Details of the Target

General Information of Target

Target ID LDTP00547
Target Name Secretory carrier-associated membrane protein 2 (SCAMP2)
Gene Name SCAMP2
Gene ID 10066
Synonyms
Secretory carrier-associated membrane protein 2; Secretory carrier membrane protein 2
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSAFDTNPFADPVDVNPFQDPSVTQLTNAPQGGLAEFNPFSETNAATTVPVTQLPGSSQP
AVLQPSVEPTQPTPQAVVSAAQAGLLRQQEELDRKAAELERKERELQNTVANLHVRQNNW
PPLPSWCPVKPCFYQDFSTEIPADYQRICKMLYYLWMLHSVTLFLNLLACLAWFSGNSSK
GVDFGLSILWFLIFTPCAFLCWYRPIYKAFRSDNSFSFFVFFFVFFCQIGIYIIQLVGIP
GLGDSGWIAALSTLDNHSLAISVIMMVVAGFFTLCAVLSVFLLQRVHSLYRRTGASFQQA
QEEFSQGIFSSRTFHRAASSAAQGAFQGN
Target Bioclass
Transporter and channel
Family
SCAMP family
Subcellular location
Golgi apparatus, trans-Golgi network membrane
Function Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.
Uniprot ID
O15127
Ensemble ID
ENST00000268099.13
HGNC ID
HGNC:10564

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 7 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
YN-1
 Probe Info  		100.00  LDD0444  [1]
AZ-9
 Probe Info  		E303(10.00)  LDD2209  [2]
HPAP
 Probe Info  		4.01  LDD0062  [3]
Acrolein
 Probe Info  		N.A.  LDD0227  [4]
DBIA
 Probe Info  		C127(1.24)  LDD0563  [5]
CY-1
 Probe Info  		Q323(0.00); Q327(0.00)  LDD0246  [6]
AOyne
 Probe Info  		7.10  LDD0443  [7]
PAL-AfBPP Probe
Click To Hide/Show 60 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C004
 Probe Info  		10.13  LDD1714  [8]
C022
 Probe Info  		15.45  LDD1728  [8]
C040
 Probe Info  		7.06  LDD1740  [8]
C055
 Probe Info  		12.38  LDD1752  [8]
C056
 Probe Info  		19.97  LDD1753  [8]
C063
 Probe Info  		10.63  LDD1760  [8]
C070
 Probe Info  		14.03  LDD1766  [8]
C106
 Probe Info  		33.36  LDD1793  [8]
C107
 Probe Info  		6.59  LDD1794  [8]
C108
 Probe Info  		14.22  LDD1795  [8]
C112
 Probe Info  		19.97  LDD1799  [8]
C134
 Probe Info  		22.32  LDD1816  [8]
C141
 Probe Info  		14.22  LDD1823  [8]
C143
 Probe Info  		26.72  LDD1825  [8]
C153
 Probe Info  		50.56  LDD1834  [8]
C159
 Probe Info  		9.65  LDD1839  [8]
C161
 Probe Info  		14.12  LDD1841  [8]
C163
 Probe Info  		17.51  LDD1843  [8]
C165
 Probe Info  		16.91  LDD1845  [8]
C178
 Probe Info  		52.71  LDD1857  [8]
C186
 Probe Info  		14.12  LDD1864  [8]
C187
 Probe Info  		65.34  LDD1865  [8]
C193
 Probe Info  		6.23  LDD1869  [8]
C194
 Probe Info  		11.31  LDD1870  [8]
C198
 Probe Info  		10.70  LDD1874  [8]
C201
 Probe Info  		99.73  LDD1877  [8]
C206
 Probe Info  		43.11  LDD1881  [8]
C207
 Probe Info  		23.26  LDD1882  [8]
C211
 Probe Info  		8.11  LDD1885  [8]
C218
 Probe Info  		11.47  LDD1892  [8]
C219
 Probe Info  		5.43  LDD1893  [8]
C220
 Probe Info  		32.90  LDD1894  [8]
C273
 Probe Info  		5.13  LDD1943  [8]
C277
 Probe Info  		19.03  LDD1947  [8]
C293
 Probe Info  		37.53  LDD1963  [8]
C296
 Probe Info  		41.36  LDD1966  [8]
C299
 Probe Info  		6.82  LDD1968  [8]
C307
 Probe Info  		6.23  LDD1975  [8]
C310
 Probe Info  		16.11  LDD1977  [8]
C314
 Probe Info  		17.51  LDD1981  [8]
C326
 Probe Info  		27.67  LDD1990  [8]
C339
 Probe Info  		7.78  LDD2002  [8]
C343
 Probe Info  		21.26  LDD2005  [8]
C348
 Probe Info  		10.48  LDD2009  [8]
C349
 Probe Info  		11.39  LDD2010  [8]
C350
 Probe Info  		77.17  LDD2011  [8]
C356
 Probe Info  		9.06  LDD2017  [8]
C362
 Probe Info  		49.52  LDD2023  [8]
C363
 Probe Info  		23.10  LDD2024  [8]
C364
 Probe Info  		20.11  LDD2025  [8]
C376
 Probe Info  		16.56  LDD2036  [8]
C378
 Probe Info  		10.93  LDD2037  [8]
C383
 Probe Info  		10.93  LDD2042  [8]
C386
 Probe Info  		7.73  LDD2045  [8]
C388
 Probe Info  		37.79  LDD2047  [8]
C390
 Probe Info  		95.01  LDD2049  [8]
C413
 Probe Info  		13.74  LDD2069  [8]
C431
 Probe Info  		13.64  LDD2086  [8]
VE-P
 Probe Info  		N.A.  LDD0396  [9]
OEA-DA
 Probe Info  		16.91  LDD0046  [10]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0214  AC1 HEK-293T C132(1.04); C127(0.99)  LDD1507  [11]
 LDCM0215  AC10 HEK-293T C132(1.10); C127(0.87)  LDD1508  [11]
 LDCM0226  AC11 HEK-293T C132(1.05); C127(1.06)  LDD1509  [11]
 LDCM0237  AC12 HEK-293T C132(1.26); C127(1.04)  LDD1510  [11]
 LDCM0246  AC128 HCT 116 C127(1.24)  LDD0563  [5]
 LDCM0247  AC129 HCT 116 C127(1.34)  LDD0564  [5]
 LDCM0249  AC130 HCT 116 C127(1.10)  LDD0566  [5]
 LDCM0250  AC131 HCT 116 C127(1.24)  LDD0567  [5]
 LDCM0251  AC132 HCT 116 C127(1.24)  LDD0568  [5]
 LDCM0252  AC133 HCT 116 C127(1.20)  LDD0569  [5]
 LDCM0253  AC134 HCT 116 C127(1.31)  LDD0570  [5]
 LDCM0254  AC135 HCT 116 C127(1.05)  LDD0571  [5]
 LDCM0255  AC136 HCT 116 C127(1.19)  LDD0572  [5]
 LDCM0256  AC137 HCT 116 C127(1.08)  LDD0573  [5]
 LDCM0257  AC138 HCT 116 C127(1.01)  LDD0574  [5]
 LDCM0258  AC139 HCT 116 C127(1.29)  LDD0575  [5]
 LDCM0259  AC14 HEK-293T C132(0.96); C127(0.95)  LDD1512  [11]
 LDCM0260  AC140 HCT 116 C127(1.19)  LDD0577  [5]
 LDCM0261  AC141 HCT 116 C127(1.21)  LDD0578  [5]
 LDCM0262  AC142 HCT 116 C127(1.07)  LDD0579  [5]
 LDCM0263  AC143 HCT 116 C127(1.02)  LDD0580  [5]
 LDCM0264  AC144 HCT 116 C127(1.07)  LDD0581  [5]
 LDCM0265  AC145 HCT 116 C127(1.06)  LDD0582  [5]
 LDCM0266  AC146 HCT 116 C127(1.39)  LDD0583  [5]
 LDCM0267  AC147 HCT 116 C127(1.14)  LDD0584  [5]
 LDCM0268  AC148 HCT 116 C127(1.64)  LDD0585  [5]
 LDCM0269  AC149 HCT 116 C127(1.41)  LDD0586  [5]
 LDCM0270  AC15 HEK-293T C132(1.20); C127(0.98)  LDD1513  [11]
 LDCM0271  AC150 HCT 116 C127(1.27)  LDD0588  [5]
 LDCM0272  AC151 HCT 116 C127(1.09)  LDD0589  [5]
 LDCM0273  AC152 HCT 116 C127(0.99)  LDD0590  [5]
 LDCM0274  AC153 HCT 116 C127(1.22)  LDD0591  [5]
 LDCM0621  AC154 HCT 116 C127(1.00)  LDD2158  [5]
 LDCM0622  AC155 HCT 116 C127(1.04)  LDD2159  [5]
 LDCM0623  AC156 HCT 116 C127(1.10)  LDD2160  [5]
 LDCM0624  AC157 HCT 116 C127(1.05)  LDD2161  [5]
 LDCM0276  AC17 HEK-293T C132(1.00); C127(1.07)  LDD1515  [11]
 LDCM0277  AC18 HEK-293T C132(1.10); C127(0.95)  LDD1516  [11]
 LDCM0278  AC19 HEK-293T C132(1.14); C127(1.15)  LDD1517  [11]
 LDCM0279  AC2 HEK-293T C132(1.00); C127(0.96)  LDD1518  [11]
 LDCM0280  AC20 HEK-293T C132(1.02); C127(0.98)  LDD1519  [11]
 LDCM0281  AC21 HEK-293T C132(1.13); C127(1.21)  LDD1520  [11]
 LDCM0282  AC22 HEK-293T C132(0.99); C127(1.05)  LDD1521  [11]
 LDCM0283  AC23 HEK-293T C132(1.21); C127(0.85)  LDD1522  [11]
 LDCM0284  AC24 HEK-293T C132(0.97); C127(0.92)  LDD1523  [11]
 LDCM0285  AC25 HEK-293T C132(0.98); C127(0.92)  LDD1524  [11]
 LDCM0286  AC26 HEK-293T C132(1.10); C127(0.82)  LDD1525  [11]
 LDCM0287  AC27 HEK-293T C132(0.99); C127(0.96)  LDD1526  [11]
 LDCM0288  AC28 HEK-293T C132(1.02); C127(1.00)  LDD1527  [11]
 LDCM0289  AC29 HEK-293T C132(1.00); C127(1.03)  LDD1528  [11]
 LDCM0290  AC3 HEK-293T C132(1.00); C127(1.03)  LDD1529  [11]
 LDCM0291  AC30 HEK-293T C132(0.92); C127(0.91)  LDD1530  [11]
 LDCM0292  AC31 HEK-293T C132(1.14); C127(0.87)  LDD1531  [11]
 LDCM0293  AC32 HEK-293T C132(0.96); C127(0.84)  LDD1532  [11]
 LDCM0294  AC33 HEK-293T C132(1.10); C127(1.06)  LDD1533  [11]
 LDCM0295  AC34 HEK-293T C132(1.04); C127(0.89)  LDD1534  [11]
 LDCM0296  AC35 HEK-293T C132(1.14); C127(1.08)  LDD1535  [11]
 LDCM0297  AC36 HEK-293T C132(1.01); C127(0.94)  LDD1536  [11]
 LDCM0298  AC37 HEK-293T C132(0.93); C127(1.03)  LDD1537  [11]
 LDCM0299  AC38 HEK-293T C132(1.09); C127(1.04)  LDD1538  [11]
 LDCM0300  AC39 HEK-293T C132(1.19); C127(0.85)  LDD1539  [11]
 LDCM0301  AC4 HEK-293T C132(1.11); C127(0.98)  LDD1540  [11]
 LDCM0302  AC40 HEK-293T C132(1.04); C127(0.94)  LDD1541  [11]
 LDCM0303  AC41 HEK-293T C132(1.07); C127(1.02)  LDD1542  [11]
 LDCM0304  AC42 HEK-293T C132(1.11); C127(0.95)  LDD1543  [11]
 LDCM0305  AC43 HEK-293T C132(1.21); C127(1.00)  LDD1544  [11]
 LDCM0306  AC44 HEK-293T C132(1.03); C127(0.97)  LDD1545  [11]
 LDCM0307  AC45 HEK-293T C132(1.05); C127(1.03)  LDD1546  [11]
 LDCM0308  AC46 HCT 116 C127(1.44)  LDD0625  [5]
 LDCM0309  AC47 HCT 116 C127(0.99)  LDD0626  [5]
 LDCM0310  AC48 HCT 116 C127(0.99)  LDD0627  [5]
 LDCM0311  AC49 HCT 116 C127(1.11)  LDD0628  [5]
 LDCM0312  AC5 HEK-293T C132(0.99); C127(0.98)  LDD1551  [11]
 LDCM0313  AC50 HCT 116 C127(1.16)  LDD0630  [5]
 LDCM0314  AC51 HCT 116 C127(0.80)  LDD0631  [5]
 LDCM0315  AC52 HCT 116 C127(0.97)  LDD0632  [5]
 LDCM0316  AC53 HCT 116 C127(0.94)  LDD0633  [5]
 LDCM0317  AC54 HCT 116 C127(1.20)  LDD0634  [5]
 LDCM0318  AC55 HCT 116 C127(1.19)  LDD0635  [5]
 LDCM0319  AC56 HCT 116 C127(0.76)  LDD0636  [5]
 LDCM0320  AC57 HEK-293T C132(1.12); C127(1.17)  LDD1559  [11]
 LDCM0321  AC58 HEK-293T C132(0.96); C127(0.96)  LDD1560  [11]
 LDCM0322  AC59 HEK-293T C132(1.02); C127(1.08)  LDD1561  [11]
 LDCM0323  AC6 HEK-293T C132(0.89); C127(0.97)  LDD1562  [11]
 LDCM0324  AC60 HEK-293T C132(1.05); C127(1.20)  LDD1563  [11]
 LDCM0325  AC61 HEK-293T C132(0.95); C127(1.18)  LDD1564  [11]
 LDCM0326  AC62 HEK-293T C132(0.97); C127(1.05)  LDD1565  [11]
 LDCM0327  AC63 HEK-293T C132(1.07); C127(1.07)  LDD1566  [11]
 LDCM0328  AC64 HEK-293T C132(0.92); C127(1.06)  LDD1567  [11]
 LDCM0334  AC7 HEK-293T C132(1.10); C127(0.85)  LDD1568  [11]
 LDCM0345  AC8 HEK-293T C132(1.01); C127(1.03)  LDD1569  [11]
 LDCM0248  AKOS034007472 HEK-293T C132(1.06); C127(1.10)  LDD1511  [11]
 LDCM0356  AKOS034007680 HEK-293T C132(1.03); C127(1.12)  LDD1570  [11]
 LDCM0275  AKOS034007705 HEK-293T C132(1.06); C127(1.07)  LDD1514  [11]
 LDCM0367  CL1 HEK-293T C132(1.13); C127(1.49)  LDD1571  [11]
 LDCM0368  CL10 HEK-293T C132(1.67); C127(2.08)  LDD1572  [11]
 LDCM0369  CL100 HEK-293T C132(1.13); C127(1.12)  LDD1573  [11]
 LDCM0370  CL101 HEK-293T C132(1.03); C127(1.15)  LDD1574  [11]
 LDCM0371  CL102 HEK-293T C132(1.18); C127(1.76)  LDD1575  [11]
 LDCM0372  CL103 HEK-293T C132(1.19); C127(1.03)  LDD1576  [11]
 LDCM0373  CL104 HEK-293T C132(1.11); C127(1.10)  LDD1577  [11]
 LDCM0374  CL105 HEK-293T C132(0.99); C127(1.19)  LDD1578  [11]
 LDCM0375  CL106 HEK-293T C132(1.07); C127(1.34)  LDD1579  [11]
 LDCM0376  CL107 HEK-293T C132(1.18); C127(0.98)  LDD1580  [11]
 LDCM0377  CL108 HEK-293T C132(1.25); C127(0.93)  LDD1581  [11]
 LDCM0378  CL109 HEK-293T C132(1.11); C127(1.24)  LDD1582  [11]
 LDCM0379  CL11 HEK-293T C132(1.64); C127(1.49)  LDD1583  [11]
 LDCM0380  CL110 HEK-293T C132(1.20); C127(2.31)  LDD1584  [11]
 LDCM0381  CL111 HEK-293T C132(1.32); C127(1.56)  LDD1585  [11]
 LDCM0382  CL112 HEK-293T C132(1.13); C127(0.93)  LDD1586  [11]
 LDCM0383  CL113 HEK-293T C132(1.04); C127(1.09)  LDD1587  [11]
 LDCM0384  CL114 HEK-293T C132(1.22); C127(1.50)  LDD1588  [11]
 LDCM0385  CL115 HEK-293T C132(1.09); C127(0.93)  LDD1589  [11]
 LDCM0386  CL116 HEK-293T C132(1.10); C127(0.97)  LDD1590  [11]
 LDCM0387  CL117 HEK-293T C132(1.09); C127(1.04)  LDD1591  [11]
 LDCM0388  CL118 HEK-293T C132(0.92); C127(0.94)  LDD1592  [11]
 LDCM0389  CL119 HEK-293T C132(1.04); C127(0.95)  LDD1593  [11]
 LDCM0390  CL12 HEK-293T C132(1.40); C127(1.43)  LDD1594  [11]
 LDCM0391  CL120 HEK-293T C132(1.14); C127(0.94)  LDD1595  [11]
 LDCM0392  CL121 HCT 116 C127(1.02)  LDD0709  [5]
 LDCM0393  CL122 HCT 116 C127(0.78)  LDD0710  [5]
 LDCM0394  CL123 HCT 116 C127(1.17)  LDD0711  [5]
 LDCM0395  CL124 HCT 116 C127(1.04)  LDD0712  [5]
 LDCM0396  CL125 HEK-293T C132(1.14); C127(1.16)  LDD1600  [11]
 LDCM0397  CL126 HEK-293T C132(1.13); C127(1.30)  LDD1601  [11]
 LDCM0398  CL127 HEK-293T C132(1.10); C127(0.97)  LDD1602  [11]
 LDCM0399  CL128 HEK-293T C132(1.07); C127(1.01)  LDD1603  [11]
 LDCM0400  CL13 HEK-293T C132(1.05); C127(1.33)  LDD1604  [11]
 LDCM0401  CL14 HEK-293T C132(1.06); C127(1.23)  LDD1605  [11]
 LDCM0402  CL15 HEK-293T C132(1.37); C127(3.45)  LDD1606  [11]
 LDCM0403  CL16 HCT 116 C127(1.01)  LDD0720  [5]
 LDCM0404  CL17 HEK-293T C132(1.31); C127(3.24)  LDD1608  [11]
 LDCM0405  CL18 HEK-293T C132(1.07); C127(1.05)  LDD1609  [11]
 LDCM0406  CL19 HEK-293T C132(1.31); C127(1.21)  LDD1610  [11]
 LDCM0407  CL2 HEK-293T C132(1.00); C127(1.03)  LDD1611  [11]
 LDCM0408  CL20 HEK-293T C132(1.71); C127(1.46)  LDD1612  [11]
 LDCM0409  CL21 HEK-293T C132(2.21); C127(4.31)  LDD1613  [11]
 LDCM0410  CL22 HEK-293T C132(1.43); C127(1.35)  LDD1614  [11]
 LDCM0411  CL23 HEK-293T C132(1.69); C127(1.18)  LDD1615  [11]
 LDCM0412  CL24 HEK-293T C132(1.18); C127(1.45)  LDD1616  [11]
 LDCM0413  CL25 HEK-293T C132(1.26); C127(1.56)  LDD1617  [11]
 LDCM0414  CL26 HEK-293T C132(0.98); C127(1.09)  LDD1618  [11]
 LDCM0415  CL27 HEK-293T C132(0.98); C127(0.98)  LDD1619  [11]
 LDCM0416  CL28 HEK-293T C132(1.15); C127(1.16)  LDD1620  [11]
 LDCM0417  CL29 HEK-293T C132(1.27); C127(1.15)  LDD1621  [11]
 LDCM0418  CL3 HEK-293T C132(1.40); C127(1.25)  LDD1622  [11]
 LDCM0419  CL30 HEK-293T C132(1.04); C127(0.99)  LDD1623  [11]
 LDCM0420  CL31 HCT 116 C127(1.09)  LDD0737  [5]
 LDCM0421  CL32 HCT 116 C127(1.04)  LDD0738  [5]
 LDCM0422  CL33 HCT 116 C127(1.23)  LDD0739  [5]
 LDCM0423  CL34 HCT 116 C127(1.18)  LDD0740  [5]
 LDCM0424  CL35 HCT 116 C127(1.18)  LDD0741  [5]
 LDCM0425  CL36 HCT 116 C127(1.14)  LDD0742  [5]
 LDCM0426  CL37 HCT 116 C127(1.04)  LDD0743  [5]
 LDCM0428  CL39 HCT 116 C127(1.08)  LDD0745  [5]
 LDCM0429  CL4 HEK-293T C132(1.26); C127(1.47)  LDD1633  [11]
 LDCM0430  CL40 HCT 116 C127(1.13)  LDD0747  [5]
 LDCM0431  CL41 HCT 116 C127(1.07)  LDD0748  [5]
 LDCM0432  CL42 HCT 116 C127(1.14)  LDD0749  [5]
 LDCM0433  CL43 HCT 116 C127(1.15)  LDD0750  [5]
 LDCM0434  CL44 HCT 116 C127(1.22)  LDD0751  [5]
 LDCM0435  CL45 HCT 116 C127(1.12)  LDD0752  [5]
 LDCM0436  CL46 HEK-293T C132(1.37); C127(1.42)  LDD1640  [11]
 LDCM0437  CL47 HEK-293T C132(1.40); C127(1.04)  LDD1641  [11]
 LDCM0438  CL48 HEK-293T C132(1.30); C127(1.43)  LDD1642  [11]
 LDCM0439  CL49 HEK-293T C132(1.07); C127(1.19)  LDD1643  [11]
 LDCM0440  CL5 HEK-293T C132(1.09); C127(1.34)  LDD1644  [11]
 LDCM0441  CL50 HEK-293T C132(1.04); C127(1.46)  LDD1645  [11]
 LDCM0443  CL52 HEK-293T C132(1.08); C127(1.04)  LDD1646  [11]
 LDCM0444  CL53 HEK-293T C132(1.87); C127(2.57)  LDD1647  [11]
 LDCM0445  CL54 HEK-293T C132(1.36); C127(1.98)  LDD1648  [11]
 LDCM0446  CL55 HEK-293T C132(1.26); C127(1.38)  LDD1649  [11]
 LDCM0447  CL56 HEK-293T C132(1.23); C127(1.38)  LDD1650  [11]
 LDCM0448  CL57 HEK-293T C132(1.39); C127(2.47)  LDD1651  [11]
 LDCM0449  CL58 HEK-293T C132(1.38); C127(1.97)  LDD1652  [11]
 LDCM0450  CL59 HEK-293T C132(1.58); C127(1.23)  LDD1653  [11]
 LDCM0451  CL6 HEK-293T C132(1.68); C127(2.29)  LDD1654  [11]
 LDCM0452  CL60 HEK-293T C132(1.20); C127(1.41)  LDD1655  [11]
 LDCM0453  CL61 HEK-293T C132(0.97); C127(1.09)  LDD1656  [11]
 LDCM0454  CL62 HEK-293T C132(0.98); C127(1.13)  LDD1657  [11]
 LDCM0455  CL63 HEK-293T C132(0.92); C127(1.04)  LDD1658  [11]
 LDCM0456  CL64 HEK-293T C132(1.38); C127(1.66)  LDD1659  [11]
 LDCM0457  CL65 HEK-293T C132(1.05); C127(1.10)  LDD1660  [11]
 LDCM0458  CL66 HEK-293T C132(1.29); C127(1.14)  LDD1661  [11]
 LDCM0459  CL67 HEK-293T C132(1.17); C127(1.10)  LDD1662  [11]
 LDCM0460  CL68 HEK-293T C132(1.42); C127(1.67)  LDD1663  [11]
 LDCM0461  CL69 HEK-293T C132(1.34); C127(1.68)  LDD1664  [11]
 LDCM0462  CL7 HEK-293T C132(1.14); C127(1.44)  LDD1665  [11]
 LDCM0463  CL70 HEK-293T C132(1.32); C127(1.18)  LDD1666  [11]
 LDCM0464  CL71 HEK-293T C132(1.30); C127(1.92)  LDD1667  [11]
 LDCM0465  CL72 HEK-293T C132(1.13); C127(1.20)  LDD1668  [11]
 LDCM0466  CL73 HEK-293T C132(1.04); C127(1.35)  LDD1669  [11]
 LDCM0467  CL74 HEK-293T C132(1.06); C127(1.01)  LDD1670  [11]
 LDCM0469  CL76 HEK-293T C132(1.06); C127(1.03)  LDD1672  [11]
 LDCM0470  CL77 HEK-293T C132(1.73); C127(2.26)  LDD1673  [11]
 LDCM0471  CL78 HEK-293T C132(1.08); C127(1.00)  LDD1674  [11]
 LDCM0472  CL79 HEK-293T C132(1.09); C127(1.22)  LDD1675  [11]
 LDCM0473  CL8 HEK-293T C132(3.84); C127(5.52)  LDD1676  [11]
 LDCM0474  CL80 HEK-293T C132(1.06); C127(1.08)  LDD1677  [11]
 LDCM0475  CL81 HEK-293T C132(1.17); C127(1.37)  LDD1678  [11]
 LDCM0476  CL82 HEK-293T C132(1.18); C127(1.05)  LDD1679  [11]
 LDCM0477  CL83 HEK-293T C132(1.47); C127(1.16)  LDD1680  [11]
 LDCM0478  CL84 HEK-293T C132(1.48); C127(1.60)  LDD1681  [11]
 LDCM0479  CL85 HEK-293T C132(1.10); C127(1.18)  LDD1682  [11]
 LDCM0480  CL86 HEK-293T C132(1.26); C127(1.22)  LDD1683  [11]
 LDCM0481  CL87 HEK-293T C132(1.19); C127(1.15)  LDD1684  [11]
 LDCM0482  CL88 HEK-293T C132(1.12); C127(1.04)  LDD1685  [11]
 LDCM0483  CL89 HEK-293T C132(1.27); C127(1.18)  LDD1686  [11]
 LDCM0484  CL9 HEK-293T C132(1.40); C127(1.72)  LDD1687  [11]
 LDCM0485  CL90 HEK-293T C132(1.58); C127(3.21)  LDD1688  [11]
 LDCM0486  CL91 HEK-293T C132(1.27); C127(1.16)  LDD1689  [11]
 LDCM0487  CL92 HEK-293T C132(1.54); C127(1.49)  LDD1690  [11]
 LDCM0488  CL93 HEK-293T C132(1.09); C127(1.82)  LDD1691  [11]
 LDCM0489  CL94 HEK-293T C132(1.31); C127(1.12)  LDD1692  [11]
 LDCM0490  CL95 HEK-293T C132(3.02); C127(2.69)  LDD1693  [11]
 LDCM0491  CL96 HEK-293T C132(1.33); C127(2.24)  LDD1694  [11]
 LDCM0492  CL97 HEK-293T C132(0.92); C127(1.58)  LDD1695  [11]
 LDCM0493  CL98 HEK-293T C132(1.08); C127(1.14)  LDD1696  [11]
 LDCM0494  CL99 HEK-293T C132(0.98); C127(1.02)  LDD1697  [11]
 LDCM0495  E2913 HEK-293T C132(1.45); C127(1.12)  LDD1698  [11]
 LDCM0468  Fragment33 HEK-293T C132(1.07); C127(1.09)  LDD1671  [11]
 LDCM0427  Fragment51 HCT 116 C127(1.18)  LDD0744  [5]
 LDCM0022  KB02 HEK-293T C132(0.81); C127(0.74)  LDD1492  [11]
 LDCM0023  KB03 HEK-293T C132(1.13); C127(0.85)  LDD1497  [11]
 LDCM0024  KB05 HEK-293T C132(0.76); C127(0.60)  LDD1502  [11]
 LDCM0109  NEM HeLa N.A.  LDD0227  [4]
 LDCM0014  Panhematin HEK-293T 4.01  LDD0062  [3]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Sodium/hydrogen exchanger 7 (SLC9A7) Monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family Q96T83
Solute carrier family 41 member 1 (SLC41A1) SLC41A transporter family Q8IVJ1

References

1 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
2 2H-Azirine-Based Reagents for Chemoselective Bioconjugation at Carboxyl Residues Inside Live Cells. J Am Chem Soc. 2020 Apr 1;142(13):6051-6059. doi: 10.1021/jacs.9b12116. Epub 2020 Mar 23.
3 A Chemical Proteomic Map of Heme-Protein Interactions. J Am Chem Soc. 2022 Aug 24;144(33):15013-15019. doi: 10.1021/jacs.2c06104. Epub 2022 Aug 12.
Mass spectrometry data entry: PXD034651
4 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
5 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
6 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.
7 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
8 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
9 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
10 Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20.
Mass spectrometry data entry: PXD007570
11 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402