Details of the Probe

General Information of Probe

Probe ID
LDPC0609
Probe Name
C390
Synonyms
Z4225934471
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 322.4
Lipid-water partition coefficient (xlogp) 3.2
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C18H18N4O2
IUPAC Name
N-[2-(3-but-3-ynyldiazirin-3-yl)ethyl]-5-(4-methylphenyl)-1,3-oxazole-4-carboxamide
Canonical SMILES
CC1=CC=C(C=C1)C2=C(N=CO2)C(=O)NCCC3(N=N3)CCC#C
InChI
InChI=1S/C18H18N4O2/c1-3-4-9-18(21-22-18)10-11-19-17(23)15-16(24-12-20-15)14-7-5-13(2)6-8-14/h1,5-8,12H,4,9-11H2,2H3,(H,19,23)
InChIKey
OOQLCFOVJFZBTG-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

170 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 20.53  LDD2049 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 53.45  LDD2049 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 56.10  LDD2049 
Abasic site processing protein HMCES (HMCES) LDTP10322 25.11  LDD2049 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 49.52  LDD2049 
Acid ceramidase (ASAH1) LDTP05905 99.73  LDD2049 
Acylglycerol kinase, mitochondrial (AGK) LDTP06905 37.53  LDD2049 
Adenosine deaminase (ADA) LDTP01803 70.03  LDD2049 
ADP-dependent glucokinase (ADPGK) LDTP11127 55.33  LDD2049 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 99.73  LDD2049 
Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) LDTP03560 23.26  LDD2049 
Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) LDTP00186 21.71  LDD2049 
Alpha-1,2-mannosyltransferase ALG9 (ALG9) LDTP12002 22.01  LDD2049 
Alpha-galactosidase A (GLA) LDTP02141 39.40  LDD2049 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 48.84  LDD2049 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 23.26  LDD2049 
Atlastin-2 (ATL2) LDTP09251 37.27  LDD2049 
ATP synthase membrane subunit K, mitochondrial (ATP5MK) LDTP10432 23.92  LDD2049 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 34.06  LDD2049 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 30.06  LDD2049 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 26.17  LDD2049 
Beta-1,3-galactosyltransferase 6 (B3GALT6) LDTP10530 26.17  LDD2049 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 55.72  LDD2049 
Beta-galactosidase (GLB1) LDTP02837 49.18  LDD2049 
Beta-glucuronidase (GUSB) LDTP02260 22.32  LDD2049 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 28.44  LDD2049 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 81.01  LDD2049 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 57.28  LDD2049 
Calcium-transporting ATPase type 2C member 1 (ATP2C1) LDTP05228 25.63  LDD2049 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 86.82  LDD2049 
Carboxypeptidase D (CPD) LDTP01372 20.53  LDD2049 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 39.40  LDD2049 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 40.79  LDD2049 
Catechol O-methyltransferase (COMT) LDTP03145 57.28  LDD2049 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 99.73  LDD2049 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 45.25  LDD2049 
Choline kinase alpha (CHKA) LDTP03787 32.90  LDD2049 
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (ST3GAL4) LDTP05638 34.06  LDD2049 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 30.06  LDD2049 
Copper-transporting ATPase 1 (ATP7A) LDTP05422 20.68  LDD2049 
Copper-transporting ATPase 2 (ATP7B) LDTP03779 22.94  LDD2049 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 31.78  LDD2049 
Cytochrome b-c1 complex subunit 7 (UQCRB) LDTP02757 25.46  LDD2049 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 99.73  LDD2049 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 99.73  LDD2049 
Cytochrome b5 type B (CYB5B) LDTP00697 99.73  LDD2049 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 56.49  LDD2049 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 99.73  LDD2049 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 27.28  LDD2049 
Dehydrogenase/reductase SDR family member 7 (DHRS7) LDTP13959 21.26  LDD2049 
Delta(24)-sterol reductase (DHCR24) LDTP06375 20.53  LDD2049 
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (ECH1) LDTP05724 28.05  LDD2049 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 53.82  LDD2049 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 22.01  LDD2049 
Dihydrofolate reductase (DHFR) LDTP01769 24.42  LDD2049 
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) LDTP02362 22.32  LDD2049 
Dihydroorotate dehydrogenase (quinone), mitochondrial (DHODH) LDTP05337 26.72  LDD2049 
DNA replication licensing factor MCM6 (MCM6) LDTP06150 28.05  LDD2049 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 22.78  LDD2049 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 26.91  LDD2049 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 41.64  LDD2049 
Dual specificity protein phosphatase 9 (DUSP9) LDTP11016 29.24  LDD2049 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 31.78  LDD2049 
E3 SUMO-protein ligase NSE2 (NSMCE2) LDTP10583 25.81  LDD2049 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 23.75  LDD2049 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 22.16  LDD2049 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 24.93  LDD2049 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 41.64  LDD2049 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 56.89  LDD2049 
Epoxide hydrolase 1 (EPHX1) LDTP02175 24.76  LDD2049 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 96.34  LDD2049 
Ferrochelatase, mitochondrial (FECH) LDTP03198 75.58  LDD2049 
Geranylgeranyl pyrophosphate synthase (GGPS1) LDTP01665 42.52  LDD2049 
Glycerophosphodiester phosphodiesterase 1 (GDE1) LDTP12886 31.78  LDD2049 
Glyoxalase domain-containing protein 4 (GLOD4) LDTP16040 46.85  LDD2049 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 89.88  LDD2049 
GPI ethanolamine phosphate transferase 2 (PIGG) LDTP06977 29.86  LDD2049 
GPI-anchor transamidase (PIGK) LDTP09835 20.53  LDD2049 
Heme A synthase COX15 (COX15) LDTP07931 41.07  LDD2049 
Heme oxygenase 1 (HMOX1) LDTP02359 50.91  LDD2049 
Heme oxygenase 2 (HMOX2) LDTP03540 99.73  LDD2049 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 99.73  LDD2049 
Hexokinase-2 (HK2) LDTP04531 23.43  LDD2049 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 74.54  LDD2049 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 51.63  LDD2049 
Lathosterol oxidase (SC5D) LDTP01329 22.63  LDD2049 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 34.54  LDD2049 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 74.54  LDD2049 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 99.73  LDD2049 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 38.59  LDD2049 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 25.63  LDD2049 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 26.72  LDD2049 
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) LDTP03858 30.06  LDD2049 
Lysosomal acid phosphatase (ACP2) LDTP02539 99.73  LDD2049 
Lysosomal alpha-glucosidase (GAA) LDTP02486 21.86  LDD2049 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 97.68  LDD2049 
Lysosomal protective protein (CTSA) LDTP02505 57.28  LDD2049 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 55.72  LDD2049 
Metalloendopeptidase OMA1, mitochondrial (OMA1) LDTP10249 30.27  LDD2049 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 29.45  LDD2049 
Minor histocompatibility antigen H13 (HM13) LDTP09396 28.64  LDD2049 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 90.51  LDD2049 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 28.84  LDD2049 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 53.82  LDD2049 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 37.79  LDD2049 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 43.11  LDD2049 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 35.26  LDD2049 
NADH dehydrogenase 1 beta subcomplex subunit 4 (NDUFB4) LDTP01514 21.56  LDD2049 
NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial (NDUFB8) LDTP01515 25.46  LDD2049 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 67.65  LDD2049 
NADPH--cytochrome P450 reductase (POR) LDTP02848 25.11  LDD2049 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 30.48  LDD2049 
Oxidized purine nucleoside triphosphate hydrolase (NUDT1) LDTP03816 43.41  LDD2049 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 99.73  LDD2049 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 45.57  LDD2049 
Palmitoyltransferase ZDHHC6 (ZDHHC6) LDTP11994 25.28  LDD2049 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 20.97  LDD2049 
Peptidyl-tRNA hydrolase 2, mitochondrial (PTRH2) LDTP13989 20.82  LDD2049 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 21.41  LDD2049 
Peroxisomal trans-2-enoyl-CoA reductase (PECR) LDTP11437 23.43  LDD2049 
Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) LDTP12608 20.68  LDD2049 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 27.28  LDD2049 
Phosphatidylserine synthase 2 (PTDSS2) LDTP11284 36.76  LDD2049 
Phospholipase A2 group XV (PLA2G15) LDTP09088 48.84  LDD2049 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 25.11  LDD2049 
Plasma membrane calcium-transporting ATPase 1 (ATP2B1) LDTP03024 21.11  LDD2049 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 38.32  LDD2049 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 99.73  LDD2049 
Presenilin-associated rhomboid-like protein, mitochondrial (PARL) LDTP11852 27.10  LDD2049 
Presequence protease, mitochondrial (PITRM1) LDTP07003 28.44  LDD2049 
Probable glutathione peroxidase 8 (GPX8) LDTP09495 20.82  LDD2049 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 75.58  LDD2049 
Prolyl 3-hydroxylase 1 (P3H1) LDTP06750 29.86  LDD2049 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 27.47  LDD2049 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 46.21  LDD2049 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 46.21  LDD2049 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 26.72  LDD2049 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 30.70  LDD2049 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 53.08  LDD2049 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 31.56  LDD2049 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 81.57  LDD2049 
Rab-like protein 3 (RABL3) LDTP06986 23.59  LDD2049 
Ras-related protein Rab-11B (RAB11B) LDTP06501 99.73  LDD2049 
Ras-related protein Rab-1B (RAB1B) LDTP11733 23.75  LDD2049 
Ras-related protein Rab-24 (RAB24) LDTP10020 85.63  LDD2049 
Ras-related protein Rab-34 (RAB34) LDTP11535 21.11  LDD2049 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 62.68  LDD2049 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 93.70  LDD2049 
Retinol dehydrogenase 13 (RDH13) LDTP09061 38.05  LDD2049 
Ribonuclease T2 (RNASET2) LDTP00316 24.25  LDD2049 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 75.06  LDD2049 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 39.40  LDD2049 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 26.35  LDD2049 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 58.49  LDD2049 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 29.45  LDD2049 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 32.00  LDD2049 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 49.87  LDD2049 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 53.45  LDD2049 
Squalene monooxygenase (SQLE) LDTP06142 38.05  LDD2049 
Squalene synthase (FDFT1) LDTP03842 30.70  LDD2049 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 35.51  LDD2049 
Tissue alpha-L-fucosidase (FUCA1) LDTP02006 29.45  LDD2049 
Torsin-1B (TOR1B) LDTP00400 23.10  LDD2049 
Trimethyllysine dioxygenase, mitochondrial (TMLHE) LDTP12679 21.71  LDD2049 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 99.73  LDD2049 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 45.89  LDD2049 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 23.59  LDD2049 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 28.25  LDD2049 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 99.73  LDD2049 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 28.64  LDD2049 
------------------------------------------------------------------------------------
⏷ Show the Full List of 170 Enzyme
109 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 35.02  LDD2049 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 32.45  LDD2049 
Anoctamin-10 (ANO10) LDTP12704 28.05  LDD2049 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 99.73  LDD2049 
ATP synthase subunit a (MT-ATP6) LDTP01804 82.14  LDD2049 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 22.63  LDD2049 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 99.73  LDD2049 
B-cell receptor-associated protein 31 (BCAP31) LDTP04426 23.10  LDD2049 
BOS complex subunit NCLN (NCLN) LDTP10036 23.26  LDD2049 
Calcium load-activated calcium channel (TMCO1) LDTP13599 20.82  LDD2049 
Calcium uptake protein 1, mitochondrial (MICU1) LDTP11041 22.63  LDD2049 
Calnexin (CANX) LDTP03405 23.59  LDD2049 
Cation-dependent mannose-6-phosphate receptor (M6PR) LDTP03061 22.78  LDD2049 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 30.27  LDD2049 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 99.73  LDD2049 
Cytochrome c oxidase subunit 5A, mitochondrial (COX5A) LDTP03064 76.11  LDD2049 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 99.73  LDD2049 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 99.73  LDD2049 
Derlin-1 (DERL1) LDTP11245 21.71  LDD2049 
Dystroglycan 1 (DAG1) LDTP06039 21.71  LDD2049 
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) LDTP13393 24.42  LDD2049 
Endophilin-B1 (SH3GLB1) LDTP13953 22.01  LDD2049 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 26.72  LDD2049 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 82.14  LDD2049 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 99.73  LDD2049 
Erlin-2 (ERLIN2) LDTP01455 23.26  LDD2049 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 64.45  LDD2049 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 26.91  LDD2049 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 21.86  LDD2049 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 21.71  LDD2049 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 71.01  LDD2049 
Importin subunit alpha-1 (KPNA2) LDTP04501 21.41  LDD2049 
Iron-sulfur clusters transporter ABCB7, mitochondrial (ABCB7) LDTP01100 45.57  LDD2049 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 26.35  LDD2049 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 99.73  LDD2049 
Lysosome membrane protein 2 (SCARB2) LDTP06034 99.73  LDD2049 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 26.54  LDD2049 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 30.06  LDD2049 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 44.63  LDD2049 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 47.84  LDD2049 
Metal cation symporter ZIP14 (SLC39A14) LDTP06293 23.26  LDD2049 
Metaxin-1 (MTX1) LDTP05900 93.05  LDD2049 
Metaxin-2 (MTX2) LDTP01217 22.16  LDD2049 
MICOS complex subunit MIC26 (APOO) LDTP11250 38.32  LDD2049 
MICOS complex subunit MIC60 (IMMT) LDTP06660 31.56  LDD2049 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 25.28  LDD2049 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 21.11  LDD2049 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 25.46  LDD2049 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 30.91  LDD2049 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 30.27  LDD2049 
Mitochondrial chaperone BCS1 (BCS1L) LDTP13823 29.45  LDD2049 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 63.12  LDD2049 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 99.73  LDD2049 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 84.45  LDD2049 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 70.52  LDD2049 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 26.17  LDD2049 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 38.05  LDD2049 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 21.71  LDD2049 
Mpv17-like protein 2 (MPV17L2) LDTP14952 99.73  LDD2049 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 43.11  LDD2049 
Nucleoporin NDC1 (NDC1) LDTP11213 22.94  LDD2049 
Occludin (OCLN) LDTP06581 27.10  LDD2049 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 47.18  LDD2049 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 23.75  LDD2049 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 21.11  LDD2049 
Prenylated Rab acceptor protein 1 (RABAC1) LDTP13320 41.07  LDD2049 
Protein GPR107 (GPR107) LDTP07236 50.91  LDD2049 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 99.73  LDD2049 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 35.51  LDD2049 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 54.57  LDD2049 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 54.57  LDD2049 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 95.01  LDD2049 
Sideroflexin-4 (SFXN4) LDTP07531 22.32  LDD2049 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 27.47  LDD2049 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 99.73  LDD2049 
Solute carrier family 2, facilitated glucose transporter member 8 (SLC2A8) LDTP12809 34.30  LDD2049 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 99.73  LDD2049 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 24.76  LDD2049 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 23.75  LDD2049 
Sorting nexin-2 (SNX2) LDTP01043 33.36  LDD2049 
Sorting nexin-5 (SNX5) LDTP14174 29.86  LDD2049 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 29.86  LDD2049 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 99.73  LDD2049 
Surfeit locus protein 4 (SURF4) LDTP00592 25.99  LDD2049 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 49.18  LDD2049 
Tetraspanin-3 (TSPAN3) LDTP16813 99.73  LDD2049 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 24.25  LDD2049 
Translocator protein (TSPO) LDTP03546 23.10  LDD2049 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 99.73  LDD2049 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 32.67  LDD2049 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 37.27  LDD2049 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 31.34  LDD2049 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 44.94  LDD2049 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 21.56  LDD2049 
Transmembrane protein 126A (TMEM126A) LDTP15948 77.71  LDD2049 
Transmembrane protein 192 (TMEM192) LDTP08633 21.11  LDD2049 
Transmembrane protein 201 (TMEM201) LDTP07058 24.59  LDD2049 
Transmembrane protein 205 (TMEM205) LDTP07667 22.63  LDD2049 
Transmembrane protein 230 (TMEM230) LDTP10065 54.19  LDD2049 
Transmembrane protein 65 (TMEM65) LDTP07583 48.17  LDD2049 
Transmembrane protein 87A (TMEM87A) LDTP15481 99.73  LDD2049 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 61.39  LDD2049 
V-type proton ATPase subunit S1 (ATP6AP1) LDTP06499 34.06  LDD2049 
Vacuole membrane protein 1 (VMP1) LDTP10343 27.28  LDD2049 
Vang-like protein 1 (VANGL1) LDTP09288 61.82  LDD2049 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 99.73  LDD2049 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 99.73  LDD2049 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 99.73  LDD2049 
Wolframin (WFS1) LDTP01380 29.04  LDD2049 
------------------------------------------------------------------------------------
⏷ Show the Full List of 109 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 47.18  LDD2049 
NF-X1-type zinc finger protein NFXL1 (NFXL1) LDTP15183 27.47  LDD2049 
------------------------------------------------------------------------------------
4 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 41.93  LDD2049 
Coxsackievirus and adenovirus receptor (CXADR) LDTP05085 24.25  LDD2049 
HLA class I histocompatibility antigen, C alpha chain (HLA-C) LDTP02491 23.75  LDD2049 
Leukocyte surface antigen CD47 (CD47) LDTP05572 31.78  LDD2049 
------------------------------------------------------------------------------------
125 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) LDTP06291 26.54  LDD2049 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 27.28  LDD2049 
Ankyrin repeat domain-containing protein 13A (ANKRD13A) LDTP08682 36.25  LDD2049 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 29.65  LDD2049 
BolA-like protein 2 (BOLA2; BOLA2B) LDTP11870 23.92  LDD2049 
C-type mannose receptor 2 (MRC2) LDTP13114 31.78  LDD2049 
Calumenin (CALU) LDTP00887 22.94  LDD2049 
Centrin-2 (CETN2) LDTP03926 24.59  LDD2049 
Centrosomal protein 43 (CEP43) LDTP01652 27.67  LDD2049 
Clustered mitochondria protein homolog (CLUH) LDTP14486 28.64  LDD2049 
Coiled-coil domain-containing protein 127 (CCDC127) LDTP20361 21.86  LDD2049 
Coiled-coil domain-containing protein 6 (CCDC6) LDTP06515 21.56  LDD2049 
Cold-inducible RNA-binding protein (CIRBP) LDTP06022 24.59  LDD2049 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 29.04  LDD2049 
Conserved oligomeric Golgi complex subunit 3 (COG3) LDTP10452 34.30  LDD2049 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 99.73  LDD2049 
Cytochrome c oxidase assembly protein COX11, mitochondrial (COX11) LDTP14277 20.53  LDD2049 
Desmin (DES) LDTP02913 28.44  LDD2049 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 32.67  LDD2049 
DNA replication complex GINS protein PSF2 (GINS2) LDTP13802 44.32  LDD2049 
Dymeclin (DYM) LDTP08000 32.67  LDD2049 
Dynactin subunit 2 (DCTN2) LDTP05922 21.26  LDD2049 
Dynactin subunit 3 (DCTN3) LDTP01359 31.34  LDD2049 
Emerin (EMD) LDTP04356 40.79  LDD2049 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 63.12  LDD2049 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 99.73  LDD2049 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 27.28  LDD2049 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 38.32  LDD2049 
Galectin-3-binding protein (LGALS3BP) LDTP05558 51.27  LDD2049 
Ganglioside GM2 activator (GM2A) LDTP02927 75.58  LDD2049 
General transcription factor IIE subunit 1 (GTF2E1) LDTP03465 21.41  LDD2049 
Glycolipid transfer protein (GLTP) LDTP12891 34.54  LDD2049 
Golgi apparatus protein 1 (GLG1) LDTP09920 21.26  LDD2049 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 31.12  LDD2049 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 26.72  LDD2049 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 43.11  LDD2049 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 24.59  LDD2049 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 22.01  LDD2049 
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) LDTP05530 30.70  LDD2049 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 51.98  LDD2049 
Inner nuclear membrane protein Man1 (LEMD3) LDTP13913 24.59  LDD2049 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 40.22  LDD2049 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 99.73  LDD2049 
Kinetochore protein Spc24 (SPC24) LDTP09069 41.07  LDD2049 
Kinetochore protein Spc25 (SPC25) LDTP12192 30.27  LDD2049 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 41.36  LDD2049 
Large ribosomal subunit protein mL64 (GADD45GIP1) LDTP09297 25.28  LDD2049 
Large ribosomal subunit protein uL10m (MRPL10) LDTP08154 73.52  LDD2049 
LYR motif-containing protein 2 (LYRM2) LDTP18467 23.92  LDD2049 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 93.70  LDD2049 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 48.50  LDD2049 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 45.57  LDD2049 
MICOS complex subunit MIC27 (APOOL) LDTP07718 32.90  LDD2049 
Mitochondrial fission factor (MFF) LDTP11670 23.26  LDD2049 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 55.72  LDD2049 
Mitochondrial import receptor subunit TOM20 homolog (TOMM20) LDTP06373 22.47  LDD2049 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD2049 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 99.73  LDD2049 
Mitochondrial import receptor subunit TOM6 homolog (TOMM6) LDTP10113 91.14  LDD2049 
Negative elongation factor C/D (NELFCD) LDTP08594 40.79  LDD2049 
Neudesin (NENF) LDTP13630 76.11  LDD2049 
Neurofilament light polypeptide (NEFL) LDTP02180 34.30  LDD2049 
Nicastrin (NCSTN) LDTP09787 37.01  LDD2049 
Nucleobindin-1 (NUCB1) LDTP05375 99.73  LDD2049 
Nucleobindin-2 (NUCB2) LDTP05160 99.73  LDD2049 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 37.01  LDD2049 
Nurim (NRM) LDTP08606 30.27  LDD2049 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 41.07  LDD2049 
Optic atrophy 3 protein (OPA3) LDTP16006 88.03  LDD2049 
PIH1 domain-containing protein 1 (PIH1D1) LDTP12726 23.92  LDD2049 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 29.45  LDD2049 
Prohibitin-2 (PHB2) LDTP10924 41.93  LDD2049 
Protein bicaudal D homolog 2 (BICD2) LDTP09410 21.71  LDD2049 
Protein CEBPZOS (CEBPZOS) LDTP18883 99.73  LDD2049 
Protein CUSTOS (CUSTOS) LDTP18134 22.78  LDD2049 
Protein FAM114A2 (FAM114A2) LDTP16080 49.87  LDD2049 
Protein FAM162A (FAM162A) LDTP10056 99.73  LDD2049 
Protein FAM177A1 (FAM177A1) LDTP15398 44.02  LDD2049 
Protein FAM210A (FAM210A) LDTP15793 38.32  LDD2049 
Protein FAM3C (FAM3C) LDTP09773 51.27  LDD2049 
Protein jagunal homolog 1 (JAGN1) LDTP08904 34.30  LDD2049 
Protein LYRIC (MTDH) LDTP08224 32.45  LDD2049 
Protein SET (SET) LDTP05277 25.81  LDD2049 
Protein unc-119 homolog B (UNC119B) LDTP00105 28.64  LDD2049 
Protein YIF1A (YIF1A) LDTP01494 30.91  LDD2049 
Protein YIF1B (YIF1B) LDTP06948 34.54  LDD2049 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 24.42  LDD2049 
Regulator of microtubule dynamics protein 3 (RMDN3) LDTP10849 23.10  LDD2049 
Reticulocalbin-2 (RCN2) LDTP06097 61.39  LDD2049 
Reticulon-2 (RTN2) LDTP01167 99.73  LDD2049 
Reticulon-3 (RTN3) LDTP01522 82.14  LDD2049 
Reticulon-4 (RTN4) LDTP12412 75.06  LDD2049 
RNA-binding motif protein, X chromosome (RBMX) LDTP03850 21.11  LDD2049 
RNA-binding protein 3 (RBM3) LDTP05226 40.22  LDD2049 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 67.65  LDD2049 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 23.26  LDD2049 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 22.63  LDD2049 
Sterol regulatory element-binding protein cleavage-activating protein (SCAP) LDTP05643 25.99  LDD2049 
Synaptogyrin-2 (SYNGR2) LDTP00859 31.34  LDD2049 
Synaptosomal-associated protein 29 (SNAP29) LDTP01661 31.78  LDD2049 
Syntaxin-10 (STX10) LDTP00986 65.34  LDD2049 
Syntaxin-18 (STX18) LDTP13086 99.73  LDD2049 
Syntaxin-7 (STX7) LDTP00632 45.25  LDD2049 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 23.43  LDD2049 
TBC1 domain family member 10A (TBC1D10A) LDTP11379 20.82  LDD2049 
Testis-expressed protein 264 (TEX264) LDTP14259 48.50  LDD2049 
Tetraspanin-6 (TSPAN6) LDTP14458 97.01  LDD2049 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 21.41  LDD2049 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 41.64  LDD2049 
TraB domain-containing protein (TRABD) LDTP19963 51.63  LDD2049 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 29.24  LDD2049 
Translocon-associated protein subunit delta (SSR4) LDTP04425 26.91  LDD2049 
Trophoblast glycoprotein (TPBG) LDTP05960 30.27  LDD2049 
Tubulin beta chain (TUBB) LDTP02205 32.00  LDD2049 
Tubulin beta-2A chain (TUBB2A) LDTP05998 22.32  LDD2049 
Tubulin beta-2B chain (TUBB2B) LDTP11277 22.16  LDD2049 
Tubulin beta-4B chain (TUBB4B) LDTP05076 28.44  LDD2049 
Tubulin beta-6 chain (TUBB6) LDTP11233 21.56  LDD2049 
Tumor protein D52 (TPD52) LDTP04703 22.01  LDD2049 
Ubiquilin-2 (UBQLN2) LDTP13273 25.46  LDD2049 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 99.73  LDD2049 
Vacuolar protein sorting-associated protein 18 homolog (VPS18) LDTP13019 21.71  LDD2049 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 30.48  LDD2049 
Vimentin (VIM) LDTP02297 28.64  LDD2049 
Zinc finger CCHC domain-containing protein 3 (ZCCHC3) LDTP12623 35.02  LDD2049 
------------------------------------------------------------------------------------
⏷ Show the Full List of 125 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD2049 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587