Details of the Target

General Information of Target

Target ID LDTP04207
Target Name Heat shock 70 kDa protein 13 (HSPA13)
Gene Name HSPA13
Gene ID 6782
Synonyms
STCH; Heat shock 70 kDa protein 13; Microsomal stress-70 protein ATPase core; Stress-70 protein chaperone microsome-associated 60 kDa protein
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAREMTILGSAVLTLLLAGYLAQQYLPLPTPKVIGIDLGTTYCSVGVFFPGTGKVKVIPD
ENGHISIPSMVSFTDNDVYVGYESVELADSNPQNTIYDAKRFIGKIFTAEELEAEIGRYP
FKVLNKNGMVEFSVTSNETITVSPEYVGSRLLLKLKEMAEAYLGMPVANAVISVPAEFDL
KQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHKADVFHVLVIDLGGGTLDVSLLNKQG
GMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTYGFVPSRKEEIHRLRQAVEMVKLNLT
LHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVL
FETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQE
FFGKDPNTSVDPDLAVVTGVAIQAGIDGGSWPLQVSALEIPNKHLQKTNFN
Target Bioclass
Other
Family
Heat shock protein 70 family
Subcellular location
Microsome
Function Has peptide-independent ATPase activity.
Uniprot ID
P48723
Ensemble ID
ENST00000285667.4
HGNC ID
HGNC:11375

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
FBPP2
 Probe Info  		3.24  LDD0318  [1]
DBIA
 Probe Info  		C43(1.77)  LDD3365  [2]
5E-2FA
 Probe Info  		N.A.  LDD2235  [3]
m-APA
 Probe Info  		H322(0.00); H339(0.00)  LDD2231  [3]
PAL-AfBPP Probe
Click To Hide/Show 37 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C022
 Probe Info  		7.46  LDD1728  [4]
C040
 Probe Info  		11.96  LDD1740  [4]
C041
 Probe Info  		5.66  LDD1741  [4]
C056
 Probe Info  		20.39  LDD1753  [4]
C070
 Probe Info  		8.69  LDD1766  [4]
C086
 Probe Info  		6.45  LDD1778  [4]
C087
 Probe Info  		8.17  LDD1779  [4]
C091
 Probe Info  		11.47  LDD1782  [4]
C092
 Probe Info  		17.51  LDD1783  [4]
C100
 Probe Info  		5.50  LDD1789  [4]
C106
 Probe Info  		21.26  LDD1793  [4]
C107
 Probe Info  		5.78  LDD1794  [4]
C108
 Probe Info  		7.89  LDD1795  [4]
C134
 Probe Info  		21.71  LDD1816  [4]
C160
 Probe Info  		8.00  LDD1840  [4]
C161
 Probe Info  		12.30  LDD1841  [4]
C170
 Probe Info  		8.75  LDD1850  [4]
C186
 Probe Info  		8.06  LDD1864  [4]
C201
 Probe Info  		25.11  LDD1877  [4]
C289
 Probe Info  		37.27  LDD1959  [4]
C293
 Probe Info  		16.91  LDD1963  [4]
C310
 Probe Info  		11.88  LDD1977  [4]
C314
 Probe Info  		11.63  LDD1981  [4]
C338
 Probe Info  		10.48  LDD2001  [4]
C349
 Probe Info  		8.94  LDD2010  [4]
C350
 Probe Info  		24.08  LDD2011  [4]
C355
 Probe Info  		23.26  LDD2016  [4]
C362
 Probe Info  		36.50  LDD2023  [4]
C382
 Probe Info  		8.88  LDD2041  [4]
C390
 Probe Info  		43.11  LDD2049  [4]
C403
 Probe Info  		16.11  LDD2061  [4]
C407
 Probe Info  		18.38  LDD2064  [4]
C413
 Probe Info  		12.47  LDD2069  [4]
C425
 Probe Info  		6.19  LDD2080  [4]
C429
 Probe Info  		11.16  LDD2084  [4]
C431
 Probe Info  		21.71  LDD2086  [4]
OEA-DA
 Probe Info  		20.00  LDD0046  [5]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 PaTu 8988t C43(0.44)  LDD1093  [6]
 LDCM0215  AC10 PaTu 8988t C43(0.51)  LDD1094  [6]
 LDCM0226  AC11 PaTu 8988t C43(0.55)  LDD1105  [6]
 LDCM0230  AC113 PaTu 8988t C43(1.46)  LDD1109  [6]
 LDCM0231  AC114 PaTu 8988t C43(1.33)  LDD1110  [6]
 LDCM0232  AC115 PaTu 8988t C43(0.93)  LDD1111  [6]
 LDCM0233  AC116 PaTu 8988t C43(0.66)  LDD1112  [6]
 LDCM0234  AC117 PaTu 8988t C43(1.01)  LDD1113  [6]
 LDCM0235  AC118 PaTu 8988t C43(1.06)  LDD1114  [6]
 LDCM0236  AC119 PaTu 8988t C43(0.50)  LDD1115  [6]
 LDCM0237  AC12 PaTu 8988t C43(0.50)  LDD1116  [6]
 LDCM0238  AC120 PaTu 8988t C43(0.64)  LDD1117  [6]
 LDCM0239  AC121 PaTu 8988t C43(0.46)  LDD1118  [6]
 LDCM0240  AC122 PaTu 8988t C43(1.10)  LDD1119  [6]
 LDCM0241  AC123 PaTu 8988t C43(0.93)  LDD1120  [6]
 LDCM0242  AC124 PaTu 8988t C43(0.37)  LDD1121  [6]
 LDCM0243  AC125 PaTu 8988t C43(0.73)  LDD1122  [6]
 LDCM0244  AC126 PaTu 8988t C43(0.94)  LDD1123  [6]
 LDCM0245  AC127 PaTu 8988t C43(0.43)  LDD1124  [6]
 LDCM0259  AC14 PaTu 8988t C43(0.98)  LDD1138  [6]
 LDCM0263  AC143 PaTu 8988t C43(0.69)  LDD1142  [6]
 LDCM0264  AC144 PaTu 8988t C43(0.62)  LDD1143  [6]
 LDCM0265  AC145 PaTu 8988t C43(0.77)  LDD1144  [6]
 LDCM0266  AC146 PaTu 8988t C43(0.83)  LDD1145  [6]
 LDCM0267  AC147 PaTu 8988t C43(0.99)  LDD1146  [6]
 LDCM0268  AC148 PaTu 8988t C43(0.43)  LDD1147  [6]
 LDCM0269  AC149 PaTu 8988t C43(0.30)  LDD1148  [6]
 LDCM0270  AC15 PaTu 8988t C43(0.67)  LDD1149  [6]
 LDCM0271  AC150 PaTu 8988t C43(0.24)  LDD1150  [6]
 LDCM0272  AC151 PaTu 8988t C43(0.29)  LDD1151  [6]
 LDCM0273  AC152 PaTu 8988t C43(0.27)  LDD1152  [6]
 LDCM0274  AC153 PaTu 8988t C43(0.25)  LDD1153  [6]
 LDCM0621  AC154 PaTu 8988t C43(0.33)  LDD2166  [6]
 LDCM0622  AC155 PaTu 8988t C43(0.28)  LDD2167  [6]
 LDCM0623  AC156 PaTu 8988t C43(0.49)  LDD2168  [6]
 LDCM0624  AC157 PaTu 8988t C43(0.26)  LDD2169  [6]
 LDCM0276  AC17 HEK-293T C43(0.75)  LDD1515  [7]
 LDCM0277  AC18 HEK-293T C43(0.82)  LDD1516  [7]
 LDCM0278  AC19 HEK-293T C43(0.86)  LDD1517  [7]
 LDCM0279  AC2 PaTu 8988t C43(0.52)  LDD1158  [6]
 LDCM0280  AC20 HEK-293T C43(1.00)  LDD1519  [7]
 LDCM0281  AC21 HEK-293T C43(0.95)  LDD1520  [7]
 LDCM0282  AC22 HEK-293T C43(0.81)  LDD1521  [7]
 LDCM0283  AC23 HEK-293T C43(1.09)  LDD1522  [7]
 LDCM0284  AC24 HEK-293T C43(0.91)  LDD1523  [7]
 LDCM0285  AC25 HEK-293T C43(0.82)  LDD1524  [7]
 LDCM0286  AC26 HEK-293T C43(1.06)  LDD1525  [7]
 LDCM0287  AC27 HEK-293T C43(0.94)  LDD1526  [7]
 LDCM0288  AC28 HEK-293T C43(0.92)  LDD1527  [7]
 LDCM0289  AC29 HEK-293T C43(0.98)  LDD1528  [7]
 LDCM0290  AC3 PaTu 8988t C43(0.65)  LDD1169  [6]
 LDCM0291  AC30 HEK-293T C43(0.91)  LDD1530  [7]
 LDCM0292  AC31 HEK-293T C43(1.04)  LDD1531  [7]
 LDCM0293  AC32 HEK-293T C43(1.01)  LDD1532  [7]
 LDCM0294  AC33 HEK-293T C43(0.79)  LDD1533  [7]
 LDCM0295  AC34 HEK-293T C43(1.13)  LDD1534  [7]
 LDCM0296  AC35 HEK-293T C43(0.98)  LDD1535  [7]
 LDCM0297  AC36 HEK-293T C43(0.88)  LDD1536  [7]
 LDCM0298  AC37 HEK-293T C43(0.96)  LDD1537  [7]
 LDCM0299  AC38 HEK-293T C43(0.96)  LDD1538  [7]
 LDCM0300  AC39 HEK-293T C43(0.99)  LDD1539  [7]
 LDCM0301  AC4 PaTu 8988t C43(0.85)  LDD1180  [6]
 LDCM0302  AC40 HEK-293T C43(1.11)  LDD1541  [7]
 LDCM0303  AC41 HEK-293T C43(0.93)  LDD1542  [7]
 LDCM0304  AC42 HEK-293T C43(1.14)  LDD1543  [7]
 LDCM0305  AC43 HEK-293T C43(0.92)  LDD1544  [7]
 LDCM0306  AC44 HEK-293T C43(0.86)  LDD1545  [7]
 LDCM0307  AC45 HEK-293T C43(1.02)  LDD1546  [7]
 LDCM0308  AC46 PaTu 8988t C43(0.80)  LDD1187  [6]
 LDCM0309  AC47 PaTu 8988t C43(1.04)  LDD1188  [6]
 LDCM0310  AC48 PaTu 8988t C43(0.55)  LDD1189  [6]
 LDCM0311  AC49 PaTu 8988t C43(0.33)  LDD1190  [6]
 LDCM0312  AC5 PaTu 8988t C43(0.41)  LDD1191  [6]
 LDCM0313  AC50 PaTu 8988t C43(0.36)  LDD1192  [6]
 LDCM0314  AC51 PaTu 8988t C43(0.28)  LDD1193  [6]
 LDCM0315  AC52 PaTu 8988t C43(0.46)  LDD1194  [6]
 LDCM0316  AC53 PaTu 8988t C43(0.36)  LDD1195  [6]
 LDCM0317  AC54 PaTu 8988t C43(0.32)  LDD1196  [6]
 LDCM0318  AC55 PaTu 8988t C43(0.92)  LDD1197  [6]
 LDCM0319  AC56 PaTu 8988t C43(0.57)  LDD1198  [6]
 LDCM0320  AC57 HEK-293T C43(0.84)  LDD1559  [7]
 LDCM0321  AC58 HEK-293T C43(1.01)  LDD1560  [7]
 LDCM0322  AC59 HEK-293T C43(0.85)  LDD1561  [7]
 LDCM0323  AC6 PaTu 8988t C43(0.94)  LDD1202  [6]
 LDCM0324  AC60 HEK-293T C43(0.87)  LDD1563  [7]
 LDCM0325  AC61 HEK-293T C43(0.95)  LDD1564  [7]
 LDCM0326  AC62 HEK-293T C43(0.94)  LDD1565  [7]
 LDCM0327  AC63 HEK-293T C43(1.01)  LDD1566  [7]
 LDCM0328  AC64 HEK-293T C43(1.05)  LDD1567  [7]
 LDCM0334  AC7 PaTu 8988t C43(0.79)  LDD1213  [6]
 LDCM0345  AC8 PaTu 8988t C43(0.96)  LDD1224  [6]
 LDCM0248  AKOS034007472 PaTu 8988t C43(1.20)  LDD1127  [6]
 LDCM0356  AKOS034007680 PaTu 8988t C43(0.50)  LDD1235  [6]
 LDCM0275  AKOS034007705 PaTu 8988t C43(0.47)  LDD1154  [6]
 LDCM0367  CL1 PaTu 8988t C43(0.77)  LDD1246  [6]
 LDCM0368  CL10 PaTu 8988t C43(0.33)  LDD1247  [6]
 LDCM0369  CL100 PaTu 8988t C43(0.80)  LDD1248  [6]
 LDCM0370  CL101 PaTu 8988t C43(0.63)  LDD1249  [6]
 LDCM0371  CL102 PaTu 8988t C43(0.49)  LDD1250  [6]
 LDCM0372  CL103 PaTu 8988t C43(0.55)  LDD1251  [6]
 LDCM0373  CL104 PaTu 8988t C43(0.63)  LDD1252  [6]
 LDCM0374  CL105 HEK-293T C43(2.02)  LDD1578  [7]
 LDCM0375  CL106 HEK-293T C43(1.08)  LDD1579  [7]
 LDCM0376  CL107 HEK-293T C43(0.93)  LDD1580  [7]
 LDCM0377  CL108 HEK-293T C43(1.29)  LDD1581  [7]
 LDCM0378  CL109 HEK-293T C43(0.95)  LDD1582  [7]
 LDCM0379  CL11 PaTu 8988t C43(0.76)  LDD1258  [6]
 LDCM0380  CL110 HEK-293T C43(1.07)  LDD1584  [7]
 LDCM0381  CL111 HEK-293T C43(1.02)  LDD1585  [7]
 LDCM0382  CL112 HEK-293T C43(0.94)  LDD1586  [7]
 LDCM0383  CL113 HEK-293T C43(1.41)  LDD1587  [7]
 LDCM0384  CL114 HEK-293T C43(0.92)  LDD1588  [7]
 LDCM0385  CL115 HEK-293T C43(1.03)  LDD1589  [7]
 LDCM0386  CL116 HEK-293T C43(0.99)  LDD1590  [7]
 LDCM0387  CL117 HEK-293T C43(0.97)  LDD1591  [7]
 LDCM0388  CL118 HEK-293T C43(1.01)  LDD1592  [7]
 LDCM0389  CL119 HEK-293T C43(1.00)  LDD1593  [7]
 LDCM0390  CL12 PaTu 8988t C43(0.45)  LDD1269  [6]
 LDCM0391  CL120 HEK-293T C43(1.11)  LDD1595  [7]
 LDCM0392  CL121 PaTu 8988t C43(0.74)  LDD1271  [6]
 LDCM0393  CL122 PaTu 8988t C43(0.73)  LDD1272  [6]
 LDCM0394  CL123 PaTu 8988t C43(0.49)  LDD1273  [6]
 LDCM0395  CL124 PaTu 8988t C43(0.31)  LDD1274  [6]
 LDCM0396  CL125 HEK-293T C43(0.98)  LDD1600  [7]
 LDCM0397  CL126 HEK-293T C43(1.00)  LDD1601  [7]
 LDCM0398  CL127 HEK-293T C43(0.93)  LDD1602  [7]
 LDCM0399  CL128 HEK-293T C43(0.95)  LDD1603  [7]
 LDCM0400  CL13 PaTu 8988t C43(0.36)  LDD1279  [6]
 LDCM0401  CL14 PaTu 8988t C43(0.41)  LDD1280  [6]
 LDCM0402  CL15 PaTu 8988t C43(0.37)  LDD1281  [6]
 LDCM0403  CL16 HEK-293T C43(1.03)  LDD1607  [7]
 LDCM0404  CL17 HEK-293T C43(0.73)  LDD1608  [7]
 LDCM0405  CL18 HEK-293T C43(1.01)  LDD1609  [7]
 LDCM0406  CL19 HEK-293T C43(0.90)  LDD1610  [7]
 LDCM0407  CL2 PaTu 8988t C43(0.57)  LDD1286  [6]
 LDCM0408  CL20 HEK-293T C43(0.90)  LDD1612  [7]
 LDCM0409  CL21 HEK-293T C43(0.92)  LDD1613  [7]
 LDCM0410  CL22 HEK-293T C43(0.93)  LDD1614  [7]
 LDCM0411  CL23 HEK-293T C43(1.07)  LDD1615  [7]
 LDCM0412  CL24 HEK-293T C43(1.10)  LDD1616  [7]
 LDCM0413  CL25 HEK-293T C43(0.78)  LDD1617  [7]
 LDCM0414  CL26 HEK-293T C43(1.09)  LDD1618  [7]
 LDCM0415  CL27 HEK-293T C43(0.96)  LDD1619  [7]
 LDCM0416  CL28 HEK-293T C43(0.97)  LDD1620  [7]
 LDCM0417  CL29 HEK-293T C43(0.76)  LDD1621  [7]
 LDCM0418  CL3 PaTu 8988t C43(0.59)  LDD1297  [6]
 LDCM0419  CL30 HEK-293T C43(1.05)  LDD1623  [7]
 LDCM0420  CL31 HEK-293T C43(1.02)  LDD1624  [7]
 LDCM0421  CL32 HEK-293T C43(0.97)  LDD1625  [7]
 LDCM0422  CL33 HEK-293T C43(0.92)  LDD1626  [7]
 LDCM0423  CL34 HEK-293T C43(0.93)  LDD1627  [7]
 LDCM0424  CL35 HEK-293T C43(1.10)  LDD1628  [7]
 LDCM0425  CL36 HEK-293T C43(1.09)  LDD1629  [7]
 LDCM0426  CL37 HEK-293T C43(1.11)  LDD1630  [7]
 LDCM0428  CL39 HEK-293T C43(0.94)  LDD1632  [7]
 LDCM0429  CL4 PaTu 8988t C43(0.88)  LDD1308  [6]
 LDCM0430  CL40 HEK-293T C43(0.83)  LDD1634  [7]
 LDCM0431  CL41 HEK-293T C43(0.82)  LDD1635  [7]
 LDCM0432  CL42 HEK-293T C43(1.00)  LDD1636  [7]
 LDCM0433  CL43 HEK-293T C43(1.25)  LDD1637  [7]
 LDCM0434  CL44 HEK-293T C43(0.99)  LDD1638  [7]
 LDCM0435  CL45 HEK-293T C43(0.91)  LDD1639  [7]
 LDCM0436  CL46 HEK-293T C43(0.93)  LDD1640  [7]
 LDCM0437  CL47 HEK-293T C43(1.05)  LDD1641  [7]
 LDCM0438  CL48 HEK-293T C43(0.96)  LDD1642  [7]
 LDCM0439  CL49 HEK-293T C43(1.22)  LDD1643  [7]
 LDCM0440  CL5 PaTu 8988t C43(0.35)  LDD1319  [6]
 LDCM0441  CL50 HEK-293T C43(1.12)  LDD1645  [7]
 LDCM0443  CL52 HEK-293T C43(0.87)  LDD1646  [7]
 LDCM0444  CL53 HEK-293T C43(0.77)  LDD1647  [7]
 LDCM0445  CL54 HEK-293T C43(0.90)  LDD1648  [7]
 LDCM0446  CL55 HEK-293T C43(0.90)  LDD1649  [7]
 LDCM0447  CL56 HEK-293T C43(0.94)  LDD1650  [7]
 LDCM0448  CL57 HEK-293T C43(0.85)  LDD1651  [7]
 LDCM0449  CL58 HEK-293T C43(0.87)  LDD1652  [7]
 LDCM0450  CL59 HEK-293T C43(1.01)  LDD1653  [7]
 LDCM0451  CL6 PaTu 8988t C43(0.34)  LDD1330  [6]
 LDCM0452  CL60 HEK-293T C43(1.00)  LDD1655  [7]
 LDCM0453  CL61 PaTu 8988t C43(1.18)  LDD1332  [6]
 LDCM0454  CL62 PaTu 8988t C43(1.52)  LDD1333  [6]
 LDCM0455  CL63 PaTu 8988t C43(1.46)  LDD1334  [6]
 LDCM0456  CL64 PaTu 8988t C43(0.87)  LDD1335  [6]
 LDCM0457  CL65 PaTu 8988t C43(0.80)  LDD1336  [6]
 LDCM0458  CL66 PaTu 8988t C43(0.97)  LDD1337  [6]
 LDCM0459  CL67 PaTu 8988t C43(0.52)  LDD1338  [6]
 LDCM0460  CL68 PaTu 8988t C43(0.57)  LDD1339  [6]
 LDCM0461  CL69 PaTu 8988t C43(0.53)  LDD1340  [6]
 LDCM0462  CL7 PaTu 8988t C43(0.30)  LDD1341  [6]
 LDCM0463  CL70 PaTu 8988t C43(0.54)  LDD1342  [6]
 LDCM0464  CL71 PaTu 8988t C43(1.56)  LDD1343  [6]
 LDCM0465  CL72 PaTu 8988t C43(2.47)  LDD1344  [6]
 LDCM0466  CL73 PaTu 8988t C43(0.59)  LDD1345  [6]
 LDCM0467  CL74 PaTu 8988t C43(1.40)  LDD1346  [6]
 LDCM0469  CL76 HEK-293T C43(1.19)  LDD1672  [7]
 LDCM0470  CL77 HEK-293T C43(0.82)  LDD1673  [7]
 LDCM0471  CL78 HEK-293T C43(0.94)  LDD1674  [7]
 LDCM0472  CL79 HEK-293T C43(0.99)  LDD1675  [7]
 LDCM0473  CL8 PaTu 8988t C43(0.32)  LDD1352  [6]
 LDCM0474  CL80 HEK-293T C43(0.80)  LDD1677  [7]
 LDCM0475  CL81 HEK-293T C43(0.88)  LDD1678  [7]
 LDCM0476  CL82 HEK-293T C43(1.02)  LDD1679  [7]
 LDCM0477  CL83 HEK-293T C43(1.04)  LDD1680  [7]
 LDCM0478  CL84 HEK-293T C43(1.09)  LDD1681  [7]
 LDCM0479  CL85 HEK-293T C43(1.01)  LDD1682  [7]
 LDCM0480  CL86 HEK-293T C43(1.13)  LDD1683  [7]
 LDCM0481  CL87 HEK-293T C43(0.96)  LDD1684  [7]
 LDCM0482  CL88 HEK-293T C43(0.90)  LDD1685  [7]
 LDCM0483  CL89 HEK-293T C43(0.89)  LDD1686  [7]
 LDCM0484  CL9 PaTu 8988t C43(0.31)  LDD1363  [6]
 LDCM0485  CL90 HEK-293T C43(0.95)  LDD1688  [7]
 LDCM0486  CL91 PaTu 8988t C43(0.95)  LDD1365  [6]
 LDCM0487  CL92 PaTu 8988t C43(0.53)  LDD1366  [6]
 LDCM0488  CL93 PaTu 8988t C43(0.52)  LDD1367  [6]
 LDCM0489  CL94 PaTu 8988t C43(0.76)  LDD1368  [6]
 LDCM0490  CL95 PaTu 8988t C43(0.44)  LDD1369  [6]
 LDCM0491  CL96 PaTu 8988t C43(1.09)  LDD1370  [6]
 LDCM0492  CL97 PaTu 8988t C43(0.52)  LDD1371  [6]
 LDCM0493  CL98 PaTu 8988t C43(0.46)  LDD1372  [6]
 LDCM0494  CL99 PaTu 8988t C43(0.54)  LDD1373  [6]
 LDCM0495  E2913 HEK-293T C43(0.79)  LDD1698  [7]
 LDCM0468  Fragment33 PaTu 8988t C43(0.79)  LDD1347  [6]
 LDCM0427  Fragment51 HEK-293T C43(1.05)  LDD1631  [7]
 LDCM0022  KB02 22RV1 C43(1.49)  LDD2243  [2]
 LDCM0023  KB03 22RV1 C43(2.15)  LDD2660  [2]
 LDCM0024  KB05 OVCAR-3 C43(1.77)  LDD3365  [2]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) SGT family O43765
Small glutamine-rich tetratricopeptide repeat-containing protein beta (SGTB) SGT family Q96EQ0
Ubiquilin-1 (UBQLN1) . Q9UMX0
Ubiquilin-2 (UBQLN2) . Q9UHD9

The Drug(s) Related To This Target

Approved
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Copper . DB09130

References

1 Tranylcypromine specificity for monoamine oxidase is limited by promiscuous protein labelling and lysosomal trapping. RSC Chem Biol. 2020 Aug 12;1(4):209-213. doi: 10.1039/d0cb00048e. eCollection 2020 Oct 1.
Mass spectrometry data entry: PXD018580
2 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
3 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377
4 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
5 Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20.
Mass spectrometry data entry: PXD007570
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402