Details of the Target

General Information of Target

Target ID	LDTP09365
Target Name	Cancer-associated gene 1 protein (CAGE1)
Gene Name	CAGE1
Gene ID	285782
Synonyms	CTAG3; Cancer-associated gene 1 protein; CAGE-1; Cancer/testis antigen 3; CT3
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MNKDYQKFWSSPSDPVHFEVDTSHEKVESMSESDTMNVSNLSQGVMLSHSPICMETTGTT CDLPQNEIKNFERENEYESTLCEDAYGTLDNLLNDNNIENYSTNALIQPVDTISISSLRQ FETVCKFHWVEAFDDEMTEKPEFQSQVYNYAKDNNIKQDSFKEENPMETSVSANTDQLGN EYFRQPPPRSPPLIHCSGEMLKFTEKSLAKSIAKESALNPSQPPSFLCKTAVPSKEIQNY GEIPEMSVSYEKEVTAEGVERPEIVSTWSSAGISWRSEACRENCEMPDWEQSAESLQPVQ EDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFIDVINKLKEN VEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKANYVCL QERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKREKEAQ EQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQINEV KNENAKLKQQVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNLLPDCSPCEE RLNPADIKRASQLASKMHSLLALMVGLLTCQDIINSDAEHFKESEKVSDIMLQKLKSLHL KKKTLDKEVIDCDSDEAKSIRDVPTLLGAKLDKYHSLNEELDFLVTSYEEIIECADQRLA ISHSQIAHLEERNKHLEDLIRKPREKARKPRSKSLENHPKSMTMMPALFKENRNDLD
Target Bioclass	Other
Uniprot ID	Q8TC20
Ensemble ID	ENST00000296742.11
HGNC ID	HGNC:21622

Probe(s) Labeling This Target

PAL-AfBPP Probe

Click To Hide/Show 1 Probe Related to This Target

Probe name		Structure	Binding Site(Ratio)	Interaction ID	Ref
DA-2 Probe Info			N.A.	LDD0072	[1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme

Click To Hide/Show 3 Protein(s) Interacting with This Target

Protein name	Family	Uniprot ID
Lysine-specific histone demethylase 1A (KDM1A)	Flavin monoamine oxidase family	O60341
Tumor susceptibility gene 101 protein (TSG101)	Ubiquitin-conjugating enzyme family	Q99816
Metallophosphoesterase MPPED2 (MPPED2)	UPF0046 family	Q15777

Immunoglobulin

Click To Hide/Show 1 Protein(s) Interacting with This Target

Protein name				Family	Uniprot ID
Fc receptor-like protein 5 (FCRL5)				.	Q96RD9

Other

Click To Hide/Show 7 Protein(s) Interacting with This Target

Protein name	Family	Uniprot ID
HAUS augmin-like complex subunit 1 (HAUS1)	HAUS1 family	Q96CS2
Phakinin (BFSP2)	Intermediate filament family	Q13515
MORF4 family-associated protein 1-like 1 (MRFAP1L1)	MORF4 family-associated protein family	Q96HT8
Kinetochore protein NDC80 homolog (NDC80)	NDC80/HEC1 family	O14777
Beta-taxilin (TXLNB)	Taxilin family	Q8N3L3
Tropomyosin alpha-1 chain (TPM1)	Tropomyosin family	P09493
TBC1 domain family member 23 (TBC1D23)	.	Q9NUY8

References

1	Cell-based proteome profiling of potential dasatinib targets by use of affinity-based probes. J Am Chem Soc. 2012 Feb 15;134(6):3001-14. doi: 10.1021/ja208518u. Epub 2012 Feb 1.