Details of the Target

General Information of Target

Target ID LDTP19509
Target Name Glutamate-rich protein 5 (ERICH5)
Gene Name ERICH5
Gene ID 203111
Synonyms
C8orf47; Glutamate-rich protein 5
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAPQKDRKPKRSTWRFNLDLTHPVEDGIFDSGNFEQFLREKVKVNGKTGNLGNVVHIERF
KNKITVVSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDEDESES
ED
Target Bioclass
Other
Uniprot ID
Q6P6B1
Ensemble ID
ENST00000318528.8
HGNC ID
HGNC:26823

Target Site Mutations in Different Cell Lines

Cell line Mutation details Probe for labeling this protein in this cell
8505C SNV: p.Q198Ter .
HCC15 SNV: p.A215D .
HCT116 SNV: p.A11T .
HT115 SNV: p.E47Ter .
MOLT4 SNV: p.A89T .
NCIH1650 SNV: p.D51H; p.D272H .

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 1 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
TG42
 Probe Info  		6.86  LDD0043  [1]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Kelch-like ECH-associated protein 1 (KEAP1) KEAP1 family Q14145

References

1 Design and synthesis of tailored human caseinolytic protease P inhibitors. Chem Commun (Camb). 2018 Aug 28;54(70):9833-9836. doi: 10.1039/c8cc05265d.
Mass spectrometry data entry: PXD010277