Details of the Probe

General Information of Probe

Probe ID
LDPC0624
Probe Name
C407
Synonyms
Z4282859685
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 391.5
Lipid-water partition coefficient (xlogp) 4
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C24H29N3O2
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-N-[4-(3-hydroxy-1-adamantyl)phenyl]propanamide
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)NC2=CC=C(C=C2)C34CC5CC(C3)CC(C5)(C4)O
InChI
InChI=1S/C24H29N3O2/c1-2-3-9-24(26-27-24)10-8-21(28)25-20-6-4-19(5-7-20)22-12-17-11-18(13-22)15-23(29,14-17)16-22/h1,4-7,17-18,29H,3,8-16H2,(H,25,28)
InChIKey
YUAVWCUZHJAIBX-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

150 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (BCKDHA) LDTP02627 13.36  LDD2064 
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (HIBCH) LDTP07483 15.45  LDD2064 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 15.03  LDD2064 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 15.03  LDD2064 
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 (LPGAT1) LDTP09814 10.85  LDD2064 
Acyl-coenzyme A thioesterase 1 (ACOT1) LDTP08209 34.30  LDD2064 
Adenosine deaminase (ADA) LDTP01803 13.83  LDD2064 
Adenosine kinase (ADK) LDTP04689 26.54  LDD2064 
ADP-dependent glucokinase (ADPGK) LDTP11127 24.25  LDD2064 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 37.01  LDD2064 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 10.93  LDD2064 
Atlastin-2 (ATL2) LDTP09251 17.27  LDD2064 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 19.70  LDD2064 
ATP-binding cassette sub-family D member 1 (ABCD1) LDTP03676 15.24  LDD2064 
ATPase family AAA domain-containing protein 3A (ATAD3A) LDTP12681 12.04  LDD2064 
ATPase GET3 (GET3) LDTP00836 11.31  LDD2064 
Atypical kinase COQ8A, mitochondrial (COQ8A) LDTP09285 16.00  LDD2064 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 13.36  LDD2064 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 14.62  LDD2064 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 22.78  LDD2064 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 30.27  LDD2064 
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) LDTP04358 15.03  LDD2064 
Catechol O-methyltransferase (COMT) LDTP03145 16.11  LDD2064 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 25.81  LDD2064 
Ceramide glucosyltransferase (UGCG) LDTP06617 39.67  LDD2064 
Ceramide synthase 1 (CERS1) LDTP03394 14.72  LDD2064 
Ceramide synthase 2 (CERS2) LDTP10329 23.43  LDD2064 
Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) LDTP11178 16.00  LDD2064 
Choline dehydrogenase, mitochondrial (CHDH) LDTP15505 15.78  LDD2064 
Cytochrome b-c1 complex subunit 2, mitochondrial (UQCRC2) LDTP03189 16.68  LDD2064 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 40.79  LDD2064 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 54.95  LDD2064 
Cytochrome b5 type B (CYB5B) LDTP00697 36.00  LDD2064 
Cytochrome c oxidase assembly factor 7 (COA7) LDTP10137 13.27  LDD2064 
Cytochrome c oxidase subunit 2 (MT-CO2) LDTP01773 18.25  LDD2064 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 28.64  LDD2064 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 14.62  LDD2064 
Delta(24)-sterol reductase (DHCR24) LDTP06375 13.64  LDD2064 
Deoxyhypusine synthase (DHPS) LDTP04248 13.55  LDD2064 
Dephospho-CoA kinase domain-containing protein (DCAKD) LDTP18087 17.88  LDD2064 
DGAT1/2-independent enzyme synthesizing storage lipids (TMEM68) LDTP19892 23.10  LDD2064 
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM17) LDTP05137 15.03  LDD2064 
DNA replication licensing factor MCM2 (MCM2) LDTP04286 11.63  LDD2064 
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase (ALG6) LDTP14213 12.64  LDD2064 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) LDTP04120 17.15  LDD2064 
Dynamin-like 120 kDa protein, mitochondrial (OPA1) LDTP00950 12.73  LDD2064 
E3 ubiquitin-protein ligase TRIM13 (TRIM13) LDTP01065 38.85  LDD2064 
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (ETFDH) LDTP06511 13.36  LDD2064 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 13.83  LDD2064 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 11.47  LDD2064 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 22.78  LDD2064 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 19.29  LDD2064 
Epoxide hydrolase 1 (EPHX1) LDTP02175 21.41  LDD2064 
Exostosin-like 3 (EXTL3) LDTP00899 11.24  LDD2064 
Ferrochelatase, mitochondrial (FECH) LDTP03198 13.74  LDD2064 
Geranylgeranyl transferase type-2 subunit beta (RABGGTB) LDTP04569 13.36  LDD2064 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 22.16  LDD2064 
Heme oxygenase 1 (HMOX1) LDTP02359 35.51  LDD2064 
Heme oxygenase 2 (HMOX2) LDTP03540 42.81  LDD2064 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 22.47  LDD2064 
Hexokinase-2 (HK2) LDTP04531 13.74  LDD2064 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 15.35  LDD2064 
Holocytochrome c-type synthase (HCCS) LDTP04581 11.08  LDD2064 
Hydroxysteroid dehydrogenase-like protein 2 (HSDL2) LDTP07762 11.96  LDD2064 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 41.07  LDD2064 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 20.11  LDD2064 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 17.75  LDD2064 
Lipid droplet-associated hydrolase (LDAH) LDTP16007 24.08  LDD2064 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 13.00  LDD2064 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 10.93  LDD2064 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 18.77  LDD2064 
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) LDTP10930 19.56  LDD2064 
Methionine aminopeptidase 1 (METAP1) LDTP04565 11.88  LDD2064 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 21.41  LDD2064 
Microsomal glutathione S-transferase 2 (MGST2) LDTP10966 12.13  LDD2064 
Mitochondrial intermediate peptidase (MIPEP) LDTP10981 16.68  LDD2064 
Mitofusin-1 (MFN1) LDTP08530 15.89  LDD2064 
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase (PIGL) LDTP16258 14.52  LDD2064 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 13.09  LDD2064 
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) LDTP08598 13.00  LDD2064 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 38.85  LDD2064 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 34.54  LDD2064 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 58.89  LDD2064 
NADH dehydrogenase 1 beta subcomplex subunit 9 (NDUFB9) LDTP14276 18.77  LDD2064 
NADH dehydrogenase 1 subunit C2 (NDUFC2) LDTP01560 13.93  LDD2064 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 21.56  LDD2064 
NADPH--cytochrome P450 reductase (POR) LDTP02848 11.00  LDD2064 
Nardilysin (NRDC) LDTP00886 11.55  LDD2064 
Obg-like ATPase 1 (OLA1) LDTP12610 21.71  LDD2064 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 18.00  LDD2064 
Palmitoyltransferase ZDHHC13 (ZDHHC13) LDTP08455 16.34  LDD2064 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 27.28  LDD2064 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 35.51  LDD2064 
Peripheral plasma membrane protein CASK (CASK) LDTP00482 11.71  LDD2064 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 14.52  LDD2064 
Peroxisomal bifunctional enzyme (EHHADH) LDTP05560 11.39  LDD2064 
Phosphatidylinositol 4-kinase type 2-alpha (PI4K2A) LDTP11209 10.85  LDD2064 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 15.24  LDD2064 
Phosphatidylserine synthase 1 (PTDSS1) LDTP04203 10.93  LDD2064 
Phosphatidylserine synthase 2 (PTDSS2) LDTP11284 12.64  LDD2064 
Plasma membrane calcium-transporting ATPase 4 (ATP2B4) LDTP03249 13.18  LDD2064 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 12.38  LDD2064 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 12.21  LDD2064 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 23.92  LDD2064 
Presequence protease, mitochondrial (PITRM1) LDTP07003 16.34  LDD2064 
Probable ATP-dependent RNA helicase DDX28 (DDX28) LDTP12633 26.35  LDD2064 
Prostaglandin E synthase 2 (PTGES2) LDTP12040 11.63  LDD2064 
Prostaglandin reductase 1 (PTGR1) LDTP06227 17.51  LDD2064 
Prostaglandin reductase 3 (PTGR3) LDTP15422 18.00  LDD2064 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 12.82  LDD2064 
Proteasome subunit beta type-4 (PSMB4) LDTP03417 11.16  LDD2064 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 12.04  LDD2064 
Protein disulfide-isomerase TMX3 (TMX3) LDTP10471 10.85  LDD2064 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 12.73  LDD2064 
Protein phosphatase methylesterase 1 (PPME1) LDTP14092 11.63  LDD2064 
Protein SCO1 homolog, mitochondrial (SCO1) LDTP01335 12.73  LDD2064 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 29.24  LDD2064 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 11.16  LDD2064 
Ras-related protein Rab-24 (RAB24) LDTP10020 16.80  LDD2064 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 13.27  LDD2064 
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) LDTP00907 11.47  LDD2064 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 12.82  LDD2064 
Retinol dehydrogenase 13 (RDH13) LDTP09061 15.03  LDD2064 
Ribosomal protein S6 kinase alpha-1 (RPS6KA1) LDTP06384 12.64  LDD2064 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 24.08  LDD2064 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 11.24  LDD2064 
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (ATP2A2) LDTP02860 17.03  LDD2064 
Serine palmitoyltransferase 1 (SPTLC1) LDTP00597 12.64  LDD2064 
Serine/threonine-protein kinase OSR1 (OXSR1) LDTP01664 10.85  LDD2064 
Serine/threonine-protein kinase VRK2 (VRK2) LDTP08378 11.47  LDD2064 
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (PPP2R5E) LDTP06546 21.11  LDD2064 
Serum paraoxonase/arylesterase 2 (PON2) LDTP06333 12.38  LDD2064 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 34.78  LDD2064 
Signal peptidase complex subunit 2 (SPCS2) LDTP06270 12.82  LDD2064 
Sphingolipid delta(4)-desaturase DES1 (DEGS1) LDTP00544 44.32  LDD2064 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 20.39  LDD2064 
Squalene monooxygenase (SQLE) LDTP06142 16.34  LDD2064 
Squalene synthase (FDFT1) LDTP03842 12.64  LDD2064 
Stearoyl-CoA desaturase (SCD) LDTP00344 13.93  LDD2064 
Thioredoxin domain-containing protein 16 (TXNDC16) LDTP13058 14.32  LDD2064 
Thioredoxin, mitochondrial (TXN2) LDTP10973 19.16  LDD2064 
Thioredoxin-like protein 1 (TXNL1) LDTP00758 17.51  LDD2064 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 20.39  LDD2064 
Torsin-1B (TOR1B) LDTP00400 11.16  LDD2064 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 14.52  LDD2064 
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADVL) LDTP04289 18.90  LDD2064 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 14.83  LDD2064 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 11.63  LDD2064 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 22.63  LDD2064 
X-ray repair cross-complementing protein 6 (XRCC6) LDTP02640 20.39  LDD2064 
------------------------------------------------------------------------------------
⏷ Show the Full List of 150 Enzyme
111 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
45 kDa calcium-binding protein (SDF4) LDTP11116 16.00  LDD2064 
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 13.83  LDD2064 
Acyl-CoA-binding domain-containing protein 5 (ACBD5) LDTP07152 18.00  LDD2064 
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 20.97  LDD2064 
ADP/ATP translocase 1 (SLC25A4) LDTP02608 17.03  LDD2064 
Amyloid-beta precursor protein (APP) LDTP02071 18.64  LDD2064 
Apoptosis regulator BAX (BAX) LDTP05528 11.16  LDD2064 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 13.64  LDD2064 
ATP synthase subunit e, mitochondrial (ATP5ME) LDTP14717 13.45  LDD2064 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 31.56  LDD2064 
Autophagy-related protein 9A (ATG9A) LDTP08030 11.16  LDD2064 
BRI3-binding protein (BRI3BP) LDTP15648 53.08  LDD2064 
Bridge-like lipid transfer protein family member 3A (BLTP3A) LDTP07361 10.85  LDD2064 
Calnexin (CANX) LDTP03405 14.83  LDD2064 
Chloride channel CLIC-like protein 1 (CLCC1) LDTP10804 13.55  LDD2064 
Complex I assembly factor TMEM126B, mitochondrial (TMEM126B) LDTP08469 17.39  LDD2064 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 19.16  LDD2064 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 99.73  LDD2064 
Cytoskeleton-associated protein 4 (CKAP4) LDTP05511 20.25  LDD2064 
Derlin-1 (DERL1) LDTP11245 11.71  LDD2064 
Derlin-2 (DERL2) LDTP11634 20.53  LDD2064 
Endophilin-B1 (SH3GLB1) LDTP13953 12.91  LDD2064 
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) LDTP12331 14.03  LDD2064 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 40.22  LDD2064 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 49.87  LDD2064 
Flotillin-1 (FLOT1) LDTP01366 12.73  LDD2064 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 25.63  LDD2064 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 14.03  LDD2064 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 12.30  LDD2064 
Importin-4 (IPO4) LDTP09515 12.47  LDD2064 
Intermembrane lipid transfer protein VPS13A (VPS13A) LDTP10769 14.12  LDD2064 
Leucine-rich repeat-containing protein 59 (LRRC59) LDTP10081 11.96  LDD2064 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 22.78  LDD2064 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 18.13  LDD2064 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 30.48  LDD2064 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 25.81  LDD2064 
Metaxin-1 (MTX1) LDTP05900 20.25  LDD2064 
MICOS complex subunit MIC26 (APOO) LDTP11250 18.51  LDD2064 
MICOS complex subunit MIC60 (IMMT) LDTP06660 11.71  LDD2064 
Mitochondrial carrier homolog 1 (MTCH1) LDTP12909 14.22  LDD2064 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 51.63  LDD2064 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 46.21  LDD2064 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 21.41  LDD2064 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 99.73  LDD2064 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 70.52  LDD2064 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 14.52  LDD2064 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 52.35  LDD2064 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 16.34  LDD2064 
Mitochondrial proton/calcium exchanger protein (LETM1) LDTP01525 11.16  LDD2064 
Mitochondrial pyruvate carrier 1 (MPC1) LDTP14163 23.43  LDD2064 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 25.11  LDD2064 
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) LDTP12210 13.27  LDD2064 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 12.82  LDD2064 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 11.79  LDD2064 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 12.47  LDD2064 
Nucleoporin NDC1 (NDC1) LDTP11213 12.04  LDD2064 
Nucleoporin Nup37 (NUP37) LDTP09203 12.38  LDD2064 
PAT complex subunit CCDC47 (CCDC47) LDTP10059 18.00  LDD2064 
Pericentriolar material 1 protein (PCM1) LDTP06331 11.79  LDD2064 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 19.16  LDD2064 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 22.94  LDD2064 
Peroxisomal membrane protein PEX14 (PEX14) LDTP01200 18.13  LDD2064 
PRA1 family protein 2 (PRAF2) LDTP01060 15.35  LDD2064 
Prosaposin (PSAP) LDTP02215 30.48  LDD2064 
Protein GPR107 (GPR107) LDTP07236 18.77  LDD2064 
Protein GPR108 (GPR108) LDTP12383 21.71  LDD2064 
Protein RER1 (RER1) LDTP00590 11.31  LDD2064 
Protein RFT1 homolog (RFT1) LDTP10073 13.00  LDD2064 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 12.47  LDD2064 
Protein tweety homolog 3 (TTYH3) LDTP11615 13.64  LDD2064 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 20.68  LDD2064 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 54.19  LDD2064 
Reticulon-1 (RTN1) LDTP06633 11.39  LDD2064 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 11.24  LDD2064 
Sideroflexin-2 (SFXN2) LDTP10621 15.24  LDD2064 
Sideroflexin-4 (SFXN4) LDTP07531 15.78  LDD2064 
Sigma intracellular receptor 2 (TMEM97) LDTP06945 16.68  LDD2064 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 15.35  LDD2064 
Sodium-dependent neutral amino acid transporter B(0)AT2 (SLC6A15) LDTP11826 15.45  LDD2064 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 99.73  LDD2064 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 36.00  LDD2064 
Sorting and assembly machinery component 50 homolog (SAMM50) LDTP14084 12.04  LDD2064 
StAR-related lipid transfer protein 7, mitochondrial (STARD7) LDTP18459 12.64  LDD2064 
STARD3 N-terminal-like protein (STARD3NL) LDTP01671 12.47  LDD2064 
SUN domain-containing protein 2 (SUN2) LDTP13256 11.88  LDD2064 
Surfeit locus protein 4 (SURF4) LDTP00592 22.01  LDD2064 
Synaptojanin-2-binding protein (SYNJ2BP) LDTP04789 17.15  LDD2064 
Syntaxin-5 (STX5) LDTP05780 18.38  LDD2064 
Thioredoxin-related transmembrane protein 2 (TMX2) LDTP13943 10.93  LDD2064 
THO complex subunit 5 homolog (THOC5) LDTP05978 12.21  LDD2064 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 25.46  LDD2064 
Translocation protein SEC63 homolog (SEC63) LDTP13243 13.27  LDD2064 
Translocator protein (TSPO) LDTP03546 14.42  LDD2064 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 44.32  LDD2064 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 38.05  LDD2064 
Transmembrane emp24 domain-containing protein 2 (TMED2) LDTP06365 13.93  LDD2064 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 12.21  LDD2064 
Transmembrane protein 160 (TMEM160) LDTP20002 71.51  LDD2064 
Transmembrane protein 199 (TMEM199) LDTP08881 56.89  LDD2064 
Transmembrane protein 201 (TMEM201) LDTP07058 13.83  LDD2064 
Transmembrane protein 205 (TMEM205) LDTP07667 18.51  LDD2064 
Transmembrane protein 214 (TMEM214) LDTP07477 12.30  LDD2064 
Transmembrane protein 230 (TMEM230) LDTP10065 17.27  LDD2064 
Transmembrane protein 87A (TMEM87A) LDTP15481 22.01  LDD2064 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 14.83  LDD2064 
Vezatin (VEZT) LDTP12191 12.21  LDD2064 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 28.25  LDD2064 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 23.43  LDD2064 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 20.68  LDD2064 
Wolframin (WFS1) LDTP01380 11.79  LDD2064 
Zinc transporter ZIP11 (SLC39A11) LDTP17682 49.52  LDD2064 
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⏷ Show the Full List of 111 Transporter and channel
3 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
DNA polymerase epsilon subunit 4 (POLE4) LDTP12471 23.43  LDD2064 
DnaJ homolog subfamily C member 1 (DNAJC1) LDTP10501 20.68  LDD2064 
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 11.31  LDD2064 
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1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Basigin (BSG) LDTP03772 11.55  LDD2064 
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122 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
14-3-3 protein eta (YWHAH) LDTP05442 11.31  LDD2064 
Actin-related protein 8 (ACTR8) LDTP12082 11.31  LDD2064 
Alpha-internexin (INA) LDTP06527 15.14  LDD2064 
Amyloid beta precursor like protein 2 (APLP2) LDTP05491 13.93  LDD2064 
Anaphase-promoting complex subunit 5 (ANAPC5) LDTP13410 10.93  LDD2064 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 12.21  LDD2064 
Apolipoprotein L2 (APOL2) LDTP11076 99.73  LDD2064 
Bcl-2-like protein 13 (BCL2L13) LDTP11389 12.30  LDD2064 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 10.85  LDD2064 
BSD domain-containing protein 1 (BSDC1) LDTP16116 13.64  LDD2064 
Calumenin (CALU) LDTP00887 19.43  LDD2064 
CCR4-NOT transcription complex subunit 2 (CNOT2) LDTP12925 17.88  LDD2064 
Centrosomal protein 43 (CEP43) LDTP01652 11.31  LDD2064 
CLIP-associating protein 2 (CLASP2) LDTP01129 11.88  LDD2064 
Clustered mitochondria protein homolog (CLUH) LDTP14486 14.32  LDD2064 
Coiled-coil domain-containing protein 6 (CCDC6) LDTP06515 15.24  LDD2064 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 20.82  LDD2064 
Desmocollin-3 (DSC3) LDTP06154 11.55  LDD2064 
Dynactin subunit 2 (DCTN2) LDTP05922 18.25  LDD2064 
Dynactin subunit 3 (DCTN3) LDTP01359 14.52  LDD2064 
EF-hand calcium-binding domain-containing protein 14 (EFCAB14) LDTP19021 14.72  LDD2064 
Emerin (EMD) LDTP04356 17.63  LDD2064 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 17.88  LDD2064 
ER lumen protein-retaining receptor 2 (KDELR2) LDTP03678 44.94  LDD2064 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 13.45  LDD2064 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 11.47  LDD2064 
FUN14 domain-containing protein 2 (FUNDC2) LDTP11326 16.00  LDD2064 
Ganglioside GM2 activator (GM2A) LDTP02927 20.39  LDD2064 
Glycosylphosphatidylinositol anchor attachment 1 protein (GPAA1) LDTP00729 13.09  LDD2064 
Golgi apparatus protein 1 (GLG1) LDTP09920 12.82  LDD2064 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 99.73  LDD2064 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 23.43  LDD2064 
Golgi phosphoprotein 3-like (GOLPH3L) LDTP11910 15.14  LDD2064 
Golgi to ER traffic protein 4 homolog (GET4) LDTP07964 17.63  LDD2064 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 19.84  LDD2064 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 17.88  LDD2064 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 18.38  LDD2064 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 13.83  LDD2064 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 11.47  LDD2064 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 11.63  LDD2064 
Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 11.08  LDD2064 
HIG1 domain family member 1A, mitochondrial (HIGD1A) LDTP13797 28.84  LDD2064 
Immunoglobulin-binding protein 1 (IGBP1) LDTP05089 14.52  LDD2064 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 17.27  LDD2064 
Integral membrane protein GPR180 (GPR180) LDTP19625 13.55  LDD2064 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 25.11  LDD2064 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 35.51  LDD2064 
KIF-binding protein (KIFBP) LDTP10263 17.39  LDD2064 
Kinetochore protein Spc24 (SPC24) LDTP09069 17.39  LDD2064 
Lamina-associated polypeptide 2, isoform alpha (TMPO) LDTP03967 11.39  LDD2064 
Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) LDTP03968 13.83  LDD2064 
Large ribosomal subunit protein mL40 (MRPL40) LDTP12395 11.55  LDD2064 
Large ribosomal subunit protein uL24 (RPL26) LDTP04914 19.43  LDD2064 
LysM and putative peptidoglycan-binding domain-containing protein 3 (LYSMD3) LDTP15240 14.93  LDD2064 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 14.83  LDD2064 
Membralin (TMEM259) LDTP14939 22.78  LDD2064 
MICOS complex subunit MIC13 (MICOS13) LDTP07274 16.00  LDD2064 
MICOS complex subunit MIC27 (APOOL) LDTP07718 12.21  LDD2064 
Mitochondrial fission process protein 1 (MTFP1) LDTP16192 54.57  LDD2064 
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) LDTP16322 20.53  LDD2064 
Mitochondrial import receptor subunit TOM20 homolog (TOMM20) LDTP06373 17.51  LDD2064 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 99.73  LDD2064 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 62.25  LDD2064 
Myomegalin (PDE4DIP) LDTP07221 14.72  LDD2064 
Neurofilament light polypeptide (NEFL) LDTP02180 19.29  LDD2064 
Neurofilament medium polypeptide (NEFM) LDTP02181 12.21  LDD2064 
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (NFU1) LDTP13622 11.31  LDD2064 
Nischarin (NISCH) LDTP13870 11.55  LDD2064 
NLR family member X1 (NLRX1) LDTP08248 10.85  LDD2064 
Nucleobindin-1 (NUCB1) LDTP05375 32.67  LDD2064 
Nucleobindin-2 (NUCB2) LDTP05160 95.67  LDD2064 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 11.79  LDD2064 
Nurim (NRM) LDTP08606 17.03  LDD2064 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 24.42  LDD2064 
Peroxisomal targeting signal 1 receptor (PEX5) LDTP04369 10.93  LDD2064 
Prefoldin subunit 2 (PFDN2) LDTP13309 11.08  LDD2064 
Programmed cell death protein 5 (PDCD5) LDTP00417 11.47  LDD2064 
Prohibitin-2 (PHB2) LDTP10924 11.24  LDD2064 
Protein bicaudal D homolog 2 (BICD2) LDTP09410 11.63  LDD2064 
Protein CEBPZOS (CEBPZOS) LDTP18883 60.13  LDD2064 
Protein FAM114A2 (FAM114A2) LDTP16080 31.56  LDD2064 
Protein FAM136A (FAM136A) LDTP18132 12.04  LDD2064 
Protein FAM162A (FAM162A) LDTP10056 84.45  LDD2064 
Protein FAM177A1 (FAM177A1) LDTP15398 14.22  LDD2064 
Protein FAM3C (FAM3C) LDTP09773 29.04  LDD2064 
Protein GOLM2 (GOLM2) LDTP15115 16.11  LDD2064 
Protein jagunal homolog 1 (JAGN1) LDTP08904 19.97  LDD2064 
Protein LYRIC (MTDH) LDTP08224 19.29  LDD2064 
Protein misato homolog 1 (MSTO1) LDTP11239 14.52  LDD2064 
Protein NipSnap homolog 1 (NIPSNAP1) LDTP19912 19.03  LDD2064 
Protein SET (SET) LDTP05277 19.70  LDD2064 
Protein YIF1A (YIF1A) LDTP01494 14.62  LDD2064 
RAD50-interacting protein 1 (RINT1) LDTP07476 15.67  LDD2064 
Receptor expression-enhancing protein 3 (REEP3) LDTP15095 19.56  LDD2064 
Receptor expression-enhancing protein 4 (REEP4) LDTP11981 14.12  LDD2064 
Receptor expression-enhancing protein 5 (REEP5) LDTP05257 10.85  LDD2064 
Regulator of microtubule dynamics protein 3 (RMDN3) LDTP10849 14.03  LDD2064 
Reticulocalbin-2 (RCN2) LDTP06097 17.51  LDD2064 
Reticulon-2 (RTN2) LDTP01167 12.13  LDD2064 
Reticulon-3 (RTN3) LDTP01522 50.21  LDD2064 
Reticulon-4 (RTN4) LDTP12412 41.64  LDD2064 
RNA-binding protein EWS (EWSR1) LDTP05318 11.39  LDD2064 
RNA-binding protein FUS (FUS) LDTP03775 10.85  LDD2064 
RNA-binding protein Musashi homolog 1 (MSI1) LDTP14453 10.85  LDD2064 
Signal recognition particle receptor subunit beta (SRPRB) LDTP16323 19.56  LDD2064 
SLC35A4 upstream open reading frame protein (SLC35A4) LDTP19005 15.78  LDD2064 
Small integral membrane protein 12 (SMIM12) LDTP19859 74.03  LDD2064 
Synaptic vesicle glycoprotein 2A (SV2A) LDTP07934 21.41  LDD2064 
Syntaxin-18 (STX18) LDTP13086 32.67  LDD2064 
Tetraspanin-6 (TSPAN6) LDTP14458 13.74  LDD2064 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 11.00  LDD2064 
Tetratricopeptide repeat protein 38 (TTC38) LDTP19372 14.32  LDD2064 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 49.87  LDD2064 
TraB domain-containing protein (TRABD) LDTP19963 34.54  LDD2064 
Transducin beta-like protein 2 (TBL2) LDTP16285 11.71  LDD2064 
Transformer-2 protein homolog alpha (TRA2A) LDTP05937 11.63  LDD2064 
Trophoblast glycoprotein (TPBG) LDTP05960 11.24  LDD2064 
Tudor and KH domain-containing protein (TDRKH) LDTP13922 15.67  LDD2064 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 46.53  LDD2064 
UV excision repair protein RAD23 homolog A (RAD23A) LDTP04626 17.88  LDD2064 
Vacuolar protein sorting-associated protein 51 homolog (VPS51) LDTP13338 13.36  LDD2064 
Vimentin (VIM) LDTP02297 19.84  LDD2064 
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⏷ Show the Full List of 122 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD2064 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587