  LDD1779 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 12.47  LDD1779 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 22.16  LDD1779 
Rab-like protein 3 (RABL3) LDTP06986 7.11  LDD1779 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 10.56  LDD1779 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 10.56  LDD1779 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 53.82  LDD1779 
Ribonuclease T2 (RNASET2) LDTP00316 8.34  LDD1779 
S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) LDTP00890 7.84  LDD1779 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 30.70  LDD1779 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 8.69  LDD1779 
Serine protease HTRA2, mitochondrial (HTRA2) LDTP00773 7.01  LDD1779 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 21.41  LDD1779 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 12.47  LDD1779 
Squalene synthase (FDFT1) LDTP03842 14.12  LDD1779 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 8.28  LDD1779 
Tissue alpha-L-fucosidase (FUCA1) LDTP02006 7.16  LDD1779 
Transmembrane protein with metallophosphoesterase domain (TMPPE) LDTP07831 8.51  LDD1779 
Trimethyllysine dioxygenase, mitochondrial (TMLHE) LDTP12679 10.70  LDD1779 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 9.32  LDD1779 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 7.57  LDD1779 
V-type proton ATPase subunit D (ATP6V1D) LDTP14132 7.62  LDD1779 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 15.67  LDD1779 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 7.52  LDD1779 
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⏷ Show the Full List of 116 Enzyme
65 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 21.26  LDD1779 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 11.96  LDD1779 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 9.65  LDD1779 
ATP synthase subunit a (MT-ATP6) LDTP01804 11.24  LDD1779 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 14.12  LDD1779 
B-cell receptor-associated protein 29 (BCAP29) LDTP16201 47.84  LDD1779 
B-cell receptor-associated protein 31 (BCAP31) LDTP04426 13.45  LDD1779 
BRI3-binding protein (BRI3BP) LDTP15648 7.46  LDD1779 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 17.39  LDD1779 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 7.57  LDD1779 
Derlin-1 (DERL1) LDTP11245 8.00  LDD1779 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 50.56  LDD1779 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 9.85  LDD1779 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 11.71  LDD1779 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 6.92  LDD1779 
Lysosome membrane protein 2 (SCARB2) LDTP06034 18.38  LDD1779 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 9.85  LDD1779 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 8.22  LDD1779 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 12.30  LDD1779 
Metaxin-1 (MTX1) LDTP05900 8.17  LDD1779 
Metaxin-2 (MTX2) LDTP01217 8.34  LDD1779 
MICOS complex subunit MIC60 (IMMT) LDTP06660 7.36  LDD1779 
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) LDTP07439 8.11  LDD1779 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 9.19  LDD1779 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 11.47  LDD1779 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 42.81  LDD1779 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 25.11  LDD1779 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 9.58  LDD1779 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 12.64  LDD1779 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 18.90  LDD1779 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 7.62  LDD1779 
Mpv17-like protein 2 (MPV17L2) LDTP14952 16.80  LDD1779 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 8.34  LDD1779 
Nucleoporin Nup37 (NUP37) LDTP09203 14.32  LDD1779 
Occludin (OCLN) LDTP06581 7.36  LDD1779 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 10.41  LDD1779 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 9.58  LDD1779 
Peroxisomal membrane protein PMP34 (SLC25A17) LDTP00872 9.19  LDD1779 
Prosaposin (PSAP) LDTP02215 30.70  LDD1779 
Protein FAM8A1 (FAM8A1) LDTP16190 8.17  LDD1779 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 10.06  LDD1779 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 9.13  LDD1779 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 9.99  LDD1779 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 20.97  LDD1779 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 39.67  LDD1779 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 14.32  LDD1779 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 8.94  LDD1779 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 7.36  LDD1779 
Surfeit locus protein 4 (SURF4) LDTP00592 12.64  LDD1779 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 9.38  LDD1779 
Tetraspanin-10 (TSPAN10) LDTP15967 16.11  LDD1779 
Tetraspanin-3 (TSPAN3) LDTP16813 9.92  LDD1779 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 9.19  LDD1779 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 15.35  LDD1779 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 8.63  LDD1779 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 7.16  LDD1779 
Transmembrane protein 126A (TMEM126A) LDTP15948 18.90  LDD1779 
Transmembrane protein 160 (TMEM160) LDTP20002 13.27  LDD1779 
Transmembrane protein 199 (TMEM199) LDTP08881 20.82  LDD1779 
Transmembrane protein 205 (TMEM205) LDTP07667 10.70  LDD1779 
Transmembrane protein 87A (TMEM87A) LDTP15481 20.39  LDD1779 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 10.13  LDD1779 
Vang-like protein 1 (VANGL1) LDTP09288 7.21  LDD1779 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 15.03  LDD1779 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 10.20  LDD1779 
------------------------------------------------------------------------------------
⏷ Show the Full List of 65 Transporter and channel
3 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 9.19  LDD1779 
Paraspeckle component 1 (PSPC1) LDTP09694 7.16  LDD1779 
Y-box-binding protein 1 (YBX1) LDTP05065 18.77  LDD1779 
------------------------------------------------------------------------------------
111 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Alpha-actinin-4 (ACTN4) LDTP00843 7.46  LDD1779 
Alpha-internexin (INA) LDTP06527 12.91  LDD1779 
Apolipoprotein L2 (APOL2) LDTP11076 51.63  LDD1779 
Arfaptin-2 (ARFIP2) LDTP04557 6.96  LDD1779 
BTB/POZ domain-containing protein KCTD12 (KCTD12) LDTP15705 7.84  LDD1779 
Calumenin (CALU) LDTP00887 21.41  LDD1779 
Centrin-2 (CETN2) LDTP03926 8.06  LDD1779 
Centrosomal protein 43 (CEP43) LDTP01652 10.06  LDD1779 
Centrosomal protein of 55 kDa (CEP55) LDTP06886 7.36  LDD1779 
Clustered mitochondria protein homolog (CLUH) LDTP14486 9.65  LDD1779 
Coiled-coil domain-containing protein 6 (CCDC6) LDTP06515 9.13  LDD1779 
Cold-inducible RNA-binding protein (CIRBP) LDTP06022 13.00  LDD1779 
Collectin-12 (COLEC12) LDTP07031 7.78  LDD1779 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 27.28  LDD1779 
DDRGK domain-containing protein 1 (DDRGK1) LDTP10403 8.22  LDD1779 
Dedicator of cytokinesis protein 1 (DOCK1) LDTP06072 7.41  LDD1779 
Dynactin subunit 3 (DCTN3) LDTP01359 7.26  LDD1779 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 14.42  LDD1779 
Early endosome antigen 1 (EEA1) LDTP06310 6.92  LDD1779 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 13.27  LDD1779 
Emerin (EMD) LDTP04356 7.52  LDD1779 
Endothelial differentiation-related factor 1 (EDF1) LDTP01067 8.75  LDD1779 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 39.67  LDD1779 
Eukaryotic translation initiation factor 4B (EIF4B) LDTP03247 7.16  LDD1779 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 10.41  LDD1779 
Galectin-3-binding protein (LGALS3BP) LDTP05558 7.78  LDD1779 
Ganglioside GM2 activator (GM2A) LDTP02927 7.11  LDD1779 
Golgi apparatus protein 1 (GLG1) LDTP09920 16.22  LDD1779 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 17.03  LDD1779 
Golgin subfamily A member 3 (GOLGA3) LDTP05556 9.06  LDD1779 
Growth factor receptor-bound protein 2 (GRB2) LDTP05035 7.46  LDD1779 
HAUS augmin-like complex subunit 1 (HAUS1) LDTP10184 9.45  LDD1779 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 9.71  LDD1779 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 8.00  LDD1779 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 8.17  LDD1779 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 8.63  LDD1779 
Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 7.31  LDD1779 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 7.36  LDD1779 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 8.94  LDD1779 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 7.06  LDD1779 
Hyaluronan mediated motility receptor (HMMR) LDTP01177 6.92  LDD1779 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 9.25  LDD1779 
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) LDTP14272 8.82  LDD1779 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 33.36  LDD1779 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 7.89  LDD1779 
Kinectin (KTN1) LDTP08238 6.92  LDD1779 
Kinetochore protein NDC80 homolog (NDC80) LDTP00431 6.92  LDD1779 
Kinetochore protein Nuf2 (NUF2) LDTP11525 8.57  LDD1779 
Kinetochore protein Spc24 (SPC24) LDTP09069 22.47  LDD1779 
Lamin-B2 (LMNB2) LDTP05400 7.06  LDD1779 
Large proline-rich protein BAG6 (BAG6) LDTP04094 9.99  LDD1779 
Large ribosomal subunit protein mL40 (MRPL40) LDTP12395 11.31  LDD1779 
MAGUK p55 subfamily member 2 (MPP2) LDTP06068 9.38  LDD1779 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 23.26  LDD1779 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 8.63  LDD1779 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 25.63  LDD1779 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 9.19  LDD1779 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 39.12  LDD1779 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 17.63  LDD1779 
Nestin (NES) LDTP04206 7.94  LDD1779 
Neudesin (NENF) LDTP13630 12.38  LDD1779 
Neurofilament light polypeptide (NEFL) LDTP02180 18.64  LDD1779 
Neurofilament medium polypeptide (NEFM) LDTP02181 20.25  LDD1779 
NSFL1 cofactor p47 (NSFL1C) LDTP13684 7.26  LDD1779 
Nucleobindin-1 (NUCB1) LDTP05375 11.63  LDD1779 
Nucleobindin-2 (NUCB2) LDTP05160 17.88  LDD1779 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 8.82  LDD1779 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 9.51  LDD1779 
Nurim (NRM) LDTP08606 11.16  LDD1779 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 14.12  LDD1779 
Optic atrophy 3 protein (OPA3) LDTP16006 7.94  LDD1779 
Phosducin-like protein 3 (PDCL3) LDTP11825 27.47  LDD1779 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 7.67  LDD1779 
Prefoldin subunit 2 (PFDN2) LDTP13309 12.64  LDD1779 
Prelamin-A/C (LMNA) LDTP01932 13.74  LDD1779 
Programmed cell death protein 5 (PDCD5) LDTP00417 13.18  LDD1779 
Protein bicaudal D homolog 2 (BICD2) LDTP09410 9.00  LDD1779 
Protein CEBPZOS (CEBPZOS) LDTP18883 9.25  LDD1779 
Protein FAM114A2 (FAM114A2) LDTP16080 10.06  LDD1779 
Protein FAM162A (FAM162A) LDTP10056 13.09  LDD1779 
Protein PALS2 (PALS2) LDTP16156 7.78  LDD1779 
Protein PBDC1 (PBDC1) LDTP19924 7.67  LDD1779 
Protein SET (SET) LDTP05277 14.32  LDD1779 
Protein unc-119 homolog B (UNC119B) LDTP00105 23.59  LDD1779 
Protein YIF1A (YIF1A) LDTP01494 7.73  LDD1779 
Reticulocalbin-1 (RCN1) LDTP06352 8.11  LDD1779 
Reticulocalbin-2 (RCN2) LDTP06097 21.26  LDD1779 
RNA-binding motif protein, X chromosome (RBMX) LDTP03850 9.32  LDD1779 
RNA-binding protein EWS (EWSR1) LDTP05318 8.34  LDD1779 
RNA-binding protein FUS (FUS) LDTP03775 9.78  LDD1779 
Serine/arginine-rich splicing factor 2 (SRSF2) LDTP05280 7.84  LDD1779 
Single-stranded DNA-binding protein, mitochondrial (SSBP1) LDTP05437 8.94  LDD1779 
Small ribosomal subunit protein eS10 (RPS10) LDTP04111 7.46  LDD1779 
Syntaxin-18 (STX18) LDTP13086 8.34  LDD1779 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 9.06  LDD1779 
Tetraspanin-6 (TSPAN6) LDTP14458 11.24  LDD1779 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 12.38  LDD1779 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 8.34  LDD1779 
Thyroid receptor-interacting protein 11 (TRIP11) LDTP06431 11.31  LDD1779 
TIP41-like protein (TIPRL) LDTP01285 7.62  LDD1779 
TraB domain-containing protein (TRABD) LDTP19963 12.47  LDD1779 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 8.06  LDD1779 
Trophoblast glycoprotein (TPBG) LDTP05960 7.36  LDD1779 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 7.73  LDD1779 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 12.55  LDD1779 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 18.51  LDD1779 
Ubiquitin-associated domain-containing protein 1 (UBAC1) LDTP11164 8.82  LDD1779 
Ubiquitin-associated protein 2-like (UBAP2L) LDTP06060 7.46  LDD1779 
UV excision repair protein RAD23 homolog A (RAD23A) LDTP04626 13.18  LDD1779 
Vimentin (VIM) LDTP02297 27.28  LDD1779 
Zinc finger CCHC domain-containing protein 3 (ZCCHC3) LDTP12623 7.89  LDD1779 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1779 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587