Details of the Probe

General Information of Probe

Probe ID
LDPC0424
Probe Name
C186
Synonyms
Z4282860423
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 428
Lipid-water partition coefficient (xlogp) 3.7
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C23H30ClN5O
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-1-[4-[4-(2-chlorophenyl)piperazin-1-yl]piperidin-1-yl]propan-1-one
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)N2CCC(CC2)N3CCN(CC3)C4=CC=CC=C4Cl
InChI
InChI=1S/C23H30ClN5O/c1-2-3-11-23(25-26-23)12-8-22(30)29-13-9-19(10-14-29)27-15-17-28(18-16-27)21-7-5-4-6-20(21)24/h1,4-7,19H,3,8-18H2
InChIKey
XJJUMNVNYSIFMR-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

115 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (EBP) LDTP06325 11.71  LDD1864 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 28.05  LDD1864 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 20.97  LDD1864 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 8.82  LDD1864 
Acid ceramidase (ASAH1) LDTP05905 17.15  LDD1864 
ADP-dependent glucokinase (ADPGK) LDTP11127 8.82  LDD1864 
ADP-ribosylation factor 4 (ARF4) LDTP02942 9.85  LDD1864 
ADP-ribosylation factor 5 (ARF5) LDTP05193 9.99  LDD1864 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 11.39  LDD1864 
Alpha-galactosidase A (GLA) LDTP02141 18.25  LDD1864 
Alpha-N-acetylglucosaminidase (NAGLU) LDTP04634 17.03  LDD1864 
Atlastin-2 (ATL2) LDTP09251 9.19  LDD1864 
Beta-1,4-glucuronyltransferase 1 (B4GAT1) LDTP00783 17.39  LDD1864 
Beta-galactosidase (GLB1) LDTP02837 11.63  LDD1864 
Beta-glucuronidase (GUSB) LDTP02260 13.83  LDD1864 
Beta-hexosaminidase subunit alpha (HEXA) LDTP02169 15.14  LDD1864 
Beta-hexosaminidase subunit beta (HEXB) LDTP02216 11.16  LDD1864 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 27.67  LDD1864 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 13.09  LDD1864 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 16.22  LDD1864 
Carboxypeptidase D (CPD) LDTP01372 14.12  LDD1864 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 10.78  LDD1864 
Catechol O-methyltransferase (COMT) LDTP03145 13.64  LDD1864 
Cathepsin Z (CTSZ) LDTP13147 28.44  LDD1864 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 13.74  LDD1864 
Ceramide glucosyltransferase (UGCG) LDTP06617 9.78  LDD1864 
Ceramide synthase 2 (CERS2) LDTP10329 12.82  LDD1864 
Choline kinase alpha (CHKA) LDTP03787 9.99  LDD1864 
Copper-transporting ATPase 1 (ATP7A) LDTP05422 12.82  LDD1864 
Cytochrome b-c1 complex subunit 8 (UQCRQ) LDTP00486 14.62  LDD1864 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 9.38  LDD1864 
Cytochrome b5 type B (CYB5B) LDTP00697 27.47  LDD1864 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 30.48  LDD1864 
Diacylglycerol lipase-beta (DAGLB) LDTP09095 20.11  LDD1864 
Dipeptidyl peptidase 1 (CTSC) LDTP04572 11.88  LDD1864 
DNA-directed RNA polymerase III subunit RPC3 (POLR3C) LDTP11237 8.28  LDD1864 
Dolichyldiphosphatase 1 (DOLPP1) LDTP15328 13.93  LDD1864 
E3 ubiquitin-protein ligase AMFR (AMFR) LDTP13491 8.82  LDD1864 
E3 ubiquitin-protein ligase HECTD1 (HECTD1) LDTP13574 7.89  LDD1864 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 7.78  LDD1864 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 10.13  LDD1864 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 21.56  LDD1864 
Gamma-glutamyl hydrolase (GGH) LDTP09886 13.18  LDD1864 
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase (ALG11) LDTP06721 9.45  LDD1864 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 13.83  LDD1864 
Glycosyltransferase 8 domain-containing protein 1 (GLT8D1) LDTP17305 13.45  LDD1864 
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) LDTP12763 9.71  LDD1864 
GTP-binding protein SAR1a (SAR1A) LDTP12470 8.63  LDD1864 
Heme oxygenase 1 (HMOX1) LDTP02359 12.55  LDD1864 
Heme oxygenase 2 (HMOX2) LDTP03540 10.70  LDD1864 
Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) LDTP07990 10.70  LDD1864 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 14.72  LDD1864 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 18.13  LDD1864 
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) LDTP04211 15.03  LDD1864 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 20.25  LDD1864 
Legumain (LGMN) LDTP10888 16.45  LDD1864 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 28.05  LDD1864 
Leukotriene A-4 hydrolase (LTA4H) LDTP02385 8.88  LDD1864 
Lysine-specific histone demethylase 2 (KDM1B) LDTP09043 11.71  LDD1864 
Lysophosphatidylcholine acyltransferase 1 (LPCAT1) LDTP09188 10.34  LDD1864 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 11.79  LDD1864 
Lysosomal acid phosphatase (ACP2) LDTP02539 18.77  LDD1864 
Lysosomal alpha-glucosidase (GAA) LDTP02486 10.85  LDD1864 
Lysosomal alpha-mannosidase (MAN2B1) LDTP00338 10.20  LDD1864 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 9.38  LDD1864 
Lysosomal protective protein (CTSA) LDTP02505 32.22  LDD1864 
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) LDTP10930 11.79  LDD1864 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 12.13  LDD1864 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 14.32  LDD1864 
Mitochondrial intermediate peptidase (MIPEP) LDTP10981 12.82  LDD1864 
Mitochondrial-processing peptidase subunit alpha (PMPCA) LDTP05632 12.47  LDD1864 
N-acetylglucosamine-6-sulfatase (GNS) LDTP02799 17.63  LDD1864 
N-alpha-acetyltransferase 15, NatA auxiliary subunit (NAA15) LDTP11388 10.70  LDD1864 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 9.19  LDD1864 
NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) LDTP08385 14.32  LDD1864 
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) LDTP12959 10.63  LDD1864 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 36.00  LDD1864 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 12.47  LDD1864 
Nardilysin (NRDC) LDTP00886 13.55  LDD1864 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 67.18  LDD1864 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 39.67  LDD1864 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 11.00  LDD1864 
Peptidyl-prolyl cis-trans isomerase FKBP7 (FKBP7) LDTP14218 26.17  LDD1864 
Peroxisomal trans-2-enoyl-CoA reductase (PECR) LDTP11437 8.28  LDD1864 
Phosphatidylserine decarboxylase proenzyme, mitochondrial (PISD) LDTP13220 9.65  LDD1864 
Plasma alpha-L-fucosidase (FUCA2) LDTP11215 13.27  LDD1864 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 8.40  LDD1864 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 21.56  LDD1864 
Prenylcysteine oxidase-like (PCYOX1L) LDTP15480 10.34  LDD1864 
Probable serine carboxypeptidase CPVL (CPVL) LDTP15988 8.88  LDD1864 
Prostaglandin reductase 3 (PTGR3) LDTP15422 29.65  LDD1864 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 21.56  LDD1864 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 14.32  LDD1864 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 23.43  LDD1864 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 15.14  LDD1864 
Putative phospholipase B-like 2 (PLBD2) LDTP09256 36.76  LDD1864 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 15.03  LDD1864 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 26.72  LDD1864 
Ribonuclease T2 (RNASET2) LDTP00316 20.97  LDD1864 
Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B) LDTP07989 8.82  LDD1864 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 14.32  LDD1864 
Signal peptidase complex catalytic subunit SEC11C (SEC11C) LDTP11438 8.28  LDD1864 
Signal peptide peptidase-like 2A (SPPL2A) LDTP09395 35.75  LDD1864 
Sphingosine-1-phosphate lyase 1 (SGPL1) LDTP01613 19.84  LDD1864 
Tissue alpha-L-fucosidase (FUCA1) LDTP02006 30.48  LDD1864 
TLC domain-containing protein 1 (TLCD1) LDTP10182 30.48  LDD1864 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 7.94  LDD1864 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 45.89  LDD1864 
Ubiquitin carboxyl-terminal hydrolase 11 (USP11) LDTP04456 17.63  LDD1864 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 14.22  LDD1864 
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) LDTP12954 8.69  LDD1864 
Very-long-chain enoyl-CoA reductase (TECR) LDTP12867 25.81  LDD1864 
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) LDTP08728 28.64  LDD1864 
Vitamin K-dependent gamma-carboxylase (GGCX) LDTP03854 8.11  LDD1864 
X-ray repair cross-complementing protein 6 (XRCC6) LDTP02640 15.35  LDD1864 
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⏷ Show the Full List of 115 Enzyme
76 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) LDTP09328 13.09  LDD1864 
Amyloid-beta precursor protein (APP) LDTP02071 16.11  LDD1864 
Anoctamin-6 (ANO6) LDTP06855 8.00  LDD1864 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 10.06  LDD1864 
Cation-independent mannose-6-phosphate receptor (IGF2R) LDTP02586 14.83  LDD1864 
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (COX16) LDTP16163 13.00  LDD1864 
Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) LDTP08981 8.11  LDD1864 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 37.01  LDD1864 
Derlin-1 (DERL1) LDTP11245 10.63  LDD1864 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 76.11  LDD1864 
ER membrane protein complex subunit 5 (MMGT1) LDTP08878 33.13  LDD1864 
Golgi SNAP receptor complex member 1 (GOSR1) LDTP01542 15.56  LDD1864 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 9.25  LDD1864 
H(+)/Cl(-) exchange transporter 3 (CLCN3) LDTP04459 15.45  LDD1864 
High affinity cationic amino acid transporter 1 (SLC7A1) LDTP03559 15.78  LDD1864 
Importin-7 (IPO7) LDTP01574 11.96  LDD1864 
Integral membrane protein 2B (ITM2B) LDTP13833 15.24  LDD1864 
Integral membrane protein 2C (ITM2C) LDTP12451 16.80  LDD1864 
Lipid scramblase CLPTM1L (CLPTM1L) LDTP10499 8.22  LDD1864 
Lysosome membrane protein 2 (SCARB2) LDTP06034 15.78  LDD1864 
Lysosome-associated membrane glycoprotein 1 (LAMP1) LDTP02562 22.01  LDD1864 
Lysosome-associated membrane glycoprotein 2 (LAMP2) LDTP02655 12.64  LDD1864 
Melanoma inhibitory activity protein 2 (MIA2) LDTP10669 7.84  LDD1864 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 8.63  LDD1864 
MICOS complex subunit MIC26 (APOO) LDTP11250 8.17  LDD1864 
Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) LDTP11095 13.83  LDD1864 
Mitochondrial carrier homolog 2 (MTCH2) LDTP14235 7.62  LDD1864 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 19.03  LDD1864 
Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) LDTP13983 10.41  LDD1864 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 39.40  LDD1864 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 50.91  LDD1864 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 8.34  LDD1864 
Mitochondrial import receptor subunit TOM40 homolog (TOMM40) LDTP01748 8.46  LDD1864 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 23.92  LDD1864 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 9.78  LDD1864 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 15.78  LDD1864 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 18.13  LDD1864 
NPC intracellular cholesterol transporter 2 (NPC2) LDTP04940 21.71  LDD1864 
Nucleoporin NDC1 (NDC1) LDTP11213 7.62  LDD1864 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 8.17  LDD1864 
Prosaposin (PSAP) LDTP02215 22.16  LDD1864 
Protein FAM8A1 (FAM8A1) LDTP16190 8.22  LDD1864 
Protein GPR107 (GPR107) LDTP07236 28.64  LDD1864 
Protein sel-1 homolog 1 (SEL1L) LDTP13164 9.92  LDD1864 
Protein tweety homolog 3 (TTYH3) LDTP11615 48.17  LDD1864 
Proton-coupled amino acid transporter 1 (SLC36A1) LDTP08016 11.47  LDD1864 
Proton-coupled zinc antiporter SLC30A5 (SLC30A5) LDTP09294 12.64  LDD1864 
Putative divalent cation/proton antiporter TMEM165 (TMEM165) LDTP12207 8.34  LDD1864 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 7.57  LDD1864 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 11.88  LDD1864 
Secretory carrier-associated membrane protein 2 (SCAMP2) LDTP00547 14.12  LDD1864 
Sideroflexin-2 (SFXN2) LDTP10621 8.06  LDD1864 
Sideroflexin-4 (SFXN4) LDTP07531 7.73  LDD1864 
Sodium-coupled neutral amino acid symporter 2 (SLC38A2) LDTP10731 7.62  LDD1864 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 48.84  LDD1864 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 23.75  LDD1864 
Sortilin (SORT1) LDTP10885 8.06  LDD1864 
Surfeit locus protein 4 (SURF4) LDTP00592 10.20  LDD1864 
Syntaxin-3 (STX3) LDTP05811 8.82  LDD1864 
Syntaxin-6 (STX6) LDTP00857 15.45  LDD1864 
Tetraspanin-3 (TSPAN3) LDTP16813 52.35  LDD1864 
Transferrin receptor protein 1 (TFRC) LDTP01969 9.71  LDD1864 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 11.96  LDD1864 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 21.26  LDD1864 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 10.48  LDD1864 
Transmembrane 9 superfamily member 4 (TM9SF4) LDTP09789 8.06  LDD1864 
Transmembrane protein 126A (TMEM126A) LDTP15948 44.02  LDD1864 
Transmembrane protein 160 (TMEM160) LDTP20002 24.25  LDD1864 
Transmembrane protein 199 (TMEM199) LDTP08881 28.25  LDD1864 
Transmembrane protein 230 (TMEM230) LDTP10065 8.63  LDD1864 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 19.29  LDD1864 
V-type proton ATPase subunit S1 (ATP6AP1) LDTP06499 8.11  LDD1864 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 22.47  LDD1864 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 21.56  LDD1864 
Voltage-dependent anion-selective channel protein 3 (VDAC3) LDTP13824 9.06  LDD1864 
Zinc transporter ZIP11 (SLC39A11) LDTP17682 7.78  LDD1864 
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⏷ Show the Full List of 76 Transporter and channel
5 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
HLA class I histocompatibility antigen, A alpha chain (HLA-A) LDTP02040 11.16  LDD1864 
HLA class I histocompatibility antigen, C alpha chain (HLA-C) LDTP02491 8.82  LDD1864 
Junctional adhesion molecule A (F11R) LDTP14203 7.62  LDD1864 
Leukocyte surface antigen CD47 (CD47) LDTP05572 7.94  LDD1864 
Neogenin (NEO1) LDTP09907 16.80  LDD1864 
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65 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
55 kDa erythrocyte membrane protein (MPP1) LDTP05233 7.78  LDD1864 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 11.00  LDD1864 
BCAS3 microtubule associated cell migration factor (BCAS3) LDTP12001 8.94  LDD1864 
C-type mannose receptor 2 (MRC2) LDTP13114 8.88  LDD1864 
Calumenin (CALU) LDTP00887 9.99  LDD1864 
Clustered mitochondria protein homolog (CLUH) LDTP14486 12.04  LDD1864 
Collectin-12 (COLEC12) LDTP07031 11.88  LDD1864 
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) LDTP13902 15.45  LDD1864 
DENN domain-containing protein 11 (DENND11) LDTP16577 14.83  LDD1864 
Divergent protein kinase domain 2A (DIPK2A) LDTP09143 11.79  LDD1864 
DNA damage-binding protein 1 (DDB1) LDTP06543 18.38  LDD1864 
DnaJ homolog subfamily C member 16 (DNAJC16) LDTP13863 10.93  LDD1864 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 12.73  LDD1864 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 13.45  LDD1864 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 27.10  LDD1864 
Galectin-3-binding protein (LGALS3BP) LDTP05558 25.28  LDD1864 
Gamma-tubulin complex component 3 (TUBGCP3) LDTP10191 11.16  LDD1864 
Ganglioside GM2 activator (GM2A) LDTP02927 23.26  LDD1864 
Golgi apparatus protein 1 (GLG1) LDTP09920 10.34  LDD1864 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 16.22  LDD1864 
Golgi phosphoprotein 3 (GOLPH3) LDTP11911 7.84  LDD1864 
HAUS augmin-like complex subunit 5 (HAUS5) LDTP01466 8.17  LDD1864 
HCLS1-associated protein X-1 (HAX1) LDTP00199 8.00  LDD1864 
Heat shock 70 kDa protein 13 (HSPA13) LDTP04207 8.06  LDD1864 
Keratinocyte-associated transmembrane protein 2 (KCT2) LDTP19780 14.22  LDD1864 
Kinetochore-associated protein 1 (KNTC1) LDTP04382 13.36  LDD1864 
Mammalian ependymin-related protein 1 (EPDR1) LDTP13606 13.93  LDD1864 
Membralin (TMEM259) LDTP14939 14.83  LDD1864 
Mitochondrial fission 1 protein (FIS1) LDTP13982 8.82  LDD1864 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 37.53  LDD1864 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 27.28  LDD1864 
Myomegalin (PDE4DIP) LDTP07221 8.34  LDD1864 
Negative elongation factor C/D (NELFCD) LDTP08594 19.43  LDD1864 
Nucleobindin-2 (NUCB2) LDTP05160 16.80  LDD1864 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 7.78  LDD1864 
OCIA domain-containing protein 1 (OCIAD1) LDTP12755 9.25  LDD1864 
Optic atrophy 3 protein (OPA3) LDTP16006 10.34  LDD1864 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 10.27  LDD1864 
Protein CEBPZOS (CEBPZOS) LDTP18883 18.00  LDD1864 
Protein ecdysoneless homolog (ECD) LDTP01711 8.69  LDD1864 
Protein FAM114A2 (FAM114A2) LDTP16080 8.57  LDD1864 
Protein FAM162A (FAM162A) LDTP10056 14.42  LDD1864 
Protein FAM3C (FAM3C) LDTP09773 7.89  LDD1864 
Protein misato homolog 1 (MSTO1) LDTP11239 13.09  LDD1864 
Protein Niban 2 (NIBAN2) LDTP10847 9.00  LDD1864 
Protein PBDC1 (PBDC1) LDTP19924 11.88  LDD1864 
Protein YIF1A (YIF1A) LDTP01494 12.21  LDD1864 
Reticulocalbin-2 (RCN2) LDTP06097 10.93  LDD1864 
Reticulon-3 (RTN3) LDTP01522 13.83  LDD1864 
Reticulon-4 (RTN4) LDTP12412 9.71  LDD1864 
Sequestosome-1 (SQSTM1) LDTP05898 12.73  LDD1864 
Small integral membrane protein 12 (SMIM12) LDTP19859 22.63  LDD1864 
Splicing factor U2AF 65 kDa subunit (U2AF2) LDTP03352 13.00  LDD1864 
Superkiller complex protein 3 (SKIC3) LDTP07574 9.85  LDD1864 
Synaptogyrin-2 (SYNGR2) LDTP00859 12.55  LDD1864 
Syntaxin-10 (STX10) LDTP00986 15.24  LDD1864 
Syntaxin-18 (STX18) LDTP13086 9.71  LDD1864 
Testis-expressed protein 264 (TEX264) LDTP14259 14.93  LDD1864 
Tetraspanin-6 (TSPAN6) LDTP14458 27.28  LDD1864 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 10.13  LDD1864 
Thioredoxin-related transmembrane protein 4 (TMX4) LDTP18373 11.88  LDD1864 
TraB domain-containing protein (TRABD) LDTP19963 8.57  LDD1864 
Trans-Golgi network integral membrane protein 2 (TGOLN2) LDTP00779 22.47  LDD1864 
Tubulin-specific chaperone E (TBCE) LDTP06479 7.94  LDD1864 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 19.16  LDD1864 
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⏷ Show the Full List of 65 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1864 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587