Probe Name	A-DA					Probe Info
Probe concentration	5 uM
Criteria	Quantification: Probe vs (Probe+Competitor)
Quantitative Method	SILAC
Competitor Name	Avasimibe					Competitor Info
Competitor Concentration	25 uM
In Vivo Experiment Model	Model Type			Living cell
	Derived Tissue			Lung
	Disease Model		Lung adenocarcinoma [ICD-11:2C25]
	Model Name		Human lung adenocarcinoma cells (A-549)

Target ID	Target Name					Binding Ratio
LDTP09542	1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (ABHD5)					20.0
LDTP11124	Ferroptosis suppressor protein 1 (AIFM2)					16.1
LDTP10077	Patatin-like phospholipase domain-containing protein 2 (PNPLA2)					8.1
LDTP10550	Dehydrogenase/reductase SDR family member 1 (DHRS1)					7.7
LDTP09666	Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1)					7.7
LDTP03912	Trifunctional enzyme subunit alpha, mitochondrial (HADHA)					5.1
LDTP09063	Estradiol 17-beta-dehydrogenase 11 (HSD17B11)					4.6
LDTP08722	Retinol dehydrogenase 10 (RDH10)					3.9
LDTP08900	Dehydrogenase/reductase SDR family member on chromosome X (DHRSX)					3.7
LDTP15484	Saccharopine dehydrogenase-like oxidoreductase (SCCPDH)					3.4
LDTP06455	Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (NSDHL)					3.2
LDTP01349	Short-chain dehydrogenase/reductase 3 (DHRS3)					3.0
LDTP03976	Aldo-keto reductase family 1 member C3 (AKR1C3)					2.8
LDTP12810	Tubulin alpha-8 chain (TUBA8)					2.7
LDTP06885	Glycerol-3-phosphate acyltransferase 3 (GPAT3)					2.7
LDTP05075	Tubulin alpha-4A chain (TUBA4A)					2.6
LDTP07907	Tubulin alpha-1A chain (TUBA1A)					2.5
LDTP06333	Serum paraoxonase/arylesterase 2 (PON2)					2.5
LDTP02175	Epoxide hydrolase 1 (EPHX1)					2.5
LDTP08859	Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4)					2.4
LDTP06142	Squalene monooxygenase (SQLE)					2.3
LDTP04183	Lanosterol synthase (LSS)					2.3
LDTP01770	NADH-cytochrome b5 reductase 3 (CYB5R3)					2.3
LDTP12470	GTP-binding protein SAR1a (SAR1A)					2.3
LDTP07963	Fatty acid 2-hydroxylase (FA2H)					2.1
LDTP01033	UDP-glucose 6-dehydrogenase (UGDH)					2.1
LDTP12293	Adipocyte plasma membrane-associated protein (APMAP)					2.1
LDTP06200	Delta(14)-sterol reductase LBR (LBR)					2.1
LDTP08799	Lysophosphatidylserine lipase ABHD12 (ABHD12)					2.1
LDTP01634	Fatty acid CoA ligase Acsl3 (ACSL3)					2.1
LDTP00697	Cytochrome b5 type B (CYB5B)					2.1
LDTP14231	GTP-binding protein SAR1b (SAR1B)					2.1
LDTP08017	Endoplasmic reticulum metallopeptidase 1 (ERMP1)					2.1
LDTP07504	Lysophospholipid acyltransferase 5 (LPCAT3)					2.1

Target ID	Target Name					Binding Ratio
LDTP07236	Protein GPR107 (GPR107)					2.6
LDTP00865	Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20)					2.6
LDTP05690	Vesicular integral-membrane protein VIP36 (LMAN2)					2.0

Target ID	Target Name					Binding Ratio
LDTP08950	ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1)					14.3
LDTP10889	Perilipin-2 (PLIN2)					9.0
LDTP10185	FAS-associated factor 2 (FAF2)					4.9
LDTP10567	Regulator of microtubule dynamics protein 2 (RMDN2)					4.9
LDTP00759	Tumor protein D54 (TPD52L2)					2.8
LDTP16080	Protein FAM114A2 (FAM114A2)					2.8
LDTP14217	Lipid droplet-regulating VLDL assembly factor AUP1 (AUP1)					2.8
LDTP01021	Perilipin-3 (PLIN3)					2.8
LDTP12412	Reticulon-4 (RTN4)					2.6
LDTP02205	Tubulin beta chain (TUBB)					2.4
LDTP05076	Tubulin beta-4B chain (TUBB4B)					2.3
LDTP11277	Tubulin beta-2B chain (TUBB2B)					2.3
LDTP05904	Tubulin beta-3 chain (TUBB3)					2.3
LDTP11233	Tubulin beta-6 chain (TUBB6)					2.2
LDTP11076	Apolipoprotein L2 (APOL2)					2.2
LDTP00850	ER lumen protein-retaining receptor 3 (KDELR3)					2.1

1	A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells. Cell. 2015 Jun 18;161(7):1668-80. doi: 10.1016/j.cell.2015.05.045.