Target ID	LDTP13828
Target Name	Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3)
Gene Name	ERGIC3
Gene ID	51614
Synonyms	C20orf47; ERV46; SDBCAG84; Endoplasmic reticulum-Golgi intermediate compartment protein 3; Serologically defined breast cancer antigen NY-BR-84
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MASGVTVNDEVIKVFNDMKVRKSSTQEEIKKRKKAVLFCLSDDKRQIIVEEAKQILVGDI GDTVEDPYTSFVKLLPLNDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASS KDAIKKKFTGIKHEWQVNGLDDIKDRSTLGEKLGGNVVVSLEGKPL
Target Bioclass	Other
Family	ERGIC family
Subcellular location	Endoplasmic reticulum-Golgi intermediate compartment membrane
Function	Possible role in transport between endoplasmic reticulum and Golgi. Positively regulates trafficking of the secretory proteins SERPINA1/alpha1-antitrypsin and HP/haptoglobin.
Uniprot ID	Q9Y282
Ensemble ID	ENST00000348547.7
HGNC ID	HGNC:15927

Cell line	Mutation details			Probe for labeling this protein in this cell
NCIH82	SNV: p.E57Ter			.
OVCAR8	SNV: p.T52R			.
SNGM	SNV: p.G212R			.
SUPT1	SNV: p.G252R			.

Probe name		Structure	Binding Site(Ratio)	Interaction ID	Ref
CHEMBL5175495  Probe Info			7.94	LDD0196	[1]
TH211  Probe Info			Y13(10.37)	LDD0260	[2]
STPyne  Probe Info			K8(4.44)	LDD0277	[3]
Probe 1  Probe Info			Y13(45.67); Y287(6.02)	LDD3495	[4]
DBIA  Probe Info			C182(0.97)	LDD3312	[5]
JZ128-DTB  Probe Info			N.A.	LDD0462	[6]
5E-2FA  Probe Info			N.A.	LDD2235	[7]
4-Iodoacetamidophenylacetylene  Probe Info			C199(0.00); C182(0.00)	LDD0038	[8]
IA-alkyne  Probe Info			C199(0.00); C182(0.00)	LDD0036	[8]
Lodoacetamide azide  Probe Info			C81(0.00); C199(0.00); C182(0.00)	LDD0037	[8]
AOyne  Probe Info			14.40	LDD0443	[9]
NAIA_5  Probe Info			C182(0.00); C199(0.00)	LDD2223	[10]

Probe name		Structure	Binding Site(Ratio)	Interaction ID	Ref
C001  Probe Info			5.74	LDD1711	[11]
C004  Probe Info			8.82	LDD1714	[11]
C007  Probe Info			5.13	LDD1716	[11]
C010  Probe Info			5.50	LDD1719	[11]
C011  Probe Info			5.78	LDD1720	[11]
C017  Probe Info			6.32	LDD1725	[11]
C022  Probe Info			14.83	LDD1728	[11]
C026  Probe Info			6.68	LDD1732	[11]
C039  Probe Info			4.96	LDD1739	[11]
C040  Probe Info			18.51	LDD1740	[11]
C041  Probe Info			12.38	LDD1741	[11]
C044  Probe Info			5.54	LDD1743	[11]
C049  Probe Info			11.88	LDD1747	[11]
C053  Probe Info			7.11	LDD1751	[11]
C055  Probe Info			33.82	LDD1752	[11]
C056  Probe Info			42.52	LDD1753	[11]
C059  Probe Info			22.16	LDD1756	[11]
C060  Probe Info			14.52	LDD1757	[11]
C063  Probe Info			28.05	LDD1760	[11]
C064  Probe Info			7.46	LDD1761	[11]
C065  Probe Info			5.31	LDD1762	[11]
C067  Probe Info			11.79	LDD1763	[11]
C070  Probe Info			21.86	LDD1766	[11]
C071  Probe Info			11.88	LDD1767	[11]
C072  Probe Info			16.11	LDD1768	[11]
C082  Probe Info			10.63	LDD1774	[11]
C085  Probe Info			16.68	LDD1777	[11]
C091  Probe Info			23.59	LDD1782	[11]
C092  Probe Info			50.91	LDD1783	[11]
C094  Probe Info			59.30	LDD1785	[11]
C095  Probe Info			9.25	LDD1786	[11]
C100  Probe Info			10.06	LDD1789	[11]
C106  Probe Info			24.08	LDD1793	[11]
C107  Probe Info			12.47	LDD1794	[11]
C108  Probe Info			12.91	LDD1795	[11]
C112  Probe Info			51.27	LDD1799	[11]
C129  Probe Info			15.67	LDD1811	[11]
C130  Probe Info			12.47	LDD1812	[11]
C134  Probe Info			40.22	LDD1816	[11]
C135  Probe Info			12.55	LDD1817	[11]
C139  Probe Info			12.04	LDD1821	[11]
C140  Probe Info			15.67	LDD1822	[11]
C141  Probe Info			95.67	LDD1823	[11]
C143  Probe Info			37.27	LDD1825	[11]
C145  Probe Info			10.20	LDD1827	[11]
C147  Probe Info			9.85	LDD1829	[11]
C153  Probe Info			37.79	LDD1834	[11]
C156  Probe Info			9.71	LDD1836	[11]
C159  Probe Info			28.05	LDD1839	[11]
C160  Probe Info			31.34	LDD1840	[11]
C161  Probe Info			45.89	LDD1841	[11]
C163  Probe Info			33.36	LDD1843	[11]
C165  Probe Info			25.28	LDD1845	[11]
C166  Probe Info			10.06	LDD1846	[11]
C169  Probe Info			99.73	LDD1849	[11]
C170  Probe Info			8.28	LDD1850	[11]
C172  Probe Info			5.35	LDD1852	[11]
C173  Probe Info			8.82	LDD1853	[11]
C174  Probe Info			5.13	LDD1854	[11]
C177  Probe Info			10.27	LDD1856	[11]
C178  Probe Info			38.85	LDD1857	[11]
C183  Probe Info			12.21	LDD1861	[11]
C185  Probe Info			5.10	LDD1863	[11]
C186  Probe Info			13.45	LDD1864	[11]
C187  Probe Info			38.32	LDD1865	[11]
C191  Probe Info			18.25	LDD1868	[11]
C193  Probe Info			13.36	LDD1869	[11]
C194  Probe Info			32.00	LDD1870	[11]
C195  Probe Info			5.17	LDD1871	[11]
C196  Probe Info			24.93	LDD1872	[11]
C197  Probe Info			6.02	LDD1873	[11]
C198  Probe Info			29.24	LDD1874	[11]
C201  Probe Info			77.71	LDD1877	[11]
C204  Probe Info			5.70	LDD1879	[11]
C206  Probe Info			39.40	LDD1881	[11]
C210  Probe Info			90.51	LDD1884	[11]
C211  Probe Info			20.25	LDD1885	[11]
C212  Probe Info			7.31	LDD1886	[11]
C213  Probe Info			44.32	LDD1887	[11]
C214  Probe Info			11.96	LDD1888	[11]
C216  Probe Info			6.02	LDD1890	[11]
C217  Probe Info			4.96	LDD1891	[11]
C218  Probe Info			47.18	LDD1892	[11]
C219  Probe Info			36.00	LDD1893	[11]
C220  Probe Info			58.89	LDD1894	[11]
C225  Probe Info			8.34	LDD1898	[11]
C226  Probe Info			13.18	LDD1899	[11]
C228  Probe Info			46.85	LDD1901	[11]
C229  Probe Info			24.08	LDD1902	[11]
C231  Probe Info			99.73	LDD1904	[11]
C232  Probe Info			88.03	LDD1905	[11]
C233  Probe Info			46.53	LDD1906	[11]
C234  Probe Info			21.86	LDD1907	[11]
C235  Probe Info			40.79	LDD1908	[11]
C238  Probe Info			27.28	LDD1911	[11]
C240  Probe Info			20.11	LDD1913	[11]
C243  Probe Info			34.54	LDD1916	[11]
C244  Probe Info			21.86	LDD1917	[11]
C246  Probe Info			52.71	LDD1919	[11]
C249  Probe Info			15.56	LDD1922	[11]
C251  Probe Info			26.17	LDD1924	[11]
C252  Probe Info			19.97	LDD1925	[11]
C255  Probe Info			5.35	LDD1928	[11]
C258  Probe Info			5.39	LDD1931	[11]
C260  Probe Info			7.01	LDD1932	[11]
C264  Probe Info			56.89	LDD1935	[11]
C265  Probe Info			47.84	LDD1936	[11]
C269  Probe Info			11.39	LDD1939	[11]
C270  Probe Info			12.47	LDD1940	[11]
C273  Probe Info			5.54	LDD1943	[11]
C277  Probe Info			64.89	LDD1947	[11]
C278  Probe Info			47.50	LDD1948	[11]
C280  Probe Info			8.82	LDD1950	[11]
C282  Probe Info			37.79	LDD1952	[11]
C284  Probe Info			73.01	LDD1954	[11]
C285  Probe Info			41.36	LDD1955	[11]
C287  Probe Info			19.56	LDD1957	[11]
C288  Probe Info			19.03	LDD1958	[11]
C289  Probe Info			67.65	LDD1959	[11]
C290  Probe Info			6.87	LDD1960	[11]
C292  Probe Info			6.32	LDD1962	[11]
C293  Probe Info			53.82	LDD1963	[11]
C296  Probe Info			28.25	LDD1966	[11]
C299  Probe Info			12.47	LDD1968	[11]
C300  Probe Info			5.17	LDD1969	[11]
C301  Probe Info			9.58	LDD1970	[11]
C305  Probe Info			22.78	LDD1974	[11]
C310  Probe Info			34.54	LDD1977	[11]
C313  Probe Info			17.03	LDD1980	[11]
C314  Probe Info			32.90	LDD1981	[11]
C317  Probe Info			13.18	LDD1983	[11]
C322  Probe Info			7.21	LDD1988	[11]
C326  Probe Info			22.94	LDD1990	[11]
C333  Probe Info			9.13	LDD1996	[11]
C337  Probe Info			15.67	LDD2000	[11]
C338  Probe Info			22.47	LDD2001	[11]
C339  Probe Info			10.93	LDD2002	[11]
C343  Probe Info			38.59	LDD2005	[11]
C348  Probe Info			15.56	LDD2009	[11]
C349  Probe Info			38.85	LDD2010	[11]
C350  Probe Info			99.73	LDD2011	[11]
C353  Probe Info			11.31	LDD2014	[11]
C354  Probe Info			13.55	LDD2015	[11]
C355  Probe Info			45.89	LDD2016	[11]
C356  Probe Info			53.08	LDD2017	[11]
C357  Probe Info			14.72	LDD2018	[11]
C360  Probe Info			8.17	LDD2021	[11]
C362  Probe Info			82.71	LDD2023	[11]
C363  Probe Info			35.75	LDD2024	[11]
C364  Probe Info			30.91	LDD2025	[11]
C366  Probe Info			12.64	LDD2027	[11]
C367  Probe Info			7.52	LDD2028	[11]
C373  Probe Info			9.51	LDD2033	[11]
C376  Probe Info			11.71	LDD2036	[11]
C380  Probe Info			5.78	LDD2039	[11]
C382  Probe Info			15.78	LDD2041	[11]
C386  Probe Info			18.25	LDD2045	[11]
C387  Probe Info			6.96	LDD2046	[11]
C388  Probe Info			92.41	LDD2047	[11]
C390  Probe Info			63.12	LDD2049	[11]
C391  Probe Info			14.72	LDD2050	[11]
C393  Probe Info			6.23	LDD2052	[11]
C399  Probe Info			11.55	LDD2058	[11]
C403  Probe Info			30.70	LDD2061	[11]
C407  Probe Info			17.88	LDD2064	[11]
C413  Probe Info			44.02	LDD2069	[11]
C414  Probe Info			11.00	LDD2070	[11]
C416  Probe Info			6.63	LDD2071	[11]
C419  Probe Info			23.10	LDD2074	[11]
C420  Probe Info			20.53	LDD2075	[11]
C422  Probe Info			29.04	LDD2077	[11]
C424  Probe Info			16.22	LDD2079	[11]
C426  Probe Info			17.03	LDD2081	[11]
C428  Probe Info			18.13	LDD2083	[11]
C429  Probe Info			56.10	LDD2084	[11]
C431  Probe Info			91.14	LDD2086	[11]
C433  Probe Info			7.52	LDD2088	[11]
FFF probe14  Probe Info			20.00	LDD0477	[12]
FFF probe2  Probe Info			20.00	LDD0463	[12]
STS-1  Probe Info			N.A.	LDD0136	[13]
STS-2  Probe Info			N.A.	LDD0139	[13]

Competitor ID	Name	Cell line	Binding Site(Ratio)	Interaction ID	Ref
LDCM0214	AC1	HEK-293T	C81(1.09)	LDD1507	[14]
LDCM0215	AC10	HEK-293T	C81(1.15)	LDD1508	[14]
LDCM0226	AC11	HEK-293T	C81(0.95)	LDD1509	[14]
LDCM0237	AC12	HEK-293T	C81(0.88)	LDD1510	[14]
LDCM0270	AC15	HEK-293T	C81(1.15)	LDD1513	[14]
LDCM0276	AC17	HEK-293T	C81(1.11)	LDD1515	[14]
LDCM0277	AC18	HEK-293T	C81(1.14)	LDD1516	[14]
LDCM0278	AC19	HEK-293T	C81(0.98)	LDD1517	[14]
LDCM0279	AC2	HEK-293T	C81(1.19)	LDD1518	[14]
LDCM0280	AC20	HEK-293T	C81(0.92)	LDD1519	[14]
LDCM0281	AC21	HEK-293T	C81(0.99)	LDD1520	[14]
LDCM0283	AC23	HEK-293T	C81(0.93)	LDD1522	[14]
LDCM0284	AC24	HEK-293T	C81(0.92)	LDD1523	[14]
LDCM0285	AC25	HEK-293T	C81(0.90)	LDD1524	[14]
LDCM0286	AC26	HEK-293T	C81(1.69)	LDD1525	[14]
LDCM0287	AC27	HEK-293T	C81(1.03)	LDD1526	[14]
LDCM0288	AC28	HEK-293T	C81(0.88)	LDD1527	[14]
LDCM0289	AC29	HEK-293T	C81(1.11)	LDD1528	[14]
LDCM0290	AC3	HEK-293T	C81(0.73)	LDD1529	[14]
LDCM0292	AC31	HEK-293T	C81(0.90)	LDD1531	[14]
LDCM0293	AC32	HEK-293T	C81(0.95)	LDD1532	[14]
LDCM0294	AC33	HEK-293T	C81(0.97)	LDD1533	[14]
LDCM0295	AC34	HEK-293T	C81(0.88)	LDD1534	[14]
LDCM0296	AC35	HEK-293T	C81(0.81)	LDD1535	[14]
LDCM0297	AC36	HEK-293T	C81(1.06)	LDD1536	[14]
LDCM0298	AC37	HEK-293T	C81(0.87)	LDD1537	[14]
LDCM0300	AC39	HEK-293T	C81(1.11)	LDD1539	[14]
LDCM0301	AC4	HEK-293T	C81(1.02)	LDD1540	[14]
LDCM0302	AC40	HEK-293T	C81(0.79)	LDD1541	[14]
LDCM0303	AC41	HEK-293T	C81(1.07)	LDD1542	[14]
LDCM0304	AC42	HEK-293T	C81(1.11)	LDD1543	[14]
LDCM0305	AC43	HEK-293T	C81(0.89)	LDD1544	[14]
LDCM0306	AC44	HEK-293T	C81(0.82)	LDD1545	[14]
LDCM0307	AC45	HEK-293T	C81(1.04)	LDD1546	[14]
LDCM0309	AC47	HEK-293T	C81(1.24)	LDD1548	[14]
LDCM0310	AC48	HEK-293T	C81(0.79)	LDD1549	[14]
LDCM0311	AC49	HEK-293T	C81(1.01)	LDD1550	[14]
LDCM0312	AC5	HEK-293T	C81(1.04)	LDD1551	[14]
LDCM0313	AC50	HEK-293T	C81(1.13)	LDD1552	[14]
LDCM0314	AC51	HEK-293T	C81(0.73)	LDD1553	[14]
LDCM0315	AC52	HEK-293T	C81(0.77)	LDD1554	[14]
LDCM0316	AC53	HEK-293T	C81(0.86)	LDD1555	[14]
LDCM0318	AC55	HEK-293T	C81(1.00)	LDD1557	[14]
LDCM0319	AC56	HEK-293T	C81(1.07)	LDD1558	[14]
LDCM0320	AC57	HEK-293T	C81(1.02)	LDD1559	[14]
LDCM0321	AC58	HEK-293T	C81(1.02)	LDD1560	[14]
LDCM0322	AC59	HEK-293T	C81(0.86)	LDD1561	[14]
LDCM0324	AC60	HEK-293T	C81(1.09)	LDD1563	[14]
LDCM0325	AC61	HEK-293T	C81(0.97)	LDD1564	[14]
LDCM0327	AC63	HEK-293T	C81(1.09)	LDD1566	[14]
LDCM0328	AC64	HEK-293T	C81(0.86)	LDD1567	[14]
LDCM0334	AC7	HEK-293T	C81(1.20)	LDD1568	[14]
LDCM0345	AC8	HEK-293T	C81(0.92)	LDD1569	[14]
LDCM0248	AKOS034007472	HEK-293T	C81(1.11)	LDD1511	[14]
LDCM0356	AKOS034007680	HEK-293T	C81(1.08)	LDD1570	[14]
LDCM0275	AKOS034007705	HEK-293T	C81(0.92)	LDD1514	[14]
LDCM0367	CL1	HEK-293T	C81(1.16)	LDD1571	[14]
LDCM0369	CL100	HEK-293T	C81(0.76)	LDD1573	[14]
LDCM0370	CL101	HEK-293T	C81(1.21)	LDD1574	[14]
LDCM0371	CL102	HEK-293T	C81(0.85)	LDD1575	[14]
LDCM0373	CL104	HEK-293T	C81(1.09)	LDD1577	[14]
LDCM0374	CL105	HEK-293T	C81(1.17)	LDD1578	[14]
LDCM0375	CL106	HEK-293T	C81(0.98)	LDD1579	[14]
LDCM0377	CL108	HEK-293T	C81(1.14)	LDD1581	[14]
LDCM0378	CL109	HEK-293T	C81(1.37)	LDD1582	[14]
LDCM0379	CL11	HEK-293T	C81(1.22)	LDD1583	[14]
LDCM0380	CL110	HEK-293T	C81(1.01)	LDD1584	[14]
LDCM0382	CL112	HEK-293T	C81(1.11)	LDD1586	[14]
LDCM0383	CL113	HEK-293T	C81(1.13)	LDD1587	[14]
LDCM0384	CL114	HEK-293T	C81(1.41)	LDD1588	[14]
LDCM0386	CL116	HEK-293T	C81(0.80)	LDD1590	[14]
LDCM0387	CL117	HEK-293T	C81(1.02)	LDD1591	[14]
LDCM0388	CL118	HEK-293T	C81(1.14)	LDD1592	[14]
LDCM0390	CL12	HEK-293T	C81(0.43)	LDD1594	[14]
LDCM0391	CL120	HEK-293T	C81(1.12)	LDD1595	[14]
LDCM0392	CL121	HEK-293T	C81(1.03)	LDD1596	[14]
LDCM0393	CL122	HEK-293T	C81(1.18)	LDD1597	[14]
LDCM0395	CL124	HEK-293T	C81(1.02)	LDD1599	[14]
LDCM0396	CL125	HEK-293T	C81(1.34)	LDD1600	[14]
LDCM0397	CL126	HEK-293T	C81(1.10)	LDD1601	[14]
LDCM0399	CL128	HEK-293T	C81(2.11)	LDD1603	[14]
LDCM0400	CL13	HEK-293T	C81(1.05)	LDD1604	[14]
LDCM0401	CL14	HEK-293T	C81(1.01)	LDD1605	[14]
LDCM0403	CL16	HEK-293T	C81(0.69)	LDD1607	[14]
LDCM0404	CL17	HEK-293T	C81(1.28)	LDD1608	[14]
LDCM0405	CL18	HEK-293T	C81(1.20)	LDD1609	[14]
LDCM0406	CL19	HEK-293T	C81(0.75)	LDD1610	[14]
LDCM0407	CL2	HEK-293T	C81(1.10)	LDD1611	[14]
LDCM0408	CL20	HEK-293T	C81(0.81)	LDD1612	[14]
LDCM0409	CL21	HEK-293T	C81(0.83)	LDD1613	[14]
LDCM0411	CL23	HEK-293T	C81(1.12)	LDD1615	[14]
LDCM0412	CL24	HEK-293T	C81(1.02)	LDD1616	[14]
LDCM0413	CL25	HEK-293T	C81(1.47)	LDD1617	[14]
LDCM0414	CL26	HEK-293T	C81(1.35)	LDD1618	[14]
LDCM0416	CL28	HEK-293T	C81(0.81)	LDD1620	[14]
LDCM0417	CL29	HEK-293T	C81(0.98)	LDD1621	[14]
LDCM0419	CL30	HEK-293T	C81(1.14)	LDD1623	[14]
LDCM0420	CL31	HEK-293T	C81(0.90)	LDD1624	[14]
LDCM0421	CL32	HEK-293T	C81(0.84)	LDD1625	[14]
LDCM0422	CL33	HEK-293T	C81(1.16)	LDD1626	[14]
LDCM0424	CL35	HEK-293T	C81(1.04)	LDD1628	[14]
LDCM0425	CL36	HEK-293T	C81(0.74)	LDD1629	[14]
LDCM0426	CL37	HEK-293T	C81(1.15)	LDD1630	[14]
LDCM0429	CL4	HEK-293T	C81(1.18)	LDD1633	[14]
LDCM0430	CL40	HEK-293T	C81(1.12)	LDD1634	[14]
LDCM0431	CL41	HEK-293T	C81(0.99)	LDD1635	[14]
LDCM0432	CL42	HEK-293T	C81(0.97)	LDD1636	[14]
LDCM0433	CL43	HEK-293T	C81(0.65)	LDD1637	[14]
LDCM0434	CL44	HEK-293T	C81(0.83)	LDD1638	[14]
LDCM0435	CL45	HEK-293T	C81(1.18)	LDD1639	[14]
LDCM0437	CL47	HEK-293T	C81(1.09)	LDD1641	[14]
LDCM0438	CL48	HEK-293T	C81(0.94)	LDD1642	[14]
LDCM0439	CL49	HEK-293T	C81(1.22)	LDD1643	[14]
LDCM0440	CL5	HEK-293T	C81(0.96)	LDD1644	[14]
LDCM0441	CL50	HEK-293T	C81(0.91)	LDD1645	[14]
LDCM0443	CL52	HEK-293T	C81(1.03)	LDD1646	[14]
LDCM0444	CL53	HEK-293T	C81(1.34)	LDD1647	[14]
LDCM0445	CL54	HEK-293T	C81(1.56)	LDD1648	[14]
LDCM0446	CL55	HEK-293T	C81(0.82)	LDD1649	[14]
LDCM0447	CL56	HEK-293T	C81(0.83)	LDD1650	[14]
LDCM0448	CL57	HEK-293T	C81(1.14)	LDD1651	[14]
LDCM0450	CL59	HEK-293T	C81(1.09)	LDD1653	[14]
LDCM0451	CL6	HEK-293T	C81(1.23)	LDD1654	[14]
LDCM0452	CL60	HEK-293T	C81(0.95)	LDD1655	[14]
LDCM0453	CL61	HEK-293T	C81(1.05)	LDD1656	[14]
LDCM0454	CL62	HEK-293T	C81(1.01)	LDD1657	[14]
LDCM0456	CL64	HEK-293T	C81(1.27)	LDD1659	[14]
LDCM0457	CL65	HEK-293T	C81(0.99)	LDD1660	[14]
LDCM0458	CL66	HEK-293T	C81(1.08)	LDD1661	[14]
LDCM0459	CL67	HEK-293T	C81(0.76)	LDD1662	[14]
LDCM0460	CL68	HEK-293T	C81(0.76)	LDD1663	[14]
LDCM0461	CL69	HEK-293T	C81(0.96)	LDD1664	[14]
LDCM0462	CL7	HEK-293T	C81(0.66)	LDD1665	[14]
LDCM0464	CL71	HEK-293T	C81(1.00)	LDD1667	[14]
LDCM0465	CL72	HEK-293T	C81(0.95)	LDD1668	[14]
LDCM0466	CL73	HEK-293T	C81(1.17)	LDD1669	[14]
LDCM0467	CL74	HEK-293T	C81(0.86)	LDD1670	[14]
LDCM0469	CL76	HEK-293T	C81(0.74)	LDD1672	[14]
LDCM0470	CL77	HEK-293T	C81(1.00)	LDD1673	[14]
LDCM0471	CL78	HEK-293T	C81(0.77)	LDD1674	[14]
LDCM0472	CL79	HEK-293T	C81(0.75)	LDD1675	[14]
LDCM0473	CL8	HEK-293T	C81(1.00)	LDD1676	[14]
LDCM0474	CL80	HEK-293T	C81(0.74)	LDD1677	[14]
LDCM0475	CL81	HEK-293T	C81(0.96)	LDD1678	[14]
LDCM0477	CL83	HEK-293T	C81(1.17)	LDD1680	[14]
LDCM0478	CL84	HEK-293T	C81(0.81)	LDD1681	[14]
LDCM0479	CL85	HEK-293T	C81(1.17)	LDD1682	[14]
LDCM0480	CL86	HEK-293T	C81(1.66)	LDD1683	[14]
LDCM0482	CL88	HEK-293T	C81(1.00)	LDD1685	[14]
LDCM0483	CL89	HEK-293T	C81(1.01)	LDD1686	[14]
LDCM0484	CL9	HEK-293T	C81(1.09)	LDD1687	[14]
LDCM0485	CL90	HEK-293T	C81(1.39)	LDD1688	[14]
LDCM0486	CL91	HEK-293T	C81(0.74)	LDD1689	[14]
LDCM0487	CL92	HEK-293T	C81(0.88)	LDD1690	[14]
LDCM0488	CL93	HEK-293T	C81(1.08)	LDD1691	[14]
LDCM0490	CL95	HEK-293T	C81(1.54)	LDD1693	[14]
LDCM0491	CL96	HEK-293T	C81(1.08)	LDD1694	[14]
LDCM0492	CL97	HEK-293T	C81(1.22)	LDD1695	[14]
LDCM0493	CL98	HEK-293T	C81(0.84)	LDD1696	[14]
LDCM0427	Fragment51	HEK-293T	C81(0.99)	LDD1631	[14]
LDCM0179	JZ128	PC-3	N.A.	LDD0462	[6]
LDCM0022	KB02	CAL-120	C182(1.10)	LDD2284	[5]
LDCM0023	KB03	EFO-27	C199(2.52)	LDD2739	[5]
LDCM0024	KB05	HMCB	C182(0.97)	LDD3312	[5]

Protein name				Family	Uniprot ID
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (AGPAT4)				1-acyl-sn-glycerol-3-phosphate acyltransferase family	Q9NRZ5
Lysophosphatidylcholine acyltransferase 2 (LPCAT2)				1-acyl-sn-glycerol-3-phosphate acyltransferase family	Q7L5N7
Phosphatidylserine lipase ABHD16A (ABHD16A)				ABHD16 family	O95870
Antigen peptide transporter 1 (TAP1)				ABCB family	Q03518
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase (ALG10)				ALG10 glucosyltransferase family	Q5BKT4
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT)				CDP-alcohol phosphatidyltransferase class-I family	O14735
Phosphatidate cytidylyltransferase 2 (CDS2)				CDS family	O95674
NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6)				Complex I NDUFB6 subunit family	O95139
Amine oxidase [copper-containing] 2 (AOC2)				Copper/topaquinone oxidase family	O75106
Cytochrome P450 4F2 (CYP4F2)				Cytochrome P450 family	P78329
Palmitoyltransferase ZDHHC15 (ZDHHC15)				DHHC palmitoyltransferase family	Q96MV8
Palmitoyltransferase ZDHHC21 (ZDHHC21)				DHHC palmitoyltransferase family	Q8IVQ6
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP)				EBP family	Q15125
Peroxisomal bifunctional enzyme (EHHADH)				Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase family	Q08426
Stearoyl-CoA desaturase (SCD)				Fatty acid desaturase type 1 family	O00767
Sialidase-1 (NEU1)				Glycosyl hydrolase 33 family	Q99519
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGNT1)				Glycosyltransferase 13 family	Q8WZA1
Exostosin-like 1 (EXTL1)				Glycosyltransferase 47 family	Q92935
Heme oxygenase 1 (HMOX1)				Heme oxygenase family	P09601
Heme oxygenase 2 (HMOX2)				Heme oxygenase family	P30519
Protein-cysteine N-palmitoyltransferase HHAT-like protein (HHATL)				Membrane-bound acyltransferase family	Q9HCP6
MYG1 exonuclease (MYG1)				MYG1 family	Q9HB07
Phospholipid phosphatase 4 (PLPP4)				PA-phosphatase related phosphoesterase family	Q5VZY2
Complement C2 (C2)				Peptidase S1 family	P06681
Very-long-chain enoyl-CoA reductase (TECR)				Steroid 5-alpha reductase family	Q9NZ01
Fatty acid hydroxylase domain-containing protein 2 (FAXDC2)				Sterol desaturase family	Q96IV6
Fatty acid 2-hydroxylase (FA2H)				Sterol desaturase family	Q7L5A8
Lysoplasmalogenase TMEM86A (TMEM86A)				TMEM86 family	Q8N2M4
Lysoplasmalogenase TMEM86B (TMEM86B)				TMEM86 family	Q8N661
GTPase IMAP family member 1 (GIMAP1)				AIG1/Toc34/Toc159-like paraseptin GTPase family	Q8WWP7
GTPase IMAP family member 5 (GIMAP5)				AIG1/Toc34/Toc159-like paraseptin GTPase family	Q96F15
E3 ubiquitin-protein ligase TRIM32 (TRIM32)				TRIM/RBCC family	Q13049
UbiA prenyltransferase domain-containing protein 1 (UBIAD1)				UbiA prenyltransferase family	Q9Y5Z9
Ubiquitin-conjugating enzyme E2 J1 (UBE2J1)				Ubiquitin-conjugating enzyme family	Q9Y385
V-type proton ATPase 16 kDa proteolipid subunit c (ATP6V0C)				V-ATPase proteolipid subunit family	P27449
Vitamin K epoxide reductase complex subunit 1 (VKORC1)				VKOR family	Q9BQB6
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1)				VKOR family	Q8N0U8
E3 ubiquitin-protein ligase MARCHF2 (MARCHF2)				.	Q9P0N8
E3 ubiquitin-protein ligase MARCHF5 (MARCHF5)				.	Q9NX47
Peptidyl-prolyl cis-trans isomerase FKBP8 (FKBP8)				.	Q14318
Transmembrane ascorbate-dependent reductase CYB561 (CYB561)				.	P49447
Transmembrane reductase CYB561D2 (CYB561D2)				.	O14569

Protein name				Family	Uniprot ID
Sodium-coupled neutral amino acid transporter 7 (SLC38A7)				Amino acid/polyamine transporter 2 family	Q9NVC3
Ammonium transporter Rh type A (RHAG)				Ammonium transporter family	Q02094
Bcl-2-like protein 1 (BCL2L1)				Bcl-2 family	Q07817
Bcl-2-like protein 2 (BCL2L2)				Bcl-2 family	Q92843
Beta-defensin 103 (DEFB103A; DEFB103B)				Beta-defensin family	P81534
Proton-coupled zinc antiporter SLC30A8 (SLC30A8)				Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	Q8IWU4
Interferon-induced transmembrane protein 3 (IFITM3)				CD225/Dispanin family	Q01628
Lysosome membrane protein 2 (SCARB2)				CD36 family	Q14108
Claudin-8 (CLDN8)				Claudin family	P56748
Gap junction beta-2 protein (GJB2)				Connexin family	P29033
Protein cornichon homolog 1 (CNIH1)				Cornichon family	O95406
Protein cornichon homolog 3 (CNIH3)				Cornichon family	Q8TBE1
Cytochrome c oxidase assembly protein COX20, mitochondrial (COX20)				COX20 family	Q5RI15
Excitatory amino acid transporter 3 (SLC1A1)				Dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family	P43005
ER membrane protein complex subunit 6 (EMC6)				EMC6 family	Q9BV81
FXYD domain-containing ion transport regulator 6 (FXYD6)				FXYD family	Q9H0Q3
Glycophorin-A (GYPA)				Glycophorin A family	P02724
Statherin (STATH)				Histatin/statherin family	P02808
Transmembrane 4 L6 family member 4 (TM4SF4)				L6 tetraspanin family	P48230
LHFPL tetraspan subfamily member 5 protein (LHFPL5)				LHFP family	Q8TAF8
Major facilitator superfamily domain-containing protein 6 (MFSD6)				MFSD6 family	Q6ZSS7
Myeloid-associated differentiation marker (MYADM)				MAL family	Q96S97
Aquaporin-10 (AQP10)				MIP/aquaporin (TC 1.A.8) family	Q96PS8
Aquaporin-2 (AQP2)				MIP/aquaporin (TC 1.A.8) family	P41181
Aquaporin-3 (AQP3)				MIP/aquaporin (TC 1.A.8) family	Q92482
Lens fiber major intrinsic protein (MIP)				MIP/aquaporin (TC 1.A.8) family	P30301
Membrane-spanning 4-domains subfamily A member 13 (MS4A13)				MS4A family	Q5J8X5
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3)				NIP3 family	Q12983
CMP-sialic acid transporter (SLC35A1)				Nucleotide-sugar transporter family	P78382
Probable UDP-sugar transporter protein SLC35A4 (SLC35A4)				Nucleotide-sugar transporter family	Q96G79
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2)				Nucleotide-sugar transporter family	Q8TB61
Nucleotide sugar transporter SLC35B4 (SLC35B4)				Nucleotide-sugar transporter family	Q969S0
Haptoglobin (HP)				Peptidase S1 family	P00738
Peroxisomal membrane protein PEX16 (PEX16)				Peroxin-16 family	Q9Y5Y5
Peripheral myelin protein 22 (PMP22)				PMP-22/EMP/MP20 family	Q01453
Protein RFT1 homolog (RFT1)				RFT1 family	Q96AA3
Na(+)/dicarboxylate cotransporter 3 (SLC13A3)				SLC13A/DASS transporter family	Q8WWT9
Solute carrier family 41 member 1 (SLC41A1)				SLC41A transporter family	Q8IVJ1
Solute carrier family 41 member 2 (SLC41A2)				SLC41A transporter family	Q96JW4
Small integral membrane protein 1 (SMIM1)				SMIM1 family	B2RUZ4
Vesicle-associated membrane protein 2 (VAMP2)				Synaptobrevin family	P63027
Vesicle-associated membrane protein 3 (VAMP3)				Synaptobrevin family	Q15836
Syntaxin-3 (STX3)				Syntaxin family	Q13277
CD81 antigen (CD81)				Tetraspanin (TM4SF) family	P60033
Tetraspanin-33 (TSPAN33)				Tetraspanin (TM4SF) family	Q86UF1
Transmembrane protein 14A (TMEM14A)				TMEM14 family	Q9Y6G1
Transmembrane protein 14B (TMEM14B)				TMEM14 family	Q9NUH8
Transmembrane protein 179B (TMEM179B)				TMEM179 family	Q7Z7N9
Transmembrane protein 218 (TMEM218)				TMEM218 family	A2RU14
Sigma intracellular receptor 2 (TMEM97)				TMEM97/sigma-2 receptor family	Q5BJF2
Translocating chain-associated membrane protein 1-like 1 (TRAM1L1)				TRAM family	Q8N609
Translocator protein 2 (TSPO2)				TspO/BZRP family	Q5TGU0
Potassium channel subfamily K member 1 (KCNK1)				Two pore domain potassium channel (TC 1.A.1.8) family	O00180
Protein unc-93 homolog B1 (UNC93B1)				Unc-93 family	Q9H1C4
Vacuole membrane protein 1 (VMP1)				VMP1 family	Q96GC9
Vesicle transport through interaction with t-SNAREs homolog 1B (VTI1B)				VTI1 family	Q9UEU0
Protein YIPF1 (YIPF1)				YIP1 family	Q9Y548
Protein YIPF2 (YIPF2)				YIP1 family	Q9BWQ6
Phospholipid transfer protein C2CD2L (C2CD2L)				.	O14523
Synaptojanin-2-binding protein (SYNJ2BP)				.	P57105
Transmembrane protein 100 (TMEM100)				.	Q9NV29
Transmembrane protein 203 (TMEM203)				.	Q969S6
Transmembrane protein 60 (TMEM60)				.	Q9H2L4
Transmembrane protein 65 (TMEM65)				.	Q6PI78
Voltage-gated monoatomic cation channel TMEM109 (TMEM109)				.	Q9BVC6

Protein name				Family	Uniprot ID
Membrane progestin receptor alpha (PAQR7)				ADIPOR family	Q86WK9
Membrane progestin receptor gamma (PAQR5)				ADIPOR family	Q9NXK6
G-protein coupled receptor 151 (GPR151)				G-protein coupled receptor 1 family	Q8TDV0
Lysophosphatidic acid receptor 3 (LPAR3)				G-protein coupled receptor 1 family	Q9UBY5

Protein name				Family	Uniprot ID
Butyrophilin subfamily 2 member A2 (BTN2A2)				BTN/MOG family	Q8WVV5

Protein name				Family	Uniprot ID
Tumor necrosis factor receptor superfamily member 10C (TNFRSF10C)				.	O14798

Protein name				Family	Uniprot ID
Apolipoprotein C-III (APOC3)				Apolipoprotein C3 family	P02656
Apolipoprotein L2 (APOL2)				Apolipoprotein L family	Q9BQE5
BET1 homolog (BET1)				BET1 family	O15155
Apolipoprotein D (APOD)				Lipocalin family	P05090
Cortexin-3 (CTXN3)				Cortexin family	Q4LDR2
Cytochrome b-245 chaperone 1 (CYBC1)				CYBC1 family	Q9BQA9
Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1)				ERGIC family	Q969X5
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2)				ERGIC family	Q96RQ1
Protein FAM3C (FAM3C)				FAM3 family	Q92520
Fetuin-B (FETUB)				Fetuin family	Q9UGM5
Mitochondrial fission 1 protein (FIS1)				FIS1 family	Q9Y3D6
Gastrin (GAST)				Gastrin/cholecystokinin family	P01350
Integrin alpha-M (ITGAM)				Integrin alpha chain family	P11215
Protein jagunal homolog 1 (JAGN1)				Jagunal family	Q8N5M9
Plasmolipin (PLLP)				MAL family	Q9Y342
Cytosolic iron-sulfur assembly component 2A (CIAO2A)				MIP18 family	Q9H5X1
Pro-neuregulin-4, membrane-bound isoform (NRG4)				Neuregulin family	Q8WWG1
Ninjurin-2 (NINJ2)				Ninjurin family	Q9NZG7
Neuronal vesicle trafficking-associated protein 1 (NSG1)				NSG family	P42857
Nurim (NRM)				Nurim family	Q8IXM6
ORM1-like protein 1 (ORMDL1)				ORM family	Q9P0S3
ORM1-like protein 3 (ORMDL3)				ORM family	Q8N138
Peroxisomal membrane protein 11C (PEX11G)				Peroxin-11 family	Q96HA9
Claudin domain-containing protein 2 (CLDND2)				PMP-22/EMP/MP20 family	Q8NHS1
Epithelial membrane protein 1 (EMP1)				PMP-22/EMP/MP20 family	P54849
Epithelial membrane protein 3 (EMP3)				PMP-22/EMP/MP20 family	P54852
Protein NKG7 (NKG7)				PMP-22/EMP/MP20 family	Q16617
Stress-associated endoplasmic reticulum protein 2 (SERP2)				RAMP4 family	Q8N6R1
RUS family member 1 (RUSF1)				RUS1 family	Q96GQ5
Protein transport protein Sec23A (SEC23A)				SEC23/SEC24 family	Q15436
Selenoprotein K (SELENOK)				Selenoprotein K family	Q9Y6D0
Alpha-1-antitrypsin (SERPINA1)				Serpin family	P01009
Sideroflexin-5 (SFXN5)				Sideroflexin family	Q8TD22
Small cell adhesion glycoprotein (SMAGP)				SMAGP family	Q0VAQ4
Single-pass membrane and coiled-coil domain-containing protein 4 (SMCO4)				SMCO4 family	Q9NRQ5
Vesicle-associated membrane protein 4 (VAMP4)				Synaptobrevin family	O75379
Vesicle-associated membrane protein 5 (VAMP5)				Synaptobrevin family	O95183
Vesicle-trafficking protein SEC22b (SEC22B)				Synaptobrevin family	O75396
Syntaxin-12 (STX12)				Syntaxin family	Q86Y82
Syntaxin-1B (STX1B)				Syntaxin family	P61266
Syntaxin-8 (STX8)				Syntaxin family	Q9UNK0
Protein SYS1 homolog (SYS1)				SYS1 family	Q8N2H4
Transmembrane protein 120B (TMEM120B)				TMEM120 family	A0PK00
Transmembrane protein 141 (TMEM141)				TMEM141 family	Q96I45
Transmembrane protein 229B (TMEM229B)				TMEM229 family	Q8NBD8
Transmembrane protein 243 (TMEM243)				TMEM243 family	Q9BU79
Receptor-transporting protein 2 (RTP2)				TMEM7 family	Q5QGT7
Mitochondrial import receptor subunit TOM6 homolog (TOMM6)				Tom6 family	Q96B49
Serotransferrin (TF)				Transferrin family	P02787
Protein unc-50 homolog (UNC50)				Unc-50 family	Q53HI1
Protein YIF1A (YIF1A)				YIF1 family	O95070
Protein YIPF4 (YIPF4)				YIP1 family	Q9BSR8
Protein YIPF6 (YIPF6)				YIP1 family	Q96EC8
Zinc finger protein-like 1 (ZFPL1)				ZFPL1 family	O95159
Asialoglycoprotein receptor 1 (ASGR1)				.	P07306
Bcl-2-interacting killer (BIK)				.	Q13323
C-type lectin domain family 4 member K (CD207)				.	Q9UJ71
CD302 antigen (CD302)				.	Q8IX05
Coiled-coil domain-containing protein 167 (CCDC167)				.	Q9P0B6
Complement factor H-related protein 5 (CFHR5)				.	Q9BXR6
Insulin-like growth factor-binding protein 5 (IGFBP5)				.	P24593
Leukosialin (SPN)				.	P16150
Nutritionally-regulated adipose and cardiac enriched protein homolog (NRAC)				.	Q8N912
Protein SNORC (SNORC)				.	Q6UX34
Small integral membrane protein 3 (SMIM3)				.	Q9BZL3
Thrombomodulin (THBD)				.	P07204
TPA-induced transmembrane protein (TTMP)				.	Q5BVD1
Transmembrane and ubiquitin-like domain-containing protein 2 (TMUB2)				.	Q71RG4
Transmembrane protein 107 (TMEM107)				.	Q6UX40
Transmembrane protein 222 (TMEM222)				.	Q9H0R3
Transmembrane protein 42 (TMEM42)				.	Q69YG0
Uncharacterized protein CXorf66 (CXorf66)				.	Q5JRM2

1	Charting the Chemical Space of Acrylamide-Based Inhibitors of zDHHC20. ACS Med Chem Lett. 2022 Sep 26;13(10):1648-1654. doi: 10.1021/acsmedchemlett.2c00336. eCollection 2022 Oct 13.
2	Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
3	A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10. Mass spectrometry data entry: PXD028270
4	An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
5	DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22. Mass spectrometry data entry: PXD047840
6	A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification. J Am Chem Soc. 2019 Jan 9;141(1):191-203. doi: 10.1021/jacs.8b07911. Epub 2018 Dec 20.
7	Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print. Mass spectrometry data entry: PXD042377
8	Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23. Mass spectrometry data entry: PXD028853
9	Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
10	N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w. Mass spectrometry data entry: PXD041264
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