Details of the Probe

General Information of Probe

Probe ID
LDPC0523
Probe Name
C293
Synonyms
Z3426140063
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 334.4
Lipid-water partition coefficient (xlogp) 2.5
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C20H22N4O
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-1-(1,3,4,5-tetrahydro-[1,4]diazepino[1,2-a]indol-2-yl)propan-1-one
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)N2CCCN3C(=CC4=CC=CC=C43)C2
InChI
InChI=1S/C20H22N4O/c1-2-3-10-20(21-22-20)11-9-19(25)23-12-6-13-24-17(15-23)14-16-7-4-5-8-18(16)24/h1,4-5,7-8,14H,3,6,9-13,15H2
InChIKey
HYFKDPSFOCZWND-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

158 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) LDTP12639 22.32  LDD1963 
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 25.63  LDD1963 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 19.56  LDD1963 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 25.99  LDD1963 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 20.82  LDD1963 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 21.26  LDD1963 
Acid ceramidase (ASAH1) LDTP05905 42.81  LDD1963 
Adenosine 5'-monophosphoramidase HINT3 (HINT3) LDTP12415 17.75  LDD1963 
ADP-dependent glucokinase (ADPGK) LDTP11127 52.71  LDD1963 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 42.22  LDD1963 
All trans-polyprenyl-diphosphate synthase PDSS1 (PDSS1) LDTP07104 17.75  LDD1963 
Alpha-galactosidase A (GLA) LDTP02141 18.90  LDD1963 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 16.00  LDD1963 
Antigen peptide transporter 1 (TAP1) LDTP05408 18.13  LDD1963 
Atlastin-2 (ATL2) LDTP09251 21.11  LDD1963 
Beta-1,3-galactosyltransferase 6 (B3GALT6) LDTP10530 15.89  LDD1963 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 16.00  LDD1963 
Beta-galactosidase (GLB1) LDTP02837 18.77  LDD1963 
Beta-glucuronidase (GUSB) LDTP02260 19.16  LDD1963 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 20.68  LDD1963 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 23.43  LDD1963 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 41.93  LDD1963 
Calcium-independent phospholipase A2-gamma (PNPLA8) LDTP12318 32.00  LDD1963 
Calcyclin-binding protein (CACYBP) LDTP12163 17.15  LDD1963 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 42.81  LDD1963 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 27.47  LDD1963 
Catechol O-methyltransferase (COMT) LDTP03145 36.50  LDD1963 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 78.79  LDD1963 
Cell division cycle protein 23 homolog (CDC23) LDTP13408 27.28  LDD1963 
Ceramide synthase 2 (CERS2) LDTP10329 28.05  LDD1963 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 26.35  LDD1963 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 54.95  LDD1963 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 70.03  LDD1963 
Cytochrome b5 type B (CYB5B) LDTP00697 99.73  LDD1963 
Cytochrome c oxidase assembly factor 7 (COA7) LDTP10137 15.89  LDD1963 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 43.41  LDD1963 
DCN1-like protein 4 (DCUN1D4) LDTP09799 42.22  LDD1963 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 27.86  LDD1963 
Dehydrodolichyl diphosphate synthase complex subunit DHDDS (DHDDS) LDTP08177 27.86  LDD1963 
Dehydrogenase/reductase SDR family member 7 (DHRS7) LDTP13959 15.89  LDD1963 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 31.12  LDD1963 
Delta(24)-sterol reductase (DHCR24) LDTP06375 26.54  LDD1963 
Deoxyhypusine hydroxylase (DOHH) LDTP11225 48.17  LDD1963 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 23.75  LDD1963 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 21.11  LDD1963 
Dihydrofolate reductase (DHFR) LDTP01769 21.86  LDD1963 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 26.72  LDD1963 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 17.15  LDD1963 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 99.73  LDD1963 
E3 ubiquitin-protein ligase listerin (LTN1) LDTP01430 21.11  LDD1963 
E3 ubiquitin-protein ligase RNF14 (RNF14) LDTP13154 34.06  LDD1963 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 31.34  LDD1963 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 36.25  LDD1963 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 18.13  LDD1963 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 24.42  LDD1963 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 22.16  LDD1963 
Epoxide hydrolase 1 (EPHX1) LDTP02175 22.47  LDD1963 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 34.06  LDD1963 
Glutathione hydrolase 7 (GGT7) LDTP13367 20.53  LDD1963 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 33.13  LDD1963 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 28.64  LDD1963 
GTP-binding protein Rheb (RHEB) LDTP06371 18.25  LDD1963 
GTP-binding protein SAR1a (SAR1A) LDTP12470 19.29  LDD1963 
GTP:AMP phosphotransferase AK3, mitochondrial (AK3) LDTP13352 63.12  LDD1963 
Heme A synthase COX15 (COX15) LDTP07931 19.56  LDD1963 
Heme oxygenase 1 (HMOX1) LDTP02359 90.51  LDD1963 
Heme oxygenase 2 (HMOX2) LDTP03540 55.72  LDD1963 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 35.02  LDD1963 
Hexokinase-2 (HK2) LDTP04531 18.77  LDD1963 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 20.53  LDD1963 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 64.00  LDD1963 
Ketosamine-3-kinase (FN3KRP) LDTP16025 16.68  LDD1963 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 20.39  LDD1963 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 19.70  LDD1963 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 22.47  LDD1963 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 71.51  LDD1963 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 17.63  LDD1963 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 37.27  LDD1963 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 19.97  LDD1963 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 24.25  LDD1963 
Lysosomal acid phosphatase (ACP2) LDTP02539 19.03  LDD1963 
Lysosomal protective protein (CTSA) LDTP02505 36.76  LDD1963 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 35.51  LDD1963 
Maleylacetoacetate isomerase (GSTZ1) LDTP00844 21.71  LDD1963 
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCAT) LDTP08512 16.11  LDD1963 
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) LDTP10930 21.86  LDD1963 
Metalloendopeptidase OMA1, mitochondrial (OMA1) LDTP10249 19.70  LDD1963 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 32.67  LDD1963 
Minor histocompatibility antigen H13 (HM13) LDTP09396 30.06  LDD1963 
Mitochondrial ribonuclease P catalytic subunit (PRORP) LDTP00536 17.27  LDD1963 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 19.56  LDD1963 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 23.43  LDD1963 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 18.51  LDD1963 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 20.53  LDD1963 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 18.90  LDD1963 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 27.86  LDD1963 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 19.03  LDD1963 
NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) LDTP01219 18.64  LDD1963 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 20.11  LDD1963 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 37.01  LDD1963 
NADH-cytochrome b5 reductase 3 (CYB5R3) LDTP01770 22.16  LDD1963 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 23.10  LDD1963 
NADPH--cytochrome P450 reductase (POR) LDTP02848 24.59  LDD1963 
Obg-like ATPase 1 (OLA1) LDTP12610 18.77  LDD1963 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 60.55  LDD1963 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 18.51  LDD1963 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 18.00  LDD1963 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 25.99  LDD1963 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 46.85  LDD1963 
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) LDTP01562 19.56  LDD1963 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 18.90  LDD1963 
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3) LDTP09155 33.36  LDD1963 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 27.28  LDD1963 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 20.97  LDD1963 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 27.47  LDD1963 
Presequence protease, mitochondrial (PITRM1) LDTP07003 21.71  LDD1963 
Probable ATP-dependent RNA helicase DDX28 (DDX28) LDTP12633 26.17  LDD1963 
Probable methyltransferase TARBP1 (TARBP1) LDTP05850 16.45  LDD1963 
Prostaglandin reductase 3 (PTGR3) LDTP15422 16.68  LDD1963 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 18.77  LDD1963 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 22.47  LDD1963 
Protein disulfide-isomerase (P4HB) LDTP02188 18.25  LDD1963 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 22.01  LDD1963 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 66.26  LDD1963 
Protein kinase C delta type (PRKCD) LDTP05461 20.82  LDD1963 
Protein O-mannosyl-transferase TMTC3 (TMTC3) LDTP07868 17.88  LDD1963 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 79.89  LDD1963 
Pseudouridylate synthase RPUSD2 (RPUSD2) LDTP15370 17.63  LDD1963 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 16.34  LDD1963 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 20.97  LDD1963 
Ras-related protein Rab-10 (RAB10) LDTP04895 18.25  LDD1963 
Ras-related protein Rab-11B (RAB11B) LDTP06501 28.64  LDD1963 
Ras-related protein Rab-24 (RAB24) LDTP10020 21.26  LDD1963 
Ras-related protein Rap-2b (RAP2B) LDTP04911 22.47  LDD1963 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 23.26  LDD1963 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 38.59  LDD1963 
Retinol dehydrogenase 13 (RDH13) LDTP09061 26.54  LDD1963 
Retinol dehydrogenase 14 (RDH14) LDTP12180 16.34  LDD1963 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 21.41  LDD1963 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 26.72  LDD1963 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 17.51  LDD1963 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 38.05  LDD1963 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 24.25  LDD1963 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 21.71  LDD1963 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 25.11  LDD1963 
Squalene monooxygenase (SQLE) LDTP06142 23.26  LDD1963 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 17.27  LDD1963 
Threonine--tRNA ligase, mitochondrial (TARS2) LDTP11319 18.13  LDD1963 
TLC domain-containing protein 1 (TLCD1) LDTP10182 20.39  LDD1963 
Torsin-1B (TOR1B) LDTP00400 17.75  LDD1963 
Trimethyllysine dioxygenase, mitochondrial (TMLHE) LDTP12679 17.51  LDD1963 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 19.29  LDD1963 
tRNA (guanine-N(7)-)-methyltransferase (METTL1) LDTP13140 20.25  LDD1963 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 35.75  LDD1963 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 21.56  LDD1963 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 17.75  LDD1963 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 30.06  LDD1963 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 21.41  LDD1963 
------------------------------------------------------------------------------------
⏷ Show the Full List of 158 Enzyme
117 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 45.89  LDD1963 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 20.53  LDD1963 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 24.76  LDD1963 
ADP/ATP translocase 2 (SLC25A5) LDTP02087 15.89  LDD1963 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 27.28  LDD1963 
Amyloid-beta precursor protein (APP) LDTP02071 29.24  LDD1963 
Annexin A1 (ANXA1) LDTP02010 16.34  LDD1963 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 51.98  LDD1963 
ATP synthase subunit a (MT-ATP6) LDTP01804 66.72  LDD1963 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 17.27  LDD1963 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 37.53  LDD1963 
Autophagy-related protein 16-1 (ATG16L1) LDTP07304 40.79  LDD1963 
BOS complex subunit NCLN (NCLN) LDTP10036 19.29  LDD1963 
BRI3-binding protein (BRI3BP) LDTP15648 73.52  LDD1963 
Calcium uptake protein 2, mitochondrial (MICU2) LDTP08673 17.03  LDD1963 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 26.72  LDD1963 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 23.92  LDD1963 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 70.03  LDD1963 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 22.94  LDD1963 
Derlin-1 (DERL1) LDTP11245 29.04  LDD1963 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) LDTP02058 21.26  LDD1963 
Equilibrative nucleoside transporter 1 (SLC29A1) LDTP10985 18.00  LDD1963 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 54.95  LDD1963 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 20.68  LDD1963 
Essential MCU regulator, mitochondrial (SMDT1) LDTP11927 94.35  LDD1963 
Exportin-4 (XPO4) LDTP11607 19.70  LDD1963 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 17.27  LDD1963 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 16.80  LDD1963 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 25.63  LDD1963 
HIG1 domain family member 2A, mitochondrial (HIGD2A) LDTP15898 16.11  LDD1963 
Importin-7 (IPO7) LDTP01574 20.82  LDD1963 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 17.51  LDD1963 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 30.70  LDD1963 
Lysosome membrane protein 2 (SCARB2) LDTP06034 19.84  LDD1963 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 20.25  LDD1963 
Major facilitator superfamily domain-containing protein 10 (MFSD10) LDTP06198 20.39  LDD1963 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 24.42  LDD1963 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 34.30  LDD1963 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 18.64  LDD1963 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 31.34  LDD1963 
Metal transporter CNNM3 (CNNM3) LDTP09144 21.56  LDD1963 
Metaxin-1 (MTX1) LDTP05900 34.78  LDD1963 
MICOS complex subunit MIC26 (APOO) LDTP11250 46.85  LDD1963 
MICOS complex subunit MIC60 (IMMT) LDTP06660 16.91  LDD1963 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 18.38  LDD1963 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 27.86  LDD1963 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 26.17  LDD1963 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 41.64  LDD1963 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 51.98  LDD1963 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 39.12  LDD1963 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 91.77  LDD1963 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 81.01  LDD1963 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 39.95  LDD1963 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 42.52  LDD1963 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 41.64  LDD1963 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 37.27  LDD1963 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 41.64  LDD1963 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 20.39  LDD1963 
Mpv17-like protein 2 (MPV17L2) LDTP14952 23.75  LDD1963 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 20.39  LDD1963 
Nucleoporin NDC1 (NDC1) LDTP11213 20.97  LDD1963 
Nucleoporin Nup37 (NUP37) LDTP09203 17.63  LDD1963 
Osteopetrosis-associated transmembrane protein 1 (OSTM1) LDTP08327 37.01  LDD1963 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 25.63  LDD1963 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 21.26  LDD1963 
Peroxisomal membrane protein 11A (PEX11A) LDTP01160 17.51  LDD1963 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 17.88  LDD1963 
PRA1 family protein 2 (PRAF2) LDTP01060 24.08  LDD1963 
Prosaposin (PSAP) LDTP02215 20.11  LDD1963 
Protein FAM8A1 (FAM8A1) LDTP16190 22.16  LDD1963 
Protein GPR107 (GPR107) LDTP07236 34.06  LDD1963 
Protein RER1 (RER1) LDTP00590 16.00  LDD1963 
Protein tweety homolog 3 (TTYH3) LDTP11615 52.71  LDD1963 
Protein wntless homolog (WLS) LDTP07156 40.79  LDD1963 
Proton-coupled amino acid transporter 1 (SLC36A1) LDTP08016 17.88  LDD1963 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 34.54  LDD1963 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 30.48  LDD1963 
Reticulon-1 (RTN1) LDTP06633 20.97  LDD1963 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 21.71  LDD1963 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 37.53  LDD1963 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 27.86  LDD1963 
Signal recognition particle subunit SRP68 (SRP68) LDTP13262 36.00  LDD1963 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 69.55  LDD1963 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 56.10  LDD1963 
Sorting nexin-27 (SNX27) LDTP10533 17.03  LDD1963 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 56.10  LDD1963 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 31.78  LDD1963 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 23.26  LDD1963 
Stomatin (STOM) LDTP03380 24.25  LDD1963 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 66.26  LDD1963 
Syntaxin-3 (STX3) LDTP05811 16.56  LDD1963 
Syntaxin-5 (STX5) LDTP05780 17.88  LDD1963 
Syntaxin-6 (STX6) LDTP00857 32.67  LDD1963 
Syntenin-1 (SDCBP) LDTP00310 23.92  LDD1963 
Target of Myb1 membrane trafficking protein (TOM1) LDTP01051 19.97  LDD1963 
Tetraspanin-10 (TSPAN10) LDTP15967 16.11  LDD1963 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 29.65  LDD1963 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 99.73  LDD1963 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 25.11  LDD1963 
Transmembrane protein 126A (TMEM126A) LDTP15948 41.07  LDD1963 
Transmembrane protein 160 (TMEM160) LDTP20002 83.87  LDD1963 
Transmembrane protein 199 (TMEM199) LDTP08881 22.01  LDD1963 
Transmembrane protein 205 (TMEM205) LDTP07667 16.34  LDD1963 
Transmembrane protein 214 (TMEM214) LDTP07477 17.39  LDD1963 
Transmembrane protein 230 (TMEM230) LDTP10065 26.54  LDD1963 
Transmembrane protein 245 (TMEM245) LDTP15979 24.76  LDD1963 
Transmembrane protein 33 (TMEM33) LDTP04787 18.64  LDD1963 
Transmembrane protein 59 (TMEM59) LDTP11406 16.91  LDD1963 
Transmembrane protein 87A (TMEM87A) LDTP15481 39.67  LDD1963 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 22.16  LDD1963 
Vacuole membrane protein 1 (VMP1) LDTP10343 37.53  LDD1963 
Vezatin (VEZT) LDTP12191 21.26  LDD1963 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 36.50  LDD1963 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 49.18  LDD1963 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 32.00  LDD1963 
Volume-regulated anion channel subunit LRRC8C (LRRC8C) LDTP09459 16.22  LDD1963 
Wolframin (WFS1) LDTP01380 17.75  LDD1963 
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⏷ Show the Full List of 117 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 16.91  LDD1963 
Peregrin (BRPF1) LDTP04683 18.64  LDD1963 
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1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Leukocyte surface antigen CD47 (CD47) LDTP05572 24.42  LDD1963 
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119 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 17.27  LDD1963 
AP-3 complex subunit mu-1 (AP3M1) LDTP13908 21.71  LDD1963 
Apolipoprotein L2 (APOL2) LDTP11076 85.04  LDD1963 
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP3) LDTP10656 24.93  LDD1963 
Armadillo-like helical domain-containing protein 3 (ARMH3) LDTP15002 41.36  LDD1963 
ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) LDTP14716 18.00  LDD1963 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 18.77  LDD1963 
BET1 homolog (BET1) LDTP00555 17.51  LDD1963 
Calmodulin-3 (CALM3) LDTP02443 38.59  LDD1963 
Calumenin (CALU) LDTP00887 17.03  LDD1963 
Capping protein-inhibiting regulator of actin dynamics (CRACD) LDTP07839 49.87  LDD1963 
CCR4-NOT transcription complex subunit 9 (CNOT9) LDTP09813 19.70  LDD1963 
Centrin-2 (CETN2) LDTP03926 57.68  LDD1963 
Clustered mitochondria protein homolog (CLUH) LDTP14486 19.03  LDD1963 
Coatomer subunit epsilon (COPE) LDTP00376 23.75  LDD1963 
Cold-inducible RNA-binding protein (CIRBP) LDTP06022 18.51  LDD1963 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 30.70  LDD1963 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 88.03  LDD1963 
Cytochrome c oxidase assembly protein COX11, mitochondrial (COX11) LDTP14277 15.89  LDD1963 
Cytochrome c oxidase assembly protein COX14 (COX14) LDTP15741 24.25  LDD1963 
Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2) LDTP05855 15.89  LDD1963 
DDRGK domain-containing protein 1 (DDRGK1) LDTP10403 17.03  LDD1963 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 18.25  LDD1963 
Dynactin subunit 4 (DCTN4) LDTP13402 16.56  LDD1963 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 28.25  LDD1963 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 17.75  LDD1963 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 20.11  LDD1963 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 53.82  LDD1963 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 26.72  LDD1963 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 22.78  LDD1963 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 32.22  LDD1963 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 22.01  LDD1963 
Ganglioside GM2 activator (GM2A) LDTP02927 25.11  LDD1963 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 34.30  LDD1963 
HAUS augmin-like complex subunit 1 (HAUS1) LDTP10184 20.53  LDD1963 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 21.11  LDD1963 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 17.03  LDD1963 
HEAT repeat-containing protein 3 (HEATR3) LDTP15253 16.00  LDD1963 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 16.91  LDD1963 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 17.39  LDD1963 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 17.39  LDD1963 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 15.89  LDD1963 
Immediate early response 3-interacting protein 1 (IER3IP1) LDTP14164 17.75  LDD1963 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 26.72  LDD1963 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 45.57  LDD1963 
KH domain-containing RNA-binding protein QKI (QKI) LDTP10700 17.75  LDD1963 
KH domain-containing, RNA-binding, signal transduction-associated protein 3 (KHDRBS3) LDTP01246 17.15  LDD1963 
Kinetochore-associated protein 1 (KNTC1) LDTP04382 25.63  LDD1963 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 20.53  LDD1963 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 17.03  LDD1963 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 38.05  LDD1963 
Lipase maturation factor 2 (LMF2) LDTP15887 29.04  LDD1963 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 35.26  LDD1963 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 20.53  LDD1963 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 30.06  LDD1963 
Microtubule nucleation factor SSNA1 (SSNA1) LDTP00871 34.06  LDD1963 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 17.15  LDD1963 
Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A) LDTP00913 20.11  LDD1963 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 20.97  LDD1963 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 97.68  LDD1963 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 94.35  LDD1963 
Mitochondrial import receptor subunit TOM6 homolog (TOMM6) LDTP10113 60.13  LDD1963 
Nicastrin (NCSTN) LDTP09787 17.15  LDD1963 
Nucleobindin-1 (NUCB1) LDTP05375 19.43  LDD1963 
Nucleobindin-2 (NUCB2) LDTP05160 55.33  LDD1963 
Nurim (NRM) LDTP08606 22.01  LDD1963 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 25.46  LDD1963 
Optic atrophy 3 protein (OPA3) LDTP16006 25.28  LDD1963 
Oxysterol-binding protein-related protein 9 (OSBPL9) LDTP10825 20.82  LDD1963 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 99.73  LDD1963 
Polyadenylate-binding protein-interacting protein 2 (PAIP2) LDTP11044 26.54  LDD1963 
Programmed cell death protein 5 (PDCD5) LDTP00417 24.42  LDD1963 
Protein CEBPZOS (CEBPZOS) LDTP18883 60.13  LDD1963 
Protein CutA (CUTA) LDTP01075 25.46  LDD1963 
Protein FAM114A2 (FAM114A2) LDTP16080 35.26  LDD1963 
Protein FAM162A (FAM162A) LDTP10056 37.53  LDD1963 
Protein FAM177A1 (FAM177A1) LDTP15398 27.67  LDD1963 
Protein FAM3C (FAM3C) LDTP09773 22.63  LDD1963 
Protein Hikeshi (HIKESHI) LDTP06892 56.10  LDD1963 
Protein jagunal homolog 1 (JAGN1) LDTP08904 22.63  LDD1963 
Protein LYRIC (MTDH) LDTP08224 27.47  LDD1963 
Protein PBDC1 (PBDC1) LDTP19924 16.34  LDD1963 
Protein SET (SET) LDTP05277 16.56  LDD1963 
Protein unc-119 homolog B (UNC119B) LDTP00105 40.22  LDD1963 
Protein VAC14 homolog (VAC14) LDTP05586 25.63  LDD1963 
Protein YIF1A (YIF1A) LDTP01494 30.91  LDD1963 
Ran guanine nucleotide release factor (RANGRF) LDTP12287 39.67  LDD1963 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 28.64  LDD1963 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 30.70  LDD1963 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 17.63  LDD1963 
Reticulocalbin-2 (RCN2) LDTP06097 25.46  LDD1963 
Reticulon-3 (RTN3) LDTP01522 58.49  LDD1963 
Reticulon-4 (RTN4) LDTP12412 39.95  LDD1963 
RNA-binding protein FUS (FUS) LDTP03775 19.03  LDD1963 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 21.41  LDD1963 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 20.11  LDD1963 
Small integral membrane protein 12 (SMIM12) LDTP19859 33.59  LDD1963 
Small ribosomal subunit protein uS14m (MRPS14) LDTP01050 47.50  LDD1963 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 16.45  LDD1963 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 19.43  LDD1963 
Synaptic vesicle glycoprotein 2A (SV2A) LDTP07934 16.56  LDD1963 
Synaptogyrin-2 (SYNGR2) LDTP00859 36.25  LDD1963 
Syntaxin-18 (STX18) LDTP13086 49.18  LDD1963 
T-complex protein 1 subunit eta (CCT7) LDTP10990 19.97  LDD1963 
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) LDTP14263 24.76  LDD1963 
Testis-expressed protein 264 (TEX264) LDTP14259 79.34  LDD1963 
Tetraspanin-6 (TSPAN6) LDTP14458 99.73  LDD1963 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 20.39  LDD1963 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 58.08  LDD1963 
TraB domain-containing protein (TRABD) LDTP19963 36.50  LDD1963 
Transducin beta-like protein 2 (TBL2) LDTP16285 22.32  LDD1963 
Translation initiation factor eIF2B subunit gamma (EIF2B3) LDTP12476 17.03  LDD1963 
Translocon-associated protein subunit delta (SSR4) LDTP04425 17.63  LDD1963 
Transmembrane protein 209 (TMEM209) LDTP18272 18.25  LDD1963 
U6 snRNA-associated Sm-like protein LSm3 (LSM3) LDTP04979 19.84  LDD1963 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 33.13  LDD1963 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 22.16  LDD1963 
Vimentin (VIM) LDTP02297 17.03  LDD1963 
Zinc finger CCHC domain-containing protein 3 (ZCCHC3) LDTP12623 22.63  LDD1963 
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⏷ Show the Full List of 119 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1963 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587