Details of the Target

General Information of Target

Target ID LDTP00697
Target Name Cytochrome b5 type B (CYB5B)
Gene Name CYB5B
Gene ID 80777
Synonyms
CYB5M; OMB5; Cytochrome b5 type B; Cytochrome b5 outer mitochondrial membrane isoform
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MSGSMATAEASGSDGKGQEVETSVTYYRLEEVAKRNSLKELWLVIHGRVYDVTRFLNEHP
GGEEVLLEQAGVDASESFEDVGHSSDAREMLKQYYIGDIHPSDLKPESGSKDPSKNDTCK
SCWAYWILPIIGAVLLGFLYRYYTSESKSS
Target Bioclass
Enzyme
Family
Cytochrome b5 family
Subcellular location
Mitochondrion outer membrane
Function Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.
Uniprot ID
O43169
Ensemble ID
ENST00000307892.13
HGNC ID
HGNC:24374
ChEMBL ID
CHEMBL4523134

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 34 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
HDSF-alk
 Probe Info  		1.75  LDD0197  [1]
P3
 Probe Info  		10.00  LDD0450  [2]
ILS-2
 Probe Info  		4.50  LDD0416  [3]
AZ-9
 Probe Info  		7.72  LDD0393  [4]
FBPP2
 Probe Info  		13.66  LDD0318  [5]
CHEMBL5175495
 Probe Info  		12.64  LDD0196  [6]
CY4
 Probe Info  		100.00  LDD0244  [7]
N1
 Probe Info  		100.00  LDD0242  [7]
TG42
 Probe Info  		20.82  LDD0326  [8]
TH211
 Probe Info  		Y138(20.00)  LDD0260  [9]
FBP2
 Probe Info  		19.34  LDD0317  [5]
IBr-1b
 Probe Info  		15.09  LDD0306  [10]
YN-1
 Probe Info  		100.00  LDD0444  [11]
YN-4
 Probe Info  		100.00  LDD0445  [11]
STPyne
 Probe Info  		K39(7.69)  LDD0277  [12]
IPM
 Probe Info  		N.A.  LDD0241  [13]
m-APA
 Probe Info  		12.13  LDD0403  [14]
Alkylaryl probe 2
 Probe Info  		3.00  LDD0392  [15]
P11
 Probe Info  		2.63  LDD0210  [16]
Curcusone 37
 Probe Info  		2.56  LDD0188  [17]
Johansson_61
 Probe Info  		_(10.95)  LDD1485  [18]
YY4-yne
 Probe Info  		2.86  LDD0400  [19]
DA-P3
 Probe Info  		8.79  LDD0179  [20]
HPAP
 Probe Info  		3.16  LDD0062  [21]
IA-alkyne
 Probe Info  		14.97  LDD0432  [22]
DBIA
 Probe Info  		C115(1.24)  LDD0531  [23]
5E-2FA
 Probe Info  		N.A.  LDD2235  [24]
JW-RF-010
 Probe Info  		N.A.  LDD0026  [25]
TFBX
 Probe Info  		N.A.  LDD0027  [25]
WYneO
 Probe Info  		N.A.  LDD0022  [26]
ENE
 Probe Info  		N.A.  LDD0006  [26]
Acrolein
 Probe Info  		N.A.  LDD0217  [27]
W1
 Probe Info  		C115(0.00); E36(0.00)  LDD0236  [13]
AOyne
 Probe Info  		7.60  LDD0443  [28]
PAL-AfBPP Probe
Click To Hide/Show 202 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DR-1
 Probe Info  		7.48  LDD0398  [29]
C001
 Probe Info  		5.94  LDD1711  [30]
C004
 Probe Info  		19.43  LDD1714  [30]
C007
 Probe Info  		13.83  LDD1716  [30]
C010
 Probe Info  		7.84  LDD1719  [30]
C011
 Probe Info  		5.17  LDD1720  [30]
C017
 Probe Info  		6.15  LDD1725  [30]
C022
 Probe Info  		31.34  LDD1728  [30]
C026
 Probe Info  		9.78  LDD1732  [30]
C027
 Probe Info  		23.92  LDD1733  [30]
C039
 Probe Info  		5.21  LDD1739  [30]
C040
 Probe Info  		36.00  LDD1740  [30]
C041
 Probe Info  		9.25  LDD1741  [30]
C044
 Probe Info  		5.46  LDD1743  [30]
C049
 Probe Info  		29.86  LDD1747  [30]
C051
 Probe Info  		5.74  LDD1749  [30]
C053
 Probe Info  		17.03  LDD1751  [30]
C055
 Probe Info  		50.91  LDD1752  [30]
C056
 Probe Info  		71.51  LDD1753  [30]
C060
 Probe Info  		5.13  LDD1757  [30]
C063
 Probe Info  		36.25  LDD1760  [30]
C064
 Probe Info  		9.32  LDD1761  [30]
C067
 Probe Info  		13.00  LDD1763  [30]
C070
 Probe Info  		30.06  LDD1766  [30]
C071
 Probe Info  		12.21  LDD1767  [30]
C072
 Probe Info  		28.84  LDD1768  [30]
C082
 Probe Info  		17.27  LDD1774  [30]
C085
 Probe Info  		6.63  LDD1777  [30]
C087
 Probe Info  		11.63  LDD1779  [30]
C091
 Probe Info  		64.89  LDD1782  [30]
C092
 Probe Info  		99.73  LDD1783  [30]
C094
 Probe Info  		89.88  LDD1785  [30]
C095
 Probe Info  		25.81  LDD1786  [30]
C099
 Probe Info  		6.50  LDD1788  [30]
C100
 Probe Info  		27.28  LDD1789  [30]
C102
 Probe Info  		5.50  LDD1790  [30]
C106
 Probe Info  		99.73  LDD1793  [30]
C107
 Probe Info  		30.70  LDD1794  [30]
C108
 Probe Info  		30.70  LDD1795  [30]
C112
 Probe Info  		99.73  LDD1799  [30]
C129
 Probe Info  		12.38  LDD1811  [30]
C130
 Probe Info  		20.25  LDD1812  [30]
C134
 Probe Info  		99.73  LDD1816  [30]
C135
 Probe Info  		39.67  LDD1817  [30]
C139
 Probe Info  		42.22  LDD1821  [30]
C140
 Probe Info  		13.64  LDD1822  [30]
C141
 Probe Info  		30.48  LDD1823  [30]
C143
 Probe Info  		73.01  LDD1825  [30]
C147
 Probe Info  		10.85  LDD1829  [30]
C153
 Probe Info  		66.72  LDD1834  [30]
C156
 Probe Info  		10.41  LDD1836  [30]
C158
 Probe Info  		23.92  LDD1838  [30]
C159
 Probe Info  		74.54  LDD1839  [30]
C160
 Probe Info  		56.10  LDD1840  [30]
C161
 Probe Info  		99.73  LDD1841  [30]
C163
 Probe Info  		21.26  LDD1843  [30]
C165
 Probe Info  		32.90  LDD1845  [30]
C166
 Probe Info  		14.93  LDD1846  [30]
C169
 Probe Info  		99.73  LDD1849  [30]
C170
 Probe Info  		31.34  LDD1850  [30]
C172
 Probe Info  		17.75  LDD1852  [30]
C173
 Probe Info  		17.75  LDD1853  [30]
C174
 Probe Info  		13.55  LDD1854  [30]
C177
 Probe Info  		18.90  LDD1856  [30]
C178
 Probe Info  		78.79  LDD1857  [30]
C183
 Probe Info  		8.34  LDD1861  [30]
C185
 Probe Info  		5.39  LDD1863  [30]
C186
 Probe Info  		27.47  LDD1864  [30]
C187
 Probe Info  		59.30  LDD1865  [30]
C191
 Probe Info  		22.78  LDD1868  [30]
C193
 Probe Info  		11.08  LDD1869  [30]
C194
 Probe Info  		19.16  LDD1870  [30]
C196
 Probe Info  		36.25  LDD1872  [30]
C197
 Probe Info  		10.48  LDD1873  [30]
C198
 Probe Info  		36.00  LDD1874  [30]
C199
 Probe Info  		6.82  LDD1875  [30]
C201
 Probe Info  		99.73  LDD1877  [30]
C204
 Probe Info  		6.87  LDD1879  [30]
C206
 Probe Info  		78.79  LDD1881  [30]
C207
 Probe Info  		67.18  LDD1882  [30]
C210
 Probe Info  		99.73  LDD1884  [30]
C211
 Probe Info  		10.06  LDD1885  [30]
C213
 Probe Info  		23.10  LDD1887  [30]
C216
 Probe Info  		5.82  LDD1890  [30]
C218
 Probe Info  		99.73  LDD1892  [30]
C219
 Probe Info  		23.10  LDD1893  [30]
C220
 Probe Info  		99.73  LDD1894  [30]
C225
 Probe Info  		24.25  LDD1898  [30]
C226
 Probe Info  		24.93  LDD1899  [30]
C228
 Probe Info  		99.73  LDD1901  [30]
C229
 Probe Info  		8.94  LDD1902  [30]
C231
 Probe Info  		76.64  LDD1904  [30]
C232
 Probe Info  		56.10  LDD1905  [30]
C233
 Probe Info  		16.11  LDD1906  [30]
C234
 Probe Info  		9.51  LDD1907  [30]
C235
 Probe Info  		60.97  LDD1908  [30]
C238
 Probe Info  		99.73  LDD1911  [30]
C240
 Probe Info  		30.70  LDD1913  [30]
C243
 Probe Info  		64.89  LDD1916  [30]
C244
 Probe Info  		26.17  LDD1917  [30]
C245
 Probe Info  		9.32  LDD1918  [30]
C246
 Probe Info  		99.73  LDD1919  [30]
C249
 Probe Info  		25.81  LDD1922  [30]
C251
 Probe Info  		64.00  LDD1924  [30]
C252
 Probe Info  		41.93  LDD1925  [30]
C258
 Probe Info  		9.00  LDD1931  [30]
C260
 Probe Info  		5.54  LDD1932  [30]
C264
 Probe Info  		52.35  LDD1935  [30]
C265
 Probe Info  		35.02  LDD1936  [30]
C266
 Probe Info  		8.75  LDD1937  [30]
C270
 Probe Info  		10.85  LDD1940  [30]
C271
 Probe Info  		7.62  LDD1941  [30]
C273
 Probe Info  		12.55  LDD1943  [30]
C275
 Probe Info  		7.21  LDD1945  [30]
C277
 Probe Info  		21.41  LDD1947  [30]
C278
 Probe Info  		99.73  LDD1948  [30]
C282
 Probe Info  		28.84  LDD1952  [30]
C285
 Probe Info  		99.73  LDD1955  [30]
C286
 Probe Info  		5.13  LDD1956  [30]
C287
 Probe Info  		44.94  LDD1957  [30]
C288
 Probe Info  		23.26  LDD1958  [30]
C289
 Probe Info  		99.73  LDD1959  [30]
C290
 Probe Info  		11.08  LDD1960  [30]
C293
 Probe Info  		99.73  LDD1963  [30]
C296
 Probe Info  		44.02  LDD1966  [30]
C299
 Probe Info  		23.10  LDD1968  [30]
C304
 Probe Info  		6.02  LDD1973  [30]
C305
 Probe Info  		21.71  LDD1974  [30]
C307
 Probe Info  		9.71  LDD1975  [30]
C310
 Probe Info  		45.25  LDD1977  [30]
C311
 Probe Info  		8.34  LDD1978  [30]
C313
 Probe Info  		18.00  LDD1980  [30]
C314
 Probe Info  		15.56  LDD1981  [30]
C317
 Probe Info  		6.96  LDD1983  [30]
C320
 Probe Info  		5.43  LDD1986  [30]
C322
 Probe Info  		22.32  LDD1988  [30]
C326
 Probe Info  		13.18  LDD1990  [30]
C327
 Probe Info  		5.66  LDD1991  [30]
C333
 Probe Info  		5.28  LDD1996  [30]
C337
 Probe Info  		6.96  LDD2000  [30]
C338
 Probe Info  		17.88  LDD2001  [30]
C339
 Probe Info  		29.24  LDD2002  [30]
C342
 Probe Info  		5.70  LDD2004  [30]
C343
 Probe Info  		60.55  LDD2005  [30]
C346
 Probe Info  		11.00  LDD2007  [30]
C348
 Probe Info  		57.28  LDD2009  [30]
C349
 Probe Info  		99.73  LDD2010  [30]
C350
 Probe Info  		99.73  LDD2011  [30]
C353
 Probe Info  		20.11  LDD2014  [30]
C354
 Probe Info  		16.22  LDD2015  [30]
C355
 Probe Info  		64.45  LDD2016  [30]
C356
 Probe Info  		68.12  LDD2017  [30]
C357
 Probe Info  		27.86  LDD2018  [30]
C361
 Probe Info  		25.81  LDD2022  [30]
C362
 Probe Info  		99.73  LDD2023  [30]
C363
 Probe Info  		67.18  LDD2024  [30]
C364
 Probe Info  		79.89  LDD2025  [30]
C366
 Probe Info  		54.19  LDD2027  [30]
C367
 Probe Info  		21.11  LDD2028  [30]
C373
 Probe Info  		23.10  LDD2033  [30]
C376
 Probe Info  		18.38  LDD2036  [30]
C378
 Probe Info  		11.08  LDD2037  [30]
C380
 Probe Info  		13.45  LDD2039  [30]
C382
 Probe Info  		31.12  LDD2041  [30]
C383
 Probe Info  		19.03  LDD2042  [30]
C384
 Probe Info  		5.54  LDD2043  [30]
C386
 Probe Info  		16.11  LDD2045  [30]
C388
 Probe Info  		99.73  LDD2047  [30]
C390
 Probe Info  		99.73  LDD2049  [30]
C391
 Probe Info  		19.84  LDD2050  [30]
C396
 Probe Info  		6.11  LDD2055  [30]
C397
 Probe Info  		10.78  LDD2056  [30]
C399
 Probe Info  		22.47  LDD2058  [30]
C403
 Probe Info  		79.89  LDD2061  [30]
C407
 Probe Info  		36.00  LDD2064  [30]
C409
 Probe Info  		5.54  LDD2066  [30]
C413
 Probe Info  		91.77  LDD2069  [30]
C419
 Probe Info  		65.80  LDD2074  [30]
C420
 Probe Info  		27.10  LDD2075  [30]
C422
 Probe Info  		15.67  LDD2077  [30]
C423
 Probe Info  		99.73  LDD2078  [30]
C424
 Probe Info  		29.45  LDD2079  [30]
C426
 Probe Info  		49.87  LDD2081  [30]
C429
 Probe Info  		54.19  LDD2084  [30]
C430
 Probe Info  		5.06  LDD2085  [30]
C431
 Probe Info  		99.73  LDD2086  [30]
C433
 Probe Info  		8.40  LDD2088  [30]
FFF probe11
 Probe Info  		20.00  LDD0471  [31]
FFF probe13
 Probe Info  		20.00  LDD0475  [31]
FFF probe14
 Probe Info  		20.00  LDD0477  [31]
FFF probe15
 Probe Info  		8.04  LDD0478  [31]
FFF probe2
 Probe Info  		20.00  LDD0463  [31]
FFF probe3
 Probe Info  		20.00  LDD0464  [31]
FFF probe4
 Probe Info  		20.00  LDD0466  [31]
FFF probe9
 Probe Info  		20.00  LDD0470  [31]
JN0003
 Probe Info  		20.00  LDD0469  [31]
STS-1
 Probe Info  		N.A.  LDD0136  [32]
A-DA
 Probe Info  		2.09  LDD0143  [33]
Alk-rapa
 Probe Info  		6.16  LDD0213  [34]
Staurosporine capture compound
 Probe Info  		N.A.  LDD0083  [35]
DA-2
 Probe Info  		N.A.  LDD0072  [36]
OEA-DA
 Probe Info  		4.37  LDD0046  [37]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HCT 116 C115(1.24)  LDD0531  [23]
 LDCM0216  AC100 HCT 116 C115(1.58)  LDD0533  [23]
 LDCM0217  AC101 HCT 116 C115(1.51)  LDD0534  [23]
 LDCM0218  AC102 HCT 116 C115(1.57)  LDD0535  [23]
 LDCM0219  AC103 HCT 116 C115(1.70)  LDD0536  [23]
 LDCM0220  AC104 HCT 116 C115(1.30)  LDD0537  [23]
 LDCM0221  AC105 HCT 116 C115(1.66)  LDD0538  [23]
 LDCM0222  AC106 HCT 116 C115(1.77)  LDD0539  [23]
 LDCM0223  AC107 HCT 116 C115(2.00)  LDD0540  [23]
 LDCM0224  AC108 HCT 116 C115(1.72)  LDD0541  [23]
 LDCM0225  AC109 HCT 116 C115(1.33)  LDD0542  [23]
 LDCM0227  AC110 HCT 116 C115(1.88)  LDD0544  [23]
 LDCM0228  AC111 HCT 116 C115(1.64)  LDD0545  [23]
 LDCM0229  AC112 HCT 116 C115(1.54)  LDD0546  [23]
 LDCM0230  AC113 HCT 116 C115(0.99)  LDD0547  [23]
 LDCM0231  AC114 HCT 116 C115(1.32)  LDD0548  [23]
 LDCM0232  AC115 HCT 116 C115(1.57)  LDD0549  [23]
 LDCM0233  AC116 HCT 116 C115(1.69)  LDD0550  [23]
 LDCM0234  AC117 HCT 116 C115(1.11)  LDD0551  [23]
 LDCM0235  AC118 HCT 116 C115(1.16)  LDD0552  [23]
 LDCM0236  AC119 HCT 116 C115(1.29)  LDD0553  [23]
 LDCM0238  AC120 HCT 116 C115(2.37)  LDD0555  [23]
 LDCM0239  AC121 HCT 116 C115(0.98)  LDD0556  [23]
 LDCM0240  AC122 HCT 116 C115(1.25)  LDD0557  [23]
 LDCM0241  AC123 HCT 116 C115(1.07)  LDD0558  [23]
 LDCM0242  AC124 HCT 116 C115(1.17)  LDD0559  [23]
 LDCM0243  AC125 HCT 116 C115(1.19)  LDD0560  [23]
 LDCM0244  AC126 HCT 116 C115(1.32)  LDD0561  [23]
 LDCM0245  AC127 HCT 116 C115(1.48)  LDD0562  [23]
 LDCM0246  AC128 HCT 116 C115(0.80)  LDD0563  [23]
 LDCM0247  AC129 HCT 116 C115(1.14)  LDD0564  [23]
 LDCM0249  AC130 HCT 116 C115(0.82)  LDD0566  [23]
 LDCM0250  AC131 HCT 116 C115(0.89)  LDD0567  [23]
 LDCM0251  AC132 HCT 116 C115(0.98)  LDD0568  [23]
 LDCM0252  AC133 HCT 116 C115(0.93)  LDD0569  [23]
 LDCM0253  AC134 HCT 116 C115(0.91)  LDD0570  [23]
 LDCM0254  AC135 HCT 116 C115(0.92)  LDD0571  [23]
 LDCM0255  AC136 HCT 116 C115(0.96)  LDD0572  [23]
 LDCM0256  AC137 HCT 116 C115(1.06)  LDD0573  [23]
 LDCM0257  AC138 HCT 116 C115(1.08)  LDD0574  [23]
 LDCM0258  AC139 HCT 116 C115(0.87)  LDD0575  [23]
 LDCM0260  AC140 HCT 116 C115(0.83)  LDD0577  [23]
 LDCM0261  AC141 HCT 116 C115(0.93)  LDD0578  [23]
 LDCM0262  AC142 HCT 116 C115(1.41)  LDD0579  [23]
 LDCM0263  AC143 HCT 116 C115(1.36)  LDD0580  [23]
 LDCM0264  AC144 HCT 116 C115(1.81)  LDD0581  [23]
 LDCM0265  AC145 HCT 116 C115(1.59)  LDD0582  [23]
 LDCM0266  AC146 HCT 116 C115(1.77)  LDD0583  [23]
 LDCM0267  AC147 HCT 116 C115(2.07)  LDD0584  [23]
 LDCM0268  AC148 HCT 116 C115(3.27)  LDD0585  [23]
 LDCM0269  AC149 HCT 116 C115(2.21)  LDD0586  [23]
 LDCM0271  AC150 HCT 116 C115(1.38)  LDD0588  [23]
 LDCM0272  AC151 HCT 116 C115(1.43)  LDD0589  [23]
 LDCM0273  AC152 HCT 116 C115(2.27)  LDD0590  [23]
 LDCM0274  AC153 HCT 116 C115(3.11)  LDD0591  [23]
 LDCM0621  AC154 HCT 116 C115(1.86)  LDD2158  [23]
 LDCM0622  AC155 HCT 116 C115(2.25)  LDD2159  [23]
 LDCM0623  AC156 HCT 116 C115(1.54)  LDD2160  [23]
 LDCM0624  AC157 HCT 116 C115(1.39)  LDD2161  [23]
 LDCM0279  AC2 HCT 116 C115(1.03)  LDD0596  [23]
 LDCM0285  AC25 HCT 116 C115(1.12)  LDD0602  [23]
 LDCM0286  AC26 HCT 116 C115(1.24)  LDD0603  [23]
 LDCM0287  AC27 HCT 116 C115(1.61)  LDD0604  [23]
 LDCM0288  AC28 HCT 116 C115(1.65)  LDD0605  [23]
 LDCM0289  AC29 HCT 116 C115(1.63)  LDD0606  [23]
 LDCM0290  AC3 HCT 116 C115(1.54)  LDD0607  [23]
 LDCM0291  AC30 HCT 116 C115(1.94)  LDD0608  [23]
 LDCM0292  AC31 HCT 116 C115(1.33)  LDD0609  [23]
 LDCM0293  AC32 HCT 116 C115(1.86)  LDD0610  [23]
 LDCM0294  AC33 HCT 116 C115(0.93)  LDD0611  [23]
 LDCM0295  AC34 HCT 116 C115(0.96)  LDD0612  [23]
 LDCM0296  AC35 HCT 116 C115(1.29)  LDD0613  [23]
 LDCM0297  AC36 HCT 116 C115(1.27)  LDD0614  [23]
 LDCM0298  AC37 HCT 116 C115(1.14)  LDD0615  [23]
 LDCM0299  AC38 HCT 116 C115(1.34)  LDD0616  [23]
 LDCM0300  AC39 HCT 116 C115(1.38)  LDD0617  [23]
 LDCM0301  AC4 HCT 116 C115(1.57)  LDD0618  [23]
 LDCM0302  AC40 HCT 116 C115(1.06)  LDD0619  [23]
 LDCM0303  AC41 HCT 116 C115(1.24)  LDD0620  [23]
 LDCM0304  AC42 HCT 116 C115(1.18)  LDD0621  [23]
 LDCM0305  AC43 HCT 116 C115(1.22)  LDD0622  [23]
 LDCM0306  AC44 HCT 116 C115(1.21)  LDD0623  [23]
 LDCM0307  AC45 HCT 116 C115(1.22)  LDD0624  [23]
 LDCM0308  AC46 HCT 116 C115(0.77)  LDD0625  [23]
 LDCM0309  AC47 HCT 116 C115(0.78)  LDD0626  [23]
 LDCM0310  AC48 HCT 116 C115(0.83)  LDD0627  [23]
 LDCM0311  AC49 HCT 116 C115(2.53)  LDD0628  [23]
 LDCM0312  AC5 HCT 116 C115(1.54)  LDD0629  [23]
 LDCM0313  AC50 HCT 116 C115(1.15)  LDD0630  [23]
 LDCM0314  AC51 HCT 116 C115(0.59)  LDD0631  [23]
 LDCM0315  AC52 HCT 116 C115(0.83)  LDD0632  [23]
 LDCM0316  AC53 HCT 116 C115(1.04)  LDD0633  [23]
 LDCM0317  AC54 HCT 116 C115(1.64)  LDD0634  [23]
 LDCM0318  AC55 HCT 116 C115(1.36)  LDD0635  [23]
 LDCM0319  AC56 HCT 116 C115(1.73)  LDD0636  [23]
 LDCM0332  AC68 HCT 116 C115(0.88)  LDD0649  [23]
 LDCM0333  AC69 HCT 116 C115(0.87)  LDD0650  [23]
 LDCM0335  AC70 HCT 116 C115(1.46)  LDD0652  [23]
 LDCM0336  AC71 HCT 116 C115(0.90)  LDD0653  [23]
 LDCM0337  AC72 HCT 116 C115(1.61)  LDD0654  [23]
 LDCM0338  AC73 HCT 116 C115(1.64)  LDD0655  [23]
 LDCM0339  AC74 HCT 116 C115(1.41)  LDD0656  [23]
 LDCM0340  AC75 HCT 116 C115(1.21)  LDD0657  [23]
 LDCM0341  AC76 HCT 116 C115(1.13)  LDD0658  [23]
 LDCM0342  AC77 HCT 116 C115(0.99)  LDD0659  [23]
 LDCM0343  AC78 HCT 116 C115(1.08)  LDD0660  [23]
 LDCM0344  AC79 HCT 116 C115(1.30)  LDD0661  [23]
 LDCM0346  AC80 HCT 116 C115(1.24)  LDD0663  [23]
 LDCM0347  AC81 HCT 116 C115(0.88)  LDD0664  [23]
 LDCM0348  AC82 HCT 116 C115(1.14)  LDD0665  [23]
 LDCM0349  AC83 HCT 116 C115(1.41)  LDD0666  [23]
 LDCM0350  AC84 HCT 116 C115(1.35)  LDD0667  [23]
 LDCM0351  AC85 HCT 116 C115(1.18)  LDD0668  [23]
 LDCM0352  AC86 HCT 116 C115(1.93)  LDD0669  [23]
 LDCM0353  AC87 HCT 116 C115(1.20)  LDD0670  [23]
 LDCM0354  AC88 HCT 116 C115(1.65)  LDD0671  [23]
 LDCM0355  AC89 HCT 116 C115(1.86)  LDD0672  [23]
 LDCM0357  AC90 HCT 116 C115(1.26)  LDD0674  [23]
 LDCM0358  AC91 HCT 116 C115(0.93)  LDD0675  [23]
 LDCM0359  AC92 HCT 116 C115(1.11)  LDD0676  [23]
 LDCM0360  AC93 HCT 116 C115(0.89)  LDD0677  [23]
 LDCM0361  AC94 HCT 116 C115(0.92)  LDD0678  [23]
 LDCM0362  AC95 HCT 116 C115(1.66)  LDD0679  [23]
 LDCM0363  AC96 HCT 116 C115(0.75)  LDD0680  [23]
 LDCM0364  AC97 HCT 116 C115(0.79)  LDD0681  [23]
 LDCM0365  AC98 HCT 116 C115(2.28)  LDD0682  [23]
 LDCM0366  AC99 HCT 116 C115(1.89)  LDD0683  [23]
 LDCM0156  Aniline NCI-H1299 12.13  LDD0403  [14]
 LDCM0083  Avasimibe A-549 2.09  LDD0143  [33]
 LDCM0151  AZ-11 HeLa 10.00  LDD2154  [4]
 LDCM0199  BPK-21 T cell C115(7.49)  LDD0530  [38]
 LDCM0200  BPK-25 T cell C115(7.99)  LDD0529  [38]
 LDCM0089  C30 HEK-293T 2.63  LDD0210  [16]
 LDCM0088  C45 HEK-293T 1.56  LDD0211  [16]
 LDCM0108  Chloroacetamide HeLa N.A.  LDD0222  [27]
 LDCM0367  CL1 HCT 116 C115(1.02)  LDD0684  [23]
 LDCM0368  CL10 HCT 116 C115(1.32)  LDD0685  [23]
 LDCM0369  CL100 HCT 116 C115(1.27)  LDD0686  [23]
 LDCM0379  CL11 HCT 116 C115(1.02)  LDD0696  [23]
 LDCM0382  CL112 HCT 116 C115(1.14)  LDD0699  [23]
 LDCM0383  CL113 HCT 116 C115(1.30)  LDD0700  [23]
 LDCM0384  CL114 HCT 116 C115(2.55)  LDD0701  [23]
 LDCM0385  CL115 HCT 116 C115(1.30)  LDD0702  [23]
 LDCM0386  CL116 HCT 116 C115(1.50)  LDD0703  [23]
 LDCM0387  CL117 HCT 116 C115(1.23)  LDD0704  [23]
 LDCM0388  CL118 HCT 116 C115(1.36)  LDD0705  [23]
 LDCM0389  CL119 HCT 116 C115(1.06)  LDD0706  [23]
 LDCM0390  CL12 HCT 116 C115(0.87)  LDD0707  [23]
 LDCM0391  CL120 HCT 116 C115(1.34)  LDD0708  [23]
 LDCM0392  CL121 HCT 116 C115(0.71)  LDD0709  [23]
 LDCM0393  CL122 HCT 116 C115(0.87)  LDD0710  [23]
 LDCM0394  CL123 HCT 116 C115(2.38)  LDD0711  [23]
 LDCM0395  CL124 HCT 116 C115(1.31)  LDD0712  [23]
 LDCM0400  CL13 HCT 116 C115(0.91)  LDD0717  [23]
 LDCM0401  CL14 HCT 116 C115(0.85)  LDD0718  [23]
 LDCM0402  CL15 HCT 116 C115(0.93)  LDD0719  [23]
 LDCM0404  CL17 HCT 116 C115(2.32)  LDD0721  [23]
 LDCM0405  CL18 HCT 116 C115(1.01)  LDD0722  [23]
 LDCM0406  CL19 HCT 116 C115(1.03)  LDD0723  [23]
 LDCM0407  CL2 HCT 116 C115(0.67)  LDD0724  [23]
 LDCM0408  CL20 HCT 116 C115(0.85)  LDD0725  [23]
 LDCM0409  CL21 HCT 116 C115(1.89)  LDD0726  [23]
 LDCM0410  CL22 HCT 116 C115(0.52)  LDD0727  [23]
 LDCM0411  CL23 HCT 116 C115(0.81)  LDD0728  [23]
 LDCM0412  CL24 HCT 116 C115(0.66)  LDD0729  [23]
 LDCM0413  CL25 HCT 116 C115(1.20)  LDD0730  [23]
 LDCM0414  CL26 HCT 116 C115(1.08)  LDD0731  [23]
 LDCM0415  CL27 HCT 116 C115(0.83)  LDD0732  [23]
 LDCM0416  CL28 HCT 116 C115(1.19)  LDD0733  [23]
 LDCM0417  CL29 HCT 116 C115(0.30)  LDD0734  [23]
 LDCM0418  CL3 HCT 116 C115(0.74)  LDD0735  [23]
 LDCM0419  CL30 HCT 116 C115(0.10)  LDD0736  [23]
 LDCM0420  CL31 HCT 116 C115(1.17)  LDD0737  [23]
 LDCM0421  CL32 HCT 116 C115(0.90)  LDD0738  [23]
 LDCM0422  CL33 HCT 116 C115(1.07)  LDD0739  [23]
 LDCM0423  CL34 HCT 116 C115(0.97)  LDD0740  [23]
 LDCM0424  CL35 HCT 116 C115(1.22)  LDD0741  [23]
 LDCM0425  CL36 HCT 116 C115(2.60)  LDD0742  [23]
 LDCM0426  CL37 HCT 116 C115(1.31)  LDD0743  [23]
 LDCM0428  CL39 HCT 116 C115(1.34)  LDD0745  [23]
 LDCM0429  CL4 HCT 116 C115(0.43)  LDD0746  [23]
 LDCM0430  CL40 HCT 116 C115(4.45)  LDD0747  [23]
 LDCM0431  CL41 HCT 116 C115(1.09)  LDD0748  [23]
 LDCM0432  CL42 HCT 116 C115(2.39)  LDD0749  [23]
 LDCM0433  CL43 HCT 116 C115(1.22)  LDD0750  [23]
 LDCM0434  CL44 HCT 116 C115(1.21)  LDD0751  [23]
 LDCM0435  CL45 HCT 116 C115(4.97)  LDD0752  [23]
 LDCM0436  CL46 HCT 116 C115(1.22)  LDD0753  [23]
 LDCM0437  CL47 HCT 116 C115(1.40)  LDD0754  [23]
 LDCM0438  CL48 HCT 116 C115(1.49)  LDD0755  [23]
 LDCM0439  CL49 HCT 116 C115(1.36)  LDD0756  [23]
 LDCM0440  CL5 HCT 116 C115(0.79)  LDD0757  [23]
 LDCM0441  CL50 HCT 116 C115(1.48)  LDD0758  [23]
 LDCM0442  CL51 HCT 116 C115(1.49)  LDD0759  [23]
 LDCM0443  CL52 HCT 116 C115(1.47)  LDD0760  [23]
 LDCM0444  CL53 HCT 116 C115(6.34)  LDD0761  [23]
 LDCM0445  CL54 HCT 116 C115(2.12)  LDD0762  [23]
 LDCM0446  CL55 HCT 116 C115(1.65)  LDD0763  [23]
 LDCM0447  CL56 HCT 116 C115(1.35)  LDD0764  [23]
 LDCM0448  CL57 HCT 116 C115(1.45)  LDD0765  [23]
 LDCM0449  CL58 HCT 116 C115(1.32)  LDD0766  [23]
 LDCM0450  CL59 HCT 116 C115(1.20)  LDD0767  [23]
 LDCM0451  CL6 HCT 116 C115(1.10)  LDD0768  [23]
 LDCM0452  CL60 HCT 116 C115(1.43)  LDD0769  [23]
 LDCM0453  CL61 HCT 116 C115(0.86)  LDD0770  [23]
 LDCM0454  CL62 HCT 116 C115(1.07)  LDD0771  [23]
 LDCM0455  CL63 HCT 116 C115(1.08)  LDD0772  [23]
 LDCM0456  CL64 HCT 116 C115(1.29)  LDD0773  [23]
 LDCM0457  CL65 HCT 116 C115(1.17)  LDD0774  [23]
 LDCM0458  CL66 HCT 116 C115(1.52)  LDD0775  [23]
 LDCM0459  CL67 HCT 116 C115(1.43)  LDD0776  [23]
 LDCM0460  CL68 HCT 116 C115(0.80)  LDD0777  [23]
 LDCM0461  CL69 HCT 116 C115(0.74)  LDD0778  [23]
 LDCM0462  CL7 HCT 116 C115(0.96)  LDD0779  [23]
 LDCM0463  CL70 HCT 116 C115(0.85)  LDD0780  [23]
 LDCM0464  CL71 HCT 116 C115(1.30)  LDD0781  [23]
 LDCM0465  CL72 HCT 116 C115(1.17)  LDD0782  [23]
 LDCM0466  CL73 HCT 116 C115(1.15)  LDD0783  [23]
 LDCM0467  CL74 HCT 116 C115(1.21)  LDD0784  [23]
 LDCM0469  CL76 HCT 116 C115(0.83)  LDD0786  [23]
 LDCM0470  CL77 HCT 116 C115(1.26)  LDD0787  [23]
 LDCM0471  CL78 HCT 116 C115(0.78)  LDD0788  [23]
 LDCM0472  CL79 HCT 116 C115(0.77)  LDD0789  [23]
 LDCM0473  CL8 HCT 116 C115(2.66)  LDD0790  [23]
 LDCM0474  CL80 HCT 116 C115(0.74)  LDD0791  [23]
 LDCM0475  CL81 HCT 116 C115(0.80)  LDD0792  [23]
 LDCM0476  CL82 HCT 116 C115(0.67)  LDD0793  [23]
 LDCM0477  CL83 HCT 116 C115(1.22)  LDD0794  [23]
 LDCM0478  CL84 HCT 116 C115(0.99)  LDD0795  [23]
 LDCM0479  CL85 HCT 116 C115(0.86)  LDD0796  [23]
 LDCM0480  CL86 HCT 116 C115(0.79)  LDD0797  [23]
 LDCM0481  CL87 HCT 116 C115(0.72)  LDD0798  [23]
 LDCM0482  CL88 HCT 116 C115(0.74)  LDD0799  [23]
 LDCM0483  CL89 HCT 116 C115(0.72)  LDD0800  [23]
 LDCM0484  CL9 HCT 116 C115(0.99)  LDD0801  [23]
 LDCM0485  CL90 HCT 116 C115(1.46)  LDD0802  [23]
 LDCM0486  CL91 HCT 116 C115(1.18)  LDD0803  [23]
 LDCM0487  CL92 HCT 116 C115(1.60)  LDD0804  [23]
 LDCM0488  CL93 HCT 116 C115(0.78)  LDD0805  [23]
 LDCM0489  CL94 HCT 116 C115(0.72)  LDD0806  [23]
 LDCM0490  CL95 HCT 116 C115(0.99)  LDD0807  [23]
 LDCM0491  CL96 HCT 116 C115(0.77)  LDD0808  [23]
 LDCM0492  CL97 HCT 116 C115(0.91)  LDD0809  [23]
 LDCM0493  CL98 HCT 116 C115(1.68)  LDD0810  [23]
 LDCM0494  CL99 HCT 116 C115(1.44)  LDD0811  [23]
 LDCM0189  Compound 16 HEK-293T 17.54  LDD0492  [31]
 LDCM0185  Compound 17 HEK-293T 20.63  LDD0504  [31]
 LDCM0184  Compound 20 HEK-293T 13.04  LDD0503  [31]
 LDCM0191  Compound 21 HEK-293T 8.33  LDD0493  [31]
 LDCM0190  Compound 34 HEK-293T 18.35  LDD0497  [31]
 LDCM0192  Compound 35 HEK-293T 10.99  LDD0491  [31]
 LDCM0193  Compound 36 HEK-293T 4.47  LDD0494  [31]
 LDCM0194  Compound 37 HEK-293T 7.07  LDD0498  [31]
 LDCM0195  Compound 38 HEK-293T 12.90  LDD0499  [31]
 LDCM0196  Compound 39 HEK-293T 9.80  LDD0496  [31]
 LDCM0197  Compound 40 HEK-293T 13.16  LDD0495  [31]
 LDCM0033  Curcusone1d MCF-7 2.56  LDD0188  [17]
 LDCM0027  Dopamine HEK-293T 8.79  LDD0179  [20]
 LDCM0202  EV-93 T cell C115(20.00)  LDD0527  [38]
 LDCM0203  EV-96 T cell C115(8.09)  LDD0523  [38]
 LDCM0204  EV-97 T cell C115(20.00)  LDD0525  [38]
 LDCM0625  F8 Ramos C119(1.05)  LDD2187  [39]
 LDCM0573  Fragment11 Ramos C119(1.90)  LDD2190  [39]
 LDCM0576  Fragment14 Ramos C119(6.23)  LDD2193  [39]
 LDCM0580  Fragment21 Ramos C119(4.48)  LDD2195  [39]
 LDCM0582  Fragment23 Ramos C119(1.49)  LDD2196  [39]
 LDCM0578  Fragment27 Ramos C119(1.42)  LDD2197  [39]
 LDCM0586  Fragment28 Ramos C119(1.20)  LDD2198  [39]
 LDCM0589  Fragment31 Ramos C119(1.39)  LDD2200  [39]
 LDCM0468  Fragment33 HCT 116 C115(0.87)  LDD0785  [23]
 LDCM0596  Fragment38 Ramos C119(6.41)  LDD2203  [39]
 LDCM0427  Fragment51 HCT 116 C115(4.10)  LDD0744  [23]
 LDCM0614  Fragment56 Ramos C119(1.47)  LDD2205  [39]
 LDCM0616  Fragment61 Jurkat _(17.94)  LDD1489  [18]
 LDCM0615  Fragment63-R Jurkat _(14.04)  LDD1487  [18]
 LDCM0617  Fragment63-S Jurkat _(20.00)  LDD1490  [18]
 LDCM0569  Fragment7 Jurkat _(10.95)  LDD1485  [18]
 LDCM0107  IAA HeLa H83(0.00); H46(0.00)  LDD0221  [27]
 LDCM0022  KB02 T cell C115(20.00)  LDD1707  [38]
 LDCM0024  KB05 T cell-activated C115(20.00)  LDD1710  [38]
 LDCM0169  KB63 Ramos 14.97  LDD0432  [22]
 LDCM0109  NEM HeLa N.A.  LDD0223  [27]
 LDCM0014  Panhematin HEK-293T 3.16  LDD0062  [21]
 LDCM0099  Phenelzine MDA-MB-231 3.00  LDD0392  [15]
 LDCM0090  Rapamycin JHH-7 6.16  LDD0213  [34]
 LDCM0084  Ro 48-8071 A-549 4.22  LDD0145  [33]
 LDCM0019  Staurosporine Hep-G2 N.A.  LDD0083  [35]
 LDCM0111  W14 Hep-G2 C115(18.23)  LDD0238  [13]
 LDCM0154  YY4 T cell 2.86  LDD0400  [19]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 5 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) EBP family Q15125
Phospholipid phosphatase 4 (PLPP4) PA-phosphatase related phosphoesterase family Q5VZY2
Phosphatase and actin regulator 3 (PHACTR3) Phosphatase and actin regulator family Q96KR7
Lysoplasmalogenase TMEM86B (TMEM86B) TMEM86 family Q8N661
E3 ubiquitin-protein ligase MARCHF8 (MARCHF8) . Q5T0T0
Transporter and channel
Click To Hide/Show 15 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Stomatin (STOM) Band 7/mec-2 family P27105
Sodium-dependent organic anion transporter (SLC10A6) Bile acid:sodium symporter (BASS) family Q3KNW5
Claudin-7 (CLDN7) Claudin family O95471
Novel acetylcholine receptor chaperone (TMEM35A) DoxX family Q53FP2
Hippocampus abundant transcript-like protein 1 (MFSD14B) Major facilitator superfamily Q5SR56
Molybdate-anion transporter (MFSD5) Major facilitator superfamily Q6N075
Sodium-dependent glucose transporter 1 (MFSD4B) Major facilitator superfamily Q5TF39
Aquaporin-6 (AQP6) MIP/aquaporin (TC 1.A.8) family Q13520
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (BNIP3L) NIP3 family O60238
Synaptotagmin-1 (SYT1) Synaptotagmin family P21579
Syntaxin-1A (STX1A) Syntaxin family Q16623
Transmembrane protein 41A (TMEM41A) TMEM41 family Q96HV5
Potassium channel subfamily K member 5 (KCNK5) Two pore domain potassium channel (TC 1.A.1.8) family O95279
Zinc transporter ZIP9 (SLC39A9) ZIP transporter (TC 2.A.5) family Q9NUM3
Transmembrane protein 139 (TMEM139) . Q8IV31
GPCR
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Probable G-protein coupled receptor 152 (GPR152) G-protein coupled receptor 1 family Q8TDT2
Immunoglobulin
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3) Immunoglobulin superfamily P43628
Myeloid cell surface antigen CD33 (CD33) SIGLEC (sialic acid binding Ig-like lectin) family P20138
B-cell antigen receptor complex-associated protein alpha chain (CD79A) . P11912
Other
Click To Hide/Show 13 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
NADH dehydrogenase 1 alpha subcomplex assembly factor 2 (NDUFAF2) Complex I NDUFA12 subunit family Q8N183
Complexin-4 (CPLX4) Complexin/synaphin family Q7Z7G2
Gap junction beta-5 protein (GJB5) Connexin family O95377
Receptor expression-enhancing protein 4 (REEP4) DP1 family Q9H6H4
Protein FAM209A (FAM209A) FAM209 family Q5JX71
Protein FAM210B, mitochondrial (FAM210B) FAM210 family Q96KR6
Reticulophagy regulator 3 (RETREG3) RETREG family Q86VR2
Succinate dehydrogenase assembly factor 4, mitochondrial (SDHAF4) SDHAF4 family Q5VUM1
Bcl-2-interacting killer (BIK) . Q13323
Cell growth regulator with RING finger domain protein 1 (CGRRF1) . Q99675
FERM domain-containing protein 3 (FRMD3) . A2A2Y4
Fibronectin type III domain-containing protein 9 (FNDC9) . Q8TBE3
PDZK1-interacting protein 1 (PDZK1IP1) . Q13113

The Drug(s) Related To This Target

Investigative
Click To Hide/Show 1 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Phenethyl Isothiocyanate Small molecular drug DB12695

References

1 Fatty Acyl Sulfonyl Fluoride as an Activity-Based Probe for Profiling Fatty Acid-Associated Proteins in Living Cells. Chembiochem. 2022 Feb 16;23(4):e202100628. doi: 10.1002/cbic.202100628. Epub 2021 Dec 30.
2 Comparison of Different Competitive Proteome Profiling Approaches in Target Identification of Covalent Inhibitors. Chembiochem. 2022 Dec 16;23(24):e202200389. doi: 10.1002/cbic.202200389. Epub 2022 Nov 22.
3 A Chemical Proteomic Analysis of Illudin-Interacting Proteins. Chemistry. 2019 Sep 25;25(54):12644-12651. doi: 10.1002/chem.201902919. Epub 2019 Sep 3.
Mass spectrometry data entry: PXD014175
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