Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C293  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 158 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00697  Cytochrome b5 type B (CYB5B) 99.7
 LDTP15328  Dolichyldiphosphatase 1 (DOLPP1) 99.7
 LDTP02359  Heme oxygenase 1 (HMOX1) 90.5
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 79.9
 LDTP12873  CDGSH iron-sulfur domain-containing protein 1 (CISD1) 78.8
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 71.5
 LDTP13189  Cytochrome b-c1 complex subunit 9 (UQCR10) 70.0
 LDTP04247  Protein farnesyltransferase subunit beta (FNTB) 66.3
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 64.0
 LDTP13352  GTP:AMP phosphotransferase AK3, mitochondrial (AK3) 63.1
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 60.5
 LDTP03540  Heme oxygenase 2 (HMOX2) 55.7
 LDTP00486  Cytochrome b-c1 complex subunit 8 (UQCRQ) 54.9
 LDTP11127  ADP-dependent glucokinase (ADPGK) 52.7
 LDTP11225  Deoxyhypusine hydroxylase (DOHH) 48.2
 LDTP14218  Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) 46.9
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 43.4
 LDTP05905  Acid ceramidase (ASAH1) 42.8
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 42.8
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 42.2
 LDTP09799  DCN1-like protein 4 (DCUN1D4) 42.2
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 41.9
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 38.6
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 38.1
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 37.3
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 37.0
 LDTP02505  Lysosomal protective protein (CTSA) 36.8
 LDTP03145  Catechol O-methyltransferase (COMT) 36.5
 LDTP12868  Endoplasmic reticulum aminopeptidase 1 (ERAP1) 36.3
 LDTP14030  V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) 35.8
 LDTP13620  Lysosomal thioesterase PPT2 (PPT2) 35.5
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 35.0
 LDTP13154  E3 ubiquitin-protein ligase RNF14 (RNF14) 34.1
 LDTP10188  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) 34.1
 LDTP09155  Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3) 33.4
 LDTP05128  Glutathione S-transferase omega-1 (GSTO1) 33.1
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 32.7
 LDTP12318  Calcium-independent phospholipase A2-gamma (PNPLA8) 32.0
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 31.3
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 31.1
 LDTP09396  Minor histocompatibility antigen H13 (HM13) 30.1
 LDTP08728  Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) 30.1
 LDTP06977  GPI ethanolamine phosphate transferase 2 (PIGG) 28.6
 LDTP06501  Ras-related protein Rab-11B (RAB11B) 28.6
 LDTP10329  Ceramide synthase 2 (CERS2) 28.1
 LDTP12013  dCTP pyrophosphatase 1 (DCTPP1) 27.9
 LDTP08177  Dehydrodolichyl diphosphate synthase complex subunit DHDDS (DHDDS) 27.9
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 27.9
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 27.5
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 27.5
 LDTP13408  Cell division cycle protein 23 homolog (CDC23) 27.3
 LDTP13220  Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) 27.3
 LDTP11259  Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) 26.7
 LDTP05758  S-methyl-5'-thioadenosine phosphorylase (MTAP) 26.7
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 26.5
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 26.5
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 26.4
 LDTP12633  Probable ATP-dependent RNA helicase DDX28 (DDX28) 26.2
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 26.0
 LDTP05029  Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) 26.0
 LDTP00032  2-hydroxyacyl-CoA lyase 2 (ILVBL) 25.6
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 25.1
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 24.6
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 24.4
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1) 24.3
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 24.3
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 23.8
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) 23.4
 LDTP02799  N-acetylglucosamine-6-sulfatase (GNS) 23.4
 LDTP00907  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) 23.3
 LDTP06142  Squalene monooxygenase (SQLE) 23.3
 LDTP01982  NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) 23.1
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 22.5
 LDTP02385  Leukotriene A-4 hydrolase (LTA4H) 22.5
 LDTP03417  Proteasome subunit beta type-4 (PSMB4) 22.5
 LDTP04911  Ras-related protein Rap-2b (RAP2B) 22.5
 LDTP12639  1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (AGPAT5) 22.3
 LDTP04008  Endothelin-converting enzyme 1 (ECE1) 22.2
 LDTP01770  NADH-cytochrome b5 reductase 3 (CYB5R3) 22.2
 LDTP10471  Protein disulfide-isomerase TMX3 (TMX3) 22.0
 LDTP01769  Dihydrofolate reductase (DHFR) 21.9
 LDTP10930  Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) 21.9
 LDTP00844  Maleylacetoacetate isomerase (GSTZ1) 21.7
 LDTP07003  Presequence protease, mitochondrial (PITRM1) 21.7
 LDTP09395  Signal peptide peptidase-like 2A (SPPL2A) 21.7
 LDTP12954  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) 21.6
 LDTP04471  Ribosomal protein S6 kinase alpha-3 (RPS6KA3) 21.4
 LDTP03854  Vitamin K-dependent gamma-carboxylase (GGCX) 21.4
 LDTP11321  Acetyl-CoA acetyltransferase, cytosolic (ACAT2) 21.3
 LDTP10020  Ras-related protein Rab-24 (RAB24) 21.3
 LDTP09251  Atlastin-2 (ATL2) 21.1
 LDTP09095  Diacylglycerol lipase-beta (DAGLB) 21.1
 LDTP01430  E3 ubiquitin-protein ligase listerin (LTN1) 21.1
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 21.0
 LDTP09256  Putative phospholipase B-like 2 (PLBD2) 21.0
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 20.8
 LDTP05461  Protein kinase C delta type (PRKCD) 20.8
 LDTP02169  Beta-hexosaminidase subunit alpha (HEXA) 20.7
 LDTP13367  Glutathione hydrolase 7 (GGT7) 20.5
 LDTP06645  Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) 20.5
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 20.5
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 20.4
 LDTP10182  TLC domain-containing protein 1 (TLCD1) 20.4
 LDTP13140  tRNA (guanine-N(7)-)-methyltransferase (METTL1) 20.3
 LDTP01743  NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) 20.1
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 20.0
 LDTP13358  Leucyl-cystinyl aminopeptidase (LNPEP) 19.7
 LDTP10249  Metalloendopeptidase OMA1, mitochondrial (OMA1) 19.7
 LDTP05476  3-ketodihydrosphingosine reductase (KDSR) 19.6
 LDTP07931  Heme A synthase COX15 (COX15) 19.6
 LDTP05632  Mitochondrial-processing peptidase subunit alpha (PMPCA) 19.6
 LDTP01562  Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) 19.6
 LDTP12470  GTP-binding protein SAR1a (SAR1A) 19.3
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1) 19.3
 LDTP02260  Beta-glucuronidase (GUSB) 19.2
 LDTP02539  Lysosomal acid phosphatase (ACP2) 19.0
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 19.0
 LDTP02141  Alpha-galactosidase A (GLA) 18.9
 LDTP11081  NAD-capped RNA hydrolase NUDT12 (NUDT12) 18.9
 LDTP00589  Peroxisomal acyl-coenzyme A oxidase 3 (ACOX3) 18.9
 LDTP02837  Beta-galactosidase (GLB1) 18.8
 LDTP04531  Hexokinase-2 (HK2) 18.8
 LDTP12610  Obg-like ATPase 1 (OLA1) 18.8
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 18.8
 LDTP01219  NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) 18.6
 LDTP11273  N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) 18.5
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 18.5
 LDTP06371  GTP-binding protein Rheb (RHEB) 18.3
 LDTP02188  Protein disulfide-isomerase (P4HB) 18.3
 LDTP04895  Ras-related protein Rab-10 (RAB10) 18.3
 LDTP05408  Antigen peptide transporter 1 (TAP1) 18.1
 LDTP09874  Endoplasmic reticulum protein SC65 (P3H4) 18.1
 LDTP11319  Threonine--tRNA ligase, mitochondrial (TARS2) 18.1
 LDTP12720  Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) 18.0
 LDTP07868  Protein O-mannosyl-transferase TMTC3 (TMTC3) 17.9
 LDTP12415  Adenosine 5'-monophosphoramidase HINT3 (HINT3) 17.8
 LDTP07104  All trans-polyprenyl-diphosphate synthase PDSS1 (PDSS1) 17.8
 LDTP00400  Torsin-1B (TOR1B) 17.8
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 17.8
 LDTP13486  Long-chain-fatty-acid--CoA ligase 6 (ACSL6) 17.6
 LDTP15370  Pseudouridylate synthase RPUSD2 (RPUSD2) 17.6
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 17.5
 LDTP12679  Trimethyllysine dioxygenase, mitochondrial (TMLHE) 17.5
 LDTP00536  Mitochondrial ribonuclease P catalytic subunit (PRORP) 17.3
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 17.3
 LDTP12163  Calcyclin-binding protein (CACYBP) 17.1
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 17.1
 LDTP16025  Ketosamine-3-kinase (FN3KRP) 16.7
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 16.7
 LDTP05850  Probable methyltransferase TARBP1 (TARBP1) 16.4
 LDTP04712  Puromycin-sensitive aminopeptidase (NPEPPS) 16.3
 LDTP12180  Retinol dehydrogenase 14 (RDH14) 16.3
 LDTP08512  Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCAT) 16.1
 LDTP04634  Alpha-N-acetylglucosaminidase (NAGLU) 16.0
 LDTP00783  Beta-1,4-glucuronyltransferase 1 (B4GAT1) 16.0
 LDTP10530  Beta-1,3-galactosyltransferase 6 (B3GALT6) 15.9
 LDTP10137  Cytochrome c oxidase assembly factor 7 (COA7) 15.9
 LDTP13959  Dehydrogenase/reductase SDR family member 7 (DHRS7) 15.9
Transporter and channel
Click to Show/Hide to Show 117 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 99.7
 LDTP11927  Essential MCU regulator, mitochondrial (SMDT1) 94.4
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 91.8
 LDTP20002  Transmembrane protein 160 (TMEM160) 83.9
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 81.0
 LDTP15648  BRI3-binding protein (BRI3BP) 73.5
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 70.0
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 69.6
 LDTP01804  ATP synthase subunit a (MT-ATP6) 66.7
 LDTP04789  Synaptojanin-2-binding protein (SYNJ2BP) 66.3
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 56.1
 LDTP06221  StAR-related lipid transfer protein 3 (STARD3) 56.1
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 54.9
 LDTP11615  Protein tweety homolog 3 (TTYH3) 52.7
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 52.0
 LDTP04956  Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) 52.0
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 49.2
 LDTP11250  MICOS complex subunit MIC26 (APOO) 46.9
 LDTP00262  Acetyl-coenzyme A transporter 1 (SLC33A1) 45.9
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 42.5
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 41.6
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 41.6
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 41.6
 LDTP15948  Transmembrane protein 126A (TMEM126A) 41.1
 LDTP07304  Autophagy-related protein 16-1 (ATG16L1) 40.8
 LDTP07156  Protein wntless homolog (WLS) 40.8
 LDTP14099  Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) 39.9
 LDTP15481  Transmembrane protein 87A (TMEM87A) 39.7
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 39.1
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 37.5
 LDTP00547  Secretory carrier-associated membrane protein 2 (SCAMP2) 37.5
 LDTP10343  Vacuole membrane protein 1 (VMP1) 37.5
 LDTP14200  Mitochondrial ornithine transporter 1 (SLC25A15) 37.3
 LDTP08327  Osteopetrosis-associated transmembrane protein 1 (OSTM1) 37.0
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 36.5
 LDTP13262  Signal recognition particle subunit SRP68 (SRP68) 36.0
 LDTP05900  Metaxin-1 (MTX1) 34.8
 LDTP12207  Putative divalent cation/proton antiporter TMEM165 (TMEM165) 34.5
 LDTP10669  Melanoma inhibitory activity protein 2 (MIA2) 34.3
 LDTP07236  Protein GPR107 (GPR107) 34.1
 LDTP00857  Syntaxin-6 (STX6) 32.7
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 32.0
 LDTP18459  StAR-related lipid transfer protein 7, mitochondrial (STARD7) 31.8
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 31.3
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 30.7
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 30.5
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 29.7
 LDTP02071  Amyloid-beta precursor protein (APP) 29.2
 LDTP11245  Derlin-1 (DERL1) 29.0
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 27.9
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 27.9
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 27.3
 LDTP08981  Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) 26.7
 LDTP10065  Transmembrane protein 230 (TMEM230) 26.5
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 26.2
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 25.6
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 25.6
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 25.1
 LDTP02608  ADP/ATP translocase 1 (SLC25A4) 24.8
 LDTP15979  Transmembrane protein 245 (TMEM245) 24.8
 LDTP18153  Major facilitator superfamily domain-containing protein 3 (MFSD3) 24.4
 LDTP03380  Stomatin (STOM) 24.3
 LDTP01060  PRA1 family protein 2 (PRAF2) 24.1
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 23.9
 LDTP00310  Syntenin-1 (SDCBP) 23.9
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 23.8
 LDTP01671  STARD3 N-terminal-like protein (STARD3NL) 23.3
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 22.9
 LDTP16190  Protein FAM8A1 (FAM8A1) 22.2
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 22.2
 LDTP08881  Transmembrane protein 199 (TMEM199) 22.0
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 21.7
 LDTP09144  Metal transporter CNNM3 (CNNM3) 21.6
 LDTP02058  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (RPN2) 21.3
 LDTP03905  Peroxisomal biogenesis factor 19 (PEX19) 21.3
 LDTP12191  Vezatin (VEZT) 21.3
 LDTP11213  Nucleoporin NDC1 (NDC1) 21.0
 LDTP06633  Reticulon-1 (RTN1) 21.0
 LDTP01574  Importin-7 (IPO7) 20.8
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 20.7
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 20.5
 LDTP06198  Major facilitator superfamily domain-containing protein 10 (MFSD10) 20.4
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 20.4
 LDTP00541  NPC intracellular cholesterol transporter 1 (NPC1) 20.4
 LDTP02562  Lysosome-associated membrane glycoprotein 1 (LAMP1) 20.3
 LDTP02215  Prosaposin (PSAP) 20.1
 LDTP01051  Target of Myb1 membrane trafficking protein (TOM1) 20.0
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 19.8
 LDTP11607  Exportin-4 (XPO4) 19.7
 LDTP10036  BOS complex subunit NCLN (NCLN) 19.3
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 18.6
 LDTP04787  Transmembrane protein 33 (TMEM33) 18.6
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 18.4
 LDTP10985  Equilibrative nucleoside transporter 1 (SLC29A1) 18.0
 LDTP01200  Peroxisomal membrane protein PEX14 (PEX14) 17.9
 LDTP08016  Proton-coupled amino acid transporter 1 (SLC36A1) 17.9
 LDTP05780  Syntaxin-5 (STX5) 17.9
 LDTP01380  Wolframin (WFS1) 17.8
 LDTP09203  Nucleoporin Nup37 (NUP37) 17.6
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) 17.5
 LDTP01160  Peroxisomal membrane protein 11A (PEX11A) 17.5
 LDTP07477  Transmembrane protein 214 (TMEM214) 17.4
 LDTP14717  ATP synthase subunit e, mitochondrial (ATP5ME) 17.3
 LDTP01542  Golgi SNAP receptor complex member 1 (GOSR1) 17.3
 LDTP08673  Calcium uptake protein 2, mitochondrial (MICU2) 17.0
 LDTP10533  Sorting nexin-27 (SNX27) 17.0
 LDTP06660  MICOS complex subunit MIC60 (IMMT) 16.9
 LDTP11406  Transmembrane protein 59 (TMEM59) 16.9
 LDTP09333  Golgin subfamily A member 5 (GOLGA5) 16.8
 LDTP05811  Syntaxin-3 (STX3) 16.6
 LDTP02010  Annexin A1 (ANXA1) 16.3
 LDTP07667  Transmembrane protein 205 (TMEM205) 16.3
 LDTP09459  Volume-regulated anion channel subunit LRRC8C (LRRC8C) 16.2
 LDTP15898  HIG1 domain family member 2A, mitochondrial (HIGD2A) 16.1
 LDTP15967  Tetraspanin-10 (TSPAN10) 16.1
 LDTP00590  Protein RER1 (RER1) 16.0
 LDTP02087  ADP/ATP translocase 2 (SLC25A5) 15.9
Transcription factor
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04683  Peregrin (BRPF1) 18.6
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 16.9
Immunoglobulin
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05572  Leukocyte surface antigen CD47 (CD47) 24.4
Other
Click to Show/Hide to Show 119 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 99.7
 LDTP14458  Tetraspanin-6 (TSPAN6) 99.7
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 97.7
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 94.4
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 88.0
 LDTP11076  Apolipoprotein L2 (APOL2) 85.0
 LDTP14259  Testis-expressed protein 264 (TEX264) 79.3
 LDTP10113  Mitochondrial import receptor subunit TOM6 homolog (TOMM6) 60.1
 LDTP18883  Protein CEBPZOS (CEBPZOS) 60.1
 LDTP01522  Reticulon-3 (RTN3) 58.5
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 58.1
 LDTP03926  Centrin-2 (CETN2) 57.7
 LDTP06892  Protein Hikeshi (HIKESHI) 56.1
 LDTP05160  Nucleobindin-2 (NUCB2) 55.3
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 53.8
 LDTP07839  Capping protein-inhibiting regulator of actin dynamics (CRACD) 49.9
 LDTP13086  Syntaxin-18 (STX18) 49.2
 LDTP01050  Small ribosomal subunit protein uS14m (MRPS14) 47.5
 LDTP19780  Keratinocyte-associated transmembrane protein 2 (KCT2) 45.6
 LDTP15002  Armadillo-like helical domain-containing protein 3 (ARMH3) 41.4
 LDTP00105  Protein unc-119 homolog B (UNC119B) 40.2
 LDTP12412  Reticulon-4 (RTN4) 39.9
 LDTP12287  Ran guanine nucleotide release factor (RANGRF) 39.7
 LDTP02443  Calmodulin-3 (CALM3) 38.6
 LDTP08154  Large ribosomal subunit protein uL10m (MRPL10) 38.1
 LDTP10056  Protein FAM162A (FAM162A) 37.5
 LDTP19963  TraB domain-containing protein (TRABD) 36.5
 LDTP00859  Synaptogyrin-2 (SYNGR2) 36.3
 LDTP15240  LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) 35.3
 LDTP16080  Protein FAM114A2 (FAM114A2) 35.3
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 34.3
 LDTP00871  Microtubule nucleation factor SSNA1 (SSNA1) 34.1
 LDTP19859  Small integral membrane protein 12 (SMIM12) 33.6
 LDTP15067  Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) 33.1
 LDTP04652  Eukaryotic translation initiation factor 5 (EIF5) 32.2
 LDTP01494  Protein YIF1A (YIF1A) 30.9
 LDTP12642  CYFIP-related Rac1 interactor B (CYRIB) 30.7
 LDTP11981  Receptor expression-enhancing protein 4 (REEP4) 30.7
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 30.1
 LDTP15887  Lipase maturation factor 2 (LMF2) 29.0
 LDTP15095  Receptor expression-enhancing protein 3 (REEP3) 28.6
 LDTP08689  Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) 28.2
 LDTP15398  Protein FAM177A1 (FAM177A1) 27.7
 LDTP08224  Protein LYRIC (MTDH) 27.5
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 26.7
 LDTP07891  Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) 26.7
 LDTP11044  Polyadenylate-binding protein-interacting protein 2 (PAIP2) 26.5
 LDTP04382  Kinetochore-associated protein 1 (KNTC1) 25.6
 LDTP05586  Protein VAC14 homolog (VAC14) 25.6
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 25.5
 LDTP01075  Protein CutA (CUTA) 25.5
 LDTP06097  Reticulocalbin-2 (RCN2) 25.5
 LDTP16006  Optic atrophy 3 protein (OPA3) 25.3
 LDTP02927  Ganglioside GM2 activator (GM2A) 25.1
 LDTP10656  Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP3) 24.9
 LDTP14263  TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) 24.8
 LDTP00417  Programmed cell death protein 5 (PDCD5) 24.4
 LDTP15741  Cytochrome c oxidase assembly protein COX14 (COX14) 24.3
 LDTP00376  Coatomer subunit epsilon (COPE) 23.8
 LDTP00850  ER lumen protein-retaining receptor 3 (KDELR3) 22.8
 LDTP09773  Protein FAM3C (FAM3C) 22.6
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 22.6
 LDTP12623  Zinc finger CCHC domain-containing protein 3 (ZCCHC3) 22.6
 LDTP16285  Transducin beta-like protein 2 (TBL2) 22.3
 LDTP05715  Vesicle transport protein SEC20 (BNIP1) 22.2
 LDTP11326  FUN14 domain-containing protein 2 (FUNDC2) 22.0
 LDTP08606  Nurim (NRM) 22.0
 LDTP13908  AP-3 complex subunit mu-1 (AP3M1) 21.7
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 21.4
 LDTP11978  HAUS augmin-like complex subunit 4 (HAUS4) 21.1
 LDTP16322  Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) 21.0
 LDTP10825  Oxysterol-binding protein-related protein 9 (OSBPL9) 20.8
 LDTP10184  HAUS augmin-like complex subunit 1 (HAUS1) 20.5
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 20.5
 LDTP13606  Mammalian ependymin-related protein 1 (EPDR1) 20.5
 LDTP07368  Tetratricopeptide repeat protein 19, mitochondrial (TTC19) 20.4
 LDTP10775  Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) 20.1
 LDTP00913  Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A) 20.1
 LDTP19005  SLC35A4 upstream open reading frame protein (SLC35A4) 20.1
 LDTP10990  T-complex protein 1 subunit eta (CCT7) 20.0
 LDTP04979  U6 snRNA-associated Sm-like protein LSm3 (LSM3) 19.8
 LDTP09813  CCR4-NOT transcription complex subunit 9 (CNOT9) 19.7
 LDTP05375  Nucleobindin-1 (NUCB1) 19.4
 LDTP03352  Splicing factor U2AF 65 kDa subunit (U2AF2) 19.4
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 19.0
 LDTP03775  RNA-binding protein FUS (FUS) 19.0
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 18.8
 LDTP06022  Cold-inducible RNA-binding protein (CIRBP) 18.5
 LDTP12468  Diablo IAP-binding mitochondrial protein (DIABLO) 18.3
 LDTP18272  Transmembrane protein 209 (TMEM209) 18.3
 LDTP14716  ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) 18.0
 LDTP19021  EF-hand calcium-binding domain-containing protein 14 (EFCAB14) 17.8
 LDTP14164  Immediate early response 3-interacting protein 1 (IER3IP1) 17.8
 LDTP10700  KH domain-containing RNA-binding protein QKI (QKI) 17.8
 LDTP05257  Receptor expression-enhancing protein 5 (REEP5) 17.6
 LDTP04425  Translocon-associated protein subunit delta (SSR4) 17.6
 LDTP00555  BET1 homolog (BET1) 17.5
 LDTP00500  Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) 17.4
 LDTP04514  Heterogeneous nuclear ribonucleoprotein F (HNRNPF) 17.4
 LDTP08364  Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) 17.3
 LDTP01246  KH domain-containing, RNA-binding, signal transduction-associated protein 3 (KHDRBS3) 17.1
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 17.1
 LDTP09787  Nicastrin (NCSTN) 17.1
 LDTP00887  Calumenin (CALU) 17.0
 LDTP10403  DDRGK domain-containing protein 1 (DDRGK1) 17.0
 LDTP01466  HAUS augmin-like complex subunit 5 (HAUS5) 17.0
 LDTP15269  Large ribosomal subunit protein mL55 (MRPL55) 17.0
 LDTP12476  Translation initiation factor eIF2B subunit gamma (EIF2B3) 17.0
 LDTP02297  Vimentin (VIM) 17.0
 LDTP04207  Heat shock 70 kDa protein 13 (HSPA13) 16.9
 LDTP13402  Dynactin subunit 4 (DCTN4) 16.6
 LDTP05277  Protein SET (SET) 16.6
 LDTP07934  Synaptic vesicle glycoprotein 2A (SV2A) 16.6
 LDTP14792  Small ribosomal subunit protein uS9m (MRPS9) 16.4
 LDTP19924  Protein PBDC1 (PBDC1) 16.3
 LDTP15253  HEAT repeat-containing protein 3 (HEATR3) 16.0
 LDTP14277  Cytochrome c oxidase assembly protein COX11, mitochondrial (COX11) 15.9
 LDTP05855  Cytoplasmic dynein 1 intermediate chain 2 (DYNC1I2) 15.9
 LDTP00991  Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) 15.9

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587