Probe Name	DA-2					Probe Info
Probe concentration	10 uM
Criteria	Other data
In Vivo Experiment Model	Model Type			Cell lysate
	Derived Tissue			Liver
	Disease Model		Hepatoblastoma [ICD-11:DB91]
	Model Name		Human hepatoblastoma cell lysate (Hep-G2)

Target ID	Target Name
LDTP06286	116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2)
LDTP10404	2-oxoadipate dehydrogenase complex component E1 (DHTKD1)
LDTP05341	2-oxoglutarate dehydrogenase complex component E1 (OGDH)
LDTP00224	26S proteasome non-ATPase regulatory subunit 12 (PSMD12)
LDTP00294	26S proteasome non-ATPase regulatory subunit 14 (PSMD14)
LDTP04987	26S proteasome regulatory subunit 10B (PSMC6)
LDTP03611	3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH)
LDTP03998	3-ketoacyl-CoA thiolase, mitochondrial (ACAA2)
LDTP04232	4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1)
LDTP04499	6-phosphogluconate dehydrogenase, decarboxylating (PGD)
LDTP10982	Aconitate hydratase, mitochondrial (ACO2)
LDTP04636	Adenylate kinase 2, mitochondrial (AK2)
LDTP11127	ADP-dependent glucokinase (ADPGK)
LDTP04262	Alanine--tRNA ligase, cytoplasmic (AARS1)
LDTP15371	Aldehyde dehydrogenase family 16 member A1 (ALDH16A1)
LDTP02765	Aldo-keto reductase family 1 member B1 (AKR1B1)
LDTP05436	Aldo-keto reductase family 1 member C1 (AKR1C1)
LDTP02514	Alkaline phosphatase, germ cell type (ALPG)
LDTP02100	Alkaline phosphatase, placental type (ALPP)
LDTP00186	Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS)
LDTP04253	Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1)
LDTP15993	Aminopeptidase B (RNPEP)
LDTP01687	Apoptosis-inducing factor 1, mitochondrial (AIFM1)
LDTP04601	Arginine--tRNA ligase, cytoplasmic (RARS1)
LDTP01807	Argininosuccinate synthase (ASS1)
LDTP00866	Asparagine--tRNA ligase, cytoplasmic (NARS1)
LDTP02752	Aspartate--tRNA ligase, cytoplasmic (DARS1)
LDTP03424	ATP-binding cassette sub-family D member 3 (ABCD3)
LDTP02925	ATP-dependent 6-phosphofructokinase, liver type (PFKL)
LDTP05314	ATP-dependent 6-phosphofructokinase, platelet type (PFKP)
LDTP09766	ATP-dependent RNA helicase DDX1 (DDX1)
LDTP00684	ATP-dependent RNA helicase DHX15 (DHX15)
LDTP12681	ATPase family AAA domain-containing protein 3A (ATAD3A)
LDTP02216	Beta-hexosaminidase subunit beta (HEXB)
LDTP01564	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2)
LDTP02222	Bifunctional glutamate/proline--tRNA ligase (EPRS1)
LDTP04552	Biliverdin reductase A (BLVRA)
LDTP02580	C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1)
LDTP02831	Carbonyl reductase [NADPH] 1 (CBR1)
LDTP01321	Carbonyl reductase [NADPH] 3 (CBR3)
LDTP03257	Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2)
LDTP02001	Catalase (CAT)
LDTP03145	Catechol O-methyltransferase (COMT)
LDTP12048	Complex I assembly factor ACAD9, mitochondrial (ACAD9)
LDTP05949	Cullin-4A (CUL4A)
LDTP08296	Cullin-associated NEDD8-dissociated protein 1 (CAND1)
LDTP05507	Cyclin-dependent kinase 18 (CDK18)
LDTP04263	Cysteine--tRNA ligase, cytoplasmic (CARS1)
LDTP00697	Cytochrome b5 type B (CYB5B)
LDTP02283	Cytochrome c1, heme protein, mitochondrial (CYC1)
LDTP05724	Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1)
LDTP04646	Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1)
LDTP13941	Deoxyribose-phosphate aldolase (DERA)
LDTP02497	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (DLAT)
LDTP03829	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (DLST)
LDTP03398	DNA repair nuclease/redox regulator APEX1 (APEX1)
LDTP03316	DNA replication licensing factor MCM3 (MCM3)
LDTP03680	DNA replication licensing factor MCM4 (MCM4)
LDTP06150	DNA replication licensing factor MCM6 (MCM6)
LDTP03682	DNA replication licensing factor MCM7 (MCM7)
LDTP02568	DNA topoisomerase 2-alpha (TOP2A)
LDTP05136	DNA-dependent protein kinase catalytic subunit (PRKDC)
LDTP03564	DNA-directed RNA polymerase II subunit RPB2 (POLR2B)
LDTP01047	Dolichol-phosphate mannosyltransferase subunit 1 (DPM1)
LDTP06098	E3 ubiquitin/ISG15 ligase TRIM25 (TRIM25)
LDTP05460	Elongation factor 1-alpha 2 (EEF1A2)
LDTP03518	Enoyl-CoA hydratase, mitochondrial (ECHS1)
LDTP06089	Eukaryotic initiation factor 4A-II (EIF4A2)
LDTP01634	Fatty acid CoA ligase Acsl3 (ACSL3)
LDTP03872	Flap endonuclease 1 (FEN1)
LDTP02386	Fructose-bisphosphate aldolase C (ALDOC)
LDTP13471	General transcription factor 3C polypeptide 4 (GTF3C4)
LDTP04032	Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD2)
LDTP03537	Glycylpeptide N-tetradecanoyltransferase 1 (NMT1)
LDTP13909	Guanine deaminase (GDA)
LDTP01061	H/ACA ribonucleoprotein complex subunit DKC1 (DKC1)
LDTP12233	Helicase MOV-10 (MOV10)
LDTP06645	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH)
LDTP03794	Hydroxymethylglutaryl-CoA lyase, mitochondrial (HMGCL)
LDTP07762	Hydroxysteroid dehydrogenase-like protein 2 (HSDL2)
LDTP11842	Inorganic pyrophosphatase 2, mitochondrial (PPA2)
LDTP02611	Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2)
LDTP03003	Interferon-induced, double-stranded RNA-activated protein kinase (EIF2AK2)
LDTP04345	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A)
LDTP03947	Isoleucine--tRNA ligase, cytoplasmic (IARS1)
LDTP16025	Ketosamine-3-kinase (FN3KRP)
LDTP06615	Kynureninase (KYNU)
LDTP13056	Leucine--tRNA ligase, cytoplasmic (LARS1)
LDTP03817	Lon protease homolog, mitochondrial (LONP1)
LDTP00496	Long-chain fatty acid transport protein 2 (SLC27A2)
LDTP00982	Long-chain-fatty-acid--CoA ligase 4 (ACSL4)
LDTP04229	MAP kinase-activated protein kinase 2 (MAPKAPK2)
LDTP02565	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM)
LDTP04730	Methionine--tRNA ligase, cytoplasmic (MARS1)
LDTP12227	Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2)
LDTP05632	Mitochondrial-processing peptidase subunit alpha (PMPCA)
LDTP08050	Myosin-14 (MYH14)
LDTP02798	NAD(P)H dehydrogenase [quinone] 1 (NQO1)
LDTP03891	Nicotinamide N-methyltransferase (NNMT)
LDTP02796	Nucleoside diphosphate kinase A (NME1)
LDTP12428	Omega-amidase NIT2 (NIT2)
LDTP03216	Peptidyl-prolyl cis-trans isomerase B (PPIB)
LDTP04440	Peroxisomal multifunctional enzyme type 2 (HSD17B4)
LDTP12586	Phenylalanine--tRNA ligase beta subunit (FARSB)
LDTP03818	Phosphoglucomutase-1 (PGM1)
LDTP01787	Phosphoglycerate kinase 1 (PGK1)
LDTP00527	Phosphoribosylformylglycinamidine synthase (PFAS)
LDTP14198	Phosphoserine aminotransferase (PSAT1)
LDTP02375	Poly [ADP-ribose] polymerase 1 (PARP1)
LDTP15391	Probable phosphoglycerate mutase 4 (PGAM4)
LDTP13750	Proliferation-associated protein 2G4 (PA2G4)
LDTP12040	Prostaglandin E synthase 2 (PTGES2)
LDTP03331	Proteasome subunit alpha type-2 (PSMA2)
LDTP03419	Proteasome subunit beta type-5 (PSMB5)
LDTP02638	Proto-oncogene tyrosine-protein kinase Src (SRC)
LDTP04712	Puromycin-sensitive aminopeptidase (NPEPPS)
LDTP00343	Pyridoxal kinase (PDXK)
LDTP03644	Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1)
LDTP02733	Pyruvate kinase PKM (PKM)
LDTP06501	Ras-related protein Rab-11B (RAB11B)
LDTP03231	Receptor-type tyrosine-protein phosphatase beta (PTPRB)
LDTP16032	Retinoid-inducible serine carboxypeptidase (SCPEP1)
LDTP09364	Retinol dehydrogenase 11 (RDH11)
LDTP04882	Ribose-phosphate pyrophosphokinase 1 (PRPS1)
LDTP02592	Ribose-phosphate pyrophosphokinase 2 (PRPS2)
LDTP04471	Ribosomal protein S6 kinase alpha-3 (RPS6KA3)
LDTP05588	RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2)
LDTP03155	rRNA 2'-O-methyltransferase fibrillarin (FBL)
LDTP15484	Saccharopine dehydrogenase-like oxidoreductase (SCCPDH)
LDTP02860	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2)
LDTP06279	Septin-2 (SEPTIN2)
LDTP02208	Serine protease 1 (PRSS1)
LDTP00299	Serine/threonine-protein kinase 25 (STK25)
LDTP03522	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A)
LDTP03819	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PPP1CC)
LDTP03769	Sterol O-acyltransferase 1 (SOAT1)
LDTP04715	Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (OXCT1)
LDTP14278	Sulfide:quinone oxidoreductase, mitochondrial (SQOR)
LDTP11874	Thioredoxin-related transmembrane protein 1 (TMX1)
LDTP06620	Thiosulfate sulfurtransferase (TST)
LDTP04665	Transitional endoplasmic reticulum ATPase (VCP)
LDTP03912	Trifunctional enzyme subunit alpha, mitochondrial (HADHA)
LDTP04617	Tyrosine--tRNA ligase, cytoplasmic (YARS1)
LDTP02139	Tyrosine-protein kinase Fyn (FYN)
LDTP02293	Tyrosine-protein kinase HCK (HCK)
LDTP02232	Tyrosine-protein kinase Lyn (LYN)
LDTP02231	Tyrosine-protein kinase Yes (YES1)
LDTP01283	U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200)
LDTP12851	UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1)
LDTP05708	Unconventional myosin-Ie (MYO1E)
LDTP11571	Uridine-cytidine kinase 2 (UCK2)
LDTP12954	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3)
LDTP12867	Very-long-chain enoyl-CoA reductase (TECR)
LDTP02642	X-ray repair cross-complementing protein 5 (XRCC5)
LDTP02640	X-ray repair cross-complementing protein 6 (XRCC6)

Target ID	Target Name
LDTP02608	ADP/ATP translocase 1 (SLC25A4)
LDTP02609	ADP/ATP translocase 3 (SLC25A6)
LDTP05625	AP-1 complex subunit beta-1 (AP1B1)
LDTP05038	AP-2 complex subunit beta (AP2B1)
LDTP03810	ATP synthase subunit gamma, mitochondrial (ATP5F1C)
LDTP09149	ATP-binding cassette sub-family F member 1 (ABCF1)
LDTP16103	ATP-binding cassette sub-family F member 3 (ABCF3)
LDTP05165	Brain acid soluble protein 1 (BASP1)
LDTP13599	Calcium load-activated calcium channel (TMCO1)
LDTP13393	Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13)
LDTP00501	Exportin-1 (XPO1)
LDTP00810	Exportin-T (XPOT)
LDTP11161	Extended synaptotagmin-1 (ESYT1)
LDTP02929	Galectin-3 (LGALS3)
LDTP11877	Golgi resident protein GCP60 (ACBD3)
LDTP01574	Importin-7 (IPO7)
LDTP10663	Importin-9 (IPO9)
LDTP05303	Interferon-induced transmembrane protein 2 (IFITM2)
LDTP10081	Leucine-rich repeat-containing protein 59 (LRRC59)
LDTP05384	Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11)
LDTP08279	Mitochondrial coenzyme A transporter SLC25A42 (SLC25A42)
LDTP05591	Nuclear cap-binding protein subunit 1 (NCBP1)
LDTP01295	Nuclear pore complex protein Nup155 (NUP155)
LDTP08769	Nuclear pore complex protein Nup93 (NUP93)
LDTP09502	Nuclear pore membrane glycoprotein 210 (NUP210)
LDTP04237	Protein ERGIC-53 (LMAN1)
LDTP00451	Secretory carrier-associated membrane protein 3 (SCAMP3)
LDTP10731	Sodium-coupled neutral amino acid symporter 2 (SLC38A2)
LDTP14636	Solute carrier family 25 member 16 (SLC25A16)
LDTP05238	Solute carrier family 25 member 3 (SLC25A3)
LDTP05273	Spectrin beta chain, non-erythrocytic 1 (SPTBN1)
LDTP00592	Surfeit locus protein 4 (SURF4)
LDTP04293	Transmembrane emp24 domain-containing protein 10 (TMED10)
LDTP04787	Transmembrane protein 33 (TMEM33)
LDTP04553	Tricarboxylate transport protein, mitochondrial (SLC25A1)
LDTP00196	Unconventional myosin-Ic (MYO1C)
LDTP10741	Vacuolar protein sorting-associated protein 35 (VPS35)
LDTP12966	Vesicle-associated membrane protein-associated protein A (VAPA)

Target ID	Target Name
LDTP02343	High mobility group protein B1 (HMGB1)
LDTP01414	Metastasis-associated protein MTA2 (MTA2)
LDTP06341	Non-POU domain-containing octamer-binding protein (NONO)
LDTP05254	Nuclear factor NF-kappa-B p100 subunit (NFKB2)
LDTP03969	Signal transducer and activator of transcription 1-alpha/beta (STAT1)
LDTP03903	Signal transducer and activator of transcription 3 (STAT3)
LDTP03601	Transcription factor HIVEP2 (HIVEP2)

Target ID	Target Name
LDTP01913	HLA class I histocompatibility antigen, B alpha chain (HLA-B)

Target ID	Target Name
LDTP03618	14-3-3 protein sigma (SFN)
LDTP06273	26S proteasome non-ATPase regulatory subunit 6 (PSMD6)
LDTP03871	Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A)
LDTP03612	Bifunctional purine biosynthesis protein ATIC (ATIC)
LDTP09365	Cancer-associated gene 1 protein (CAGE1)
LDTP08760	Cell cycle and apoptosis regulator protein 2 (CCAR2)
LDTP04571	Coatomer subunit alpha (COPA)
LDTP04570	Coatomer subunit beta (COPB1)
LDTP14216	Coatomer subunit gamma-1 (COPG1)
LDTP13110	Coatomer subunit gamma-2 (COPG2)
LDTP01195	Core histone macro-H2A.1 (MACROH2A1)
LDTP06083	Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1)
LDTP06543	DNA damage-binding protein 1 (DDB1)
LDTP04518	DNA mismatch repair protein Msh6 (MSH6)
LDTP04064	Elongation factor Ts, mitochondrial (TSFM)
LDTP03678	ER lumen protein-retaining receptor 2 (KDELR2)
LDTP06055	Eukaryotic translation initiation factor 3 subunit A (EIF3A)
LDTP07947	Eukaryotic translation initiation factor 3 subunit M (EIF3M)
LDTP05421	Eukaryotic translation initiation factor 4 gamma 1 (EIF4G1)
LDTP03762	Glycogen debranching enzyme (AGL)
LDTP02306	Guanine nucleotide-binding protein G(i) subunit alpha-3 (GNAI3)
LDTP16078	Heme-binding protein 1 (HEBP1)
LDTP04514	Heterogeneous nuclear ribonucleoprotein F (HNRNPF)
LDTP03615	Heterogeneous nuclear ribonucleoprotein H (HNRNPH1)
LDTP04714	Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2)
LDTP02750	Heterogeneous nuclear ribonucleoprotein L (HNRNPL)
LDTP05259	Heterogeneous nuclear ribonucleoprotein U (HNRNPU)
LDTP17065	Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2)
LDTP06628	Histone H2B type 2-E (H2BC21)
LDTP05004	Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16)
LDTP04367	Hsc70-interacting protein (ST13)
LDTP14272	Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)
LDTP00272	Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)
LDTP05689	Interleukin enhancer-binding factor 3 (ILF3)
LDTP02124	Keratin, type I cytoskeletal 18 (KRT18)
LDTP04094	Large proline-rich protein BAG6 (BAG6)
LDTP03354	Large ribosomal subunit protein eL13 (RPL13)
LDTP04919	Large ribosomal subunit protein eL15 (RPL15)
LDTP05509	Large ribosomal subunit protein eL18 (RPL18)
LDTP05360	Large ribosomal subunit protein eL20 (RPL18A)
LDTP05186	Large ribosomal subunit protein eL24 (RPL24)
LDTP05024	Large ribosomal subunit protein uL1 (RPL10A)
LDTP03517	Large ribosomal subunit protein uL11 (RPL12)
LDTP04106	Large ribosomal subunit protein uL18 (RPL5)
LDTP05027	Large ribosomal subunit protein uL2 (RPL8)
LDTP02961	Large ribosomal subunit protein uL22 (RPL17)
LDTP03815	Large ribosomal subunit protein uL4 (RPL4)
LDTP03658	Large ribosomal subunit protein uL6 (RPL9; RPL9P7; RPL9P8; RPL9P9)
LDTP11146	Latexin (LXN)
LDTP15500	Leucine-rich repeat transmembrane protein CCDC168 (CCDC168)
LDTP06066	Malectin (MLEC)
LDTP01432	Mitochondrial import receptor subunit TOM70 (TOMM70)
LDTP00838	Mitotic checkpoint protein BUB3 (BUB3)
LDTP11079	Myb-binding protein 1A (MYBBP1A)
LDTP05597	Neuroblast differentiation-associated protein AHNAK (AHNAK)
LDTP02164	Nucleophosmin (NPM1)
LDTP01021	Perilipin-3 (PLIN3)
LDTP06345	Periodic tryptophan protein 2 homolog (PWP2)
LDTP06167	Plastin-1 (PLS1)
LDTP06330	Plectin (PLEC)
LDTP07634	POTE ankyrin domain family member E (POTEE)
LDTP02596	Proliferating cell nuclear antigen (PCNA)
LDTP07255	Proteasome adapter and scaffold protein ECM29 (ECPAS)
LDTP10847	Protein Niban 2 (NIBAN2)
LDTP02964	Regulator of chromosome condensation (RCC1)
LDTP02816	Replication protein A 32 kDa subunit (RPA2)
LDTP01379	Ribosomal L1 domain-containing protein 1 (RSL1D1)
LDTP13044	Ribosome-binding protein 1 (RRBP1)
LDTP03775	RNA-binding protein FUS (FUS)
LDTP04395	RNA-binding protein FXR1 (FXR1)
LDTP13991	Serine-threonine kinase receptor-associated protein (STRAP)
LDTP04363	Serpin H1 (SERPINH1)
LDTP11398	Serrate RNA effector molecule homolog (SRRT)
LDTP16323	Signal recognition particle receptor subunit beta (SRPRB)
LDTP02741	Small nuclear ribonucleoprotein-associated proteins B and B' (SNRPB)
LDTP04913	Small ribosomal subunit protein eS1 (RPS3A)
LDTP04111	Small ribosomal subunit protein eS10 (RPS10)
LDTP05002	Small ribosomal subunit protein eS6 (RPS6)
LDTP04964	Small ribosomal subunit protein eS8 (RPS8)
LDTP02809	Small ribosomal subunit protein uS5 (RPS2)
LDTP01251	Splicing factor 3B subunit 1 (SF3B1)
LDTP06376	Splicing factor 3B subunit 3 (SF3B3)
LDTP03619	Stress-induced-phosphoprotein 1 (STIP1)
LDTP11643	Superkiller complex protein 8 (SKIC8)
LDTP09881	TATA-binding protein-associated factor 2N (TAF15)
LDTP07928	Transcription elongation factor SPT6 (SUPT6H)
LDTP02234	Tropomyosin beta chain (TPM2)
LDTP00759	Tumor protein D54 (TPD52L2)
LDTP05650	Twinfilin-1 (TWF1)
LDTP12025	UPF0488 protein C8orf33 (C8orf33)
LDTP01206	Vesicle-trafficking protein SEC22b (SEC22B)

1	Cell-based proteome profiling of potential dasatinib targets by use of affinity-based probes. J Am Chem Soc. 2012 Feb 15;134(6):3001-14. doi: 10.1021/ja208518u. Epub 2012 Feb 1.