Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C310  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 160 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00697  Cytochrome b5 type B (CYB5B) 45.3
 LDTP10318  Ubiquitin thioesterase OTUB1 (OTUB1) 44.9
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 41.1
 LDTP13620  Lysosomal thioesterase PPT2 (PPT2) 40.5
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 35.0
 LDTP02223  Cathepsin B (CTSB) 33.6
 LDTP03822  Activin receptor type-1B (ACVR1B) 33.4
 LDTP11127  ADP-dependent glucokinase (ADPGK) 31.6
 LDTP06370  Ephrin type-A receptor 7 (EPHA7) 30.3
 LDTP00316  Ribonuclease T2 (RNASET2) 28.1
 LDTP02006  Tissue alpha-L-fucosidase (FUCA1) 27.5
 LDTP02141  Alpha-galactosidase A (GLA) 26.7
 LDTP17305  Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) 26.5
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 25.5
 LDTP08226  Serine/threonine-protein kinase tousled-like 2 (TLK2) 25.3
 LDTP00185  Deoxyribonuclease-2-alpha (DNASE2) 24.4
 LDTP02976  Peptidyl-glycine alpha-amidating monooxygenase (PAM) 24.4
 LDTP00486  Cytochrome b-c1 complex subunit 8 (UQCRQ) 23.8
 LDTP02837  Beta-galactosidase (GLB1) 22.5
 LDTP02169  Beta-hexosaminidase subunit alpha (HEXA) 22.5
 LDTP10329  Ceramide synthase 2 (CERS2) 22.0
 LDTP09256  Putative phospholipase B-like 2 (PLBD2) 21.9
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 21.4
 LDTP02539  Lysosomal acid phosphatase (ACP2) 21.3
 LDTP11215  Plasma alpha-L-fucosidase (FUCA2) 21.3
 LDTP00832  NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) 21.0
 LDTP02486  Lysosomal alpha-glucosidase (GAA) 20.1
 LDTP08265  N-alpha-acetyltransferase 40 (NAA40) 20.1
 LDTP00282  Beta-mannosidase (MANBA) 19.7
 LDTP01372  Carboxypeptidase D (CPD) 19.6
 LDTP04008  Endothelin-converting enzyme 1 (ECE1) 19.4
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) 19.2
 LDTP02362  Dihydrolipoyl dehydrogenase, mitochondrial (DLD) 19.0
 LDTP12763  Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) 18.9
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1) 18.9
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 18.5
 LDTP06617  Ceramide glucosyltransferase (UGCG) 18.3
 LDTP09395  Signal peptide peptidase-like 2A (SPPL2A) 17.8
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 17.6
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 17.5
 LDTP14218  Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) 17.4
 LDTP02359  Heme oxygenase 1 (HMOX1) 17.1
 LDTP13358  Leucyl-cystinyl aminopeptidase (LNPEP) 16.8
 LDTP02505  Lysosomal protective protein (CTSA) 16.4
 LDTP07931  Heme A synthase COX15 (COX15) 16.3
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 16.2
 LDTP06618  ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) 15.9
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 15.8
 LDTP12109  Ribitol 5-phosphate transferase FKRP (FKRP) 15.3
 LDTP04634  Alpha-N-acetylglucosaminidase (NAGLU) 15.0
 LDTP03540  Heme oxygenase 2 (HMOX2) 14.9
 LDTP01562  Peptidyl-prolyl cis-trans isomerase FKBP9 (FKBP9) 14.9
 LDTP04893  Ras-related protein Rab-5B (RAB5B) 14.7
 LDTP04572  Dipeptidyl peptidase 1 (CTSC) 14.5
 LDTP09886  Gamma-glutamyl hydrolase (GGH) 14.4
 LDTP06986  Rab-like protein 3 (RABL3) 14.3
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 14.2
 LDTP13189  Cytochrome b-c1 complex subunit 9 (UQCR10) 14.1
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 14.1
 LDTP00338  Lysosomal alpha-mannosidase (MAN2B1) 14.1
 LDTP02799  N-acetylglucosamine-6-sulfatase (GNS) 13.9
 LDTP01219  NADH dehydrogenase 1 beta subcomplex subunit 1 (NDUFB1) 13.6
 LDTP04247  Protein farnesyltransferase subunit beta (FNTB) 13.5
 LDTP12873  CDGSH iron-sulfur domain-containing protein 1 (CISD1) 13.5
 LDTP11273  N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) 13.5
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 13.3
 LDTP10888  Legumain (LGMN) 13.1
 LDTP02860  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) 13.0
 LDTP05422  Copper-transporting ATPase 1 (ATP7A) 12.9
 LDTP09391  Ceramide kinase (CERK) 12.8
 LDTP02216  Beta-hexosaminidase subunit beta (HEXB) 12.7
 LDTP12056  Thiol S-methyltransferase TMT1A (TMT1A) 12.7
 LDTP18087  Dephospho-CoA kinase domain-containing protein (DCAKD) 12.6
 LDTP03787  Choline kinase alpha (CHKA) 12.5
 LDTP11187  COP9 signalosome complex subunit 4 (COPS4) 12.5
 LDTP00783  Beta-1,4-glucuronyltransferase 1 (B4GAT1) 12.3
 LDTP07813  Sulfhydryl oxidase 2 (QSOX2) 12.3
 LDTP13804  Heparanase (HPSE) 12.2
 LDTP03145  Catechol O-methyltransferase (COMT) 12.0
 LDTP11259  Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) 12.0
 LDTP02499  Receptor-type tyrosine-protein phosphatase F (PTPRF) 12.0
 LDTP05408  Antigen peptide transporter 1 (TAP1) 11.9
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 11.9
 LDTP04712  Puromycin-sensitive aminopeptidase (NPEPPS) 11.9
 LDTP03854  Vitamin K-dependent gamma-carboxylase (GGCX) 11.8
 LDTP02260  Beta-glucuronidase (GUSB) 11.7
 LDTP09061  Retinol dehydrogenase 13 (RDH13) 11.6
 LDTP09620  Soluble calcium-activated nucleotidase 1 (CANT1) 11.6
 LDTP02557  Ras-related protein Ral-A (RALA) 11.3
 LDTP04051  Nicotinamide phosphoribosyltransferase (NAMPT) 11.2
 LDTP03608  RAC-beta serine/threonine-protein kinase (AKT2) 11.2
 LDTP04531  Hexokinase-2 (HK2) 11.0
 LDTP09074  UDP-glucuronic acid decarboxylase 1 (UXS1) 11.0
 LDTP15988  Probable serine carboxypeptidase CPVL (CPVL) 10.9
 LDTP14276  NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) 10.6
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 10.5
 LDTP11209  Phosphatidylinositol 4-kinase type 2-alpha (PI4K2A) 10.3
 LDTP04581  Holocytochrome c-type synthase (HCCS) 10.1
 LDTP05561  Lactadherin (MFGE8) 10.1
 LDTP08455  Palmitoyltransferase ZDHHC13 (ZDHHC13) 10.1
 LDTP10441  E3 ubiquitin-protein ligase Itchy homolog (ITCH) 10.0
 LDTP12470  GTP-binding protein SAR1a (SAR1A) 9.9
 LDTP10699  E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) 9.8
 LDTP06142  Squalene monooxygenase (SQLE) 9.8
 LDTP12524  L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (AASDHPPT) 9.7
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1) 9.7
 LDTP04730  Methionine--tRNA ligase, cytoplasmic (MARS1) 9.6
 LDTP12293  Adipocyte plasma membrane-associated protein (APMAP) 9.6
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 9.6
 LDTP09088  Phospholipase A2 group XV (PLA2G15) 9.6
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 9.6
 LDTP13220  Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) 9.4
 LDTP04884  Proteasome subunit alpha type-6 (PSMA6) 9.4
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 9.3
 LDTP12868  Endoplasmic reticulum aminopeptidase 1 (ERAP1) 9.3
 LDTP14231  GTP-binding protein SAR1b (SAR1B) 9.1
 LDTP03677  Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (MAN1A1) 9.1
 LDTP01982  NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) 9.0
 LDTP05905  Acid ceramidase (ASAH1) 8.9
 LDTP03858  Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) 8.8
 LDTP05623  Polypeptide N-acetylgalactosaminyltransferase 2 (GALNT2) 8.7
 LDTP01785  Epidermal growth factor receptor (EGFR) 8.6
 LDTP12233  Helicase MOV-10 (MOV10) 8.6
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 8.6
 LDTP09835  GPI-anchor transamidase (PIGK) 8.6
 LDTP10471  Protein disulfide-isomerase TMX3 (TMX3) 8.6
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 8.6
 LDTP03257  Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) 8.5
 LDTP03394  Ceramide synthase 1 (CERS1) 8.5
 LDTP04080  Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (PHKA1) 8.5
 LDTP06200  Delta(14)-sterol reductase LBR (LBR) 8.3
 LDTP11788  EH domain-containing protein 4 (EHD4) 8.3
 LDTP15484  Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) 8.3
 LDTP14030  V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) 8.2
 LDTP12166  Ras-related GTP-binding protein C (RRAGC) 8.2
 LDTP19838  Immunity-related GTPase family Q protein (IRGQ) 8.1
 LDTP09396  Minor histocompatibility antigen H13 (HM13) 8.1
 LDTP00950  Dynamin-like 120 kDa protein, mitochondrial (OPA1) 8.0
 LDTP02848  NADPH--cytochrome P450 reductase (POR) 8.0
 LDTP00597  Serine palmitoyltransferase 1 (SPTLC1) 8.0
 LDTP00575  Glutathione S-transferase A4 (GSTA4) 7.9
 LDTP12867  Very-long-chain enoyl-CoA reductase (TECR) 7.9
 LDTP09251  Atlastin-2 (ATL2) 7.9
 LDTP00400  Torsin-1B (TOR1B) 7.9
 LDTP13675  COP9 signalosome complex subunit 3 (COPS3) 7.8
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 7.8
 LDTP00032  2-hydroxyacyl-CoA lyase 2 (ILVBL) 7.8
 LDTP08064  ATP-dependent RNA helicase DHX29 (DHX29) 7.8
 LDTP12509  N-lysine methyltransferase SMYD2 (SMYD2) 7.8
 LDTP11178  Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) 7.7
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) 7.7
 LDTP12959  NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) 7.7
 LDTP05006  Ras-related protein Rab-1A (RAB1A) 7.7
 LDTP10020  Ras-related protein Rab-24 (RAB24) 7.7
 LDTP01613  Sphingosine-1-phosphate lyase 1 (SGPL1) 7.7
 LDTP06721  GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) 7.6
 LDTP02188  Protein disulfide-isomerase (P4HB) 7.6
 LDTP04398  Ras-related protein Rab-5C (RAB5C) 7.6
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 7.6
 LDTP12681  ATPase family AAA domain-containing protein 3A (ATAD3A) 7.5
Transporter and channel
Click to Show/Hide to Show 131 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 49.5
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 46.5
 LDTP16813  Tetraspanin-3 (TSPAN3) 46.2
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 38.6
 LDTP11615  Protein tweety homolog 3 (TTYH3) 37.3
 LDTP13833  Integral membrane protein 2B (ITM2B) 37.0
 LDTP02215  Prosaposin (PSAP) 36.8
 LDTP05900  Metaxin-1 (MTX1) 36.3
 LDTP15845  Transmembrane 9 superfamily member 2 (TM9SF2) 34.1
 LDTP02071  Amyloid-beta precursor protein (APP) 32.4
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 31.8
 LDTP09180  Zinc transporter 7 (SLC30A7) 31.1
 LDTP06275  Lysosomal-associated transmembrane protein 4A (LAPTM4A) 30.1
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 29.4
 LDTP01969  Transferrin receptor protein 1 (TFRC) 29.4
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 28.6
 LDTP15481  Transmembrane protein 87A (TMEM87A) 26.5
 LDTP06221  StAR-related lipid transfer protein 3 (STARD3) 26.2
 LDTP20002  Transmembrane protein 160 (TMEM160) 26.0
 LDTP11406  Transmembrane protein 59 (TMEM59) 26.0
 LDTP09838  Sortilin-related receptor (SORL1) 25.5
 LDTP12451  Integral membrane protein 2C (ITM2C) 24.8
 LDTP12981  Proton-transporting V-type ATPase complex assembly regulator TMEM9 (TMEM9) 24.1
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 23.3
 LDTP10885  Sortilin (SORT1) 22.0
 LDTP03559  High affinity cationic amino acid transporter 1 (SLC7A1) 21.7
 LDTP11812  Protein ARV1 (ARV1) 20.8
 LDTP12042  Proton-activated chloride channel (PACC1) 20.7
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 20.3
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 20.1
 LDTP02608  ADP/ATP translocase 1 (SLC25A4) 19.6
 LDTP02609  ADP/ATP translocase 3 (SLC25A6) 19.3
 LDTP12665  Cell cycle control protein 50A (TMEM30A) 19.2
 LDTP02586  Cation-independent mannose-6-phosphate receptor (IGF2R) 18.9
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 18.9
 LDTP05538  Prolow-density lipoprotein receptor-related protein 1 (LRP1) 18.9
 LDTP15948  Transmembrane protein 126A (TMEM126A) 18.8
 LDTP02562  Lysosome-associated membrane glycoprotein 1 (LAMP1) 18.1
 LDTP01671  STARD3 N-terminal-like protein (STARD3NL) 17.8
 LDTP12207  Putative divalent cation/proton antiporter TMEM165 (TMEM165) 17.6
 LDTP06581  Occludin (OCLN) 17.1
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 17.0
 LDTP11116  45 kDa calcium-binding protein (SDF4) 16.4
 LDTP00321  Podocalyxin (PODXL) 16.1
 LDTP00547  Secretory carrier-associated membrane protein 2 (SCAMP2) 16.1
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 15.9
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 15.8
 LDTP15648  BRI3-binding protein (BRI3BP) 15.7
 LDTP05811  Syntaxin-3 (STX3) 15.7
 LDTP10663  Importin-9 (IPO9) 15.1
 LDTP00541  NPC intracellular cholesterol transporter 1 (NPC1) 14.7
 LDTP00310  Syntenin-1 (SDCBP) 14.5
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 14.5
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 14.5
 LDTP00477  Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) 14.4
 LDTP15967  Tetraspanin-10 (TSPAN10) 14.3
 LDTP14200  Mitochondrial ornithine transporter 1 (SLC25A15) 14.2
 LDTP09288  Vang-like protein 1 (VANGL1) 14.2
 LDTP11213  Nucleoporin NDC1 (NDC1) 13.8
 LDTP01829  Low-density lipoprotein receptor (LDLR) 13.7
 LDTP02166  Integrin alpha-V (ITGAV) 13.4
 LDTP05218  Low-density lipoprotein receptor-related protein 2 (LRP2) 13.4
 LDTP11626  Protein YIPF3 (YIPF3) 13.2
 LDTP10065  Transmembrane protein 230 (TMEM230) 12.9
 LDTP09144  Metal transporter CNNM3 (CNNM3) 12.7
 LDTP01427  Slit homolog 2 protein (SLIT2) 12.7
 LDTP06499  V-type proton ATPase subunit S1 (ATP6AP1) 12.7
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 12.6
 LDTP09807  Sodium/hydrogen exchanger 6 (SLC9A6) 12.6
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 12.5
 LDTP06426  Translocating chain-associated membrane protein 1 (TRAM1) 12.5
 LDTP01542  Golgi SNAP receptor complex member 1 (GOSR1) 12.1
 LDTP11869  Growth hormone-inducible transmembrane protein (GHITM) 12.1
 LDTP05780  Syntaxin-5 (STX5) 12.1
 LDTP00592  Surfeit locus protein 4 (SURF4) 12.0
 LDTP04459  H(+)/Cl(-) exchange transporter 3 (CLCN3) 11.8
 LDTP06855  Anoctamin-6 (ANO6) 11.6
 LDTP02544  Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) 11.6
 LDTP08016  Proton-coupled amino acid transporter 1 (SLC36A1) 11.6
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 11.5
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 11.5
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 11.1
 LDTP10731  Sodium-coupled neutral amino acid symporter 2 (SLC38A2) 10.9
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 10.9
 LDTP04940  NPC intracellular cholesterol transporter 2 (NPC2) 10.9
 LDTP03869  Protein Mpv17 (MPV17) 10.7
 LDTP08878  ER membrane protein complex subunit 5 (MMGT1) 10.6
 LDTP11250  MICOS complex subunit MIC26 (APOO) 10.6
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 10.6
 LDTP04463  H(+)/Cl(-) exchange transporter 7 (CLCN7) 10.6
 LDTP08881  Transmembrane protein 199 (TMEM199) 10.6
 LDTP02061  Anion exchange protein 2 (SLC4A2) 10.3
 LDTP11245  Derlin-1 (DERL1) 10.0
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 9.8
 LDTP03905  Peroxisomal biogenesis factor 19 (PEX19) 9.6
 LDTP09261  Major facilitator superfamily domain-containing protein 8 (MFSD8) 9.6
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 9.5
 LDTP12210  Mitochondrial thiamine pyrophosphate carrier (SLC25A19) 9.4
 LDTP02740  Solute carrier family 2, facilitated glucose transporter member 4 (SLC2A4) 9.4
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 9.2
 LDTP03061  Cation-dependent mannose-6-phosphate receptor (M6PR) 9.1
 LDTP07531  Sideroflexin-4 (SFXN4) 9.0
 LDTP01309  Renin receptor (ATP6AP2) 8.9
 LDTP09789  Transmembrane 9 superfamily member 4 (TM9SF4) 8.9
 LDTP02256  Amino acid transporter heavy chain SLC3A2 (SLC3A2) 8.8
 LDTP13969  Transmembrane emp24 domain-containing protein 7 (TMED7) 8.8
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 8.7
 LDTP07472  Mitochondrial adenyl nucleotide antiporter SLC25A24 (SLC25A24) 8.7
 LDTP07477  Transmembrane protein 214 (TMEM214) 8.6
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 8.6
 LDTP09949  Transportin-1 (TNPO1) 8.6
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 8.5
 LDTP04597  Methylosome subunit pICln (CLNS1A) 8.3
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 8.2
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 8.2
 LDTP01366  Flotillin-1 (FLOT1) 8.1
 LDTP09203  Nucleoporin Nup37 (NUP37) 8.1
 LDTP00451  Secretory carrier-associated membrane protein 3 (SCAMP3) 8.0
 LDTP06365  Transmembrane emp24 domain-containing protein 2 (TMED2) 8.0
 LDTP01380  Wolframin (WFS1) 8.0
 LDTP11934  EH domain-containing protein 1 (EHD1) 7.9
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 7.9
 LDTP03811  V-type proton ATPase subunit E 1 (ATP6V1E1) 7.9
 LDTP04653  Solute carrier family 12 member 2 (SLC12A2) 7.8
 LDTP02087  ADP/ATP translocase 2 (SLC25A5) 7.7
 LDTP14235  Mitochondrial carrier homolog 2 (MTCH2) 7.7
 LDTP14275  Sodium bicarbonate cotransporter 3 (SLC4A7) 7.7
 LDTP00010  Intraflagellar transport protein 56 (IFT56) 7.6
 LDTP06293  Metal cation symporter ZIP14 (SLC39A14) 7.6
 LDTP00433  Neuropilin-1 (NRP1) 7.6
 LDTP06660  MICOS complex subunit MIC60 (IMMT) 7.5
Transcription factor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 8.6
GPCR
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP04221  Adhesion G protein-coupled receptor E5 (ADGRE5) 19.4
Immunoglobulin
Click to Show/Hide to Show 10 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP02040  HLA class I histocompatibility antigen, A alpha chain (HLA-A) 19.2
 LDTP05572  Leukocyte surface antigen CD47 (CD47) 16.6
 LDTP07280  CD276 antigen (CD276) 15.3
 LDTP02491  HLA class I histocompatibility antigen, C alpha chain (HLA-C) 14.7
 LDTP03772  Basigin (BSG) 12.0
 LDTP04020  Cell surface glycoprotein MUC18 (MCAM) 11.8
 LDTP10445  Kin of IRRE-like protein 1 (KIRREL1) 11.6
 LDTP01913  HLA class I histocompatibility antigen, B alpha chain (HLA-B) 8.8
 LDTP14203  Junctional adhesion molecule A (F11R) 8.5
 LDTP07927  Butyrophilin subfamily 2 member A1 (BTN2A1) 8.1
Cytokine and receptor
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP02775  Interferon gamma receptor 1 (IFNGR1) 36.3
Other
Click to Show/Hide to Show 116 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP00850  ER lumen protein-retaining receptor 3 (KDELR3) 76.6
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 70.5
 LDTP08581  CD302 antigen (CD302) 67.2
 LDTP00779  Trans-Golgi network integral membrane protein 2 (TGOLN2) 64.4
 LDTP03678  ER lumen protein-retaining receptor 2 (KDELR2) 62.7
 LDTP05898  Sequestosome-1 (SQSTM1) 54.9
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 54.6
 LDTP05160  Nucleobindin-2 (NUCB2) 53.8
 LDTP01279  Protein CREG1 (CREG1) 50.9
 LDTP00986  Syntaxin-10 (STX10) 49.9
 LDTP10200  60S ribosomal export protein NMD3 (NMD3) 37.5
 LDTP19780  Keratinocyte-associated transmembrane protein 2 (KCT2) 37.5
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 34.5
 LDTP08224  Protein LYRIC (MTDH) 30.7
 LDTP15115  Protein GOLM2 (GOLM2) 27.9
 LDTP05215  Very low-density lipoprotein receptor (VLDLR) 27.9
 LDTP01522  Reticulon-3 (RTN3) 27.5
 LDTP08294  Tax1-binding protein 1 (TAX1BP1) 27.3
 LDTP12544  Serine incorporator 1 (SERINC1) 26.4
 LDTP14458  Tetraspanin-6 (TSPAN6) 25.8
 LDTP08689  Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) 24.9
 LDTP15240  LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) 24.8
 LDTP06097  Reticulocalbin-2 (RCN2) 24.8
 LDTP12412  Reticulon-4 (RTN4) 24.6
 LDTP00887  Calumenin (CALU) 24.4
 LDTP16080  Protein FAM114A2 (FAM114A2) 23.6
 LDTP19021  EF-hand calcium-binding domain-containing protein 14 (EFCAB14) 23.3
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 22.9
 LDTP13114  C-type mannose receptor 2 (MRC2) 22.6
 LDTP05491  Amyloid beta precursor like protein 2 (APLP2) 22.2
 LDTP07080  FRAS1-related extracellular matrix protein 2 (FREM2) 22.0
 LDTP07934  Synaptic vesicle glycoprotein 2A (SV2A) 21.7
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 21.6
 LDTP04684  Nucleosome assembly protein 1-like 1 (NAP1L1) 21.0
 LDTP02927  Ganglioside GM2 activator (GM2A) 20.7
 LDTP13902  Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) 20.5
 LDTP06159  Next to BRCA1 gene 1 protein (NBR1) 20.3
 LDTP09054  Golgi membrane protein 1 (GOLM1) 20.0
 LDTP00513  Plexin-B2 (PLXNB2) 19.7
 LDTP18883  Protein CEBPZOS (CEBPZOS) 19.7
 LDTP09920  Golgi apparatus protein 1 (GLG1) 18.9
 LDTP05764  Calcium-binding and coiled-coil domain-containing protein 2 (CALCOCO2) 18.8
 LDTP03352  Splicing factor U2AF 65 kDa subunit (U2AF2) 18.8
 LDTP03926  Centrin-2 (CETN2) 18.5
 LDTP07031  Collectin-12 (COLEC12) 18.1
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 18.1
 LDTP02728  Nidogen-1 (NID1) 17.9
 LDTP11076  Apolipoprotein L2 (APOL2) 17.6
 LDTP13669  Endothelial protein C receptor (PROCR) 17.6
 LDTP07703  Seizure 6-like protein 2 (SEZ6L2) 17.5
 LDTP13086  Syntaxin-18 (STX18) 17.0
 LDTP10965  Nucleosome assembly protein 1-like 4 (NAP1L4) 16.7
 LDTP10056  Protein FAM162A (FAM162A) 16.7
 LDTP02013  Apolipoprotein B-100 (APOB) 16.2
 LDTP12623  Zinc finger CCHC domain-containing protein 3 (ZCCHC3) 15.8
 LDTP17652  Uncharacterized protein KIAA2013 (KIAA2013) 15.7
 LDTP05558  Galectin-3-binding protein (LGALS3BP) 14.8
 LDTP11910  Golgi phosphoprotein 3-like (GOLPH3L) 14.6
 LDTP00632  Syntaxin-7 (STX7) 14.5
 LDTP01075  Protein CutA (CUTA) 14.4
 LDTP13606  Mammalian ependymin-related protein 1 (EPDR1) 13.8
 LDTP11906  Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) 13.8
 LDTP05960  Trophoblast glycoprotein (TPBG) 13.6
 LDTP02511  cAMP-dependent protein kinase type I-alpha regulatory subunit (PRKAR1A) 13.5
 LDTP12642  CYFIP-related Rac1 interactor B (CYRIB) 13.2
 LDTP10469  Engulfment and cell motility protein 2 (ELMO2) 13.2
 LDTP09787  Nicastrin (NCSTN) 12.8
 LDTP18732  Protein FAM234B (FAM234B) 12.4
 LDTP06154  Desmocollin-3 (DSC3) 12.2
 LDTP04207  Heat shock 70 kDa protein 13 (HSPA13) 11.9
 LDTP02795  Membrane cofactor protein (CD46) 11.8
 LDTP06413  Microtubule-associated protein RP/EB family member 2 (MAPRE2) 11.8
 LDTP08364  Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) 11.7
 LDTP08389  Syntaxin-12 (STX12) 11.6
 LDTP07274  MICOS complex subunit MIC13 (MICOS13) 11.5
 LDTP04652  Eukaryotic translation initiation factor 5 (EIF5) 11.4
 LDTP13922  Tudor and KH domain-containing protein (TDRKH) 10.8
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 10.7
 LDTP06042  Desmoglein-2 (DSG2) 10.5
 LDTP04979  U6 snRNA-associated Sm-like protein LSm3 (LSM3) 10.3
 LDTP19963  TraB domain-containing protein (TRABD) 10.1
 LDTP14939  Membralin (TMEM259) 9.9
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 9.7
 LDTP15398  Protein FAM177A1 (FAM177A1) 9.3
 LDTP01494  Protein YIF1A (YIF1A) 9.3
 LDTP05966  Angio-associated migratory cell protein (AAMP) 9.3
 LDTP10033  WW domain-binding protein 2 (WBP2) 9.3
 LDTP16249  Protein angel homolog 1 (ANGEL1) 9.2
 LDTP02443  Calmodulin-3 (CALM3) 9.1
 LDTP02230  Laminin subunit beta-1 (LAMB1) 9.1
 LDTP13664  Syntaxin-8 (STX8) 8.9
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 8.9
 LDTP05375  Nucleobindin-1 (NUCB1) 8.9
 LDTP11712  Rac GTPase-activating protein 1 (RACGAP1) 8.9
 LDTP11389  Bcl-2-like protein 13 (BCL2L13) 8.8
 LDTP06292  Rab3 GTPase-activating protein catalytic subunit (RAB3GAP1) 8.8
 LDTP13712  Nonsense-mediated mRNA decay factor SMG5 (SMG5) 8.7
 LDTP04947  DDB1- and CUL4-associated factor 7 (DCAF7) 8.6
 LDTP10403  DDRGK domain-containing protein 1 (DDRGK1) 8.5
 LDTP07368  Tetratricopeptide repeat protein 19, mitochondrial (TTC19) 8.5
 LDTP04468  Vesicle-associated membrane protein 7 (VAMP7) 8.3
 LDTP00859  Synaptogyrin-2 (SYNGR2) 8.2
 LDTP01466  HAUS augmin-like complex subunit 5 (HAUS5) 8.2
 LDTP07476  RAD50-interacting protein 1 (RINT1) 8.1
 LDTP10927  COP9 signalosome complex subunit 8 (COPS8) 7.9
 LDTP06542  Cysteine and glycine-rich protein 2 (CSRP2) 7.9
 LDTP16285  Transducin beta-like protein 2 (TBL2) 7.9
 LDTP04917  Proteasome activator complex subunit 3 (PSME3) 7.8
 LDTP07401  Ragulator complex protein LAMTOR1 (LAMTOR1) 7.8
 LDTP14259  Testis-expressed protein 264 (TEX264) 7.8
 LDTP13060  Myelin expression factor 2 (MYEF2) 7.7
 LDTP12755  OCIA domain-containing protein 1 (OCIAD1) 7.6
 LDTP06404  Surfeit locus protein 1 (SURF1) 7.6
 LDTP11525  Kinetochore protein Nuf2 (NUF2) 7.6
 LDTP08594  Negative elongation factor C/D (NELFCD) 7.6
 LDTP01589  CD2 antigen cytoplasmic tail-binding protein 2 (CD2BP2) 7.5

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587