Details of the Target

General Information of Target

Target ID LDTP05862
Target Name NAD(P) transhydrogenase, mitochondrial (NNT)
Gene Name NNT
Gene ID 23530
Synonyms
NAD(P) transhydrogenase, mitochondrial; EC 7.1.1.1; Nicotinamide nucleotide transhydrogenase; Pyridine nucleotide transhydrogenase
3D Structure
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2D Sequence (FASTA)
Download
3D Structure (PDB)
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Sequence
MANLLKTVVTGCSCPLLSNLGSCKGLRVKKDFLRTFYTHQELWCKAPVKPGIPYKQLTVG
VPKEIFQNEKRVALSPAGVQNLVKQGFNVVVESGAGEASKFSDDHYRVAGAQIQGAKEVL
ASDLVVKVRAPMVNPTLGVHEADLLKTSGTLISFIYPAQNPELLNKLSQRKTTVLAMDQV
PRVTIAQGYDALSSMANIAGYKAVVLAANHFGRFFTGQITAAGKVPPAKILIVGGGVAGL
ASAGAAKSMGAIVRGFDTRAAALEQFKSLGAEPLEVDLKESGEGQGGYAKEMSKEFIEAE
MKLFAQQCKEVDILISTALIPGKKAPVLFNKEMIESMKEGSVVVDLAAEAGGNFETTKPG
ELYIHKGITHIGYTDLPSRMATQASTLYSNNITKLLKAISPDKDNFYFDVKDDFDFGTMG
HVIRGTVVMKDGKVIFPAPTPKNIPQGAPVKQKTVAELEAEKAATITPFRKTMSTASAYT
AGLTGILGLGIAAPNLAFSQMVTTFGLAGIVGYHTVWGVTPALHSPLMSVTNAISGLTAV
GGLALMGGHLYPSTTSQGLAALAAFISSVNIAGGFLVTQRMLDMFKRPTDPPEYNYLYLL
PAGTFVGGYLAALYSGYNIEQIMYLGSGLCCVGALAGLSTQGTARLGNALGMIGVAGGLA
ATLGVLKPGPELLAQMSGAMALGGTIGLTIAKRIQISDLPQLVAAFHSLVGLAAVLTCIA
EYIIEYPHFATDAAANLTKIVAYLGTYIGGVTFSGSLIAYGKLQGLLKSAPLLLPGRHLL
NAGLLAASVGGIIPFMVDPSFTTGITCLGSVSALSAVMGVTLTAAIGGADMPVVITVLNS
YSGWALCAEGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGG
KPMEISGTHTEINLDNAIDMIREANSIIITPGYGLCAAKAQYPIADLVKMLTEQGKKVRF
GIHPVAGRMPGQLNVLLAEAGVPYDIVLEMDEINHDFPDTDLVLVIGANDTVNSAAQEDP
NSIIAGMPVLEVWKSKQVIVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAKKTCDALQAKV
RESYQK
Target Type
Literature-reported
Target Bioclass
Enzyme
Family
AlaDH/PNT family; PNT beta subunit family
Subcellular location
Mitochondrion inner membrane
Function
The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland.
TTD ID
T02484
Uniprot ID
Q13423
DrugMap ID
TTKIH76
Ensemble ID
ENST00000264663.9
HGNC ID
HGNC:7863

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 32 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
N1
 Probe Info  		100.00  LDD0242  [1]
TH211
 Probe Info  		Y1084(20.00); Y388(20.00); Y373(18.84); Y933(12.64)  LDD0260  [2]
C-Sul
 Probe Info  		3.17  LDD0066  [3]
YN-1
 Probe Info  		100.00  LDD0444  [4]
STPyne
 Probe Info  		K1042(10.00); K1071(5.23); K171(5.63); K290(10.00)  LDD0277  [5]
BTD
 Probe Info  		C1073(5.15)  LDD1699  [6]
ONAyne
 Probe Info  		K430(10.00)  LDD0275  [5]
Probe 1
 Probe Info  		Y288(409.32)  LDD3495  [7]
DBIA
 Probe Info  		C308(16.54)  LDD0209  [8]
ATP probe
 Probe Info  		K290(0.00); K294(0.00)  LDD0199  [9]
m-APA
 Probe Info  		H140(0.00); H210(0.00)  LDD2231  [10]
4-Iodoacetamidophenylacetylene
 Probe Info  		C936(0.00); C1073(0.00); C308(0.00)  LDD0038  [11]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [12]
Lodoacetamide azide
 Probe Info  		C308(0.00); C1073(0.00); C936(0.00)  LDD0037  [11]
IPM
 Probe Info  		N.A.  LDD0025  [13]
JW-RF-010
 Probe Info  		C936(0.00); C1073(0.00)  LDD0026  [13]
TFBX
 Probe Info  		N.A.  LDD0027  [13]
WYneN
 Probe Info  		N.A.  LDD0021  [14]
Compound 10
 Probe Info  		N.A.  LDD2216  [15]
Compound 11
 Probe Info  		N.A.  LDD2213  [15]
NHS
 Probe Info  		K433(0.00); K117(0.00); K394(0.00)  LDD0010  [14]
PF-06672131
 Probe Info  		N.A.  LDD0017  [16]
SF
 Probe Info  		N.A.  LDD0028  [17]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [18]
1c-yne
 Probe Info  		N.A.  LDD0228  [19]
Acrolein
 Probe Info  		C936(0.00); H210(0.00); C1073(0.00); H140(0.00)  LDD0217  [20]
Cinnamaldehyde
 Probe Info  		N.A.  LDD0220  [20]
Crotonaldehyde
 Probe Info  		C936(0.00); H210(0.00); C308(0.00); C1073(0.00)  LDD0219  [20]
Methacrolein
 Probe Info  		C1073(0.00); C308(0.00); C936(0.00)  LDD0218  [20]
W1
 Probe Info  		N.A.  LDD0236  [21]
NAIA_5
 Probe Info  		N.A.  LDD2223  [22]
TPP-AC
 Probe Info  		N.A.  LDD0427  [23]
PAL-AfBPP Probe
Click To Hide/Show 123 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C004
 Probe Info  		7.41  LDD1714  [24]
C017
 Probe Info  		7.31  LDD1725  [24]
C022
 Probe Info  		25.28  LDD1728  [24]
C039
 Probe Info  		4.92  LDD1739  [24]
C040
 Probe Info  		9.51  LDD1740  [24]
C041
 Probe Info  		5.90  LDD1741  [24]
C051
 Probe Info  		15.45  LDD1749  [24]
C052
 Probe Info  		5.24  LDD1750  [24]
C053
 Probe Info  		9.51  LDD1751  [24]
C063
 Probe Info  		17.15  LDD1760  [24]
C070
 Probe Info  		18.51  LDD1766  [24]
C082
 Probe Info  		7.11  LDD1774  [24]
C087
 Probe Info  		17.63  LDD1779  [24]
C091
 Probe Info  		22.32  LDD1782  [24]
C092
 Probe Info  		20.82  LDD1783  [24]
C094
 Probe Info  		27.86  LDD1785  [24]
C095
 Probe Info  		7.31  LDD1786  [24]
C100
 Probe Info  		10.93  LDD1789  [24]
C106
 Probe Info  		42.22  LDD1793  [24]
C107
 Probe Info  		19.03  LDD1794  [24]
C110
 Probe Info  		10.13  LDD1797  [24]
C112
 Probe Info  		40.79  LDD1799  [24]
C130
 Probe Info  		6.63  LDD1812  [24]
C134
 Probe Info  		42.81  LDD1816  [24]
C135
 Probe Info  		10.34  LDD1817  [24]
C139
 Probe Info  		11.55  LDD1821  [24]
C140
 Probe Info  		11.63  LDD1822  [24]
C142
 Probe Info  		6.23  LDD1824  [24]
C143
 Probe Info  		29.65  LDD1825  [24]
C153
 Probe Info  		18.64  LDD1834  [24]
C159
 Probe Info  		13.64  LDD1839  [24]
C161
 Probe Info  		23.75  LDD1841  [24]
C163
 Probe Info  		12.38  LDD1843  [24]
C165
 Probe Info  		15.03  LDD1845  [24]
C169
 Probe Info  		46.53  LDD1849  [24]
C170
 Probe Info  		21.56  LDD1850  [24]
C177
 Probe Info  		11.55  LDD1856  [24]
C186
 Probe Info  		9.19  LDD1864  [24]
C187
 Probe Info  		71.01  LDD1865  [24]
C191
 Probe Info  		9.58  LDD1868  [24]
C193
 Probe Info  		4.96  LDD1869  [24]
C198
 Probe Info  		12.73  LDD1874  [24]
C199
 Probe Info  		5.90  LDD1875  [24]
C201
 Probe Info  		86.82  LDD1877  [24]
C206
 Probe Info  		27.28  LDD1881  [24]
C218
 Probe Info  		44.94  LDD1892  [24]
C219
 Probe Info  		7.46  LDD1893  [24]
C220
 Probe Info  		23.75  LDD1894  [24]
C225
 Probe Info  		8.57  LDD1898  [24]
C228
 Probe Info  		35.26  LDD1901  [24]
C231
 Probe Info  		16.56  LDD1904  [24]
C233
 Probe Info  		15.78  LDD1906  [24]
C235
 Probe Info  		17.51  LDD1908  [24]
C240
 Probe Info  		11.96  LDD1913  [24]
C246
 Probe Info  		27.86  LDD1919  [24]
C252
 Probe Info  		12.55  LDD1925  [24]
C258
 Probe Info  		9.06  LDD1931  [24]
C264
 Probe Info  		25.46  LDD1935  [24]
C271
 Probe Info  		7.41  LDD1941  [24]
C286
 Probe Info  		5.58  LDD1956  [24]
C287
 Probe Info  		9.65  LDD1957  [24]
C288
 Probe Info  		9.13  LDD1958  [24]
C289
 Probe Info  		27.67  LDD1959  [24]
C290
 Probe Info  		10.34  LDD1960  [24]
C293
 Probe Info  		20.53  LDD1963  [24]
C296
 Probe Info  		15.56  LDD1966  [24]
C297
 Probe Info  		5.66  LDD1967  [24]
C299
 Probe Info  		7.11  LDD1968  [24]
C305
 Probe Info  		13.18  LDD1974  [24]
C307
 Probe Info  		6.02  LDD1975  [24]
C310
 Probe Info  		13.27  LDD1977  [24]
C314
 Probe Info  		18.25  LDD1981  [24]
C317
 Probe Info  		13.93  LDD1983  [24]
C322
 Probe Info  		7.94  LDD1988  [24]
C326
 Probe Info  		11.63  LDD1990  [24]
C338
 Probe Info  		13.93  LDD2001  [24]
C339
 Probe Info  		10.70  LDD2002  [24]
C348
 Probe Info  		22.01  LDD2009  [24]
C349
 Probe Info  		16.45  LDD2010  [24]
C350
 Probe Info  		61.39  LDD2011  [24]
C353
 Probe Info  		5.98  LDD2014  [24]
C355
 Probe Info  		29.45  LDD2016  [24]
C356
 Probe Info  		25.81  LDD2017  [24]
C357
 Probe Info  		8.00  LDD2018  [24]
C360
 Probe Info  		7.01  LDD2021  [24]
C361
 Probe Info  		18.13  LDD2022  [24]
C362
 Probe Info  		38.05  LDD2023  [24]
C364
 Probe Info  		22.16  LDD2025  [24]
C366
 Probe Info  		8.22  LDD2027  [24]
C367
 Probe Info  		5.50  LDD2028  [24]
C376
 Probe Info  		8.94  LDD2036  [24]
C378
 Probe Info  		7.01  LDD2037  [24]
C380
 Probe Info  		12.82  LDD2039  [24]
C382
 Probe Info  		13.27  LDD2041  [24]
C388
 Probe Info  		36.50  LDD2047  [24]
C390
 Probe Info  		53.82  LDD2049  [24]
C391
 Probe Info  		23.10  LDD2050  [24]
C399
 Probe Info  		7.21  LDD2058  [24]
C403
 Probe Info  		19.16  LDD2061  [24]
C407
 Probe Info  		13.09  LDD2064  [24]
C413
 Probe Info  		23.10  LDD2069  [24]
C419
 Probe Info  		22.32  LDD2074  [24]
C420
 Probe Info  		15.03  LDD2075  [24]
C421
 Probe Info  		6.50  LDD2076  [24]
C424
 Probe Info  		13.18  LDD2079  [24]
C430
 Probe Info  		5.86  LDD2085  [24]
C433
 Probe Info  		7.84  LDD2088  [24]
FFF probe11
 Probe Info  		20.00  LDD0471  [25]
FFF probe13
 Probe Info  		20.00  LDD0475  [25]
FFF probe14
 Probe Info  		20.00  LDD0477  [25]
FFF probe15
 Probe Info  		12.18  LDD0478  [25]
FFF probe2
 Probe Info  		14.68  LDD0463  [25]
FFF probe3
 Probe Info  		20.00  LDD0464  [25]
FFF probe4
 Probe Info  		14.41  LDD0466  [25]
FFF probe6
 Probe Info  		20.00  LDD0467  [25]
FFF probe9
 Probe Info  		5.10  LDD0470  [25]
JN0003
 Probe Info  		20.00  LDD0469  [25]
STS-1
 Probe Info  		N.A.  LDD0136  [26]
STS-2
 Probe Info  		N.A.  LDD0138  [26]
VE-P
 Probe Info  		N.A.  LDD0396  [27]
Photocelecoxib
 Probe Info  		N.A.  LDD0019  [28]
OEA-DA
 Probe Info  		6.37  LDD0046  [29]
Probe 12
 Probe Info  		N.A.  LDD0420  [30]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C1073(0.80)  LDD2142  [6]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C1073(1.00)  LDD2112  [6]
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C1073(0.69)  LDD2095  [6]
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C1073(0.97)  LDD2130  [6]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C1073(0.74); C308(0.88)  LDD2117  [6]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C1073(1.32)  LDD2152  [6]
 LDCM0510  3-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)-3-oxopropanenitrile MDA-MB-231 C1073(1.07)  LDD2103  [6]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C1073(0.56)  LDD2132  [6]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C1073(0.90)  LDD2131  [6]
 LDCM0214  AC1 PaTu 8988t C1073(0.28); C936(0.63)  LDD1093  [31]
 LDCM0215  AC10 HEK-293T C1073(0.86)  LDD0813  [31]
 LDCM0216  AC100 HEK-293T C1073(1.00); C936(1.01)  LDD0814  [31]
 LDCM0217  AC101 HEK-293T C1073(1.00); C936(1.05)  LDD0815  [31]
 LDCM0218  AC102 HEK-293T C1073(0.94); C936(0.96)  LDD0816  [31]
 LDCM0219  AC103 HEK-293T C1073(1.03); C936(0.91)  LDD0817  [31]
 LDCM0220  AC104 HEK-293T C1073(0.81); C936(0.91)  LDD0818  [31]
 LDCM0221  AC105 HEK-293T C1073(1.30); C936(1.13)  LDD0819  [31]
 LDCM0222  AC106 HEK-293T C1073(1.38); C936(1.10)  LDD0820  [31]
 LDCM0223  AC107 HEK-293T C1073(0.93); C936(1.07)  LDD0821  [31]
 LDCM0224  AC108 HEK-293T C1073(1.29); C936(1.02)  LDD0822  [31]
 LDCM0225  AC109 HEK-293T C1073(1.00); C936(0.97)  LDD0823  [31]
 LDCM0226  AC11 HEK-293T C1073(1.08)  LDD0824  [31]
 LDCM0227  AC110 HEK-293T C1073(0.92); C936(1.14)  LDD0825  [31]
 LDCM0228  AC111 HEK-293T C1073(1.21); C936(1.05)  LDD0826  [31]
 LDCM0229  AC112 HEK-293T C1073(1.23); C936(1.09)  LDD0827  [31]
 LDCM0230  AC113 HEK-293T C936(1.19)  LDD0828  [31]
 LDCM0231  AC114 HEK-293T C936(0.94)  LDD0829  [31]
 LDCM0232  AC115 HEK-293T C936(1.15)  LDD0830  [31]
 LDCM0233  AC116 HEK-293T C936(0.96)  LDD0831  [31]
 LDCM0234  AC117 HEK-293T C936(1.13)  LDD0832  [31]
 LDCM0235  AC118 HEK-293T C936(1.21)  LDD0833  [31]
 LDCM0236  AC119 HEK-293T C936(1.15)  LDD0834  [31]
 LDCM0237  AC12 HEK-293T C1073(0.85)  LDD0835  [31]
 LDCM0238  AC120 HEK-293T C936(1.28)  LDD0836  [31]
 LDCM0239  AC121 HEK-293T C936(1.55)  LDD0837  [31]
 LDCM0240  AC122 HEK-293T C936(1.10)  LDD0838  [31]
 LDCM0241  AC123 HEK-293T C936(1.01)  LDD0839  [31]
 LDCM0242  AC124 HEK-293T C936(1.65)  LDD0840  [31]
 LDCM0243  AC125 HEK-293T C936(1.19)  LDD0841  [31]
 LDCM0244  AC126 HEK-293T C936(1.43)  LDD0842  [31]
 LDCM0245  AC127 HEK-293T C936(1.19)  LDD0843  [31]
 LDCM0246  AC128 HEK-293T C936(0.54)  LDD0844  [31]
 LDCM0247  AC129 HEK-293T C936(0.49)  LDD0845  [31]
 LDCM0249  AC130 HEK-293T C936(0.63)  LDD0847  [31]
 LDCM0250  AC131 HEK-293T C936(1.04)  LDD0848  [31]
 LDCM0251  AC132 HEK-293T C936(0.60)  LDD0849  [31]
 LDCM0252  AC133 HEK-293T C936(0.68)  LDD0850  [31]
 LDCM0253  AC134 HEK-293T C936(0.68)  LDD0851  [31]
 LDCM0254  AC135 HEK-293T C936(0.73)  LDD0852  [31]
 LDCM0255  AC136 HEK-293T C936(0.66)  LDD0853  [31]
 LDCM0256  AC137 HEK-293T C936(0.59)  LDD0854  [31]
 LDCM0257  AC138 HEK-293T C936(0.66)  LDD0855  [31]
 LDCM0258  AC139 HEK-293T C936(0.62)  LDD0856  [31]
 LDCM0259  AC14 HEK-293T C1073(1.08)  LDD0857  [31]
 LDCM0260  AC140 HEK-293T C936(0.62)  LDD0858  [31]
 LDCM0261  AC141 HEK-293T C936(0.70)  LDD0859  [31]
 LDCM0262  AC142 HEK-293T C936(0.52)  LDD0860  [31]
 LDCM0263  AC143 HEK-293T C936(1.01)  LDD0861  [31]
 LDCM0264  AC144 HEK-293T C936(1.07)  LDD0862  [31]
 LDCM0265  AC145 HEK-293T C936(0.86)  LDD0863  [31]
 LDCM0266  AC146 HEK-293T C936(1.00)  LDD0864  [31]
 LDCM0267  AC147 HEK-293T C936(1.60)  LDD0865  [31]
 LDCM0268  AC148 HEK-293T C936(1.16)  LDD0866  [31]
 LDCM0269  AC149 HEK-293T C936(1.02)  LDD0867  [31]
 LDCM0270  AC15 HEK-293T C1073(1.05)  LDD0868  [31]
 LDCM0271  AC150 HEK-293T C936(1.29)  LDD0869  [31]
 LDCM0272  AC151 HEK-293T C936(0.82)  LDD0870  [31]
 LDCM0273  AC152 HEK-293T C936(1.01)  LDD0871  [31]
 LDCM0274  AC153 HEK-293T C936(1.00)  LDD0872  [31]
 LDCM0621  AC154 HEK-293T C936(1.50)  LDD2162  [31]
 LDCM0622  AC155 HEK-293T C936(0.92)  LDD2163  [31]
 LDCM0623  AC156 HEK-293T C936(0.86)  LDD2164  [31]
 LDCM0624  AC157 HEK-293T C936(1.46)  LDD2165  [31]
 LDCM0276  AC17 HEK-293T C1073(0.66); C936(0.62)  LDD0874  [31]
 LDCM0277  AC18 HEK-293T C1073(0.71); C936(0.67)  LDD0875  [31]
 LDCM0278  AC19 HEK-293T C1073(0.88); C936(0.75)  LDD0876  [31]
 LDCM0279  AC2 PaTu 8988t C1073(0.39); C936(0.75)  LDD1158  [31]
 LDCM0280  AC20 HEK-293T C1073(1.13); C936(0.60)  LDD0878  [31]
 LDCM0281  AC21 HEK-293T C1073(0.88); C936(0.64)  LDD0879  [31]
 LDCM0282  AC22 HEK-293T C1073(1.02); C936(0.69)  LDD0880  [31]
 LDCM0283  AC23 HEK-293T C1073(0.61); C936(0.60)  LDD0881  [31]
 LDCM0284  AC24 HEK-293T C1073(0.73); C936(0.75)  LDD0882  [31]
 LDCM0285  AC25 HEK-293T C1073(1.01)  LDD0883  [31]
 LDCM0286  AC26 HEK-293T C1073(0.78)  LDD0884  [31]
 LDCM0287  AC27 HEK-293T C1073(0.73)  LDD0885  [31]
 LDCM0288  AC28 HEK-293T C1073(0.99)  LDD0886  [31]
 LDCM0289  AC29 HEK-293T C1073(1.06)  LDD0887  [31]
 LDCM0290  AC3 PaTu 8988t C1073(0.31); C936(0.77)  LDD1169  [31]
 LDCM0291  AC30 HEK-293T C1073(1.00)  LDD0889  [31]
 LDCM0292  AC31 HEK-293T C1073(1.02)  LDD0890  [31]
 LDCM0293  AC32 HEK-293T C1073(0.85)  LDD0891  [31]
 LDCM0294  AC33 HEK-293T C1073(0.76)  LDD0892  [31]
 LDCM0295  AC34 HEK-293T C1073(0.76)  LDD0893  [31]
 LDCM0296  AC35 HEK-293T C1073(0.73)  LDD0894  [31]
 LDCM0297  AC36 HEK-293T C1073(1.01)  LDD0895  [31]
 LDCM0298  AC37 HEK-293T C1073(0.68)  LDD0896  [31]
 LDCM0299  AC38 HEK-293T C1073(0.71)  LDD0897  [31]
 LDCM0300  AC39 HEK-293T C1073(0.69)  LDD0898  [31]
 LDCM0301  AC4 PaTu 8988t C1073(0.26); C936(0.86)  LDD1180  [31]
 LDCM0302  AC40 HEK-293T C1073(0.67)  LDD0900  [31]
 LDCM0303  AC41 HEK-293T C1073(0.80)  LDD0901  [31]
 LDCM0304  AC42 HEK-293T C1073(0.76)  LDD0902  [31]
 LDCM0305  AC43 HEK-293T C1073(0.78)  LDD0903  [31]
 LDCM0306  AC44 HEK-293T C1073(0.72)  LDD0904  [31]
 LDCM0307  AC45 HEK-293T C1073(0.63)  LDD0905  [31]
 LDCM0308  AC46 PaTu 8988t C936(0.75)  LDD1187  [31]
 LDCM0309  AC47 PaTu 8988t C936(0.83)  LDD1188  [31]
 LDCM0310  AC48 PaTu 8988t C936(0.71)  LDD1189  [31]
 LDCM0311  AC49 PaTu 8988t C936(0.52)  LDD1190  [31]
 LDCM0312  AC5 PaTu 8988t C1073(0.22); C936(0.66)  LDD1191  [31]
 LDCM0313  AC50 PaTu 8988t C936(0.48)  LDD1192  [31]
 LDCM0314  AC51 PaTu 8988t C936(0.15)  LDD1193  [31]
 LDCM0315  AC52 PaTu 8988t C936(0.69)  LDD1194  [31]
 LDCM0316  AC53 PaTu 8988t C936(0.50)  LDD1195  [31]
 LDCM0317  AC54 PaTu 8988t C936(0.48)  LDD1196  [31]
 LDCM0318  AC55 PaTu 8988t C936(0.48)  LDD1197  [31]
 LDCM0319  AC56 PaTu 8988t C936(0.40)  LDD1198  [31]
 LDCM0320  AC57 HEK-293T C936(1.29)  LDD0918  [31]
 LDCM0321  AC58 HEK-293T C936(1.03)  LDD0919  [31]
 LDCM0322  AC59 HEK-293T C936(1.60)  LDD0920  [31]
 LDCM0323  AC6 HEK-293T C1073(1.29)  LDD0921  [31]
 LDCM0324  AC60 HEK-293T C936(1.49)  LDD0922  [31]
 LDCM0325  AC61 HEK-293T C936(1.21)  LDD0923  [31]
 LDCM0326  AC62 HEK-293T C936(1.14)  LDD0924  [31]
 LDCM0327  AC63 HEK-293T C936(1.06)  LDD0925  [31]
 LDCM0328  AC64 HEK-293T C936(1.17)  LDD0926  [31]
 LDCM0329  AC65 HEK-293T C936(1.12)  LDD0927  [31]
 LDCM0330  AC66 HEK-293T C936(1.38)  LDD0928  [31]
 LDCM0331  AC67 HEK-293T C936(1.27)  LDD0929  [31]
 LDCM0332  AC68 HEK-293T C1073(1.23); C936(1.02)  LDD0930  [31]
 LDCM0333  AC69 HEK-293T C1073(1.00); C936(0.74)  LDD0931  [31]
 LDCM0334  AC7 HEK-293T C1073(1.08)  LDD0932  [31]
 LDCM0335  AC70 HEK-293T C1073(0.96); C936(1.20)  LDD0933  [31]
 LDCM0336  AC71 HEK-293T C1073(0.73); C936(1.06)  LDD0934  [31]
 LDCM0337  AC72 HEK-293T C1073(0.80); C936(0.84)  LDD0935  [31]
 LDCM0338  AC73 HEK-293T C1073(1.14); C936(0.89)  LDD0936  [31]
 LDCM0339  AC74 HEK-293T C1073(0.90); C936(1.31)  LDD0937  [31]
 LDCM0340  AC75 HEK-293T C1073(1.10); C936(1.36)  LDD0938  [31]
 LDCM0341  AC76 HEK-293T C1073(1.17); C936(1.01)  LDD0939  [31]
 LDCM0342  AC77 HEK-293T C1073(1.13); C936(1.05)  LDD0940  [31]
 LDCM0343  AC78 HEK-293T C1073(0.91); C936(0.87)  LDD0941  [31]
 LDCM0344  AC79 HEK-293T C1073(1.21); C936(0.98)  LDD0942  [31]
 LDCM0345  AC8 HEK-293T C1073(1.05)  LDD0943  [31]
 LDCM0346  AC80 HEK-293T C1073(1.20); C936(0.95)  LDD0944  [31]
 LDCM0347  AC81 HEK-293T C1073(1.11); C936(0.76)  LDD0945  [31]
 LDCM0348  AC82 HEK-293T C1073(1.43); C936(0.79)  LDD0946  [31]
 LDCM0349  AC83 HEK-293T C936(1.02)  LDD0947  [31]
 LDCM0350  AC84 HEK-293T C936(0.86)  LDD0948  [31]
 LDCM0351  AC85 HEK-293T C936(0.91)  LDD0949  [31]
 LDCM0352  AC86 HEK-293T C936(1.02)  LDD0950  [31]
 LDCM0353  AC87 HEK-293T C936(0.72)  LDD0951  [31]
 LDCM0354  AC88 HEK-293T C936(0.87)  LDD0952  [31]
 LDCM0355  AC89 HEK-293T C936(1.04)  LDD0953  [31]
 LDCM0357  AC90 HEK-293T C936(0.90)  LDD0955  [31]
 LDCM0358  AC91 HEK-293T C936(0.89)  LDD0956  [31]
 LDCM0359  AC92 HEK-293T C936(0.87)  LDD0957  [31]
 LDCM0360  AC93 HEK-293T C936(0.94)  LDD0958  [31]
 LDCM0361  AC94 HEK-293T C936(0.82)  LDD0959  [31]
 LDCM0362  AC95 HEK-293T C936(1.20)  LDD0960  [31]
 LDCM0363  AC96 HEK-293T C936(0.91)  LDD0961  [31]
 LDCM0364  AC97 HEK-293T C936(0.82)  LDD0962  [31]
 LDCM0365  AC98 HEK-293T C1073(1.01); C936(1.28)  LDD0963  [31]
 LDCM0366  AC99 HEK-293T C1073(0.94); C936(1.07)  LDD0964  [31]
 LDCM0545  Acetamide MDA-MB-231 C1073(0.44)  LDD2138  [6]
 LDCM0520  AKOS000195272 MDA-MB-231 C1073(0.82)  LDD2113  [6]
 LDCM0248  AKOS034007472 HEK-293T C1073(1.44)  LDD0846  [31]
 LDCM0356  AKOS034007680 HEK-293T C1073(0.83)  LDD0954  [31]
 LDCM0275  AKOS034007705 HEK-293T C1073(0.84)  LDD0873  [31]
 LDCM0498  BS-3668 MDA-MB-231 C1073(0.36)  LDD2091  [6]
 LDCM0108  Chloroacetamide HeLa C936(0.00); H210(0.00); C1073(0.00); H370(0.00)  LDD0222  [20]
 LDCM0367  CL1 HEK-293T C936(0.84)  LDD0965  [31]
 LDCM0368  CL10 HEK-293T C936(0.69)  LDD0966  [31]
 LDCM0369  CL100 PaTu 8988t C1073(0.25); C936(0.80)  LDD1248  [31]
 LDCM0370  CL101 HEK-293T C1073(0.91)  LDD0968  [31]
 LDCM0371  CL102 HEK-293T C1073(0.81)  LDD0969  [31]
 LDCM0372  CL103 HEK-293T C1073(0.89)  LDD0970  [31]
 LDCM0373  CL104 HEK-293T C1073(1.01)  LDD0971  [31]
 LDCM0374  CL105 HEK-293T C1073(0.96); C936(0.71)  LDD0972  [31]
 LDCM0375  CL106 HEK-293T C1073(0.81); C936(0.57)  LDD0973  [31]
 LDCM0376  CL107 HEK-293T C1073(1.02); C936(0.73)  LDD0974  [31]
 LDCM0377  CL108 HEK-293T C1073(1.00); C936(0.74)  LDD0975  [31]
 LDCM0378  CL109 HEK-293T C1073(0.90); C936(0.75)  LDD0976  [31]
 LDCM0379  CL11 HEK-293T C936(0.90)  LDD0977  [31]
 LDCM0380  CL110 HEK-293T C1073(0.97); C936(0.65)  LDD0978  [31]
 LDCM0381  CL111 HEK-293T C1073(0.87); C936(0.82)  LDD0979  [31]
 LDCM0382  CL112 HEK-293T C1073(1.14)  LDD0980  [31]
 LDCM0383  CL113 HEK-293T C1073(1.28)  LDD0981  [31]
 LDCM0384  CL114 HEK-293T C1073(1.13)  LDD0982  [31]
 LDCM0385  CL115 HEK-293T C1073(0.78)  LDD0983  [31]
 LDCM0386  CL116 HEK-293T C1073(0.82)  LDD0984  [31]
 LDCM0387  CL117 HEK-293T C1073(0.80)  LDD0985  [31]
 LDCM0388  CL118 HEK-293T C1073(0.57)  LDD0986  [31]
 LDCM0389  CL119 HEK-293T C1073(0.77)  LDD0987  [31]
 LDCM0390  CL12 HEK-293T C936(1.09)  LDD0988  [31]
 LDCM0391  CL120 HEK-293T C1073(0.66)  LDD0989  [31]
 LDCM0392  CL121 PaTu 8988t C936(0.81)  LDD1271  [31]
 LDCM0393  CL122 PaTu 8988t C936(0.70)  LDD1272  [31]
 LDCM0394  CL123 PaTu 8988t C936(0.59)  LDD1273  [31]
 LDCM0395  CL124 PaTu 8988t C936(0.61)  LDD1274  [31]
 LDCM0396  CL125 HEK-293T C936(1.11)  LDD0994  [31]
 LDCM0397  CL126 HEK-293T C936(1.26)  LDD0995  [31]
 LDCM0398  CL127 HEK-293T C936(0.92)  LDD0996  [31]
 LDCM0399  CL128 HEK-293T C936(1.01)  LDD0997  [31]
 LDCM0400  CL13 HEK-293T C936(1.05)  LDD0998  [31]
 LDCM0401  CL14 HEK-293T C936(0.90)  LDD0999  [31]
 LDCM0402  CL15 HEK-293T C936(0.73)  LDD1000  [31]
 LDCM0403  CL16 HEK-293T C1073(1.17); C936(1.16)  LDD1001  [31]
 LDCM0404  CL17 HEK-293T C1073(0.93); C936(0.95)  LDD1002  [31]
 LDCM0405  CL18 HEK-293T C1073(1.06); C936(0.96)  LDD1003  [31]
 LDCM0406  CL19 HEK-293T C1073(0.90); C936(1.05)  LDD1004  [31]
 LDCM0407  CL2 HEK-293T C936(1.08)  LDD1005  [31]
 LDCM0408  CL20 HEK-293T C1073(1.04); C936(0.88)  LDD1006  [31]
 LDCM0409  CL21 HEK-293T C1073(0.86); C936(0.77)  LDD1007  [31]
 LDCM0410  CL22 HEK-293T C1073(0.85); C936(0.87)  LDD1008  [31]
 LDCM0411  CL23 HEK-293T C1073(0.83); C936(1.28)  LDD1009  [31]
 LDCM0412  CL24 HEK-293T C1073(1.01); C936(0.89)  LDD1010  [31]
 LDCM0413  CL25 HEK-293T C1073(0.81); C936(0.97)  LDD1011  [31]
 LDCM0414  CL26 HEK-293T C1073(0.95); C936(1.06)  LDD1012  [31]
 LDCM0415  CL27 HEK-293T C1073(0.98); C936(1.29)  LDD1013  [31]
 LDCM0416  CL28 HEK-293T C1073(0.94); C936(1.49)  LDD1014  [31]
 LDCM0417  CL29 HEK-293T C1073(0.91); C936(0.92)  LDD1015  [31]
 LDCM0418  CL3 HEK-293T C936(0.88)  LDD1016  [31]
 LDCM0419  CL30 HEK-293T C1073(0.93); C936(1.03)  LDD1017  [31]
 LDCM0420  CL31 PaTu 8988t C1073(0.79); C936(0.96)  LDD1299  [31]
 LDCM0421  CL32 PaTu 8988t C1073(0.73); C936(0.78)  LDD1300  [31]
 LDCM0422  CL33 PaTu 8988t C1073(0.62); C936(0.66)  LDD1301  [31]
 LDCM0423  CL34 PaTu 8988t C1073(0.70); C936(0.69)  LDD1302  [31]
 LDCM0424  CL35 PaTu 8988t C1073(0.70); C936(0.69)  LDD1303  [31]
 LDCM0425  CL36 PaTu 8988t C1073(0.17); C936(0.40)  LDD1304  [31]
 LDCM0426  CL37 PaTu 8988t C1073(0.85); C936(0.65)  LDD1305  [31]
 LDCM0428  CL39 PaTu 8988t C1073(0.79); C936(0.65)  LDD1307  [31]
 LDCM0429  CL4 HEK-293T C936(0.88)  LDD1027  [31]
 LDCM0430  CL40 PaTu 8988t C1073(0.54); C936(0.81)  LDD1309  [31]
 LDCM0431  CL41 PaTu 8988t C1073(0.60); C936(0.64)  LDD1310  [31]
 LDCM0432  CL42 PaTu 8988t C1073(0.68); C936(0.70)  LDD1311  [31]
 LDCM0433  CL43 PaTu 8988t C1073(0.66); C936(0.60)  LDD1312  [31]
 LDCM0434  CL44 PaTu 8988t C1073(0.40); C936(0.56)  LDD1313  [31]
 LDCM0435  CL45 PaTu 8988t C1073(0.50); C936(0.70)  LDD1314  [31]
 LDCM0436  CL46 PaTu 8988t C1073(0.88); C936(0.89)  LDD1315  [31]
 LDCM0437  CL47 PaTu 8988t C1073(0.84); C936(0.87)  LDD1316  [31]
 LDCM0438  CL48 PaTu 8988t C1073(0.93); C936(0.82)  LDD1317  [31]
 LDCM0439  CL49 PaTu 8988t C1073(0.84); C936(0.95)  LDD1318  [31]
 LDCM0440  CL5 HEK-293T C936(0.86)  LDD1038  [31]
 LDCM0441  CL50 PaTu 8988t C1073(0.71); C936(0.80)  LDD1320  [31]
 LDCM0442  CL51 PaTu 8988t C1073(0.97); C936(0.89)  LDD1321  [31]
 LDCM0443  CL52 PaTu 8988t C1073(0.76); C936(0.92)  LDD1322  [31]
 LDCM0444  CL53 PaTu 8988t C1073(0.59); C936(0.73)  LDD1323  [31]
 LDCM0445  CL54 PaTu 8988t C1073(0.77); C936(0.82)  LDD1324  [31]
 LDCM0446  CL55 PaTu 8988t C1073(0.69); C936(0.76)  LDD1325  [31]
 LDCM0447  CL56 PaTu 8988t C1073(0.45); C936(0.78)  LDD1326  [31]
 LDCM0448  CL57 PaTu 8988t C1073(0.51); C936(0.86)  LDD1327  [31]
 LDCM0449  CL58 PaTu 8988t C1073(0.61); C936(0.81)  LDD1328  [31]
 LDCM0450  CL59 PaTu 8988t C1073(0.53); C936(0.89)  LDD1329  [31]
 LDCM0451  CL6 HEK-293T C936(0.91)  LDD1049  [31]
 LDCM0452  CL60 PaTu 8988t C1073(0.59); C936(1.01)  LDD1331  [31]
 LDCM0453  CL61 HEK-293T C936(0.90)  LDD1051  [31]
 LDCM0454  CL62 HEK-293T C936(0.88)  LDD1052  [31]
 LDCM0455  CL63 HEK-293T C936(1.35)  LDD1053  [31]
 LDCM0456  CL64 HEK-293T C936(0.92)  LDD1054  [31]
 LDCM0457  CL65 HEK-293T C936(0.89)  LDD1055  [31]
 LDCM0458  CL66 HEK-293T C936(1.04)  LDD1056  [31]
 LDCM0459  CL67 HEK-293T C936(0.79)  LDD1057  [31]
 LDCM0460  CL68 HEK-293T C936(0.88)  LDD1058  [31]
 LDCM0461  CL69 HEK-293T C936(1.00)  LDD1059  [31]
 LDCM0462  CL7 HEK-293T C936(0.94)  LDD1060  [31]
 LDCM0463  CL70 HEK-293T C936(1.07)  LDD1061  [31]
 LDCM0464  CL71 HEK-293T C936(1.05)  LDD1062  [31]
 LDCM0465  CL72 HEK-293T C936(0.94)  LDD1063  [31]
 LDCM0466  CL73 HEK-293T C936(0.75)  LDD1064  [31]
 LDCM0467  CL74 HEK-293T C936(1.08)  LDD1065  [31]
 LDCM0469  CL76 HEK-293T C936(1.62)  LDD1067  [31]
 LDCM0470  CL77 HEK-293T C936(0.79)  LDD1068  [31]
 LDCM0471  CL78 HEK-293T C936(0.92)  LDD1069  [31]
 LDCM0472  CL79 HEK-293T C936(0.81)  LDD1070  [31]
 LDCM0473  CL8 PaTu 8988t C1073(0.54); C936(0.63)  LDD1352  [31]
 LDCM0474  CL80 HEK-293T C936(1.06)  LDD1072  [31]
 LDCM0475  CL81 HEK-293T C936(0.85)  LDD1073  [31]
 LDCM0476  CL82 HEK-293T C936(0.82)  LDD1074  [31]
 LDCM0477  CL83 HEK-293T C936(1.21)  LDD1075  [31]
 LDCM0478  CL84 HEK-293T C936(0.94)  LDD1076  [31]
 LDCM0479  CL85 HEK-293T C936(0.76)  LDD1077  [31]
 LDCM0480  CL86 HEK-293T C936(0.64)  LDD1078  [31]
 LDCM0481  CL87 HEK-293T C936(0.64)  LDD1079  [31]
 LDCM0482  CL88 HEK-293T C936(0.75)  LDD1080  [31]
 LDCM0483  CL89 HEK-293T C936(1.01)  LDD1081  [31]
 LDCM0484  CL9 PaTu 8988t C1073(0.57); C936(0.77)  LDD1363  [31]
 LDCM0485  CL90 HEK-293T C936(0.84)  LDD1083  [31]
 LDCM0486  CL91 PaTu 8988t C1073(0.41); C936(0.90)  LDD1365  [31]
 LDCM0487  CL92 PaTu 8988t C1073(0.40); C936(0.76)  LDD1366  [31]
 LDCM0488  CL93 PaTu 8988t C1073(0.31); C936(0.81)  LDD1367  [31]
 LDCM0489  CL94 PaTu 8988t C1073(0.40); C936(0.76)  LDD1368  [31]
 LDCM0490  CL95 PaTu 8988t C1073(0.29); C936(0.57)  LDD1369  [31]
 LDCM0491  CL96 PaTu 8988t C1073(0.35); C936(0.70)  LDD1370  [31]
 LDCM0492  CL97 PaTu 8988t C1073(0.32); C936(0.84)  LDD1371  [31]
 LDCM0493  CL98 PaTu 8988t C1073(0.21); C936(0.51)  LDD1372  [31]
 LDCM0494  CL99 PaTu 8988t C1073(0.35); C936(0.74)  LDD1373  [31]
 LDCM0189  Compound 16 HEK-293T 20.66  LDD0492  [25]
 LDCM0182  Compound 18 HEK-293T 4.22  LDD0501  [25]
 LDCM0191  Compound 21 HEK-293T 5.81  LDD0493  [25]
 LDCM0190  Compound 34 HEK-293T 6.65  LDD0497  [25]
 LDCM0192  Compound 35 HEK-293T 5.69  LDD0491  [25]
 LDCM0193  Compound 36 HEK-293T 4.67  LDD0494  [25]
 LDCM0194  Compound 37 HEK-293T 16.70  LDD0498  [25]
 LDCM0195  Compound 38 HEK-293T 12.66  LDD0499  [25]
 LDCM0196  Compound 39 HEK-293T 5.10  LDD0496  [25]
 LDCM0197  Compound 40 HEK-293T 5.23  LDD0495  [25]
 LDCM0181  Compound 41 HEK-293T 4.53  LDD0502  [25]
 LDCM0165  Compound 9 HL-60 N.A.  LDD0420  [30]
 LDCM0495  E2913 HEK-293T C308(0.98); C936(1.03)  LDD1698  [32]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C1073(2.81)  LDD1702  [6]
 LDCM0625  F8 Ramos C1073(1.06); C936(0.60)  LDD2187  [33]
 LDCM0572  Fragment10 Ramos C1073(0.88); C936(0.55)  LDD2189  [33]
 LDCM0573  Fragment11 Ramos C1073(10.07); C936(2.41)  LDD2190  [33]
 LDCM0574  Fragment12 Ramos C1073(0.89); C936(0.67)  LDD2191  [33]
 LDCM0575  Fragment13 Ramos C936(0.90)  LDD2192  [33]
 LDCM0576  Fragment14 Ramos C1073(0.34); C936(0.51)  LDD2193  [33]
 LDCM0579  Fragment20 Ramos C1073(0.37); C936(0.82)  LDD2194  [33]
 LDCM0580  Fragment21 Ramos C1073(0.95); C936(0.90)  LDD2195  [33]
 LDCM0582  Fragment23 Ramos C936(0.74)  LDD2196  [33]
 LDCM0578  Fragment27 Ramos C936(0.97)  LDD2197  [33]
 LDCM0588  Fragment30 Ramos C1073(1.23); C936(0.96)  LDD2199  [33]
 LDCM0589  Fragment31 Ramos C1073(0.43); C936(0.37)  LDD2200  [33]
 LDCM0590  Fragment32 Ramos C1073(1.19); C936(0.57)  LDD2201  [33]
 LDCM0468  Fragment33 HEK-293T C936(1.00)  LDD1066  [31]
 LDCM0596  Fragment38 Ramos C1073(1.41); C936(0.72)  LDD2203  [33]
 LDCM0566  Fragment4 Ramos C936(0.88)  LDD2184  [33]
 LDCM0427  Fragment51 PaTu 8988t C1073(0.51); C936(0.53)  LDD1306  [31]
 LDCM0610  Fragment52 Ramos C1073(1.63); C936(0.98)  LDD2204  [33]
 LDCM0614  Fragment56 Ramos C1073(1.34); C936(0.97)  LDD2205  [33]
 LDCM0569  Fragment7 Ramos C936(0.56)  LDD2186  [33]
 LDCM0571  Fragment9 Ramos C1073(0.86); C936(0.57)  LDD2188  [33]
 LDCM0107  IAA HeLa H140(0.00); H370(0.00); C936(0.00); H210(0.00)  LDD0221  [20]
 LDCM0022  KB02 HEK-293T C308(0.99); C936(0.96)  LDD1492  [32]
 LDCM0023  KB03 Jurkat C308(16.54)  LDD0209  [8]
 LDCM0024  KB05 HMCB C936(2.34)  LDD3312  [34]
 LDCM0509  N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide MDA-MB-231 C1073(1.01)  LDD2102  [6]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C1073(0.60)  LDD2121  [6]
 LDCM0109  NEM HeLa H370(0.00); H210(0.00); H140(0.00)  LDD0223  [20]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C1073(0.69)  LDD2089  [6]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C1073(1.64)  LDD2090  [6]
 LDCM0499  Nucleophilic fragment 12b MDA-MB-231 C1073(0.87)  LDD2092  [6]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C1073(0.95); C308(1.02)  LDD2093  [6]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C1073(1.25)  LDD2094  [6]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C1073(0.12)  LDD2096  [6]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C1073(1.00)  LDD2097  [6]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C1073(0.96)  LDD2098  [6]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C1073(0.73); C308(1.02)  LDD2099  [6]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C1073(0.95); C308(0.86)  LDD2104  [6]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C1073(1.95)  LDD2105  [6]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C1073(0.79); C308(0.96); C936(0.60)  LDD2107  [6]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C1073(0.70)  LDD2108  [6]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C1073(1.03); C308(1.10); C936(0.91)  LDD2109  [6]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C1073(1.00); C308(1.01)  LDD2111  [6]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C1073(0.66)  LDD2114  [6]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C1073(0.46)  LDD2115  [6]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C1073(0.20)  LDD2118  [6]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C1073(3.34); C308(2.04)  LDD2119  [6]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C1073(0.90)  LDD2120  [6]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C1073(0.20)  LDD2122  [6]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C1073(1.01); C308(0.99)  LDD2123  [6]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C1073(0.19)  LDD2124  [6]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C1073(0.66); C308(0.78)  LDD2125  [6]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C1073(0.19)  LDD2126  [6]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C1073(0.83); C308(0.93)  LDD2127  [6]
 LDCM0535  Nucleophilic fragment 30b MDA-MB-231 C1073(0.62)  LDD2128  [6]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C1073(0.87)  LDD2129  [6]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C1073(0.92); C308(1.34); C936(0.87)  LDD2135  [6]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C1073(1.32); C308(1.10); C936(1.13)  LDD2136  [6]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C1073(0.98); C308(0.80)  LDD2137  [6]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C308(2.38); C1073(1.74)  LDD1700  [6]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C1073(0.60); C308(0.76)  LDD2140  [6]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C1073(0.69)  LDD2141  [6]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C308(1.14)  LDD2143  [6]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C1073(3.13); C308(2.50)  LDD2144  [6]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C1073(0.78); C308(0.98)  LDD2146  [6]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C1073(0.61); C308(0.61)  LDD2148  [6]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C1073(0.21)  LDD2149  [6]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C1073(0.54)  LDD2150  [6]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C308(0.38)  LDD2151  [6]
 LDCM0131  RA190 MM1.R C936(1.13)  LDD0304  [35]

The Interaction Atlas With This Target

The Drug(s) Related To This Target

Approved
Click To Hide/Show 3 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Nadh Small molecular drug DB00157
Sodium Oxybate . DB09072
Xanthinol . DB09092
Investigative
Click To Hide/Show 2 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
7-thionicotinamide-adenine-dinucleotide Phosphate . DB01763
Nicotinamide Adenine Dinucleotide Phosphate . DB03461

References

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Mass spectrometry data entry: PXD028270
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Mass spectrometry data entry: PXD039908 , PXD029761
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Mass spectrometry data entry: PXD042377
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Mass spectrometry data entry: PXD028853
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Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
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Mass spectrometry data entry: PXD029255
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Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD022279
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Mass spectrometry data entry: PXD036569
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Mass spectrometry data entry: PXD039931
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Mass spectrometry data entry: PXD033004
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Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD041587
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Mass spectrometry data entry: PXD007094
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Mass spectrometry data entry: PXD007570
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