Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C134  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 147 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11321  Acetyl-CoA acetyltransferase, cytosolic (ACAT2) 99.7
 LDTP11187  COP9 signalosome complex subunit 4 (COPS4) 99.7
 LDTP00486  Cytochrome b-c1 complex subunit 8 (UQCRQ) 99.7
 LDTP00697  Cytochrome b5 type B (CYB5B) 99.7
 LDTP13189  Cytochrome b-c1 complex subunit 9 (UQCR10) 84.4
 LDTP02359  Heme oxygenase 1 (HMOX1) 83.9
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 81.0
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 75.1
 LDTP03540  Heme oxygenase 2 (HMOX2) 70.0
 LDTP06511  Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETFDH) 67.6
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 58.5
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 58.5
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 57.3
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 56.5
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 55.3
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 54.9
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 51.3
 LDTP03671  Multidrug resistance-associated protein 1 (ABCC1) 51.3
 LDTP11127  ADP-dependent glucokinase (ADPGK) 50.2
 LDTP05476  3-ketodihydrosphingosine reductase (KDSR) 48.2
 LDTP15328  Dolichyldiphosphatase 1 (DOLPP1) 46.9
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 46.9
 LDTP16025  Ketosamine-3-kinase (FN3KRP) 45.3
 LDTP14276  NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) 45.3
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 44.6
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1) 44.6
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 43.4
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 42.8
 LDTP12639  1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) 42.2
 LDTP01335  Protein SCO1 homolog, mitochondrial (SCO1) 42.2
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 42.2
 LDTP19745  ADP-ribosylation factor-like protein 10 (ARL10) 41.1
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 40.8
 LDTP08728  Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) 40.8
 LDTP10329  Ceramide synthase 2 (CERS2) 40.2
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1) 40.2
 LDTP10699  E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) 39.9
 LDTP06325  3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) 38.3
 LDTP03145  Catechol O-methyltransferase (COMT) 37.8
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 37.5
 LDTP08799  Lysophosphatidylserine lipase ABHD12 (ABHD12) 37.5
 LDTP09396  Minor histocompatibility antigen H13 (HM13) 37.3
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 36.5
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 35.8
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 35.8
 LDTP02486  Lysosomal alpha-glucosidase (GAA) 35.8
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 35.5
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 35.5
 LDTP14264  Choline/ethanolaminephosphotransferase 1 (CEPT1) 35.0
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 34.5
 LDTP14218  Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) 34.5
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 34.1
 LDTP01773  Cytochrome c oxidase subunit 2 (MT-CO2) 33.4
 LDTP12720  Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) 33.4
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 33.4
 LDTP06638  Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2) 33.1
 LDTP05905  Acid ceramidase (ASAH1) 32.2
 LDTP09188  Lysophosphatidylcholine acyltransferase 1 (LPCAT1) 31.8
 LDTP08790  Mitochondrial cardiolipin hydrolase (PLD6) 31.8
 LDTP01300  Cartilage-associated protein (CRTAP) 31.6
 LDTP12886  Glycerophosphodiester phosphodiesterase 1 (GDE1) 31.3
 LDTP14030  V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) 31.3
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 30.7
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 30.3
 LDTP02000  3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) 30.1
 LDTP10188  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) 30.1
 LDTP10020  Ras-related protein Rab-24 (RAB24) 29.9
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 29.9
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 29.2
 LDTP07227  Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) 29.2
 LDTP12490  Sphingosine kinase 2 (SPHK2) 28.8
 LDTP11867  UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) 28.8
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 28.6
 LDTP03779  Copper-transporting ATPase 2 (ATP7B) 28.4
 LDTP00950  Dynamin-like 120 kDa protein, mitochondrial (OPA1) 28.2
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 27.9
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) 27.7
 LDTP02539  Lysosomal acid phosphatase (ACP2) 27.7
 LDTP10780  Trimethylguanosine synthase (TGS1) 27.7
 LDTP19851  Isochorismatase domain-containing protein 1 (ISOC1) 27.5
 LDTP09251  Atlastin-2 (ATL2) 27.3
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 27.3
 LDTP09256  Putative phospholipase B-like 2 (PLBD2) 27.3
 LDTP03854  Vitamin K-dependent gamma-carboxylase (GGCX) 27.3
 LDTP04634  Alpha-N-acetylglucosaminidase (NAGLU) 27.1
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 27.1
 LDTP08530  Mitofusin-1 (MFN1) 26.9
 LDTP13220  Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) 26.2
 LDTP06142  Squalene monooxygenase (SQLE) 26.2
 LDTP03900  ADP-ribosylation factor-like protein 1 (ARL1) 25.8
 LDTP16040  Glyoxalase domain-containing protein 4 (GLOD4) 25.8
 LDTP12763  Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) 25.8
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 25.6
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 25.6
 LDTP07154  ATPase family AAA domain-containing protein 3B (ATAD3B) 25.5
 LDTP10471  Protein disulfide-isomerase TMX3 (TMX3) 25.5
 LDTP04581  Holocytochrome c-type synthase (HCCS) 25.3
 LDTP05228  Calcium-transporting ATPase type 2C member 1 (ATP2C1) 24.9
 LDTP12253  Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) 24.8
 LDTP08265  N-alpha-acetyltransferase 40 (NAA40) 24.4
 LDTP05408  Antigen peptide transporter 1 (TAP1) 23.9
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 23.9
 LDTP15988  Probable serine carboxypeptidase CPVL (CPVL) 23.9
 LDTP00032  2-hydroxyacyl-CoA lyase 2 (ILVBL) 23.4
 LDTP02505  Lysosomal protective protein (CTSA) 23.1
 LDTP04333  GMP synthase [glutamine-hydrolyzing] (GMPS) 22.8
 LDTP12470  GTP-binding protein SAR1a (SAR1A) 22.8
 LDTP13620  Lysosomal thioesterase PPT2 (PPT2) 22.8
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 22.8
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 22.8
 LDTP08177  Dehydrodolichyl diphosphate synthase complex subunit DHDDS (DHDDS) 22.6
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 22.6
 LDTP09874  Endoplasmic reticulum protein SC65 (P3H4) 22.6
 LDTP04531  Hexokinase-2 (HK2) 22.6
 LDTP01743  NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) 22.6
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) 22.6
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) 22.5
 LDTP12954  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) 22.3
 LDTP06618  ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) 22.2
 LDTP13486  Long-chain-fatty-acid--CoA ligase 6 (ACSL6) 22.2
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 22.2
 LDTP03103  Glutathione S-transferase Mu 3 (GSTM3) 21.9
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 21.9
 LDTP06721  GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) 21.7
 LDTP02896  Sphingomyelin phosphodiesterase (SMPD1) 21.7
 LDTP02188  Protein disulfide-isomerase (P4HB) 21.6
 LDTP13986  Vesicle transport protein GOT1B (GOLT1B) 21.3
 LDTP01803  Adenosine deaminase (ADA) 21.1
 LDTP01649  Phosphatidate cytidylyltransferase 2 (CDS2) 21.1
 LDTP10530  Beta-1,3-galactosyltransferase 6 (B3GALT6) 21.0
 LDTP12608  Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) 21.0
 LDTP10966  Microsomal glutathione S-transferase 2 (MGST2) 20.8
 LDTP02679  Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) 20.8
 LDTP12180  Retinol dehydrogenase 14 (RDH14) 20.8
 LDTP09395  Signal peptide peptidase-like 2A (SPPL2A) 20.8
 LDTP12868  Endoplasmic reticulum aminopeptidase 1 (ERAP1) 20.7
 LDTP03198  Ferrochelatase, mitochondrial (FECH) 20.7
 LDTP02550  Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (DBT) 20.7
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 20.5
 LDTP01465  Glutaminase kidney isoform, mitochondrial (GLS) 20.5
 LDTP12105  L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH) 20.5
 LDTP00597  Serine palmitoyltransferase 1 (SPTLC1) 20.5
 LDTP06905  Acylglycerol kinase, mitochondrial (AGK) 20.3
 LDTP09814  Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) 20.1
 LDTP04008  Endothelin-converting enzyme 1 (ECE1) 20.1
 LDTP01514  NADH dehydrogenase 1 beta subcomplex subunit 4 (NDUFB4) 20.1
 LDTP07868  Protein O-mannosyl-transferase TMTC3 (TMTC3) 20.1
Transporter and channel
Click to Show/Hide to Show 125 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15648  BRI3-binding protein (BRI3BP) 99.7
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 99.7
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 99.7
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 99.7
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 99.7
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 95.0
 LDTP05900  Metaxin-1 (MTX1) 87.4
 LDTP01671  STARD3 N-terminal-like protein (STARD3NL) 79.9
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 75.6
 LDTP12383  Protein GPR108 (GPR108) 71.0
 LDTP02608  ADP/ATP translocase 1 (SLC25A4) 70.0
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 70.0
 LDTP08881  Transmembrane protein 199 (TMEM199) 62.7
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 57.7
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 56.1
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 53.4
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 53.1
 LDTP10669  Melanoma inhibitory activity protein 2 (MIA2) 52.7
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 51.6
 LDTP13164  Protein sel-1 homolog 1 (SEL1L) 51.6
 LDTP16813  Tetraspanin-3 (TSPAN3) 50.2
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 48.2
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 47.5
 LDTP08016  Proton-coupled amino acid transporter 1 (SLC36A1) 47.2
 LDTP02215  Prosaposin (PSAP) 45.6
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 45.3
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 43.7
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 41.1
 LDTP11250  MICOS complex subunit MIC26 (APOO) 40.8
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 40.2
 LDTP18153  Major facilitator superfamily domain-containing protein 3 (MFSD3) 39.9
 LDTP11615  Protein tweety homolog 3 (TTYH3) 39.9
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 39.4
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 39.4
 LDTP10065  Transmembrane protein 230 (TMEM230) 39.1
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 38.3
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 38.3
 LDTP01455  Erlin-2 (ERLIN2) 38.1
 LDTP04237  Protein ERGIC-53 (LMAN1) 38.1
 LDTP11245  Derlin-1 (DERL1) 37.3
 LDTP04789  Synaptojanin-2-binding protein (SYNJ2BP) 37.3
 LDTP10663  Importin-9 (IPO9) 37.0
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 36.5
 LDTP15948  Transmembrane protein 126A (TMEM126A) 36.5
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 35.8
 LDTP01060  PRA1 family protein 2 (PRAF2) 35.8
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 35.3
 LDTP07236  Protein GPR107 (GPR107) 35.3
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 35.0
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 34.8
 LDTP01542  Golgi SNAP receptor complex member 1 (GOSR1) 34.3
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 33.8
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 33.6
 LDTP09294  Proton-coupled zinc antiporter SLC30A5 (SLC30A5) 33.4
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 32.7
 LDTP03064  Cytochrome c oxidase subunit 5A, mitochondrial (COX5A) 32.0
 LDTP13320  Prenylated Rab acceptor protein 1 (RABAC1) 32.0
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 31.1
 LDTP15979  Transmembrane protein 245 (TMEM245) 30.7
 LDTP01200  Peroxisomal membrane protein PEX14 (PEX14) 30.5
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 30.5
 LDTP04227  Guided entry of tail-anchored proteins factor CAMLG (CAMLG) 30.3
 LDTP01234  Erlin-1 (ERLIN1) 29.7
 LDTP16069  Peroxisomal membrane protein 2 (PXMP2) 29.7
 LDTP03559  High affinity cationic amino acid transporter 1 (SLC7A1) 29.2
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 29.2
 LDTP03380  Stomatin (STOM) 28.8
 LDTP09788  Sorting nexin-19 (SNX19) 28.6
 LDTP18459  StAR-related lipid transfer protein 7, mitochondrial (STARD7) 28.1
 LDTP15481  Transmembrane protein 87A (TMEM87A) 27.7
 LDTP07439  Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) 26.7
 LDTP03905  Peroxisomal biogenesis factor 19 (PEX19) 26.7
 LDTP04787  Transmembrane protein 33 (TMEM33) 26.7
 LDTP12331  Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) 26.5
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 26.4
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 26.2
 LDTP14717  ATP synthase subunit e, mitochondrial (ATP5ME) 26.0
 LDTP06221  StAR-related lipid transfer protein 3 (STARD3) 26.0
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 25.8
 LDTP01100  Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) 25.6
 LDTP04463  H(+)/Cl(-) exchange transporter 7 (CLCN7) 25.1
 LDTP11634  Derlin-2 (DERL2) 24.9
 LDTP10804  Chloride channel CLIC-like protein 1 (CLCC1) 24.8
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) 24.6
 LDTP14275  Sodium bicarbonate cotransporter 3 (SLC4A7) 24.6
 LDTP13943  Thioredoxin-related transmembrane protein 2 (TMX2) 24.4
 LDTP02061  Anion exchange protein 2 (SLC4A2) 23.9
 LDTP07467  Rhomboid domain-containing protein 2 (RHBDD2) 23.9
 LDTP07058  Transmembrane protein 201 (TMEM201) 23.9
 LDTP13969  Transmembrane emp24 domain-containing protein 7 (TMED7) 23.8
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 23.6
 LDTP07531  Sideroflexin-4 (SFXN4) 23.6
 LDTP09144  Metal transporter CNNM3 (CNNM3) 23.4
 LDTP12207  Putative divalent cation/proton antiporter TMEM165 (TMEM165) 23.3
 LDTP11213  Nucleoporin NDC1 (NDC1) 22.9
 LDTP00592  Surfeit locus protein 4 (SURF4) 22.9
 LDTP01217  Metaxin-2 (MTX2) 22.8
 LDTP01748  Mitochondrial import receptor subunit TOM40 homolog (TOMM40) 22.8
 LDTP07477  Transmembrane protein 214 (TMEM214) 22.8
 LDTP09459  Volume-regulated anion channel subunit LRRC8C (LRRC8C) 22.8
 LDTP13393  Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) 22.5
 LDTP10317  THO complex subunit 1 (THOC1) 22.5
 LDTP09288  Vang-like protein 1 (VANGL1) 22.5
 LDTP00547  Secretory carrier-associated membrane protein 2 (SCAMP2) 22.3
 LDTP00310  Syntenin-1 (SDCBP) 22.3
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 22.2
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 22.2
 LDTP01380  Wolframin (WFS1) 22.0
 LDTP03405  Calnexin (CANX) 21.9
 LDTP10398  Receptor expression-enhancing protein 6 (REEP6) 21.7
 LDTP02562  Lysosome-associated membrane glycoprotein 1 (LAMP1) 21.6
 LDTP09333  Golgin subfamily A member 5 (GOLGA5) 21.4
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 21.4
 LDTP12979  Transmembrane protein 14C (TMEM14C) 21.3
 LDTP07667  Transmembrane protein 205 (TMEM205) 21.3
 LDTP07537  Metal transporter CNNM4 (CNNM4) 21.1
 LDTP12725  Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUB) 21.0
 LDTP11732  Magnesium transporter protein 1 (MAGT1) 21.0
 LDTP08315  THO complex subunit 6 homolog (THOC6) 21.0
 LDTP08981  Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) 20.8
 LDTP12451  Integral membrane protein 2C (ITM2C) 20.8
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 20.8
 LDTP06293  Metal cation symporter ZIP14 (SLC39A14) 20.5
 LDTP13953  Endophilin-B1 (SH3GLB1) 20.4
 LDTP11406  Transmembrane protein 59 (TMEM59) 20.3
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 42.2
Immunoglobulin
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05572  Leukocyte surface antigen CD47 (CD47) 30.3
 LDTP03772  Basigin (BSG) 26.5
Other
Click to Show/Hide to Show 102 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11076  Apolipoprotein L2 (APOL2) 99.7
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 99.7
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 99.7
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 99.7
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 99.7
 LDTP18883  Protein CEBPZOS (CEBPZOS) 99.7
 LDTP01522  Reticulon-3 (RTN3) 99.7
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 86.2
 LDTP18569  PRELI domain containing protein 3B (PRELID3B) 75.6
 LDTP12412  Reticulon-4 (RTN4) 72.0
 LDTP05160  Nucleobindin-2 (NUCB2) 70.5
 LDTP10056  Protein FAM162A (FAM162A) 67.2
 LDTP05375  Nucleobindin-1 (NUCB1) 64.4
 LDTP13086  Syntaxin-18 (STX18) 62.2
 LDTP08154  Large ribosomal subunit protein uL10m (MRPL10) 58.5
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 55.7
 LDTP15944  Cytochrome c oxidase assembly factor 1 homolog (COA1) 54.2
 LDTP16080  Protein FAM114A2 (FAM114A2) 53.4
 LDTP19780  Keratinocyte-associated transmembrane protein 2 (KCT2) 53.1
 LDTP09773  Protein FAM3C (FAM3C) 53.1
 LDTP15067  Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) 45.6
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 44.3
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 43.7
 LDTP01167  Reticulon-2 (RTN2) 43.4
 LDTP14458  Tetraspanin-6 (TSPAN6) 43.4
 LDTP11143  Centromere protein K (CENPK) 43.1
 LDTP13451  DCC-interacting protein 13-alpha (APPL1) 42.5
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 42.2
 LDTP15095  Receptor expression-enhancing protein 3 (REEP3) 41.6
 LDTP00859  Synaptogyrin-2 (SYNGR2) 40.5
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 40.2
 LDTP19963  TraB domain-containing protein (TRABD) 39.9
 LDTP08224  Protein LYRIC (MTDH) 39.7
 LDTP15398  Protein FAM177A1 (FAM177A1) 38.1
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 37.3
 LDTP13606  Mammalian ependymin-related protein 1 (EPDR1) 37.0
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 36.0
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 35.5
 LDTP13807  PRELI domain-containing protein 1, mitochondrial (PRELID1) 35.0
 LDTP01494  Protein YIF1A (YIF1A) 35.0
 LDTP06948  Protein YIF1B (YIF1B) 34.5
 LDTP10775  Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) 33.6
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 33.6
 LDTP11911  Golgi phosphoprotein 3 (GOLPH3) 33.1
 LDTP08606  Nurim (NRM) 33.1
 LDTP00986  Syntaxin-10 (STX10) 32.7
 LDTP07891  Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) 31.3
 LDTP03352  Splicing factor U2AF 65 kDa subunit (U2AF2) 30.5
 LDTP15240  LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) 29.9
 LDTP16322  Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) 29.9
 LDTP13519  Proteasome activator complex subunit 2 (PSME2) 29.9
 LDTP05715  Vesicle transport protein SEC20 (BNIP1) 29.9
 LDTP19021  EF-hand calcium-binding domain-containing protein 14 (EFCAB14) 29.0
 LDTP06097  Reticulocalbin-2 (RCN2) 28.8
 LDTP04684  Nucleosome assembly protein 1-like 1 (NAP1L1) 28.4
 LDTP01358  Pre-mRNA-splicing factor SPF27 (BCAS2) 28.1
 LDTP05530  Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) 27.9
 LDTP04356  Emerin (EMD) 27.7
 LDTP00779  Trans-Golgi network integral membrane protein 2 (TGOLN2) 27.7
 LDTP03729  General transcription factor IIF subunit 1 (GTF2F1) 27.5
 LDTP11167  Protein YIPF4 (YIPF4) 27.3
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 27.1
 LDTP16285  Transducin beta-like protein 2 (TBL2) 27.1
 LDTP09787  Nicastrin (NCSTN) 26.9
 LDTP13802  DNA replication complex GINS protein PSF2 (GINS2) 26.4
 LDTP13412  Anaphase-promoting complex subunit 2 (ANAPC2) 25.8
 LDTP12982  Mitochondrial import receptor subunit TOM7 homolog (TOMM7) 25.8
 LDTP19005  SLC35A4 upstream open reading frame protein (SLC35A4) 25.8
 LDTP09324  Ganglioside-induced differentiation-associated protein 1 (GDAP1) 25.3
 LDTP18272  Transmembrane protein 209 (TMEM209) 25.1
 LDTP04703  Tumor protein D52 (TPD52) 24.6
 LDTP13755  Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) 24.4
 LDTP02927  Ganglioside GM2 activator (GM2A) 24.4
 LDTP13967  Transmembrane emp24 domain-containing protein 5 (TMED5) 24.4
 LDTP13664  Syntaxin-8 (STX8) 24.3
 LDTP12642  CYFIP-related Rac1 interactor B (CYRIB) 24.1
 LDTP07916  Protein MTSS 2 (MTSS2) 24.1
 LDTP07718  MICOS complex subunit MIC27 (APOOL) 23.8
 LDTP06291  ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) 23.1
 LDTP11326  FUN14 domain-containing protein 2 (FUNDC2) 22.9
 LDTP10965  Nucleosome assembly protein 1-like 4 (NAP1L4) 22.9
 LDTP09589  Charged multivesicular body protein 7 (CHMP7) 22.8
 LDTP17003  Matrix-remodeling-associated protein 7 (MXRA7) 22.5
 LDTP04425  Translocon-associated protein subunit delta (SSR4) 22.3
 LDTP13125  Protein UXT (UXT) 22.2
 LDTP14080  U6 snRNA-associated Sm-like protein LSm5 (LSM5) 22.2
 LDTP04626  UV excision repair protein RAD23 homolog A (RAD23A) 22.2
 LDTP12468  Diablo IAP-binding mitochondrial protein (DIABLO) 22.0
 LDTP08689  Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) 22.0
 LDTP02297  Vimentin (VIM) 22.0
 LDTP08420  BLOC-2 complex member HPS6 (HPS6) 21.9
 LDTP03425  Tropomodulin-1 (TMOD1) 21.9
 LDTP04207  Heat shock 70 kDa protein 13 (HSPA13) 21.7
 LDTP05277  Protein SET (SET) 21.7
 LDTP08364  Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) 21.4
 LDTP11978  HAUS augmin-like complex subunit 4 (HAUS4) 21.3
 LDTP07598  BRCA1-associated ATM activator 1 (BRAT1) 21.1
 LDTP09679  Negative elongation factor B (NELFB) 20.7
 LDTP04980  U6 snRNA-associated Sm-like protein LSm6 (LSM6) 20.7
 LDTP11981  Receptor expression-enhancing protein 4 (REEP4) 20.4
 LDTP10703  Leukocyte receptor cluster member 8 (LENG8) 20.3
 LDTP01206  Vesicle-trafficking protein SEC22b (SEC22B) 20.1

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587