Details of the Target

General Information of Target

Target ID LDTP16080
Target Name Protein FAM114A2 (FAM114A2)
Gene Name FAM114A2
Gene ID 10827
Synonyms
C5orf3; Protein FAM114A2
3D Structure
Download
2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MRLSVAAAISHGRVFRRMGLGPESRIHLLRNLLTGLVRHERIEAPWARVDEMRGYAEKLI
DYGKLGDTNERAMRMADFWLTEKDLIPKLFQVLAPRYKDQTGGYTRMLQIPNRSLDRAKM
AVIEYKGNCLPPLPLPRRDSHLTLLNQLLQGLRQDLRQSQEASNHSSHTAQTPGI
Target Bioclass
Other
Family
FAM114 family
Uniprot ID
Q9NRY5
Ensemble ID
ENST00000351797.9
HGNC ID
HGNC:1333

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 15 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
FBPP2
 Probe Info  		7.39  LDD0318  [2]
DA-P3
 Probe Info  		4.62  LDD0179  [3]
Alkyne-RA190
 Probe Info  		4.17  LDD0299  [4]
Acrolein
 Probe Info  		N.A.  LDD0225  [5]
DBIA
 Probe Info  		C425(1.03)  LDD0532  [6]
ATP probe
 Probe Info  		K182(0.00); K183(0.00)  LDD0199  [7]
4-Iodoacetamidophenylacetylene
 Probe Info  		C438(0.00); C388(0.00)  LDD0038  [8]
IA-alkyne
 Probe Info  		C438(0.00); C388(0.00); C425(0.00)  LDD0036  [8]
Lodoacetamide azide
 Probe Info  		C388(0.00); C296(0.00); C438(0.00); C425(0.00)  LDD0037  [8]
IPM
 Probe Info  		N.A.  LDD0005  [9]
TFBX
 Probe Info  		C438(0.00); C388(0.00)  LDD0148  [10]
VSF
 Probe Info  		C438(0.00); C24(0.00)  LDD0007  [9]
AOyne
 Probe Info  		15.00  LDD0443  [11]
NAIA_5
 Probe Info  		C438(0.00); C388(0.00); C425(0.00)  LDD2223  [12]
PAL-AfBPP Probe
Click To Hide/Show 157 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C004
 Probe Info  		7.78  LDD1714  [13]
C007
 Probe Info  		6.19  LDD1716  [13]
C008
 Probe Info  		5.17  LDD1717  [13]
C010
 Probe Info  		6.41  LDD1719  [13]
C017
 Probe Info  		6.68  LDD1725  [13]
C022
 Probe Info  		16.56  LDD1728  [13]
C040
 Probe Info  		18.64  LDD1740  [13]
C041
 Probe Info  		8.34  LDD1741  [13]
C049
 Probe Info  		5.70  LDD1747  [13]
C055
 Probe Info  		33.13  LDD1752  [13]
C056
 Probe Info  		66.26  LDD1753  [13]
C059
 Probe Info  		4.92  LDD1756  [13]
C060
 Probe Info  		6.36  LDD1757  [13]
C063
 Probe Info  		25.28  LDD1760  [13]
C064
 Probe Info  		8.40  LDD1761  [13]
C070
 Probe Info  		14.62  LDD1766  [13]
C072
 Probe Info  		8.46  LDD1768  [13]
C082
 Probe Info  		7.11  LDD1774  [13]
C085
 Probe Info  		5.10  LDD1777  [13]
C087
 Probe Info  		10.06  LDD1779  [13]
C091
 Probe Info  		44.02  LDD1782  [13]
C092
 Probe Info  		59.30  LDD1783  [13]
C094
 Probe Info  		52.35  LDD1785  [13]
C095
 Probe Info  		7.26  LDD1786  [13]
C100
 Probe Info  		6.54  LDD1789  [13]
C106
 Probe Info  		36.00  LDD1793  [13]
C107
 Probe Info  		10.48  LDD1794  [13]
C108
 Probe Info  		14.12  LDD1795  [13]
C112
 Probe Info  		50.56  LDD1799  [13]
C129
 Probe Info  		6.87  LDD1811  [13]
C130
 Probe Info  		9.99  LDD1812  [13]
C134
 Probe Info  		53.45  LDD1816  [13]
C135
 Probe Info  		22.63  LDD1817  [13]
C139
 Probe Info  		12.38  LDD1821  [13]
C140
 Probe Info  		8.94  LDD1822  [13]
C141
 Probe Info  		21.86  LDD1823  [13]
C143
 Probe Info  		41.07  LDD1825  [13]
C145
 Probe Info  		11.55  LDD1827  [13]
C147
 Probe Info  		9.06  LDD1829  [13]
C153
 Probe Info  		37.27  LDD1834  [13]
C159
 Probe Info  		11.08  LDD1839  [13]
C160
 Probe Info  		10.93  LDD1840  [13]
C161
 Probe Info  		13.83  LDD1841  [13]
C163
 Probe Info  		10.27  LDD1843  [13]
C166
 Probe Info  		7.94  LDD1846  [13]
C169
 Probe Info  		28.44  LDD1849  [13]
C177
 Probe Info  		7.94  LDD1856  [13]
C178
 Probe Info  		28.05  LDD1857  [13]
C186
 Probe Info  		8.57  LDD1864  [13]
C187
 Probe Info  		19.70  LDD1865  [13]
C191
 Probe Info  		10.93  LDD1868  [13]
C194
 Probe Info  		11.24  LDD1870  [13]
C196
 Probe Info  		15.03  LDD1872  [13]
C198
 Probe Info  		16.11  LDD1874  [13]
C201
 Probe Info  		97.68  LDD1877  [13]
C206
 Probe Info  		47.84  LDD1881  [13]
C207
 Probe Info  		19.97  LDD1882  [13]
C211
 Probe Info  		7.94  LDD1885  [13]
C213
 Probe Info  		16.22  LDD1887  [13]
C218
 Probe Info  		25.63  LDD1892  [13]
C219
 Probe Info  		7.67  LDD1893  [13]
C220
 Probe Info  		21.11  LDD1894  [13]
C225
 Probe Info  		10.20  LDD1898  [13]
C226
 Probe Info  		8.11  LDD1899  [13]
C228
 Probe Info  		49.87  LDD1901  [13]
C229
 Probe Info  		11.31  LDD1902  [13]
C231
 Probe Info  		32.90  LDD1904  [13]
C232
 Probe Info  		45.25  LDD1905  [13]
C233
 Probe Info  		18.00  LDD1906  [13]
C234
 Probe Info  		9.38  LDD1907  [13]
C235
 Probe Info  		50.91  LDD1908  [13]
C238
 Probe Info  		26.17  LDD1911  [13]
C240
 Probe Info  		12.30  LDD1913  [13]
C243
 Probe Info  		22.63  LDD1916  [13]
C244
 Probe Info  		18.13  LDD1917  [13]
C245
 Probe Info  		5.43  LDD1918  [13]
C246
 Probe Info  		19.84  LDD1919  [13]
C249
 Probe Info  		17.75  LDD1922  [13]
C252
 Probe Info  		19.03  LDD1925  [13]
C258
 Probe Info  		7.01  LDD1931  [13]
C264
 Probe Info  		41.93  LDD1935  [13]
C265
 Probe Info  		17.88  LDD1936  [13]
C269
 Probe Info  		8.28  LDD1939  [13]
C270
 Probe Info  		8.75  LDD1940  [13]
C273
 Probe Info  		6.15  LDD1943  [13]
C277
 Probe Info  		15.45  LDD1947  [13]
C278
 Probe Info  		94.35  LDD1948  [13]
C280
 Probe Info  		16.22  LDD1950  [13]
C282
 Probe Info  		53.82  LDD1952  [13]
C284
 Probe Info  		81.57  LDD1954  [13]
C285
 Probe Info  		53.45  LDD1955  [13]
C287
 Probe Info  		25.81  LDD1957  [13]
C288
 Probe Info  		13.64  LDD1958  [13]
C289
 Probe Info  		72.00  LDD1959  [13]
C290
 Probe Info  		7.73  LDD1960  [13]
C293
 Probe Info  		35.26  LDD1963  [13]
C296
 Probe Info  		32.45  LDD1966  [13]
C299
 Probe Info  		12.13  LDD1968  [13]
C301
 Probe Info  		5.28  LDD1970  [13]
C305
 Probe Info  		21.56  LDD1974  [13]
C307
 Probe Info  		6.06  LDD1975  [13]
C310
 Probe Info  		23.59  LDD1977  [13]
C313
 Probe Info  		16.00  LDD1980  [13]
C314
 Probe Info  		20.53  LDD1981  [13]
C317
 Probe Info  		9.65  LDD1983  [13]
C322
 Probe Info  		6.41  LDD1988  [13]
C326
 Probe Info  		13.09  LDD1990  [13]
C339
 Probe Info  		10.41  LDD2002  [13]
C343
 Probe Info  		23.26  LDD2005  [13]
C348
 Probe Info  		11.96  LDD2009  [13]
C349
 Probe Info  		18.51  LDD2010  [13]
C350
 Probe Info  		48.50  LDD2011  [13]
C354
 Probe Info  		9.13  LDD2015  [13]
C355
 Probe Info  		70.52  LDD2016  [13]
C356
 Probe Info  		18.25  LDD2017  [13]
C357
 Probe Info  		8.51  LDD2018  [13]
C361
 Probe Info  		18.90  LDD2022  [13]
C362
 Probe Info  		65.80  LDD2023  [13]
C363
 Probe Info  		22.94  LDD2024  [13]
C364
 Probe Info  		21.71  LDD2025  [13]
C366
 Probe Info  		11.63  LDD2027  [13]
C367
 Probe Info  		7.06  LDD2028  [13]
C373
 Probe Info  		6.15  LDD2033  [13]
C376
 Probe Info  		15.14  LDD2036  [13]
C378
 Probe Info  		7.36  LDD2037  [13]
C380
 Probe Info  		6.11  LDD2039  [13]
C382
 Probe Info  		19.97  LDD2041  [13]
C383
 Probe Info  		15.78  LDD2042  [13]
C386
 Probe Info  		9.00  LDD2045  [13]
C388
 Probe Info  		76.11  LDD2047  [13]
C390
 Probe Info  		49.87  LDD2049  [13]
C391
 Probe Info  		18.00  LDD2050  [13]
C397
 Probe Info  		10.27  LDD2056  [13]
C399
 Probe Info  		16.11  LDD2058  [13]
C403
 Probe Info  		26.72  LDD2061  [13]
C407
 Probe Info  		31.56  LDD2064  [13]
C409
 Probe Info  		5.98  LDD2066  [13]
C413
 Probe Info  		34.30  LDD2069  [13]
C419
 Probe Info  		15.67  LDD2074  [13]
C420
 Probe Info  		19.03  LDD2075  [13]
C424
 Probe Info  		14.72  LDD2079  [13]
C426
 Probe Info  		20.11  LDD2081  [13]
C429
 Probe Info  		23.10  LDD2084  [13]
C431
 Probe Info  		32.22  LDD2086  [13]
C433
 Probe Info  		7.31  LDD2088  [13]
FFF probe11
 Probe Info  		20.00  LDD0471  [14]
FFF probe13
 Probe Info  		20.00  LDD0475  [14]
FFF probe14
 Probe Info  		20.00  LDD0477  [14]
FFF probe15
 Probe Info  		9.91  LDD0478  [14]
FFF probe2
 Probe Info  		20.00  LDD0463  [14]
FFF probe3
 Probe Info  		20.00  LDD0464  [14]
FFF probe4
 Probe Info  		20.00  LDD0466  [14]
FFF probe6
 Probe Info  		20.00  LDD0467  [14]
FFF probe9
 Probe Info  		20.00  LDD0485  [14]
JN0003
 Probe Info  		20.00  LDD0469  [14]
A-DA
 Probe Info  		2.77  LDD0143  [15]
OEA-DA
 Probe Info  		20.00  LDD0046  [16]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 PaTu 8988t C388(1.33); C425(1.17)  LDD1093  [6]
 LDCM0215  AC10 HCT 116 C425(1.03)  LDD0532  [6]
 LDCM0216  AC100 HCT 116 C425(0.80)  LDD0533  [6]
 LDCM0217  AC101 HCT 116 C425(0.76)  LDD0534  [6]
 LDCM0218  AC102 HCT 116 C425(0.79)  LDD0535  [6]
 LDCM0219  AC103 HCT 116 C425(0.92)  LDD0536  [6]
 LDCM0220  AC104 HCT 116 C425(0.97)  LDD0537  [6]
 LDCM0221  AC105 HCT 116 C425(0.91)  LDD0538  [6]
 LDCM0222  AC106 HCT 116 C425(1.04)  LDD0539  [6]
 LDCM0223  AC107 HCT 116 C425(0.96)  LDD0540  [6]
 LDCM0224  AC108 HCT 116 C425(0.88)  LDD0541  [6]
 LDCM0225  AC109 HCT 116 C425(0.83)  LDD0542  [6]
 LDCM0226  AC11 HCT 116 C425(1.06)  LDD0543  [6]
 LDCM0227  AC110 HCT 116 C425(0.92)  LDD0544  [6]
 LDCM0228  AC111 HCT 116 C425(0.76)  LDD0545  [6]
 LDCM0229  AC112 HCT 116 C425(0.91)  LDD0546  [6]
 LDCM0230  AC113 PaTu 8988t C388(1.06); C425(1.00)  LDD1109  [6]
 LDCM0231  AC114 PaTu 8988t C388(0.96); C425(0.93)  LDD1110  [6]
 LDCM0232  AC115 PaTu 8988t C388(0.97); C425(1.00)  LDD1111  [6]
 LDCM0233  AC116 PaTu 8988t C388(0.88); C425(1.00)  LDD1112  [6]
 LDCM0234  AC117 PaTu 8988t C388(1.10); C425(1.17)  LDD1113  [6]
 LDCM0235  AC118 PaTu 8988t C388(1.07); C425(1.02)  LDD1114  [6]
 LDCM0236  AC119 PaTu 8988t C388(1.13); C425(1.02)  LDD1115  [6]
 LDCM0237  AC12 HCT 116 C425(1.13)  LDD0554  [6]
 LDCM0238  AC120 PaTu 8988t C388(1.11); C425(1.01)  LDD1117  [6]
 LDCM0239  AC121 PaTu 8988t C388(1.14); C425(1.10)  LDD1118  [6]
 LDCM0240  AC122 PaTu 8988t C388(0.94); C425(0.92)  LDD1119  [6]
 LDCM0241  AC123 PaTu 8988t C388(1.06); C425(0.93)  LDD1120  [6]
 LDCM0242  AC124 PaTu 8988t C388(1.10); C425(0.84)  LDD1121  [6]
 LDCM0243  AC125 PaTu 8988t C388(1.07); C425(0.85)  LDD1122  [6]
 LDCM0244  AC126 PaTu 8988t C388(0.97); C425(0.86)  LDD1123  [6]
 LDCM0245  AC127 PaTu 8988t C388(1.24); C425(1.01)  LDD1124  [6]
 LDCM0246  AC128 HCT 116 C425(1.06)  LDD0563  [6]
 LDCM0247  AC129 HCT 116 C425(1.05)  LDD0564  [6]
 LDCM0249  AC130 HCT 116 C425(1.22)  LDD0566  [6]
 LDCM0250  AC131 HCT 116 C425(1.24)  LDD0567  [6]
 LDCM0251  AC132 HCT 116 C425(1.31)  LDD0568  [6]
 LDCM0252  AC133 HCT 116 C425(1.22)  LDD0569  [6]
 LDCM0253  AC134 HCT 116 C425(1.43)  LDD0570  [6]
 LDCM0254  AC135 HCT 116 C425(1.10)  LDD0571  [6]
 LDCM0255  AC136 HCT 116 C425(1.15)  LDD0572  [6]
 LDCM0256  AC137 HCT 116 C425(1.01)  LDD0573  [6]
 LDCM0257  AC138 HCT 116 C425(1.33)  LDD0574  [6]
 LDCM0258  AC139 HCT 116 C425(1.34)  LDD0575  [6]
 LDCM0259  AC14 HCT 116 C425(1.12)  LDD0576  [6]
 LDCM0260  AC140 HCT 116 C425(1.47)  LDD0577  [6]
 LDCM0261  AC141 HCT 116 C425(1.29)  LDD0578  [6]
 LDCM0262  AC142 HCT 116 C425(1.11)  LDD0579  [6]
 LDCM0263  AC143 PaTu 8988t C388(1.37); C425(0.93)  LDD1142  [6]
 LDCM0264  AC144 PaTu 8988t C388(1.08); C425(0.85)  LDD1143  [6]
 LDCM0265  AC145 PaTu 8988t C388(1.16); C425(0.77)  LDD1144  [6]
 LDCM0266  AC146 PaTu 8988t C388(0.89); C425(0.88)  LDD1145  [6]
 LDCM0267  AC147 PaTu 8988t C388(1.16); C425(0.86)  LDD1146  [6]
 LDCM0268  AC148 PaTu 8988t C388(1.25); C425(1.07)  LDD1147  [6]
 LDCM0269  AC149 PaTu 8988t C388(1.33); C425(1.09)  LDD1148  [6]
 LDCM0270  AC15 HCT 116 C425(1.08)  LDD0587  [6]
 LDCM0271  AC150 PaTu 8988t C388(1.09); C425(0.98)  LDD1150  [6]
 LDCM0272  AC151 PaTu 8988t C388(1.08); C425(1.24)  LDD1151  [6]
 LDCM0273  AC152 PaTu 8988t C388(1.48); C425(1.00)  LDD1152  [6]
 LDCM0274  AC153 PaTu 8988t C388(1.35); C425(0.97)  LDD1153  [6]
 LDCM0621  AC154 PaTu 8988t C388(1.11); C425(1.32)  LDD2166  [6]
 LDCM0622  AC155 PaTu 8988t C388(1.18); C425(1.04)  LDD2167  [6]
 LDCM0623  AC156 PaTu 8988t C388(1.20); C425(0.91)  LDD2168  [6]
 LDCM0624  AC157 PaTu 8988t C388(1.10); C425(1.18)  LDD2169  [6]
 LDCM0276  AC17 HCT 116 C425(0.89)  LDD0593  [6]
 LDCM0277  AC18 HCT 116 C425(0.90)  LDD0594  [6]
 LDCM0278  AC19 HCT 116 C425(0.84)  LDD0595  [6]
 LDCM0279  AC2 PaTu 8988t C388(1.10); C425(1.00)  LDD1158  [6]
 LDCM0280  AC20 HCT 116 C425(0.83)  LDD0597  [6]
 LDCM0281  AC21 HCT 116 C425(0.87)  LDD0598  [6]
 LDCM0282  AC22 HCT 116 C425(0.77)  LDD0599  [6]
 LDCM0283  AC23 HCT 116 C425(0.98)  LDD0600  [6]
 LDCM0284  AC24 HCT 116 C425(0.89)  LDD0601  [6]
 LDCM0285  AC25 HCT 116 C425(1.03)  LDD0602  [6]
 LDCM0286  AC26 HCT 116 C425(1.16)  LDD0603  [6]
 LDCM0287  AC27 HCT 116 C425(1.12)  LDD0604  [6]
 LDCM0288  AC28 HCT 116 C425(1.10)  LDD0605  [6]
 LDCM0289  AC29 HCT 116 C425(1.05)  LDD0606  [6]
 LDCM0290  AC3 PaTu 8988t C388(1.13); C425(1.12)  LDD1169  [6]
 LDCM0291  AC30 HCT 116 C425(1.14)  LDD0608  [6]
 LDCM0292  AC31 HCT 116 C425(1.19)  LDD0609  [6]
 LDCM0293  AC32 HCT 116 C425(1.19)  LDD0610  [6]
 LDCM0294  AC33 HCT 116 C425(1.12)  LDD0611  [6]
 LDCM0295  AC34 HCT 116 C425(1.12)  LDD0612  [6]
 LDCM0296  AC35 HCT 116 C425(0.84)  LDD0613  [6]
 LDCM0297  AC36 HCT 116 C425(0.98)  LDD0614  [6]
 LDCM0298  AC37 HCT 116 C425(1.07)  LDD0615  [6]
 LDCM0299  AC38 HCT 116 C425(1.01)  LDD0616  [6]
 LDCM0300  AC39 HCT 116 C425(1.07)  LDD0617  [6]
 LDCM0301  AC4 PaTu 8988t C388(1.01); C425(0.97)  LDD1180  [6]
 LDCM0302  AC40 HCT 116 C425(1.15)  LDD0619  [6]
 LDCM0303  AC41 HCT 116 C425(1.06)  LDD0620  [6]
 LDCM0304  AC42 HCT 116 C425(1.02)  LDD0621  [6]
 LDCM0305  AC43 HCT 116 C425(1.05)  LDD0622  [6]
 LDCM0306  AC44 HCT 116 C425(1.15)  LDD0623  [6]
 LDCM0307  AC45 HCT 116 C425(1.13)  LDD0624  [6]
 LDCM0308  AC46 HCT 116 C425(1.08)  LDD0625  [6]
 LDCM0309  AC47 HCT 116 C425(1.12)  LDD0626  [6]
 LDCM0310  AC48 HCT 116 C425(1.04)  LDD0627  [6]
 LDCM0311  AC49 HCT 116 C425(1.16)  LDD0628  [6]
 LDCM0312  AC5 PaTu 8988t C388(1.22); C425(1.19)  LDD1191  [6]
 LDCM0313  AC50 HCT 116 C425(1.08)  LDD0630  [6]
 LDCM0314  AC51 HCT 116 C425(0.88)  LDD0631  [6]
 LDCM0315  AC52 HCT 116 C425(0.98)  LDD0632  [6]
 LDCM0316  AC53 HCT 116 C425(1.08)  LDD0633  [6]
 LDCM0317  AC54 HCT 116 C425(1.13)  LDD0634  [6]
 LDCM0318  AC55 HCT 116 C425(1.20)  LDD0635  [6]
 LDCM0319  AC56 HCT 116 C425(1.35)  LDD0636  [6]
 LDCM0320  AC57 HCT 116 C425(1.08)  LDD0637  [6]
 LDCM0321  AC58 HCT 116 C425(1.13)  LDD0638  [6]
 LDCM0322  AC59 HCT 116 C425(1.17)  LDD0639  [6]
 LDCM0323  AC6 HCT 116 C425(1.21)  LDD0640  [6]
 LDCM0324  AC60 HCT 116 C425(1.20)  LDD0641  [6]
 LDCM0325  AC61 HCT 116 C425(1.04)  LDD0642  [6]
 LDCM0326  AC62 HCT 116 C425(1.16)  LDD0643  [6]
 LDCM0327  AC63 HCT 116 C425(1.11)  LDD0644  [6]
 LDCM0328  AC64 HCT 116 C425(1.37)  LDD0645  [6]
 LDCM0329  AC65 HCT 116 C425(1.44)  LDD0646  [6]
 LDCM0330  AC66 HCT 116 C425(1.41)  LDD0647  [6]
 LDCM0331  AC67 HCT 116 C425(1.36)  LDD0648  [6]
 LDCM0332  AC68 PaTu 8988t C388(0.97)  LDD1211  [6]
 LDCM0333  AC69 PaTu 8988t C388(0.93)  LDD1212  [6]
 LDCM0334  AC7 HCT 116 C425(1.27)  LDD0651  [6]
 LDCM0335  AC70 PaTu 8988t C388(0.94)  LDD1214  [6]
 LDCM0336  AC71 PaTu 8988t C388(0.91)  LDD1215  [6]
 LDCM0337  AC72 PaTu 8988t C388(0.97)  LDD1216  [6]
 LDCM0338  AC73 PaTu 8988t C388(1.04)  LDD1217  [6]
 LDCM0339  AC74 PaTu 8988t C388(1.02)  LDD1218  [6]
 LDCM0340  AC75 PaTu 8988t C388(1.02)  LDD1219  [6]
 LDCM0341  AC76 PaTu 8988t C388(0.92)  LDD1220  [6]
 LDCM0342  AC77 PaTu 8988t C388(0.90)  LDD1221  [6]
 LDCM0343  AC78 PaTu 8988t C388(0.92)  LDD1222  [6]
 LDCM0344  AC79 PaTu 8988t C388(0.97)  LDD1223  [6]
 LDCM0345  AC8 HCT 116 C425(1.02)  LDD0662  [6]
 LDCM0346  AC80 PaTu 8988t C388(0.97)  LDD1225  [6]
 LDCM0347  AC81 PaTu 8988t C388(0.97)  LDD1226  [6]
 LDCM0348  AC82 PaTu 8988t C388(1.03)  LDD1227  [6]
 LDCM0349  AC83 HCT 116 C425(1.22)  LDD0666  [6]
 LDCM0350  AC84 HCT 116 C425(1.06)  LDD0667  [6]
 LDCM0351  AC85 HCT 116 C425(1.01)  LDD0668  [6]
 LDCM0352  AC86 HCT 116 C425(0.92)  LDD0669  [6]
 LDCM0353  AC87 HCT 116 C425(0.80)  LDD0670  [6]
 LDCM0354  AC88 HCT 116 C425(0.92)  LDD0671  [6]
 LDCM0355  AC89 HCT 116 C425(0.95)  LDD0672  [6]
 LDCM0357  AC90 HCT 116 C425(0.84)  LDD0674  [6]
 LDCM0358  AC91 HCT 116 C425(1.23)  LDD0675  [6]
 LDCM0359  AC92 HCT 116 C425(1.10)  LDD0676  [6]
 LDCM0360  AC93 HCT 116 C425(0.81)  LDD0677  [6]
 LDCM0361  AC94 HCT 116 C425(0.86)  LDD0678  [6]
 LDCM0362  AC95 HCT 116 C425(0.77)  LDD0679  [6]
 LDCM0363  AC96 HCT 116 C425(0.87)  LDD0680  [6]
 LDCM0364  AC97 HCT 116 C425(0.90)  LDD0681  [6]
 LDCM0365  AC98 HCT 116 C425(0.81)  LDD0682  [6]
 LDCM0366  AC99 HCT 116 C425(0.79)  LDD0683  [6]
 LDCM0248  AKOS034007472 HCT 116 C425(1.15)  LDD0565  [6]
 LDCM0356  AKOS034007680 HCT 116 C425(1.13)  LDD0673  [6]
 LDCM0275  AKOS034007705 HCT 116 C425(1.43)  LDD0592  [6]
 LDCM0156  Aniline NCI-H1299 13.67  LDD0403  [1]
 LDCM0083  Avasimibe A-549 2.77  LDD0143  [15]
 LDCM0632  CL-Sc Hep-G2 C425(2.10); C388(0.48)  LDD2227  [12]
 LDCM0367  CL1 PaTu 8988t C425(0.87)  LDD1246  [6]
 LDCM0368  CL10 PaTu 8988t C425(0.90)  LDD1247  [6]
 LDCM0369  CL100 PaTu 8988t C388(1.05); C425(0.91)  LDD1248  [6]
 LDCM0370  CL101 HCT 116 C425(1.14)  LDD0687  [6]
 LDCM0371  CL102 HCT 116 C425(1.22)  LDD0688  [6]
 LDCM0372  CL103 HCT 116 C425(1.16)  LDD0689  [6]
 LDCM0373  CL104 HCT 116 C425(1.01)  LDD0690  [6]
 LDCM0374  CL105 HCT 116 C425(0.86)  LDD0691  [6]
 LDCM0375  CL106 HCT 116 C425(0.91)  LDD0692  [6]
 LDCM0376  CL107 HCT 116 C425(0.99)  LDD0693  [6]
 LDCM0377  CL108 HCT 116 C425(0.95)  LDD0694  [6]
 LDCM0378  CL109 HCT 116 C425(0.89)  LDD0695  [6]
 LDCM0379  CL11 PaTu 8988t C425(0.96)  LDD1258  [6]
 LDCM0380  CL110 HCT 116 C425(0.95)  LDD0697  [6]
 LDCM0381  CL111 HCT 116 C425(0.89)  LDD0698  [6]
 LDCM0382  CL112 HCT 116 C425(1.07)  LDD0699  [6]
 LDCM0383  CL113 HCT 116 C425(1.01)  LDD0700  [6]
 LDCM0384  CL114 HCT 116 C425(1.03)  LDD0701  [6]
 LDCM0385  CL115 HCT 116 C425(1.04)  LDD0702  [6]
 LDCM0386  CL116 HCT 116 C425(1.13)  LDD0703  [6]
 LDCM0387  CL117 HCT 116 C425(1.25)  LDD0704  [6]
 LDCM0388  CL118 HCT 116 C425(1.13)  LDD0705  [6]
 LDCM0389  CL119 HCT 116 C425(1.05)  LDD0706  [6]
 LDCM0390  CL12 PaTu 8988t C425(0.91)  LDD1269  [6]
 LDCM0391  CL120 HCT 116 C425(1.07)  LDD0708  [6]
 LDCM0392  CL121 HCT 116 C425(1.02)  LDD0709  [6]
 LDCM0393  CL122 HCT 116 C425(1.13)  LDD0710  [6]
 LDCM0394  CL123 HCT 116 C425(1.07)  LDD0711  [6]
 LDCM0395  CL124 HCT 116 C425(1.14)  LDD0712  [6]
 LDCM0396  CL125 HCT 116 C425(0.92)  LDD0713  [6]
 LDCM0397  CL126 HCT 116 C425(0.96)  LDD0714  [6]
 LDCM0398  CL127 HCT 116 C425(0.94)  LDD0715  [6]
 LDCM0399  CL128 HCT 116 C425(1.10)  LDD0716  [6]
 LDCM0400  CL13 PaTu 8988t C425(1.11)  LDD1279  [6]
 LDCM0401  CL14 PaTu 8988t C425(0.99)  LDD1280  [6]
 LDCM0402  CL15 PaTu 8988t C425(0.83)  LDD1281  [6]
 LDCM0403  CL16 HCT 116 C425(1.09)  LDD0720  [6]
 LDCM0404  CL17 HCT 116 C425(0.92)  LDD0721  [6]
 LDCM0405  CL18 HCT 116 C425(0.95)  LDD0722  [6]
 LDCM0406  CL19 HCT 116 C425(1.14)  LDD0723  [6]
 LDCM0407  CL2 PaTu 8988t C425(0.78)  LDD1286  [6]
 LDCM0408  CL20 HCT 116 C425(1.59)  LDD0725  [6]
 LDCM0409  CL21 HCT 116 C425(1.15)  LDD0726  [6]
 LDCM0410  CL22 HCT 116 C425(1.59)  LDD0727  [6]
 LDCM0411  CL23 HCT 116 C425(1.20)  LDD0728  [6]
 LDCM0412  CL24 HCT 116 C425(1.47)  LDD0729  [6]
 LDCM0413  CL25 HCT 116 C425(1.23)  LDD0730  [6]
 LDCM0414  CL26 HCT 116 C425(1.12)  LDD0731  [6]
 LDCM0415  CL27 HCT 116 C425(1.00)  LDD0732  [6]
 LDCM0416  CL28 HCT 116 C425(1.14)  LDD0733  [6]
 LDCM0417  CL29 HCT 116 C425(1.31)  LDD0734  [6]
 LDCM0418  CL3 PaTu 8988t C425(0.80)  LDD1297  [6]
 LDCM0419  CL30 HCT 116 C425(1.07)  LDD0736  [6]
 LDCM0420  CL31 PaTu 8988t C388(0.95); C425(1.09)  LDD1299  [6]
 LDCM0421  CL32 PaTu 8988t C388(0.99); C425(1.09)  LDD1300  [6]
 LDCM0422  CL33 PaTu 8988t C388(0.86); C425(0.97)  LDD1301  [6]
 LDCM0423  CL34 PaTu 8988t C388(1.00); C425(1.05)  LDD1302  [6]
 LDCM0424  CL35 PaTu 8988t C388(1.04); C425(1.08)  LDD1303  [6]
 LDCM0425  CL36 PaTu 8988t C388(0.68); C425(0.75)  LDD1304  [6]
 LDCM0426  CL37 PaTu 8988t C388(1.09); C425(1.24)  LDD1305  [6]
 LDCM0428  CL39 PaTu 8988t C388(0.97); C425(1.07)  LDD1307  [6]
 LDCM0429  CL4 PaTu 8988t C425(0.88)  LDD1308  [6]
 LDCM0430  CL40 PaTu 8988t C388(0.95); C425(0.98)  LDD1309  [6]
 LDCM0431  CL41 PaTu 8988t C388(0.95); C425(1.20)  LDD1310  [6]
 LDCM0432  CL42 PaTu 8988t C388(1.20); C425(1.25)  LDD1311  [6]
 LDCM0433  CL43 PaTu 8988t C388(1.29); C425(1.49)  LDD1312  [6]
 LDCM0434  CL44 PaTu 8988t C388(1.00); C425(1.20)  LDD1313  [6]
 LDCM0435  CL45 PaTu 8988t C388(1.03); C425(1.10)  LDD1314  [6]
 LDCM0436  CL46 HCT 116 C425(0.83)  LDD0753  [6]
 LDCM0437  CL47 HCT 116 C425(0.77)  LDD0754  [6]
 LDCM0438  CL48 HCT 116 C425(0.80)  LDD0755  [6]
 LDCM0439  CL49 HCT 116 C425(0.88)  LDD0756  [6]
 LDCM0440  CL5 PaTu 8988t C425(0.97)  LDD1319  [6]
 LDCM0441  CL50 HCT 116 C425(0.90)  LDD0758  [6]
 LDCM0442  CL51 HCT 116 C425(0.94)  LDD0759  [6]
 LDCM0443  CL52 HCT 116 C425(0.81)  LDD0760  [6]
 LDCM0444  CL53 HCT 116 C425(0.82)  LDD0761  [6]
 LDCM0445  CL54 HCT 116 C425(0.79)  LDD0762  [6]
 LDCM0446  CL55 HCT 116 C425(0.80)  LDD0763  [6]
 LDCM0447  CL56 HCT 116 C425(0.92)  LDD0764  [6]
 LDCM0448  CL57 HCT 116 C425(0.82)  LDD0765  [6]
 LDCM0449  CL58 HCT 116 C425(0.89)  LDD0766  [6]
 LDCM0450  CL59 HCT 116 C425(0.83)  LDD0767  [6]
 LDCM0451  CL6 PaTu 8988t C425(0.90)  LDD1330  [6]
 LDCM0452  CL60 HCT 116 C425(0.92)  LDD0769  [6]
 LDCM0453  CL61 HCT 116 C425(1.03)  LDD0770  [6]
 LDCM0454  CL62 HCT 116 C425(0.96)  LDD0771  [6]
 LDCM0455  CL63 HCT 116 C425(1.32)  LDD0772  [6]
 LDCM0456  CL64 HCT 116 C425(1.17)  LDD0773  [6]
 LDCM0457  CL65 HCT 116 C425(1.18)  LDD0774  [6]
 LDCM0458  CL66 HCT 116 C425(1.26)  LDD0775  [6]
 LDCM0459  CL67 HCT 116 C425(1.14)  LDD0776  [6]
 LDCM0460  CL68 HCT 116 C425(1.10)  LDD0777  [6]
 LDCM0461  CL69 HCT 116 C425(0.93)  LDD0778  [6]
 LDCM0462  CL7 PaTu 8988t C425(1.13)  LDD1341  [6]
 LDCM0463  CL70 HCT 116 C425(0.91)  LDD0780  [6]
 LDCM0464  CL71 HCT 116 C425(0.99)  LDD0781  [6]
 LDCM0465  CL72 HCT 116 C425(1.05)  LDD0782  [6]
 LDCM0466  CL73 HCT 116 C425(1.16)  LDD0783  [6]
 LDCM0467  CL74 HCT 116 C425(0.98)  LDD0784  [6]
 LDCM0469  CL76 PaTu 8988t C388(0.87); C425(1.17)  LDD1348  [6]
 LDCM0470  CL77 PaTu 8988t C388(0.94); C425(1.22)  LDD1349  [6]
 LDCM0471  CL78 PaTu 8988t C388(0.96); C425(1.19)  LDD1350  [6]
 LDCM0472  CL79 PaTu 8988t C388(0.98); C425(1.18)  LDD1351  [6]
 LDCM0473  CL8 PaTu 8988t C425(0.91)  LDD1352  [6]
 LDCM0474  CL80 PaTu 8988t C388(0.95); C425(1.16)  LDD1353  [6]
 LDCM0475  CL81 PaTu 8988t C388(1.09); C425(1.24)  LDD1354  [6]
 LDCM0476  CL82 PaTu 8988t C388(1.04); C425(1.38)  LDD1355  [6]
 LDCM0477  CL83 PaTu 8988t C388(0.98); C425(1.24)  LDD1356  [6]
 LDCM0478  CL84 PaTu 8988t C388(1.03); C425(1.30)  LDD1357  [6]
 LDCM0479  CL85 PaTu 8988t C388(0.90); C425(1.05)  LDD1358  [6]
 LDCM0480  CL86 PaTu 8988t C388(0.98); C425(1.19)  LDD1359  [6]
 LDCM0481  CL87 PaTu 8988t C388(1.09); C425(1.26)  LDD1360  [6]
 LDCM0482  CL88 PaTu 8988t C388(1.09); C425(1.45)  LDD1361  [6]
 LDCM0483  CL89 PaTu 8988t C388(1.10); C425(1.24)  LDD1362  [6]
 LDCM0484  CL9 PaTu 8988t C425(0.99)  LDD1363  [6]
 LDCM0485  CL90 PaTu 8988t C388(1.02); C425(1.32)  LDD1364  [6]
 LDCM0486  CL91 PaTu 8988t C388(1.01); C425(0.98)  LDD1365  [6]
 LDCM0487  CL92 PaTu 8988t C388(0.94); C425(0.95)  LDD1366  [6]
 LDCM0488  CL93 PaTu 8988t C388(1.04); C425(0.88)  LDD1367  [6]
 LDCM0489  CL94 PaTu 8988t C388(1.16); C425(0.96)  LDD1368  [6]
 LDCM0490  CL95 PaTu 8988t C388(1.06); C425(0.99)  LDD1369  [6]
 LDCM0491  CL96 PaTu 8988t C388(0.99); C425(0.82)  LDD1370  [6]
 LDCM0492  CL97 PaTu 8988t C388(1.09); C425(1.02)  LDD1371  [6]
 LDCM0493  CL98 PaTu 8988t C388(1.27); C425(0.97)  LDD1372  [6]
 LDCM0494  CL99 PaTu 8988t C388(1.08); C425(0.92)  LDD1373  [6]
 LDCM0191  Compound 21 HEK-293T 8.10  LDD0508  [14]
 LDCM0190  Compound 34 HEK-293T 5.78  LDD0510  [14]
 LDCM0192  Compound 35 HEK-293T 6.47  LDD0509  [14]
 LDCM0193  Compound 36 HEK-293T 9.22  LDD0511  [14]
 LDCM0027  Dopamine HEK-293T 4.62  LDD0179  [3]
 LDCM0495  E2913 HEK-293T C438(0.99); C296(0.90); C388(0.94); C425(1.03)  LDD1698  [17]
 LDCM0625  F8 Ramos C438(0.70); C425(0.48)  LDD2187  [18]
 LDCM0572  Fragment10 Ramos C438(1.37)  LDD2189  [18]
 LDCM0573  Fragment11 Ramos C438(0.70); C425(6.72)  LDD2190  [18]
 LDCM0575  Fragment13 Ramos C438(1.52)  LDD2192  [18]
 LDCM0576  Fragment14 Ramos C438(3.60); C425(3.92)  LDD2193  [18]
 LDCM0580  Fragment21 Ramos C438(1.06)  LDD2195  [18]
 LDCM0578  Fragment27 Ramos C438(1.01)  LDD2197  [18]
 LDCM0588  Fragment30 Ramos C438(1.03); C425(0.31)  LDD2199  [18]
 LDCM0589  Fragment31 Ramos C438(1.66)  LDD2200  [18]
 LDCM0590  Fragment32 Ramos C438(1.46)  LDD2201  [18]
 LDCM0468  Fragment33 HCT 116 C425(1.22)  LDD0785  [6]
 LDCM0596  Fragment38 Ramos C438(0.86); C425(0.72)  LDD2203  [18]
 LDCM0566  Fragment4 Ramos C438(1.22)  LDD2184  [18]
 LDCM0427  Fragment51 PaTu 8988t C388(1.01); C425(1.06)  LDD1306  [6]
 LDCM0610  Fragment52 Ramos C438(0.99)  LDD2204  [18]
 LDCM0614  Fragment56 Ramos C438(0.77); C425(0.42)  LDD2205  [18]
 LDCM0569  Fragment7 Ramos C438(1.38); C425(0.61)  LDD2186  [18]
 LDCM0022  KB02 HEK-293T C438(1.02); C296(0.90); C425(1.04); C388(0.90)  LDD1492  [17]
 LDCM0023  KB03 HEK-293T C438(0.98); C296(0.97); C425(0.95); C388(0.97)  LDD1497  [17]
 LDCM0024  KB05 G361 C438(3.63)  LDD3311  [19]
 LDCM0109  NEM HeLa N.A.  LDD0225  [5]
 LDCM0131  RA190 MM1.R 4.17  LDD0299  [4]
 LDCM0084  Ro 48-8071 A-549 20.00  LDD0145  [15]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 6 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
NADH dehydrogenase flavoprotein 2, mitochondrial (NDUFV2) Complex I 24 kDa subunit family P19404
FAST kinase domain-containing protein 4 (TBRG4) FAST kinase family Q969Z0
Glutamate decarboxylase 2 (GAD2) Group II decarboxylase family Q05329
Tyrosine-protein phosphatase non-receptor type 9 (PTPN9) Protein-tyrosine phosphatase family P43378
Ras-related protein Rab-2A (RAB2A) Rab family P61019
Ras-related protein Rab-2B (RAB2B) Rab family Q8WUD1
Transporter and channel
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Endophilin-B1 (SH3GLB1) Endophilin family Q9Y371
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Alpha-tocopherol transfer protein (TTPA) . P49638

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Tranylcypromine specificity for monoamine oxidase is limited by promiscuous protein labelling and lysosomal trapping. RSC Chem Biol. 2020 Aug 12;1(4):209-213. doi: 10.1039/d0cb00048e. eCollection 2020 Oct 1.
Mass spectrometry data entry: PXD018580
3 A chemical probe unravels the reactive proteome of health-associated catechols. Chem Sci. 2023 Jul 22;14(32):8635-8643. doi: 10.1039/d3sc00888f. eCollection 2023 Aug 16.
Mass spectrometry data entry: PXD043348
4 Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.
5 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
6 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
7 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
8 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
9 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
10 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
11 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
12 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
13 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
14 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
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Mass spectrometry data entry: PXD007570
17 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
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Mass spectrometry data entry: PXD027578
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Mass spectrometry data entry: PXD047840