Details of the Target
General Information of Target
| Target ID | LDTP01279 | |||||
|---|---|---|---|---|---|---|
| Target Name | Protein CREG1 (CREG1) |
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| Gene Name | CREG1 | |||||
| Gene ID | 8804 | |||||
| Synonyms |
CREG; Protein CREG1; Cellular repressor of E1A-stimulated genes 1 |
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| 3D Structure | ||||||
| Sequence |
MAGLSRGSARALLAALLASTLLALLVSPARGRGGRDHGDWDEASRLPPLPPREDAARVAR
FVTHVSDWGALATISTLEAVRGRPFADVLSLSDGPPGAGSGVPYFYLSPLQLSVSNLQEN PYATLTMTLAQTNFCKKHGFDPQSPLCVHIMLSGTVTKVNETEMDIAKHSLFIRHPEMKT WPSSHNWFFAKLNITNIWVLDYFGGPKIVTPEEYYNVTVQ |
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| Target Bioclass |
Other
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| Family |
CREG family
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| Subcellular location |
Secreted
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| Function |
May contribute to the transcriptional control of cell growth and differentiation. Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein. The transcriptional control activity of cell growth requires interaction with IGF2R.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
ABPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
Alkylaryl probe 1 Probe Info |
 |
20.00 | LDD0387 | [1] | |
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STPyne Probe Info |
 |
K137(0.63); K179(16.43) | LDD2217 | [2] | |
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IA-alkyne Probe Info |
 |
N.A. | LDD0162 | [3] | |
PAL-AfBPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
C169 Probe Info |
 |
22.94 | LDD1849 | [4] | |
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C170 Probe Info |
 |
54.95 | LDD1850 | [4] | |
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C171 Probe Info |
 |
19.29 | LDD1851 | [4] | |
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C282 Probe Info |
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23.92 | LDD1952 | [4] | |
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C302 Probe Info |
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15.67 | LDD1971 | [4] | |
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C305 Probe Info |
 |
14.12 | LDD1974 | [4] | |
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C310 Probe Info |
 |
50.91 | LDD1977 | [4] | |
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C313 Probe Info |
 |
39.95 | LDD1980 | [4] | |
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C314 Probe Info |
 |
33.36 | LDD1981 | [4] | |
References