Details of the Target

General Information of Target

Target ID LDTP15484
Target Name Saccharopine dehydrogenase-like oxidoreductase (SCCPDH)
Gene Name SCCPDH
Gene ID 51097
Synonyms
Saccharopine dehydrogenase-like oxidoreductase; EC 1.-.-.-
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPASQSRARARDRNNVLNRAEFLSLNQPPKGGPEPRSSGRKASGPSAQPPPAGDGARERR
QSQQLPEEDCMQLNPSFKGIAFNSLLAIDICMSKRLGVCAGRAASWASARSMVKLIGITG
HGIPWIGGTILCLVKSSTLAGQEVLMNLLLALLLDIMTVAGVQKLIKRRGPYETSPSLLD
YLTMDIYAFPAGHASRAAMVSKFFLSHLVLAVPLRVLLVLWALCVGLSRVMIGRHHVTDV
LSGFVIGYLQFRLVELVWMPSSTCQMLISAW
Target Bioclass
Enzyme
Family
Saccharopine dehydrogenase family
Uniprot ID
Q8NBX0
Ensemble ID
ENST00000366510.4
HGNC ID
HGNC:24275

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 24 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [2]
FBPP2
 Probe Info  		11.78  LDD0318  [3]
TH211
 Probe Info  		Y105(20.00); Y244(20.00); Y237(11.75); Y202(11.64)  LDD0260  [4]
STPyne
 Probe Info  		K228(6.23); K242(6.07)  LDD0277  [5]
BTD
 Probe Info  		C361(1.11)  LDD1700  [6]
Sulforaphane-probe2
 Probe Info  		2.26  LDD0160  [7]
Jackson_1
 Probe Info  		5.05  LDD0120  [8]
AHL-Pu-1
 Probe Info  		C238(4.18)  LDD0170  [9]
HPAP
 Probe Info  		3.58  LDD0064  [10]
HHS-482
 Probe Info  		Y105(1.02)  LDD0285  [11]
DBIA
 Probe Info  		C238(0.98)  LDD0078  [12]
4-Iodoacetamidophenylacetylene
 Probe Info  		C77(0.00); C98(0.00); C238(0.00)  LDD0038  [13]
IA-alkyne
 Probe Info  		N.A.  LDD0032  [14]
IPIAA_H
 Probe Info  		N.A.  LDD0030  [15]
IPIAA_L
 Probe Info  		N.A.  LDD0031  [15]
Lodoacetamide azide
 Probe Info  		C98(0.00); C77(0.00)  LDD0037  [13]
Compound 10
 Probe Info  		N.A.  LDD2216  [16]
Compound 11
 Probe Info  		N.A.  LDD2213  [16]
IPM
 Probe Info  		N.A.  LDD0005  [17]
TFBX
 Probe Info  		N.A.  LDD0148  [18]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [19]
W1
 Probe Info  		N.A.  LDD0236  [20]
AOyne
 Probe Info  		14.00  LDD0443  [21]
NAIA_5
 Probe Info  		N.A.  LDD2223  [22]
PAL-AfBPP Probe
Click To Hide/Show 122 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
PARPYnD
 Probe Info  		3.15  LDD0374  [23]
C002
 Probe Info  		6.63  LDD1712  [24]
C004
 Probe Info  		9.00  LDD1714  [24]
C011
 Probe Info  		6.23  LDD1720  [24]
C017
 Probe Info  		12.73  LDD1725  [24]
C022
 Probe Info  		12.04  LDD1728  [24]
C026
 Probe Info  		14.22  LDD1732  [24]
C040
 Probe Info  		9.78  LDD1740  [24]
C041
 Probe Info  		20.39  LDD1741  [24]
C059
 Probe Info  		10.48  LDD1756  [24]
C063
 Probe Info  		21.86  LDD1760  [24]
C064
 Probe Info  		8.06  LDD1761  [24]
C070
 Probe Info  		19.56  LDD1766  [24]
C082
 Probe Info  		16.56  LDD1774  [24]
C083
 Probe Info  		6.63  LDD1775  [24]
C085
 Probe Info  		17.63  LDD1777  [24]
C087
 Probe Info  		8.69  LDD1779  [24]
C091
 Probe Info  		12.47  LDD1782  [24]
C092
 Probe Info  		19.43  LDD1783  [24]
C107
 Probe Info  		7.89  LDD1794  [24]
C108
 Probe Info  		8.22  LDD1795  [24]
C130
 Probe Info  		14.62  LDD1812  [24]
C135
 Probe Info  		15.56  LDD1817  [24]
C141
 Probe Info  		12.38  LDD1823  [24]
C143
 Probe Info  		24.08  LDD1825  [24]
C145
 Probe Info  		13.55  LDD1827  [24]
C147
 Probe Info  		14.83  LDD1829  [24]
C153
 Probe Info  		15.03  LDD1834  [24]
C156
 Probe Info  		5.94  LDD1836  [24]
C158
 Probe Info  		16.11  LDD1838  [24]
C160
 Probe Info  		9.85  LDD1840  [24]
C166
 Probe Info  		6.73  LDD1846  [24]
C177
 Probe Info  		8.75  LDD1856  [24]
C178
 Probe Info  		16.68  LDD1857  [24]
C187
 Probe Info  		16.00  LDD1865  [24]
C193
 Probe Info  		16.56  LDD1869  [24]
C198
 Probe Info  		11.08  LDD1874  [24]
C201
 Probe Info  		31.78  LDD1877  [24]
C205
 Probe Info  		5.28  LDD1880  [24]
C206
 Probe Info  		19.97  LDD1881  [24]
C211
 Probe Info  		12.13  LDD1885  [24]
C212
 Probe Info  		15.45  LDD1886  [24]
C213
 Probe Info  		15.56  LDD1887  [24]
C214
 Probe Info  		19.97  LDD1888  [24]
C216
 Probe Info  		12.55  LDD1890  [24]
C217
 Probe Info  		9.06  LDD1891  [24]
C218
 Probe Info  		11.71  LDD1892  [24]
C222
 Probe Info  		9.38  LDD1896  [24]
C225
 Probe Info  		10.34  LDD1898  [24]
C226
 Probe Info  		13.36  LDD1899  [24]
C228
 Probe Info  		22.01  LDD1901  [24]
C229
 Probe Info  		10.85  LDD1902  [24]
C231
 Probe Info  		15.35  LDD1904  [24]
C233
 Probe Info  		20.25  LDD1906  [24]
C234
 Probe Info  		21.71  LDD1907  [24]
C235
 Probe Info  		36.50  LDD1908  [24]
C240
 Probe Info  		9.45  LDD1913  [24]
C243
 Probe Info  		13.00  LDD1916  [24]
C245
 Probe Info  		6.63  LDD1918  [24]
C252
 Probe Info  		14.42  LDD1925  [24]
C258
 Probe Info  		8.94  LDD1931  [24]
C269
 Probe Info  		9.00  LDD1939  [24]
C270
 Probe Info  		8.94  LDD1940  [24]
C271
 Probe Info  		7.67  LDD1941  [24]
C273
 Probe Info  		5.17  LDD1943  [24]
C274
 Probe Info  		6.36  LDD1944  [24]
C288
 Probe Info  		15.14  LDD1958  [24]
C290
 Probe Info  		14.22  LDD1960  [24]
C297
 Probe Info  		13.00  LDD1967  [24]
C299
 Probe Info  		10.56  LDD1968  [24]
C301
 Probe Info  		7.41  LDD1970  [24]
C303
 Probe Info  		5.54  LDD1972  [24]
C304
 Probe Info  		8.82  LDD1973  [24]
C310
 Probe Info  		8.28  LDD1977  [24]
C314
 Probe Info  		14.03  LDD1981  [24]
C320
 Probe Info  		6.11  LDD1986  [24]
C322
 Probe Info  		9.13  LDD1988  [24]
C326
 Probe Info  		11.16  LDD1990  [24]
C333
 Probe Info  		7.67  LDD1996  [24]
C339
 Probe Info  		10.41  LDD2002  [24]
C346
 Probe Info  		20.25  LDD2007  [24]
C347
 Probe Info  		12.38  LDD2008  [24]
C350
 Probe Info  		27.10  LDD2011  [24]
C353
 Probe Info  		8.17  LDD2014  [24]
C354
 Probe Info  		23.92  LDD2015  [24]
C355
 Probe Info  		66.26  LDD2016  [24]
C356
 Probe Info  		8.11  LDD2017  [24]
C357
 Probe Info  		8.22  LDD2018  [24]
C361
 Probe Info  		29.86  LDD2022  [24]
C362
 Probe Info  		28.25  LDD2023  [24]
C373
 Probe Info  		11.63  LDD2033  [24]
C378
 Probe Info  		7.84  LDD2037  [24]
C380
 Probe Info  		5.98  LDD2039  [24]
C386
 Probe Info  		8.34  LDD2045  [24]
C390
 Probe Info  		75.06  LDD2049  [24]
C392
 Probe Info  		11.88  LDD2051  [24]
C393
 Probe Info  		16.68  LDD2052  [24]
C396
 Probe Info  		15.67  LDD2055  [24]
C399
 Probe Info  		7.94  LDD2058  [24]
C407
 Probe Info  		11.24  LDD2064  [24]
C408
 Probe Info  		5.43  LDD2065  [24]
C416
 Probe Info  		5.66  LDD2071  [24]
C420
 Probe Info  		19.03  LDD2075  [24]
C424
 Probe Info  		7.94  LDD2079  [24]
C426
 Probe Info  		14.03  LDD2081  [24]
C429
 Probe Info  		13.55  LDD2084  [24]
C430
 Probe Info  		12.38  LDD2085  [24]
C431
 Probe Info  		16.45  LDD2086  [24]
C432
 Probe Info  		6.92  LDD2087  [24]
C433
 Probe Info  		16.00  LDD2088  [24]
FFF probe11
 Probe Info  		16.70  LDD0471  [25]
FFF probe13
 Probe Info  		14.52  LDD0475  [25]
FFF probe14
 Probe Info  		17.52  LDD0477  [25]
FFF probe2
 Probe Info  		18.75  LDD0463  [25]
FFF probe3
 Probe Info  		20.00  LDD0464  [25]
JN0003
 Probe Info  		20.00  LDD0469  [25]
AX-1
 Probe Info  		5.05  LDD0441  [26]
A-DA
 Probe Info  		2.20  LDD0142  [27]
AEA-DA
 Probe Info  		8.09  LDD0146  [27]
Alk-rapa
 Probe Info  		8.40  LDD0213  [28]
DA-2
 Probe Info  		N.A.  LDD0072  [29]
OEA-DA
 Probe Info  		20.00  LDD0046  [30]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0502  1-(Cyanoacetyl)piperidine MDA-MB-231 C361(0.46)  LDD2095  [6]
 LDCM0537  2-Cyano-N,N-dimethylacetamide MDA-MB-231 C361(0.80)  LDD2130  [6]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C361(0.81)  LDD2117  [6]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C361(1.12)  LDD2152  [6]
 LDCM0538  4-(Cyanoacetyl)morpholine MDA-MB-231 C361(0.54)  LDD2131  [6]
 LDCM0025  4SU-RNA DM93 C238(4.18)  LDD0170  [9]
 LDCM0026  4SU-RNA+native RNA DM93 C238(4.22)  LDD0171  [9]
 LDCM0176  9im MDA-MB-231 5.05  LDD0441  [26]
 LDCM0214  AC1 HEK-293T C238(1.41)  LDD0812  [12]
 LDCM0215  AC10 HEK-293T C238(0.77)  LDD0813  [12]
 LDCM0216  AC100 HEK-293T C238(1.13)  LDD0814  [12]
 LDCM0217  AC101 HEK-293T C238(0.98)  LDD0815  [12]
 LDCM0218  AC102 HEK-293T C238(1.02)  LDD0816  [12]
 LDCM0219  AC103 HEK-293T C238(1.09)  LDD0817  [12]
 LDCM0220  AC104 HEK-293T C238(1.09)  LDD0818  [12]
 LDCM0221  AC105 HEK-293T C238(0.96)  LDD0819  [12]
 LDCM0222  AC106 HEK-293T C238(0.98)  LDD0820  [12]
 LDCM0223  AC107 HEK-293T C238(1.08)  LDD0821  [12]
 LDCM0224  AC108 HEK-293T C238(0.95)  LDD0822  [12]
 LDCM0225  AC109 HEK-293T C238(1.04)  LDD0823  [12]
 LDCM0226  AC11 HEK-293T C238(0.81)  LDD0824  [12]
 LDCM0227  AC110 HEK-293T C238(1.37)  LDD0825  [12]
 LDCM0228  AC111 HEK-293T C238(1.49)  LDD0826  [12]
 LDCM0229  AC112 HEK-293T C238(1.28)  LDD0827  [12]
 LDCM0230  AC113 HEK-293T C238(1.09)  LDD0828  [12]
 LDCM0231  AC114 HEK-293T C238(0.97)  LDD0829  [12]
 LDCM0232  AC115 HEK-293T C238(1.13)  LDD0830  [12]
 LDCM0233  AC116 HEK-293T C238(1.13)  LDD0831  [12]
 LDCM0234  AC117 HEK-293T C238(1.34)  LDD0832  [12]
 LDCM0235  AC118 HEK-293T C238(1.26)  LDD0833  [12]
 LDCM0236  AC119 HEK-293T C238(1.24)  LDD0834  [12]
 LDCM0237  AC12 HEK-293T C238(0.75)  LDD0835  [12]
 LDCM0238  AC120 HEK-293T C238(1.17)  LDD0836  [12]
 LDCM0239  AC121 HEK-293T C238(1.30)  LDD0837  [12]
 LDCM0240  AC122 HEK-293T C238(1.41)  LDD0838  [12]
 LDCM0241  AC123 HEK-293T C238(1.52)  LDD0839  [12]
 LDCM0242  AC124 HEK-293T C238(1.27)  LDD0840  [12]
 LDCM0243  AC125 HEK-293T C238(1.32)  LDD0841  [12]
 LDCM0244  AC126 HEK-293T C238(1.63)  LDD0842  [12]
 LDCM0245  AC127 HEK-293T C238(1.84)  LDD0843  [12]
 LDCM0246  AC128 HEK-293T C238(1.12)  LDD0844  [12]
 LDCM0247  AC129 HEK-293T C238(1.10)  LDD0845  [12]
 LDCM0249  AC130 HEK-293T C238(1.22)  LDD0847  [12]
 LDCM0250  AC131 HEK-293T C238(1.12)  LDD0848  [12]
 LDCM0251  AC132 HEK-293T C238(1.08)  LDD0849  [12]
 LDCM0252  AC133 HEK-293T C238(1.18)  LDD0850  [12]
 LDCM0253  AC134 HEK-293T C238(1.19)  LDD0851  [12]
 LDCM0254  AC135 HEK-293T C238(1.20)  LDD0852  [12]
 LDCM0255  AC136 HEK-293T C238(0.98)  LDD0853  [12]
 LDCM0256  AC137 HEK-293T C238(1.19)  LDD0854  [12]
 LDCM0257  AC138 HEK-293T C238(1.43)  LDD0855  [12]
 LDCM0258  AC139 HEK-293T C238(1.37)  LDD0856  [12]
 LDCM0259  AC14 HEK-293T C238(0.84)  LDD0857  [12]
 LDCM0260  AC140 HEK-293T C238(1.18)  LDD0858  [12]
 LDCM0261  AC141 HEK-293T C238(1.22)  LDD0859  [12]
 LDCM0262  AC142 HEK-293T C238(1.25)  LDD0860  [12]
 LDCM0263  AC143 HEK-293T C238(1.19)  LDD0861  [12]
 LDCM0264  AC144 HEK-293T C238(1.18)  LDD0862  [12]
 LDCM0265  AC145 HEK-293T C238(1.52)  LDD0863  [12]
 LDCM0266  AC146 HEK-293T C238(1.47)  LDD0864  [12]
 LDCM0267  AC147 HEK-293T C238(1.51)  LDD0865  [12]
 LDCM0268  AC148 HEK-293T C238(1.34)  LDD0866  [12]
 LDCM0269  AC149 HEK-293T C238(0.98)  LDD0867  [12]
 LDCM0270  AC15 HEK-293T C238(0.86)  LDD0868  [12]
 LDCM0271  AC150 HEK-293T C238(1.17)  LDD0869  [12]
 LDCM0272  AC151 HEK-293T C238(1.19)  LDD0870  [12]
 LDCM0273  AC152 HEK-293T C238(0.94)  LDD0871  [12]
 LDCM0274  AC153 HEK-293T C238(0.99)  LDD0872  [12]
 LDCM0621  AC154 HEK-293T C238(0.87)  LDD2162  [12]
 LDCM0622  AC155 HEK-293T C238(1.07)  LDD2163  [12]
 LDCM0623  AC156 HEK-293T C238(1.27)  LDD2164  [12]
 LDCM0624  AC157 HEK-293T C238(1.25)  LDD2165  [12]
 LDCM0276  AC17 HEK-293T C238(1.57)  LDD0874  [12]
 LDCM0277  AC18 HEK-293T C238(1.43)  LDD0875  [12]
 LDCM0278  AC19 HEK-293T C238(1.15)  LDD0876  [12]
 LDCM0279  AC2 HEK-293T C238(1.16)  LDD0877  [12]
 LDCM0280  AC20 HEK-293T C238(1.47)  LDD0878  [12]
 LDCM0281  AC21 HEK-293T C238(1.26)  LDD0879  [12]
 LDCM0282  AC22 HEK-293T C238(1.34)  LDD0880  [12]
 LDCM0283  AC23 HEK-293T C238(1.75)  LDD0881  [12]
 LDCM0284  AC24 HEK-293T C238(1.18)  LDD0882  [12]
 LDCM0285  AC25 HEK-293T C238(1.06)  LDD0883  [12]
 LDCM0286  AC26 HEK-293T C238(1.19)  LDD0884  [12]
 LDCM0287  AC27 HEK-293T C238(1.23)  LDD0885  [12]
 LDCM0288  AC28 HEK-293T C238(0.98)  LDD0886  [12]
 LDCM0289  AC29 HEK-293T C238(1.08)  LDD0887  [12]
 LDCM0290  AC3 HEK-293T C238(1.11)  LDD0888  [12]
 LDCM0291  AC30 HEK-293T C238(1.09)  LDD0889  [12]
 LDCM0292  AC31 HEK-293T C238(0.97)  LDD0890  [12]
 LDCM0293  AC32 HEK-293T C238(0.99)  LDD0891  [12]
 LDCM0294  AC33 HEK-293T C238(1.08)  LDD0892  [12]
 LDCM0295  AC34 HEK-293T C238(0.99)  LDD0893  [12]
 LDCM0296  AC35 HEK-293T C238(1.05)  LDD0894  [12]
 LDCM0297  AC36 HEK-293T C238(1.04)  LDD0895  [12]
 LDCM0298  AC37 HEK-293T C238(1.01)  LDD0896  [12]
 LDCM0299  AC38 HEK-293T C238(1.00)  LDD0897  [12]
 LDCM0300  AC39 HEK-293T C238(1.12)  LDD0898  [12]
 LDCM0301  AC4 HEK-293T C238(0.98)  LDD0899  [12]
 LDCM0302  AC40 HEK-293T C238(1.09)  LDD0900  [12]
 LDCM0303  AC41 HEK-293T C238(1.19)  LDD0901  [12]
 LDCM0304  AC42 HEK-293T C238(1.16)  LDD0902  [12]
 LDCM0305  AC43 HEK-293T C238(1.11)  LDD0903  [12]
 LDCM0306  AC44 HEK-293T C238(1.16)  LDD0904  [12]
 LDCM0307  AC45 HEK-293T C238(1.12)  LDD0905  [12]
 LDCM0308  AC46 HEK-293T C238(1.05)  LDD0906  [12]
 LDCM0309  AC47 HEK-293T C238(1.03)  LDD0907  [12]
 LDCM0310  AC48 HEK-293T C238(1.12)  LDD0908  [12]
 LDCM0311  AC49 HEK-293T C238(1.04)  LDD0909  [12]
 LDCM0312  AC5 HEK-293T C238(1.10)  LDD0910  [12]
 LDCM0313  AC50 HEK-293T C238(1.19)  LDD0911  [12]
 LDCM0314  AC51 HEK-293T C238(1.13)  LDD0912  [12]
 LDCM0315  AC52 HEK-293T C238(1.08)  LDD0913  [12]
 LDCM0316  AC53 HEK-293T C238(1.03)  LDD0914  [12]
 LDCM0317  AC54 HEK-293T C238(1.19)  LDD0915  [12]
 LDCM0318  AC55 HEK-293T C238(1.26)  LDD0916  [12]
 LDCM0319  AC56 HEK-293T C238(1.06)  LDD0917  [12]
 LDCM0320  AC57 HEK-293T C238(1.09)  LDD0918  [12]
 LDCM0321  AC58 HEK-293T C238(1.03)  LDD0919  [12]
 LDCM0322  AC59 HEK-293T C238(0.92)  LDD0920  [12]
 LDCM0323  AC6 HEK-293T C238(1.04)  LDD0921  [12]
 LDCM0324  AC60 HEK-293T C238(1.32)  LDD0922  [12]
 LDCM0325  AC61 HEK-293T C238(1.46)  LDD0923  [12]
 LDCM0326  AC62 HEK-293T C238(0.99)  LDD0924  [12]
 LDCM0327  AC63 HEK-293T C238(1.13)  LDD0925  [12]
 LDCM0328  AC64 HEK-293T C238(1.02)  LDD0926  [12]
 LDCM0329  AC65 HEK-293T C238(1.05)  LDD0927  [12]
 LDCM0330  AC66 HEK-293T C238(1.00)  LDD0928  [12]
 LDCM0331  AC67 HEK-293T C238(1.04)  LDD0929  [12]
 LDCM0332  AC68 HEK-293T C238(1.12)  LDD0930  [12]
 LDCM0333  AC69 HEK-293T C238(1.11)  LDD0931  [12]
 LDCM0334  AC7 HEK-293T C238(1.01)  LDD0932  [12]
 LDCM0335  AC70 HEK-293T C238(1.10)  LDD0933  [12]
 LDCM0336  AC71 HEK-293T C238(1.14)  LDD0934  [12]
 LDCM0337  AC72 HEK-293T C238(1.17)  LDD0935  [12]
 LDCM0338  AC73 HEK-293T C238(1.26)  LDD0936  [12]
 LDCM0339  AC74 HEK-293T C238(1.30)  LDD0937  [12]
 LDCM0340  AC75 HEK-293T C238(1.23)  LDD0938  [12]
 LDCM0341  AC76 HEK-293T C238(1.15)  LDD0939  [12]
 LDCM0342  AC77 HEK-293T C238(1.02)  LDD0940  [12]
 LDCM0343  AC78 HEK-293T C238(1.11)  LDD0941  [12]
 LDCM0344  AC79 HEK-293T C238(1.03)  LDD0942  [12]
 LDCM0345  AC8 HEK-293T C238(1.14)  LDD0943  [12]
 LDCM0346  AC80 HEK-293T C238(1.15)  LDD0944  [12]
 LDCM0347  AC81 HEK-293T C238(1.92)  LDD0945  [12]
 LDCM0348  AC82 HEK-293T C238(1.14)  LDD0946  [12]
 LDCM0349  AC83 HEK-293T C238(0.99)  LDD0947  [12]
 LDCM0350  AC84 HEK-293T C238(1.00)  LDD0948  [12]
 LDCM0351  AC85 HEK-293T C238(0.93)  LDD0949  [12]
 LDCM0352  AC86 HEK-293T C238(0.92)  LDD0950  [12]
 LDCM0353  AC87 HEK-293T C238(0.90)  LDD0951  [12]
 LDCM0354  AC88 HEK-293T C238(1.01)  LDD0952  [12]
 LDCM0355  AC89 HEK-293T C238(1.00)  LDD0953  [12]
 LDCM0357  AC90 HEK-293T C238(0.93)  LDD0955  [12]
 LDCM0358  AC91 HEK-293T C238(0.83)  LDD0956  [12]
 LDCM0359  AC92 HEK-293T C238(0.96)  LDD0957  [12]
 LDCM0360  AC93 HEK-293T C238(0.86)  LDD0958  [12]
 LDCM0361  AC94 HEK-293T C238(0.98)  LDD0959  [12]
 LDCM0362  AC95 HEK-293T C238(0.91)  LDD0960  [12]
 LDCM0363  AC96 HEK-293T C238(0.88)  LDD0961  [12]
 LDCM0364  AC97 HEK-293T C238(1.11)  LDD0962  [12]
 LDCM0365  AC98 HEK-293T C238(0.97)  LDD0963  [12]
 LDCM0366  AC99 HEK-293T C238(0.99)  LDD0964  [12]
 LDCM0545  Acetamide MDA-MB-231 C361(0.35)  LDD2138  [6]
 LDCM0520  AKOS000195272 MDA-MB-231 C361(0.73)  LDD2113  [6]
 LDCM0248  AKOS034007472 HEK-293T C238(0.97)  LDD0846  [12]
 LDCM0356  AKOS034007680 HEK-293T C238(0.77)  LDD0954  [12]
 LDCM0275  AKOS034007705 HEK-293T C238(0.92)  LDD0873  [12]
 LDCM0156  Aniline NCI-H1299 12.10  LDD0403  [2]
 LDCM0020  ARS-1620 HCC44 C238(0.98)  LDD0078  [12]
 LDCM0083  Avasimibe A-549 3.38  LDD0143  [27]
 LDCM0147  AZ0108 MDA-MB-468 2.11  LDD0376  [23]
 LDCM0200  BPK-25 T cell C238(17.60)  LDD0516  [31]
 LDCM0498  BS-3668 MDA-MB-231 C361(0.49)  LDD2091  [6]
 LDCM0070  Cisar_cp37 MDA-MB-231 5.05  LDD0120  [8]
 LDCM0367  CL1 HEK-293T C238(0.82)  LDD0965  [12]
 LDCM0368  CL10 HEK-293T C238(1.25)  LDD0966  [12]
 LDCM0369  CL100 HEK-293T C238(1.21)  LDD0967  [12]
 LDCM0370  CL101 HEK-293T C238(1.41)  LDD0968  [12]
 LDCM0371  CL102 HEK-293T C238(1.41)  LDD0969  [12]
 LDCM0372  CL103 HEK-293T C238(0.92)  LDD0970  [12]
 LDCM0373  CL104 HEK-293T C238(1.22)  LDD0971  [12]
 LDCM0374  CL105 HEK-293T C238(1.24)  LDD0972  [12]
 LDCM0375  CL106 HEK-293T C238(1.30)  LDD0973  [12]
 LDCM0376  CL107 HEK-293T C238(1.25)  LDD0974  [12]
 LDCM0377  CL108 HEK-293T C238(1.31)  LDD0975  [12]
 LDCM0378  CL109 HEK-293T C238(1.28)  LDD0976  [12]
 LDCM0379  CL11 HEK-293T C238(1.25)  LDD0977  [12]
 LDCM0380  CL110 HEK-293T C238(1.42)  LDD0978  [12]
 LDCM0381  CL111 HEK-293T C238(1.27)  LDD0979  [12]
 LDCM0382  CL112 HEK-293T C238(1.16)  LDD0980  [12]
 LDCM0383  CL113 HEK-293T C238(1.00)  LDD0981  [12]
 LDCM0384  CL114 HEK-293T C238(1.39)  LDD0982  [12]
 LDCM0385  CL115 HEK-293T C238(1.05)  LDD0983  [12]
 LDCM0386  CL116 HEK-293T C238(1.13)  LDD0984  [12]
 LDCM0387  CL117 HEK-293T C238(1.01)  LDD0985  [12]
 LDCM0388  CL118 HEK-293T C238(1.14)  LDD0986  [12]
 LDCM0389  CL119 HEK-293T C238(1.07)  LDD0987  [12]
 LDCM0390  CL12 HEK-293T C238(0.93)  LDD0988  [12]
 LDCM0391  CL120 HEK-293T C238(1.19)  LDD0989  [12]
 LDCM0392  CL121 HEK-293T C238(1.28)  LDD0990  [12]
 LDCM0393  CL122 HEK-293T C238(1.19)  LDD0991  [12]
 LDCM0394  CL123 HEK-293T C238(1.06)  LDD0992  [12]
 LDCM0395  CL124 HEK-293T C238(1.20)  LDD0993  [12]
 LDCM0396  CL125 HEK-293T C238(1.08)  LDD0994  [12]
 LDCM0397  CL126 HEK-293T C238(1.14)  LDD0995  [12]
 LDCM0398  CL127 HEK-293T C238(1.07)  LDD0996  [12]
 LDCM0399  CL128 HEK-293T C238(1.04)  LDD0997  [12]
 LDCM0400  CL13 HEK-293T C238(0.91)  LDD0998  [12]
 LDCM0401  CL14 HEK-293T C238(0.92)  LDD0999  [12]
 LDCM0402  CL15 HEK-293T C238(1.17)  LDD1000  [12]
 LDCM0403  CL16 HEK-293T C238(1.01)  LDD1001  [12]
 LDCM0404  CL17 HEK-293T C238(2.10)  LDD1002  [12]
 LDCM0405  CL18 HEK-293T C238(1.23)  LDD1003  [12]
 LDCM0406  CL19 HEK-293T C238(1.14)  LDD1004  [12]
 LDCM0407  CL2 HEK-293T C238(0.94)  LDD1005  [12]
 LDCM0408  CL20 HEK-293T C238(1.07)  LDD1006  [12]
 LDCM0409  CL21 HEK-293T C238(1.82)  LDD1007  [12]
 LDCM0410  CL22 HEK-293T C238(1.22)  LDD1008  [12]
 LDCM0411  CL23 HEK-293T C238(1.01)  LDD1009  [12]
 LDCM0412  CL24 HEK-293T C238(1.14)  LDD1010  [12]
 LDCM0413  CL25 HEK-293T C238(1.56)  LDD1011  [12]
 LDCM0414  CL26 HEK-293T C238(1.05)  LDD1012  [12]
 LDCM0415  CL27 HEK-293T C238(1.10)  LDD1013  [12]
 LDCM0416  CL28 HEK-293T C238(1.15)  LDD1014  [12]
 LDCM0417  CL29 HEK-293T C238(1.04)  LDD1015  [12]
 LDCM0418  CL3 HEK-293T C238(0.89)  LDD1016  [12]
 LDCM0419  CL30 HEK-293T C238(1.26)  LDD1017  [12]
 LDCM0420  CL31 HEK-293T C238(0.96)  LDD1018  [12]
 LDCM0421  CL32 HEK-293T C238(1.09)  LDD1019  [12]
 LDCM0422  CL33 HEK-293T C238(1.30)  LDD1020  [12]
 LDCM0423  CL34 HEK-293T C238(1.22)  LDD1021  [12]
 LDCM0424  CL35 HEK-293T C238(1.01)  LDD1022  [12]
 LDCM0425  CL36 HEK-293T C238(1.02)  LDD1023  [12]
 LDCM0426  CL37 HEK-293T C238(1.02)  LDD1024  [12]
 LDCM0428  CL39 HEK-293T C238(1.30)  LDD1026  [12]
 LDCM0429  CL4 HEK-293T C238(1.18)  LDD1027  [12]
 LDCM0430  CL40 HEK-293T C238(1.00)  LDD1028  [12]
 LDCM0431  CL41 HEK-293T C238(1.46)  LDD1029  [12]
 LDCM0432  CL42 HEK-293T C238(1.31)  LDD1030  [12]
 LDCM0433  CL43 HEK-293T C238(1.28)  LDD1031  [12]
 LDCM0434  CL44 HEK-293T C238(0.97)  LDD1032  [12]
 LDCM0435  CL45 HEK-293T C238(1.20)  LDD1033  [12]
 LDCM0436  CL46 HEK-293T C238(1.04)  LDD1034  [12]
 LDCM0437  CL47 HEK-293T C238(1.05)  LDD1035  [12]
 LDCM0438  CL48 HEK-293T C238(1.01)  LDD1036  [12]
 LDCM0439  CL49 HEK-293T C238(1.12)  LDD1037  [12]
 LDCM0440  CL5 HEK-293T C238(1.00)  LDD1038  [12]
 LDCM0441  CL50 HEK-293T C238(1.39)  LDD1039  [12]
 LDCM0442  CL51 HEK-293T C238(1.30)  LDD1040  [12]
 LDCM0443  CL52 HEK-293T C238(0.98)  LDD1041  [12]
 LDCM0444  CL53 HEK-293T C238(1.86)  LDD1042  [12]
 LDCM0445  CL54 HEK-293T C238(1.40)  LDD1043  [12]
 LDCM0446  CL55 HEK-293T C238(1.17)  LDD1044  [12]
 LDCM0447  CL56 HEK-293T C238(1.04)  LDD1045  [12]
 LDCM0448  CL57 HEK-293T C238(1.04)  LDD1046  [12]
 LDCM0449  CL58 HEK-293T C238(1.07)  LDD1047  [12]
 LDCM0450  CL59 HEK-293T C238(1.27)  LDD1048  [12]
 LDCM0451  CL6 HEK-293T C238(1.00)  LDD1049  [12]
 LDCM0452  CL60 HEK-293T C238(1.24)  LDD1050  [12]
 LDCM0453  CL61 HEK-293T C238(0.95)  LDD1051  [12]
 LDCM0454  CL62 HEK-293T C238(1.07)  LDD1052  [12]
 LDCM0455  CL63 HEK-293T C238(1.13)  LDD1053  [12]
 LDCM0456  CL64 HEK-293T C238(1.26)  LDD1054  [12]
 LDCM0457  CL65 HEK-293T C238(1.13)  LDD1055  [12]
 LDCM0458  CL66 HEK-293T C238(1.18)  LDD1056  [12]
 LDCM0459  CL67 HEK-293T C238(1.03)  LDD1057  [12]
 LDCM0460  CL68 HEK-293T C238(1.10)  LDD1058  [12]
 LDCM0461  CL69 HEK-293T C238(1.06)  LDD1059  [12]
 LDCM0462  CL7 HEK-293T C238(1.05)  LDD1060  [12]
 LDCM0463  CL70 HEK-293T C238(0.97)  LDD1061  [12]
 LDCM0464  CL71 HEK-293T C238(1.08)  LDD1062  [12]
 LDCM0465  CL72 HEK-293T C238(0.95)  LDD1063  [12]
 LDCM0466  CL73 HEK-293T C238(1.39)  LDD1064  [12]
 LDCM0467  CL74 HEK-293T C238(1.33)  LDD1065  [12]
 LDCM0469  CL76 HEK-293T C238(0.82)  LDD1067  [12]
 LDCM0470  CL77 HEK-293T C238(0.84)  LDD1068  [12]
 LDCM0471  CL78 HEK-293T C238(0.62)  LDD1069  [12]
 LDCM0472  CL79 HEK-293T C238(0.72)  LDD1070  [12]
 LDCM0473  CL8 HEK-293T C238(0.81)  LDD1071  [12]
 LDCM0474  CL80 HEK-293T C238(0.78)  LDD1072  [12]
 LDCM0475  CL81 HEK-293T C238(0.78)  LDD1073  [12]
 LDCM0476  CL82 HEK-293T C238(0.95)  LDD1074  [12]
 LDCM0477  CL83 HEK-293T C238(0.92)  LDD1075  [12]
 LDCM0478  CL84 HEK-293T C238(0.73)  LDD1076  [12]
 LDCM0479  CL85 HEK-293T C238(0.72)  LDD1077  [12]
 LDCM0480  CL86 HEK-293T C238(0.70)  LDD1078  [12]
 LDCM0481  CL87 HEK-293T C238(0.73)  LDD1079  [12]
 LDCM0482  CL88 HEK-293T C238(0.89)  LDD1080  [12]
 LDCM0483  CL89 HEK-293T C238(0.78)  LDD1081  [12]
 LDCM0484  CL9 HEK-293T C238(0.80)  LDD1082  [12]
 LDCM0485  CL90 HEK-293T C238(1.16)  LDD1083  [12]
 LDCM0486  CL91 HEK-293T C238(1.16)  LDD1084  [12]
 LDCM0487  CL92 HEK-293T C238(0.94)  LDD1085  [12]
 LDCM0488  CL93 HEK-293T C238(1.03)  LDD1086  [12]
 LDCM0489  CL94 HEK-293T C238(1.16)  LDD1087  [12]
 LDCM0490  CL95 HEK-293T C238(3.00)  LDD1088  [12]
 LDCM0491  CL96 HEK-293T C238(1.45)  LDD1089  [12]
 LDCM0492  CL97 HEK-293T C238(1.45)  LDD1090  [12]
 LDCM0493  CL98 HEK-293T C238(1.05)  LDD1091  [12]
 LDCM0494  CL99 HEK-293T C238(0.98)  LDD1092  [12]
 LDCM0495  E2913 HEK-293T C238(1.38); C113(0.86)  LDD1698  [32]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C98(1.80); C238(1.33)  LDD1702  [6]
 LDCM0082  FK866 A-549 2.20  LDD0142  [27]
 LDCM0573  Fragment11 MDA-MB-231 C238(20.00)  LDD1391  [33]
 LDCM0576  Fragment14 MDA-MB-231 C238(1.72)  LDD1397  [33]
 LDCM0578  Fragment27 MDA-MB-231 C238(1.22)  LDD1413  [33]
 LDCM0468  Fragment33 HEK-293T C238(1.16)  LDD1066  [12]
 LDCM0427  Fragment51 HEK-293T C238(1.05)  LDD1025  [12]
 LDCM0123  JWB131 DM93 Y105(1.02)  LDD0285  [11]
 LDCM0124  JWB142 DM93 Y105(0.92)  LDD0286  [11]
 LDCM0125  JWB146 DM93 Y105(1.84)  LDD0287  [11]
 LDCM0126  JWB150 DM93 Y105(3.20)  LDD0288  [11]
 LDCM0127  JWB152 DM93 Y105(2.64)  LDD0289  [11]
 LDCM0128  JWB198 DM93 Y105(1.32)  LDD0290  [11]
 LDCM0129  JWB202 DM93 Y105(0.69)  LDD0291  [11]
 LDCM0130  JWB211 DM93 Y105(1.49)  LDD0292  [11]
 LDCM0022  KB02 HCT 116 C238(11.77)  LDD0080  [12]
 LDCM0023  KB03 HCT 116 C238(1.27)  LDD0081  [12]
 LDCM0024  KB05 HCT 116 C238(2.30)  LDD0082  [12]
 LDCM0528  N-(4-bromophenyl)-2-cyano-N-phenylacetamide MDA-MB-231 C361(0.46)  LDD2121  [6]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C361(0.57)  LDD2089  [6]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C361(0.82)  LDD2093  [6]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C361(0.64)  LDD2099  [6]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C361(0.75)  LDD2101  [6]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C361(0.74)  LDD2107  [6]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C361(0.80)  LDD2111  [6]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C361(0.86); C98(0.81)  LDD2123  [6]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C361(0.75)  LDD2125  [6]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C361(0.89); C98(0.93)  LDD2127  [6]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C361(0.94)  LDD2129  [6]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C361(0.47)  LDD2134  [6]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C98(1.67)  LDD2136  [6]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C361(0.87); C98(0.91)  LDD2137  [6]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C361(1.11)  LDD1700  [6]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C361(0.70)  LDD2141  [6]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C361(3.77)  LDD2145  [6]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C361(0.54)  LDD2148  [6]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C361(0.43)  LDD2150  [6]
 LDCM0014  Panhematin hPBMC 3.58  LDD0064  [10]
 LDCM0090  Rapamycin JHH-7 8.40  LDD0213  [28]
 LDCM0084  Ro 48-8071 A-549 4.14  LDD0145  [27]
 LDCM0003  Sulforaphane MDA-MB-231 2.26  LDD0160  [7]
 LDCM0112  W16 Hep-G2 C238(3.54)  LDD0239  [20]
 LDCM0113  W17 Hep-G2 C238(11.76)  LDD0240  [20]

References

1 Labeling Preferences of Diazirines with Protein Biomolecules. J Am Chem Soc. 2021 May 5;143(17):6691-6700. doi: 10.1021/jacs.1c02509. Epub 2021 Apr 20.
Mass spectrometry data entry: PXD025140
2 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
3 Tranylcypromine specificity for monoamine oxidase is limited by promiscuous protein labelling and lysosomal trapping. RSC Chem Biol. 2020 Aug 12;1(4):209-213. doi: 10.1039/d0cb00048e. eCollection 2020 Oct 1.
Mass spectrometry data entry: PXD018580
4 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
5 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
6 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
7 Competition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphane. Chem Commun (Camb). 2017 May 4;53(37):5182-5185. doi: 10.1039/c6cc08797c.
Mass spectrometry data entry: PXD006279
8 Appendage and Scaffold Diverse Fully Functionalized Small-Molecule Probes via a Minimalist Terminal Alkyne-Aliphatic Diazirine Isocyanide. J Org Chem. 2018 Sep 21;83(18):11245-11253. doi: 10.1021/acs.joc.8b01831. Epub 2018 Aug 31.
9 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
10 A Chemical Proteomic Map of Heme-Protein Interactions. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12.
Mass spectrometry data entry: PXD034651
11 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
12 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
13 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
14 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
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Mass spectrometry data entry: PXD029500 , PXD031647
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Mass spectrometry data entry: PXD029255
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Mass spectrometry data entry: PXD033004
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Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD007570
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