Details of the Probe

General Information of Probe

Probe ID
LDPC0537
Probe Name
C310
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 421.467
Lipid-water partition coefficient (xlogp) 3.4291
Rotatable Bond Count (rotbonds) 9
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C21H26F3N5O
Canonical SMILES
[H]C#CC([H])([H])C([H])([H])C1(C([H])([H])C([H])([H])C(=O)N([H])C([H])([H])c2c([H])c(C(F)(F)F)c([H])c([H])c2N2C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C2([H])[H])N=N1
InChI
InChI=1S/C21H26F3N5O/c1-3-4-8-20(26-27-20)9-7-19(30)25-15-16-14-17(21(22,23)24)5-6-18(16)29-12-10-28(2)11-13-29/h1,5-6,14H,4,7-13,15H2,2H3,(H,25,30)
InChIKey
UAKVZCBTXDRHBP-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

160 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-hydroxyacyl-CoA lyase 2 (ILVBL) LDTP00032 7.78  LDD1977 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 41.07  LDD1977 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 15.78  LDD1977 
Acid ceramidase (ASAH1) LDTP05905 8.94  LDD1977 
Activin receptor type-1B (ACVR1B) LDTP03822 33.36  LDD1977 
Adipocyte plasma membrane-associated protein (APMAP) LDTP12293 9.58  LDD1977 
ADP-dependent glucokinase (ADPGK) LDTP11127 31.56  LDD1977 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 18.51  LDD1977 
Alpha-galactosidase A (GLA) LDTP02141 26.72  LDD1977 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 15.03  LDD1977 
Antigen peptide transporter 1 (TAP1) LDTP05408 11.88  LDD1977 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 9.32  LDD1977 
Atlastin-2 (ATL2) LDTP09251 7.89  LDD1977 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 15.89  LDD1977 
ATP-dependent RNA helicase DHX29 (DHX29) LDTP08064 7.78  LDD1977 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 7.52  LDD1977 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 12.30  LDD1977 
Beta-galactosidase (GLB1) LDTP02837 22.47  LDD1977 
Beta-glucuronidase (GUSB) LDTP02260 11.71  LDD1977 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 22.47  LDD1977 
Beta-hexosaminidase subunit beta (HEXB) LDTP02216 12.73  LDD1977 
Beta-mannosidase (MANBA) LDTP00282 19.70  LDD1977 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 19.16  LDD1977 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 17.51  LDD1977 
Carboxypeptidase D (CPD) LDTP01372 19.56  LDD1977 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 8.51  LDD1977 
Catechol O-methyltransferase (COMT) LDTP03145 12.04  LDD1977 
Cathepsin B (CTSB) LDTP02223 33.59  LDD1977 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 13.45  LDD1977 
Ceramide glucosyltransferase (UGCG) LDTP06617 18.25  LDD1977 
Ceramide kinase (CERK) LDTP09391 12.82  LDD1977 
Ceramide synthase 1 (CERS1) LDTP03394 8.51  LDD1977 
Ceramide synthase 2 (CERS2) LDTP10329 22.01  LDD1977 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 7.73  LDD1977 
Choline kinase alpha (CHKA) LDTP03787 12.47  LDD1977 
COP9 signalosome complex subunit 3 (COPS3) LDTP13675 7.84  LDD1977 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 12.47  LDD1977 
Copper-transporting ATPase 1 (ATP7A) LDTP05422 12.91  LDD1977 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 23.75  LDD1977 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 14.12  LDD1977 
Cytochrome b5 type B (CYB5B) LDTP00697 45.25  LDD1977 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 8.34  LDD1977 
Deoxyribonuclease-2-alpha (DNASE2) LDTP00185 24.42  LDD1977 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 12.64  LDD1977 
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) LDTP02362 19.03  LDD1977 
Dipeptidyl peptidase 1 (CTSC) LDTP04572 14.52  LDD1977 
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) LDTP11259 11.96  LDD1977 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 8.00  LDD1977 
E3 ubiquitin-protein ligase Itchy homolog (ITCH) LDTP10441 9.99  LDD1977 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 9.78  LDD1977 
EH domain-containing protein 4 (EHD4) LDTP11788 8.28  LDD1977 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 9.58  LDD1977 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 9.32  LDD1977 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 14.12  LDD1977 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 19.43  LDD1977 
Ephrin type-A receptor 7 (EPHA7) LDTP06370 30.27  LDD1977 
Epidermal growth factor receptor (EGFR) LDTP01785 8.63  LDD1977 
Gamma-glutamyl hydrolase (GGH) LDTP09886 14.42  LDD1977 
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) LDTP06721 7.62  LDD1977 
Glutathione S-transferase A4 (GSTA4) LDTP00575 7.94  LDD1977 
Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) LDTP17305 26.54  LDD1977 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 18.90  LDD1977 
GPI-anchor transamidase (PIGK) LDTP09835 8.57  LDD1977 
GTP-binding protein SAR1a (SAR1A) LDTP12470 9.92  LDD1977 
GTP-binding protein SAR1b (SAR1B) LDTP14231 9.13  LDD1977 
Helicase MOV-10 (MOV10) LDTP12233 8.63  LDD1977 
Heme A synthase COX15 (COX15) LDTP07931 16.34  LDD1977 
Heme oxygenase 1 (HMOX1) LDTP02359 17.15  LDD1977 
Heme oxygenase 2 (HMOX2) LDTP03540 14.93  LDD1977 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 35.02  LDD1977 
Heparanase (HPSE) LDTP13804 12.21  LDD1977 
Hexokinase-2 (HK2) LDTP04531 11.00  LDD1977 
Holocytochrome c-type synthase (HCCS) LDTP04581 10.13  LDD1977 
Immunity-related GTPase family Q protein (IRGQ) LDTP19838 8.06  LDD1977 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 17.63  LDD1977 
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (AASDHPPT) LDTP12524 9.71  LDD1977 
Lactadherin (MFGE8) LDTP05561 10.13  LDD1977 
Legumain (LGMN) LDTP10888 13.09  LDD1977 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 16.80  LDD1977 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 7.84  LDD1977 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 9.71  LDD1977 
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) LDTP03858 8.75  LDD1977 
Lysosomal acid phosphatase (ACP2) LDTP02539 21.26  LDD1977 
Lysosomal alpha-glucosidase (GAA) LDTP02486 20.11  LDD1977 
Lysosomal alpha-mannosidase (MAN2B1) LDTP00338 14.12  LDD1977 
Lysosomal protective protein (CTSA) LDTP02505 16.45  LDD1977 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 40.50  LDD1977 
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (MAN1A1) LDTP03677 9.06  LDD1977 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 9.65  LDD1977 
Minor histocompatibility antigen H13 (HM13) LDTP09396 8.06  LDD1977 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 13.93  LDD1977 
N-alpha-acetyltransferase 40 (NAA40) LDTP08265 20.11  LDD1977 
N-lysine methyltransferase SMYD2 (SMYD2) LDTP12509 7.78  LDD1977 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 13.45  LDD1977 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 13.27  LDD1977 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 21.41  LDD1977 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 7.67  LDD1977 
NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) LDTP01219 13.64  LDD1977 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 20.97  LDD1977 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 10.56  LDD1977 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 9.00  LDD1977 
NADPH--cytochrome P450 reductase (POR) LDTP02848 8.00  LDD1977 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 11.16  LDD1977 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 25.46  LDD1977 
Palmitoyltransferase ZDHHC13 (ZDHHC13) LDTP08455 10.13  LDD1977 
Peptidyl-glycine alpha-amidating monooxygenase (PAM) LDTP02976 24.42  LDD1977 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 17.39  LDD1977 
Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) LDTP01562 14.93  LDD1977 
Phosphatidylinositol 4-kinase type 2-alpha (PI4K2A) LDTP11209 10.27  LDD1977 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 9.45  LDD1977 
Phospholipase A2 group XV (PLA2G15) LDTP09088 9.58  LDD1977 
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (PHKA1) LDTP04080 8.46  LDD1977 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 21.26  LDD1977 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 14.22  LDD1977 
Polypeptide N-acetylgalactosaminyltransferase 2 (GALNT2) LDTP05623 8.69  LDD1977 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 11.88  LDD1977 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 10.85  LDD1977 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 9.38  LDD1977 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 9.58  LDD1977 
Protein disulfide-isomerase (P4HB) LDTP02188 7.62  LDD1977 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 8.57  LDD1977 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 13.55  LDD1977 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 10.48  LDD1977 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 11.88  LDD1977 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 21.86  LDD1977 
Rab-like protein 3 (RABL3) LDTP06986 14.32  LDD1977 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 11.16  LDD1977 
Ras-related GTP-binding protein C (RRAGC) LDTP12166 8.17  LDD1977 
Ras-related protein Rab-1A (RAB1A) LDTP05006 7.67  LDD1977 
Ras-related protein Rab-24 (RAB24) LDTP10020 7.67  LDD1977 
Ras-related protein Rab-5B (RAB5B) LDTP04893 14.72  LDD1977 
Ras-related protein Rab-5C (RAB5C) LDTP04398 7.62  LDD1977 
Ras-related protein Ral-A (RALA) LDTP02557 11.31  LDD1977 
Receptor-type tyrosine-protein phosphatase F (PTPRF) LDTP02499 11.96  LDD1977 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 16.22  LDD1977 
Retinol dehydrogenase 13 (RDH13) LDTP09061 11.63  LDD1977 
Ribitol 5-phosphate transferase FKRP (FKRP) LDTP12109 15.35  LDD1977 
Ribonuclease T2 (RNASET2) LDTP00316 28.05  LDD1977 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 8.28  LDD1977 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 13.00  LDD1977 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 8.00  LDD1977 
Serine/threonine-protein kinase tousled-like 2 (TLK2) LDTP08226 25.28  LDD1977 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 8.57  LDD1977 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 8.63  LDD1977 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 17.75  LDD1977 
Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) LDTP02067 7.73  LDD1977 
Soluble calcium-activated nucleotidase 1 (CANT1) LDTP09620 11.55  LDD1977 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 7.67  LDD1977 
Squalene monooxygenase (SQLE) LDTP06142 9.78  LDD1977 
Sulfhydryl oxidase 2 (QSOX2) LDTP07813 12.30  LDD1977 
Thiol S-methyltransferase TMT1A (TMT1A) LDTP12056 12.73  LDD1977 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 7.62  LDD1977 
Tissue alpha-L-fucosidase (FUCA1) LDTP02006 27.47  LDD1977 
Torsin-1B (TOR1B) LDTP00400 7.89  LDD1977 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 18.90  LDD1977 
Ubiquitin thioesterase OTUB1 (OTUB1) LDTP10318 44.94  LDD1977 
UDP-glucuronic acid decarboxylase 1 (UXS1) LDTP09074 11.00  LDD1977 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 8.22  LDD1977 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 7.94  LDD1977 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 11.79  LDD1977 
------------------------------------------------------------------------------------
⏷ Show the Full List of 160 Enzyme
131 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 16.45  LDD1977 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 23.26  LDD1977 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 19.56  LDD1977 
ADP/ATP translocase 2 (SLC25A5) LDTP02087 7.73  LDD1977 
ADP/ATP translocase 3 (SLC25A6) LDTP02609 19.29  LDD1977 
Amino acid transporter heavy chain SLC3A2 (SLC3A2) LDTP02256 8.75  LDD1977 
Amyloid-beta precursor protein (APP) LDTP02071 32.45  LDD1977 
Anion exchange protein 2 (SLC4A2) LDTP02061 10.27  LDD1977 
Anoctamin-6 (ANO6) LDTP06855 11.63  LDD1977 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 10.85  LDD1977 
BRI3-binding protein (BRI3BP) LDTP15648 15.67  LDD1977 
Cation-dependent mannose-6-phosphate receptor (M6PR) LDTP03061 9.13  LDD1977 
Cation-independent mannose-6-phosphate receptor (IGF2R) LDTP02586 18.90  LDD1977 
Cell cycle control protein 50A (TMEM30A) LDTP12665 19.16  LDD1977 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 7.89  LDD1977 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 49.52  LDD1977 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 9.19  LDD1977 
Derlin-1 (DERL1) LDTP11245 9.99  LDD1977 
EH domain-containing protein 1 (EHD1) LDTP11934 7.94  LDD1977 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 29.45  LDD1977 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 10.63  LDD1977 
Flotillin-1 (FLOT1) LDTP01366 8.11  LDD1977 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 12.13  LDD1977 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 12.13  LDD1977 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 11.79  LDD1977 
H(+)/Cl(-) exchange transporter 7 (CLCN7) LDTP04463 10.56  LDD1977 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 21.71  LDD1977 
Importin-9 (IPO9) LDTP10663 15.14  LDD1977 
Integral membrane protein 2B (ITM2B) LDTP13833 37.01  LDD1977 
Integral membrane protein 2C (ITM2C) LDTP12451 24.76  LDD1977 
Integrin alpha-V (ITGAV) LDTP02166 13.36  LDD1977 
Intraflagellar transport protein 56 (IFT56) LDTP00010 7.62  LDD1977 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 8.69  LDD1977 
Low-density lipoprotein receptor (LDLR) LDTP01829 13.74  LDD1977 
Low-density lipoprotein receptor-related protein 2 (LRP2) LDTP05218 13.36  LDD1977 
Lysosomal-associated transmembrane protein 4A (LAPTM4A) LDTP06275 30.06  LDD1977 
Lysosome membrane protein 2 (SCARB2) LDTP06034 12.55  LDD1977 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 18.13  LDD1977 
Major facilitator superfamily domain-containing protein 8 (MFSD8) LDTP09261 9.58  LDD1977 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 8.57  LDD1977 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 15.89  LDD1977 
Metal cation symporter ZIP14 (SLC39A14) LDTP06293 7.62  LDD1977 
Metal transporter CNNM3 (CNNM3) LDTP09144 12.73  LDD1977 
Metaxin-1 (MTX1) LDTP05900 36.25  LDD1977 
Methylosome subunit pICln (CLNS1A) LDTP04597 8.34  LDD1977 
MICOS complex subunit MIC26 (APOO) LDTP11250 10.63  LDD1977 
MICOS complex subunit MIC60 (IMMT) LDTP06660 7.52  LDD1977 
Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) LDTP07472 8.69  LDD1977 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 8.46  LDD1977 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 7.67  LDD1977 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 18.90  LDD1977 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 8.17  LDD1977 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 31.78  LDD1977 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 46.53  LDD1977 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 14.42  LDD1977 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 38.59  LDD1977 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 14.22  LDD1977 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 11.47  LDD1977 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 10.63  LDD1977 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 9.45  LDD1977 
Mpv17-like protein 2 (MPV17L2) LDTP14952 11.08  LDD1977 
Neuropilin-1 (NRP1) LDTP00433 7.57  LDD1977 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 14.72  LDD1977 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 10.85  LDD1977 
Nucleoporin NDC1 (NDC1) LDTP11213 13.83  LDD1977 
Nucleoporin Nup37 (NUP37) LDTP09203 8.11  LDD1977 
Occludin (OCLN) LDTP06581 17.15  LDD1977 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 9.85  LDD1977 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 9.65  LDD1977 
Podocalyxin (PODXL) LDTP00321 16.11  LDD1977 
Prolow-density lipoprotein receptor-related protein 1 (LRP1) LDTP05538 18.90  LDD1977 
Prosaposin (PSAP) LDTP02215 36.76  LDD1977 
Protein ARV1 (ARV1) LDTP11812 20.82  LDD1977 
Protein Mpv17 (MPV17) LDTP03869 10.70  LDD1977 
Protein tweety homolog 3 (TTYH3) LDTP11615 37.27  LDD1977 
Protein YIPF3 (YIPF3) LDTP11626 13.18  LDD1977 
Proton-activated chloride channel (PACC1) LDTP12042 20.68  LDD1977 
Proton-coupled amino acid transporter 1 (SLC36A1) LDTP08016 11.55  LDD1977 
Proton-transporting V-type ATPase complex assembly regulator TMEM9 (TMEM9) LDTP12981 24.08  LDD1977 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 17.63  LDD1977 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 12.47  LDD1977 
Renin receptor (ATP6AP2) LDTP01309 8.88  LDD1977 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 8.22  LDD1977 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 16.11  LDD1977 
Secretory carrier-associated membrane protein 3 (SCAMP3) LDTP00451 8.00  LDD1977 
Sideroflexin-4 (SFXN4) LDTP07531 9.00  LDD1977 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 9.51  LDD1977 
Slit homolog 2 protein (SLIT2) LDTP01427 12.73  LDD1977 
Sodium bicarbonate cotransporter 3 (SLC4A7) LDTP14275 7.67  LDD1977 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 10.93  LDD1977 
Sodium/hydrogen exchanger 6 (SLC9A6) LDTP09807 12.55  LDD1977 
Solute carrier family 12 member 2 (SLC12A2) LDTP04653 7.78  LDD1977 
Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) LDTP02544 11.63  LDD1977 
Solute carrier family 2, facilitated glucose transporter member 4 (SLC2A4) LDTP02740 9.38  LDD1977 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 20.25  LDD1977 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 20.11  LDD1977 
Sortilin (SORT1) LDTP10885 22.01  LDD1977 
Sortilin-related receptor (SORL1) LDTP09838 25.46  LDD1977 
StAR-related lipid transfer protein 3 (STARD3) LDTP06221 26.17  LDD1977 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 17.75  LDD1977 
Surfeit locus protein 4 (SURF4) LDTP00592 12.04  LDD1977 
Syntaxin-3 (STX3) LDTP05811 15.67  LDD1977 
Syntaxin-5 (STX5) LDTP05780 12.13  LDD1977 
Syntenin-1 (SDCBP) LDTP00310 14.52  LDD1977 
Tetraspanin-10 (TSPAN10) LDTP15967 14.32  LDD1977 
Tetraspanin-3 (TSPAN3) LDTP16813 46.21  LDD1977 
Transferrin receptor protein 1 (TFRC) LDTP01969 29.45  LDD1977 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 12.47  LDD1977 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 28.64  LDD1977 
Transmembrane 9 superfamily member 2 (TM9SF2) LDTP15845 34.06  LDD1977 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 14.52  LDD1977 
Transmembrane 9 superfamily member 4 (TM9SF4) LDTP09789 8.88  LDD1977 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 8.00  LDD1977 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 8.75  LDD1977 
Transmembrane protein 126A (TMEM126A) LDTP15948 18.77  LDD1977 
Transmembrane protein 160 (TMEM160) LDTP20002 25.99  LDD1977 
Transmembrane protein 199 (TMEM199) LDTP08881 10.56  LDD1977 
Transmembrane protein 214 (TMEM214) LDTP07477 8.63  LDD1977 
Transmembrane protein 230 (TMEM230) LDTP10065 12.91  LDD1977 
Transmembrane protein 59 (TMEM59) LDTP11406 25.99  LDD1977 
Transmembrane protein 87A (TMEM87A) LDTP15481 26.54  LDD1977 
Transportin-1 (TNPO1) LDTP09949 8.57  LDD1977 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 14.52  LDD1977 
V-type proton ATPase subunit E 1 (ATP6V1E1) LDTP03811 7.89  LDD1977 
V-type proton ATPase subunit S1 (ATP6AP1) LDTP06499 12.73  LDD1977 
Vang-like protein 1 (VANGL1) LDTP09288 14.22  LDD1977 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 15.78  LDD1977 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 17.03  LDD1977 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 11.47  LDD1977 
Wolframin (WFS1) LDTP01380 8.00  LDD1977 
Zinc transporter 7 (SLC30A7) LDTP09180 31.12  LDD1977 
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⏷ Show the Full List of 131 Transporter and channel
1 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 8.57  LDD1977 
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1 GPCR Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adhesion G protein-coupled receptor E5 (ADGRE5) LDTP04221 19.43  LDD1977 
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10 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 12.04  LDD1977 
Butyrophilin subfamily 2 member A1 (BTN2A1) LDTP07927 8.11  LDD1977 
CD276 antigen (CD276) LDTP07280 15.35  LDD1977 
Cell surface glycoprotein MUC18 (MCAM) LDTP04020 11.79  LDD1977 
HLA class I histocompatibility antigen, A alpha chain (HLA-A) LDTP02040 19.16  LDD1977 
HLA class I histocompatibility antigen, B alpha chain (HLA-B) LDTP01913 8.82  LDD1977 
HLA class I histocompatibility antigen, C alpha chain (HLA-C) LDTP02491 14.72  LDD1977 
Junctional adhesion molecule A (F11R) LDTP14203 8.46  LDD1977 
Kin of IRRE-like protein 1 (KIRREL1) LDTP10445 11.55  LDD1977 
Leukocyte surface antigen CD47 (CD47) LDTP05572 16.56  LDD1977 
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⏷ Show the Full List of 10 Immunoglobulin
1 Cytokine and receptor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Interferon gamma receptor 1 (IFNGR1) LDTP02775 36.25  LDD1977 
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116 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
60S ribosomal export protein NMD3 (NMD3) LDTP10200 37.53  LDD1977 
Amyloid beta precursor like protein 2 (APLP2) LDTP05491 22.16  LDD1977 
Angio-associated migratory cell protein (AAMP) LDTP05966 9.25  LDD1977 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 11.71  LDD1977 
Apolipoprotein B-100 (APOB) LDTP02013 16.22  LDD1977 
Apolipoprotein L2 (APOL2) LDTP11076 17.63  LDD1977 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 8.82  LDD1977 
C-type mannose receptor 2 (MRC2) LDTP13114 22.63  LDD1977 
Calcium-binding and coiled-coil domain-containing protein 2 (CALCOCO2) LDTP05764 18.77  LDD1977 
Calmodulin-3 (CALM3) LDTP02443 9.13  LDD1977 
Calumenin (CALU) LDTP00887 24.42  LDD1977 
cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) LDTP02511 13.55  LDD1977 
CD2 antigen cytoplasmic tail-binding protein 2 (CD2BP2) LDTP01589 7.52  LDD1977 
CD302 antigen (CD302) LDTP08581 67.18  LDD1977 
Centrin-2 (CETN2) LDTP03926 18.51  LDD1977 
Collectin-12 (COLEC12) LDTP07031 18.13  LDD1977 
COP9 signalosome complex subunit 8 (COPS8) LDTP10927 7.94  LDD1977 
CYFIP-related Rac1 interactor B (CYRIB) LDTP12642 13.18  LDD1977 
Cysteine and glycine-rich protein 2 (CSRP2) LDTP06542 7.89  LDD1977 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 20.53  LDD1977 
DDB1- and CUL4-associated factor 7 (DCAF7) LDTP04947 8.63  LDD1977 
DDRGK domain-containing protein 1 (DDRGK1) LDTP10403 8.51  LDD1977 
Desmocollin-3 (DSC3) LDTP06154 12.21  LDD1977 
Desmoglein-2 (DSG2) LDTP06042 10.48  LDD1977 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 24.93  LDD1977 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 23.26  LDD1977 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 34.54  LDD1977 
Endothelial protein C receptor (PROCR) LDTP13669 17.63  LDD1977 
Engulfment and cell motility protein 2 (ELMO2) LDTP10469 13.18  LDD1977 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 62.68  LDD1977 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 76.64  LDD1977 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 11.39  LDD1977 
FRAS1-related extracellular matrix protein 2 (FREM2) LDTP07080 22.01  LDD1977 
Galectin-3-binding protein (LGALS3BP) LDTP05558 14.83  LDD1977 
Ganglioside GM2 activator (GM2A) LDTP02927 20.68  LDD1977 
Golgi apparatus protein 1 (GLG1) LDTP09920 18.90  LDD1977 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 18.13  LDD1977 
Golgi membrane protein 1 (GOLM1) LDTP09054 19.97  LDD1977 
Golgi phosphoprotein 3-like (GOLPH3L) LDTP11910 14.62  LDD1977 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 8.17  LDD1977 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 11.88  LDD1977 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 37.53  LDD1977 
Kinetochore protein Nuf2 (NUF2) LDTP11525 7.57  LDD1977 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 8.88  LDD1977 
Laminin subunit beta-1 (LAMB1) LDTP02230 9.06  LDD1977 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 24.76  LDD1977 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 13.83  LDD1977 
Membralin (TMEM259) LDTP14939 9.92  LDD1977 
Membrane cofactor protein (CD46) LDTP02795 11.79  LDD1977 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 11.47  LDD1977 
Microtubule-associated protein RP/EB family member 2 (MAPRE2) LDTP06413 11.79  LDD1977 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 10.70  LDD1977 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 70.52  LDD1977 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 54.57  LDD1977 
Myelin expression factor 2 (MYEF2) LDTP13060 7.67  LDD1977 
Negative elongation factor C/D (NELFCD) LDTP08594 7.57  LDD1977 
Next to BRCA1 gene 1 protein (NBR1) LDTP06159 20.25  LDD1977 
Nicastrin (NCSTN) LDTP09787 12.82  LDD1977 
Nidogen-1 (NID1) LDTP02728 17.88  LDD1977 
Nonsense-mediated mRNA decay factor SMG5 (SMG5) LDTP13712 8.69  LDD1977 
Nucleobindin-1 (NUCB1) LDTP05375 8.88  LDD1977 
Nucleobindin-2 (NUCB2) LDTP05160 53.82  LDD1977 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 20.97  LDD1977 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 16.68  LDD1977 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 7.62  LDD1977 
Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) LDTP11906 13.83  LDD1977 
Plexin-B2 (PLXNB2) LDTP00513 19.70  LDD1977 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 22.94  LDD1977 
Proteasome activator complex subunit 3 (PSME3) LDTP04917 7.84  LDD1977 
Protein angel homolog 1 (ANGEL1) LDTP16249 9.19  LDD1977 
Protein CEBPZOS (CEBPZOS) LDTP18883 19.70  LDD1977 
Protein CREG1 (CREG1) LDTP01279 50.91  LDD1977 
Protein CutA (CUTA) LDTP01075 14.42  LDD1977 
Protein FAM114A2 (FAM114A2) LDTP16080 23.59  LDD1977 
Protein FAM162A (FAM162A) LDTP10056 16.68  LDD1977 
Protein FAM177A1 (FAM177A1) LDTP15398 9.32  LDD1977 
Protein FAM234B (FAM234B) LDTP18732 12.38  LDD1977 
Protein GOLM2 (GOLM2) LDTP15115 27.86  LDD1977 
Protein LYRIC (MTDH) LDTP08224 30.70  LDD1977 
Protein YIF1A (YIF1A) LDTP01494 9.32  LDD1977 
Rab3 GTPase-activating protein catalytic subunit (RAB3GAP1) LDTP06292 8.82  LDD1977 
Rac GTPase-activating protein 1 (RACGAP1) LDTP11712 8.88  LDD1977 
RAD50-interacting protein 1 (RINT1) LDTP07476 8.06  LDD1977 
Ragulator complex protein LAMTOR1 (LAMTOR1) LDTP07401 7.84  LDD1977 
Reticulocalbin-2 (RCN2) LDTP06097 24.76  LDD1977 
Reticulon-3 (RTN3) LDTP01522 27.47  LDD1977 
Reticulon-4 (RTN4) LDTP12412 24.59  LDD1977 
Seizure 6-like protein 2 (SEZ6L2) LDTP07703 17.51  LDD1977 
Sequestosome-1 (SQSTM1) LDTP05898 54.95  LDD1977 
Serine incorporator 1 (SERINC1) LDTP12544 26.35  LDD1977 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 9.71  LDD1977 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 18.77  LDD1977 
Surfeit locus protein 1 (SURF1) LDTP06404 7.62  LDD1977 
Synaptic vesicle glycoprotein 2A (SV2A) LDTP07934 21.71  LDD1977 
Synaptogyrin-2 (SYNGR2) LDTP00859 8.22  LDD1977 
Syntaxin-10 (STX10) LDTP00986 49.87  LDD1977 
Syntaxin-12 (STX12) LDTP08389 11.55  LDD1977 
Syntaxin-18 (STX18) LDTP13086 17.03  LDD1977 
Syntaxin-7 (STX7) LDTP00632 14.52  LDD1977 
Syntaxin-8 (STX8) LDTP13664 8.94  LDD1977 
Tax1-binding protein 1 (TAX1BP1) LDTP08294 27.28  LDD1977 
Testis-expressed protein 264 (TEX264) LDTP14259 7.78  LDD1977 
Tetraspanin-6 (TSPAN6) LDTP14458 25.81  LDD1977 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 8.51  LDD1977 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 21.56  LDD1977 
TraB domain-containing protein (TRABD) LDTP19963 10.13  LDD1977 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 64.45  LDD1977 
Transducin beta-like protein 2 (TBL2) LDTP16285 7.89  LDD1977 
Trophoblast glycoprotein (TPBG) LDTP05960 13.64  LDD1977 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 10.78  LDD1977 
U6 snRNA-associated Sm-like protein LSm3 (LSM3) LDTP04979 10.34  LDD1977 
Uncharacterized protein KIAA2013 (KIAA2013) LDTP17652 15.67  LDD1977 
Very low-density lipoprotein receptor (VLDLR) LDTP05215 27.86  LDD1977 
Vesicle-associated membrane protein 7 (VAMP7) LDTP04468 8.34  LDD1977 
WW domain-binding protein 2 (WBP2) LDTP10033 9.25  LDD1977 
Zinc finger CCHC domain-containing protein 3 (ZCCHC3) LDTP12623 15.78  LDD1977 
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⏷ Show the Full List of 116 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1977 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587