Details of the Target

General Information of Target

Target ID LDTP19005
Target Name SLC35A4 upstream open reading frame protein (SLC35A4)
Gene Name SLC35A4
Synonyms
SLC35A4 upstream open reading frame protein
3D Structure
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2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MGRIPGGCSSKAFIGRAQWLTPVIPALWEAKGLTLLSRLECSDVIMDHCSPQLTGLRMKG
FLAQTPPLEFPVHQYQPGDHVLIKSWKRESLNQLRRTSSGTLDE
Target Bioclass
Other
Subcellular location
Membrane
Uniprot ID
L0R6Q1
Ensemble ID
ENST00000623481.3
HGNC ID
HGNC:20753

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
NAIA_4
 Probe Info  		N.A.  LDD2226  [1]
TFBX
 Probe Info  		N.A.  LDD0027  [2]
STPyne
 Probe Info  		N.A.  LDD0009  [3]
PAL-AfBPP Probe
Click To Hide/Show 40 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C022
 Probe Info  		6.68  LDD1728  [4]
C055
 Probe Info  		14.03  LDD1752  [4]
C056
 Probe Info  		29.65  LDD1753  [4]
C091
 Probe Info  		13.36  LDD1782  [4]
C092
 Probe Info  		22.63  LDD1783  [4]
C094
 Probe Info  		34.78  LDD1785  [4]
C106
 Probe Info  		22.16  LDD1793  [4]
C112
 Probe Info  		25.11  LDD1799  [4]
C134
 Probe Info  		25.81  LDD1816  [4]
C143
 Probe Info  		15.35  LDD1825  [4]
C153
 Probe Info  		20.82  LDD1834  [4]
C161
 Probe Info  		10.13  LDD1841  [4]
C178
 Probe Info  		15.14  LDD1857  [4]
C201
 Probe Info  		44.94  LDD1877  [4]
C206
 Probe Info  		15.24  LDD1881  [4]
C210
 Probe Info  		48.50  LDD1884  [4]
C218
 Probe Info  		13.18  LDD1892  [4]
C220
 Probe Info  		15.24  LDD1894  [4]
C228
 Probe Info  		19.16  LDD1901  [4]
C231
 Probe Info  		17.88  LDD1904  [4]
C235
 Probe Info  		19.29  LDD1908  [4]
C238
 Probe Info  		12.73  LDD1911  [4]
C246
 Probe Info  		13.36  LDD1919  [4]
C264
 Probe Info  		17.03  LDD1935  [4]
C278
 Probe Info  		67.65  LDD1948  [4]
C285
 Probe Info  		29.04  LDD1955  [4]
C287
 Probe Info  		11.96  LDD1957  [4]
C289
 Probe Info  		81.01  LDD1959  [4]
C293
 Probe Info  		20.11  LDD1963  [4]
C296
 Probe Info  		19.43  LDD1966  [4]
C314
 Probe Info  		15.14  LDD1981  [4]
C339
 Probe Info  		4.92  LDD2002  [4]
C343
 Probe Info  		15.35  LDD2005  [4]
C349
 Probe Info  		10.78  LDD2010  [4]
C350
 Probe Info  		41.07  LDD2011  [4]
C362
 Probe Info  		77.17  LDD2023  [4]
C388
 Probe Info  		61.39  LDD2047  [4]
C390
 Probe Info  		23.26  LDD2049  [4]
C403
 Probe Info  		14.42  LDD2061  [4]
C407
 Probe Info  		15.78  LDD2064  [4]

References

1 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
2 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
3 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
4 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587