Details of the Probe

General Information of Probe

Probe ID
LDPC0464
Probe Name
C231
Synonyms
Z4282859782
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 347.5
Lipid-water partition coefficient (xlogp) 3.7
Rotatable Bond Count (rotbonds) 9
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C20H33N3O2
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[2-hydroxy-2-(4-propan-2-ylcyclohexyl)propyl]propanamide
Canonical SMILES
CC(C)C1CCC(CC1)C(C)(CNC(=O)CCC2(N=N2)CCC#C)O
InChI
InChI=1S/C20H33N3O2/c1-5-6-12-20(22-23-20)13-11-18(24)21-14-19(4,25)17-9-7-16(8-10-17)15(2)3/h1,15-17,25H,6-14H2,2-4H3,(H,21,24)
InChIKey
ABBUKZXNNXAJSJ-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

170 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 11.96  LDD1904 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 32.45  LDD1904 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 11.39  LDD1904 
7-dehydrocholesterol reductase (DHCR7) LDTP13131 13.00  LDD1904 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 11.71  LDD1904 
Acid ceramidase (ASAH1) LDTP05905 20.39  LDD1904 
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) LDTP09814 19.29  LDD1904 
Adenosine 5'-monophosphoramidase HINT3 (HINT3) LDTP12415 54.95  LDD1904 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 12.30  LDD1904 
ADP-dependent glucokinase (ADPGK) LDTP11127 15.03  LDD1904 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 15.03  LDD1904 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 28.84  LDD1904 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 17.75  LDD1904 
Antigen peptide transporter 1 (TAP1) LDTP05408 11.79  LDD1904 
Atlastin-2 (ATL2) LDTP09251 33.36  LDD1904 
ATP synthase membrane subunit K, mitochondrial (ATP5MK) LDTP10432 12.55  LDD1904 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 18.77  LDD1904 
ATPase family AAA domain-containing protein 3B (ATAD3B) LDTP07154 13.27  LDD1904 
ATPase GET3 (GET3) LDTP00836 13.27  LDD1904 
Atypical kinase COQ8A, mitochondrial (COQ8A) LDTP09285 53.08  LDD1904 
Atypical kinase COQ8B, mitochondrial (COQ8B) LDTP10201 14.62  LDD1904 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 12.21  LDD1904 
Beta-galactosidase (GLB1) LDTP02837 23.10  LDD1904 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 12.82  LDD1904 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 33.13  LDD1904 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 32.67  LDD1904 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 12.91  LDD1904 
Cartilage-associated protein (CRTAP) LDTP01300 12.55  LDD1904 
Catechol O-methyltransferase (COMT) LDTP03145 29.86  LDD1904 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 52.35  LDD1904 
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) LDTP00416 13.83  LDD1904 
Ceramide glucosyltransferase (UGCG) LDTP06617 16.11  LDD1904 
Ceramide synthase 2 (CERS2) LDTP10329 19.70  LDD1904 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 20.82  LDD1904 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 23.75  LDD1904 
Cytochrome b-c1 complex subunit 7 (UQCRB) LDTP02757 12.13  LDD1904 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 84.45  LDD1904 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 65.34  LDD1904 
Cytochrome b5 type B (CYB5B) LDTP00697 76.64  LDD1904 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 16.34  LDD1904 
Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L) LDTP14427 13.64  LDD1904 
Cytochrome c1, heme protein, mitochondrial (CYC1) LDTP02283 14.72  LDD1904 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 19.03  LDD1904 
Dehydrogenase/reductase SDR family member 7 (DHRS7) LDTP13959 16.22  LDD1904 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 23.92  LDD1904 
Delta(14)-sterol reductase TM7SF2 (TM7SF2) LDTP01389 13.64  LDD1904 
Delta(24)-sterol reductase (DHCR24) LDTP06375 30.06  LDD1904 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 25.81  LDD1904 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 18.25  LDD1904 
Distal membrane-arm assembly complex protein 2 (DMAC2) LDTP12708 11.88  LDD1904 
DNA-directed RNA polymerase, mitochondrial (POLRMT) LDTP00267 12.73  LDD1904 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 13.93  LDD1904 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 31.78  LDD1904 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 73.52  LDD1904 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 12.38  LDD1904 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 17.03  LDD1904 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 16.34  LDD1904 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 16.56  LDD1904 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 15.03  LDD1904 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 23.75  LDD1904 
GPI-anchor transamidase (PIGK) LDTP09835 12.82  LDD1904 
GTP-binding protein SAR1a (SAR1A) LDTP12470 16.45  LDD1904 
Heme A synthase COX15 (COX15) LDTP07931 32.22  LDD1904 
Heme oxygenase 1 (HMOX1) LDTP02359 24.42  LDD1904 
Heme oxygenase 2 (HMOX2) LDTP03540 40.22  LDD1904 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 27.10  LDD1904 
Hexokinase-2 (HK2) LDTP04531 13.27  LDD1904 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 17.88  LDD1904 
Holocytochrome c-type synthase (HCCS) LDTP04581 56.49  LDD1904 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 46.85  LDD1904 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 11.31  LDD1904 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 28.84  LDD1904 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 13.93  LDD1904 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 57.68  LDD1904 
Lysophospholipase D GDPD1 (GDPD1) LDTP09000 11.96  LDD1904 
Lysophospholipid acyltransferase 5 (LPCAT3) LDTP07504 11.71  LDD1904 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 14.12  LDD1904 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 38.85  LDD1904 
Lysosomal acid phosphatase (ACP2) LDTP02539 17.39  LDD1904 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 16.22  LDD1904 
Lysosomal protective protein (CTSA) LDTP02505 13.45  LDD1904 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 20.11  LDD1904 
Methionine aminopeptidase 1 (METAP1) LDTP04565 15.35  LDD1904 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 44.94  LDD1904 
Minor histocompatibility antigen H13 (HM13) LDTP09396 61.82  LDD1904 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 21.86  LDD1904 
Mitochondrial import inner membrane translocase subunit TIM50 (TIMM50) LDTP06810 11.47  LDD1904 
Mitochondrial intermediate peptidase (MIPEP) LDTP10981 26.54  LDD1904 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 15.35  LDD1904 
Mitofusin-1 (MFN1) LDTP08530 14.83  LDD1904 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 14.72  LDD1904 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 16.56  LDD1904 
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) LDTP08598 12.55  LDD1904 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 93.05  LDD1904 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 36.25  LDD1904 
NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) LDTP01219 24.76  LDD1904 
NADH dehydrogenase 1 beta subcomplex subunit 10 (NDUFB10) LDTP01743 13.27  LDD1904 
NADH dehydrogenase 1 beta subcomplex subunit 11, mitochondrial (NDUFB11) LDTP12752 13.27  LDD1904 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 70.52  LDD1904 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 24.93  LDD1904 
NADH dehydrogenase 1 subunit C2 (NDUFC2) LDTP01560 12.21  LDD1904 
NADH dehydrogenase iron-sulfur protein 2, mitochondrial (NDUFS2) LDTP01168 13.83  LDD1904 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 23.10  LDD1904 
NADPH--cytochrome P450 reductase (POR) LDTP02848 16.00  LDD1904 
Neurolysin, mitochondrial (NLN) LDTP11494 13.45  LDD1904 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 34.54  LDD1904 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 35.26  LDD1904 
Palmitoyltransferase ZDHHC13 (ZDHHC13) LDTP08455 17.63  LDD1904 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 11.71  LDD1904 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 12.55  LDD1904 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 19.03  LDD1904 
Phosphatidate cytidylyltransferase 2 (CDS2) LDTP01649 15.24  LDD1904 
Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) LDTP12608 14.32  LDD1904 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 26.17  LDD1904 
Phosphatidylserine synthase 2 (PTDSS2) LDTP11284 16.45  LDD1904 
Plasma membrane calcium-transporting ATPase 4 (ATP2B4) LDTP03249 14.52  LDD1904 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 19.43  LDD1904 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 28.64  LDD1904 
Probable glutathione peroxidase 8 (GPX8) LDTP09495 15.78  LDD1904 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 11.55  LDD1904 
Prostaglandin E synthase 3 (PTGES3) LDTP06338 16.91  LDD1904 
Prostaglandin reductase 3 (PTGR3) LDTP15422 21.26  LDD1904 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 12.73  LDD1904 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 31.78  LDD1904 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 27.10  LDD1904 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 18.64  LDD1904 
Protein O-glucosyltransferase 1 (POGLUT1) LDTP09059 11.63  LDD1904 
Protein O-mannosyl-transferase TMTC3 (TMTC3) LDTP07868 13.64  LDD1904 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 20.25  LDD1904 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 15.56  LDD1904 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 58.49  LDD1904 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 12.47  LDD1904 
Ras-related protein Rab-10 (RAB10) LDTP04895 12.47  LDD1904 
Ras-related protein Rab-11B (RAB11B) LDTP06501 22.32  LDD1904 
Ras-related protein Rab-1A (RAB1A) LDTP05006 13.18  LDD1904 
Ras-related protein Rab-24 (RAB24) LDTP10020 21.26  LDD1904 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 23.43  LDD1904 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 13.27  LDD1904 
Retinol dehydrogenase 13 (RDH13) LDTP09061 20.39  LDD1904 
Retinol dehydrogenase 14 (RDH14) LDTP12180 15.67  LDD1904 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 14.12  LDD1904 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 15.35  LDD1904 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 23.26  LDD1904 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 41.07  LDD1904 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 78.25  LDD1904 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 25.28  LDD1904 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 13.74  LDD1904 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 17.03  LDD1904 
Sphingomyelin phosphodiesterase (SMPD1) LDTP02896 21.11  LDD1904 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 27.10  LDD1904 
Squalene monooxygenase (SQLE) LDTP06142 17.88  LDD1904 
Stearoyl-CoA desaturase (SCD) LDTP00344 13.36  LDD1904 
Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) LDTP03139 21.41  LDD1904 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 11.96  LDD1904 
Thiol S-methyltransferase TMT1B (TMT1B) LDTP15155 15.14  LDD1904 
Thioredoxin, mitochondrial (TXN2) LDTP10973 12.30  LDD1904 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 26.17  LDD1904 
Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) LDTP07227 19.56  LDD1904 
Torsin-1A (TOR1A) LDTP00399 12.13  LDD1904 
Torsin-1B (TOR1B) LDTP00400 12.04  LDD1904 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 25.81  LDD1904 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 15.14  LDD1904 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 14.72  LDD1904 
Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) LDTP06901 20.39  LDD1904 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 41.36  LDD1904 
Vesicle transport protein GOT1B (GOLT1B) LDTP13986 16.34  LDD1904 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 99.04  LDD1904 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 46.21  LDD1904 
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (PDK1) LDTP06320 13.83  LDD1904 
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial (PDK3) LDTP06322 11.47  LDD1904 
------------------------------------------------------------------------------------
⏷ Show the Full List of 170 Enzyme
148 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 19.29  LDD1904 
Acyl-CoA-binding domain-containing protein 5 (ACBD5) LDTP07152 16.45  LDD1904 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 38.85  LDD1904 
ADP/ATP translocase 2 (SLC25A5) LDTP02087 11.39  LDD1904 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 16.34  LDD1904 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 19.56  LDD1904 
ATP synthase subunit a (MT-ATP6) LDTP01804 38.59  LDD1904 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 21.26  LDD1904 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 43.41  LDD1904 
Autophagy-related protein 9A (ATG9A) LDTP08030 15.03  LDD1904 
B-cell receptor-associated protein 31 (BCAP31) LDTP04426 21.41  LDD1904 
BOS complex subunit NCLN (NCLN) LDTP10036 12.55  LDD1904 
BRI3-binding protein (BRI3BP) LDTP15648 83.29  LDD1904 
Calcium uptake protein 1, mitochondrial (MICU1) LDTP11041 12.55  LDD1904 
Calnexin (CANX) LDTP03405 17.51  LDD1904 
Chloride channel CLIC-like protein 1 (CLCC1) LDTP10804 12.21  LDD1904 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 33.36  LDD1904 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 32.45  LDD1904 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 99.73  LDD1904 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 20.82  LDD1904 
Derlin-1 (DERL1) LDTP11245 45.25  LDD1904 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 16.56  LDD1904 
Equilibrative nucleoside transporter 1 (SLC29A1) LDTP10985 11.39  LDD1904 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 28.84  LDD1904 
ER membrane protein complex subunit 4 (EMC4) LDTP06994 14.72  LDD1904 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 99.73  LDD1904 
Essential MCU regulator, mitochondrial (SMDT1) LDTP11927 81.01  LDD1904 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 19.03  LDD1904 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 33.36  LDD1904 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 18.64  LDD1904 
H(+)/Cl(-) exchange transporter 7 (CLCN7) LDTP04463 13.93  LDD1904 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 16.11  LDD1904 
Importin subunit alpha-1 (KPNA2) LDTP04501 15.78  LDD1904 
Integral membrane protein 2B (ITM2B) LDTP13833 30.27  LDD1904 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 20.97  LDD1904 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 23.59  LDD1904 
Lysosome membrane protein 2 (SCARB2) LDTP06034 30.06  LDD1904 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 30.06  LDD1904 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 25.11  LDD1904 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 20.39  LDD1904 
Magnesium transporter protein 1 (MAGT1) LDTP11732 19.70  LDD1904 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 18.38  LDD1904 
Major facilitator superfamily domain-containing protein 8 (MFSD8) LDTP09261 20.82  LDD1904 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 31.12  LDD1904 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 22.63  LDD1904 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 50.91  LDD1904 
Metaxin-1 (MTX1) LDTP05900 21.11  LDD1904 
Metaxin-2 (MTX2) LDTP01217 13.83  LDD1904 
MFS-type transporter SLC18B1 (SLC18B1) LDTP07462 15.45  LDD1904 
MICOS complex subunit MIC26 (APOO) LDTP11250 31.12  LDD1904 
MICOS complex subunit MIC60 (IMMT) LDTP06660 12.30  LDD1904 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 12.73  LDD1904 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 21.26  LDD1904 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 15.89  LDD1904 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 20.53  LDD1904 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 24.59  LDD1904 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 46.53  LDD1904 
Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) LDTP04956 30.91  LDD1904 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 30.27  LDD1904 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 52.71  LDD1904 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 49.18  LDD1904 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 33.13  LDD1904 
Mitochondrial import receptor subunit TOM40 homolog (TOMM40) LDTP01748 11.39  LDD1904 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 37.53  LDD1904 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 22.47  LDD1904 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 44.94  LDD1904 
Mitochondrial pyruvate carrier 2 (MPC2) LDTP01631 11.55  LDD1904 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 15.67  LDD1904 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 13.18  LDD1904 
Mpv17-like protein 2 (MPV17L2) LDTP14952 21.56  LDD1904 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 18.38  LDD1904 
Nucleoporin NDC1 (NDC1) LDTP11213 20.53  LDD1904 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 37.53  LDD1904 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 19.16  LDD1904 
Peroxisomal biogenesis factor 3 (PEX3) LDTP04749 14.22  LDD1904 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 99.73  LDD1904 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 24.93  LDD1904 
Peroxisomal membrane protein PEX16 (PEX16) LDTP14181 47.18  LDD1904 
Peroxisomal membrane protein PMP34 (SLC25A17) LDTP00872 11.88  LDD1904 
PRA1 family protein 2 (PRAF2) LDTP01060 22.01  LDD1904 
PRA1 family protein 3 (ARL6IP5) LDTP01352 15.45  LDD1904 
Prohibitin 1 (PHB1) LDTP03717 13.00  LDD1904 
Prosaposin (PSAP) LDTP02215 31.12  LDD1904 
Protein ARV1 (ARV1) LDTP11812 18.13  LDD1904 
Protein FAM8A1 (FAM8A1) LDTP16190 20.39  LDD1904 
Protein GPR107 (GPR107) LDTP07236 19.97  LDD1904 
Protein GPR108 (GPR108) LDTP12383 33.59  LDD1904 
Protein RER1 (RER1) LDTP00590 19.70  LDD1904 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 28.64  LDD1904 
Protein tweety homolog 3 (TTYH3) LDTP11615 42.52  LDD1904 
Protein wntless homolog (WLS) LDTP07156 46.21  LDD1904 
Proton-coupled amino acid transporter 1 (SLC36A1) LDTP08016 17.75  LDD1904 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 16.91  LDD1904 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 65.80  LDD1904 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 27.47  LDD1904 
Rhomboid domain-containing protein 2 (RHBDD2) LDTP07467 19.97  LDD1904 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 19.97  LDD1904 
Secretory carrier-associated membrane protein 1 (SCAMP1) LDTP00546 12.30  LDD1904 
Secretory carrier-associated membrane protein 3 (SCAMP3) LDTP00451 12.21  LDD1904 
Secretory carrier-associated membrane protein 4 (SCAMP4) LDTP09987 11.47  LDD1904 
Sideroflexin-1 (SFXN1) LDTP12090 12.55  LDD1904 
Sideroflexin-2 (SFXN2) LDTP10621 12.91  LDD1904 
Sideroflexin-4 (SFXN4) LDTP07531 26.91  LDD1904 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 11.63  LDD1904 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 20.25  LDD1904 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 28.25  LDD1904 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 42.22  LDD1904 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 37.01  LDD1904 
Solute carrier family 35 member F1 (SLC35F1) LDTP15000 19.03  LDD1904 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 15.35  LDD1904 
Solute carrier family 41 member 3 (SLC41A3) LDTP10370 16.22  LDD1904 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 21.71  LDD1904 
Sorting nexin-4 (SNX4) LDTP01531 15.35  LDD1904 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 21.71  LDD1904 
Store-operated calcium entry-associated regulatory factor (SARAF) LDTP10148 15.35  LDD1904 
SUN domain-containing protein 1 (SUN1) LDTP01454 20.97  LDD1904 
Surfeit locus protein 4 (SURF4) LDTP00592 44.63  LDD1904 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 27.10  LDD1904 
Synaptophysin (SYP) LDTP02266 24.08  LDD1904 
Syntaxin-5 (STX5) LDTP05780 19.43  LDD1904 
Tetraspanin-3 (TSPAN3) LDTP16813 99.73  LDD1904 
Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 16.00  LDD1904 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 48.84  LDD1904 
Translocation protein SEC63 homolog (SEC63) LDTP13243 12.13  LDD1904 
Translocator protein (TSPO) LDTP03546 14.42  LDD1904 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 99.73  LDD1904 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 14.42  LDD1904 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 35.75  LDD1904 
Transmembrane emp24 domain-containing protein 10 (TMED10) LDTP04293 15.03  LDD1904 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 16.34  LDD1904 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 14.42  LDD1904 
Transmembrane protein 126A (TMEM126A) LDTP15948 45.89  LDD1904 
Transmembrane protein 160 (TMEM160) LDTP20002 43.11  LDD1904 
Transmembrane protein 199 (TMEM199) LDTP08881 32.67  LDD1904 
Transmembrane protein 201 (TMEM201) LDTP07058 16.56  LDD1904 
Transmembrane protein 205 (TMEM205) LDTP07667 22.16  LDD1904 
Transmembrane protein 230 (TMEM230) LDTP10065 39.12  LDD1904 
Transmembrane protein 33 (TMEM33) LDTP04787 36.50  LDD1904 
Transmembrane protein 87A (TMEM87A) LDTP15481 64.00  LDD1904 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 41.36  LDD1904 
Vacuole membrane protein 1 (VMP1) LDTP10343 11.96  LDD1904 
Vang-like protein 1 (VANGL1) LDTP09288 19.16  LDD1904 
Vezatin (VEZT) LDTP12191 22.47  LDD1904 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 51.27  LDD1904 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 60.13  LDD1904 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 30.06  LDD1904 
Voltage-gated monoatomic cation channel TMEM109 (TMEM109) LDTP11281 37.27  LDD1904 
Wolframin (WFS1) LDTP01380 19.70  LDD1904 
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⏷ Show the Full List of 148 Transporter and channel
2 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 12.64  LDD1904 
Paraspeckle component 1 (PSPC1) LDTP09694 11.88  LDD1904 
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3 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 20.53  LDD1904 
Junctional adhesion molecule C (JAM3) LDTP11355 14.12  LDD1904 
Leukocyte surface antigen CD47 (CD47) LDTP05572 24.42  LDD1904 
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124 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Amyloid beta precursor like protein 2 (APLP2) LDTP05491 14.83  LDD1904 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 15.67  LDD1904 
Apolipoprotein L2 (APOL2) LDTP11076 99.73  LDD1904 
Armadillo repeat-containing protein 1 (ARMC1) LDTP12692 11.63  LDD1904 
ATP synthase subunit ATP5MJ, mitochondrial (ATP5MJ) LDTP14716 22.94  LDD1904 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 20.97  LDD1904 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 23.75  LDD1904 
Calmodulin-3 (CALM3) LDTP02443 13.74  LDD1904 
Calumenin (CALU) LDTP00887 11.79  LDD1904 
cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) LDTP02511 12.73  LDD1904 
Centrin-2 (CETN2) LDTP03926 32.22  LDD1904 
Centrosomal protein 43 (CEP43) LDTP01652 25.28  LDD1904 
Clustered mitochondria protein homolog (CLUH) LDTP14486 18.90  LDD1904 
Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) LDTP12379 12.91  LDD1904 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 12.55  LDD1904 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 85.04  LDD1904 
DDRGK domain-containing protein 1 (DDRGK1) LDTP10403 13.09  LDD1904 
DNA replication complex GINS protein PSF2 (GINS2) LDTP13802 14.72  LDD1904 
DnaJ homolog subfamily C member 11 (DNAJC11) LDTP12677 22.32  LDD1904 
Dynactin subunit 2 (DCTN2) LDTP05922 11.47  LDD1904 
Emerin (EMD) LDTP04356 13.93  LDD1904 
Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) LDTP10775 14.42  LDD1904 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 99.73  LDD1904 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 99.73  LDD1904 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 34.54  LDD1904 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 12.04  LDD1904 
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (ECSIT) LDTP11065 14.72  LDD1904 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 27.10  LDD1904 
Ganglioside GM2 activator (GM2A) LDTP02927 14.12  LDD1904 
General transcription factor IIF subunit 1 (GTF2F1) LDTP03729 13.55  LDD1904 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 22.16  LDD1904 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 33.82  LDD1904 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 36.50  LDD1904 
Golgi phosphoprotein 3-like (GOLPH3L) LDTP11910 13.74  LDD1904 
Golgin subfamily B member 1 (GOLGB1) LDTP06210 14.52  LDD1904 
Guanine nucleotide-binding protein G(i) subunit alpha-1 (GNAI1) LDTP05041 15.35  LDD1904 
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 (GNG5) LDTP05054 15.67  LDD1904 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 13.18  LDD1904 
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) LDTP05530 18.25  LDD1904 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 15.67  LDD1904 
Integral membrane protein GPR180 (GPR180) LDTP19625 11.31  LDD1904 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 99.73  LDD1904 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 28.84  LDD1904 
Large proline-rich protein BAG6 (BAG6) LDTP04094 13.09  LDD1904 
Large ribosomal subunit protein mL55 (MRPL55) LDTP15269 15.89  LDD1904 
Large ribosomal subunit protein mL64 (GADD45GIP1) LDTP09297 11.47  LDD1904 
m-AAA protease-interacting protein 1, mitochondrial (MAIP1) LDTP09644 12.55  LDD1904 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 22.16  LDD1904 
Matrix-remodeling-associated protein 7 (MXRA7) LDTP17003 18.00  LDD1904 
Membralin (TMEM259) LDTP14939 51.27  LDD1904 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 33.82  LDD1904 
MICOS complex subunit MIC27 (APOOL) LDTP07718 18.64  LDD1904 
Microtubule-associated protein RP/EB family member 2 (MAPRE2) LDTP06413 16.11  LDD1904 
Mitochondrial antiviral-signaling protein (MAVS) LDTP08058 15.56  LDD1904 
Mitochondrial fission 1 protein (FIS1) LDTP13982 13.18  LDD1904 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 14.62  LDD1904 
Mitochondrial import inner membrane translocase subunit TIM14 (DNAJC19) LDTP10207 11.55  LDD1904 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 12.47  LDD1904 
Mitochondrial import receptor subunit TOM20 homolog (TOMM20) LDTP06373 19.56  LDD1904 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 49.52  LDD1904 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 80.45  LDD1904 
Mitochondrial import receptor subunit TOM6 homolog (TOMM6) LDTP10113 12.47  LDD1904 
Mitochondrial import receptor subunit TOM7 homolog (TOMM7) LDTP12982 25.63  LDD1904 
Mitochondrial potassium channel (CCDC51) LDTP10275 14.42  LDD1904 
Negative elongation factor C/D (NELFCD) LDTP08594 11.79  LDD1904 
Neudesin (NENF) LDTP13630 12.30  LDD1904 
Nicastrin (NCSTN) LDTP09787 15.89  LDD1904 
NLR family member X1 (NLRX1) LDTP08248 22.16  LDD1904 
Nucleobindin-2 (NUCB2) LDTP05160 60.97  LDD1904 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 14.52  LDD1904 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 13.55  LDD1904 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 25.11  LDD1904 
Optic atrophy 3 protein (OPA3) LDTP16006 50.91  LDD1904 
Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) LDTP11906 24.59  LDD1904 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 22.01  LDD1904 
Polyadenylate-binding protein-interacting protein 2 (PAIP2) LDTP11044 13.45  LDD1904 
Pre-mRNA 3'-end-processing factor FIP1 (FIP1L1) LDTP07655 13.64  LDD1904 
Prohibitin-2 (PHB2) LDTP10924 22.47  LDD1904 
Proteasome maturation protein (POMP) LDTP13800 14.22  LDD1904 
Protein ecdysoneless homolog (ECD) LDTP01711 12.82  LDD1904 
Protein FAM114A2 (FAM114A2) LDTP16080 32.90  LDD1904 
Protein FAM162A (FAM162A) LDTP10056 99.73  LDD1904 
Protein FAM177A1 (FAM177A1) LDTP15398 18.25  LDD1904 
Protein jagunal homolog 1 (JAGN1) LDTP08904 29.45  LDD1904 
Protein LYRIC (MTDH) LDTP08224 90.51  LDD1904 
Protein SET (SET) LDTP05277 42.52  LDD1904 
Protein transport protein Sec16A (SEC16A) LDTP00512 14.93  LDD1904 
Protein YIF1A (YIF1A) LDTP01494 69.55  LDD1904 
Rab9 effector protein with kelch motifs (RABEPK) LDTP08130 16.68  LDD1904 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 14.32  LDD1904 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 16.11  LDD1904 
Reticulocalbin-2 (RCN2) LDTP06097 16.91  LDD1904 
Reticulon-2 (RTN2) LDTP01167 16.91  LDD1904 
Reticulon-3 (RTN3) LDTP01522 99.73  LDD1904 
Reticulon-4 (RTN4) LDTP12412 66.72  LDD1904 
Reticulophagy regulator 3 (RETREG3) LDTP08300 14.03  LDD1904 
Ribonucleoprotein PTB-binding 1 (RAVER1) LDTP15356 11.88  LDD1904 
RUS family member 1 (RUSF1) LDTP10357 17.51  LDD1904 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 12.13  LDD1904 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 17.88  LDD1904 
Small integral membrane protein 12 (SMIM12) LDTP19859 18.38  LDD1904 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 30.48  LDD1904 
Striatin (STRN) LDTP00875 13.27  LDD1904 
Superkiller complex protein 3 (SKIC3) LDTP07574 11.39  LDD1904 
Surfeit locus protein 1 (SURF1) LDTP06404 11.79  LDD1904 
Synaptogyrin-2 (SYNGR2) LDTP00859 58.49  LDD1904 
Syntaxin-12 (STX12) LDTP08389 12.04  LDD1904 
Syntaxin-18 (STX18) LDTP13086 41.64  LDD1904 
Syntaxin-7 (STX7) LDTP00632 13.74  LDD1904 
Syntaxin-8 (STX8) LDTP13664 12.73  LDD1904 
Tetraspanin-6 (TSPAN6) LDTP14458 74.03  LDD1904 
Thioredoxin domain-containing protein 15 (TXNDC15) LDTP10442 22.78  LDD1904 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 47.18  LDD1904 
TraB domain-containing protein (TRABD) LDTP19963 32.45  LDD1904 
Trafficking protein particle complex subunit 4 (TRAPPC4) LDTP13837 13.36  LDD1904 
Transducin beta-like protein 2 (TBL2) LDTP16285 12.82  LDD1904 
Translocon-associated protein subunit delta (SSR4) LDTP04425 19.43  LDD1904 
Transmembrane emp24 domain-containing protein 5 (TMED5) LDTP13967 12.91  LDD1904 
Transmembrane protein 209 (TMEM209) LDTP18272 32.90  LDD1904 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 12.47  LDD1904 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 19.16  LDD1904 
UPF0729 protein C18orf32 (C18orf32) LDTP15599 13.00  LDD1904 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 19.70  LDD1904 
Wings apart-like protein homolog (WAPL) LDTP08094 14.83  LDD1904 
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⏷ Show the Full List of 124 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1904 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587