Details of the Probe

General Information of Probe

Probe ID
LDPC0343
Probe Name
C092
Synonyms
Z4282859713
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 371.4
Lipid-water partition coefficient (xlogp) 3.7
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C22H21N5O
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[1-(naphthalen-1-ylmethyl)pyrazol-3-yl]propanamide
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)NC2=NN(C=C2)CC3=CC=CC4=CC=CC=C43
InChI
InChI=1S/C22H21N5O/c1-2-3-13-22(25-26-22)14-11-21(28)23-20-12-15-27(24-20)16-18-9-6-8-17-7-4-5-10-19(17)18/h1,4-10,12,15H,3,11,13-14,16H2,(H,23,24,28)
InChIKey
VSUGYYFEEDPTAM-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

166 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) LDTP06657 17.15  LDD1783 
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) LDTP02000 22.63  LDD1783 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 30.06  LDD1783 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 19.84  LDD1783 
Acid ceramidase (ASAH1) LDTP05905 36.00  LDD1783 
Acyl-CoA dehydrogenase family member 11 (ACAD11) LDTP07873 18.13  LDD1783 
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) LDTP09814 17.88  LDD1783 
ADP-dependent glucokinase (ADPGK) LDTP11127 83.29  LDD1783 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 23.26  LDD1783 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 53.45  LDD1783 
Antigen peptide transporter 2 (TAP2) LDTP05409 18.38  LDD1783 
Atlastin-2 (ATL2) LDTP09251 32.90  LDD1783 
ATP synthase membrane subunit K, mitochondrial (ATP5MK) LDTP10432 20.39  LDD1783 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 19.97  LDD1783 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 18.00  LDD1783 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 16.45  LDD1783 
ATPase GET3 (GET3) LDTP00836 18.25  LDD1783 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 20.39  LDD1783 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 56.49  LDD1783 
Calcium-transporting ATPase type 2C member 1 (ATP2C1) LDTP05228 19.16  LDD1783 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 43.41  LDD1783 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 18.00  LDD1783 
Catechol O-methyltransferase (COMT) LDTP03145 37.27  LDD1783 
Catechol O-methyltransferase domain-containing protein 1 (COMTD1) LDTP17587 18.64  LDD1783 
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) LDTP00416 19.70  LDD1783 
Ceramide glucosyltransferase (UGCG) LDTP06617 17.39  LDD1783 
Ceramide synthase 1 (CERS1) LDTP03394 23.10  LDD1783 
Ceramide synthase 2 (CERS2) LDTP10329 55.33  LDD1783 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 25.81  LDD1783 
Choline/ethanolaminephosphotransferase 1 (CEPT1) LDTP14264 30.70  LDD1783 
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (ST3GAL4) LDTP05638 31.12  LDD1783 
COP9 signalosome complex subunit 3 (COPS3) LDTP13675 22.01  LDD1783 
COP9 signalosome complex subunit 6 (COPS6) LDTP07966 18.64  LDD1783 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 81.01  LDD1783 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 22.78  LDD1783 
Cytochrome b5 type B (CYB5B) LDTP00697 99.73  LDD1783 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 28.84  LDD1783 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 45.57  LDD1783 
Cytosolic purine 5'-nucleotidase (NT5C2) LDTP04327 22.47  LDD1783 
Dehydrogenase/reductase SDR family member 7 (DHRS7) LDTP13959 17.88  LDD1783 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 30.27  LDD1783 
Delta(24)-sterol reductase (DHCR24) LDTP06375 21.56  LDD1783 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 24.42  LDD1783 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 71.51  LDD1783 
Dihydroxyacetone phosphate acyltransferase (GNPAT) LDTP00577 21.11  LDD1783 
DNA replication ATP-dependent helicase/nuclease DNA2 (DNA2) LDTP04420 17.15  LDD1783 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 21.56  LDD1783 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 56.10  LDD1783 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (STT3B) LDTP09388 19.16  LDD1783 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 55.33  LDD1783 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 25.11  LDD1783 
E3 ubiquitin-protein ligase TRIM13 (TRIM13) LDTP01065 83.29  LDD1783 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 19.16  LDD1783 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 28.64  LDD1783 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 24.08  LDD1783 
Epimerase family protein SDR39U1 (SDR39U1) LDTP16070 26.72  LDD1783 
Epoxide hydrolase 1 (EPHX1) LDTP02175 17.88  LDD1783 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 16.80  LDD1783 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 93.05  LDD1783 
Glycerol-3-phosphate acyltransferase 4 (GPAT4) LDTP08232 17.27  LDD1783 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 36.25  LDD1783 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 30.06  LDD1783 
GTP-binding protein SAR1a (SAR1A) LDTP12470 23.59  LDD1783 
Heme A synthase COX15 (COX15) LDTP07931 32.45  LDD1783 
Heme oxygenase 1 (HMOX1) LDTP02359 57.68  LDD1783 
Heme oxygenase 2 (HMOX2) LDTP03540 56.89  LDD1783 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 29.86  LDD1783 
Hexokinase-2 (HK2) LDTP04531 24.93  LDD1783 
Holocytochrome c-type synthase (HCCS) LDTP04581 38.32  LDD1783 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 19.16  LDD1783 
Inactive C-alpha-formylglycine-generating enzyme 2 (SUMF2) LDTP09056 23.75  LDD1783 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 26.91  LDD1783 
Inositol 1,4,5-trisphosphate receptor-interacting protein (ITPRIP) LDTP08532 26.17  LDD1783 
Isochorismatase domain-containing protein 1 (ISOC1) LDTP19851 17.63  LDD1783 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 19.56  LDD1783 
Lathosterol oxidase (SC5D) LDTP01329 25.99  LDD1783 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 16.68  LDD1783 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 22.47  LDD1783 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 61.39  LDD1783 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 25.28  LDD1783 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 31.12  LDD1783 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 30.27  LDD1783 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 38.85  LDD1783 
Lysosomal protective protein (CTSA) LDTP02505 23.43  LDD1783 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 60.13  LDD1783 
Microsomal glutathione S-transferase 2 (MGST2) LDTP10966 23.75  LDD1783 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 18.77  LDD1783 
Mitochondrial ribosome-associated GTPase 1 (MTG1) LDTP11177 32.00  LDD1783 
Mitochondrial ubiquitin ligase activator of NFKB 1 (MUL1) LDTP10038 42.81  LDD1783 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 37.79  LDD1783 
Mitofusin-1 (MFN1) LDTP08530 17.03  LDD1783 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 20.82  LDD1783 
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) LDTP08598 18.00  LDD1783 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 67.18  LDD1783 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 27.86  LDD1783 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 99.73  LDD1783 
NADH dehydrogenase 1 beta subcomplex subunit 11, mitochondrial (NDUFB11) LDTP12752 17.03  LDD1783 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 70.52  LDD1783 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 31.34  LDD1783 
NADH dehydrogenase 1 subunit C2 (NDUFC2) LDTP01560 32.45  LDD1783 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 67.65  LDD1783 
NADH-ubiquinone oxidoreductase chain 5 (MT-ND5) LDTP01986 25.28  LDD1783 
NADPH--cytochrome P450 reductase (POR) LDTP02848 17.03  LDD1783 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 21.86  LDD1783 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 60.97  LDD1783 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 25.99  LDD1783 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 37.01  LDD1783 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 21.26  LDD1783 
Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) LDTP00589 18.38  LDD1783 
Phosphatidate cytidylyltransferase 2 (CDS2) LDTP01649 49.52  LDD1783 
Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) LDTP12608 16.45  LDD1783 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 42.22  LDD1783 
Phosphatidylserine synthase 2 (PTDSS2) LDTP11284 27.10  LDD1783 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 22.47  LDD1783 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 16.45  LDD1783 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 57.28  LDD1783 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 33.13  LDD1783 
Presenilin-associated rhomboid-like protein, mitochondrial (PARL) LDTP11852 26.91  LDD1783 
Probable glutathione peroxidase 8 (GPX8) LDTP09495 17.15  LDD1783 
Prolyl 3-hydroxylase 1 (P3H1) LDTP06750 24.42  LDD1783 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 21.11  LDD1783 
Prostaglandin reductase 3 (PTGR3) LDTP15422 25.11  LDD1783 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 21.41  LDD1783 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 19.43  LDD1783 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 37.79  LDD1783 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 29.04  LDD1783 
Protein O-mannose kinase (POMK) LDTP11957 49.18  LDD1783 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 16.80  LDD1783 
Protein-L-histidine N-pros-methyltransferase (METTL9) LDTP15962 35.02  LDD1783 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 42.52  LDD1783 
Ras-related protein Rab-10 (RAB10) LDTP04895 17.75  LDD1783 
Ras-related protein Rab-1A (RAB1A) LDTP05006 18.51  LDD1783 
Ras-related protein Rab-24 (RAB24) LDTP10020 33.82  LDD1783 
Ras-related protein Rab-7L1 (RAB29) LDTP00492 19.03  LDD1783 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 83.29  LDD1783 
Retinol dehydrogenase 13 (RDH13) LDTP09061 29.04  LDD1783 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 19.43  LDD1783 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 39.95  LDD1783 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 40.22  LDD1783 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 99.73  LDD1783 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 34.06  LDD1783 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 19.97  LDD1783 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 29.86  LDD1783 
Squalene monooxygenase (SQLE) LDTP06142 43.11  LDD1783 
Squalene synthase (FDFT1) LDTP03842 24.93  LDD1783 
Stearoyl-CoA desaturase (SCD) LDTP00344 32.90  LDD1783 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 39.40  LDD1783 
Sulfide:quinone oxidoreductase, mitochondrial (SQOR) LDTP14278 21.86  LDD1783 
Thiol S-methyltransferase TMT1B (TMT1B) LDTP15155 17.88  LDD1783 
Thioredoxin-like protein 1 (TXNL1) LDTP00758 54.95  LDD1783 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 22.78  LDD1783 
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) LDTP07227 29.86  LDD1783 
Torsin-1B (TOR1B) LDTP00400 23.92  LDD1783 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 20.82  LDD1783 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 39.67  LDD1783 
Ubiquitin-associated domain-containing protein 2 (UBAC2) LDTP09060 21.86  LDD1783 
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) LDTP11867 33.59  LDD1783 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 21.71  LDD1783 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) LDTP07756 18.25  LDD1783 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 27.86  LDD1783 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 27.47  LDD1783 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 49.87  LDD1783 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 33.82  LDD1783 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 59.71  LDD1783 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 25.99  LDD1783 
Xaa-Pro aminopeptidase 3 (XPNPEP3) LDTP12420 17.75  LDD1783 
------------------------------------------------------------------------------------
⏷ Show the Full List of 166 Enzyme
125 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acyl-CoA-binding domain-containing protein 5 (ACBD5) LDTP07152 19.29  LDD1783 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 23.43  LDD1783 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 19.56  LDD1783 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 16.45  LDD1783 
Anoctamin-6 (ANO6) LDTP06855 20.68  LDD1783 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 19.43  LDD1783 
ATP synthase subunit a (MT-ATP6) LDTP01804 39.67  LDD1783 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 18.51  LDD1783 
ATP synthase subunit f, mitochondrial (ATP5MF) LDTP04723 17.51  LDD1783 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 44.32  LDD1783 
ATP synthase subunit gamma, mitochondrial (ATP5F1C) LDTP03810 36.50  LDD1783 
Autophagy-related protein 9A (ATG9A) LDTP08030 17.75  LDD1783 
B-cell receptor-associated protein 31 (BCAP31) LDTP04426 19.84  LDD1783 
Bax inhibitor 1 (TMBIM6) LDTP04663 23.43  LDD1783 
BOS complex subunit NCLN (NCLN) LDTP10036 16.56  LDD1783 
Ceroid-lipofuscinosis neuronal protein 6 (CLN6) LDTP12738 22.47  LDD1783 
Chloride channel CLIC-like protein 1 (CLCC1) LDTP10804 25.63  LDD1783 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 54.95  LDD1783 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 42.81  LDD1783 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 21.41  LDD1783 
Derlin-2 (DERL2) LDTP11634 18.51  LDD1783 
Endophilin-B1 (SH3GLB1) LDTP13953 28.84  LDD1783 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 31.78  LDD1783 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 99.73  LDD1783 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 58.89  LDD1783 
Etoposide-induced protein 2.4 homolog (EI24) LDTP00405 17.39  LDD1783 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 22.94  LDD1783 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 27.28  LDD1783 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 26.72  LDD1783 
Integral membrane protein 2B (ITM2B) LDTP13833 22.47  LDD1783 
Integral membrane protein 2C (ITM2C) LDTP12451 20.25  LDD1783 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 20.53  LDD1783 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 19.16  LDD1783 
Lysosome membrane protein 2 (SCARB2) LDTP06034 27.47  LDD1783 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 19.16  LDD1783 
Magnesium transporter protein 1 (MAGT1) LDTP11732 17.63  LDD1783 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 28.44  LDD1783 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 25.99  LDD1783 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 35.02  LDD1783 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 38.05  LDD1783 
Metal cation symporter ZIP14 (SLC39A14) LDTP06293 18.13  LDD1783 
Metaxin-1 (MTX1) LDTP05900 40.79  LDD1783 
MICOS complex subunit MIC26 (APOO) LDTP11250 60.97  LDD1783 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 18.90  LDD1783 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 17.88  LDD1783 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 40.79  LDD1783 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 34.30  LDD1783 
Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42) LDTP08279 53.08  LDD1783 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 45.25  LDD1783 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 27.86  LDD1783 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 40.79  LDD1783 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD1783 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 39.40  LDD1783 
Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) LDTP00821 17.27  LDD1783 
Mitochondrial import receptor subunit TOM40 homolog (TOMM40) LDTP01748 17.63  LDD1783 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 40.79  LDD1783 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 27.28  LDD1783 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 30.70  LDD1783 
Mpv17-like protein 2 (MPV17L2) LDTP14952 70.52  LDD1783 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 19.56  LDD1783 
Nucleoporin NDC1 (NDC1) LDTP11213 19.29  LDD1783 
Nucleoporin NUP35 (NUP35) LDTP09204 16.45  LDD1783 
Nucleoporin p54 (NUP54) LDTP08029 68.12  LDD1783 
Pannexin-1 (PANX1) LDTP10754 19.84  LDD1783 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 28.64  LDD1783 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 29.65  LDD1783 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 19.56  LDD1783 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 17.75  LDD1783 
Peroxisomal membrane protein PMP34 (SLC25A17) LDTP00872 17.75  LDD1783 
Phosphatidylinositol transfer protein alpha isoform (PITPNA) LDTP05236 16.56  LDD1783 
PRA1 family protein 2 (PRAF2) LDTP01060 16.68  LDD1783 
Programmed cell death protein 6 (PDCD6) LDTP01180 19.43  LDD1783 
Prosaposin (PSAP) LDTP02215 36.76  LDD1783 
Protein ERGIC-53 (LMAN1) LDTP04237 17.03  LDD1783 
Protein GPR107 (GPR107) LDTP07236 44.02  LDD1783 
Protein GPR108 (GPR108) LDTP12383 23.75  LDD1783 
Protein Mpv17 (MPV17) LDTP03869 29.24  LDD1783 
Protein RER1 (RER1) LDTP00590 24.93  LDD1783 
Protein RFT1 homolog (RFT1) LDTP10073 29.86  LDD1783 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 23.43  LDD1783 
Protein spinster homolog 1 (SPNS1) LDTP11844 40.22  LDD1783 
Protein tweety homolog 3 (TTYH3) LDTP11615 40.22  LDD1783 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 40.22  LDD1783 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 68.59  LDD1783 
Reduced folate transporter (SLC19A1) LDTP03952 20.39  LDD1783 
Reticulon-1 (RTN1) LDTP06633 25.81  LDD1783 
Rhomboid domain-containing protein 2 (RHBDD2) LDTP07467 34.54  LDD1783 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 22.47  LDD1783 
Secretory carrier-associated membrane protein 3 (SCAMP3) LDTP00451 25.11  LDD1783 
Sideroflexin-2 (SFXN2) LDTP10621 16.68  LDD1783 
Sideroflexin-4 (SFXN4) LDTP07531 27.86  LDD1783 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 32.90  LDD1783 
Sodium bicarbonate cotransporter 3 (SLC4A7) LDTP14275 17.27  LDD1783 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 24.42  LDD1783 
Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) LDTP11826 18.77  LDD1783 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 50.56  LDD1783 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 18.64  LDD1783 
Sorting nexin-19 (SNX19) LDTP09788 43.41  LDD1783 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 17.27  LDD1783 
Store-operated calcium entry-associated regulatory factor (SARAF) LDTP10148 23.59  LDD1783 
SUN domain-containing protein 1 (SUN1) LDTP01454 24.42  LDD1783 
Surfeit locus protein 4 (SURF4) LDTP00592 17.03  LDD1783 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 41.93  LDD1783 
Tetraspanin-10 (TSPAN10) LDTP15967 25.11  LDD1783 
Tetraspanin-3 (TSPAN3) LDTP16813 91.14  LDD1783 
Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 22.94  LDD1783 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 44.94  LDD1783 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 99.73  LDD1783 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 27.67  LDD1783 
Transmembrane 9 superfamily member 4 (TM9SF4) LDTP09789 22.16  LDD1783 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 18.90  LDD1783 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 20.97  LDD1783 
Transmembrane emp24 domain-containing protein 9 (TMED9) LDTP11291 21.26  LDD1783 
Transmembrane protein 126A (TMEM126A) LDTP15948 46.21  LDD1783 
Transmembrane protein 14C (TMEM14C) LDTP12979 22.16  LDD1783 
Transmembrane protein 199 (TMEM199) LDTP08881 60.13  LDD1783 
Transmembrane protein 201 (TMEM201) LDTP07058 19.97  LDD1783 
Transmembrane protein 205 (TMEM205) LDTP07667 22.78  LDD1783 
Transmembrane protein 230 (TMEM230) LDTP10065 50.91  LDD1783 
Transmembrane protein 33 (TMEM33) LDTP04787 17.75  LDD1783 
Transmembrane protein 59 (TMEM59) LDTP11406 32.22  LDD1783 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 39.95  LDD1783 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 54.57  LDD1783 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 77.71  LDD1783 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 55.33  LDD1783 
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⏷ Show the Full List of 125 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 25.63  LDD1783 
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2 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 18.38  LDD1783 
Leukocyte surface antigen CD47 (CD47) LDTP05572 21.11  LDD1783 
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108 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
60S ribosome subunit biogenesis protein NIP7 homolog (NIP7) LDTP13779 17.15  LDD1783 
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 20.39  LDD1783 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 18.51  LDD1783 
Armadillo repeat-containing protein 10 (ARMC10) LDTP08793 26.54  LDD1783 
ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) LDTP14716 25.46  LDD1783 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 26.17  LDD1783 
C-type mannose receptor 2 (MRC2) LDTP13114 17.27  LDD1783 
CCR4-NOT transcription complex subunit 9 (CNOT9) LDTP09813 21.71  LDD1783 
Clustered mitochondria protein homolog (CLUH) LDTP14486 25.63  LDD1783 
COMM domain-containing protein 7 (COMMD7) LDTP15294 37.79  LDD1783 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 99.73  LDD1783 
DnaJ homolog subfamily C member 11 (DNAJC11) LDTP12677 26.91  LDD1783 
DnaJ homolog subfamily C member 16 (DNAJC16) LDTP13863 20.11  LDD1783 
Dymeclin (DYM) LDTP08000 29.65  LDD1783 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 44.32  LDD1783 
ELMO domain-containing protein 2 (ELMOD2) LDTP17659 17.63  LDD1783 
Emerin (EMD) LDTP04356 21.86  LDD1783 
Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) LDTP10046 22.94  LDD1783 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 75.58  LDD1783 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 50.91  LDD1783 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 99.73  LDD1783 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 30.70  LDD1783 
Gamma-tubulin complex component 5 (TUBGCP5) LDTP10784 19.29  LDD1783 
Ganglioside GM2 activator (GM2A) LDTP02927 27.10  LDD1783 
Gem-associated protein 8 (GEMIN8) LDTP12746 29.45  LDD1783 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 21.56  LDD1783 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 41.07  LDD1783 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 51.63  LDD1783 
Golgi SNAP receptor complex member 2 (GOSR2) LDTP00397 44.02  LDD1783 
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 (GNG5) LDTP05054 25.11  LDD1783 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 34.78  LDD1783 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 17.51  LDD1783 
HIG1 domain family member 1A, mitochondrial (HIGD1A) LDTP13797 28.44  LDD1783 
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) LDTP05530 21.86  LDD1783 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 21.11  LDD1783 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 21.11  LDD1783 
Kinesin light chain 2 (KLC2) LDTP11695 39.67  LDD1783 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 36.76  LDD1783 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 64.45  LDD1783 
Lipase maturation factor 2 (LMF2) LDTP15887 18.38  LDD1783 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 39.67  LDD1783 
m-AAA protease-interacting protein 1, mitochondrial (MAIP1) LDTP09644 22.94  LDD1783 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 99.73  LDD1783 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 27.10  LDD1783 
Membralin (TMEM259) LDTP14939 44.94  LDD1783 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 59.71  LDD1783 
MICOS complex subunit MIC27 (APOOL) LDTP07718 19.97  LDD1783 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 57.28  LDD1783 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 55.33  LDD1783 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 76.11  LDD1783 
Mitoregulin (MTLN) LDTP09108 20.82  LDD1783 
Negative elongation factor C/D (NELFCD) LDTP08594 40.79  LDD1783 
Nucleobindin-1 (NUCB1) LDTP05375 40.50  LDD1783 
Nucleobindin-2 (NUCB2) LDTP05160 49.87  LDD1783 
Nurim (NRM) LDTP08606 17.15  LDD1783 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 31.56  LDD1783 
Optic atrophy 3 protein (OPA3) LDTP16006 35.75  LDD1783 
Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) LDTP11906 26.17  LDD1783 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 42.52  LDD1783 
PRELI domain containing protein 3B (PRELID3B) LDTP18569 33.13  LDD1783 
Protein CEBPZOS (CEBPZOS) LDTP18883 41.93  LDD1783 
Protein FAM114A2 (FAM114A2) LDTP16080 59.30  LDD1783 
Protein FAM136A (FAM136A) LDTP18132 30.27  LDD1783 
Protein FAM162A (FAM162A) LDTP10056 92.41  LDD1783 
Protein FAM177A1 (FAM177A1) LDTP15398 25.11  LDD1783 
Protein FAM3C (FAM3C) LDTP09773 51.27  LDD1783 
Protein jagunal homolog 1 (JAGN1) LDTP08904 34.54  LDD1783 
Protein LYRIC (MTDH) LDTP08224 41.07  LDD1783 
Protein NCBP2AS2 (NCBP2AS2) LDTP19472 19.16  LDD1783 
Protein SERAC1 (SERAC1) LDTP10487 18.77  LDD1783 
Protein SET (SET) LDTP05277 22.47  LDD1783 
Protein SYS1 homolog (SYS1) LDTP08796 28.44  LDD1783 
Protein unc-119 homolog A (UNC119) LDTP05868 23.26  LDD1783 
Protein YIF1A (YIF1A) LDTP01494 37.27  LDD1783 
Protein YIPF4 (YIPF4) LDTP11167 20.25  LDD1783 
Receptor expression-enhancing protein 2 (REEP2) LDTP11113 30.27  LDD1783 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 31.34  LDD1783 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 28.84  LDD1783 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 20.25  LDD1783 
Regulator of microtubule dynamics protein 3 (RMDN3) LDTP10849 16.91  LDD1783 
Reticulocalbin-2 (RCN2) LDTP06097 25.11  LDD1783 
Reticulon-2 (RTN2) LDTP01167 64.00  LDD1783 
Reticulon-3 (RTN3) LDTP01522 99.73  LDD1783 
Reticulon-4 (RTN4) LDTP12412 99.73  LDD1783 
RNA-binding protein Musashi homolog 2 (MSI2) LDTP10216 18.00  LDD1783 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 42.22  LDD1783 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 22.63  LDD1783 
Small integral membrane protein 11 (SMIM11) LDTP16980 26.91  LDD1783 
Spartin (SPART) LDTP08735 18.90  LDD1783 
Survival motor neuron protein (SMN1; SMN2) LDTP06587 16.68  LDD1783 
Synaptic vesicle glycoprotein 2A (SV2A) LDTP07934 20.39  LDD1783 
Syntaxin-10 (STX10) LDTP00986 30.70  LDD1783 
Syntaxin-18 (STX18) LDTP13086 41.07  LDD1783 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 17.15  LDD1783 
Tetraspanin-6 (TSPAN6) LDTP14458 99.73  LDD1783 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 23.75  LDD1783 
Tetratricopeptide repeat protein 21B (TTC21B) LDTP08073 26.17  LDD1783 
Thioredoxin domain-containing protein 15 (TXNDC15) LDTP10442 35.02  LDD1783 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 61.82  LDD1783 
TraB domain-containing protein (TRABD) LDTP19963 36.00  LDD1783 
Transmembrane emp24 domain-containing protein 5 (TMED5) LDTP13967 23.75  LDD1783 
Transmembrane protein 209 (TMEM209) LDTP18272 21.11  LDD1783 
Tumor protein D54 (TPD52L2) LDTP00759 16.80  LDD1783 
Ubiquilin-1 (UBQLN1) LDTP13626 17.75  LDD1783 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 39.95  LDD1783 
UPF0488 protein C8orf33 (C8orf33) LDTP12025 30.70  LDD1783 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 22.78  LDD1783 
Vimentin (VIM) LDTP02297 20.97  LDD1783 
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⏷ Show the Full List of 108 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1783 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587