Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | TG42 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | 20 uM | |||||
| Criteria | Quantification: Probe vs DMSO | |||||
| Quantitative Method |
LFQ
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Bone marrow | ||||
| Disease Model | T acute lymphoblastic leukemia [ICD-11:2A90] | |||||
| Model Name | Human T acute lymphoblastic leukemia cells (Jurkat) | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP10550 | Dehydrogenase/reductase SDR family member 1 (DHRS1) | 6.3 | ||||
| LDTP01462 | Endonuclease domain-containing 1 protein (ENDOD1) | 5.8 | ||||
| LDTP05779 | Serine/threonine-protein kinase 3 (STK3) | 4.5 | ||||
| LDTP07208 | Alpha/beta hydrolase domain-containing protein 17B (ABHD17B) | 4.4 | ||||
| LDTP01515 | NADH dehydrogenase 1 beta subcomplex subunit 8, mitochondrial (NDUFB8) | 4.4 | ||||
| LDTP07362 | Atlastin-3 (ATL3) | 4.2 | ||||
| LDTP12405 | Fructose-2,6-bisphosphatase TIGAR (TIGAR) | 4.1 | ||||
| LDTP05733 | Serine/threonine-protein kinase 4 (STK4) | 4.0 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP10065 | Transmembrane protein 230 (TMEM230) | 12.1 | ||||
| LDTP04227 | Guided entry of tail-anchored proteins factor CAMLG (CAMLG) | 6.1 | ||||
| LDTP11987 | Reticulophagy regulator 1 (RETREG1) | 5.9 | ||||
| LDTP06331 | Pericentriolar material 1 protein (PCM1) | 5.0 | ||||
| LDTP01200 | Peroxisomal membrane protein PEX14 (PEX14) | 4.6 | ||||
| LDTP09987 | Secretory carrier-associated membrane protein 4 (SCAMP4) | 4.4 | ||||
| LDTP14325 | Transmembrane protein 223 (TMEM223) | 4.2 | ||||
Transcription factor
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP00332 | Transcription factor E2F3 (E2F3) | 7.4 | ||||
| LDTP05505 | Transcription factor SOX-4 (SOX4) | 4.8 | ||||
Immunoglobulin
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP07927 | Butyrophilin subfamily 2 member A1 (BTN2A1) | 8.0 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP12412 | Reticulon-4 (RTN4) | 12.2 | ||||
| LDTP11137 | Suppressor of IKBKE 1 (SIKE1) | 11.6 | ||||
| LDTP08058 | Mitochondrial antiviral-signaling protein (MAVS) | 11.0 | ||||
| LDTP13664 | Syntaxin-8 (STX8) | 7.9 | ||||
| LDTP12544 | Serine incorporator 1 (SERINC1) | 7.4 | ||||
| LDTP01210 | Transforming acidic coiled-coil-containing protein 1 (TACC1) | 7.3 | ||||
| LDTP09121 | MAPK-interacting and spindle-stabilizing protein-like (MAPK1IP1L) | 6.9 | ||||
| LDTP19509 | Glutamate-rich protein 5 (ERICH5) | 6.9 | ||||
| LDTP15599 | UPF0729 protein C18orf32 (C18orf32) | 6.5 | ||||
| LDTP13999 | Signaling threshold-regulating transmembrane adapter 1 (SIT1) | 5.7 | ||||
| LDTP04224 | MARCKS-related protein (MARCKSL1) | 5.1 | ||||
| LDTP01600 | BAG family molecular chaperone regulator 4 (BAG4) | 4.7 | ||||
| LDTP10296 | Interleukin-17 receptor A (IL17RA) | 4.6 | ||||
| LDTP13916 | Calcium-regulated heat-stable protein 1 (CARHSP1) | 4.6 | ||||
| LDTP14228 | Transforming acidic coiled-coil-containing protein 3 (TACC3) | 4.6 | ||||
| LDTP00880 | A-kinase anchor protein 8 (AKAP8) | 4.6 | ||||
| LDTP10657 | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (ARAP1) | 4.5 | ||||
| LDTP18732 | Protein FAM234B (FAM234B) | 4.2 | ||||