Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C362  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 164 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11127  ADP-dependent glucokinase (ADPGK) 99.7
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 99.7
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 99.7
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 99.7
 LDTP12873  CDGSH iron-sulfur domain-containing protein 1 (CISD1) 99.7
 LDTP10329  Ceramide synthase 2 (CERS2) 99.7
 LDTP00697  Cytochrome b5 type B (CYB5B) 99.7
 LDTP13352  GTP:AMP phosphotransferase AK3, mitochondrial (AK3) 99.7
 LDTP02359  Heme oxygenase 1 (HMOX1) 99.7
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 99.7
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 99.7
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 99.7
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 99.7
 LDTP01335  Protein SCO1 homolog, mitochondrial (SCO1) 99.7
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 99.7
 LDTP01982  NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) 95.7
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 95.7
 LDTP01803  Adenosine deaminase (ADA) 92.4
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 91.8
 LDTP01502  NADH dehydrogenase 1 beta subcomplex subunit 6 (NDUFB6) 91.1
 LDTP09799  DCN1-like protein 4 (DCUN1D4) 88.6
 LDTP03540  Heme oxygenase 2 (HMOX2) 82.7
 LDTP08728  Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) 74.5
 LDTP03145  Catechol O-methyltransferase (COMT) 72.0
 LDTP13620  Lysosomal thioesterase PPT2 (PPT2) 72.0
 LDTP17305  Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) 70.5
 LDTP09251  Atlastin-2 (ATL2) 69.6
 LDTP01773  Cytochrome c oxidase subunit 2 (MT-CO2) 69.6
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 68.6
 LDTP05905  Acid ceramidase (ASAH1) 68.1
 LDTP09396  Minor histocompatibility antigen H13 (HM13) 66.7
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 64.0
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 63.1
 LDTP05758  S-methyl-5'-thioadenosine phosphorylase (MTAP) 62.2
 LDTP11733  Ras-related protein Rab-1B (RAB1B) 61.8
 LDTP15480  Prenylcysteine oxidase-like (PCYOX1L) 61.4
 LDTP02486  Lysosomal alpha-glucosidase (GAA) 61.0
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 60.5
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 57.7
 LDTP03139  Succinate dehydrogenase iron-sulfur subunit, mitochondrial (SDHB) 56.1
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 55.7
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 55.3
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 54.6
 LDTP03189  Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) 54.2
 LDTP07931  Heme A synthase COX15 (COX15) 52.3
 LDTP12197  Ethanolamine kinase 1 (ETNK1) 52.0
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 50.2
 LDTP04634  Alpha-N-acetylglucosaminidase (NAGLU) 49.5
 LDTP06657  2-hydroxyacylsphingosine 1-beta-galactosyltransferase (UGT8) 49.2
 LDTP13986  Vesicle transport protein GOT1B (GOLT1B) 49.2
 LDTP04565  Methionine aminopeptidase 1 (METAP1) 48.5
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1) 48.2
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 47.2
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 47.2
 LDTP06901  Very-long-chain 3-oxoacyl-CoA reductase (HSD17B12) 46.9
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 45.6
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1) 45.6
 LDTP09285  Atypical kinase COQ8A, mitochondrial (COQ8A) 45.3
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 44.3
 LDTP06988  2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (COQ5) 43.7
 LDTP12763  Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) 42.8
 LDTP00400  Torsin-1B (TOR1B) 42.8
 LDTP10188  FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) 42.5
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 42.2
 LDTP11199  DCN1-like protein 5 (DCUN1D5) 41.9
 LDTP06617  Ceramide glucosyltransferase (UGCG) 41.6
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 41.6
 LDTP04581  Holocytochrome c-type synthase (HCCS) 41.1
 LDTP03854  Vitamin K-dependent gamma-carboxylase (GGCX) 40.8
 LDTP12253  Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) 40.5
 LDTP01649  Phosphatidate cytidylyltransferase 2 (CDS2) 40.5
 LDTP07756  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (HACD2) 40.2
 LDTP02150  ATP synthase subunit beta, mitochondrial (ATP5F1B) 39.9
 LDTP08598  NAD-dependent protein deacetylase sirtuin-2 (SIRT2) 39.9
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 39.7
 LDTP03198  Ferrochelatase, mitochondrial (FECH) 39.7
 LDTP00831  NADH dehydrogenase 1 beta subcomplex subunit 5, mitochondrial (NDUFB5) 39.7
 LDTP12040  Prostaglandin E synthase 2 (PTGES2) 39.7
 LDTP01065  E3 ubiquitin-protein ligase TRIM13 (TRIM13) 39.4
 LDTP10322  Abasic site processing protein HMCES (HMCES) 38.6
 LDTP00836  ATPase GET3 (GET3) 38.1
 LDTP05632  Mitochondrial-processing peptidase subunit alpha (PMPCA) 38.1
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 38.1
 LDTP00344  Stearoyl-CoA desaturase (SCD) 38.1
 LDTP12720  Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) 37.3
 LDTP13367  Glutathione hydrolase 7 (GGT7) 37.0
 LDTP04895  Ras-related protein Rab-10 (RAB10) 37.0
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 37.0
 LDTP04008  Endothelin-converting enzyme 1 (ECE1) 35.8
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 35.8
 LDTP12586  Phenylalanine--tRNA ligase beta subunit (FARSB) 35.5
 LDTP05476  3-ketodihydrosphingosine reductase (KDSR) 35.3
 LDTP00950  Dynamin-like 120 kDa protein, mitochondrial (OPA1) 35.3
 LDTP19851  Isochorismatase domain-containing protein 1 (ISOC1) 35.3
 LDTP00877  Protein SCO2 homolog, mitochondrial (SCO2) 35.3
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 34.8
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 34.5
 LDTP13220  Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) 34.1
 LDTP09620  Soluble calcium-activated nucleotidase 1 (CANT1) 34.1
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 33.8
 LDTP13959  Dehydrogenase/reductase SDR family member 7 (DHRS7) 33.1
 LDTP02539  Lysosomal acid phosphatase (ACP2) 32.9
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 32.4
 LDTP02713  Macrophage migration inhibitory factor (MIF) 32.4
 LDTP11247  Oxidoreductase HTATIP2 (HTATIP2) 32.0
 LDTP05622  Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (MGAT2) 31.8
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 31.8
 LDTP17699  GTP-binding protein 8 (GTPBP8) 31.6
 LDTP13486  Long-chain-fatty-acid--CoA ligase 6 (ACSL6) 31.6
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) 31.6
 LDTP06142  Squalene monooxygenase (SQLE) 31.6
 LDTP03779  Copper-transporting ATPase 2 (ATP7B) 31.3
 LDTP06905  Acylglycerol kinase, mitochondrial (AGK) 31.1
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 31.1
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 30.9
 LDTP10471  Protein disulfide-isomerase TMX3 (TMX3) 30.9
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 30.7
 LDTP01219  NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) 30.7
 LDTP10550  Dehydrogenase/reductase SDR family member 1 (DHRS1) 30.5
 LDTP07620  Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (PAOX) 30.5
 LDTP01300  Cartilage-associated protein (CRTAP) 30.1
 LDTP04318  Glycogen synthase kinase-3 alpha (GSK3A) 29.7
 LDTP08530  Mitofusin-1 (MFN1) 29.7
 LDTP09814  Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) 29.0
 LDTP10530  Beta-1,3-galactosyltransferase 6 (B3GALT6) 29.0
 LDTP00837  Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1) 29.0
 LDTP07227  Threonylcarbamoyladenosine tRNA methylthiotransferase (CDKAL1) 29.0
 LDTP07154  ATPase family AAA domain-containing protein 3B (ATAD3B) 28.8
 LDTP00416  CDP-diacylglycerol--inositol 3-phosphatidyltransferase (CDIPT) 28.8
 LDTP09874  Endoplasmic reticulum protein SC65 (P3H4) 28.8
 LDTP12470  GTP-binding protein SAR1a (SAR1A) 28.6
 LDTP01329  Lathosterol oxidase (SC5D) 28.4
 LDTP15484  Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) 28.2
 LDTP16007  Lipid droplet-associated hydrolase (LDAH) 28.1
 LDTP12109  Ribitol 5-phosphate transferase FKRP (FKRP) 27.9
 LDTP09053  Xyloside xylosyltransferase 1 (XXYLT1) 27.9
 LDTP15155  Thiol S-methyltransferase TMT1B (TMT1B) 27.7
 LDTP03677  Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (MAN1A1) 27.5
 LDTP01514  NADH dehydrogenase 1 beta subcomplex subunit 4 (NDUFB4) 27.5
 LDTP04892  Ras-related protein Rab-2A (RAB2A) 27.5
 LDTP03769  Sterol O-acyltransferase 1 (SOAT1) 27.5
 LDTP14276  NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) 27.3
 LDTP14218  Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) 27.3
 LDTP06986  Rab-like protein 3 (RABL3) 27.1
 LDTP09074  UDP-glucuronic acid decarboxylase 1 (UXS1) 27.1
 LDTP00597  Serine palmitoyltransferase 1 (SPTLC1) 26.9
 LDTP02896  Sphingomyelin phosphodiesterase (SMPD1) 26.7
 LDTP00415  Acyl-coenzyme A thioesterase 8 (ACOT8) 26.5
 LDTP05228  Calcium-transporting ATPase type 2C member 1 (ATP2C1) 26.5
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 26.5
 LDTP10966  Microsomal glutathione S-transferase 2 (MGST2) 26.4
 LDTP04494  NADH dehydrogenase 1 alpha subcomplex subunit 8 (NDUFA8) 26.4
 LDTP05006  Ras-related protein Rab-1A (RAB1A) 26.2
 LDTP12868  Endoplasmic reticulum aminopeptidase 1 (ERAP1) 26.0
 LDTP00032  2-hydroxyacyl-CoA lyase 2 (ILVBL) 25.8
 LDTP00186  Alkyldihydroxyacetonephosphate synthase, peroxisomal (AGPS) 25.8
 LDTP14427  Cytochrome c oxidase subunit 7A-related protein, mitochondrial (COX7A2L) 25.8
 LDTP14030  V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) 25.8
 LDTP07003  Presequence protease, mitochondrial (PITRM1) 25.6
 LDTP12415  Adenosine 5'-monophosphoramidase HINT3 (HINT3) 25.5
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 25.5
 LDTP12608  Phosphatidylinositol-3-phosphatase SAC1 (SACM1L) 25.5
 LDTP03965  Enoyl-CoA delta isomerase 1, mitochondrial (ECI1) 25.3
 LDTP12363  Lysophosphatidic acid phosphatase type 6 (ACP6) 25.3
Transporter and channel
Click to Show/Hide to Show 144 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 99.7
 LDTP01804  ATP synthase subunit a (MT-ATP6) 99.7
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 99.7
 LDTP15648  BRI3-binding protein (BRI3BP) 99.7
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 99.7
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 99.7
 LDTP11245  Derlin-1 (DERL1) 99.7
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 99.7
 LDTP01542  Golgi SNAP receptor complex member 1 (GOSR1) 99.7
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 99.7
 LDTP06275  Lysosomal-associated transmembrane protein 4A (LAPTM4A) 99.7
 LDTP10669  Melanoma inhibitory activity protein 2 (MIA2) 99.7
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 99.7
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 99.7
 LDTP04956  Mitochondrial import inner membrane translocase subunit Tim10 (TIMM10) 99.7
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 99.7
 LDTP14099  Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) 99.7
 LDTP12207  Putative divalent cation/proton antiporter TMEM165 (TMEM165) 99.7
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 99.7
 LDTP16813  Tetraspanin-3 (TSPAN3) 99.7
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 99.7
 LDTP06365  Transmembrane emp24 domain-containing protein 2 (TMED2) 99.7
 LDTP15948  Transmembrane protein 126A (TMEM126A) 99.7
 LDTP20002  Transmembrane protein 160 (TMEM160) 99.7
 LDTP10065  Transmembrane protein 230 (TMEM230) 99.7
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 99.7
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 97.7
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 97.0
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 95.0
 LDTP09333  Golgin subfamily A member 5 (GOLGA5) 91.8
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 88.0
 LDTP05900  Metaxin-1 (MTX1) 85.0
 LDTP00262  Acetyl-coenzyme A transporter 1 (SLC33A1) 84.4
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 83.9
 LDTP13320  Prenylated Rab acceptor protein 1 (RABAC1) 83.3
 LDTP00857  Syntaxin-6 (STX6) 83.3
 LDTP02215  Prosaposin (PSAP) 82.7
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 82.1
 LDTP12331  Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) 81.0
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 80.4
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 77.7
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 77.2
 LDTP10081  Leucine-rich repeat-containing protein 59 (LRRC59) 76.6
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 76.1
 LDTP08981  Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) 74.5
 LDTP03559  High affinity cationic amino acid transporter 1 (SLC7A1) 74.0
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 71.0
 LDTP14200  Mitochondrial ornithine transporter 1 (SLC25A15) 70.0
 LDTP11844  Protein spinster homolog 1 (SPNS1) 69.1
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 68.1
 LDTP07467  Rhomboid domain-containing protein 2 (RHBDD2) 67.2
 LDTP04789  Synaptojanin-2-binding protein (SYNJ2BP) 66.7
 LDTP11626  Protein YIPF3 (YIPF3) 65.8
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 65.3
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 62.2
 LDTP01060  PRA1 family protein 2 (PRAF2) 58.9
 LDTP07236  Protein GPR107 (GPR107) 58.9
 LDTP12383  Protein GPR108 (GPR108) 58.9
 LDTP07477  Transmembrane protein 214 (TMEM214) 55.7
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 55.3
 LDTP01671  STARD3 N-terminal-like protein (STARD3NL) 55.3
 LDTP04426  B-cell receptor-associated protein 31 (BCAP31) 53.8
 LDTP03905  Peroxisomal biogenesis factor 19 (PEX19) 53.8
 LDTP00872  Peroxisomal membrane protein PMP34 (SLC25A17) 52.3
 LDTP07439  Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) 52.0
 LDTP11116  45 kDa calcium-binding protein (SDF4) 49.9
 LDTP00547  Secretory carrier-associated membrane protein 2 (SCAMP2) 49.5
 LDTP08881  Transmembrane protein 199 (TMEM199) 49.5
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 49.2
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 49.2
 LDTP01309  Renin receptor (ATP6AP2) 49.2
 LDTP12979  Transmembrane protein 14C (TMEM14C) 49.2
 LDTP04787  Transmembrane protein 33 (TMEM33) 49.2
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 48.8
 LDTP12451  Integral membrane protein 2C (ITM2C) 48.2
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 48.2
 LDTP11615  Protein tweety homolog 3 (TTYH3) 46.9
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 44.6
 LDTP01601  Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) 44.0
 LDTP18459  StAR-related lipid transfer protein 7, mitochondrial (STARD7) 42.8
 LDTP01160  Peroxisomal membrane protein 11A (PEX11A) 42.5
 LDTP07531  Sideroflexin-4 (SFXN4) 42.5
 LDTP04663  Bax inhibitor 1 (TMBIM6) 41.9
 LDTP15481  Transmembrane protein 87A (TMEM87A) 41.6
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 41.4
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 40.2
 LDTP03380  Stomatin (STOM) 40.2
 LDTP07667  Transmembrane protein 205 (TMEM205) 40.2
 LDTP08030  Autophagy-related protein 9A (ATG9A) 39.9
 LDTP06633  Reticulon-1 (RTN1) 39.9
 LDTP10073  Protein RFT1 homolog (RFT1) 39.7
 LDTP10804  Chloride channel CLIC-like protein 1 (CLCC1) 38.1
 LDTP00821  Mitochondrial import inner membrane translocase subunit TIM44 (TIMM44) 37.5
 LDTP07058  Transmembrane protein 201 (TMEM201) 37.5
 LDTP06660  MICOS complex subunit MIC60 (IMMT) 37.3
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 37.3
 LDTP00541  NPC intracellular cholesterol transporter 1 (NPC1) 36.0
 LDTP04293  Transmembrane emp24 domain-containing protein 10 (TMED10) 35.5
 LDTP13953  Endophilin-B1 (SH3GLB1) 35.0
 LDTP16201  B-cell receptor-associated protein 29 (BCAP29) 34.8
 LDTP04237  Protein ERGIC-53 (LMAN1) 34.5
 LDTP14174  Sorting nexin-5 (SNX5) 34.5
 LDTP05875  Transmembrane emp24 domain-containing protein 1 (TMED1) 34.3
 LDTP14717  ATP synthase subunit e, mitochondrial (ATP5ME) 34.1
 LDTP03546  Translocator protein (TSPO) 33.6
 LDTP02608  ADP/ATP translocase 1 (SLC25A4) 33.4
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 32.7
 LDTP09789  Transmembrane 9 superfamily member 4 (TM9SF4) 32.4
 LDTP13201  Vesicle transport through interaction with t-SNAREs homolog 1B (VTI1B) 32.2
 LDTP01200  Peroxisomal membrane protein PEX14 (PEX14) 32.0
 LDTP11634  Derlin-2 (DERL2) 31.6
 LDTP11281  Voltage-gated monoatomic cation channel TMEM109 (TMEM109) 31.1
 LDTP04592  Monocarboxylate transporter 1 (SLC16A1) 30.7
 LDTP00590  Protein RER1 (RER1) 30.7
 LDTP05238  Solute carrier family 25 member 3 (SLC25A3) 30.7
 LDTP11229  Transmembrane protein 70, mitochondrial (TMEM70) 30.7
 LDTP05871  Protein OS-9 (OS9) 30.5
 LDTP12695  Trimeric intracellular cation channel type B (TMEM38B) 30.5
 LDTP13943  Thioredoxin-related transmembrane protein 2 (TMX2) 29.4
 LDTP05528  Apoptosis regulator BAX (BAX) 29.2
 LDTP16103  ATP-binding cassette sub-family F member 3 (ABCF3) 29.2
 LDTP09288  Vang-like protein 1 (VANGL1) 29.2
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 29.0
 LDTP14084  Sorting and assembly machinery component 50 homolog (SAMM50) 29.0
 LDTP08673  Calcium uptake protein 2, mitochondrial (MICU2) 28.8
 LDTP15979  Transmembrane protein 245 (TMEM245) 28.8
 LDTP10343  Vacuole membrane protein 1 (VMP1) 28.8
 LDTP01631  Mitochondrial pyruvate carrier 2 (MPC2) 28.6
 LDTP10621  Sideroflexin-2 (SFXN2) 28.4
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 28.2
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 27.7
 LDTP13599  Calcium load-activated calcium channel (TMCO1) 27.5
 LDTP10985  Equilibrative nucleoside transporter 1 (SLC29A1) 27.5
 LDTP02122  Integrin beta-1 (ITGB1) 27.5
 LDTP15838  Translocation protein SEC62 (SEC62) 27.3
 LDTP11041  Calcium uptake protein 1, mitochondrial (MICU1) 26.7
 LDTP09028  Mitoguardin 1 (MIGA1) 26.7
 LDTP04553  Tricarboxylate transport protein, mitochondrial (SLC25A1) 26.7
 LDTP16190  Protein FAM8A1 (FAM8A1) 26.5
 LDTP03405  Calnexin (CANX) 26.4
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 26.4
 LDTP00127  Nuclear envelope pore membrane protein POM 121C (POM121C) 26.2
 LDTP02087  ADP/ATP translocase 2 (SLC25A5) 25.8
 LDTP10769  Intermembrane lipid transfer protein VPS13A (VPS13A) 25.3
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 59.7
Immunoglobulin
Click to Show/Hide to Show 2 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP05572  Leukocyte surface antigen CD47 (CD47) 83.3
 LDTP03772  Basigin (BSG) 36.8
Other
Click to Show/Hide to Show 148 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP11076  Apolipoprotein L2 (APOL2) 99.7
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 99.7
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 99.7
 LDTP18467  LYR motif-containing protein 2 (LYRM2) 99.7
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 99.7
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 99.7
 LDTP16006  Optic atrophy 3 protein (OPA3) 99.7
 LDTP10056  Protein FAM162A (FAM162A) 99.7
 LDTP01522  Reticulon-3 (RTN3) 99.7
 LDTP12412  Reticulon-4 (RTN4) 99.7
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 99.7
 LDTP00986  Syntaxin-10 (STX10) 99.7
 LDTP13086  Syntaxin-18 (STX18) 99.7
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 99.7
 LDTP19963  TraB domain-containing protein (TRABD) 99.7
 LDTP05160  Nucleobindin-2 (NUCB2) 98.4
 LDTP15067  Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) 95.7
 LDTP07891  Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) 88.6
 LDTP08594  Negative elongation factor C/D (NELFCD) 88.6
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 82.7
 LDTP10786  Formin-binding protein 1 (FNBP1) 82.7
 LDTP15112  Mitochondrial fission regulator 2 (MTFR2) 80.4
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 79.9
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 77.2
 LDTP19005  SLC35A4 upstream open reading frame protein (SLC35A4) 77.2
 LDTP06291  ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL6IP1) 76.6
 LDTP01932  Prelamin-A/C (LMNA) 72.0
 LDTP12379  Complex I assembly factor TIMMDC1, mitochondrial (TIMMDC1) 68.6
 LDTP02927  Ganglioside GM2 activator (GM2A) 67.2
 LDTP08224  Protein LYRIC (MTDH) 67.2
 LDTP19780  Keratinocyte-associated transmembrane protein 2 (KCT2) 66.3
 LDTP08606  Nurim (NRM) 66.3
 LDTP16080  Protein FAM114A2 (FAM114A2) 65.8
 LDTP02297  Vimentin (VIM) 63.6
 LDTP13802  DNA replication complex GINS protein PSF2 (GINS2) 63.1
 LDTP10442  Thioredoxin domain-containing protein 15 (TXNDC15) 62.7
 LDTP11911  Golgi phosphoprotein 3 (GOLPH3) 61.8
 LDTP01494  Protein YIF1A (YIF1A) 61.4
 LDTP11326  FUN14 domain-containing protein 2 (FUNDC2) 61.0
 LDTP10403  DDRGK domain-containing protein 1 (DDRGK1) 59.3
 LDTP05960  Trophoblast glycoprotein (TPBG) 58.5
 LDTP05715  Vesicle transport protein SEC20 (BNIP1) 58.1
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 56.1
 LDTP14126  Mitochondrial import inner membrane translocase subunit Tim9 (TIMM9) 56.1
 LDTP04703  Tumor protein D52 (TPD52) 55.7
 LDTP02124  Keratin, type I cytoskeletal 18 (KRT18) 55.3
 LDTP08904  Protein jagunal homolog 1 (JAGN1) 54.6
 LDTP03926  Centrin-2 (CETN2) 53.8
 LDTP11981  Receptor expression-enhancing protein 4 (REEP4) 53.1
 LDTP19021  EF-hand calcium-binding domain-containing protein 14 (EFCAB14) 52.7
 LDTP10046  Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) 52.7
 LDTP10924  Prohibitin-2 (PHB2) 51.3
 LDTP04356  Emerin (EMD) 49.9
 LDTP09787  Nicastrin (NCSTN) 48.5
 LDTP14259  Testis-expressed protein 264 (TEX264) 47.8
 LDTP13922  Tudor and KH domain-containing protein (TDRKH) 46.5
 LDTP16116  BSD domain-containing protein 1 (BSDC1) 45.9
 LDTP00397  Golgi SNAP receptor complex member 2 (GOSR2) 45.9
 LDTP05530  Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) 45.6
 LDTP00850  ER lumen protein-retaining receptor 3 (KDELR3) 44.6
 LDTP13967  Transmembrane emp24 domain-containing protein 5 (TMED5) 44.0
 LDTP10889  Perilipin-2 (PLIN2) 43.7
 LDTP00859  Synaptogyrin-2 (SYNGR2) 41.6
 LDTP05257  Receptor expression-enhancing protein 5 (REEP5) 41.1
 LDTP00759  Tumor protein D54 (TPD52L2) 39.7
 LDTP04557  Arfaptin-2 (ARFIP2) 39.4
 LDTP07718  MICOS complex subunit MIC27 (APOOL) 39.4
 LDTP02841  Intron Large complex component GCFC2 (GCFC2) 38.3
 LDTP02180  Neurofilament light polypeptide (NEFL) 38.3
 LDTP00199  HCLS1-associated protein X-1 (HAX1) 37.5
 LDTP11140  Peroxiredoxin-like 2A (PRXL2A) 37.3
 LDTP00632  Syntaxin-7 (STX7) 37.3
 LDTP10184  HAUS augmin-like complex subunit 1 (HAUS1) 37.0
 LDTP17003  Matrix-remodeling-associated protein 7 (MXRA7) 36.8
 LDTP15778  Protein PRRC1 (PRRC1) 36.8
 LDTP04207  Heat shock 70 kDa protein 13 (HSPA13) 36.5
 LDTP14792  Small ribosomal subunit protein uS9m (MRPS9) 36.5
 LDTP09324  Ganglioside-induced differentiation-associated protein 1 (GDAP1) 36.3
 LDTP12729  Required for meiotic nuclear division protein 1 homolog (RMND1) 36.3
 LDTP08793  Armadillo repeat-containing protein 10 (ARMC10) 36.0
 LDTP10775  Endoplasmic reticulum-Golgi intermediate compartment protein 2 (ERGIC2) 35.5
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 35.3
 LDTP00779  Trans-Golgi network integral membrane protein 2 (TGOLN2) 35.3
 LDTP02181  Neurofilament medium polypeptide (NEFM) 35.0
 LDTP04425  Translocon-associated protein subunit delta (SSR4) 35.0
 LDTP19625  Integral membrane protein GPR180 (GPR180) 34.8
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 34.8
 LDTP10927  COP9 signalosome complex subunit 8 (COPS8) 34.3
 LDTP07368  Tetratricopeptide repeat protein 19, mitochondrial (TTC19) 33.1
 LDTP11044  Polyadenylate-binding protein-interacting protein 2 (PAIP2) 32.7
 LDTP07681  Bombesin receptor-activated protein C6orf89 (C6orf89) 31.8
 LDTP10255  Protein Hook homolog 2 (HOOK2) 31.8
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 30.7
 LDTP00573  Prefoldin subunit 6 (PFDN6) 30.7
 LDTP02887  Transmembrane protein 11, mitochondrial (TMEM11) 30.7
 LDTP07632  Type-1 angiotensin II receptor-associated protein (AGTRAP) 29.9
 LDTP01359  Dynactin subunit 3 (DCTN3) 29.7
 LDTP08300  Reticulophagy regulator 3 (RETREG3) 29.7
 LDTP06515  Coiled-coil domain-containing protein 6 (CCDC6) 29.4
 LDTP06527  Alpha-internexin (INA) 29.2
 LDTP07042  Protein Smaug homolog 2 (SAMD4B) 28.8
 LDTP03967  Lamina-associated polypeptide 2, isoform alpha (TMPO) 28.4
 LDTP08154  Large ribosomal subunit protein uL10m (MRPL10) 28.4
 LDTP15269  Large ribosomal subunit protein mL55 (MRPL55) 28.1
 LDTP13626  Ubiquilin-1 (UBQLN1) 28.1
 LDTP10389  Transmembrane protein 19 (TMEM19) 27.7
 LDTP02443  Calmodulin-3 (CALM3) 27.5
 LDTP12468  Diablo IAP-binding mitochondrial protein (DIABLO) 27.5
 LDTP01067  Endothelial differentiation-related factor 1 (EDF1) 27.5
 LDTP03065  Lamin-B1 (LMNB1) 27.5
 LDTP11774  Oxysterol-binding protein-related protein 2 (OSBPL2) 27.5
 LDTP11978  HAUS augmin-like complex subunit 4 (HAUS4) 27.3
 LDTP05375  Nucleobindin-1 (NUCB1) 27.3
 LDTP09215  Torsin-1A-interacting protein 2 (TOR1AIP2) 27.3
 LDTP09806  UBX domain-containing protein 4 (UBXN4) 27.3
 LDTP16577  DENN domain-containing protein 11 (DENND11) 27.1
 LDTP06097  Reticulocalbin-2 (RCN2) 27.1
 LDTP02351  Tropomyosin alpha-1 chain (TPM1) 27.1
 LDTP05868  Protein unc-119 homolog A (UNC119) 26.9
 LDTP06948  Protein YIF1B (YIF1B) 26.9
 LDTP06659  Tumor protein D53 (TPD52L1) 26.9
 LDTP03303  Adenomatous polyposis coli protein (APC) 26.7
 LDTP20361  Coiled-coil domain-containing protein 127 (CCDC127) 26.7
 LDTP04871  Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) 26.7
 LDTP16285  Transducin beta-like protein 2 (TBL2) 26.7
 LDTP02165  Tropomyosin alpha-3 chain (TPM3) 26.7
 LDTP18575  C2 domain-containing protein 2 (C2CD2) 26.5
 LDTP13478  Ergosterol biosynthetic protein 28 homolog (ERG28) 26.5
 LDTP06210  Golgin subfamily B member 1 (GOLGB1) 26.5
 LDTP12591  Kinesin light chain 4 (KLC4) 26.5
 LDTP04094  Large proline-rich protein BAG6 (BAG6) 26.5
 LDTP08389  Syntaxin-12 (STX12) 26.5
 LDTP05400  Lamin-B2 (LMNB2) 26.4
 LDTP15398  Protein FAM177A1 (FAM177A1) 26.4
 LDTP11167  Protein YIPF4 (YIPF4) 26.4
 LDTP01466  HAUS augmin-like complex subunit 5 (HAUS5) 26.2
 LDTP04382  Kinetochore-associated protein 1 (KNTC1) 26.2
 LDTP09719  Progesterone-induced-blocking factor 1 (PIBF1) 26.2
 LDTP01661  Synaptosomal-associated protein 29 (SNAP29) 26.2
 LDTP01177  Hyaluronan mediated motility receptor (HMMR) 25.8
 LDTP04652  Eukaryotic translation initiation factor 5 (EIF5) 25.6
 LDTP09410  Protein bicaudal D homolog 2 (BICD2) 25.6
 LDTP09080  Reticulophagy regulator 2 (RETREG2) 25.6
 LDTP09069  Kinetochore protein Spc24 (SPC24) 25.3
 LDTP15863  Large ribosomal subunit protein mL45 (MRPL45) 25.3
 LDTP15885  Leucine-rich repeat-containing protein 1 (LRRC1) 25.3
 LDTP00913  Mitochondrial import inner membrane translocase subunit Tim8 A (TIMM8A) 25.3
 LDTP06373  Mitochondrial import receptor subunit TOM20 homolog (TOMM20) 25.3

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587