Details of the Target

General Information of Target

Target ID LDTP10550
Target Name Dehydrogenase/reductase SDR family member 1 (DHRS1)
Gene Name DHRS1
Gene ID 115817
Synonyms
SDR19C1; Dehydrogenase/reductase SDR family member 1; EC 1.1.1.-; Short chain dehydrogenase/reductase family 19C member 1; Protein SDR19C1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAHVSSETQDVSPKDELTASEASTRSPLCEHTFPGDSDLRSMIEEHAFQVLSQGSLLESP
SYTVCVSEPDKDDDFLSLNFPRKLWKIVESDQFKSISWDENGTCIVINEELFKKEILETK
APYRIFQTDAIKSFVRQLNLYGFSKIQQNFQRSAFLATFLSEEKESSVLSKLKFYYNPNF
KRGYPQLLVRVKRRIGVKNASPISTLFNEDFNKKHFRAGANMENHNSALAAEASEESLFS
ASKNLNMPLTRESSVRQIIANSSVPIRSGFPPPSPSTSVGPSEQIATDQHAILNQLTTIH
MHSHSTYMQARGHIVNFITTTTSQYHIISPLQNGYFGLTVEPSAVPTRYPLVSVNEAPYR
NMLPAGNPWLQMPTIADRSAAPHSRLALQPSPLDKYHPNYN
Target Bioclass
Enzyme
Family
Short-chain dehydrogenases/reductases (SDR) family
Subcellular location
Endoplasmic reticulum
Function
NADPH-dependent oxidoreductase which catalyzes the reduction of steroids (estrone, androstene-3,17-dione and cortisone) as well as prostaglandin E1, isatin and xenobiotics in vitro. May have a role in steroid and/or xenobiotic metabolism.
Uniprot ID
Q96LJ7
Ensemble ID
ENST00000288111.12
HGNC ID
HGNC:16445

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 14 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
CY4
 Probe Info  		100.00  LDD0244  [1]
TG42
 Probe Info  		6.31  LDD0043  [2]
BTD
 Probe Info  		C177(1.16)  LDD2117  [3]
AHL-Pu-1
 Probe Info  		C177(2.28)  LDD0170  [4]
DBIA
 Probe Info  		C256(1.01)  LDD0078  [5]
W1
 Probe Info  		C256(1.07)  LDD0237  [6]
IA-alkyne
 Probe Info  		C177(0.00); C235(0.00); C28(0.00); C130(0.00)  LDD0162  [7]
Lodoacetamide azide
 Probe Info  		N.A.  LDD0037  [8]
IPM
 Probe Info  		N.A.  LDD0025  [9]
JW-RF-010
 Probe Info  		C256(0.00); C63(0.00); C235(0.00)  LDD0026  [9]
WYneN
 Probe Info  		N.A.  LDD0021  [10]
TFBX
 Probe Info  		C256(0.00); C28(0.00)  LDD0148  [9]
Acrolein
 Probe Info  		C177(0.00); C28(0.00); H40(0.00); C63(0.00)  LDD0217  [11]
NAIA_5
 Probe Info  		C235(0.00); C130(0.00); C188(0.00); C10(0.00)  LDD2223  [12]
PAL-AfBPP Probe
Click To Hide/Show 77 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C004
 Probe Info  		5.98  LDD1714  [13]
C017
 Probe Info  		6.82  LDD1725  [13]
C040
 Probe Info  		22.01  LDD1740  [13]
C041
 Probe Info  		6.41  LDD1741  [13]
C049
 Probe Info  		5.70  LDD1747  [13]
C055
 Probe Info  		17.88  LDD1752  [13]
C056
 Probe Info  		36.50  LDD1753  [13]
C063
 Probe Info  		12.55  LDD1760  [13]
C070
 Probe Info  		10.70  LDD1766  [13]
C072
 Probe Info  		7.46  LDD1768  [13]
C087
 Probe Info  		14.62  LDD1779  [13]
C106
 Probe Info  		29.65  LDD1793  [13]
C107
 Probe Info  		7.16  LDD1794  [13]
C112
 Probe Info  		19.03  LDD1799  [13]
C130
 Probe Info  		7.26  LDD1812  [13]
C143
 Probe Info  		47.18  LDD1825  [13]
C145
 Probe Info  		9.25  LDD1827  [13]
C147
 Probe Info  		7.16  LDD1829  [13]
C153
 Probe Info  		15.03  LDD1834  [13]
C183
 Probe Info  		5.03  LDD1861  [13]
C185
 Probe Info  		6.23  LDD1863  [13]
C201
 Probe Info  		34.06  LDD1877  [13]
C206
 Probe Info  		15.45  LDD1881  [13]
C210
 Probe Info  		52.35  LDD1884  [13]
C212
 Probe Info  		5.62  LDD1886  [13]
C218
 Probe Info  		13.36  LDD1892  [13]
C219
 Probe Info  		7.06  LDD1893  [13]
C220
 Probe Info  		23.26  LDD1894  [13]
C222
 Probe Info  		6.87  LDD1896  [13]
C225
 Probe Info  		5.28  LDD1898  [13]
C226
 Probe Info  		9.00  LDD1899  [13]
C228
 Probe Info  		23.26  LDD1901  [13]
C232
 Probe Info  		34.06  LDD1905  [13]
C234
 Probe Info  		11.79  LDD1907  [13]
C235
 Probe Info  		17.75  LDD1908  [13]
C243
 Probe Info  		18.77  LDD1916  [13]
C244
 Probe Info  		25.28  LDD1917  [13]
C246
 Probe Info  		23.43  LDD1919  [13]
C249
 Probe Info  		20.39  LDD1922  [13]
C251
 Probe Info  		52.71  LDD1924  [13]
C252
 Probe Info  		25.28  LDD1925  [13]
C255
 Probe Info  		7.21  LDD1928  [13]
C264
 Probe Info  		25.63  LDD1935  [13]
C265
 Probe Info  		23.10  LDD1936  [13]
C273
 Probe Info  		6.28  LDD1943  [13]
C277
 Probe Info  		7.73  LDD1947  [13]
C278
 Probe Info  		75.06  LDD1948  [13]
C282
 Probe Info  		22.78  LDD1952  [13]
C284
 Probe Info  		36.76  LDD1954  [13]
C285
 Probe Info  		23.92  LDD1955  [13]
C289
 Probe Info  		34.06  LDD1959  [13]
C296
 Probe Info  		19.97  LDD1966  [13]
C299
 Probe Info  		21.26  LDD1968  [13]
C303
 Probe Info  		5.06  LDD1972  [13]
C304
 Probe Info  		6.02  LDD1973  [13]
C305
 Probe Info  		25.81  LDD1974  [13]
C346
 Probe Info  		12.64  LDD2007  [13]
C348
 Probe Info  		14.83  LDD2009  [13]
C349
 Probe Info  		9.99  LDD2010  [13]
C350
 Probe Info  		36.50  LDD2011  [13]
C362
 Probe Info  		30.48  LDD2023  [13]
C363
 Probe Info  		15.78  LDD2024  [13]
C378
 Probe Info  		6.54  LDD2037  [13]
C383
 Probe Info  		11.88  LDD2042  [13]
C384
 Probe Info  		5.13  LDD2043  [13]
C386
 Probe Info  		9.65  LDD2045  [13]
C388
 Probe Info  		36.50  LDD2047  [13]
C397
 Probe Info  		9.58  LDD2056  [13]
C399
 Probe Info  		8.63  LDD2058  [13]
C403
 Probe Info  		35.51  LDD2061  [13]
C419
 Probe Info  		9.19  LDD2074  [13]
C420
 Probe Info  		11.39  LDD2075  [13]
C423
 Probe Info  		8.57  LDD2078  [13]
VE-P
 Probe Info  		N.A.  LDD0396  [14]
A-DA
 Probe Info  		7.68  LDD0143  [15]
AEA-DA
 Probe Info  		20.00  LDD0146  [15]
OEA-DA
 Probe Info  		20.00  LDD0046  [16]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C177(1.16)  LDD2117  [3]
 LDCM0025  4SU-RNA DM93 C177(2.28)  LDD0170  [4]
 LDCM0214  AC1 HCT 116 C256(0.87); C177(1.33)  LDD0531  [5]
 LDCM0215  AC10 HCT 116 C58(0.89); C63(0.89)  LDD0532  [5]
 LDCM0216  AC100 HCT 116 C58(0.67); C63(0.67)  LDD0533  [5]
 LDCM0217  AC101 HCT 116 C58(0.74); C63(0.74)  LDD0534  [5]
 LDCM0218  AC102 HCT 116 C58(0.73); C63(0.73)  LDD0535  [5]
 LDCM0219  AC103 HCT 116 C58(0.53); C63(0.53)  LDD0536  [5]
 LDCM0220  AC104 HCT 116 C58(0.64); C63(0.64)  LDD0537  [5]
 LDCM0221  AC105 HCT 116 C58(0.58); C63(0.58)  LDD0538  [5]
 LDCM0222  AC106 HCT 116 C58(0.63); C63(0.63)  LDD0539  [5]
 LDCM0223  AC107 HCT 116 C58(0.63); C63(0.75)  LDD0540  [5]
 LDCM0224  AC108 HCT 116 C58(0.69); C63(0.71)  LDD0541  [5]
 LDCM0225  AC109 HCT 116 C58(0.62); C63(0.57)  LDD0542  [5]
 LDCM0226  AC11 HCT 116 C58(1.01); C63(1.01)  LDD0543  [5]
 LDCM0227  AC110 HCT 116 C58(0.64); C63(0.59)  LDD0544  [5]
 LDCM0228  AC111 HCT 116 C58(0.61); C63(0.59)  LDD0545  [5]
 LDCM0229  AC112 HCT 116 C58(0.67); C63(0.73)  LDD0546  [5]
 LDCM0230  AC113 HCT 116 C256(1.10); C58(1.61); C63(1.61); C28(0.78)  LDD0547  [5]
 LDCM0231  AC114 HCT 116 C256(1.02); C58(1.03); C63(1.18); C28(0.87)  LDD0548  [5]
 LDCM0232  AC115 HCT 116 C256(1.13); C58(0.81); C63(0.93); C28(0.77)  LDD0549  [5]
 LDCM0233  AC116 HCT 116 C256(1.08); C58(0.87); C63(1.82); C28(0.88)  LDD0550  [5]
 LDCM0234  AC117 HCT 116 C256(0.97); C58(0.80); C63(1.14); C28(0.91)  LDD0551  [5]
 LDCM0235  AC118 HCT 116 C256(0.91); C58(1.08); C63(1.27); C28(1.09)  LDD0552  [5]
 LDCM0236  AC119 HCT 116 C256(1.42); C58(1.04); C63(1.04); C28(0.91)  LDD0553  [5]
 LDCM0237  AC12 HCT 116 C58(0.87); C63(0.87)  LDD0554  [5]
 LDCM0238  AC120 HCT 116 C256(1.17); C58(0.95); C63(2.38); C28(0.77)  LDD0555  [5]
 LDCM0239  AC121 HCT 116 C256(0.83); C58(1.08); C63(2.12); C28(0.99)  LDD0556  [5]
 LDCM0240  AC122 HCT 116 C256(1.11); C58(1.19); C63(1.24); C28(0.84)  LDD0557  [5]
 LDCM0241  AC123 HCT 116 C256(0.95); C58(0.64); C63(0.70); C28(0.92)  LDD0558  [5]
 LDCM0242  AC124 HCT 116 C256(0.97); C58(0.85); C63(1.28); C28(1.04)  LDD0559  [5]
 LDCM0243  AC125 HCT 116 C256(1.03); C58(1.05); C63(1.62); C28(1.00)  LDD0560  [5]
 LDCM0244  AC126 HCT 116 C256(1.11); C58(1.35); C63(1.13); C28(1.06)  LDD0561  [5]
 LDCM0245  AC127 HCT 116 C256(1.05); C58(1.01); C63(1.20); C28(0.97)  LDD0562  [5]
 LDCM0246  AC128 HCT 116 C256(1.63)  LDD0563  [5]
 LDCM0247  AC129 HCT 116 C256(1.05)  LDD0564  [5]
 LDCM0249  AC130 HCT 116 C256(1.44)  LDD0566  [5]
 LDCM0250  AC131 HCT 116 C256(20.00)  LDD0567  [5]
 LDCM0251  AC132 HCT 116 C256(1.13)  LDD0568  [5]
 LDCM0252  AC133 HCT 116 C256(1.19)  LDD0569  [5]
 LDCM0253  AC134 HCT 116 C256(1.24)  LDD0570  [5]
 LDCM0254  AC135 HCT 116 C256(1.89)  LDD0571  [5]
 LDCM0255  AC136 HCT 116 C256(2.76)  LDD0572  [5]
 LDCM0256  AC137 HCT 116 C256(1.10)  LDD0573  [5]
 LDCM0257  AC138 HCT 116 C256(1.79)  LDD0574  [5]
 LDCM0258  AC139 HCT 116 C256(1.52)  LDD0575  [5]
 LDCM0259  AC14 HCT 116 C58(0.67); C63(0.67)  LDD0576  [5]
 LDCM0260  AC140 HCT 116 C256(1.62)  LDD0577  [5]
 LDCM0261  AC141 HCT 116 C256(1.27)  LDD0578  [5]
 LDCM0262  AC142 HCT 116 C256(0.86)  LDD0579  [5]
 LDCM0263  AC143 HCT 116 C256(1.28); C177(1.12)  LDD0580  [5]
 LDCM0264  AC144 HCT 116 C256(1.00); C177(1.43)  LDD0581  [5]
 LDCM0265  AC145 HCT 116 C256(1.05); C177(1.48)  LDD0582  [5]
 LDCM0266  AC146 HCT 116 C177(1.09); C256(1.15)  LDD0583  [5]
 LDCM0267  AC147 HCT 116 C256(0.92); C177(1.33)  LDD0584  [5]
 LDCM0268  AC148 HCT 116 C177(1.17); C256(1.32)  LDD0585  [5]
 LDCM0269  AC149 HCT 116 C256(1.27); C177(1.31)  LDD0586  [5]
 LDCM0270  AC15 HCT 116 C58(0.78); C63(0.78)  LDD0587  [5]
 LDCM0271  AC150 HCT 116 C256(0.99); C177(1.32)  LDD0588  [5]
 LDCM0272  AC151 HCT 116 C256(1.02); C177(1.32)  LDD0589  [5]
 LDCM0273  AC152 HCT 116 C177(1.01); C256(1.02)  LDD0590  [5]
 LDCM0274  AC153 HCT 116 C256(1.54); C177(1.77)  LDD0591  [5]
 LDCM0621  AC154 HCT 116 C256(1.03); C177(1.30)  LDD2158  [5]
 LDCM0622  AC155 HCT 116 C256(1.04); C177(1.13)  LDD2159  [5]
 LDCM0623  AC156 HCT 116 C256(1.02); C177(1.28)  LDD2160  [5]
 LDCM0624  AC157 HCT 116 C256(1.10); C177(1.28)  LDD2161  [5]
 LDCM0276  AC17 HCT 116 C58(0.67); C63(0.67); C28(0.98); C256(1.19)  LDD0593  [5]
 LDCM0277  AC18 HCT 116 C58(0.41); C63(0.41); C28(1.09); C256(1.34)  LDD0594  [5]
 LDCM0278  AC19 HCT 116 C58(0.87); C63(0.87); C28(1.17); C256(1.24)  LDD0595  [5]
 LDCM0279  AC2 HCT 116 C256(0.74); C177(1.19)  LDD0596  [5]
 LDCM0280  AC20 HCT 116 C58(0.64); C63(0.64); C28(0.91); C256(1.30)  LDD0597  [5]
 LDCM0281  AC21 HCT 116 C58(0.56); C63(0.56); C28(0.96); C256(1.41)  LDD0598  [5]
 LDCM0282  AC22 HCT 116 C28(0.93); C58(1.06); C63(1.06); C256(1.15)  LDD0599  [5]
 LDCM0283  AC23 HCT 116 C58(0.81); C63(0.81); C28(1.14); C256(1.28)  LDD0600  [5]
 LDCM0284  AC24 HCT 116 C28(1.02); C58(1.03); C63(1.03); C256(1.31)  LDD0601  [5]
 LDCM0285  AC25 HCT 116 C177(1.05); C58(1.57); C63(1.57); C256(1.77)  LDD0602  [5]
 LDCM0286  AC26 HCT 116 C58(0.51); C63(0.51); C256(0.98); C177(1.02)  LDD0603  [5]
 LDCM0287  AC27 HCT 116 C58(0.52); C63(0.52); C256(1.08); C177(1.21)  LDD0604  [5]
 LDCM0288  AC28 HCT 116 C58(0.51); C63(0.51); C256(1.10); C177(1.11)  LDD0605  [5]
 LDCM0289  AC29 HCT 116 C58(0.50); C63(0.50); C177(1.17); C256(1.25)  LDD0606  [5]
 LDCM0290  AC3 HCT 116 C256(0.80); C177(1.79)  LDD0607  [5]
 LDCM0291  AC30 HCT 116 C58(0.51); C63(0.51); C177(1.15); C256(1.28)  LDD0608  [5]
 LDCM0292  AC31 HCT 116 C58(0.38); C63(0.38); C177(1.11); C256(1.96)  LDD0609  [5]
 LDCM0293  AC32 HCT 116 C58(0.36); C63(0.36); C177(1.13); C256(1.20)  LDD0610  [5]
 LDCM0294  AC33 HCT 116 C58(0.58); C63(0.58); C177(1.01); C256(1.24)  LDD0611  [5]
 LDCM0295  AC34 HCT 116 C58(0.39); C63(0.39); C177(0.97); C256(1.17)  LDD0612  [5]
 LDCM0296  AC35 HCT 116 C28(0.84); C256(1.07); C58(1.23); C63(1.23)  LDD0613  [5]
 LDCM0297  AC36 HCT 116 C28(1.04); C256(1.11); C58(1.40); C63(1.40)  LDD0614  [5]
 LDCM0298  AC37 HCT 116 C256(1.12); C58(1.13); C63(1.13); C28(1.18)  LDD0615  [5]
 LDCM0299  AC38 HCT 116 C28(1.01); C256(1.22); C58(1.34); C63(1.34)  LDD0616  [5]
 LDCM0300  AC39 HCT 116 C28(0.96); C58(1.07); C63(1.07); C256(1.27)  LDD0617  [5]
 LDCM0301  AC4 HCT 116 C256(0.80); C177(1.65)  LDD0618  [5]
 LDCM0302  AC40 HCT 116 C58(0.78); C63(0.78); C28(0.98); C256(1.21)  LDD0619  [5]
 LDCM0303  AC41 HCT 116 C58(1.12); C63(1.12); C256(1.14); C28(1.18)  LDD0620  [5]
 LDCM0304  AC42 HCT 116 C28(0.96); C58(1.12); C63(1.12); C256(1.12)  LDD0621  [5]
 LDCM0305  AC43 HCT 116 C58(0.93); C63(0.93); C28(0.94); C256(1.34)  LDD0622  [5]
 LDCM0306  AC44 HCT 116 C58(0.97); C63(0.97); C28(0.98); C256(1.05)  LDD0623  [5]
 LDCM0307  AC45 HCT 116 C58(0.78); C63(0.78); C28(1.06); C256(1.12)  LDD0624  [5]
 LDCM0308  AC46 HCT 116 C58(0.89); C63(0.89); C177(1.12); C256(1.17)  LDD0625  [5]
 LDCM0309  AC47 HCT 116 C177(1.10); C256(1.12); C58(1.15); C63(1.15)  LDD0626  [5]
 LDCM0310  AC48 HCT 116 C58(0.43); C63(0.43); C177(1.12); C256(1.66)  LDD0627  [5]
 LDCM0311  AC49 HCT 116 C58(0.52); C63(0.52); C177(1.10); C256(1.23)  LDD0628  [5]
 LDCM0312  AC5 HCT 116 C256(0.69); C177(1.73)  LDD0629  [5]
 LDCM0313  AC50 HCT 116 C58(0.82); C63(0.82); C177(1.30); C256(1.78)  LDD0630  [5]
 LDCM0314  AC51 HCT 116 C58(0.86); C63(0.86); C177(1.07); C256(1.28)  LDD0631  [5]
 LDCM0315  AC52 HCT 116 C58(0.85); C63(0.85); C256(1.12); C177(1.14)  LDD0632  [5]
 LDCM0316  AC53 HCT 116 C58(0.53); C63(0.53); C256(0.96); C177(1.27)  LDD0633  [5]
 LDCM0317  AC54 HCT 116 C58(0.53); C63(0.53); C256(1.10); C177(1.32)  LDD0634  [5]
 LDCM0318  AC55 HCT 116 C58(0.47); C63(0.47); C256(0.98); C177(1.24)  LDD0635  [5]
 LDCM0319  AC56 HCT 116 C58(0.42); C63(0.42); C177(1.19); C256(2.06)  LDD0636  [5]
 LDCM0320  AC57 HCT 116 C58(0.21); C63(0.21); C256(0.97); C28(1.28)  LDD0637  [5]
 LDCM0321  AC58 HCT 116 C58(0.18); C63(0.18); C28(0.99); C256(1.20)  LDD0638  [5]
 LDCM0322  AC59 HCT 116 C58(0.21); C63(0.21); C28(0.85); C256(1.28)  LDD0639  [5]
 LDCM0323  AC6 HCT 116 C58(1.01); C63(1.01)  LDD0640  [5]
 LDCM0324  AC60 HCT 116 C58(0.23); C63(0.23); C28(0.92); C256(1.51)  LDD0641  [5]
 LDCM0325  AC61 HCT 116 C58(0.17); C63(0.17); C256(0.97); C28(0.98)  LDD0642  [5]
 LDCM0326  AC62 HCT 116 C58(0.26); C63(0.26); C28(0.91); C256(1.22)  LDD0643  [5]
 LDCM0327  AC63 HCT 116 C58(0.15); C63(0.15); C28(0.85); C256(1.39)  LDD0644  [5]
 LDCM0328  AC64 HCT 116 C58(0.19); C63(0.19); C28(0.92); C256(0.92)  LDD0645  [5]
 LDCM0329  AC65 HCT 116 C58(0.20); C63(0.20); C28(0.78); C256(1.10)  LDD0646  [5]
 LDCM0330  AC66 HCT 116 C58(0.23); C63(0.23); C28(1.07); C256(1.22)  LDD0647  [5]
 LDCM0331  AC67 HCT 116 C58(0.13); C63(0.13); C28(0.80); C256(1.10)  LDD0648  [5]
 LDCM0332  AC68 HCT 116 C58(0.56); C63(0.56); C256(0.83)  LDD0649  [5]
 LDCM0333  AC69 HCT 116 C58(0.45); C63(0.45); C256(0.86)  LDD0650  [5]
 LDCM0334  AC7 HCT 116 C58(1.30); C63(1.30)  LDD0651  [5]
 LDCM0335  AC70 HCT 116 C58(0.35); C63(0.35); C256(0.98)  LDD0652  [5]
 LDCM0336  AC71 HCT 116 C58(0.57); C63(0.57); C256(0.90)  LDD0653  [5]
 LDCM0337  AC72 HCT 116 C256(2.01); C58(4.00); C63(4.00)  LDD0654  [5]
 LDCM0338  AC73 HCT 116 C58(0.44); C63(0.44); C256(1.04)  LDD0655  [5]
 LDCM0339  AC74 HCT 116 C58(0.52); C63(0.52); C256(1.58)  LDD0656  [5]
 LDCM0340  AC75 HCT 116 C58(0.32); C63(0.32); C256(0.98)  LDD0657  [5]
 LDCM0341  AC76 HCT 116 C58(0.48); C63(0.48); C256(0.90)  LDD0658  [5]
 LDCM0342  AC77 HCT 116 C58(0.39); C63(0.39); C256(0.79)  LDD0659  [5]
 LDCM0343  AC78 HCT 116 C58(0.47); C63(0.47); C256(1.00)  LDD0660  [5]
 LDCM0344  AC79 HCT 116 C58(0.69); C63(0.69); C256(1.05)  LDD0661  [5]
 LDCM0345  AC8 HCT 116 C58(0.81); C63(0.81)  LDD0662  [5]
 LDCM0346  AC80 HCT 116 C58(0.54); C63(0.54); C256(0.88)  LDD0663  [5]
 LDCM0347  AC81 HCT 116 C58(0.49); C63(0.49); C256(0.82)  LDD0664  [5]
 LDCM0348  AC82 HCT 116 C58(0.37); C63(0.37); C256(0.88)  LDD0665  [5]
 LDCM0349  AC83 HCT 116 C58(0.64); C63(0.64); C28(0.87); C256(1.34)  LDD0666  [5]
 LDCM0350  AC84 HCT 116 C58(0.67); C63(0.67); C28(1.07); C256(1.30)  LDD0667  [5]
 LDCM0351  AC85 HCT 116 C58(0.62); C63(0.62); C28(0.86); C256(1.26)  LDD0668  [5]
 LDCM0352  AC86 HCT 116 C28(0.99); C256(1.35); C58(1.46); C63(1.46)  LDD0669  [5]
 LDCM0353  AC87 HCT 116 C58(0.82); C63(0.82); C28(0.95); C256(1.25)  LDD0670  [5]
 LDCM0354  AC88 HCT 116 C28(2.20); C58(2.41); C63(2.41); C256(3.11)  LDD0671  [5]
 LDCM0355  AC89 HCT 116 C58(0.74); C63(0.74); C28(1.02); C256(1.27)  LDD0672  [5]
 LDCM0357  AC90 HCT 116 C28(1.08); C256(1.34); C58(1.43); C63(1.43)  LDD0674  [5]
 LDCM0358  AC91 HCT 116 C58(0.56); C63(0.56); C28(0.89); C256(1.34)  LDD0675  [5]
 LDCM0359  AC92 HCT 116 C58(0.67); C63(0.67); C28(1.01); C256(1.18)  LDD0676  [5]
 LDCM0360  AC93 HCT 116 C28(0.88); C58(1.11); C63(1.11); C256(1.22)  LDD0677  [5]
 LDCM0361  AC94 HCT 116 C28(1.12); C256(1.21); C58(1.21); C63(1.21)  LDD0678  [5]
 LDCM0362  AC95 HCT 116 C58(0.69); C63(0.69); C28(1.05); C256(1.16)  LDD0679  [5]
 LDCM0363  AC96 HCT 116 C58(0.60); C63(0.60); C28(1.20); C256(1.47)  LDD0680  [5]
 LDCM0364  AC97 HCT 116 C28(1.06); C256(1.39); C58(1.52); C63(1.52)  LDD0681  [5]
 LDCM0365  AC98 HCT 116 C58(0.54); C63(0.54)  LDD0682  [5]
 LDCM0366  AC99 HCT 116 C58(0.66); C63(0.66)  LDD0683  [5]
 LDCM0248  AKOS034007472 HCT 116 C58(1.11); C63(1.11)  LDD0565  [5]
 LDCM0356  AKOS034007680 HCT 116 C58(0.79); C63(0.79)  LDD0673  [5]
 LDCM0275  AKOS034007705 HCT 116 C58(0.48); C63(0.48)  LDD0592  [5]
 LDCM0020  ARS-1620 HCC44 C256(1.01)  LDD0078  [5]
 LDCM0083  Avasimibe A-549 7.68  LDD0143  [15]
 LDCM0108  Chloroacetamide HeLa C28(0.00); H40(0.00); C177(0.00); C256(0.00)  LDD0222  [11]
 LDCM0632  CL-Sc Hep-G2 C10(3.08)  LDD2227  [12]
 LDCM0367  CL1 HCT 116 C28(0.97); C58(1.04); C63(1.04); C256(2.73)  LDD0684  [5]
 LDCM0368  CL10 HCT 116 C58(0.65); C63(0.65); C256(0.86); C28(0.89)  LDD0685  [5]
 LDCM0369  CL100 HCT 116 C256(0.94); C177(1.41)  LDD0686  [5]
 LDCM0370  CL101 HCT 116 C58(0.69); C63(0.69)  LDD0687  [5]
 LDCM0371  CL102 HCT 116 C58(0.84); C63(0.84)  LDD0688  [5]
 LDCM0372  CL103 HCT 116 C58(1.76); C63(1.76)  LDD0689  [5]
 LDCM0373  CL104 HCT 116 C58(0.77); C63(0.77)  LDD0690  [5]
 LDCM0374  CL105 HCT 116 C58(0.51); C63(0.51); C28(1.15); C256(1.46)  LDD0691  [5]
 LDCM0375  CL106 HCT 116 C58(0.32); C63(0.32); C28(1.29); C256(1.74)  LDD0692  [5]
 LDCM0376  CL107 HCT 116 C58(0.54); C63(0.54); C28(0.97); C256(1.38)  LDD0693  [5]
 LDCM0377  CL108 HCT 116 C58(0.33); C63(0.33); C28(1.09); C256(1.41)  LDD0694  [5]
 LDCM0378  CL109 HCT 116 C58(0.56); C63(0.56); C28(0.96); C256(1.29)  LDD0695  [5]
 LDCM0379  CL11 HCT 116 C58(0.65); C63(0.65); C28(1.02); C256(2.41)  LDD0696  [5]
 LDCM0380  CL110 HCT 116 C58(0.60); C63(0.60); C28(1.28); C256(1.42)  LDD0697  [5]
 LDCM0381  CL111 HCT 116 C58(0.77); C63(0.77); C28(0.91); C256(1.15)  LDD0698  [5]
 LDCM0382  CL112 HCT 116 C58(0.82); C63(0.82); C177(1.02); C256(1.03)  LDD0699  [5]
 LDCM0383  CL113 HCT 116 C58(0.51); C63(0.51); C177(0.93); C256(1.52)  LDD0700  [5]
 LDCM0384  CL114 HCT 116 C58(0.65); C63(0.65); C177(0.97); C256(1.27)  LDD0701  [5]
 LDCM0385  CL115 HCT 116 C58(0.51); C63(0.51); C177(1.10); C256(1.19)  LDD0702  [5]
 LDCM0386  CL116 HCT 116 C58(0.48); C63(0.48); C177(1.02); C256(1.21)  LDD0703  [5]
 LDCM0387  CL117 HCT 116 C58(0.63); C63(0.63); C28(0.95); C256(1.26)  LDD0704  [5]
 LDCM0388  CL118 HCT 116 C58(0.84); C63(0.84); C28(0.85); C256(1.08)  LDD0705  [5]
 LDCM0389  CL119 HCT 116 C58(0.96); C63(0.96); C28(1.01); C256(1.04)  LDD0706  [5]
 LDCM0390  CL12 HCT 116 C256(0.71); C58(0.76); C63(0.76); C28(1.00)  LDD0707  [5]
 LDCM0391  CL120 HCT 116 C28(1.07); C256(1.09); C58(1.13); C63(1.13)  LDD0708  [5]
 LDCM0392  CL121 HCT 116 C177(1.45); C256(1.50); C58(2.45); C63(2.45)  LDD0709  [5]
 LDCM0393  CL122 HCT 116 C58(0.53); C63(0.53); C177(1.17); C256(1.38)  LDD0710  [5]
 LDCM0394  CL123 HCT 116 C58(0.48); C63(0.48); C177(0.95); C256(2.26)  LDD0711  [5]
 LDCM0395  CL124 HCT 116 C58(0.52); C63(0.52); C177(1.16); C256(1.30)  LDD0712  [5]
 LDCM0396  CL125 HCT 116 C58(0.45); C63(0.45); C28(0.94); C256(1.15)  LDD0713  [5]
 LDCM0397  CL126 HCT 116 C58(0.38); C63(0.38); C28(0.77); C256(1.20)  LDD0714  [5]
 LDCM0398  CL127 HCT 116 C58(0.25); C63(0.25); C28(0.73); C256(1.13)  LDD0715  [5]
 LDCM0399  CL128 HCT 116 C58(0.25); C63(0.25); C256(0.99); C28(1.12)  LDD0716  [5]
 LDCM0400  CL13 HCT 116 C256(0.64); C58(0.66); C63(0.66); C28(1.01)  LDD0717  [5]
 LDCM0401  CL14 HCT 116 C256(0.77); C28(0.98); C58(1.00); C63(1.00)  LDD0718  [5]
 LDCM0402  CL15 HCT 116 C58(0.78); C63(0.78); C28(1.07); C256(1.26)  LDD0719  [5]
 LDCM0403  CL16 HCT 116 C58(0.74); C63(0.74); C256(1.00)  LDD0720  [5]
 LDCM0404  CL17 HCT 116 C58(0.42); C63(0.42); C28(1.12); C256(1.95)  LDD0721  [5]
 LDCM0405  CL18 HCT 116 C58(0.30); C63(0.30); C28(0.92); C256(0.96)  LDD0722  [5]
 LDCM0406  CL19 HCT 116 C58(0.39); C63(0.39); C256(1.02); C28(1.13)  LDD0723  [5]
 LDCM0407  CL2 HCT 116 C256(0.75); C28(0.92); C58(1.17); C63(1.17)  LDD0724  [5]
 LDCM0408  CL20 HCT 116 C58(0.48); C63(0.48); C28(0.79); C256(1.03)  LDD0725  [5]
 LDCM0409  CL21 HCT 116 C58(0.40); C63(0.40); C256(1.00); C28(1.05)  LDD0726  [5]
 LDCM0410  CL22 HCT 116 C58(0.36); C63(0.36); C256(0.91); C28(1.05)  LDD0727  [5]
 LDCM0411  CL23 HCT 116 C58(0.56); C63(0.56); C256(1.30); C28(1.37)  LDD0728  [5]
 LDCM0412  CL24 HCT 116 C58(0.38); C63(0.38); C256(0.96); C28(0.97)  LDD0729  [5]
 LDCM0413  CL25 HCT 116 C256(1.07); C58(0.43); C63(0.43); C28(1.07)  LDD0730  [5]
 LDCM0414  CL26 HCT 116 C256(0.95); C58(0.54); C63(0.54); C28(0.92)  LDD0731  [5]
 LDCM0415  CL27 HCT 116 C256(0.89); C58(0.49); C63(0.49); C28(1.16)  LDD0732  [5]
 LDCM0416  CL28 HCT 116 C256(0.92); C58(0.55); C63(0.55); C28(1.00)  LDD0733  [5]
 LDCM0417  CL29 HCT 116 C256(0.98); C58(0.49); C63(0.49); C28(0.89)  LDD0734  [5]
 LDCM0418  CL3 HCT 116 C256(0.67); C58(1.00); C63(1.00); C28(0.97)  LDD0735  [5]
 LDCM0419  CL30 HCT 116 C256(0.95); C58(0.58); C63(0.58); C28(1.26)  LDD0736  [5]
 LDCM0420  CL31 HCT 116 C256(1.89); C58(0.56); C63(0.56); C28(1.12)  LDD0737  [5]
 LDCM0421  CL32 HCT 116 C256(0.99); C58(0.28); C63(0.28)  LDD0738  [5]
 LDCM0422  CL33 HCT 116 C256(1.17); C58(0.31); C63(0.31)  LDD0739  [5]
 LDCM0423  CL34 HCT 116 C256(0.92); C58(0.33); C63(0.33)  LDD0740  [5]
 LDCM0424  CL35 HCT 116 C256(1.13); C58(0.39); C63(0.39)  LDD0741  [5]
 LDCM0425  CL36 HCT 116 C256(1.08); C58(0.38); C63(0.38)  LDD0742  [5]
 LDCM0426  CL37 HCT 116 C256(1.04); C58(0.35); C63(0.35)  LDD0743  [5]
 LDCM0428  CL39 HCT 116 C256(0.94); C58(0.33); C63(0.33)  LDD0745  [5]
 LDCM0429  CL4 HCT 116 C256(0.91); C58(0.86); C63(0.86); C28(1.02)  LDD0746  [5]
 LDCM0430  CL40 HCT 116 C256(2.49); C58(0.32); C63(0.32)  LDD0747  [5]
 LDCM0431  CL41 HCT 116 C256(0.92); C58(0.38); C63(0.38)  LDD0748  [5]
 LDCM0432  CL42 HCT 116 C256(0.98); C58(0.28); C63(0.28)  LDD0749  [5]
 LDCM0433  CL43 HCT 116 C256(0.99); C58(0.27); C63(0.27)  LDD0750  [5]
 LDCM0434  CL44 HCT 116 C256(0.95); C58(0.28); C63(0.28)  LDD0751  [5]
 LDCM0435  CL45 HCT 116 C256(1.16); C58(0.34); C63(0.34)  LDD0752  [5]
 LDCM0436  CL46 HCT 116 C256(1.26); C58(2.11); C63(2.11)  LDD0753  [5]
 LDCM0437  CL47 HCT 116 C256(1.24); C58(1.52); C63(1.52)  LDD0754  [5]
 LDCM0438  CL48 HCT 116 C256(1.54); C58(1.57); C63(1.57)  LDD0755  [5]
 LDCM0439  CL49 HCT 116 C256(1.20); C58(1.31); C63(1.31)  LDD0756  [5]
 LDCM0440  CL5 HCT 116 C256(0.61); C58(0.95); C63(0.95); C28(1.03)  LDD0757  [5]
 LDCM0441  CL50 HCT 116 C256(1.44); C58(1.77); C63(1.77)  LDD0758  [5]
 LDCM0442  CL51 HCT 116 C256(1.23); C58(1.47); C63(1.47)  LDD0759  [5]
 LDCM0443  CL52 HCT 116 C256(1.31); C58(1.40); C63(1.40)  LDD0760  [5]
 LDCM0444  CL53 HCT 116 C256(1.18); C58(1.88); C63(1.88)  LDD0761  [5]
 LDCM0445  CL54 HCT 116 C256(5.91); C58(1.28); C63(1.28)  LDD0762  [5]
 LDCM0446  CL55 HCT 116 C256(1.00); C58(3.50); C63(3.50)  LDD0763  [5]
 LDCM0447  CL56 HCT 116 C256(0.84); C58(1.26); C63(1.26)  LDD0764  [5]
 LDCM0448  CL57 HCT 116 C256(1.25); C58(1.28); C63(1.28)  LDD0765  [5]
 LDCM0449  CL58 HCT 116 C256(1.47); C58(1.73); C63(1.73)  LDD0766  [5]
 LDCM0450  CL59 HCT 116 C256(1.15); C58(1.76); C63(1.76)  LDD0767  [5]
 LDCM0451  CL6 HCT 116 C256(0.79); C58(0.88); C63(0.88); C28(1.18)  LDD0768  [5]
 LDCM0452  CL60 HCT 116 C256(1.21); C58(1.33); C63(1.33)  LDD0769  [5]
 LDCM0453  CL61 HCT 116 C256(1.50); C58(0.81); C63(0.81)  LDD0770  [5]
 LDCM0454  CL62 HCT 116 C256(1.25); C58(0.89); C63(0.89)  LDD0771  [5]
 LDCM0455  CL63 HCT 116 C256(1.45); C58(0.90); C63(0.90)  LDD0772  [5]
 LDCM0456  CL64 HCT 116 C256(1.43); C58(0.76); C63(0.76)  LDD0773  [5]
 LDCM0457  CL65 HCT 116 C256(1.49); C58(1.03); C63(1.03)  LDD0774  [5]
 LDCM0458  CL66 HCT 116 C256(1.41); C58(0.63); C63(0.63)  LDD0775  [5]
 LDCM0459  CL67 HCT 116 C256(1.81); C58(0.72); C63(0.72)  LDD0776  [5]
 LDCM0460  CL68 HCT 116 C256(1.11); C58(0.58); C63(0.58)  LDD0777  [5]
 LDCM0461  CL69 HCT 116 C256(1.71); C58(0.61); C63(0.61)  LDD0778  [5]
 LDCM0462  CL7 HCT 116 C256(0.76); C58(0.85); C63(0.85); C28(1.32)  LDD0779  [5]
 LDCM0463  CL70 HCT 116 C256(1.47); C58(0.62); C63(0.62)  LDD0780  [5]
 LDCM0464  CL71 HCT 116 C256(1.04); C58(0.68); C63(0.68)  LDD0781  [5]
 LDCM0465  CL72 HCT 116 C256(1.78); C58(0.83); C63(0.83)  LDD0782  [5]
 LDCM0466  CL73 HCT 116 C256(1.55); C58(0.89); C63(0.89)  LDD0783  [5]
 LDCM0467  CL74 HCT 116 C256(1.61); C58(0.72); C63(0.72)  LDD0784  [5]
 LDCM0469  CL76 HCT 116 C58(0.95); C63(0.95); C28(0.60)  LDD0786  [5]
 LDCM0470  CL77 HCT 116 C58(0.71); C63(0.71); C28(0.83)  LDD0787  [5]
 LDCM0471  CL78 HCT 116 C58(0.89); C63(0.89); C28(0.76)  LDD0788  [5]
 LDCM0472  CL79 HCT 116 C58(0.75); C63(0.75); C28(0.66)  LDD0789  [5]
 LDCM0473  CL8 HCT 116 C256(1.64); C58(0.69); C63(0.69); C28(1.01)  LDD0790  [5]
 LDCM0474  CL80 HCT 116 C58(0.77); C63(0.77); C28(0.46)  LDD0791  [5]
 LDCM0475  CL81 HCT 116 C58(0.87); C63(0.87); C28(0.78)  LDD0792  [5]
 LDCM0476  CL82 HCT 116 C58(0.75); C63(0.75); C28(0.54)  LDD0793  [5]
 LDCM0477  CL83 HCT 116 C58(0.80); C63(0.80); C28(0.57)  LDD0794  [5]
 LDCM0478  CL84 HCT 116 C58(0.64); C63(0.64); C28(0.55)  LDD0795  [5]
 LDCM0479  CL85 HCT 116 C58(0.65); C63(0.65); C28(0.76)  LDD0796  [5]
 LDCM0480  CL86 HCT 116 C58(0.79); C63(0.79); C28(1.01)  LDD0797  [5]
 LDCM0481  CL87 HCT 116 C58(0.82); C63(0.82); C28(0.71)  LDD0798  [5]
 LDCM0482  CL88 HCT 116 C58(0.71); C63(0.71); C28(0.58)  LDD0799  [5]
 LDCM0483  CL89 HCT 116 C58(0.80); C63(0.80); C28(0.46)  LDD0800  [5]
 LDCM0484  CL9 HCT 116 C256(0.81); C58(0.82); C63(0.82); C28(0.87)  LDD0801  [5]
 LDCM0485  CL90 HCT 116 C58(0.69); C63(0.69); C28(1.00)  LDD0802  [5]
 LDCM0486  CL91 HCT 116 C256(0.95); C177(1.14)  LDD0803  [5]
 LDCM0487  CL92 HCT 116 C256(1.00); C177(0.74)  LDD0804  [5]
 LDCM0488  CL93 HCT 116 C256(0.90); C177(0.84)  LDD0805  [5]
 LDCM0489  CL94 HCT 116 C256(0.82); C177(0.63)  LDD0806  [5]
 LDCM0490  CL95 HCT 116 C256(0.86); C177(0.65)  LDD0807  [5]
 LDCM0491  CL96 HCT 116 C256(0.95); C177(0.78)  LDD0808  [5]
 LDCM0492  CL97 HCT 116 C256(0.76); C177(1.03)  LDD0809  [5]
 LDCM0493  CL98 HCT 116 C256(0.85); C177(1.60)  LDD0810  [5]
 LDCM0494  CL99 HCT 116 C256(0.87); C177(1.80)  LDD0811  [5]
 LDCM0495  E2913 HEK-293T C177(0.97); C256(1.09); C28(0.97); C235(0.95)  LDD1698  [17]
 LDCM0625  F8 Ramos C28(1.38); C130(0.98); C256(0.36); C177(1.41)  LDD2187  [18]
 LDCM0082  FK866 A-549 20.00  LDD0146  [15]
 LDCM0572  Fragment10 Ramos C28(1.10); C130(0.79); C177(1.30); 0.74  LDD2189  [18]
 LDCM0573  Fragment11 Ramos C28(0.35); C130(0.06); C256(0.21); C177(11.72)  LDD2190  [18]
 LDCM0574  Fragment12 Ramos C28(1.70); C130(0.59); 1.49; C235(4.77)  LDD2191  [18]
 LDCM0575  Fragment13 Ramos C28(0.99); C130(0.46); C256(1.22); C177(0.82)  LDD2192  [18]
 LDCM0576  Fragment14 Ramos C28(1.47); C130(1.03); C256(2.03); C177(1.59)  LDD2193  [18]
 LDCM0579  Fragment20 Ramos C28(2.89); C130(2.47); C235(3.90)  LDD2194  [18]
 LDCM0580  Fragment21 Ramos C28(1.10); C130(0.36); C256(2.27); C177(1.21)  LDD2195  [18]
 LDCM0582  Fragment23 Ramos C28(0.99); C130(0.59); C256(1.58); 1.20  LDD2196  [18]
 LDCM0578  Fragment27 Ramos C28(1.00); C130(0.40); C256(0.85); C177(1.00)  LDD2197  [18]
 LDCM0586  Fragment28 Ramos C28(0.85); C130(1.20); C256(0.94); C177(0.52)  LDD2198  [18]
 LDCM0588  Fragment30 Ramos C28(1.11); C130(0.46); C256(1.98); C177(0.94)  LDD2199  [18]
 LDCM0589  Fragment31 Ramos C28(0.92); C130(0.32); C256(1.03); C177(1.07)  LDD2200  [18]
 LDCM0590  Fragment32 Ramos C28(0.69); C130(0.41); C256(14.32); C177(0.98)  LDD2201  [18]
 LDCM0468  Fragment33 HCT 116 C256(2.10); C58(0.82); C63(0.82)  LDD0785  [5]
 LDCM0596  Fragment38 Ramos C28(0.75); C130(0.24); C256(1.40); C177(1.75)  LDD2203  [18]
 LDCM0566  Fragment4 Ramos C28(1.56); C130(2.68); C256(2.43); C177(1.30)  LDD2184  [18]
 LDCM0427  Fragment51 HCT 116 C256(0.90); C58(0.30); C63(0.30)  LDD0744  [5]
 LDCM0610  Fragment52 Ramos C28(1.02); C130(0.25); C256(2.97); C177(1.71)  LDD2204  [18]
 LDCM0614  Fragment56 Ramos C28(1.26); C130(0.24); C256(1.01); C177(1.14)  LDD2205  [18]
 LDCM0569  Fragment7 Ramos C28(2.82); C130(0.97); C256(3.80); C177(1.33)  LDD2186  [18]
 LDCM0571  Fragment9 Ramos C28(4.14); C130(1.57); C235(8.78)  LDD2188  [18]
 LDCM0107  IAA HeLa N.A.  LDD0221  [11]
 LDCM0022  KB02 HCT 116 C256(2.34)  LDD0080  [5]
 LDCM0023  KB03 HCT 116 C256(3.00)  LDD0081  [5]
 LDCM0024  KB05 HCT 116 C256(1.27)  LDD0082  [5]
 LDCM0109  NEM HeLa N.A.  LDD0223  [11]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C177(1.00)  LDD2119  [3]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C28(0.31)  LDD2127  [3]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C28(3.31)  LDD2146  [3]
 LDCM0084  Ro 48-8071 A-549 12.15  LDD0145  [15]
 LDCM0136  SR-4559 HEK-293T 3.37  LDD0333  [16]
 LDCM0137  SR-4995 HEK-293T 3.14  LDD0334  [16]
 LDCM0110  W12 Hep-G2 C256(1.07)  LDD0237  [6]
 LDCM0111  W14 Hep-G2 C256(0.85)  LDD0238  [6]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 (BNIP2) . Q12982
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Endophilin-B1 (SH3GLB1) Endophilin family Q9Y371
MyoD family inhibitor (MDFI) MDFI family Q99750
Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
LIM/homeobox protein Lhx4 (LHX4) . Q969G2
Other
Click To Hide/Show 21 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Keratin, type I cuticular Ha4 (KRT34) Intermediate filament family O76011
Keratin-associated protein 1-1 (KRTAP1-1) KRTAP type 1 family Q07627
Keratin-associated protein 1-3 (KRTAP1-3) KRTAP type 1 family Q8IUG1
Keratin-associated protein 10-8 (KRTAP10-8) KRTAP type 10 family P60410
Keratin-associated protein 10-9 (KRTAP10-9) KRTAP type 10 family P60411
Keratin-associated protein 12-1 (KRTAP12-1) KRTAP type 12 family P59990
Keratin-associated protein 12-2 (KRTAP12-2) KRTAP type 12 family P59991
Keratin-associated protein 12-3 (KRTAP12-3) KRTAP type 12 family P60328
Keratin-associated protein 3-2 (KRTAP3-2) KRTAP type 3 family Q9BYR7
Keratin-associated protein 4-1 (KRTAP4-1) KRTAP type 4 family Q9BYQ7
Keratin-associated protein 4-11 (KRTAP4-11) KRTAP type 4 family Q9BYQ6
Keratin-associated protein 5-1 (KRTAP5-1) KRTAP type 5 family Q6L8H4
Keratin-associated protein 5-2 (KRTAP5-2) KRTAP type 5 family Q701N4
Keratin-associated protein 5-9 (KRTAP5-9) KRTAP type 5 family P26371
Keratin-associated protein 6-2 (KRTAP6-2) KRTAP type 6 family Q3LI66
Keratin-associated protein 9-8 (KRTAP9-8) KRTAP type 9 family Q9BYQ0
Late cornified envelope protein 2B (LCE2B) LCE family O14633
Notch homolog 2 N-terminal-like protein A (NOTCH2NLA) NOTCH family Q7Z3S9
Notch homolog 2 N-terminal-like protein C (NOTCH2NLC) NOTCH family P0DPK4
Keratin-associated protein 11-1 (KRTAP11-1) PMG family Q8IUC1
Diablo IAP-binding mitochondrial protein (DIABLO) . Q9NR28

References

1 Cyclopropenone, Cyclopropeniminium Ion, and Cyclopropenethione as Novel Electrophilic Warheads for Potential Target Discovery of Triple-Negative Breast Cancer. J Med Chem. 2023 Feb 23;66(4):2851-2864. doi: 10.1021/acs.jmedchem.2c01889. Epub 2023 Feb 10.
2 Design and synthesis of tailored human caseinolytic protease P inhibitors. Chem Commun (Camb). 2018 Aug 28;54(70):9833-9836. doi: 10.1039/c8cc05265d.
Mass spectrometry data entry: PXD010277
3 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
4 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
5 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
6 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
7 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
8 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
9 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
10 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
11 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
12 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
13 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
14 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
15 A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells. Cell. 2015 Jun 18;161(7):1668-80. doi: 10.1016/j.cell.2015.05.045.
16 Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20.
Mass spectrometry data entry: PXD007570
17 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
18 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578