Details of the Target

General Information of Target

Target ID	LDTP16032
Target Name	Retinoid-inducible serine carboxypeptidase (SCPEP1)
Gene Name	SCPEP1
Gene ID	59342
Synonyms	RISC; SCP1; Retinoid-inducible serine carboxypeptidase; EC 3.4.16.-; Serine carboxypeptidase 1
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MGRPAGLFPPLCPFLGFRPEACWERHMQIERAPSVPPFLRWAGYRPGPVRRRGKVELIKF VRVQWRRPQVEWRRRRWGPGPGASMAGSEELGLREDTLRVLAAFLRRGEAAGSPVPTPPR SPAQEEPTDFLSRLRRCLPCSLGRGAAPSESPRPCSLPIRPCYGLEPGPATPDFYALVAQ RLEQLVQEQLKSPPSPELQGPPSTEKEAILRRLVALLEEEAEVINQKLASDPALRSKLVR LSSDSFARLVELFCSRDDSSRPSRACPGPPPPSPEPLARLALAMELSRRVAGLGGTLAGL SVEHVHSFTPWIQAHGGWEGILAVSPVDLNLPLD
Target Bioclass	Enzyme
Family	Peptidase S10 family
Subcellular location	Secreted
Function	May be involved in vascular wall and kidney homeostasis.
Uniprot ID	Q9HB40
Ensemble ID	ENST00000262288.8
HGNC ID	HGNC:29507
ChEMBL ID	CHEMBL2189131

Target Site Mutations in Different Cell Lines

Cell line	Mutation details	Probe for labeling this protein in this cell
CHL1	SNV: p.A249P	.
MCC13	SNV: p.G177C	.
MOLT4	SNV: p.L94I	IA-alkyne Probe Info
NCIH1155	SNV: p.V349I	.
SNU449	SNV: p.Y57H	.

Probe(s) Labeling This Target

ABPP Probe

Click To Hide/Show 18 Probe Related to This Target

Probe name	Binding Site(Ratio)	Interaction ID	Ref
m-APA Probe Info	15.00	LDD0402	[2]
Alkylaryl probe 1 Probe Info	5.00	LDD0385	[3]
C-Sul Probe Info	5.92	LDD0066	[4]
TH211 Probe Info	Y270(11.24)	LDD0257	[5]
P11 Probe Info	17.93	LDD0201	[6]
Alkylaryl probe 2 Probe Info	3.00	LDD0390	[3]
BTD Probe Info	C152(1.36)	LDD2099	[7]
FBPP2 Probe Info	5.29	LDD0054	[8]
AHL-Pu-1 Probe Info	C152(3.98)	LDD0170	[9]
EA-probe Probe Info	N.A.	LDD0440	[10]
DBIA Probe Info	C295(4.19); C62(4.19)	LDD0812	[11]
IA-alkyne Probe Info	N.A.	LDD0036	[12]
Lodoacetamide azide Probe Info	N.A.	LDD0037	[12]
IPM Probe Info	N.A.	LDD0005	[13]
NHS Probe Info	N.A.	LDD0010	[13]
TFBX Probe Info	N.A.	LDD0148	[14]
Phosphinate-6 Probe Info	N.A.	LDD0018	[15]
AOyne Probe Info	15.00	LDD0443	[16]

PAL-AfBPP Probe

Click To Hide/Show 191 Probe Related to This Target

Probe name	Binding Site(Ratio)	Interaction ID	Ref
C001 Probe Info	10.78	LDD1711	[17]
C004 Probe Info	14.83	LDD1714	[17]
C007 Probe Info	6.73	LDD1716	[17]
C008 Probe Info	5.35	LDD1717	[17]
C010 Probe Info	6.59	LDD1719	[17]
C011 Probe Info	8.22	LDD1720	[17]
C015 Probe Info	5.46	LDD1724	[17]
C018 Probe Info	10.85	LDD1726	[17]
C022 Probe Info	25.99	LDD1728	[17]
C026 Probe Info	10.41	LDD1732	[17]
C036 Probe Info	8.11	LDD1736	[17]
C039 Probe Info	11.79	LDD1739	[17]
C040 Probe Info	8.69	LDD1740	[17]
C041 Probe Info	29.86	LDD1741	[17]
C042 Probe Info	4.92	LDD1742	[17]
C044 Probe Info	5.58	LDD1743	[17]
C045 Probe Info	15.56	LDD1744	[17]
C049 Probe Info	5.21	LDD1747	[17]
C053 Probe Info	7.52	LDD1751	[17]
C060 Probe Info	6.19	LDD1757	[17]
C063 Probe Info	30.70	LDD1760	[17]
C064 Probe Info	6.63	LDD1761	[17]
C070 Probe Info	24.59	LDD1766	[17]
C071 Probe Info	9.32	LDD1767	[17]
C072 Probe Info	11.00	LDD1768	[17]
C073 Probe Info	9.92	LDD1769	[17]
C078 Probe Info	5.06	LDD1771	[17]
C079 Probe Info	5.70	LDD1772	[17]
C082 Probe Info	16.56	LDD1774	[17]
C085 Probe Info	17.88	LDD1777	[17]
C087 Probe Info	53.82	LDD1779	[17]
C089 Probe Info	9.71	LDD1781	[17]
C091 Probe Info	17.15	LDD1782	[17]
C106 Probe Info	51.98	LDD1793	[17]
C107 Probe Info	9.85	LDD1794	[17]
C108 Probe Info	34.06	LDD1795	[17]
C112 Probe Info	30.70	LDD1799	[17]
C115 Probe Info	14.62	LDD1802	[17]
C117 Probe Info	19.29	LDD1804	[17]
C130 Probe Info	19.70	LDD1812	[17]
C134 Probe Info	21.86	LDD1816	[17]
C135 Probe Info	10.41	LDD1817	[17]
C139 Probe Info	21.56	LDD1821	[17]
C140 Probe Info	19.16	LDD1822	[17]
C141 Probe Info	16.91	LDD1823	[17]
C142 Probe Info	4.99	LDD1824	[17]
C143 Probe Info	18.77	LDD1825	[17]
C145 Probe Info	16.91	LDD1827	[17]
C147 Probe Info	12.91	LDD1829	[17]
C149 Probe Info	13.18	LDD1830	[17]
C153 Probe Info	33.59	LDD1834	[17]
C159 Probe Info	24.08	LDD1839	[17]
C160 Probe Info	19.43	LDD1840	[17]
C161 Probe Info	27.86	LDD1841	[17]
C163 Probe Info	9.06	LDD1843	[17]
C164 Probe Info	11.16	LDD1844	[17]
C165 Probe Info	24.59	LDD1845	[17]
C170 Probe Info	48.84	LDD1850	[17]
C171 Probe Info	16.34	LDD1851	[17]
C177 Probe Info	18.77	LDD1856	[17]
C178 Probe Info	71.51	LDD1857	[17]
C182 Probe Info	6.32	LDD1860	[17]
C183 Probe Info	12.04	LDD1861	[17]
C184 Probe Info	8.82	LDD1862	[17]
C186 Probe Info	26.72	LDD1864	[17]
C187 Probe Info	38.32	LDD1865	[17]
C193 Probe Info	7.52	LDD1869	[17]
C194 Probe Info	16.80	LDD1870	[17]
C195 Probe Info	7.06	LDD1871	[17]
C197 Probe Info	18.90	LDD1873	[17]
C198 Probe Info	17.75	LDD1874	[17]
C201 Probe Info	55.72	LDD1877	[17]
C205 Probe Info	11.24	LDD1880	[17]
C206 Probe Info	52.71	LDD1881	[17]
C208 Probe Info	30.70	LDD1883	[17]
C211 Probe Info	38.05	LDD1885	[17]
C212 Probe Info	6.23	LDD1886	[17]
C213 Probe Info	53.45	LDD1887	[17]
C218 Probe Info	12.30	LDD1892	[17]
C219 Probe Info	9.85	LDD1893	[17]
C220 Probe Info	45.25	LDD1894	[17]
C221 Probe Info	14.32	LDD1895	[17]
C223 Probe Info	22.01	LDD1897	[17]
C225 Probe Info	14.83	LDD1898	[17]
C226 Probe Info	16.80	LDD1899	[17]
C228 Probe Info	32.90	LDD1901	[17]
C229 Probe Info	14.42	LDD1902	[17]
C231 Probe Info	13.27	LDD1904	[17]
C232 Probe Info	74.03	LDD1905	[17]
C233 Probe Info	29.65	LDD1906	[17]
C237 Probe Info	18.64	LDD1910	[17]
C239 Probe Info	8.69	LDD1912	[17]
C240 Probe Info	8.34	LDD1913	[17]
C243 Probe Info	16.22	LDD1916	[17]
C246 Probe Info	12.91	LDD1919	[17]
C249 Probe Info	42.52	LDD1922	[17]
C255 Probe Info	5.31	LDD1928	[17]
C258 Probe Info	5.17	LDD1931	[17]
C264 Probe Info	37.27	LDD1935	[17]
C265 Probe Info	28.64	LDD1936	[17]
C270 Probe Info	15.45	LDD1940	[17]
C273 Probe Info	5.31	LDD1943	[17]
C277 Probe Info	13.36	LDD1947	[17]
C280 Probe Info	32.90	LDD1950	[17]
C281 Probe Info	7.94	LDD1951	[17]
C282 Probe Info	19.70	LDD1952	[17]
C284 Probe Info	43.41	LDD1954	[17]
C286 Probe Info	13.45	LDD1956	[17]
C287 Probe Info	14.03	LDD1957	[17]
C288 Probe Info	11.39	LDD1958	[17]
C290 Probe Info	7.01	LDD1960	[17]
C293 Probe Info	38.59	LDD1963	[17]
C296 Probe Info	26.17	LDD1966	[17]
C299 Probe Info	7.16	LDD1968	[17]
C302 Probe Info	24.08	LDD1971	[17]
C303 Probe Info	11.08	LDD1972	[17]
C305 Probe Info	24.42	LDD1974	[17]
C307 Probe Info	7.84	LDD1975	[17]
C310 Probe Info	16.22	LDD1977	[17]
C314 Probe Info	45.57	LDD1981	[17]
C326 Probe Info	25.99	LDD1990	[17]
C328 Probe Info	5.94	LDD1992	[17]
C329 Probe Info	7.26	LDD1993	[17]
C334 Probe Info	8.51	LDD1997	[17]
C336 Probe Info	7.89	LDD1999	[17]
C339 Probe Info	6.06	LDD2002	[17]
C340 Probe Info	12.82	LDD2003	[17]
C342 Probe Info	5.03	LDD2004	[17]
C343 Probe Info	23.75	LDD2005	[17]
C346 Probe Info	25.11	LDD2007	[17]
C348 Probe Info	16.56	LDD2009	[17]
C349 Probe Info	27.67	LDD2010	[17]
C350 Probe Info	42.81	LDD2011	[17]
C353 Probe Info	7.46	LDD2014	[17]
C354 Probe Info	18.25	LDD2015	[17]
C355 Probe Info	99.73	LDD2016	[17]
C356 Probe Info	29.04	LDD2017	[17]
C357 Probe Info	14.83	LDD2018	[17]
C359 Probe Info	8.06	LDD2020	[17]
C360 Probe Info	9.45	LDD2021	[17]
C361 Probe Info	17.88	LDD2022	[17]
C362 Probe Info	45.57	LDD2023	[17]
C363 Probe Info	37.79	LDD2024	[17]
C364 Probe Info	39.40	LDD2025	[17]
C367 Probe Info	5.10	LDD2028	[17]
C369 Probe Info	4.99	LDD2030	[17]
C373 Probe Info	5.35	LDD2033	[17]
C376 Probe Info	19.03	LDD2036	[17]
C378 Probe Info	8.40	LDD2037	[17]
C380 Probe Info	10.48	LDD2039	[17]
C382 Probe Info	13.83	LDD2041	[17]
C383 Probe Info	34.54	LDD2042	[17]
C385 Probe Info	7.78	LDD2044	[17]
C386 Probe Info	16.34	LDD2045	[17]
C387 Probe Info	9.58	LDD2046	[17]
C390 Probe Info	93.70	LDD2049	[17]
C393 Probe Info	8.28	LDD2052	[17]
C396 Probe Info	6.54	LDD2055	[17]
C399 Probe Info	15.03	LDD2058	[17]
C403 Probe Info	17.63	LDD2061	[17]
C405 Probe Info	8.88	LDD2063	[17]
C407 Probe Info	12.82	LDD2064	[17]
C408 Probe Info	6.92	LDD2065	[17]
C409 Probe Info	5.58	LDD2066	[17]
C413 Probe Info	26.17	LDD2069	[17]
C414 Probe Info	5.98	LDD2070	[17]
C419 Probe Info	26.72	LDD2074	[17]
C420 Probe Info	59.71	LDD2075	[17]
C425 Probe Info	20.39	LDD2080	[17]
C428 Probe Info	6.68	LDD2083	[17]
C429 Probe Info	74.54	LDD2084	[17]
C431 Probe Info	99.73	LDD2086	[17]
C433 Probe Info	15.78	LDD2088	[17]
FFF probe11 Probe Info	20.00	LDD0471	[18]
FFF probe12 Probe Info	20.00	LDD0473	[18]
FFF probe13 Probe Info	20.00	LDD0475	[18]
FFF probe14 Probe Info	20.00	LDD0477	[18]
FFF probe15 Probe Info	20.00	LDD0478	[18]
FFF probe2 Probe Info	19.28	LDD0463	[18]
FFF probe3 Probe Info	20.00	LDD0464	[18]
FFF probe4 Probe Info	20.00	LDD0466	[18]
FFF probe6 Probe Info	11.17	LDD0467	[18]
FFF probe7 Probe Info	20.00	LDD0483	[18]
FFF probe9 Probe Info	20.00	LDD0470	[18]
JN0003 Probe Info	20.00	LDD0469	[18]
Kambe_31 Probe Info	6.01	LDD0128	[19]
BD-F Probe Info	N263(0.00); T264(0.00); M258(0.00); I260(0.00)	LDD0024	[20]
LD-F Probe Info	A256(0.00); T264(0.00); E261(0.00); M258(0.00)	LDD0015	[20]
TM-F Probe Info	A256(0.00); I259(0.00); M258(0.00)	LDD0020	[20]
DA-2 Probe Info	N.A.	LDD0072	[21]
OEA-DA Probe Info	20.00	LDD0046	[22]

Competitor(s) Related to This Target

Competitor ID	Name	Cell line	Binding Site(Ratio)	Interaction ID	Ref
LDCM0524	2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide	MDA-MB-231	C152(1.04)	LDD2117	[7]
LDCM0025	4SU-RNA	DM93	C152(3.98)	LDD0170	[9]
LDCM0026	4SU-RNA+native RNA	DM93	C152(3.50)	LDD0171	[9]
LDCM0214	AC1	HEK-293T	C295(4.19); C62(4.19)	LDD0812	[11]
LDCM0215	AC10	HEK-293T	C297(0.92); C295(0.75); C62(0.75)	LDD0813	[11]
LDCM0216	AC100	HEK-293T	C295(0.53); C62(0.53)	LDD0814	[11]
LDCM0217	AC101	HEK-293T	C295(0.54); C62(0.54)	LDD0815	[11]
LDCM0218	AC102	HEK-293T	C295(0.71); C62(0.71)	LDD0816	[11]
LDCM0219	AC103	HEK-293T	C295(0.68); C62(0.68)	LDD0817	[11]
LDCM0220	AC104	HEK-293T	C295(0.83); C62(0.83)	LDD0818	[11]
LDCM0221	AC105	HEK-293T	C295(0.87); C62(0.87)	LDD0819	[11]
LDCM0222	AC106	HEK-293T	C295(1.15); C62(1.15)	LDD0820	[11]
LDCM0223	AC107	HEK-293T	C295(1.01); C62(1.01)	LDD0821	[11]
LDCM0224	AC108	HEK-293T	C295(0.78); C62(0.78)	LDD0822	[11]
LDCM0225	AC109	HEK-293T	C295(0.62); C62(0.62)	LDD0823	[11]
LDCM0226	AC11	HEK-293T	C297(0.85); C295(1.24); C62(1.24)	LDD0824	[11]
LDCM0227	AC110	HEK-293T	C295(0.55); C62(0.55)	LDD0825	[11]
LDCM0228	AC111	HEK-293T	C295(0.64); C62(0.64)	LDD0826	[11]
LDCM0229	AC112	HEK-293T	C295(0.58); C62(0.58)	LDD0827	[11]
LDCM0230	AC113	HEK-293T	C295(1.35); C62(1.35)	LDD0828	[11]
LDCM0231	AC114	HEK-293T	C295(0.88); C62(0.88)	LDD0829	[11]
LDCM0232	AC115	HEK-293T	C295(1.63); C62(1.63)	LDD0830	[11]
LDCM0233	AC116	HEK-293T	C295(1.69); C62(1.69)	LDD0831	[11]
LDCM0234	AC117	HEK-293T	C295(0.97); C62(0.97)	LDD0832	[11]
LDCM0235	AC118	HEK-293T	C295(0.76); C62(0.76)	LDD0833	[11]
LDCM0236	AC119	HEK-293T	C295(1.06); C62(1.06)	LDD0834	[11]
LDCM0237	AC12	HEK-293T	C297(1.20); C295(0.98); C62(0.98)	LDD0835	[11]
LDCM0238	AC120	HEK-293T	C295(1.11); C62(1.11)	LDD0836	[11]
LDCM0239	AC121	HEK-293T	C295(1.34); C62(1.34)	LDD0837	[11]
LDCM0240	AC122	HEK-293T	C295(1.15); C62(1.15)	LDD0838	[11]
LDCM0241	AC123	HEK-293T	C295(1.41); C62(1.41)	LDD0839	[11]
LDCM0242	AC124	HEK-293T	C295(0.99); C62(0.99)	LDD0840	[11]
LDCM0243	AC125	HEK-293T	C295(1.90); C62(1.90)	LDD0841	[11]
LDCM0244	AC126	HEK-293T	C295(1.04); C62(1.04)	LDD0842	[11]
LDCM0245	AC127	HEK-293T	C295(0.95); C62(0.95)	LDD0843	[11]
LDCM0246	AC128	HEK-293T	C295(1.01); C62(1.01)	LDD0844	[11]
LDCM0247	AC129	HEK-293T	C295(0.71); C62(0.71)	LDD0845	[11]
LDCM0249	AC130	HEK-293T	C295(0.74); C62(0.74)	LDD0847	[11]
LDCM0250	AC131	HEK-293T	C295(0.82); C62(0.82)	LDD0848	[11]
LDCM0251	AC132	HEK-293T	C295(0.74); C62(0.74)	LDD0849	[11]
LDCM0252	AC133	HEK-293T	C295(0.75); C62(0.75)	LDD0850	[11]
LDCM0253	AC134	HEK-293T	C295(0.88); C62(0.88)	LDD0851	[11]
LDCM0254	AC135	HEK-293T	C295(0.97); C62(0.97)	LDD0852	[11]
LDCM0255	AC136	HEK-293T	C295(1.15); C62(1.15)	LDD0853	[11]
LDCM0256	AC137	HEK-293T	C295(0.99); C62(0.99)	LDD0854	[11]
LDCM0257	AC138	HEK-293T	C295(0.69); C62(0.69)	LDD0855	[11]
LDCM0258	AC139	HEK-293T	C295(0.87); C62(0.87)	LDD0856	[11]
LDCM0259	AC14	HEK-293T	C297(1.11); C295(0.81); C62(0.81)	LDD0857	[11]
LDCM0260	AC140	HEK-293T	C295(1.06); C62(1.06)	LDD0858	[11]
LDCM0261	AC141	HEK-293T	C295(0.97); C62(0.97)	LDD0859	[11]
LDCM0262	AC142	HEK-293T	C295(0.69); C62(0.69)	LDD0860	[11]
LDCM0263	AC143	HEK-293T	C295(1.08); C62(1.08)	LDD0861	[11]
LDCM0264	AC144	HEK-293T	C295(0.85); C62(0.85)	LDD0862	[11]
LDCM0265	AC145	HEK-293T	C295(0.94); C62(0.94)	LDD0863	[11]
LDCM0266	AC146	HEK-293T	C295(1.02); C62(1.02)	LDD0864	[11]
LDCM0267	AC147	HEK-293T	C295(0.87); C62(0.87)	LDD0865	[11]
LDCM0268	AC148	HEK-293T	C295(0.93); C62(0.93)	LDD0866	[11]
LDCM0269	AC149	HEK-293T	C295(0.92); C62(0.92)	LDD0867	[11]
LDCM0270	AC15	HEK-293T	C297(1.24); C295(0.68); C62(0.68)	LDD0868	[11]
LDCM0271	AC150	HEK-293T	C295(0.90); C62(0.90)	LDD0869	[11]
LDCM0272	AC151	HEK-293T	C295(0.83); C62(0.83)	LDD0870	[11]
LDCM0273	AC152	HEK-293T	C295(1.19); C62(1.19)	LDD0871	[11]
LDCM0274	AC153	HEK-293T	C295(0.87); C62(0.87)	LDD0872	[11]
LDCM0621	AC154	HEK-293T	C295(0.87); C62(0.87)	LDD2162	[11]
LDCM0622	AC155	HEK-293T	C295(0.92); C62(0.92)	LDD2163	[11]
LDCM0623	AC156	HEK-293T	C295(0.94); C62(0.94)	LDD2164	[11]
LDCM0624	AC157	HEK-293T	C295(1.01); C62(1.01)	LDD2165	[11]
LDCM0276	AC17	HEK-293T	C297(1.17)	LDD0874	[11]
LDCM0277	AC18	HEK-293T	C297(1.29)	LDD0875	[11]
LDCM0278	AC19	HEK-293T	C297(1.14)	LDD0876	[11]
LDCM0279	AC2	HEK-293T	C295(0.96); C62(0.96)	LDD0877	[11]
LDCM0280	AC20	HEK-293T	C297(1.19)	LDD0878	[11]
LDCM0281	AC21	HEK-293T	C297(1.45)	LDD0879	[11]
LDCM0282	AC22	HEK-293T	C297(0.97)	LDD0880	[11]
LDCM0283	AC23	HEK-293T	C297(1.67)	LDD0881	[11]
LDCM0284	AC24	HEK-293T	C297(0.92)	LDD0882	[11]
LDCM0285	AC25	HEK-293T	C297(0.87)	LDD0883	[11]
LDCM0286	AC26	HEK-293T	C297(1.09)	LDD0884	[11]
LDCM0287	AC27	HEK-293T	C297(1.19)	LDD0885	[11]
LDCM0288	AC28	HEK-293T	C297(2.16)	LDD0886	[11]
LDCM0289	AC29	HEK-293T	C297(1.36)	LDD0887	[11]
LDCM0290	AC3	HEK-293T	C295(1.09); C62(1.09)	LDD0888	[11]
LDCM0291	AC30	HEK-293T	C297(1.31)	LDD0889	[11]
LDCM0292	AC31	HEK-293T	C297(1.27)	LDD0890	[11]
LDCM0293	AC32	HEK-293T	C297(1.03)	LDD0891	[11]
LDCM0294	AC33	HEK-293T	C297(1.04)	LDD0892	[11]
LDCM0295	AC34	HEK-293T	C297(1.35)	LDD0893	[11]
LDCM0296	AC35	HEK-293T	C297(0.74); C295(0.74)	LDD0894	[11]
LDCM0297	AC36	HEK-293T	C297(0.57); C295(0.57)	LDD0895	[11]
LDCM0298	AC37	HEK-293T	C297(0.74); C295(0.74)	LDD0896	[11]
LDCM0299	AC38	HEK-293T	C297(0.57); C295(0.57)	LDD0897	[11]
LDCM0300	AC39	HEK-293T	C297(1.20); C295(1.20)	LDD0898	[11]
LDCM0301	AC4	HEK-293T	C295(1.12); C62(1.12)	LDD0899	[11]
LDCM0302	AC40	HEK-293T	C297(0.76); C295(0.76)	LDD0900	[11]
LDCM0303	AC41	HEK-293T	C297(0.71); C295(0.71)	LDD0901	[11]
LDCM0304	AC42	HEK-293T	C297(0.75); C295(0.75)	LDD0902	[11]
LDCM0305	AC43	HEK-293T	C297(0.67); C295(0.67)	LDD0903	[11]
LDCM0306	AC44	HEK-293T	C297(0.81); C295(0.81)	LDD0904	[11]
LDCM0307	AC45	HEK-293T	C297(0.91); C295(0.91)	LDD0905	[11]
LDCM0308	AC46	HEK-293T	C297(0.79); C295(0.97); C62(0.97)	LDD0906	[11]
LDCM0309	AC47	HEK-293T	C297(0.86); C295(1.15); C62(1.15)	LDD0907	[11]
LDCM0310	AC48	HEK-293T	C297(0.86); C295(0.98); C62(0.98)	LDD0908	[11]
LDCM0311	AC49	HEK-293T	C297(1.21); C295(1.13); C62(1.13)	LDD0909	[11]
LDCM0312	AC5	HEK-293T	C295(1.02); C62(1.02)	LDD0910	[11]
LDCM0313	AC50	HEK-293T	C297(0.95); C295(0.91); C62(0.91)	LDD0911	[11]
LDCM0314	AC51	HEK-293T	C297(1.22); C295(0.98); C62(0.98)	LDD0912	[11]
LDCM0315	AC52	HEK-293T	C297(1.01); C295(0.98); C62(0.98)	LDD0913	[11]
LDCM0316	AC53	HEK-293T	C297(1.08); C295(0.97); C62(0.97)	LDD0914	[11]
LDCM0317	AC54	HEK-293T	C297(1.00); C295(1.00); C62(1.00)	LDD0915	[11]
LDCM0318	AC55	HEK-293T	C297(1.02); C295(0.80); C62(0.80)	LDD0916	[11]
LDCM0319	AC56	HEK-293T	C297(0.91); C295(0.93); C62(0.93)	LDD0917	[11]
LDCM0320	AC57	HEK-293T	C295(0.71); C62(0.71)	LDD0918	[11]
LDCM0321	AC58	HEK-293T	C295(0.79); C62(0.79)	LDD0919	[11]
LDCM0322	AC59	HEK-293T	C295(1.06); C62(1.06)	LDD0920	[11]
LDCM0323	AC6	HEK-293T	C297(0.99); C295(0.99); C62(0.99)	LDD0921	[11]
LDCM0324	AC60	HEK-293T	C295(3.17); C62(3.17)	LDD0922	[11]
LDCM0325	AC61	HEK-293T	C295(1.20); C62(1.20)	LDD0923	[11]
LDCM0326	AC62	HEK-293T	C295(0.89); C62(0.89)	LDD0924	[11]
LDCM0327	AC63	HEK-293T	C295(0.81); C62(0.81)	LDD0925	[11]
LDCM0328	AC64	HEK-293T	C295(0.77); C62(0.77)	LDD0926	[11]
LDCM0329	AC65	HEK-293T	C295(0.80); C62(0.80)	LDD0927	[11]
LDCM0330	AC66	HEK-293T	C295(0.80); C62(0.80)	LDD0928	[11]
LDCM0331	AC67	HEK-293T	C295(0.74); C62(0.74)	LDD0929	[11]
LDCM0334	AC7	HEK-293T	C297(1.02); C295(0.62); C62(0.62)	LDD0932	[11]
LDCM0345	AC8	HEK-293T	C297(1.51); C295(0.71); C62(0.71)	LDD0943	[11]
LDCM0349	AC83	HEK-293T	C295(0.86); C62(0.86)	LDD0947	[11]
LDCM0350	AC84	HEK-293T	C295(0.86); C62(0.86)	LDD0948	[11]
LDCM0351	AC85	HEK-293T	C295(0.68); C62(0.68)	LDD0949	[11]
LDCM0352	AC86	HEK-293T	C295(0.72); C62(0.72)	LDD0950	[11]
LDCM0353	AC87	HEK-293T	C295(0.76); C62(0.76)	LDD0951	[11]
LDCM0354	AC88	HEK-293T	C295(0.65); C62(0.65)	LDD0952	[11]
LDCM0355	AC89	HEK-293T	C295(1.24); C62(1.24)	LDD0953	[11]
LDCM0357	AC90	HEK-293T	C295(0.61); C62(0.61)	LDD0955	[11]
LDCM0358	AC91	HEK-293T	C295(0.57); C62(0.57)	LDD0956	[11]
LDCM0359	AC92	HEK-293T	C295(0.62); C62(0.62)	LDD0957	[11]
LDCM0360	AC93	HEK-293T	C295(1.01); C62(1.01)	LDD0958	[11]
LDCM0361	AC94	HEK-293T	C295(0.62); C62(0.62)	LDD0959	[11]
LDCM0362	AC95	HEK-293T	C295(0.65); C62(0.65)	LDD0960	[11]
LDCM0363	AC96	HEK-293T	C295(0.80); C62(0.80)	LDD0961	[11]
LDCM0364	AC97	HEK-293T	C295(0.62); C62(0.62)	LDD0962	[11]
LDCM0365	AC98	HEK-293T	C295(0.91); C62(0.91)	LDD0963	[11]
LDCM0366	AC99	HEK-293T	C295(0.91); C62(0.91)	LDD0964	[11]
LDCM0248	AKOS034007472	HEK-293T	C297(1.16); C295(0.96); C62(0.96)	LDD0846	[11]
LDCM0356	AKOS034007680	HEK-293T	C297(1.20); C295(0.81); C62(0.81)	LDD0954	[11]
LDCM0275	AKOS034007705	HEK-293T	C297(1.51); C295(0.72); C62(0.72)	LDD0873	[11]
LDCM0156	Aniline	NCI-H1299	11.99	LDD0403	[2]
LDCM0088	C45	HEK-293T	17.93	LDD0201	[6]
LDCM0367	CL1	HEK-293T	C297(4.96); C295(0.40); C62(0.40)	LDD0965	[11]
LDCM0368	CL10	HEK-293T	C297(3.86); C295(0.72); C62(0.72)	LDD0966	[11]
LDCM0369	CL100	HEK-293T	C295(0.94); C62(0.94)	LDD0967	[11]
LDCM0370	CL101	HEK-293T	C297(2.10); C295(0.87); C62(0.87)	LDD0968	[11]
LDCM0371	CL102	HEK-293T	C297(1.55); C295(0.70); C62(0.70)	LDD0969	[11]
LDCM0372	CL103	HEK-293T	C297(1.39); C295(0.75); C62(0.75)	LDD0970	[11]
LDCM0373	CL104	HEK-293T	C297(1.33); C295(0.83); C62(0.83)	LDD0971	[11]
LDCM0374	CL105	HEK-293T	C297(0.87)	LDD0972	[11]
LDCM0375	CL106	HEK-293T	C297(0.83)	LDD0973	[11]
LDCM0376	CL107	HEK-293T	C297(1.12)	LDD0974	[11]
LDCM0377	CL108	HEK-293T	C297(0.96)	LDD0975	[11]
LDCM0378	CL109	HEK-293T	C297(1.09)	LDD0976	[11]
LDCM0379	CL11	HEK-293T	C297(2.86); C295(0.70); C62(0.70)	LDD0977	[11]
LDCM0380	CL110	HEK-293T	C297(1.31)	LDD0978	[11]
LDCM0381	CL111	HEK-293T	C297(1.32)	LDD0979	[11]
LDCM0382	CL112	HEK-293T	C297(1.51)	LDD0980	[11]
LDCM0383	CL113	HEK-293T	C297(1.32)	LDD0981	[11]
LDCM0384	CL114	HEK-293T	C297(1.75)	LDD0982	[11]
LDCM0385	CL115	HEK-293T	C297(1.57)	LDD0983	[11]
LDCM0386	CL116	HEK-293T	C297(1.24)	LDD0984	[11]
LDCM0387	CL117	HEK-293T	C297(0.89); C295(0.89)	LDD0985	[11]
LDCM0388	CL118	HEK-293T	C297(0.66); C295(0.66)	LDD0986	[11]
LDCM0389	CL119	HEK-293T	C297(0.78); C295(0.78)	LDD0987	[11]
LDCM0390	CL12	HEK-293T	C297(2.40); C295(1.01); C62(1.01)	LDD0988	[11]
LDCM0391	CL120	HEK-293T	C297(0.96); C295(0.96)	LDD0989	[11]
LDCM0392	CL121	HEK-293T	C297(1.28); C295(0.75); C62(0.75)	LDD0990	[11]
LDCM0393	CL122	HEK-293T	C297(1.05); C295(1.13); C62(1.13)	LDD0991	[11]
LDCM0394	CL123	HEK-293T	C297(1.91); C295(1.16); C62(1.16)	LDD0992	[11]
LDCM0395	CL124	HEK-293T	C297(1.20); C295(0.80); C62(0.80)	LDD0993	[11]
LDCM0396	CL125	HEK-293T	C295(1.03); C62(1.03)	LDD0994	[11]
LDCM0397	CL126	HEK-293T	C295(0.96); C62(0.96)	LDD0995	[11]
LDCM0398	CL127	HEK-293T	C295(0.75); C62(0.75)	LDD0996	[11]
LDCM0399	CL128	HEK-293T	C295(1.17); C62(1.17)	LDD0997	[11]
LDCM0400	CL13	HEK-293T	C297(1.72); C295(0.70); C62(0.70)	LDD0998	[11]
LDCM0401	CL14	HEK-293T	C297(2.20); C295(0.78); C62(0.78)	LDD0999	[11]
LDCM0402	CL15	HEK-293T	C297(2.64); C295(0.64); C62(0.64)	LDD1000	[11]
LDCM0403	CL16	HEK-293T	C152(0.98); C62(0.95)	LDD1607	[23]
LDCM0404	CL17	HEK-293T	C152(1.09); C62(1.19)	LDD1608	[23]
LDCM0405	CL18	HEK-293T	C152(1.06); C62(1.00)	LDD1609	[23]
LDCM0406	CL19	HEK-293T	C152(1.24); C62(0.84)	LDD1610	[23]
LDCM0407	CL2	HEK-293T	C297(2.34); C295(0.62); C62(0.62)	LDD1005	[11]
LDCM0408	CL20	HEK-293T	C152(1.13); C62(0.97)	LDD1612	[23]
LDCM0409	CL21	HEK-293T	C152(1.12); C62(1.04)	LDD1613	[23]
LDCM0410	CL22	HEK-293T	C152(1.04); C62(1.12)	LDD1614	[23]
LDCM0411	CL23	HEK-293T	C152(1.07); C62(0.86)	LDD1615	[23]
LDCM0412	CL24	HEK-293T	C152(1.09); C62(0.98)	LDD1616	[23]
LDCM0413	CL25	HEK-293T	C152(1.14); C62(0.99)	LDD1617	[23]
LDCM0414	CL26	HEK-293T	C152(1.04); C62(1.02)	LDD1618	[23]
LDCM0415	CL27	HEK-293T	C152(0.96); C62(0.92)	LDD1619	[23]
LDCM0416	CL28	HEK-293T	C152(1.00); C62(1.06)	LDD1620	[23]
LDCM0417	CL29	HEK-293T	C152(1.06); C62(1.06)	LDD1621	[23]
LDCM0418	CL3	HEK-293T	C297(2.50); C295(1.25); C62(1.25)	LDD1016	[11]
LDCM0419	CL30	HEK-293T	C152(1.05); C62(0.93)	LDD1623	[23]
LDCM0420	CL31	HEK-293T	C297(1.16); C295(0.72); C62(0.72)	LDD1018	[11]
LDCM0421	CL32	HEK-293T	C297(2.81); C295(0.83); C62(0.83)	LDD1019	[11]
LDCM0422	CL33	HEK-293T	C297(2.45); C295(0.58); C62(0.58)	LDD1020	[11]
LDCM0423	CL34	HEK-293T	C297(1.72); C295(1.01); C62(1.01)	LDD1021	[11]
LDCM0424	CL35	HEK-293T	C297(2.17); C295(0.75); C62(0.75)	LDD1022	[11]
LDCM0425	CL36	HEK-293T	C297(1.73); C295(0.90); C62(0.90)	LDD1023	[11]
LDCM0426	CL37	HEK-293T	C297(2.12); C295(1.05); C62(1.05)	LDD1024	[11]
LDCM0428	CL39	HEK-293T	C297(1.76); C295(0.80); C62(0.80)	LDD1026	[11]
LDCM0429	CL4	HEK-293T	C297(1.80); C295(0.79); C62(0.79)	LDD1027	[11]
LDCM0430	CL40	HEK-293T	C297(1.95); C295(1.15); C62(1.15)	LDD1028	[11]
LDCM0431	CL41	HEK-293T	C297(2.20); C295(0.87); C62(0.87)	LDD1029	[11]
LDCM0432	CL42	HEK-293T	C297(1.78); C295(0.88); C62(0.88)	LDD1030	[11]
LDCM0433	CL43	HEK-293T	C297(1.69); C295(0.87); C62(0.87)	LDD1031	[11]
LDCM0434	CL44	HEK-293T	C297(1.81); C295(0.78); C62(0.78)	LDD1032	[11]
LDCM0435	CL45	HEK-293T	C297(2.12); C295(0.84); C62(0.84)	LDD1033	[11]
LDCM0436	CL46	HEK-293T	C295(1.44); C62(1.44)	LDD1034	[11]
LDCM0437	CL47	HEK-293T	C295(1.44); C62(1.44)	LDD1035	[11]
LDCM0438	CL48	HEK-293T	C295(1.60); C62(1.60)	LDD1036	[11]
LDCM0439	CL49	HEK-293T	C295(1.16); C62(1.16)	LDD1037	[11]
LDCM0440	CL5	HEK-293T	C297(2.37); C295(0.77); C62(0.77)	LDD1038	[11]
LDCM0441	CL50	HEK-293T	C295(1.24); C62(1.24)	LDD1039	[11]
LDCM0442	CL51	HEK-293T	C295(1.44); C62(1.44)	LDD1040	[11]
LDCM0443	CL52	HEK-293T	C295(0.86); C62(0.86)	LDD1041	[11]
LDCM0444	CL53	HEK-293T	C295(0.87); C62(0.87)	LDD1042	[11]
LDCM0445	CL54	HEK-293T	C295(1.46); C62(1.46)	LDD1043	[11]
LDCM0446	CL55	HEK-293T	C295(1.23); C62(1.23)	LDD1044	[11]
LDCM0447	CL56	HEK-293T	C295(0.91); C62(0.91)	LDD1045	[11]
LDCM0448	CL57	HEK-293T	C295(1.05); C62(1.05)	LDD1046	[11]
LDCM0449	CL58	HEK-293T	C295(1.33); C62(1.33)	LDD1047	[11]
LDCM0450	CL59	HEK-293T	C295(0.83); C62(0.83)	LDD1048	[11]
LDCM0451	CL6	HEK-293T	C297(1.83); C295(0.63); C62(0.63)	LDD1049	[11]
LDCM0452	CL60	HEK-293T	C295(1.20); C62(1.20)	LDD1050	[11]
LDCM0453	CL61	HEK-293T	C295(0.98); C62(0.98)	LDD1051	[11]
LDCM0454	CL62	HEK-293T	C295(1.23); C62(1.23)	LDD1052	[11]
LDCM0455	CL63	HEK-293T	C295(1.00); C62(1.00)	LDD1053	[11]
LDCM0456	CL64	HEK-293T	C295(0.80); C62(0.80)	LDD1054	[11]
LDCM0457	CL65	HEK-293T	C295(1.17); C62(1.17)	LDD1055	[11]
LDCM0458	CL66	HEK-293T	C295(1.26); C62(1.26)	LDD1056	[11]
LDCM0459	CL67	HEK-293T	C295(1.46); C62(1.46)	LDD1057	[11]
LDCM0460	CL68	HEK-293T	C295(1.23); C62(1.23)	LDD1058	[11]
LDCM0461	CL69	HEK-293T	C295(0.86); C62(0.86)	LDD1059	[11]
LDCM0462	CL7	HEK-293T	C297(2.16); C295(0.61); C62(0.61)	LDD1060	[11]
LDCM0463	CL70	HEK-293T	C295(0.94); C62(0.94)	LDD1061	[11]
LDCM0464	CL71	HEK-293T	C295(0.95); C62(0.95)	LDD1062	[11]
LDCM0465	CL72	HEK-293T	C295(1.07); C62(1.07)	LDD1063	[11]
LDCM0466	CL73	HEK-293T	C295(0.83); C62(0.83)	LDD1064	[11]
LDCM0467	CL74	HEK-293T	C295(1.11); C62(1.11)	LDD1065	[11]
LDCM0469	CL76	HEK-293T	C152(1.00); C62(0.99)	LDD1672	[23]
LDCM0470	CL77	HEK-293T	C152(1.08); C62(1.07)	LDD1673	[23]
LDCM0471	CL78	HEK-293T	C152(1.04); C62(0.93)	LDD1674	[23]
LDCM0472	CL79	HEK-293T	C152(1.01); C62(0.86)	LDD1675	[23]
LDCM0473	CL8	HEK-293T	C297(0.52); C295(1.03); C62(1.53)	LDD1071	[11]
LDCM0474	CL80	HEK-293T	C152(1.11); C62(1.02)	LDD1677	[23]
LDCM0475	CL81	HEK-293T	C152(1.00); C62(0.94)	LDD1678	[23]
LDCM0476	CL82	HEK-293T	C152(1.10); C62(1.14)	LDD1679	[23]
LDCM0477	CL83	HEK-293T	C152(1.05); C62(0.92)	LDD1680	[23]
LDCM0478	CL84	HEK-293T	C152(1.00); C62(1.20)	LDD1681	[23]
LDCM0479	CL85	HEK-293T	C152(0.81); C62(0.84)	LDD1682	[23]
LDCM0480	CL86	HEK-293T	C152(0.79); C62(1.01)	LDD1683	[23]
LDCM0481	CL87	HEK-293T	C152(0.77); C62(0.87)	LDD1684	[23]
LDCM0482	CL88	HEK-293T	C152(0.84); C62(0.89)	LDD1685	[23]
LDCM0483	CL89	HEK-293T	C152(0.85); C62(1.09)	LDD1686	[23]
LDCM0484	CL9	HEK-293T	C297(0.70); C295(0.95); C62(1.04)	LDD1082	[11]
LDCM0485	CL90	HEK-293T	C152(1.19); C62(1.17)	LDD1688	[23]
LDCM0486	CL91	HEK-293T	C295(1.16); C62(1.16)	LDD1084	[11]
LDCM0487	CL92	HEK-293T	C295(0.91); C62(0.91)	LDD1085	[11]
LDCM0488	CL93	HEK-293T	C295(0.96); C62(0.96)	LDD1086	[11]
LDCM0489	CL94	HEK-293T	C295(0.84); C62(0.84)	LDD1087	[11]
LDCM0490	CL95	HEK-293T	C295(0.70); C62(0.70)	LDD1088	[11]
LDCM0491	CL96	HEK-293T	C295(0.82); C62(0.82)	LDD1089	[11]
LDCM0492	CL97	HEK-293T	C295(0.88); C62(0.88)	LDD1090	[11]
LDCM0493	CL98	HEK-293T	C295(0.79); C62(0.79)	LDD1091	[11]
LDCM0494	CL99	HEK-293T	C295(0.97); C62(0.97)	LDD1092	[11]
LDCM0189	Compound 16	HEK-293T	21.51	LDD0492	[18]
LDCM0185	Compound 17	HEK-293T	10.93	LDD0504	[18]
LDCM0182	Compound 18	HEK-293T	7.27	LDD0501	[18]
LDCM0184	Compound 20	HEK-293T	16.13	LDD0503	[18]
LDCM0191	Compound 21	HEK-293T	18.18	LDD0493	[18]
LDCM0186	Compound 31	HEK-293T	9.80	LDD0506	[18]
LDCM0187	Compound 32	HEK-293T	21.28	LDD0507	[18]
LDCM0188	Compound 33	HEK-293T	10.58	LDD0505	[18]
LDCM0190	Compound 34	HEK-293T	16.67	LDD0497	[18]
LDCM0192	Compound 35	HEK-293T	14.39	LDD0491	[18]
LDCM0194	Compound 37	HEK-293T	19.23	LDD0498	[18]
LDCM0195	Compound 38	HEK-293T	26.67	LDD0499	[18]
LDCM0196	Compound 39	HEK-293T	15.63	LDD0496	[18]
LDCM0197	Compound 40	HEK-293T	14.29	LDD0495	[18]
LDCM0181	Compound 41	HEK-293T	9.51	LDD0502	[18]
LDCM0183	Compound 42	HEK-293T	3.38	LDD0500	[18]
LDCM0495	E2913	HEK-293T	C152(0.95); C62(0.90)	LDD1698	[23]
LDCM0175	Ethacrynic acid	HeLa	N.A.	LDD0440	[10]
LDCM0625	F8	Ramos	C152(1.17)	LDD2187	[24]
LDCM0572	Fragment10	Ramos	C152(3.28)	LDD2189	[24]
LDCM0573	Fragment11	Ramos	C152(1.01)	LDD2190	[24]
LDCM0574	Fragment12	Ramos	C152(1.45)	LDD2191	[24]
LDCM0575	Fragment13	Ramos	C152(1.32)	LDD2192	[24]
LDCM0576	Fragment14	Ramos	C152(3.43)	LDD2193	[24]
LDCM0580	Fragment21	Ramos	C152(1.87)	LDD2195	[24]
LDCM0582	Fragment23	Ramos	C152(2.01)	LDD2196	[24]
LDCM0578	Fragment27	Ramos	C152(1.18)	LDD2197	[24]
LDCM0586	Fragment28	Ramos	C152(0.73)	LDD2198	[24]
LDCM0588	Fragment30	Ramos	C152(1.95)	LDD2199	[24]
LDCM0589	Fragment31	Ramos	C152(1.88)	LDD2200	[24]
LDCM0590	Fragment32	Ramos	C152(3.81)	LDD2201	[24]
LDCM0468	Fragment33	HEK-293T	C295(1.00); C62(1.00)	LDD1066	[11]
LDCM0596	Fragment38	Ramos	C152(3.07)	LDD2203	[24]
LDCM0566	Fragment4	Ramos	C152(1.69)	LDD2184	[24]
LDCM0427	Fragment51	HEK-293T	C297(1.66); C295(1.28); C62(1.28)	LDD1025	[11]
LDCM0610	Fragment52	Ramos	C152(2.05)	LDD2204	[24]
LDCM0614	Fragment56	Ramos	C152(1.56)	LDD2205	[24]
LDCM0569	Fragment7	Ramos	C152(2.48)	LDD2186	[24]
LDCM0073	Kambe_cp3	PC-3	6.01	LDD0128	[19]
LDCM0079	kambe_cp64	PC-3	2.67	LDD0135	[19]
LDCM0022	KB02	HEK-293T	C152(0.94)	LDD1492	[23]
LDCM0023	KB03	HEK-293T	C152(0.93)	LDD1497	[23]
LDCM0024	KB05	HEK-293T	C152(0.87)	LDD1502	[23]
LDCM0506	Nucleophilic fragment 16a	MDA-MB-231	C152(1.36)	LDD2099	[7]
LDCM0514	Nucleophilic fragment 20a	MDA-MB-231	C152(0.85)	LDD2107	[7]
LDCM0518	Nucleophilic fragment 22a	MDA-MB-231	C152(1.22)	LDD2111	[7]
LDCM0526	Nucleophilic fragment 26a	MDA-MB-231	C152(1.89)	LDD2119	[7]
LDCM0530	Nucleophilic fragment 28a	MDA-MB-231	C152(1.04)	LDD2123	[7]
LDCM0534	Nucleophilic fragment 30a	MDA-MB-231	C152(0.98)	LDD2127	[7]
LDCM0536	Nucleophilic fragment 31	MDA-MB-231	C152(1.20)	LDD2129	[7]
LDCM0542	Nucleophilic fragment 37	MDA-MB-231	C152(1.33)	LDD2135	[7]
LDCM0543	Nucleophilic fragment 38	MDA-MB-231	C152(1.47)	LDD2136	[7]
LDCM0544	Nucleophilic fragment 39	MDA-MB-231	C152(0.93)	LDD2137	[7]
LDCM0546	Nucleophilic fragment 40	MDA-MB-231	C152(1.28)	LDD2140	[7]
LDCM0552	Nucleophilic fragment 6a	MDA-MB-231	C152(1.11)	LDD2146	[7]
LDCM0628	OTUB2-COV-1	HEK-293T	C152(1.02)	LDD2207	[25]
LDCM0099	Phenelzine	MDA-MB-231	4.00	LDD0388	[3]
LDCM0131	RA190	MM1.R	C152(1.54)	LDD0304	[26]
LDCM0008	Tranylcypromine	SH-SY5Y	5.29	LDD0054	[8]

The Interaction Atlas With This Target

The Drug(s) Related To This Target

Investigative

Click To Hide/Show 1 Drug(s) Interacting with This Target

Drug Name				Drug Type	External ID
L-benzylsuccinic Acid				.	DB07506

References

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3	Hydrazines as versatile chemical biology probes and drug-discovery tools for cofactor-dependent enzymes. bioRxiv, 2020-06.
4	Low-Toxicity Sulfonium-Based Probes for Cysteine-Specific Profiling in Live Cells. Anal Chem. 2022 Mar 15;94(10):4366-4372. doi: 10.1021/acs.analchem.1c05129. Epub 2022 Mar 4.
5	Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
6	Discovery of Potent and Selective Inhibitors against Protein-Derived Electrophilic Cofactors. J Am Chem Soc. 2022 Mar 30;144(12):5377-5388. doi: 10.1021/jacs.1c12748. Epub 2022 Mar 2.
7	Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29. Mass spectrometry data entry: PXD039908 , PXD029761
8	Tranylcypromine specificity for monoamine oxidase is limited by promiscuous protein labelling and lysosomal trapping. RSC Chem Biol. 2020 Aug 12;1(4):209-213. doi: 10.1039/d0cb00048e. eCollection 2020 Oct 1. Mass spectrometry data entry: PXD018580
9	Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z. Mass spectrometry data entry: PXD044625
10	Chemoproteomic Profiling Reveals Ethacrynic Acid Targets Adenine Nucleotide Translocases to Impair Mitochondrial Function. Mol Pharm. 2018 Jun 4;15(6):2413-2422. doi: 10.1021/acs.molpharmaceut.8b00250. Epub 2018 May 15.
11	Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
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13	A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21. Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
14	Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24. Mass spectrometry data entry: PXD029255
15	DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22. Mass spectrometry data entry: PXD033004
16	Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
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18	Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
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20	Evaluation of fully-functionalized diazirine tags for chemical proteomic applications. Chem Sci. 2021 May 7;12(22):7839-7847. doi: 10.1039/d1sc01360b. Mass spectrometry data entry: PXD025652
21	Cell-based proteome profiling of potential dasatinib targets by use of affinity-based probes. J Am Chem Soc. 2012 Feb 15;134(6):3001-14. doi: 10.1021/ja208518u. Epub 2012 Feb 1.
22	Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20. Mass spectrometry data entry: PXD007570
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26	Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.

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Correspondence

Prof. Feng Zhu

Prof. Feng Ni