Details of the Target

General Information of Target

Target ID LDTP07927
Target Name Butyrophilin subfamily 2 member A1 (BTN2A1)
Gene Name BTN2A1
Gene ID 11120
Synonyms
BT2.1; BTF1; Butyrophilin subfamily 2 member A1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MESAAALHFSRPASLLLLLLSLCALVSAQFIVVGPTDPILATVGENTTLRCHLSPEKNAE
DMEVRWFRSQFSPAVFVYKGGRERTEEQMEEYRGRTTFVSKDISRGSVALVIHNITAQEN
GTYRCYFQEGRSYDEAILHLVVAGLGSKPLISMRGHEDGGIRLECISRGWYPKPLTVWRD
PYGGVAPALKEVSMPDADGLFMVTTAVIIRDKSVRNMSCSINNTLLGQKKESVIFIPESF
MPSVSPCAVALPIIVVILMIPIAVCIYWINKLQKEKKILSGEKEFERETREIALKELEKE
RVQKEEELQVKEKLQEELRWRRTFLHAVDVVLDPDTAHPDLFLSEDRRSVRRCPFRHLGE
SVPDNPERFDSQPCVLGRESFASGKHYWEVEVENVIEWTVGVCRDSVERKGEVLLIPQNG
FWTLEMHKGQYRAVSSPDRILPLKESLCRVGVFLDYEAGDVSFYNMRDRSHIYTCPRSAF
SVPVRPFFRLGCEDSPIFICPALTGANGVTVPEEGLTLHRVGTHQSL
Target Bioclass
Immunoglobulin
Family
Immunoglobulin superfamily, BTN/MOG family
Subcellular location
Membrane
Uniprot ID
Q7KYR7
Ensemble ID
ENST00000312541.10
HGNC ID
HGNC:1136

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 6 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
TG42
 Probe Info  		8.04  LDD0043  [1]
STPyne
 Probe Info  		K277(6.29)  LDD0277  [2]
OPA-S-S-alkyne
 Probe Info  		K79(0.71); K57(2.42); K101(2.46)  LDD3494  [3]
DBIA
 Probe Info  		C374(2.34)  LDD3427  [4]
BTD
 Probe Info  		C475(0.51)  LDD2099  [5]
IA-alkyne
 Probe Info  		C492(0.00); C374(0.00); C475(0.00); C51(0.00)  LDD0165  [6]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C170
 Probe Info  		10.34  LDD1850  [7]
C310
 Probe Info  		8.11  LDD1977  [7]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C475(1.43)  LDD2152  [5]
 LDCM0214  AC1 HEK-293T C492(0.93)  LDD0812  [8]
 LDCM0215  AC10 HEK-293T C475(0.96); C374(0.99); C500(0.98); C492(1.11)  LDD1508  [9]
 LDCM0226  AC11 HEK-293T C475(0.99); C125(1.02); C500(1.02); C492(0.92)  LDD1509  [9]
 LDCM0237  AC12 HEK-293T C475(0.85); C125(0.91)  LDD1510  [9]
 LDCM0246  AC128 HEK-293T C492(1.31)  LDD0844  [8]
 LDCM0247  AC129 HEK-293T C492(1.11)  LDD0845  [8]
 LDCM0249  AC130 HEK-293T C492(1.13)  LDD0847  [8]
 LDCM0250  AC131 HEK-293T C492(1.25)  LDD0848  [8]
 LDCM0251  AC132 HEK-293T C492(1.09)  LDD0849  [8]
 LDCM0252  AC133 HEK-293T C492(1.01)  LDD0850  [8]
 LDCM0253  AC134 HEK-293T C492(1.18)  LDD0851  [8]
 LDCM0254  AC135 HEK-293T C492(1.25)  LDD0852  [8]
 LDCM0255  AC136 HEK-293T C492(1.15)  LDD0853  [8]
 LDCM0256  AC137 HEK-293T C492(1.29)  LDD0854  [8]
 LDCM0257  AC138 HEK-293T C492(1.28)  LDD0855  [8]
 LDCM0258  AC139 HEK-293T C492(1.26)  LDD0856  [8]
 LDCM0259  AC14 HEK-293T C475(0.97); C125(0.94); C500(0.77)  LDD1512  [9]
 LDCM0260  AC140 HEK-293T C492(0.98)  LDD0858  [8]
 LDCM0261  AC141 HEK-293T C492(1.12)  LDD0859  [8]
 LDCM0262  AC142 HEK-293T C492(1.11)  LDD0860  [8]
 LDCM0270  AC15 HEK-293T C475(0.95); C500(0.80); C492(0.97)  LDD1513  [9]
 LDCM0276  AC17 HEK-293T C492(0.92)  LDD0874  [8]
 LDCM0277  AC18 HEK-293T C492(0.91)  LDD0875  [8]
 LDCM0278  AC19 HEK-293T C492(0.93)  LDD0876  [8]
 LDCM0279  AC2 HEK-293T C492(0.86)  LDD0877  [8]
 LDCM0280  AC20 HEK-293T C492(0.99)  LDD0878  [8]
 LDCM0281  AC21 HEK-293T C492(0.93)  LDD0879  [8]
 LDCM0282  AC22 HEK-293T C492(0.90)  LDD0880  [8]
 LDCM0283  AC23 HEK-293T C492(0.88)  LDD0881  [8]
 LDCM0284  AC24 HEK-293T C492(0.99)  LDD0882  [8]
 LDCM0285  AC25 HEK-293T C475(1.02); C125(1.01); C500(0.76); C492(1.09)  LDD1524  [9]
 LDCM0286  AC26 HEK-293T C475(0.97); C374(1.04); C500(1.15); C492(1.40)  LDD1525  [9]
 LDCM0287  AC27 HEK-293T C475(1.02); C125(0.94); C500(0.86); C492(0.92)  LDD1526  [9]
 LDCM0288  AC28 HEK-293T C475(0.94); C125(0.80)  LDD1527  [9]
 LDCM0289  AC29 HEK-293T C475(1.04); C374(1.05); C125(0.99); C500(0.72)  LDD1528  [9]
 LDCM0290  AC3 HEK-293T C492(0.84)  LDD0888  [8]
 LDCM0291  AC30 HEK-293T C475(0.70); C125(0.97); C500(0.85)  LDD1530  [9]
 LDCM0292  AC31 HEK-293T C475(1.00); C500(0.94); C492(0.77)  LDD1531  [9]
 LDCM0293  AC32 HEK-293T C475(1.06); C125(1.02); C492(0.76)  LDD1532  [9]
 LDCM0294  AC33 HEK-293T C475(1.07); C125(1.03); C500(0.84); C492(0.84)  LDD1533  [9]
 LDCM0295  AC34 HEK-293T C475(0.95); C374(0.97); C500(1.02); C492(1.10)  LDD1534  [9]
 LDCM0296  AC35 HEK-293T C492(0.72)  LDD0894  [8]
 LDCM0297  AC36 HEK-293T C492(0.83)  LDD0895  [8]
 LDCM0298  AC37 HEK-293T C492(0.77)  LDD0896  [8]
 LDCM0299  AC38 HEK-293T C492(0.76)  LDD0897  [8]
 LDCM0300  AC39 HEK-293T C492(0.79)  LDD0898  [8]
 LDCM0301  AC4 HEK-293T C492(1.02)  LDD0899  [8]
 LDCM0302  AC40 HEK-293T C492(1.02)  LDD0900  [8]
 LDCM0303  AC41 HEK-293T C492(0.94)  LDD0901  [8]
 LDCM0304  AC42 HEK-293T C492(0.92)  LDD0902  [8]
 LDCM0305  AC43 HEK-293T C492(1.05)  LDD0903  [8]
 LDCM0306  AC44 HEK-293T C492(0.94)  LDD0904  [8]
 LDCM0307  AC45 HEK-293T C492(0.80)  LDD0905  [8]
 LDCM0308  AC46 HEK-293T C475(0.83); C125(1.03); C500(0.76)  LDD1547  [9]
 LDCM0309  AC47 HEK-293T C475(1.06); C500(0.70); C492(0.94)  LDD1548  [9]
 LDCM0310  AC48 HEK-293T C475(1.04); C125(1.15); C492(1.48)  LDD1549  [9]
 LDCM0311  AC49 HEK-293T C475(0.96); C125(1.07); C500(1.13); C492(1.04)  LDD1550  [9]
 LDCM0312  AC5 HEK-293T C492(1.07)  LDD0910  [8]
 LDCM0313  AC50 HEK-293T C475(0.87); C374(1.03); C500(1.16); C492(1.28)  LDD1552  [9]
 LDCM0314  AC51 HEK-293T C475(1.02); C125(1.06); C500(0.92); C492(1.03)  LDD1553  [9]
 LDCM0315  AC52 HEK-293T C475(0.85); C125(1.07)  LDD1554  [9]
 LDCM0316  AC53 HEK-293T C475(1.17); C374(0.98); C125(0.98); C500(0.74)  LDD1555  [9]
 LDCM0317  AC54 HEK-293T C475(0.79); C125(1.04); C500(0.91)  LDD1556  [9]
 LDCM0318  AC55 HEK-293T C475(0.95); C500(0.84); C492(0.81)  LDD1557  [9]
 LDCM0319  AC56 HEK-293T C475(0.93); C125(1.04); C492(1.09)  LDD1558  [9]
 LDCM0320  AC57 HEK-293T C492(0.87)  LDD0918  [8]
 LDCM0321  AC58 HEK-293T C492(0.87)  LDD0919  [8]
 LDCM0322  AC59 HEK-293T C492(0.81)  LDD0920  [8]
 LDCM0323  AC6 HEK-293T C475(0.92); C125(1.05); C500(0.83)  LDD1562  [9]
 LDCM0324  AC60 HEK-293T C492(0.84)  LDD0922  [8]
 LDCM0325  AC61 HEK-293T C492(0.81)  LDD0923  [8]
 LDCM0326  AC62 HEK-293T C492(0.66)  LDD0924  [8]
 LDCM0327  AC63 HEK-293T C492(0.68)  LDD0925  [8]
 LDCM0328  AC64 HEK-293T C492(0.69)  LDD0926  [8]
 LDCM0329  AC65 HEK-293T C492(0.68)  LDD0927  [8]
 LDCM0330  AC66 HEK-293T C492(0.76)  LDD0928  [8]
 LDCM0331  AC67 HEK-293T C492(0.79)  LDD0929  [8]
 LDCM0332  AC68 HEK-293T C492(1.06)  LDD0930  [8]
 LDCM0333  AC69 HEK-293T C492(0.87)  LDD0931  [8]
 LDCM0334  AC7 HEK-293T C475(1.23); C500(0.77); C492(0.85)  LDD1568  [9]
 LDCM0335  AC70 HEK-293T C492(0.81)  LDD0933  [8]
 LDCM0336  AC71 HEK-293T C492(0.72)  LDD0934  [8]
 LDCM0337  AC72 HEK-293T C492(0.87)  LDD0935  [8]
 LDCM0338  AC73 HEK-293T C492(1.04)  LDD0936  [8]
 LDCM0339  AC74 HEK-293T C492(0.95)  LDD0937  [8]
 LDCM0340  AC75 HEK-293T C492(1.05)  LDD0938  [8]
 LDCM0341  AC76 HEK-293T C492(0.89)  LDD0939  [8]
 LDCM0342  AC77 HEK-293T C492(0.82)  LDD0940  [8]
 LDCM0343  AC78 HEK-293T C492(0.94)  LDD0941  [8]
 LDCM0344  AC79 HEK-293T C492(0.91)  LDD0942  [8]
 LDCM0345  AC8 HEK-293T C475(1.04); C125(1.06); C492(0.97)  LDD1569  [9]
 LDCM0346  AC80 HEK-293T C492(1.02)  LDD0944  [8]
 LDCM0347  AC81 HEK-293T C492(0.83)  LDD0945  [8]
 LDCM0348  AC82 HEK-293T C492(0.93)  LDD0946  [8]
 LDCM0248  AKOS034007472 HEK-293T C475(1.06); C374(1.05); C125(0.87); C500(0.77)  LDD1511  [9]
 LDCM0356  AKOS034007680 HEK-293T C475(1.09); C125(1.09); C500(0.81); C492(1.03)  LDD1570  [9]
 LDCM0275  AKOS034007705 HEK-293T C475(1.06); C125(1.23); C492(1.25)  LDD1514  [9]
 LDCM0367  CL1 HEK-293T C475(1.02); C374(1.11); C500(0.85); C492(1.05)  LDD1571  [9]
 LDCM0368  CL10 HEK-293T C475(0.88); C125(1.26); C500(0.68)  LDD1572  [9]
 LDCM0369  CL100 HEK-293T C492(0.97)  LDD0967  [8]
 LDCM0370  CL101 HEK-293T C475(0.99); C374(1.03); C500(0.81); C492(0.90)  LDD1574  [9]
 LDCM0371  CL102 HEK-293T C475(1.05); C374(1.32); C500(1.03); C492(1.01)  LDD1575  [9]
 LDCM0372  CL103 HEK-293T C475(0.96)  LDD1576  [9]
 LDCM0373  CL104 HEK-293T C475(1.02); C374(1.01); C500(0.92); C492(1.00)  LDD1577  [9]
 LDCM0374  CL105 HEK-293T C492(0.96)  LDD0972  [8]
 LDCM0375  CL106 HEK-293T C492(0.90)  LDD0973  [8]
 LDCM0376  CL107 HEK-293T C492(0.93)  LDD0974  [8]
 LDCM0377  CL108 HEK-293T C492(0.85)  LDD0975  [8]
 LDCM0378  CL109 HEK-293T C492(0.88)  LDD0976  [8]
 LDCM0379  CL11 HEK-293T C475(1.14); C500(0.58); C492(0.74)  LDD1583  [9]
 LDCM0380  CL110 HEK-293T C492(0.83)  LDD0978  [8]
 LDCM0381  CL111 HEK-293T C492(0.90)  LDD0979  [8]
 LDCM0382  CL112 HEK-293T C475(1.02); C374(1.02); C500(0.77); C492(1.07)  LDD1586  [9]
 LDCM0383  CL113 HEK-293T C475(0.97); C374(1.01); C500(0.97); C492(0.97)  LDD1587  [9]
 LDCM0384  CL114 HEK-293T C475(1.10); C374(1.09); C500(0.79); C492(0.99)  LDD1588  [9]
 LDCM0385  CL115 HEK-293T C475(0.94)  LDD1589  [9]
 LDCM0386  CL116 HEK-293T C475(0.94); C374(1.07); C500(1.05); C492(0.88)  LDD1590  [9]
 LDCM0387  CL117 HEK-293T C492(0.60)  LDD0985  [8]
 LDCM0388  CL118 HEK-293T C492(0.66)  LDD0986  [8]
 LDCM0389  CL119 HEK-293T C492(0.96)  LDD0987  [8]
 LDCM0390  CL12 HEK-293T C475(1.18); C125(1.00); C492(1.46)  LDD1594  [9]
 LDCM0391  CL120 HEK-293T C492(1.00)  LDD0989  [8]
 LDCM0392  CL121 HEK-293T C475(0.99); C374(1.05); C500(1.00); C492(0.89)  LDD1596  [9]
 LDCM0393  CL122 HEK-293T C475(0.98); C374(1.20); C500(1.00); C492(1.18)  LDD1597  [9]
 LDCM0394  CL123 HEK-293T C475(1.25)  LDD1598  [9]
 LDCM0395  CL124 HEK-293T C475(0.95); C374(0.99); C500(1.17); C492(1.00)  LDD1599  [9]
 LDCM0396  CL125 HEK-293T C492(0.89)  LDD0994  [8]
 LDCM0397  CL126 HEK-293T C492(0.72)  LDD0995  [8]
 LDCM0398  CL127 HEK-293T C492(0.75)  LDD0996  [8]
 LDCM0399  CL128 HEK-293T C492(0.79)  LDD0997  [8]
 LDCM0400  CL13 HEK-293T C475(0.96); C374(1.09); C500(0.94); C492(0.81)  LDD1604  [9]
 LDCM0401  CL14 HEK-293T C475(0.94); C374(1.23); C500(0.93); C492(1.09)  LDD1605  [9]
 LDCM0402  CL15 HEK-293T C475(1.06)  LDD1606  [9]
 LDCM0403  CL16 HEK-293T C492(0.98)  LDD1001  [8]
 LDCM0404  CL17 HEK-293T C492(0.76)  LDD1002  [8]
 LDCM0405  CL18 HEK-293T C492(0.87)  LDD1003  [8]
 LDCM0406  CL19 HEK-293T C492(0.92)  LDD1004  [8]
 LDCM0407  CL2 HEK-293T C475(0.96); C374(1.07); C500(0.99); C492(0.93)  LDD1611  [9]
 LDCM0408  CL20 HEK-293T C492(0.86)  LDD1006  [8]
 LDCM0409  CL21 HEK-293T C492(0.78)  LDD1007  [8]
 LDCM0410  CL22 HEK-293T C492(0.78)  LDD1008  [8]
 LDCM0411  CL23 HEK-293T C492(0.64)  LDD1009  [8]
 LDCM0412  CL24 HEK-293T C492(0.85)  LDD1010  [8]
 LDCM0413  CL25 HEK-293T C492(0.86)  LDD1011  [8]
 LDCM0414  CL26 HEK-293T C492(0.83)  LDD1012  [8]
 LDCM0415  CL27 HEK-293T C492(0.85)  LDD1013  [8]
 LDCM0416  CL28 HEK-293T C492(0.78)  LDD1014  [8]
 LDCM0417  CL29 HEK-293T C492(0.78)  LDD1015  [8]
 LDCM0418  CL3 HEK-293T C475(1.13)  LDD1622  [9]
 LDCM0419  CL30 HEK-293T C492(0.72)  LDD1017  [8]
 LDCM0420  CL31 HEK-293T C475(1.17); C125(1.28); C500(0.81); C492(0.84)  LDD1624  [9]
 LDCM0421  CL32 HEK-293T C475(1.01); C125(0.92)  LDD1625  [9]
 LDCM0422  CL33 HEK-293T C475(1.18); C374(1.28); C125(1.14); C500(0.79)  LDD1626  [9]
 LDCM0423  CL34 HEK-293T C475(0.86); C125(1.01); C500(0.72)  LDD1627  [9]
 LDCM0424  CL35 HEK-293T C475(1.19); C500(0.71); C492(0.87)  LDD1628  [9]
 LDCM0425  CL36 HEK-293T C475(1.05); C125(1.16); C492(0.74)  LDD1629  [9]
 LDCM0426  CL37 HEK-293T C475(0.99); C374(1.04); C500(1.14); C492(1.08)  LDD1630  [9]
 LDCM0428  CL39 HEK-293T C475(1.03)  LDD1632  [9]
 LDCM0429  CL4 HEK-293T C475(0.98); C374(0.85); C500(0.80); C492(0.91)  LDD1633  [9]
 LDCM0430  CL40 HEK-293T C475(1.03); C374(1.00); C500(1.80); C492(0.83)  LDD1634  [9]
 LDCM0431  CL41 HEK-293T C475(1.03); C125(1.22); C500(0.93); C492(0.93)  LDD1635  [9]
 LDCM0432  CL42 HEK-293T C475(0.99); C374(1.01); C500(1.13); C492(1.14)  LDD1636  [9]
 LDCM0433  CL43 HEK-293T C475(1.10); C125(1.16); C500(0.96); C492(0.90)  LDD1637  [9]
 LDCM0434  CL44 HEK-293T C475(0.87); C125(0.82)  LDD1638  [9]
 LDCM0435  CL45 HEK-293T C475(1.11); C374(1.23); C125(1.09); C500(0.89)  LDD1639  [9]
 LDCM0436  CL46 HEK-293T C492(1.06)  LDD1034  [8]
 LDCM0437  CL47 HEK-293T C492(0.85)  LDD1035  [8]
 LDCM0438  CL48 HEK-293T C492(0.91)  LDD1036  [8]
 LDCM0439  CL49 HEK-293T C492(0.92)  LDD1037  [8]
 LDCM0440  CL5 HEK-293T C475(1.07); C125(1.09); C500(0.94); C492(1.03)  LDD1644  [9]
 LDCM0441  CL50 HEK-293T C492(0.77)  LDD1039  [8]
 LDCM0442  CL51 HEK-293T C492(0.83)  LDD1040  [8]
 LDCM0443  CL52 HEK-293T C492(0.89)  LDD1041  [8]
 LDCM0444  CL53 HEK-293T C492(0.95)  LDD1042  [8]
 LDCM0445  CL54 HEK-293T C492(0.79)  LDD1043  [8]
 LDCM0446  CL55 HEK-293T C492(0.86)  LDD1044  [8]
 LDCM0447  CL56 HEK-293T C492(0.84)  LDD1045  [8]
 LDCM0448  CL57 HEK-293T C492(0.98)  LDD1046  [8]
 LDCM0449  CL58 HEK-293T C492(0.89)  LDD1047  [8]
 LDCM0450  CL59 HEK-293T C492(0.95)  LDD1048  [8]
 LDCM0451  CL6 HEK-293T C475(0.99); C374(1.01); C500(1.27); C492(0.88)  LDD1654  [9]
 LDCM0452  CL60 HEK-293T C492(0.85)  LDD1050  [8]
 LDCM0453  CL61 HEK-293T C475(0.89); C374(0.96); C500(0.91); C492(0.90)  LDD1656  [9]
 LDCM0454  CL62 HEK-293T C475(0.99); C374(1.21); C500(0.66); C492(1.07)  LDD1657  [9]
 LDCM0455  CL63 HEK-293T C475(0.98)  LDD1658  [9]
 LDCM0456  CL64 HEK-293T C475(1.00); C374(1.35); C500(1.93); C492(0.96)  LDD1659  [9]
 LDCM0457  CL65 HEK-293T C475(0.99); C125(1.04); C500(0.86); C492(0.97)  LDD1660  [9]
 LDCM0458  CL66 HEK-293T C475(1.03); C374(0.97); C500(1.28); C492(1.23)  LDD1661  [9]
 LDCM0459  CL67 HEK-293T C475(1.02); C125(1.14); C500(0.91); C492(1.01)  LDD1662  [9]
 LDCM0460  CL68 HEK-293T C475(1.04); C125(0.95)  LDD1663  [9]
 LDCM0461  CL69 HEK-293T C475(1.11); C374(1.12); C125(0.97); C500(1.19)  LDD1664  [9]
 LDCM0462  CL7 HEK-293T C475(0.96); C125(1.16); C500(1.04); C492(0.98)  LDD1665  [9]
 LDCM0463  CL70 HEK-293T C475(0.85); C125(1.09); C500(0.75)  LDD1666  [9]
 LDCM0464  CL71 HEK-293T C475(1.05); C500(0.70); C492(1.03)  LDD1667  [9]
 LDCM0465  CL72 HEK-293T C475(1.16); C125(1.10); C492(0.97)  LDD1668  [9]
 LDCM0466  CL73 HEK-293T C475(1.08); C374(1.02); C500(0.77); C492(0.92)  LDD1669  [9]
 LDCM0467  CL74 HEK-293T C475(0.93); C374(1.38); C500(1.03); C492(0.92)  LDD1670  [9]
 LDCM0469  CL76 HEK-293T C475(0.99); C374(1.14); C500(1.11); C492(0.93)  LDD1672  [9]
 LDCM0470  CL77 HEK-293T C475(1.16); C125(1.21); C500(0.88); C492(0.93)  LDD1673  [9]
 LDCM0471  CL78 HEK-293T C475(1.02); C374(0.98); C500(1.06); C492(1.17)  LDD1674  [9]
 LDCM0472  CL79 HEK-293T C475(1.09); C125(1.09); C500(1.09); C492(0.94)  LDD1675  [9]
 LDCM0473  CL8 HEK-293T C475(1.02); C125(1.32)  LDD1676  [9]
 LDCM0474  CL80 HEK-293T C475(0.91); C125(0.92)  LDD1677  [9]
 LDCM0475  CL81 HEK-293T C475(1.10); C374(1.10); C125(1.14); C500(1.07)  LDD1678  [9]
 LDCM0476  CL82 HEK-293T C475(0.99); C125(0.98); C500(0.81)  LDD1679  [9]
 LDCM0477  CL83 HEK-293T C475(1.17); C500(0.84); C492(0.64)  LDD1680  [9]
 LDCM0478  CL84 HEK-293T C475(0.96); C125(1.35); C492(0.93)  LDD1681  [9]
 LDCM0479  CL85 HEK-293T C475(0.94); C374(0.99); C500(1.37); C492(1.07)  LDD1682  [9]
 LDCM0480  CL86 HEK-293T C475(0.94); C374(1.14); C500(1.10); C492(1.15)  LDD1683  [9]
 LDCM0481  CL87 HEK-293T C475(1.02)  LDD1684  [9]
 LDCM0482  CL88 HEK-293T C475(0.96); C374(1.02); C500(1.16); C492(1.22)  LDD1685  [9]
 LDCM0483  CL89 HEK-293T C475(1.03); C125(1.14); C500(0.88); C492(0.97)  LDD1686  [9]
 LDCM0484  CL9 HEK-293T C475(1.21); C374(1.10); C125(1.01); C500(0.80)  LDD1687  [9]
 LDCM0485  CL90 HEK-293T C475(1.25); C374(1.14); C500(0.76); C492(1.12)  LDD1688  [9]
 LDCM0486  CL91 HEK-293T C492(1.27)  LDD1084  [8]
 LDCM0487  CL92 HEK-293T C492(1.00)  LDD1085  [8]
 LDCM0488  CL93 HEK-293T C492(1.04)  LDD1086  [8]
 LDCM0489  CL94 HEK-293T C492(1.17)  LDD1087  [8]
 LDCM0490  CL95 HEK-293T C492(0.97)  LDD1088  [8]
 LDCM0491  CL96 HEK-293T C492(1.09)  LDD1089  [8]
 LDCM0492  CL97 HEK-293T C492(1.06)  LDD1090  [8]
 LDCM0493  CL98 HEK-293T C492(1.00)  LDD1091  [8]
 LDCM0494  CL99 HEK-293T C492(0.92)  LDD1092  [8]
 LDCM0495  E2913 HEK-293T C475(1.08)  LDD1698  [9]
 LDCM0468  Fragment33 HEK-293T C475(1.02)  LDD1671  [9]
 LDCM0427  Fragment51 HEK-293T C475(0.91); C374(1.12); C500(0.78); C492(1.01)  LDD1631  [9]
 LDCM0022  KB02 HEK-293T C475(0.89); C374(0.94); C500(0.85); C492(0.88)  LDD1492  [9]
 LDCM0023  KB03 HEK-293T C475(1.02); C374(0.97); C500(1.16); C492(0.95)  LDD1497  [9]
 LDCM0024  KB05 SK-MEL-28 C374(2.34)  LDD3427  [4]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C475(0.51)  LDD2099  [5]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6 (PLPP6) PA-phosphatase related phosphoesterase family Q8IY26
Transporter and channel
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Myelin and lymphocyte protein (MAL) MAL family P21145
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF (STRIT1) . P0DN84
Other
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
Cortexin-3 (CTXN3) Cortexin family Q4LDR2
Neuronal vesicle trafficking-associated protein 1 (NSG1) NSG family P42857

References

1 Design and synthesis of tailored human caseinolytic protease P inhibitors. Chem Commun (Camb). 2018 Aug 28;54(70):9833-9836. doi: 10.1039/c8cc05265d.
Mass spectrometry data entry: PXD010277
2 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
3 A chemical proteomics approach for global mapping of functional lysines on cell surface of living cell. Nat Commun. 2024 Apr 8;15(1):2997. doi: 10.1038/s41467-024-47033-w.
Mass spectrometry data entry: PXD042888
4 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
5 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
6 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
7 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
8 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
9 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402