Details of the Target

General Information of Target

Target ID LDTP10113
Target Name Mitochondrial import receptor subunit TOM6 homolog (TOMM6)
Gene Name TOMM6
Gene ID 100188893
Synonyms
OBTP; TOM6; Mitochondrial import receptor subunit TOM6 homolog; Overexpressed breast tumor protein; Translocase of outer membrane 6 kDa subunit homolog
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPSAFSVSSFPVSIPAVLTQTDWTEPWLMGLATFHALCVLLTCLSSRSYRLQIGHFLCLV
ILVYCAEYINEAAAMNWRLFSKYQYFDSRGMFISIVFSAPLLVNAMIIVVMWVWKTLNVM
TDLKNAQERRKEKKRRRKED
Target Bioclass
Other
Family
Tom6 family
Subcellular location
Mitochondrion outer membrane
Uniprot ID
Q96B49
Ensemble ID
ENST00000398881.4
HGNC ID
HGNC:34528

Probe(s) Labeling This Target

PAL-AfBPP Probe
Click To Hide/Show 12 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C053
 Probe Info  		9.85  LDD1751  [1]
C106
 Probe Info  		28.44  LDD1793  [1]
C107
 Probe Info  		6.45  LDD1794  [1]
C112
 Probe Info  		99.73  LDD1799  [1]
C231
 Probe Info  		12.47  LDD1904  [1]
C232
 Probe Info  		36.76  LDD1905  [1]
C235
 Probe Info  		18.13  LDD1908  [1]
C293
 Probe Info  		60.13  LDD1963  [1]
C296
 Probe Info  		23.26  LDD1966  [1]
C390
 Probe Info  		91.14  LDD2049  [1]
C429
 Probe Info  		35.75  LDD2084  [1]
C431
 Probe Info  		60.13  LDD2086  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Ceramide synthase 4 (CERS4) . Q9HA82
Transporter and channel
Click To Hide/Show 4 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Hepatic sodium/bile acid cotransporter (SLC10A1) Bile acid:sodium symporter (BASS) family Q14973
Synaptic vesicular amine transporter (SLC18A2) Vesicular transporter family Q05940
Aquaporin-6 (AQP6) MIP/aquaporin (TC 1.A.8) family Q13520
Transmembrane protein 14B (TMEM14B) TMEM14 family Q9NUH8
GPCR
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Free fatty acid receptor 3 (FFAR3) G-protein coupled receptor 1 family O14843
Other
Click To Hide/Show 3 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) ERGIC family Q9Y282
Macrosialin (CD68) LAMP family P34810
Outer dense fiber protein 4 (ODF4) . Q2M2E3

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587