General Information of Target

Target ID LDTP06270
Target Name Signal peptidase complex subunit 2 (SPCS2)
Gene Name SPCS2
Gene ID 9789
Synonyms
KIAA0102; SPC25; Signal peptidase complex subunit 2; Microsomal signal peptidase 25 kDa subunit; SPase 25 kDa subunit
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MAAAAVQGGRSGGSGGCSGAGGASNCGTGSGRSGLLDKWKIDDKPVKIDKWDGSAVKNSL
DDSAKKVLLEKYKYVENFGLIDGRLTICTISCFFAIVALIWDYMHPFPESKPVLALCVIS
YFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDIWQLSSSLKRFDDKYTLKLTFISGR
TKQQREAEFTKSIAKFFDHSGTLVMDAYEPEISRLHDSLAIERKIK
Target Bioclass
Enzyme
Family
SPCS2 family
Subcellular location
Endoplasmic reticulum membrane
Function
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site.
Uniprot ID
Q15005
Ensemble ID
ENST00000263672.11
HGNC ID
HGNC:28962

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 38 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info 
12.40  LDD0402  [1]
HDSF-alk
 Probe Info 
1.88  LDD0197  [2]
DA-P2
 Probe Info 
26.01  LDD0348  [3]
HRP
 Probe Info 
20.63  LDD0347  [3]
CHEMBL5175495
 Probe Info 
6.91  LDD0196  [4]
CY-1
 Probe Info 
100.00  LDD0243  [5]
W1
 Probe Info 
21.93  LDD0235  [6]
FBP2
 Probe Info 
2.17  LDD0317  [7]
ONAyne
 Probe Info 
K71(0.40)  LDD0274  [8]
STPyne
 Probe Info 
K169(0.63); K191(9.43); K38(10.00); K40(9.72)  LDD0277  [8]
P12
 Probe Info 
19.96  LDD0202  [9]
JZ128-DTB
 Probe Info 
C26(0.00); C17(0.00)  LDD0462  [10]
BTD
 Probe Info 
C26(1.05)  LDD1700  [11]
Sulforaphane-probe2
 Probe Info 
2.94  LDD0042  [12]
AHL-Pu-1
 Probe Info 
C26(2.55); C17(2.67)  LDD0171  [13]
DBIA
 Probe Info 
C17(5.30); C26(1.35)  LDD0080  [14]
ATP probe
 Probe Info 
K191(0.00); K195(0.00)  LDD0199  [15]
IA-alkyne
 Probe Info 
N.A.  LDD0162  [16]
Lodoacetamide azide
 Probe Info 
C26(0.00); C17(0.00)  LDD0037  [17]
ATP probe
 Probe Info 
N.A.  LDD0035  [18]
NAIA_4
 Probe Info 
N.A.  LDD2226  [19]
NAIA_5
 Probe Info 
C17(0.00); C26(0.00)  LDD2224  [19]
TFBX
 Probe Info 
C17(0.00); C26(0.00)  LDD0027  [20]
WYneN
 Probe Info 
N.A.  LDD0021  [21]
DA-P3
 Probe Info 
N.A.  LDD0178  [3]
aHNE
 Probe Info 
C26(0.00); C17(0.00)  LDD0001  [21]
Compound 10
 Probe Info 
C17(0.00); C26(0.00)  LDD2216  [22]
Compound 11
 Probe Info 
C17(0.00); C26(0.00)  LDD2213  [22]
ENE
 Probe Info 
C17(0.00); C26(0.00)  LDD0006  [21]
IPM
 Probe Info 
C17(0.00); C26(0.00)  LDD0005  [21]
NHS
 Probe Info 
N.A.  LDD0010  [21]
VSF
 Probe Info 
C17(0.00); C26(0.00)  LDD0007  [21]
Phosphinate-6
 Probe Info 
N.A.  LDD0018  [23]
Acrolein
 Probe Info 
C17(0.00); H216(0.00); C26(0.00)  LDD0217  [24]
Crotonaldehyde
 Probe Info 
C17(0.00); H216(0.00); C26(0.00); H144(0.00)  LDD0219  [24]
Methacrolein
 Probe Info 
C17(0.00); C26(0.00)  LDD0218  [24]
AOyne
 Probe Info 
15.00  LDD0443  [25]
TPP-AC
 Probe Info 
N.A.  LDD0427  [26]
PAL-AfBPP Probe
Click To Hide/Show 52 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
DR-1
 Probe Info 
3.19  LDD0398  [27]
C022
 Probe Info 
6.92  LDD1728  [28]
C040
 Probe Info 
10.34  LDD1740  [28]
C055
 Probe Info 
12.91  LDD1752  [28]
C056
 Probe Info 
24.93  LDD1753  [28]
C091
 Probe Info 
19.84  LDD1782  [28]
C092
 Probe Info 
34.06  LDD1783  [28]
C094
 Probe Info 
56.49  LDD1785  [28]
C112
 Probe Info 
18.64  LDD1799  [28]
C134
 Probe Info 
28.64  LDD1816  [28]
C153
 Probe Info 
14.72  LDD1834  [28]
C161
 Probe Info 
10.34  LDD1841  [28]
C169
 Probe Info 
23.10  LDD1849  [28]
C187
 Probe Info 
20.68  LDD1865  [28]
C198
 Probe Info 
10.63  LDD1874  [28]
C201
 Probe Info 
29.24  LDD1877  [28]
C210
 Probe Info 
72.00  LDD1884  [28]
C218
 Probe Info 
21.11  LDD1892  [28]
C220
 Probe Info 
14.22  LDD1894  [28]
C228
 Probe Info 
20.11  LDD1901  [28]
C231
 Probe Info 
25.28  LDD1904  [28]
C235
 Probe Info 
30.91  LDD1908  [28]
C238
 Probe Info 
13.55  LDD1911  [28]
C243
 Probe Info 
10.93  LDD1916  [28]
C246
 Probe Info 
14.83  LDD1919  [28]
C252
 Probe Info 
9.99  LDD1925  [28]
C264
 Probe Info 
18.64  LDD1935  [28]
C275
 Probe Info 
5.58  LDD1945  [28]
C277
 Probe Info 
7.57  LDD1947  [28]
C278
 Probe Info 
74.03  LDD1948  [28]
C285
 Probe Info 
28.64  LDD1955  [28]
C287
 Probe Info 
11.31  LDD1957  [28]
C289
 Probe Info 
77.17  LDD1959  [28]
C299
 Probe Info 
6.19  LDD1968  [28]
C310
 Probe Info 
8.63  LDD1977  [28]
C339
 Probe Info 
4.96  LDD2002  [28]
C349
 Probe Info 
11.08  LDD2010  [28]
C350
 Probe Info 
27.67  LDD2011  [28]
C362
 Probe Info 
35.75  LDD2023  [28]
C388
 Probe Info 
71.51  LDD2047  [28]
C390
 Probe Info 
29.45  LDD2049  [28]
C403
 Probe Info 
17.88  LDD2061  [28]
C407
 Probe Info 
12.82  LDD2064  [28]
FFF probe11
 Probe Info 
20.00  LDD0471  [29]
FFF probe13
 Probe Info 
20.00  LDD0475  [29]
FFF probe14
 Probe Info 
16.52  LDD0477  [29]
FFF probe15
 Probe Info 
13.45  LDD0478  [29]
FFF probe2
 Probe Info 
13.59  LDD0463  [29]
FFF probe3
 Probe Info 
20.00  LDD0464  [29]
STS-1
 Probe Info 
N.A.  LDD0137  [30]
DFG-out-4
 Probe Info 
4.80  LDD0075  [31]
OEA-DA
 Probe Info 
13.36  LDD0046  [32]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C26(0.75); C17(1.02)  LDD2142  [11]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C26(0.58); C17(1.02)  LDD2112  [11]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C26(0.62); C17(0.58)  LDD2117  [11]
 LDCM0026  4SU-RNA+native RNA DM93 C26(2.55); C17(2.67)  LDD0171  [13]
 LDCM0214  AC1 HCT 116 C17(1.16); C26(1.11)  LDD0531  [14]
 LDCM0215  AC10 HCT 116 C17(1.17); C26(1.13)  LDD0532  [14]
 LDCM0216  AC100 HCT 116 C17(1.43); C26(1.44)  LDD0533  [14]
 LDCM0217  AC101 HCT 116 C17(1.52); C26(1.53)  LDD0534  [14]
 LDCM0218  AC102 HCT 116 C17(1.09); C26(1.06)  LDD0535  [14]
 LDCM0219  AC103 HCT 116 C17(1.34); C26(1.31)  LDD0536  [14]
 LDCM0220  AC104 HCT 116 C17(0.99); C26(0.96)  LDD0537  [14]
 LDCM0221  AC105 HCT 116 C17(1.34); C26(1.33)  LDD0538  [14]
 LDCM0222  AC106 HCT 116 C17(1.88); C26(1.81)  LDD0539  [14]
 LDCM0223  AC107 HCT 116 C17(1.26); C26(1.12)  LDD0540  [14]
 LDCM0224  AC108 HCT 116 C17(1.11); C26(1.07)  LDD0541  [14]
 LDCM0225  AC109 HCT 116 C17(1.15); C26(2.08)  LDD0542  [14]
 LDCM0226  AC11 HCT 116 C17(1.57); C26(1.36)  LDD0543  [14]
 LDCM0227  AC110 HCT 116 C17(1.12); C26(1.34)  LDD0544  [14]
 LDCM0228  AC111 HCT 116 C17(1.16); C26(1.30)  LDD0545  [14]
 LDCM0229  AC112 HCT 116 C17(1.42); C26(1.30)  LDD0546  [14]
 LDCM0230  AC113 HCT 116 C17(1.09); C26(1.12)  LDD0547  [14]
 LDCM0231  AC114 HCT 116 C17(0.85); C26(1.23)  LDD0548  [14]
 LDCM0232  AC115 HCT 116 C17(1.00); C26(1.31)  LDD0549  [14]
 LDCM0233  AC116 HCT 116 C17(1.11); C26(1.75)  LDD0550  [14]
 LDCM0234  AC117 HCT 116 C17(1.04); C26(1.30)  LDD0551  [14]
 LDCM0235  AC118 HCT 116 C17(0.90); C26(1.15)  LDD0552  [14]
 LDCM0236  AC119 HCT 116 C17(1.21); C26(1.17)  LDD0553  [14]
 LDCM0237  AC12 HCT 116 C17(1.23); C26(1.16)  LDD0554  [14]
 LDCM0238  AC120 HCT 116 C17(1.04); C26(1.02)  LDD0555  [14]
 LDCM0239  AC121 HCT 116 C17(0.89); C26(0.94)  LDD0556  [14]
 LDCM0240  AC122 HCT 116 C17(1.07); C26(1.02)  LDD0557  [14]
 LDCM0241  AC123 HCT 116 C17(0.95); C26(1.11)  LDD0558  [14]
 LDCM0242  AC124 HCT 116 C17(0.92); C26(1.01)  LDD0559  [14]
 LDCM0243  AC125 HCT 116 C17(0.90); C26(1.09)  LDD0560  [14]
 LDCM0244  AC126 HCT 116 C17(1.00); C26(1.31)  LDD0561  [14]
 LDCM0245  AC127 HCT 116 C17(0.89); C26(1.48)  LDD0562  [14]
 LDCM0246  AC128 HCT 116 C17(1.06); C26(1.29)  LDD0563  [14]
 LDCM0247  AC129 HCT 116 C17(0.80); C26(0.99)  LDD0564  [14]
 LDCM0249  AC130 HCT 116 C17(1.16); C26(1.42)  LDD0566  [14]
 LDCM0250  AC131 HCT 116 C17(0.77); C26(0.94)  LDD0567  [14]
 LDCM0251  AC132 HCT 116 C17(0.81); C26(0.97)  LDD0568  [14]
 LDCM0252  AC133 HCT 116 C17(0.87); C26(0.95)  LDD0569  [14]
 LDCM0253  AC134 HCT 116 C17(1.03); C26(1.33)  LDD0570  [14]
 LDCM0254  AC135 HCT 116 C17(0.92); C26(1.26)  LDD0571  [14]
 LDCM0255  AC136 HCT 116 C17(0.93); C26(0.98)  LDD0572  [14]
 LDCM0256  AC137 HCT 116 C17(0.88); C26(0.95)  LDD0573  [14]
 LDCM0257  AC138 HCT 116 C17(1.13); C26(1.31)  LDD0574  [14]
 LDCM0258  AC139 HCT 116 C17(1.00); C26(1.26)  LDD0575  [14]
 LDCM0259  AC14 HCT 116 C17(1.28); C26(1.15)  LDD0576  [14]
 LDCM0260  AC140 HCT 116 C17(0.99); C26(1.23)  LDD0577  [14]
 LDCM0261  AC141 HCT 116 C17(0.98); C26(1.25)  LDD0578  [14]
 LDCM0262  AC142 HCT 116 C17(0.86); C26(0.95)  LDD0579  [14]
 LDCM0263  AC143 HCT 116 C17(1.10); C26(1.18)  LDD0580  [14]
 LDCM0264  AC144 HCT 116 C17(1.14); C26(1.39)  LDD0581  [14]
 LDCM0265  AC145 HCT 116 C17(1.03); C26(1.20)  LDD0582  [14]
 LDCM0266  AC146 HCT 116 C17(1.84); C26(1.85)  LDD0583  [14]
 LDCM0267  AC147 HCT 116 C17(1.23); C26(1.28)  LDD0584  [14]
 LDCM0268  AC148 HCT 116 C17(1.60); C26(1.93)  LDD0585  [14]
 LDCM0269  AC149 HCT 116 C17(1.50); C26(1.61)  LDD0586  [14]
 LDCM0270  AC15 HCT 116 C26(1.09); C17(1.11)  LDD0587  [14]
 LDCM0271  AC150 HCT 116 C17(1.17); C26(1.25)  LDD0588  [14]
 LDCM0272  AC151 HCT 116 C17(1.15); C26(1.32)  LDD0589  [14]
 LDCM0273  AC152 HCT 116 C26(1.45); C17(1.52)  LDD0590  [14]
 LDCM0274  AC153 HCT 116 C17(1.63); C26(1.76)  LDD0591  [14]
 LDCM0621  AC154 HCT 116 C17(1.25); C26(1.47)  LDD2158  [14]
 LDCM0622  AC155 HCT 116 C17(1.60); C26(1.59)  LDD2159  [14]
 LDCM0623  AC156 HCT 116 C17(1.14); C26(1.09)  LDD2160  [14]
 LDCM0624  AC157 HCT 116 C17(1.20); C26(1.16)  LDD2161  [14]
 LDCM0276  AC17 HCT 116 C17(1.13); C26(1.23)  LDD0593  [14]
 LDCM0277  AC18 HCT 116 C26(1.80); C17(1.96)  LDD0594  [14]
 LDCM0278  AC19 HCT 116 C26(1.45); C17(1.55)  LDD0595  [14]
 LDCM0279  AC2 HCT 116 C26(1.36); C17(1.77)  LDD0596  [14]
 LDCM0280  AC20 HCT 116 C17(1.21); C26(1.24)  LDD0597  [14]
 LDCM0281  AC21 HCT 116 C26(1.32); C17(1.38)  LDD0598  [14]
 LDCM0282  AC22 HCT 116 C17(1.09); C26(1.17)  LDD0599  [14]
 LDCM0283  AC23 HCT 116 C26(1.40); C17(1.44)  LDD0600  [14]
 LDCM0284  AC24 HCT 116 C17(0.99); C26(1.08)  LDD0601  [14]
 LDCM0285  AC25 HCT 116 C26(1.25); C17(1.29)  LDD0602  [14]
 LDCM0286  AC26 HCT 116 C26(1.53); C17(1.54)  LDD0603  [14]
 LDCM0287  AC27 HCT 116 C26(1.58); C17(1.60)  LDD0604  [14]
 LDCM0288  AC28 HCT 116 C26(1.57); C17(1.66)  LDD0605  [14]
 LDCM0289  AC29 HCT 116 C17(1.66); C26(1.75)  LDD0606  [14]
 LDCM0290  AC3 HCT 116 C26(1.07); C17(1.08)  LDD0607  [14]
 LDCM0291  AC30 HCT 116 C26(1.69); C17(1.84)  LDD0608  [14]
 LDCM0292  AC31 HCT 116 C17(1.35); C26(1.46)  LDD0609  [14]
 LDCM0293  AC32 HCT 116 C26(1.89); C17(1.94)  LDD0610  [14]
 LDCM0294  AC33 HCT 116 C17(1.66); C26(1.68)  LDD0611  [14]
 LDCM0295  AC34 HCT 116 C26(1.87); C17(1.96)  LDD0612  [14]
 LDCM0296  AC35 HCT 116 C26(0.83); C17(0.85)  LDD0613  [14]
 LDCM0297  AC36 HCT 116 C17(0.91); C26(0.91)  LDD0614  [14]
 LDCM0298  AC37 HCT 116 C26(0.85); C17(0.94)  LDD0615  [14]
 LDCM0299  AC38 HCT 116 C17(0.96); C26(0.97)  LDD0616  [14]
 LDCM0300  AC39 HCT 116 C17(1.07); C26(1.12)  LDD0617  [14]
 LDCM0301  AC4 HCT 116 C17(1.30); C26(1.49)  LDD0618  [14]
 LDCM0302  AC40 HCT 116 C17(1.08); C26(1.26)  LDD0619  [14]
 LDCM0303  AC41 HCT 116 C17(1.11); C26(1.12)  LDD0620  [14]
 LDCM0304  AC42 HCT 116 C17(1.09); C26(1.19)  LDD0621  [14]
 LDCM0305  AC43 HCT 116 C26(1.20); C17(1.25)  LDD0622  [14]
 LDCM0306  AC44 HCT 116 C17(0.99); C26(1.12)  LDD0623  [14]
 LDCM0307  AC45 HCT 116 C17(1.30); C26(1.32)  LDD0624  [14]
 LDCM0308  AC46 HCT 116 C26(1.03); C17(1.17)  LDD0625  [14]
 LDCM0309  AC47 HCT 116 C26(1.07); C17(1.13)  LDD0626  [14]
 LDCM0310  AC48 HCT 116 C26(1.05); C17(1.17)  LDD0627  [14]
 LDCM0311  AC49 HCT 116 C17(1.60); C26(1.61)  LDD0628  [14]
 LDCM0312  AC5 HCT 116 C17(1.38); C26(1.52)  LDD0629  [14]
 LDCM0313  AC50 HCT 116 C26(1.60); C17(1.78)  LDD0630  [14]
 LDCM0314  AC51 HCT 116 C26(0.93); C17(0.99)  LDD0631  [14]
 LDCM0315  AC52 HCT 116 C26(1.10); C17(1.19)  LDD0632  [14]
 LDCM0316  AC53 HCT 116 C26(1.37); C17(1.39)  LDD0633  [14]
 LDCM0317  AC54 HCT 116 C26(1.19); C17(1.26)  LDD0634  [14]
 LDCM0318  AC55 HCT 116 C17(1.54); C26(1.58)  LDD0635  [14]
 LDCM0319  AC56 HCT 116 C26(2.01); C17(2.09)  LDD0636  [14]
 LDCM0320  AC57 HCT 116 C17(1.67); C26(1.78)  LDD0637  [14]
 LDCM0321  AC58 HCT 116 C17(1.40); C26(1.62)  LDD0638  [14]
 LDCM0322  AC59 HCT 116 C17(1.50); C26(1.83)  LDD0639  [14]
 LDCM0323  AC6 HCT 116 C26(1.31); C17(1.36)  LDD0640  [14]
 LDCM0324  AC60 HCT 116 C17(1.54); C26(1.72)  LDD0641  [14]
 LDCM0325  AC61 HCT 116 C17(1.21); C26(1.34)  LDD0642  [14]
 LDCM0326  AC62 HCT 116 C17(1.62); C26(1.63)  LDD0643  [14]
 LDCM0327  AC63 HCT 116 C17(1.39); C26(1.69)  LDD0644  [14]
 LDCM0328  AC64 HCT 116 C17(1.41); C26(1.72)  LDD0645  [14]
 LDCM0329  AC65 HCT 116 C17(1.00); C26(1.15)  LDD0646  [14]
 LDCM0330  AC66 HCT 116 C17(0.99); C26(1.16)  LDD0647  [14]
 LDCM0331  AC67 HCT 116 C17(1.19); C26(1.38)  LDD0648  [14]
 LDCM0332  AC68 HCT 116 C17(1.15); C26(1.23)  LDD0649  [14]
 LDCM0333  AC69 HCT 116 C17(1.11); C26(1.41)  LDD0650  [14]
 LDCM0334  AC7 HCT 116 C26(1.06); C17(1.06)  LDD0651  [14]
 LDCM0335  AC70 HCT 116 C17(1.28); C26(1.42)  LDD0652  [14]
 LDCM0336  AC71 HCT 116 C17(0.89); C26(1.19)  LDD0653  [14]
 LDCM0337  AC72 HCT 116 C17(1.18); C26(1.35)  LDD0654  [14]
 LDCM0338  AC73 HCT 116 C17(1.64); C26(1.95)  LDD0655  [14]
 LDCM0339  AC74 HCT 116 C17(1.25); C26(1.80)  LDD0656  [14]
 LDCM0340  AC75 HCT 116 C17(1.92); C26(2.62)  LDD0657  [14]
 LDCM0341  AC76 HCT 116 C17(1.26); C26(1.36)  LDD0658  [14]
 LDCM0342  AC77 HCT 116 C17(1.45); C26(1.49)  LDD0659  [14]
 LDCM0343  AC78 HCT 116 C17(1.14); C26(1.33)  LDD0660  [14]
 LDCM0344  AC79 HCT 116 C17(1.17); C26(1.36)  LDD0661  [14]
 LDCM0345  AC8 HCT 116 C17(1.07); C26(1.14)  LDD0662  [14]
 LDCM0346  AC80 HCT 116 C17(1.18); C26(1.35)  LDD0663  [14]
 LDCM0347  AC81 HCT 116 C17(1.09); C26(1.24)  LDD0664  [14]
 LDCM0348  AC82 HCT 116 C17(1.49); C26(1.92)  LDD0665  [14]
 LDCM0349  AC83 HCT 116 C17(1.46); C26(1.90)  LDD0666  [14]
 LDCM0350  AC84 HCT 116 C17(1.28); C26(1.40)  LDD0667  [14]
 LDCM0351  AC85 HCT 116 C17(1.31); C26(1.39)  LDD0668  [14]
 LDCM0352  AC86 HCT 116 C17(1.36); C26(1.42)  LDD0669  [14]
 LDCM0353  AC87 HCT 116 C26(1.08); C17(1.25)  LDD0670  [14]
 LDCM0354  AC88 HCT 116 C26(1.33); C17(1.34)  LDD0671  [14]
 LDCM0355  AC89 HCT 116 C26(1.40); C17(1.50)  LDD0672  [14]
 LDCM0357  AC90 HCT 116 C26(1.05); C17(1.19)  LDD0674  [14]
 LDCM0358  AC91 HCT 116 C17(1.54); C26(1.91)  LDD0675  [14]
 LDCM0359  AC92 HCT 116 C17(1.39); C26(1.61)  LDD0676  [14]
 LDCM0360  AC93 HCT 116 C26(1.17); C17(1.22)  LDD0677  [14]
 LDCM0361  AC94 HCT 116 C17(1.11); C26(1.12)  LDD0678  [14]
 LDCM0362  AC95 HCT 116 C17(1.25); C26(1.34)  LDD0679  [14]
 LDCM0363  AC96 HCT 116 C26(1.40); C17(1.55)  LDD0680  [14]
 LDCM0364  AC97 HCT 116 C17(1.57); C26(1.66)  LDD0681  [14]
 LDCM0365  AC98 HCT 116 C26(1.51); C17(1.52)  LDD0682  [14]
 LDCM0366  AC99 HCT 116 C26(1.06); C17(1.09)  LDD0683  [14]
 LDCM0520  AKOS000195272 MDA-MB-231 C26(0.79); C17(0.90)  LDD2113  [11]
 LDCM0248  AKOS034007472 HCT 116 C17(1.02); C26(0.96)  LDD0565  [14]
 LDCM0356  AKOS034007680 HCT 116 C17(1.32); C26(1.35)  LDD0673  [14]
 LDCM0275  AKOS034007705 HCT 116 C17(1.69); C26(1.85)  LDD0592  [14]
 LDCM0156  Aniline NCI-H1299 11.93  LDD0403  [1]
 LDCM0088  C45 HEK-293T 19.96  LDD0202  [9]
 LDCM0087  Capsaicin HEK-293T 6.38  LDD0185  [3]
 LDCM0108  Chloroacetamide HeLa H216(0.00); H199(0.00); H144(0.00); C26(0.00)  LDD0222  [24]
 LDCM0632  CL-Sc Hep-G2 C17(0.66)  LDD2227  [19]
 LDCM0367  CL1 HCT 116 C26(0.89); C17(1.04)  LDD0684  [14]
 LDCM0368  CL10 HCT 116 C17(1.65); C26(1.70)  LDD0685  [14]
 LDCM0369  CL100 HCT 116 C26(1.39); C17(1.59)  LDD0686  [14]
 LDCM0370  CL101 HCT 116 C26(1.47); C17(1.51)  LDD0687  [14]
 LDCM0371  CL102 HCT 116 C26(1.12); C17(1.17)  LDD0688  [14]
 LDCM0372  CL103 HCT 116 C26(1.11); C17(1.17)  LDD0689  [14]
 LDCM0373  CL104 HCT 116 C26(1.09); C17(1.15)  LDD0690  [14]
 LDCM0374  CL105 HCT 116 C26(1.61); C17(1.73)  LDD0691  [14]
 LDCM0375  CL106 HCT 116 C26(2.28); C17(2.37)  LDD0692  [14]
 LDCM0376  CL107 HCT 116 C17(1.74); C26(1.91)  LDD0693  [14]
 LDCM0377  CL108 HCT 116 C17(1.72); C26(1.81)  LDD0694  [14]
 LDCM0378  CL109 HCT 116 C26(1.45); C17(1.46)  LDD0695  [14]
 LDCM0379  CL11 HCT 116 C26(1.57); C17(1.68)  LDD0696  [14]
 LDCM0380  CL110 HCT 116 C26(1.81); C17(2.02)  LDD0697  [14]
 LDCM0381  CL111 HCT 116 C26(1.49); C17(1.49)  LDD0698  [14]
 LDCM0382  CL112 HCT 116 C26(1.43); C17(1.44)  LDD0699  [14]
 LDCM0383  CL113 HCT 116 C26(1.60); C17(1.70)  LDD0700  [14]
 LDCM0384  CL114 HCT 116 C26(1.90); C17(1.94)  LDD0701  [14]
 LDCM0385  CL115 HCT 116 C26(1.64); C17(1.70)  LDD0702  [14]
 LDCM0386  CL116 HCT 116 C17(1.48); C26(1.53)  LDD0703  [14]
 LDCM0387  CL117 HCT 116 C17(1.65); C26(1.82)  LDD0704  [14]
 LDCM0388  CL118 HCT 116 C17(1.04); C26(1.12)  LDD0705  [14]
 LDCM0389  CL119 HCT 116 C26(1.13); C17(1.29)  LDD0706  [14]
 LDCM0390  CL12 HCT 116 C17(1.31); C26(1.90)  LDD0707  [14]
 LDCM0391  CL120 HCT 116 C17(1.01); C26(1.01)  LDD0708  [14]
 LDCM0392  CL121 HCT 116 C26(1.53); C17(2.47)  LDD0709  [14]
 LDCM0393  CL122 HCT 116 C26(1.13); C17(1.18)  LDD0710  [14]
 LDCM0394  CL123 HCT 116 C26(1.45); C17(1.63)  LDD0711  [14]
 LDCM0395  CL124 HCT 116 C26(1.67); C17(1.79)  LDD0712  [14]
 LDCM0396  CL125 HCT 116 C17(1.01); C26(1.10)  LDD0713  [14]
 LDCM0397  CL126 HCT 116 C26(1.10); C17(1.13)  LDD0714  [14]
 LDCM0398  CL127 HCT 116 C17(0.98); C26(1.05)  LDD0715  [14]
 LDCM0399  CL128 HCT 116 C17(1.48); C26(1.75)  LDD0716  [14]
 LDCM0400  CL13 HCT 116 C17(0.99); C26(1.22)  LDD0717  [14]
 LDCM0401  CL14 HCT 116 C17(0.80); C26(0.98)  LDD0718  [14]
 LDCM0402  CL15 HCT 116 C17(0.90); C26(1.18)  LDD0719  [14]
 LDCM0403  CL16 HCT 116 C26(1.15); C17(1.38)  LDD0720  [14]
 LDCM0404  CL17 HCT 116 C26(1.47); C17(1.68)  LDD0721  [14]
 LDCM0405  CL18 HCT 116 C26(1.29); C17(1.37)  LDD0722  [14]
 LDCM0406  CL19 HCT 116 C26(1.25); C17(1.40)  LDD0723  [14]
 LDCM0407  CL2 HCT 116 C26(0.85); C17(0.91)  LDD0724  [14]
 LDCM0408  CL20 HCT 116 C26(1.70); C17(1.76)  LDD0725  [14]
 LDCM0409  CL21 HCT 116 C26(2.11); C17(2.20)  LDD0726  [14]
 LDCM0410  CL22 HCT 116 C17(2.29); C26(2.65)  LDD0727  [14]
 LDCM0411  CL23 HCT 116 C26(1.50); C17(1.61)  LDD0728  [14]
 LDCM0412  CL24 HCT 116 C17(1.81); C26(1.72)  LDD0729  [14]
 LDCM0413  CL25 HCT 116 C17(2.14); C26(1.95)  LDD0730  [14]
 LDCM0414  CL26 HCT 116 C17(1.48); C26(1.42)  LDD0731  [14]
 LDCM0415  CL27 HCT 116 C17(1.94); C26(1.61)  LDD0732  [14]
 LDCM0416  CL28 HCT 116 C17(1.49); C26(1.36)  LDD0733  [14]
 LDCM0417  CL29 HCT 116 C17(1.69); C26(1.62)  LDD0734  [14]
 LDCM0418  CL3 HCT 116 C17(1.28); C26(1.01)  LDD0735  [14]
 LDCM0419  CL30 HCT 116 C17(1.28); C26(1.23)  LDD0736  [14]
 LDCM0420  CL31 HCT 116 C17(1.37); C26(1.32)  LDD0737  [14]
 LDCM0421  CL32 HCT 116 C17(1.45); C26(1.42)  LDD0738  [14]
 LDCM0422  CL33 HCT 116 C17(2.02); C26(1.73)  LDD0739  [14]
 LDCM0423  CL34 HCT 116 C17(2.19); C26(1.96)  LDD0740  [14]
 LDCM0424  CL35 HCT 116 C17(2.31); C26(2.06)  LDD0741  [14]
 LDCM0425  CL36 HCT 116 C17(1.97); C26(1.81)  LDD0742  [14]
 LDCM0426  CL37 HCT 116 C17(2.55); C26(2.47)  LDD0743  [14]
 LDCM0428  CL39 HCT 116 C17(2.09); C26(2.06)  LDD0745  [14]
 LDCM0429  CL4 HCT 116 C17(0.63); C26(0.79)  LDD0746  [14]
 LDCM0430  CL40 HCT 116 C17(2.20); C26(1.88)  LDD0747  [14]
 LDCM0431  CL41 HCT 116 C17(1.75); C26(1.84)  LDD0748  [14]
 LDCM0432  CL42 HCT 116 C17(3.55); C26(3.81)  LDD0749  [14]
 LDCM0433  CL43 HCT 116 C17(2.54); C26(2.36)  LDD0750  [14]
 LDCM0434  CL44 HCT 116 C17(1.93); C26(1.88)  LDD0751  [14]
 LDCM0435  CL45 HCT 116 C17(2.67); C26(2.36)  LDD0752  [14]
 LDCM0436  CL46 HCT 116 C17(0.84); C26(0.90)  LDD0753  [14]
 LDCM0437  CL47 HCT 116 C17(0.84); C26(0.90)  LDD0754  [14]
 LDCM0438  CL48 HCT 116 C17(0.87); C26(0.98)  LDD0755  [14]
 LDCM0439  CL49 HCT 116 C17(0.95); C26(1.00)  LDD0756  [14]
 LDCM0440  CL5 HCT 116 C17(1.02); C26(0.95)  LDD0757  [14]
 LDCM0441  CL50 HCT 116 C17(0.97); C26(0.95)  LDD0758  [14]
 LDCM0442  CL51 HCT 116 C17(0.99); C26(1.06)  LDD0759  [14]
 LDCM0443  CL52 HCT 116 C17(1.01); C26(1.09)  LDD0760  [14]
 LDCM0444  CL53 HCT 116 C17(0.89); C26(0.92)  LDD0761  [14]
 LDCM0445  CL54 HCT 116 C17(0.94); C26(0.99)  LDD0762  [14]
 LDCM0446  CL55 HCT 116 C17(0.93); C26(0.99)  LDD0763  [14]
 LDCM0447  CL56 HCT 116 C17(0.98); C26(1.05)  LDD0764  [14]
 LDCM0448  CL57 HCT 116 C17(0.85); C26(0.84)  LDD0765  [14]
 LDCM0449  CL58 HCT 116 C17(0.76); C26(0.84)  LDD0766  [14]
 LDCM0450  CL59 HCT 116 C17(0.94); C26(1.01)  LDD0767  [14]
 LDCM0451  CL6 HCT 116 C17(1.17); C26(1.22)  LDD0768  [14]
 LDCM0452  CL60 HCT 116 C17(0.88); C26(0.95)  LDD0769  [14]
 LDCM0453  CL61 HCT 116 C17(1.23); C26(1.31)  LDD0770  [14]
 LDCM0454  CL62 HCT 116 C17(1.20); C26(1.37)  LDD0771  [14]
 LDCM0455  CL63 HCT 116 C17(1.72); C26(1.82)  LDD0772  [14]
 LDCM0456  CL64 HCT 116 C17(2.34); C26(2.01)  LDD0773  [14]
 LDCM0457  CL65 HCT 116 C17(1.17); C26(1.32)  LDD0774  [14]
 LDCM0458  CL66 HCT 116 C17(1.91); C26(2.44)  LDD0775  [14]
 LDCM0459  CL67 HCT 116 C17(1.59); C26(1.60)  LDD0776  [14]
 LDCM0460  CL68 HCT 116 C17(1.64); C26(1.64)  LDD0777  [14]
 LDCM0461  CL69 HCT 116 C17(1.50); C26(1.51)  LDD0778  [14]
 LDCM0462  CL7 HCT 116 C17(1.28); C26(1.43)  LDD0779  [14]
 LDCM0463  CL70 HCT 116 C17(1.47); C26(1.60)  LDD0780  [14]
 LDCM0464  CL71 HCT 116 C17(1.80); C26(1.83)  LDD0781  [14]
 LDCM0465  CL72 HCT 116 C17(1.23); C26(1.25)  LDD0782  [14]
 LDCM0466  CL73 HCT 116 C17(1.71); C26(1.75)  LDD0783  [14]
 LDCM0467  CL74 HCT 116 C17(1.74); C26(1.74)  LDD0784  [14]
 LDCM0469  CL76 HCT 116 C17(1.44); C26(1.46)  LDD0786  [14]
 LDCM0470  CL77 HCT 116 C17(1.30); C26(1.44)  LDD0787  [14]
 LDCM0471  CL78 HCT 116 C17(1.61); C26(1.59)  LDD0788  [14]
 LDCM0472  CL79 HCT 116 C17(1.92); C26(2.02)  LDD0789  [14]
 LDCM0473  CL8 HCT 116 C17(3.10); C26(2.42)  LDD0790  [14]
 LDCM0474  CL80 HCT 116 C17(1.18); C26(1.24)  LDD0791  [14]
 LDCM0475  CL81 HCT 116 C17(1.38); C26(1.45)  LDD0792  [14]
 LDCM0476  CL82 HCT 116 C17(3.29); C26(3.38)  LDD0793  [14]
 LDCM0477  CL83 HCT 116 C17(2.11); C26(2.21)  LDD0794  [14]
 LDCM0478  CL84 HCT 116 C17(3.06); C26(3.05)  LDD0795  [14]
 LDCM0479  CL85 HCT 116 C17(1.45); C26(1.47)  LDD0796  [14]
 LDCM0480  CL86 HCT 116 C17(1.09); C26(1.15)  LDD0797  [14]
 LDCM0481  CL87 HCT 116 C17(1.43); C26(1.45)  LDD0798  [14]
 LDCM0482  CL88 HCT 116 C17(2.25); C26(2.12)  LDD0799  [14]
 LDCM0483  CL89 HCT 116 C17(3.55); C26(3.53)  LDD0800  [14]
 LDCM0484  CL9 HCT 116 C17(1.17); C26(1.41)  LDD0801  [14]
 LDCM0485  CL90 HCT 116 C17(1.01); C26(1.10)  LDD0802  [14]
 LDCM0486  CL91 HCT 116 C17(1.53); C26(1.41)  LDD0803  [14]
 LDCM0487  CL92 HCT 116 C17(1.46); C26(1.24)  LDD0804  [14]
 LDCM0488  CL93 HCT 116 C17(1.42); C26(1.14)  LDD0805  [14]
 LDCM0489  CL94 HCT 116 C17(1.63); C26(1.67)  LDD0806  [14]
 LDCM0490  CL95 HCT 116 C17(1.30); C26(1.71)  LDD0807  [14]
 LDCM0491  CL96 HCT 116 C17(1.22); C26(1.15)  LDD0808  [14]
 LDCM0492  CL97 HCT 116 C17(1.89); C26(1.42)  LDD0809  [14]
 LDCM0493  CL98 HCT 116 C17(1.27); C26(1.31)  LDD0810  [14]
 LDCM0494  CL99 HCT 116 C17(1.20); C26(1.22)  LDD0811  [14]
 LDCM0017  DFG-out-2 A431 4.80  LDD0075  [31]
 LDCM0028  Dobutamine HEK-293T 5.11  LDD0180  [3]
 LDCM0027  Dopamine HEK-293T 6.88  LDD0179  [3]
 LDCM0495  E2913 HEK-293T C26(0.96); C17(1.04)  LDD1698  [33]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C17(2.72); C26(1.98)  LDD1702  [11]
 LDCM0031  Epigallocatechin gallate HEK-293T 5.24  LDD0183  [3]
 LDCM0625  F8 Ramos 0.56; C17(1.85)  LDD2187  [34]
 LDCM0572  Fragment10 Ramos 2.89; C17(2.48)  LDD2189  [34]
 LDCM0573  Fragment11 Ramos 1.30; C17(2.24)  LDD2190  [34]
 LDCM0574  Fragment12 Ramos 1.92; C17(1.66)  LDD2191  [34]
 LDCM0575  Fragment13 Ramos 0.96; C17(0.85)  LDD2192  [34]
 LDCM0576  Fragment14 Ramos 0.30; C17(1.67)  LDD2193  [34]
 LDCM0579  Fragment20 Ramos 1.48; C17(1.14)  LDD2194  [34]
 LDCM0580  Fragment21 Ramos 0.66; C17(0.96)  LDD2195  [34]
 LDCM0582  Fragment23 Ramos 1.34; C17(0.56)  LDD2196  [34]
 LDCM0578  Fragment27 Ramos 0.87; C17(1.29)  LDD2197  [34]
 LDCM0586  Fragment28 Ramos 0.95; C17(0.81)  LDD2198  [34]
 LDCM0588  Fragment30 Ramos 1.64; C17(1.65)  LDD2199  [34]
 LDCM0589  Fragment31 Ramos 1.26; C17(0.72)  LDD2200  [34]
 LDCM0590  Fragment32 Ramos 2.81; C17(1.65)  LDD2201  [34]
 LDCM0468  Fragment33 HCT 116 C17(1.82); C26(1.51)  LDD0785  [14]
 LDCM0596  Fragment38 Ramos 1.06; C17(0.38)  LDD2203  [34]
 LDCM0566  Fragment4 Ramos 1.09; C17(0.78)  LDD2184  [34]
 LDCM0427  Fragment51 HCT 116 C17(4.03); C26(3.40)  LDD0744  [14]
 LDCM0610  Fragment52 Ramos 2.69; C17(3.12)  LDD2204  [34]
 LDCM0614  Fragment56 Ramos 2.22; C17(1.33)  LDD2205  [34]
 LDCM0569  Fragment7 Ramos C17(1.17)  LDD2186  [34]
 LDCM0571  Fragment9 Ramos 2.83; C17(3.35)  LDD2188  [34]
 LDCM0107  IAA HeLa H144(0.00); H199(0.00); H216(0.00)  LDD0221  [24]
 LDCM0179  JZ128 PC-3 C26(0.00); C17(0.00)  LDD0462  [10]
 LDCM0022  KB02 HCT 116 C17(5.30); C26(1.35)  LDD0080  [14]
 LDCM0023  KB03 HCT 116 C17(3.96); C26(1.50)  LDD0081  [14]
 LDCM0024  KB05 HCT 116 C17(15.88); C26(1.47)  LDD0082  [14]
 LDCM0030  Luteolin HEK-293T 14.25  LDD0182  [3]
 LDCM0109  NEM HeLa H216(0.00); H144(0.00); H199(0.00)  LDD0223  [24]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C26(1.22)  LDD2090  [11]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C17(1.41)  LDD2094  [11]
 LDCM0504  Nucleophilic fragment 15a MDA-MB-231 C26(1.22)  LDD2097  [11]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C26(0.75)  LDD2099  [11]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C26(0.47)  LDD2100  [11]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C26(0.88); C17(0.94)  LDD2101  [11]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C26(0.36)  LDD2104  [11]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C17(1.30)  LDD2105  [11]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C26(0.84)  LDD2107  [11]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C26(0.47)  LDD2108  [11]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C26(1.06); C17(0.85)  LDD2109  [11]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C26(0.78)  LDD2111  [11]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C26(0.58); C17(0.63)  LDD2115  [11]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C26(0.65); C17(0.57)  LDD2123  [11]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C26(0.59); C17(0.61)  LDD2125  [11]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C26(0.70); C17(0.74)  LDD2127  [11]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C26(0.74)  LDD2129  [11]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C26(0.69); C17(0.77)  LDD2133  [11]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C26(0.72); C17(0.84)  LDD2134  [11]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C26(0.70)  LDD2135  [11]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C26(0.99); C17(1.14)  LDD2136  [11]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C26(0.98); C17(1.03)  LDD2137  [11]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C26(1.05)  LDD1700  [11]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C26(0.70)  LDD2140  [11]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C26(0.68); C17(0.81)  LDD2141  [11]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C26(1.01)  LDD2145  [11]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C26(0.91)  LDD2146  [11]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C26(0.56); C17(0.66)  LDD2148  [11]
 LDCM0559  Nucleophilic fragment 9b MDA-MB-231 C26(1.84)  LDD2153  [11]
 LDCM0627  NUDT7-COV-1 HEK-293T C17(0.64)  LDD2206  [35]
 LDCM0032  Oleacein HEK-293T 4.80  LDD0184  [3]
 LDCM0628  OTUB2-COV-1 HEK-293T C17(0.68)  LDD2207  [35]
 LDCM0029  Quercetin HEK-293T 9.25  LDD0181  [3]
 LDCM0131  RA190 MM1.R C17(2.05); C26(2.05)  LDD0304  [36]
 LDCM0003  Sulforaphane MCF-7 2.94  LDD0042  [12]
 LDCM0112  W16 Hep-G2 C26(0.75); C17(0.79)  LDD0239  [6]

References

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Mass spectrometry data entry: PXD043348
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Mass spectrometry data entry: PXD018580
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Mass spectrometry data entry: PXD028270
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Mass spectrometry data entry: PXD039908 , PXD029761
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Mass spectrometry data entry: PXD006279
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Mass spectrometry data entry: PXD044625
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Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
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Mass spectrometry data entry: PXD006095 , PXD006096
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Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD029255
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Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD041587
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Mass spectrometry data entry: PXD007570
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