Details of the Target
General Information of Target
| Target ID | LDTP17682 | |||||
|---|---|---|---|---|---|---|
| Target Name | Zinc transporter ZIP11 (SLC39A11) | |||||
| Gene Name | SLC39A11 | |||||
| Gene ID | 201266 | |||||
| Synonyms |
C17orf26; ZIP11; Zinc transporter ZIP11; Solute carrier family 39 member 11; Zrt- and Irt-like protein 11; ZIP-11 |
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| 3D Structure | ||||||
| Sequence |
MDGEAVRFCTDNQCVSLHPQEVDSVAMAPAAPKIPRLVQATPAFMAVTLVFSLVTLFVVV
QQQTRPVPKPVQAVILGDNITGHLPFEPNNHHHFGREAEMRELIQTFKGHMENSSAWVVE IQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEI QRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQA QLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNS QTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQ VFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAE IQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSL YYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRW TDGTPFNAAQNKAPGSKGSCPLRKYIIVNSGMGACSFIDTPPCPWILSN |
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| Target Bioclass |
Transporter and channel
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| Family |
ZIP transporter (TC 2.A.5) family
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| Subcellular location |
Cell membrane
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| Function |
Zinc importer that regulates cytosolic zinc concentrations either via zinc influx from the extracellular compartment or efflux from intracellular organelles such as Golgi apparatus. May transport copper ions as well. The transport mechanism remains to be elucidated.
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| Uniprot ID | ||||||
| Ensemble ID | ||||||
| HGNC ID | ||||||
Probe(s) Labeling This Target
PAL-AfBPP Probe
| Probe name | Structure | Binding Site(Ratio) | Interaction ID | Ref | |
|---|---|---|---|---|---|
|
C055 Probe Info |
 |
29.65 | LDD1752 | [1] | |
|
C056 Probe Info |
 |
22.94 | LDD1753 | [1] | |
|
C106 Probe Info |
 |
25.28 | LDD1793 | [1] | |
|
C107 Probe Info |
 |
7.26 | LDD1794 | [1] | |
|
C108 Probe Info |
 |
8.51 | LDD1795 | [1] | |
|
C186 Probe Info |
 |
7.78 | LDD1864 | [1] | |
|
C407 Probe Info |
 |
49.52 | LDD2064 | [1] | |
The Interaction Atlas With This Target