Details of the Target

General Information of Target

Target ID LDTP09121
Target Name MAPK-interacting and spindle-stabilizing protein-like (MAPK1IP1L)
Gene Name MAPK1IP1L
Gene ID 93487
Synonyms
C14orf32; MAPK-interacting and spindle-stabilizing protein-like; Mitogen-activated protein kinase 1-interacting protein 1-like
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MSDEFSLADALPEHSPAKTSAVSNTKPGQPPQGWPGSNPWNNPSAPSSVPSGLPPSATPS
TVPFGPAPTGMYPSVPPTGPPPGPPAPFPPSGPSCPPPGGPYPAPTVPGPGPTGPYPTPN
MPFPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNMPYPSPGPYPAPPPP
QAPGAAPPVPWGTVPPGAWGPPAPYPAPTGSYPTPGLYPTPSNPFQVPSGPSGAPPMPGG
PHSYH
Target Bioclass
Other
Family
MISS family
Uniprot ID
Q8NDC0
Ensemble ID
ENST00000395468.9
HGNC ID
HGNC:19840

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 4 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
TG42
 Probe Info  		6.94  LDD0043  [1]
YN-1
 Probe Info  		100.00  LDD0444  [2]
AZ-9
 Probe Info  		E13(10.00)  LDD2208  [3]
m-APA
 Probe Info  		N.A.  LDD2231  [4]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Transcription factor
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Homeobox protein MSX-2 (MSX2) Msh homeobox family P35548
Other
Click To Hide/Show 19 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Keratin-associated protein 19-5 (KRTAP19-5) KRTAP type 19 family Q3LI72
Keratin-associated protein 19-7 (KRTAP19-7) KRTAP type 19 family Q3SYF9
Keratin-associated protein 6-1 (KRTAP6-1) KRTAP type 6 family Q3LI64
RNA guanine-N7 methyltransferase activating subunit (RAMAC) RAM family Q9BTL3
RNA-binding protein EWS (EWSR1) RRM TET family Q01844
Calcium-responsive transactivator (SS18L1) SS18 family O75177
Small ubiquitin-related modifier 1 (SUMO1) Ubiquitin family P63165
Small ubiquitin-related modifier 5 (SUMO1P1) Ubiquitin family G2XKQ0
Vacuolar protein sorting-associated protein 37C (VPS37C) VPS37 family A5D8V6
Centrosomal protein of 55 kDa (CEP55) . Q53EZ4
DAZ-associated protein 2 (DAZAP2) . Q15038
Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS) . O14964
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) . Q9BUJ2
Leukocyte receptor cluster member 8 (LENG8) . Q96PV6
Melanoma-associated antigen D1 (MAGED1) . Q9Y5V3
Protein TFG (TFG) . Q92734
Rho guanine nucleotide exchange factor 16 (ARHGEF16) . Q5VV41
RNA binding protein fox-1 homolog 2 (RBFOX2) . O43251
Uncharacterized protein C1orf94 (C1orf94) . Q6P1W5

References

1 Design and synthesis of tailored human caseinolytic protease P inhibitors. Chem Commun (Camb). 2018 Aug 28;54(70):9833-9836. doi: 10.1039/c8cc05265d.
Mass spectrometry data entry: PXD010277
2 Ynamide Electrophile for the Profiling of Ligandable Carboxyl Residues in Live Cells and the Development of New Covalent Inhibitors. J Med Chem. 2022 Aug 11;65(15):10408-10418. doi: 10.1021/acs.jmedchem.2c00272. Epub 2022 Jul 26.
3 2H-Azirine-Based Reagents for Chemoselective Bioconjugation at Carboxyl Residues Inside Live Cells. J Am Chem Soc. 2020 Apr 1;142(13):6051-6059. doi: 10.1021/jacs.9b12116. Epub 2020 Mar 23.
4 Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print.
Mass spectrometry data entry: PXD042377