General Information of Probe

Probe ID
LDPC0263
Probe Name
FFF probe9
Synonyms
SCHEMBL20400218
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 324.4
Lipid-water partition coefficient (xlogp) 2.4
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C19H24N4O
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-(4-piperidin-4-ylphenyl)propanamide
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)NC2=CC=C(C=C2)C3CCNCC3
InChI
InChI=1S/C19H24N4O/c1-2-3-11-19(22-23-19)12-8-18(24)21-17-6-4-15(5-7-17)16-9-13-20-14-10-16/h1,4-7,16,20H,3,8-14H2,(H,21,24)
InChIKey
HEODGZWKMIEEEO-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

109 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 20.00  LDD0485 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 20.00  LDD0470 
Acid ceramidase (ASAH1) LDTP05905 20.00  LDD0470 
ADP-ribosylation factor 5 (ARF5) LDTP05193 5.63  LDD0470 
Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) LDTP03560 12.55  LDD0470 
Alpha-galactosidase A (GLA) LDTP02141 20.00  LDD0470 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 20.00  LDD0470 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 15.98  LDD0470 
Aspartyl/asparaginyl beta-hydroxylase (ASPH) LDTP05652 20.00  LDD0470 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 5.67  LDD0470 
ATP-binding cassette sub-family D member 3 (ABCD3) LDTP03424 6.38  LDD0470 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 7.38  LDD0470 
Beta-galactosidase (GLB1) LDTP02837 20.00  LDD0470 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 20.00  LDD0470 
Beta-hexosaminidase subunit beta (HEXB) LDTP02216 20.00  LDD0470 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 20.00  LDD0470 
Bleomycin hydrolase (BLMH) LDTP05992 12.30  LDD0470 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 6.04  LDD0485 
Calpain-2 catalytic subunit (CAPN2) LDTP02911 20.00  LDD0470 
Carboxypeptidase D (CPD) LDTP01372 20.00  LDD0470 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 8.81  LDD0470 
Catalase (CAT) LDTP02001 20.00  LDD0470 
Cathepsin B (CTSB) LDTP02223 20.00  LDD0470 
Cathepsin D (CTSD) LDTP02198 20.00  LDD0470 
Creatine kinase U-type, mitochondrial (CKMT1A; CKMT1B) LDTP02622 6.57  LDD0470 
Cytochrome b5 type B (CYB5B) LDTP00697 20.00  LDD0470 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 18.76  LDD0470 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 6.66  LDD0470 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 6.01  LDD0470 
Delta(24)-sterol reductase (DHCR24) LDTP06375 9.79  LDD0470 
Deoxyribonuclease-2-alpha (DNASE2) LDTP00185 20.00  LDD0470 
Dermcidin (DCD) LDTP05171 20.00  LDD0470 
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) LDTP02362 20.00  LDD0470 
Dipeptidyl peptidase 1 (CTSC) LDTP04572 20.00  LDD0470 
DnaJ homolog subfamily C member 10 (DNAJC10) LDTP08590 6.03  LDD0470 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 12.03  LDD0470 
E3 ubiquitin-protein ligase Itchy homolog (ITCH) LDTP10441 20.00  LDD0470 
E3 UFM1-protein ligase 1 (UFL1) LDTP01444 20.00  LDD0470 
Elongation factor G, mitochondrial (GFM1) LDTP10774 12.35  LDD0470 
Endoplasmic reticulum chaperone BiP (HSPA5) LDTP02534 13.58  LDD0470 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 18.30  LDD0470 
Epididymis-specific alpha-mannosidase (MAN2B2) LDTP13853 20.00  LDD0470 
Epoxide hydrolase 1 (EPHX1) LDTP02175 17.23  LDD0470 
Exonuclease 1 (EXO1) LDTP13751 9.64  LDD0470 
Gamma-glutamyl hydrolase (GGH) LDTP09886 20.00  LDD0470 
Glucosidase 2 subunit beta (PRKCSH) LDTP02718 8.02  LDD0470 
Heme oxygenase 2 (HMOX2) LDTP03540 20.00  LDD0485 
Hexokinase-2 (HK2) LDTP04531 5.22  LDD0470 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 20.00  LDD0470 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 5.96  LDD0470 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 5.62  LDD0485 
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) LDTP04211 6.39  LDD0470 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 10.65  LDD0470 
Lanosterol synthase (LSS) LDTP04183 20.00  LDD0485 
Legumain (LGMN) LDTP10888 20.00  LDD0470 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 20.00  LDD0470 
Lon protease homolog, mitochondrial (LONP1) LDTP03817 13.45  LDD0470 
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) LDTP03858 17.92  LDD0470 
Lysosomal acid phosphatase (ACP2) LDTP02539 19.73  LDD0470 
Lysosomal alpha-glucosidase (GAA) LDTP02486 20.00  LDD0470 
Lysosomal alpha-mannosidase (MAN2B1) LDTP00338 20.00  LDD0470 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 13.64  LDD0470 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 20.00  LDD0470 
Mannosyl-oligosaccharide glucosidase (MOGS) LDTP05971 12.90  LDD0470 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 20.00  LDD0470 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 5.10  LDD0470 
NADH-cytochrome b5 reductase 3 (CYB5R3) LDTP01770 13.63  LDD0470 
NADPH--cytochrome P450 reductase (POR) LDTP02848 14.28  LDD0470 
Nardilysin (NRDC) LDTP00886 19.20  LDD0470 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 20.00  LDD0470 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 7.55  LDD0470 
Peroxisomal multifunctional enzyme type 2 (HSD17B4) LDTP04440 6.66  LDD0470 
Phospholipase A2 group XV (PLA2G15) LDTP09088 20.00  LDD0470 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 20.00  LDD0470 
Polypeptide N-acetylgalactosaminyltransferase 2 (GALNT2) LDTP05623 20.00  LDD0470 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 20.00  LDD0470 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 20.00  LDD0470 
Prolyl 3-hydroxylase 1 (P3H1) LDTP06750 20.00  LDD0485 
Prostaglandin reductase 2 (PTGR2) LDTP08979 12.00  LDD0470 
Proteasome subunit beta type-7 (PSMB7) LDTP10862 15.48  LDD0470 
Protein disulfide-isomerase A4 (PDIA4) LDTP02677 12.48  LDD0470 
Protein-glutamine gamma-glutamyltransferase E (TGM3) LDTP05548 20.00  LDD0470 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 9.33  LDD0470 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 20.00  LDD0470 
Ras-related GTP-binding protein C (RRAGC) LDTP12166 7.71  LDD0470 
Ras-related protein Rab-14 (RAB14) LDTP04901 11.72  LDD0470 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 20.00  LDD0470 
Ribonuclease T2 (RNASET2) LDTP00316 20.00  LDD0470 
Ribosomal protein S6 kinase alpha-1 (RPS6KA1) LDTP06384 14.16  LDD0470 
Ribosomal protein S6 kinase alpha-3 (RPS6KA3) LDTP04471 14.46  LDD0470 
RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) LDTP05588 20.00  LDD0485 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 17.05  LDD0470 
Serine hydroxymethyltransferase, cytosolic (SHMT1) LDTP03688 12.94  LDD0470 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 9.83  LDD0470 
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PPP2R5C) LDTP05841 5.66  LDD0470 
Sialate O-acetylesterase (SIAE) LDTP12135 20.00  LDD0470 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 20.00  LDD0470 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 20.00  LDD0470 
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (NSDHL) LDTP06455 5.36  LDD0470 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 5.95  LDD0470 
SUMO-activating enzyme subunit 2 (UBA2) LDTP13156 5.78  LDD0470 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 5.44  LDD0470 
Tissue alpha-L-fucosidase (FUCA1) LDTP02006 20.00  LDD0470 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 20.00  LDD0470 
Ubiquitin thioesterase OTUB1 (OTUB1) LDTP10318 10.52  LDD0470 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 8.50  LDD0470 
Valine--tRNA ligase (VARS1) LDTP03366 20.00  LDD0470 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 9.64  LDD0470 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 5.16  LDD0470 
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⏷ Show the Full List of 109 Enzyme
55 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 20.00  LDD0470 
Amino acid transporter heavy chain SLC3A2 (SLC3A2) LDTP02256 5.30  LDD0470 
Amyloid-beta precursor protein (APP) LDTP02071 20.00  LDD0485 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 7.38  LDD0470 
BOS complex subunit NCLN (NCLN) LDTP10036 12.62  LDD0470 
Calnexin (CANX) LDTP03405 8.07  LDD0470 
Calreticulin (CALR) LDTP03402 7.48  LDD0470 
Complement component 1 Q subcomponent-binding protein, mitochondrial (C1QBP) LDTP05510 8.04  LDD0470 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 20.00  LDD0470 
Desmoplakin (DSP) LDTP02815 20.00  LDD0470 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST) LDTP03870 5.10  LDD0470 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (RPN1) LDTP02057 6.29  LDD0470 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) LDTP02058 18.12  LDD0470 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 8.18  LDD0470 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 20.00  LDD0470 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 20.00  LDD0470 
Importin subunit alpha-1 (KPNA2) LDTP04501 5.64  LDD0470 
Lysosome membrane protein 2 (SCARB2) LDTP06034 20.00  LDD0470 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 20.00  LDD0470 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 5.00  LDD0470 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 13.82  LDD0470 
MICOS complex subunit MIC60 (IMMT) LDTP06660 17.59  LDD0470 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 7.12  LDD0470 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 15.54  LDD0470 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 20.00  LDD0485 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 20.00  LDD0470 
Mitochondrial import receptor subunit TOM40 homolog (TOMM40) LDTP01748 13.21  LDD0470 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 20.00  LDD0470 
Nuclear pore complex protein Nup153 (NUP153) LDTP04309 5.22  LDD0470 
Phosphatidylinositol transfer protein beta isoform (PITPNB) LDTP04213 12.87  LDD0470 
Prosaposin (PSAP) LDTP02215 20.00  LDD0470 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 20.00  LDD0470 
Protein tweety homolog 3 (TTYH3) LDTP11615 20.00  LDD0485 
Proton-activated chloride channel (PACC1) LDTP12042 17.89  LDD0470 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 20.00  LDD0470 
Sideroflexin-1 (SFXN1) LDTP12090 7.92  LDD0470 
Signal recognition particle subunit SRP68 (SRP68) LDTP13262 5.21  LDD0470 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 12.96  LDD0470 
Sorting nexin-1 (SNX1) LDTP05938 5.47  LDD0470 
Stomatin-like protein 2, mitochondrial (STOML2) LDTP13416 5.00  LDD0470 
Surfeit locus protein 4 (SURF4) LDTP00592 20.00  LDD0470 
Syntenin-1 (SDCBP) LDTP00310 19.27  LDD0470 
Transferrin receptor protein 1 (TFRC) LDTP01969 20.00  LDD0470 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 20.00  LDD0470 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 13.71  LDD0470 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 14.57  LDD0470 
Transmembrane protein 160 (TMEM160) LDTP20002 20.00  LDD0470 
Transmembrane protein 33 (TMEM33) LDTP04787 12.91  LDD0470 
Transmembrane protein 87A (TMEM87A) LDTP15481 20.00  LDD0485 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 9.04  LDD0470 
Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 5.49  LDD0470 
Vesicular integral-membrane protein VIP36 (LMAN2) LDTP05690 20.00  LDD0470 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 20.00  LDD0470 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 20.00  LDD0470 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 9.32  LDD0470 
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⏷ Show the Full List of 55 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Y-box-binding protein 1 (YBX1) LDTP05065 11.93  LDD0470 
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1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 20.00  LDD0470 
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68 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acidic leucine-rich nuclear phosphoprotein 32 family member E (ANP32E) LDTP11207 12.86  LDD0470 
Actin-related protein 2 (ACTR2) LDTP04903 11.93  LDD0470 
Alpha-2-macroglobulin (A2M) LDTP01814 20.00  LDD0470 
Amyloid beta precursor like protein 2 (APLP2) LDTP05491 20.00  LDD0485 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 20.00  LDD0485 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 20.00  LDD0485 
Calumenin (CALU) LDTP00887 20.00  LDD0470 
Catenin beta-1 (CTNNB1) LDTP03712 5.04  LDD0470 
Cell cycle and apoptosis regulator protein 2 (CCAR2) LDTP08760 8.54  LDD0470 
Cleavage and polyadenylation specificity factor subunit 6 (CPSF6) LDTP06584 8.16  LDD0470 
Coatomer subunit delta (ARCN1) LDTP04181 5.73  LDD0470 
Crk-like protein (CRKL) LDTP04092 7.05  LDD0470 
Dynactin subunit 1 (DCTN1) LDTP06082 12.28  LDD0470 
Dynactin subunit 2 (DCTN2) LDTP05922 5.53  LDD0470 
Emerin (EMD) LDTP04356 6.06  LDD0470 
Endoplasmin (HSP90B1) LDTP02734 6.22  LDD0470 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 20.00  LDD0470 
Eukaryotic translation initiation factor 4H (EIF4H) LDTP06301 6.17  LDD0470 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 15.45  LDD0470 
FAS-associated factor 2 (FAF2) LDTP10185 5.21  LDD0470 
Galectin-3-binding protein (LGALS3BP) LDTP05558 20.00  LDD0470 
Ganglioside GM2 activator (GM2A) LDTP02927 20.00  LDD0470 
Golgi apparatus protein 1 (GLG1) LDTP09920 20.00  LDD0485 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 20.00  LDD0470 
Golgi membrane protein 1 (GOLM1) LDTP09054 20.00  LDD0470 
Growth factor receptor-bound protein 2 (GRB2) LDTP05035 12.07  LDD0470 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 5.10  LDD0470 
Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 5.06  LDD0470 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 5.83  LDD0470 
Hornerin (HRNR) LDTP08425 20.00  LDD0470 
Junction plakoglobin (JUP) LDTP02756 12.71  LDD0470 
Keratinocyte proline-rich protein (KPRP) LDTP07136 20.00  LDD0470 
KH domain-containing RNA-binding protein QKI (QKI) LDTP10700 12.38  LDD0470 
Kinesin light chain 2 (KLC2) LDTP11695 5.03  LDD0470 
La-related protein 1 (LARP1) LDTP07605 20.00  LDD0470 
Lamin-B2 (LMNB2) LDTP05400 5.63  LDD0470 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 6.16  LDD0470 
Microtubule-associated protein RP/EB family member 1 (MAPRE1) LDTP06444 6.57  LDD0470 
Mitochondrial antiviral-signaling protein (MAVS) LDTP08058 6.03  LDD0470 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 20.00  LDD0470 
Neudesin (NENF) LDTP13630 15.70  LDD0470 
Nicastrin (NCSTN) LDTP09787 20.00  LDD0470 
Nuclear migration protein nudC (NUDC) LDTP13817 5.87  LDD0470 
Nucleobindin-1 (NUCB1) LDTP05375 20.00  LDD0470 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 20.00  LDD0470 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 20.00  LDD0470 
Pregnancy zone protein (PZP) LDTP03071 20.00  LDD0470 
Prelamin-A/C (LMNA) LDTP01932 5.12  LDD0470 
Prohibitin-2 (PHB2) LDTP10924 5.92  LDD0470 
Protein FAM114A2 (FAM114A2) LDTP16080 20.00  LDD0485 
Protein SET (SET) LDTP05277 6.81  LDD0470 
Protein transport protein Sec16A (SEC16A) LDTP00512 13.10  LDD0470 
Reticulocalbin-1 (RCN1) LDTP06352 20.00  LDD0470 
Reticulocalbin-2 (RCN2) LDTP06097 20.00  LDD0470 
RNA-binding motif protein, X chromosome (RBMX) LDTP03850 6.19  LDD0470 
RNA-binding protein FUS (FUS) LDTP03775 5.53  LDD0470 
SERPINE1 mRNA-binding protein 1 (SERBP1) LDTP09081 5.61  LDD0470 
Sister chromatid cohesion protein PDS5 homolog A (PDS5A) LDTP06684 7.14  LDD0470 
Splicing factor 3B subunit 2 (SF3B2) LDTP05870 12.32  LDD0470 
Src substrate cortactin (CTTN) LDTP06094 6.39  LDD0470 
Structural maintenance of chromosomes protein 3 (SMC3) LDTP13760 5.21  LDD0470 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 6.07  LDD0470 
Tetraspanin-6 (TSPAN6) LDTP14458 20.00  LDD0485 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 7.12  LDD0470 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 15.96  LDD0470 
Vimentin (VIM) LDTP02297 9.38  LDD0470 
WD repeat-containing protein 43 (WDR43) LDTP06305 20.00  LDD0470 
Zyxin (ZYX) LDTP06507 5.00  LDD0470 
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⏷ Show the Full List of 68 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:200uM; negative probe:200uM
Quantitative Method
SILAC
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
  
Experiment 2 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:20uM; negative probe:20uM
Quantitative Method
SILAC
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID

References

1 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.