Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name ILS-2  Probe Info 
Probe concentration 3 uM
Criteria Quantification: Probe vs DMSO
Quantitative Method
SILAC
In Vivo Experiment Model Model Type Living cell
Derived Tissue Lung
Disease Model Lung adenocarcinoma [ICD-11:2C25]
Model Name Human lung adenocarcinoma cells (A-549)

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 5 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00697  Cytochrome b5 type B (CYB5B) 4.5
 LDTP03560  Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) 4.1
 LDTP02198  Cathepsin D (CTSD) 3.7
 LDTP03540  Heme oxygenase 2 (HMOX2) 3.2
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 2.4
Transporter and channel
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 3.5
Other
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP12412  Reticulon-4 (RTN4) 2.4

References

1 A Chemical Proteomic Analysis of Illudin-Interacting Proteins. Chemistry. 2019 Sep 25;25(54):12644-12651. doi: 10.1002/chem.201902919. Epub 2019 Sep 3.
Mass spectrometry data entry: PXD014175