Details of the Target

General Information of Target

Target ID	LDTP03277
Target Name	ER lumen protein-retaining receptor 1 (KDELR1)
Gene Name	KDELR1
Gene ID	10945
Synonyms	ERD2.1; ER lumen protein-retaining receptor 1; KDEL endoplasmic reticulum protein retention receptor 1; KDEL receptor 1; Putative MAPK-activating protein PM23
3D Structure	Download 2D Sequence (FASTA) Download 3D Structure (PDB) Download
Sequence	MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVFTARYLDLFTNYISLYN TCMKVVYIACSFTTVWLIYSKFKATYDGNHDTFRVEFLVVPTAILAFLVNHDFTPLEILW TFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRTLYLFNWIWRYHFEGFFDLIA IVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA
Target Bioclass	Transporter and channel
Family	ERD2 family
Subcellular location	Golgi apparatus membrane
Function	Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum.
Uniprot ID	P24390
Ensemble ID	ENST00000330720.7
HGNC ID	HGNC:6304

Target Site Mutations in Different Cell Lines

Cell line	Mutation details			Probe for labeling this protein in this cell
LS180	SNV: p.Y191D			.

Probe(s) Labeling This Target

ABPP Probe

Click To Hide/Show 12 Probe Related to This Target

Probe name	Binding Site(Ratio)	Interaction ID	Ref
BTD Probe Info	C29(4.29)	LDD1699	[1]
Probe 1 Probe Info	Y86(11.90)	LDD3495	[2]
IPM Probe Info	C29(81.80)	LDD1701	[1]
DBIA Probe Info	C29(1.26)	LDD0531	[3]
5E-2FA Probe Info	N.A.	LDD2235	[4]
IA-alkyne Probe Info	N.A.	LDD0036	[5]
Lodoacetamide azide Probe Info	N.A.	LDD0037	[5]
TFBX Probe Info	N.A.	LDD0027	[6]
Compound 10 Probe Info	N.A.	LDD2216	[7]
Acrolein Probe Info	N.A.	LDD0217	[8]
Crotonaldehyde Probe Info	N.A.	LDD0219	[8]
AOyne Probe Info	8.90	LDD0443	[9]

PAL-AfBPP Probe

Click To Hide/Show 222 Probe Related to This Target

Probe name	Binding Site(Ratio)	Interaction ID	Ref
C001 Probe Info	12.04	LDD1711	[10]
C002 Probe Info	5.13	LDD1712	[10]
C003 Probe Info	18.13	LDD1713	[10]
C004 Probe Info	25.99	LDD1714	[10]
C007 Probe Info	18.13	LDD1716	[10]
C008 Probe Info	14.72	LDD1717	[10]
C010 Probe Info	16.80	LDD1719	[10]
C011 Probe Info	27.86	LDD1720	[10]
C017 Probe Info	6.50	LDD1725	[10]
C022 Probe Info	86.82	LDD1728	[10]
C026 Probe Info	37.53	LDD1732	[10]
C028 Probe Info	7.89	LDD1734	[10]
C039 Probe Info	9.92	LDD1739	[10]
C040 Probe Info	19.56	LDD1740	[10]
C041 Probe Info	17.03	LDD1741	[10]
C044 Probe Info	5.98	LDD1743	[10]
C049 Probe Info	38.59	LDD1747	[10]
C051 Probe Info	10.78	LDD1749	[10]
C052 Probe Info	13.93	LDD1750	[10]
C053 Probe Info	13.55	LDD1751	[10]
C055 Probe Info	30.48	LDD1752	[10]
C056 Probe Info	28.64	LDD1753	[10]
C059 Probe Info	21.71	LDD1756	[10]
C060 Probe Info	7.62	LDD1757	[10]
C063 Probe Info	42.81	LDD1760	[10]
C064 Probe Info	51.98	LDD1761	[10]
C065 Probe Info	6.11	LDD1762	[10]
C067 Probe Info	13.64	LDD1763	[10]
C070 Probe Info	24.08	LDD1766	[10]
C071 Probe Info	9.45	LDD1767	[10]
C072 Probe Info	17.39	LDD1768	[10]
C075 Probe Info	12.30	LDD1770	[10]
C078 Probe Info	6.15	LDD1771	[10]
C082 Probe Info	26.91	LDD1774	[10]
C083 Probe Info	7.84	LDD1775	[10]
C085 Probe Info	22.94	LDD1777	[10]
C086 Probe Info	5.46	LDD1778	[10]
C087 Probe Info	50.56	LDD1779	[10]
C089 Probe Info	7.11	LDD1781	[10]
C091 Probe Info	66.72	LDD1782	[10]
C092 Probe Info	99.73	LDD1783	[10]
C094 Probe Info	95.01	LDD1785	[10]
C095 Probe Info	18.13	LDD1786	[10]
C098 Probe Info	12.47	LDD1787	[10]
C099 Probe Info	9.99	LDD1788	[10]
C100 Probe Info	13.09	LDD1789	[10]
C102 Probe Info	5.46	LDD1790	[10]
C105 Probe Info	6.23	LDD1792	[10]
C106 Probe Info	99.73	LDD1793	[10]
C107 Probe Info	98.36	LDD1794	[10]
C108 Probe Info	99.73	LDD1795	[10]
C110 Probe Info	6.73	LDD1797	[10]
C112 Probe Info	99.73	LDD1799	[10]
C122 Probe Info	9.99	LDD1808	[10]
C129 Probe Info	18.00	LDD1811	[10]
C130 Probe Info	25.99	LDD1812	[10]
C134 Probe Info	51.63	LDD1816	[10]
C135 Probe Info	37.27	LDD1817	[10]
C139 Probe Info	20.53	LDD1821	[10]
C140 Probe Info	25.99	LDD1822	[10]
C141 Probe Info	30.48	LDD1823	[10]
C143 Probe Info	43.71	LDD1825	[10]
C147 Probe Info	17.51	LDD1829	[10]
C153 Probe Info	48.50	LDD1834	[10]
C156 Probe Info	11.24	LDD1836	[10]
C158 Probe Info	13.55	LDD1838	[10]
C159 Probe Info	49.87	LDD1839	[10]
C160 Probe Info	64.00	LDD1840	[10]
C161 Probe Info	69.07	LDD1841	[10]
C163 Probe Info	16.00	LDD1843	[10]
C165 Probe Info	17.51	LDD1845	[10]
C166 Probe Info	7.57	LDD1846	[10]
C169 Probe Info	89.88	LDD1849	[10]
C170 Probe Info	10.48	LDD1850	[10]
C173 Probe Info	5.28	LDD1853	[10]
C174 Probe Info	6.02	LDD1854	[10]
C177 Probe Info	15.78	LDD1856	[10]
C178 Probe Info	66.26	LDD1857	[10]
C183 Probe Info	32.90	LDD1861	[10]
C185 Probe Info	20.97	LDD1863	[10]
C186 Probe Info	76.11	LDD1864	[10]
C187 Probe Info	40.50	LDD1865	[10]
C191 Probe Info	12.82	LDD1868	[10]
C193 Probe Info	5.74	LDD1869	[10]
C194 Probe Info	22.78	LDD1870	[10]
C196 Probe Info	10.56	LDD1872	[10]
C197 Probe Info	8.46	LDD1873	[10]
C198 Probe Info	15.67	LDD1874	[10]
C201 Probe Info	99.73	LDD1877	[10]
C204 Probe Info	12.13	LDD1879	[10]
C205 Probe Info	7.57	LDD1880	[10]
C206 Probe Info	76.11	LDD1881	[10]
C207 Probe Info	24.59	LDD1882	[10]
C210 Probe Info	99.73	LDD1884	[10]
C211 Probe Info	43.11	LDD1885	[10]
C213 Probe Info	84.45	LDD1887	[10]
C214 Probe Info	7.73	LDD1888	[10]
C216 Probe Info	6.68	LDD1890	[10]
C217 Probe Info	6.50	LDD1891	[10]
C218 Probe Info	30.06	LDD1892	[10]
C219 Probe Info	23.26	LDD1893	[10]
C220 Probe Info	54.57	LDD1894	[10]
C222 Probe Info	5.13	LDD1896	[10]
C225 Probe Info	14.42	LDD1898	[10]
C226 Probe Info	9.38	LDD1899	[10]
C228 Probe Info	35.75	LDD1901	[10]
C229 Probe Info	16.45	LDD1902	[10]
C231 Probe Info	28.84	LDD1904	[10]
C232 Probe Info	35.75	LDD1905	[10]
C233 Probe Info	24.42	LDD1906	[10]
C234 Probe Info	8.46	LDD1907	[10]
C235 Probe Info	29.86	LDD1908	[10]
C238 Probe Info	13.09	LDD1911	[10]
C240 Probe Info	17.15	LDD1913	[10]
C243 Probe Info	28.25	LDD1916	[10]
C244 Probe Info	32.00	LDD1917	[10]
C245 Probe Info	19.97	LDD1918	[10]
C246 Probe Info	52.35	LDD1919	[10]
C249 Probe Info	35.02	LDD1922	[10]
C252 Probe Info	42.22	LDD1925	[10]
C255 Probe Info	17.63	LDD1928	[10]
C258 Probe Info	11.08	LDD1931	[10]
C260 Probe Info	11.16	LDD1932	[10]
C264 Probe Info	28.84	LDD1935	[10]
C265 Probe Info	23.92	LDD1936	[10]
C270 Probe Info	13.45	LDD1940	[10]
C271 Probe Info	9.32	LDD1941	[10]
C272 Probe Info	14.22	LDD1942	[10]
C273 Probe Info	34.78	LDD1943	[10]
C277 Probe Info	46.85	LDD1947	[10]
C278 Probe Info	70.03	LDD1948	[10]
C280 Probe Info	29.65	LDD1950	[10]
C282 Probe Info	43.71	LDD1952	[10]
C284 Probe Info	60.13	LDD1954	[10]
C285 Probe Info	24.25	LDD1955	[10]
C286 Probe Info	9.65	LDD1956	[10]
C287 Probe Info	34.06	LDD1957	[10]
C288 Probe Info	20.25	LDD1958	[10]
C289 Probe Info	25.46	LDD1959	[10]
C290 Probe Info	11.08	LDD1960	[10]
C292 Probe Info	5.28	LDD1962	[10]
C293 Probe Info	54.95	LDD1963	[10]
C296 Probe Info	63.56	LDD1966	[10]
C297 Probe Info	20.39	LDD1967	[10]
C299 Probe Info	35.75	LDD1968	[10]
C300 Probe Info	12.38	LDD1969	[10]
C301 Probe Info	9.71	LDD1970	[10]
C303 Probe Info	8.28	LDD1972	[10]
C304 Probe Info	8.22	LDD1973	[10]
C305 Probe Info	35.02	LDD1974	[10]
C307 Probe Info	30.48	LDD1975	[10]
C310 Probe Info	29.45	LDD1977	[10]
C311 Probe Info	6.59	LDD1978	[10]
C313 Probe Info	30.48	LDD1980	[10]
C314 Probe Info	70.52	LDD1981	[10]
C317 Probe Info	10.34	LDD1983	[10]
C320 Probe Info	14.03	LDD1986	[10]
C322 Probe Info	23.59	LDD1988	[10]
C326 Probe Info	35.51	LDD1990	[10]
C327 Probe Info	7.78	LDD1991	[10]
C328 Probe Info	5.86	LDD1992	[10]
C333 Probe Info	9.99	LDD1996	[10]
C337 Probe Info	5.94	LDD2000	[10]
C338 Probe Info	11.08	LDD2001	[10]
C339 Probe Info	17.51	LDD2002	[10]
C342 Probe Info	8.28	LDD2004	[10]
C343 Probe Info	38.85	LDD2005	[10]
C347 Probe Info	6.82	LDD2008	[10]
C348 Probe Info	61.82	LDD2009	[10]
C349 Probe Info	73.01	LDD2010	[10]
C350 Probe Info	93.70	LDD2011	[10]
C353 Probe Info	20.11	LDD2014	[10]
C354 Probe Info	44.63	LDD2015	[10]
C355 Probe Info	31.34	LDD2016	[10]
C356 Probe Info	34.78	LDD2017	[10]
C357 Probe Info	24.76	LDD2018	[10]
C360 Probe Info	7.31	LDD2021	[10]
C362 Probe Info	71.01	LDD2023	[10]
C363 Probe Info	44.94	LDD2024	[10]
C364 Probe Info	43.41	LDD2025	[10]
C366 Probe Info	18.38	LDD2027	[10]
C367 Probe Info	9.45	LDD2028	[10]
C373 Probe Info	11.47	LDD2033	[10]
C376 Probe Info	89.88	LDD2036	[10]
C378 Probe Info	31.12	LDD2037	[10]
C380 Probe Info	27.86	LDD2039	[10]
C382 Probe Info	52.35	LDD2041	[10]
C383 Probe Info	63.12	LDD2042	[10]
C386 Probe Info	29.86	LDD2045	[10]
C387 Probe Info	13.45	LDD2046	[10]
C388 Probe Info	63.12	LDD2047	[10]
C390 Probe Info	82.14	LDD2049	[10]
C391 Probe Info	49.87	LDD2050	[10]
C396 Probe Info	6.41	LDD2055	[10]
C405 Probe Info	31.56	LDD2063	[10]
C407 Probe Info	40.22	LDD2064	[10]
C408 Probe Info	10.56	LDD2065	[10]
C409 Probe Info	11.00	LDD2066	[10]
C413 Probe Info	55.72	LDD2069	[10]
C414 Probe Info	16.91	LDD2070	[10]
C416 Probe Info	12.21	LDD2071	[10]
C417 Probe Info	6.82	LDD2072	[10]
C418 Probe Info	8.34	LDD2073	[10]
C419 Probe Info	47.50	LDD2074	[10]
C420 Probe Info	42.52	LDD2075	[10]
C421 Probe Info	46.21	LDD2076	[10]
C422 Probe Info	21.26	LDD2077	[10]
C423 Probe Info	20.68	LDD2078	[10]
FFF probe11 Probe Info	20.00	LDD0471	[11]
FFF probe12 Probe Info	13.71	LDD0473	[11]
FFF probe13 Probe Info	20.00	LDD0475	[11]
FFF probe14 Probe Info	20.00	LDD0477	[11]
FFF probe15 Probe Info	20.00	LDD0478	[11]
FFF probe2 Probe Info	20.00	LDD0463	[11]
FFF probe3 Probe Info	20.00	LDD0464	[11]
FFF probe4 Probe Info	18.30	LDD0466	[11]
FFF probe6 Probe Info	20.00	LDD0467	[11]
FFF probe7 Probe Info	20.00	LDD0483	[11]
FFF probe9 Probe Info	20.00	LDD0470	[11]
JN0003 Probe Info	20.00	LDD0469	[11]
STS-1 Probe Info	N.A.	LDD0136	[12]
OEA-DA Probe Info	20.00	LDD0046	[13]

Competitor(s) Related to This Target

Competitor ID	Name	Cell line	Binding Site(Ratio)	Interaction ID	Ref
LDCM0548	1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one	MDA-MB-231	C29(1.16)	LDD2142	[1]
LDCM0519	1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one	MDA-MB-231	C29(1.17)	LDD2112	[1]
LDCM0502	1-(Cyanoacetyl)piperidine	MDA-MB-231	C29(0.56)	LDD2095	[1]
LDCM0537	2-Cyano-N,N-dimethylacetamide	MDA-MB-231	C29(0.82)	LDD2130	[1]
LDCM0524	2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide	MDA-MB-231	C29(0.77)	LDD2117	[1]
LDCM0558	2-Cyano-N-phenylacetamide	MDA-MB-231	C29(1.11)	LDD2152	[1]
LDCM0539	3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile	MDA-MB-231	C29(0.44)	LDD2132	[1]
LDCM0538	4-(Cyanoacetyl)morpholine	MDA-MB-231	C29(0.49)	LDD2131	[1]
LDCM0214	AC1	HCT 116	C29(1.26)	LDD0531	[3]
LDCM0215	AC10	HCT 116	C62(1.09)	LDD0532	[3]
LDCM0216	AC100	HEK-293T	C29(1.39)	LDD0814	[3]
LDCM0217	AC101	HEK-293T	C29(0.72)	LDD0815	[3]
LDCM0218	AC102	HEK-293T	C29(0.62)	LDD0816	[3]
LDCM0219	AC103	HEK-293T	C29(0.92)	LDD0817	[3]
LDCM0220	AC104	HEK-293T	C29(0.86)	LDD0818	[3]
LDCM0221	AC105	HEK-293T	C29(0.80)	LDD0819	[3]
LDCM0222	AC106	HEK-293T	C29(0.66)	LDD0820	[3]
LDCM0223	AC107	HEK-293T	C29(1.05)	LDD0821	[3]
LDCM0224	AC108	HEK-293T	C29(0.54)	LDD0822	[3]
LDCM0225	AC109	HEK-293T	C29(0.79)	LDD0823	[3]
LDCM0226	AC11	HCT 116	C62(1.09)	LDD0543	[3]
LDCM0227	AC110	HEK-293T	C29(1.33)	LDD0825	[3]
LDCM0228	AC111	HEK-293T	C29(1.32)	LDD0826	[3]
LDCM0229	AC112	HEK-293T	C29(1.59)	LDD0827	[3]
LDCM0230	AC113	HCT 116	C29(1.25)	LDD0547	[3]
LDCM0231	AC114	HCT 116	C29(0.99)	LDD0548	[3]
LDCM0232	AC115	HCT 116	C29(0.94)	LDD0549	[3]
LDCM0233	AC116	HCT 116	C29(0.87)	LDD0550	[3]
LDCM0234	AC117	HCT 116	C29(1.07)	LDD0551	[3]
LDCM0235	AC118	HCT 116	C29(1.09)	LDD0552	[3]
LDCM0236	AC119	HCT 116	C29(0.98)	LDD0553	[3]
LDCM0237	AC12	HCT 116	C62(1.18)	LDD0554	[3]
LDCM0238	AC120	HCT 116	C29(1.00)	LDD0555	[3]
LDCM0239	AC121	HCT 116	C29(1.14)	LDD0556	[3]
LDCM0240	AC122	HCT 116	C29(0.83)	LDD0557	[3]
LDCM0241	AC123	HCT 116	C29(1.25)	LDD0558	[3]
LDCM0242	AC124	HCT 116	C29(0.94)	LDD0559	[3]
LDCM0243	AC125	HCT 116	C29(1.11)	LDD0560	[3]
LDCM0244	AC126	HCT 116	C29(0.87)	LDD0561	[3]
LDCM0245	AC127	HCT 116	C29(0.85)	LDD0562	[3]
LDCM0246	AC128	HCT 116	C62(1.03)	LDD0563	[3]
LDCM0247	AC129	HCT 116	C62(0.80)	LDD0564	[3]
LDCM0249	AC130	HCT 116	C62(0.91)	LDD0566	[3]
LDCM0250	AC131	HCT 116	C62(1.03)	LDD0567	[3]
LDCM0251	AC132	HCT 116	C62(0.98)	LDD0568	[3]
LDCM0252	AC133	HCT 116	C62(0.98)	LDD0569	[3]
LDCM0253	AC134	HCT 116	C62(1.00)	LDD0570	[3]
LDCM0254	AC135	HCT 116	C62(1.03)	LDD0571	[3]
LDCM0255	AC136	HCT 116	C62(0.95)	LDD0572	[3]
LDCM0256	AC137	HCT 116	C62(0.97)	LDD0573	[3]
LDCM0257	AC138	HCT 116	C62(0.88)	LDD0574	[3]
LDCM0258	AC139	HCT 116	C62(0.95)	LDD0575	[3]
LDCM0259	AC14	HCT 116	C62(1.07)	LDD0576	[3]
LDCM0260	AC140	HCT 116	C62(0.94)	LDD0577	[3]
LDCM0261	AC141	HCT 116	C62(0.97)	LDD0578	[3]
LDCM0262	AC142	HCT 116	C62(0.85)	LDD0579	[3]
LDCM0263	AC143	HCT 116	C29(0.84)	LDD0580	[3]
LDCM0264	AC144	HCT 116	C29(0.53)	LDD0581	[3]
LDCM0265	AC145	HCT 116	C29(0.65)	LDD0582	[3]
LDCM0266	AC146	HCT 116	C29(0.50)	LDD0583	[3]
LDCM0267	AC147	HCT 116	C29(0.51)	LDD0584	[3]
LDCM0268	AC148	HCT 116	C29(0.56)	LDD0585	[3]
LDCM0269	AC149	HCT 116	C29(0.51)	LDD0586	[3]
LDCM0270	AC15	HCT 116	C62(0.83)	LDD0587	[3]
LDCM0271	AC150	HCT 116	C29(0.64)	LDD0588	[3]
LDCM0272	AC151	HCT 116	C29(0.65)	LDD0589	[3]
LDCM0273	AC152	HCT 116	C29(0.52)	LDD0590	[3]
LDCM0274	AC153	HCT 116	C29(0.56)	LDD0591	[3]
LDCM0621	AC154	HCT 116	C29(0.49)	LDD2158	[3]
LDCM0622	AC155	HCT 116	C29(0.48)	LDD2159	[3]
LDCM0623	AC156	HCT 116	C29(0.72)	LDD2160	[3]
LDCM0624	AC157	HCT 116	C29(0.73)	LDD2161	[3]
LDCM0276	AC17	HEK-293T	C29(1.09)	LDD0874	[3]
LDCM0277	AC18	HEK-293T	C29(1.04)	LDD0875	[3]
LDCM0278	AC19	HEK-293T	C29(1.01)	LDD0876	[3]
LDCM0279	AC2	HCT 116	C29(1.02)	LDD0596	[3]
LDCM0280	AC20	HEK-293T	C29(1.11)	LDD0878	[3]
LDCM0281	AC21	HEK-293T	C29(1.28)	LDD0879	[3]
LDCM0282	AC22	HEK-293T	C29(1.14)	LDD0880	[3]
LDCM0283	AC23	HEK-293T	C29(1.33)	LDD0881	[3]
LDCM0284	AC24	HEK-293T	C29(1.02)	LDD0882	[3]
LDCM0285	AC25	HCT 116	C29(0.79)	LDD0602	[3]
LDCM0286	AC26	HCT 116	C29(0.66)	LDD0603	[3]
LDCM0287	AC27	HCT 116	C29(0.82)	LDD0604	[3]
LDCM0288	AC28	HCT 116	C29(0.72)	LDD0605	[3]
LDCM0289	AC29	HCT 116	C29(0.84)	LDD0606	[3]
LDCM0290	AC3	HCT 116	C29(1.37)	LDD0607	[3]
LDCM0291	AC30	HCT 116	C29(0.75)	LDD0608	[3]
LDCM0292	AC31	HCT 116	C29(0.80)	LDD0609	[3]
LDCM0293	AC32	HCT 116	C29(0.58)	LDD0610	[3]
LDCM0294	AC33	HCT 116	C29(0.65)	LDD0611	[3]
LDCM0295	AC34	HCT 116	C29(0.66)	LDD0612	[3]
LDCM0296	AC35	HCT 116	C29(1.21)	LDD0613	[3]
LDCM0297	AC36	HCT 116	C29(1.14)	LDD0614	[3]
LDCM0298	AC37	HCT 116	C29(1.25)	LDD0615	[3]
LDCM0299	AC38	HCT 116	C29(1.06)	LDD0616	[3]
LDCM0300	AC39	HCT 116	C29(1.05)	LDD0617	[3]
LDCM0301	AC4	HCT 116	C29(0.96)	LDD0618	[3]
LDCM0302	AC40	HCT 116	C29(1.00)	LDD0619	[3]
LDCM0303	AC41	HCT 116	C29(1.32)	LDD0620	[3]
LDCM0304	AC42	HCT 116	C29(0.89)	LDD0621	[3]
LDCM0305	AC43	HCT 116	C29(1.06)	LDD0622	[3]
LDCM0306	AC44	HCT 116	C29(0.96)	LDD0623	[3]
LDCM0307	AC45	HCT 116	C29(1.09)	LDD0624	[3]
LDCM0308	AC46	HCT 116	C29(1.06)	LDD0625	[3]
LDCM0309	AC47	HCT 116	C29(1.02)	LDD0626	[3]
LDCM0310	AC48	HCT 116	C29(1.12)	LDD0627	[3]
LDCM0311	AC49	HCT 116	C29(1.07)	LDD0628	[3]
LDCM0312	AC5	HCT 116	C29(1.24)	LDD0629	[3]
LDCM0313	AC50	HCT 116	C29(1.04)	LDD0630	[3]
LDCM0314	AC51	HCT 116	C29(1.32)	LDD0631	[3]
LDCM0315	AC52	HCT 116	C29(1.20)	LDD0632	[3]
LDCM0316	AC53	HCT 116	C29(0.92)	LDD0633	[3]
LDCM0317	AC54	HCT 116	C29(0.98)	LDD0634	[3]
LDCM0318	AC55	HCT 116	C29(1.00)	LDD0635	[3]
LDCM0319	AC56	HCT 116	C29(1.06)	LDD0636	[3]
LDCM0320	AC57	HEK-293T	C29(0.77)	LDD0918	[3]
LDCM0321	AC58	HEK-293T	C29(0.73)	LDD0919	[3]
LDCM0322	AC59	HEK-293T	C29(0.60)	LDD0920	[3]
LDCM0323	AC6	HCT 116	C62(0.96)	LDD0640	[3]
LDCM0324	AC60	HEK-293T	C29(1.65)	LDD0922	[3]
LDCM0325	AC61	HEK-293T	C29(0.70)	LDD0923	[3]
LDCM0326	AC62	HEK-293T	C29(0.57)	LDD0924	[3]
LDCM0327	AC63	HEK-293T	C29(0.55)	LDD0925	[3]
LDCM0328	AC64	HEK-293T	C29(0.65)	LDD0926	[3]
LDCM0329	AC65	HEK-293T	C29(0.69)	LDD0927	[3]
LDCM0330	AC66	HEK-293T	C29(0.61)	LDD0928	[3]
LDCM0331	AC67	HEK-293T	C29(0.57)	LDD0929	[3]
LDCM0332	AC68	HCT 116	C29(1.10)	LDD0649	[3]
LDCM0333	AC69	HCT 116	C29(0.96)	LDD0650	[3]
LDCM0334	AC7	HCT 116	C62(0.80)	LDD0651	[3]
LDCM0335	AC70	HCT 116	C29(1.08)	LDD0652	[3]
LDCM0336	AC71	HCT 116	C29(1.04)	LDD0653	[3]
LDCM0337	AC72	HCT 116	C29(1.05)	LDD0654	[3]
LDCM0338	AC73	HCT 116	C29(0.98)	LDD0655	[3]
LDCM0339	AC74	HCT 116	C29(1.08)	LDD0656	[3]
LDCM0340	AC75	HCT 116	C29(1.02)	LDD0657	[3]
LDCM0341	AC76	HCT 116	C29(1.15)	LDD0658	[3]
LDCM0342	AC77	HCT 116	C29(0.94)	LDD0659	[3]
LDCM0343	AC78	HCT 116	C29(1.10)	LDD0660	[3]
LDCM0344	AC79	HCT 116	C29(1.15)	LDD0661	[3]
LDCM0345	AC8	HCT 116	C62(1.23)	LDD0662	[3]
LDCM0346	AC80	HCT 116	C29(1.08)	LDD0663	[3]
LDCM0347	AC81	HCT 116	C29(1.25)	LDD0664	[3]
LDCM0348	AC82	HCT 116	C29(1.05)	LDD0665	[3]
LDCM0349	AC83	HCT 116	C29(0.64)	LDD0666	[3]
LDCM0350	AC84	HCT 116	C29(0.70)	LDD0667	[3]
LDCM0351	AC85	HCT 116	C29(0.67)	LDD0668	[3]
LDCM0352	AC86	HCT 116	C29(0.71)	LDD0669	[3]
LDCM0353	AC87	HCT 116	C29(0.83)	LDD0670	[3]
LDCM0354	AC88	HCT 116	C29(0.72)	LDD0671	[3]
LDCM0355	AC89	HCT 116	C29(0.66)	LDD0672	[3]
LDCM0357	AC90	HCT 116	C29(1.01)	LDD0674	[3]
LDCM0358	AC91	HCT 116	C29(0.67)	LDD0675	[3]
LDCM0359	AC92	HCT 116	C29(0.70)	LDD0676	[3]
LDCM0360	AC93	HCT 116	C29(0.80)	LDD0677	[3]
LDCM0361	AC94	HCT 116	C29(0.59)	LDD0678	[3]
LDCM0362	AC95	HCT 116	C29(0.77)	LDD0679	[3]
LDCM0363	AC96	HCT 116	C29(0.53)	LDD0680	[3]
LDCM0364	AC97	HCT 116	C29(0.65)	LDD0681	[3]
LDCM0365	AC98	HEK-293T	C29(0.78)	LDD0963	[3]
LDCM0366	AC99	HEK-293T	C29(0.53)	LDD0964	[3]
LDCM0545	Acetamide	MDA-MB-231	C29(0.29)	LDD2138	[1]
LDCM0520	AKOS000195272	MDA-MB-231	C29(0.91)	LDD2113	[1]
LDCM0248	AKOS034007472	HCT 116	C62(1.11)	LDD0565	[3]
LDCM0356	AKOS034007680	HCT 116	C62(1.30)	LDD0673	[3]
LDCM0275	AKOS034007705	HCT 116	C62(0.82)	LDD0592	[3]
LDCM0108	Chloroacetamide	HeLa	H90(0.00); C29(0.00)	LDD0222	[8]
LDCM0367	CL1	HCT 116	C62(1.63)	LDD0684	[3]
LDCM0368	CL10	HCT 116	C62(0.66)	LDD0685	[3]
LDCM0369	CL100	HCT 116	C29(1.12)	LDD0686	[3]
LDCM0370	CL101	HCT 116	C62(0.91)	LDD0687	[3]
LDCM0371	CL102	HCT 116	C62(1.06)	LDD0688	[3]
LDCM0372	CL103	HCT 116	C62(1.43)	LDD0689	[3]
LDCM0373	CL104	HCT 116	C62(1.16)	LDD0690	[3]
LDCM0374	CL105	HEK-293T	C29(1.01)	LDD0972	[3]
LDCM0375	CL106	HEK-293T	C29(1.06)	LDD0973	[3]
LDCM0376	CL107	HEK-293T	C29(1.13)	LDD0974	[3]
LDCM0377	CL108	HEK-293T	C29(0.96)	LDD0975	[3]
LDCM0378	CL109	HEK-293T	C29(0.98)	LDD0976	[3]
LDCM0379	CL11	HCT 116	C62(0.79)	LDD0696	[3]
LDCM0380	CL110	HEK-293T	C29(0.94)	LDD0978	[3]
LDCM0381	CL111	HEK-293T	C29(0.91)	LDD0979	[3]
LDCM0382	CL112	HCT 116	C29(1.05)	LDD0699	[3]
LDCM0383	CL113	HCT 116	C29(0.64)	LDD0700	[3]
LDCM0384	CL114	HCT 116	C29(0.88)	LDD0701	[3]
LDCM0385	CL115	HCT 116	C29(0.66)	LDD0702	[3]
LDCM0386	CL116	HCT 116	C29(0.74)	LDD0703	[3]
LDCM0387	CL117	HCT 116	C29(1.07)	LDD0704	[3]
LDCM0388	CL118	HCT 116	C29(1.19)	LDD0705	[3]
LDCM0389	CL119	HCT 116	C29(1.12)	LDD0706	[3]
LDCM0390	CL12	HCT 116	C62(0.88)	LDD0707	[3]
LDCM0391	CL120	HCT 116	C29(1.17)	LDD0708	[3]
LDCM0392	CL121	HCT 116	C29(0.67)	LDD0709	[3]
LDCM0393	CL122	HCT 116	C29(1.00)	LDD0710	[3]
LDCM0394	CL123	HCT 116	C29(0.95)	LDD0711	[3]
LDCM0395	CL124	HCT 116	C29(0.92)	LDD0712	[3]
LDCM0396	CL125	HEK-293T	C29(0.82)	LDD0994	[3]
LDCM0397	CL126	HEK-293T	C29(0.60)	LDD0995	[3]
LDCM0398	CL127	HEK-293T	C29(0.67)	LDD0996	[3]
LDCM0399	CL128	HEK-293T	C29(0.63)	LDD0997	[3]
LDCM0400	CL13	HCT 116	C62(0.80)	LDD0717	[3]
LDCM0401	CL14	HCT 116	C62(1.10)	LDD0718	[3]
LDCM0402	CL15	HCT 116	C62(0.77)	LDD0719	[3]
LDCM0403	CL16	HEK-293T	C29(0.95)	LDD1001	[3]
LDCM0404	CL17	HEK-293T	C29(0.89)	LDD1002	[3]
LDCM0405	CL18	HEK-293T	C29(1.02)	LDD1003	[3]
LDCM0406	CL19	HEK-293T	C29(0.98)	LDD1004	[3]
LDCM0407	CL2	HCT 116	C62(1.43)	LDD0724	[3]
LDCM0408	CL20	HEK-293T	C29(0.95)	LDD1006	[3]
LDCM0409	CL21	HEK-293T	C29(1.02)	LDD1007	[3]
LDCM0410	CL22	HEK-293T	C29(1.03)	LDD1008	[3]
LDCM0411	CL23	HEK-293T	C29(0.97)	LDD1009	[3]
LDCM0412	CL24	HEK-293T	C29(0.98)	LDD1010	[3]
LDCM0413	CL25	HEK-293T	C29(0.97)	LDD1011	[3]
LDCM0414	CL26	HEK-293T	C29(1.10)	LDD1012	[3]
LDCM0415	CL27	HEK-293T	C29(1.04)	LDD1013	[3]
LDCM0416	CL28	HEK-293T	C29(0.88)	LDD1014	[3]
LDCM0417	CL29	HEK-293T	C29(1.01)	LDD1015	[3]
LDCM0418	CL3	HCT 116	C62(1.06)	LDD0735	[3]
LDCM0419	CL30	HEK-293T	C29(1.29)	LDD1017	[3]
LDCM0420	CL31	HCT 116	C62(0.84)	LDD0737	[3]
LDCM0421	CL32	HCT 116	C62(0.82)	LDD0738	[3]
LDCM0422	CL33	HCT 116	C62(0.73)	LDD0739	[3]
LDCM0423	CL34	HCT 116	C62(0.72)	LDD0740	[3]
LDCM0424	CL35	HCT 116	C62(0.96)	LDD0741	[3]
LDCM0425	CL36	HCT 116	C62(0.81)	LDD0742	[3]
LDCM0426	CL37	HCT 116	C62(0.82)	LDD0743	[3]
LDCM0428	CL39	HCT 116	C62(0.76)	LDD0745	[3]
LDCM0429	CL4	HCT 116	C62(1.40)	LDD0746	[3]
LDCM0430	CL40	HCT 116	C62(0.71)	LDD0747	[3]
LDCM0431	CL41	HCT 116	C62(0.74)	LDD0748	[3]
LDCM0432	CL42	HCT 116	C62(0.57)	LDD0749	[3]
LDCM0433	CL43	HCT 116	C62(0.83)	LDD0750	[3]
LDCM0434	CL44	HCT 116	C62(0.67)	LDD0751	[3]
LDCM0435	CL45	HCT 116	C62(0.66)	LDD0752	[3]
LDCM0436	CL46	HCT 116	C62(1.28)	LDD0753	[3]
LDCM0437	CL47	HCT 116	C62(1.01)	LDD0754	[3]
LDCM0438	CL48	HCT 116	C62(1.46)	LDD0755	[3]
LDCM0439	CL49	HCT 116	C62(2.17)	LDD0756	[3]
LDCM0440	CL5	HCT 116	C62(1.16)	LDD0757	[3]
LDCM0441	CL50	HCT 116	C62(1.94)	LDD0758	[3]
LDCM0442	CL51	HCT 116	C62(1.13)	LDD0759	[3]
LDCM0443	CL52	HCT 116	C62(1.13)	LDD0760	[3]
LDCM0444	CL53	HCT 116	C62(1.51)	LDD0761	[3]
LDCM0445	CL54	HCT 116	C62(1.25)	LDD0762	[3]
LDCM0446	CL55	HCT 116	C62(1.49)	LDD0763	[3]
LDCM0447	CL56	HCT 116	C62(1.06)	LDD0764	[3]
LDCM0448	CL57	HCT 116	C62(1.33)	LDD0765	[3]
LDCM0449	CL58	HCT 116	C62(1.09)	LDD0766	[3]
LDCM0450	CL59	HCT 116	C62(1.21)	LDD0767	[3]
LDCM0451	CL6	HCT 116	C62(0.76)	LDD0768	[3]
LDCM0452	CL60	HCT 116	C62(1.52)	LDD0769	[3]
LDCM0453	CL61	HEK-293T	C29(0.87)	LDD1051	[3]
LDCM0454	CL62	HEK-293T	C29(1.07)	LDD1052	[3]
LDCM0455	CL63	HEK-293T	C29(1.02)	LDD1053	[3]
LDCM0456	CL64	HEK-293T	C29(0.95)	LDD1054	[3]
LDCM0457	CL65	HEK-293T	C29(1.13)	LDD1055	[3]
LDCM0458	CL66	HEK-293T	C29(1.04)	LDD1056	[3]
LDCM0459	CL67	HEK-293T	C29(1.21)	LDD1057	[3]
LDCM0460	CL68	HEK-293T	C29(1.02)	LDD1058	[3]
LDCM0461	CL69	HEK-293T	C29(1.08)	LDD1059	[3]
LDCM0462	CL7	HCT 116	C62(0.99)	LDD0779	[3]
LDCM0463	CL70	HEK-293T	C29(0.97)	LDD1061	[3]
LDCM0464	CL71	HEK-293T	C29(1.03)	LDD1062	[3]
LDCM0465	CL72	HEK-293T	C29(0.99)	LDD1063	[3]
LDCM0466	CL73	HEK-293T	C29(1.39)	LDD1064	[3]
LDCM0467	CL74	HEK-293T	C29(1.43)	LDD1065	[3]
LDCM0469	CL76	HCT 116	C29(0.81)	LDD0786	[3]
LDCM0470	CL77	HCT 116	C29(0.87)	LDD0787	[3]
LDCM0471	CL78	HCT 116	C29(0.88)	LDD0788	[3]
LDCM0472	CL79	HCT 116	C29(0.74)	LDD0789	[3]
LDCM0473	CL8	HCT 116	C62(0.72)	LDD0790	[3]
LDCM0474	CL80	HCT 116	C29(0.82)	LDD0791	[3]
LDCM0475	CL81	HCT 116	C29(0.85)	LDD0792	[3]
LDCM0476	CL82	HCT 116	C29(0.71)	LDD0793	[3]
LDCM0477	CL83	HCT 116	C29(0.83)	LDD0794	[3]
LDCM0478	CL84	HCT 116	C29(0.86)	LDD0795	[3]
LDCM0479	CL85	HCT 116	C29(0.86)	LDD0796	[3]
LDCM0480	CL86	HCT 116	C29(1.05)	LDD0797	[3]
LDCM0481	CL87	HCT 116	C29(0.74)	LDD0798	[3]
LDCM0482	CL88	HCT 116	C29(0.78)	LDD0799	[3]
LDCM0483	CL89	HCT 116	C29(0.86)	LDD0800	[3]
LDCM0484	CL9	HCT 116	C62(0.90)	LDD0801	[3]
LDCM0485	CL90	HCT 116	C29(1.26)	LDD0802	[3]
LDCM0486	CL91	HCT 116	C29(1.13)	LDD0803	[3]
LDCM0487	CL92	HCT 116	C29(1.29)	LDD0804	[3]
LDCM0488	CL93	HCT 116	C29(1.35)	LDD0805	[3]
LDCM0489	CL94	HCT 116	C29(0.97)	LDD0806	[3]
LDCM0490	CL95	HCT 116	C29(0.98)	LDD0807	[3]
LDCM0491	CL96	HCT 116	C29(1.03)	LDD0808	[3]
LDCM0492	CL97	HCT 116	C29(1.12)	LDD0809	[3]
LDCM0493	CL98	HCT 116	C29(1.11)	LDD0810	[3]
LDCM0494	CL99	HCT 116	C29(1.09)	LDD0811	[3]
LDCM0495	E2913	HEK-293T	C29(0.83); C62(0.95)	LDD1698	[14]
LDCM0213	Electrophilic fragment 2	MDA-MB-231	C29(64.48)	LDD1702	[1]
LDCM0625	F8	Ramos	C29(2.28); C62(0.53)	LDD2187	[15]
LDCM0572	Fragment10	Ramos	C29(7.46)	LDD2189	[15]
LDCM0573	Fragment11	Ramos	C29(0.03)	LDD2190	[15]
LDCM0574	Fragment12	Ramos	C29(15.84)	LDD2191	[15]
LDCM0575	Fragment13	Ramos	C29(1.57); C62(0.34)	LDD2192	[15]
LDCM0576	Fragment14	Ramos	C29(20.00)	LDD2193	[15]
LDCM0579	Fragment20	Ramos	C29(20.00)	LDD2194	[15]
LDCM0580	Fragment21	Ramos	C29(1.55)	LDD2195	[15]
LDCM0582	Fragment23	Ramos	C29(0.87)	LDD2196	[15]
LDCM0578	Fragment27	Ramos	C29(0.93); C62(0.36)	LDD2197	[15]
LDCM0586	Fragment28	Ramos	C29(1.07); C62(0.38)	LDD2198	[15]
LDCM0588	Fragment30	Ramos	C29(2.27); C62(0.18)	LDD2199	[15]
LDCM0589	Fragment31	Ramos	C29(1.82)	LDD2200	[15]
LDCM0590	Fragment32	Ramos	C29(10.43)	LDD2201	[15]
LDCM0468	Fragment33	HEK-293T	C29(1.15)	LDD1066	[3]
LDCM0596	Fragment38	Ramos	C29(10.37); C62(0.74)	LDD2203	[15]
LDCM0566	Fragment4	Ramos	C29(11.41); C62(0.74)	LDD2184	[15]
LDCM0427	Fragment51	HCT 116	C62(0.76)	LDD0744	[3]
LDCM0610	Fragment52	Ramos	C29(3.12)	LDD2204	[15]
LDCM0614	Fragment56	Ramos	C29(1.53); C62(0.54)	LDD2205	[15]
LDCM0569	Fragment7	Ramos	C29(11.46)	LDD2186	[15]
LDCM0571	Fragment9	Ramos	C29(20.00)	LDD2188	[15]
LDCM0015	HNE	MDA-MB-231	C29(2.34); C62(1.12)	LDD0346	[15]
LDCM0107	IAA	HeLa	H90(0.00); C29(0.00)	LDD0221	[8]
LDCM0022	KB02	HEK-293T	C29(0.93); C62(1.08)	LDD1492	[14]
LDCM0023	KB03	HEK-293T	C29(0.99); C62(1.07)	LDD1497	[14]
LDCM0024	KB05	COLO792	C62(2.20)	LDD3310	[16]
LDCM0509	N-(4-bromo-3,5-dimethylphenyl)-2-nitroacetamide	MDA-MB-231	C29(1.26)	LDD2102	[1]
LDCM0528	N-(4-bromophenyl)-2-cyano-N-phenylacetamide	MDA-MB-231	C29(0.68)	LDD2121	[1]
LDCM0109	NEM	HeLa	N.A.	LDD0223	[8]
LDCM0496	Nucleophilic fragment 11a	MDA-MB-231	C29(0.80)	LDD2089	[1]
LDCM0497	Nucleophilic fragment 11b	MDA-MB-231	C29(1.27)	LDD2090	[1]
LDCM0499	Nucleophilic fragment 12b	MDA-MB-231	C29(0.95)	LDD2092	[1]
LDCM0500	Nucleophilic fragment 13a	MDA-MB-231	C29(0.96)	LDD2093	[1]
LDCM0503	Nucleophilic fragment 14b	MDA-MB-231	C29(0.86)	LDD2096	[1]
LDCM0504	Nucleophilic fragment 15a	MDA-MB-231	C29(1.02)	LDD2097	[1]
LDCM0506	Nucleophilic fragment 16a	MDA-MB-231	C29(0.79)	LDD2099	[1]
LDCM0507	Nucleophilic fragment 16b	MDA-MB-231	C29(2.00)	LDD2100	[1]
LDCM0508	Nucleophilic fragment 17a	MDA-MB-231	C29(1.19)	LDD2101	[1]
LDCM0511	Nucleophilic fragment 18b	MDA-MB-231	C29(1.15)	LDD2104	[1]
LDCM0512	Nucleophilic fragment 19a	MDA-MB-231	C29(1.12)	LDD2105	[1]
LDCM0513	Nucleophilic fragment 19b	MDA-MB-231	C29(1.08)	LDD2106	[1]
LDCM0514	Nucleophilic fragment 20a	MDA-MB-231	C29(0.79)	LDD2107	[1]
LDCM0515	Nucleophilic fragment 20b	MDA-MB-231	C29(0.89)	LDD2108	[1]
LDCM0516	Nucleophilic fragment 21a	MDA-MB-231	C29(0.85)	LDD2109	[1]
LDCM0517	Nucleophilic fragment 21b	MDA-MB-231	C29(1.93)	LDD2110	[1]
LDCM0518	Nucleophilic fragment 22a	MDA-MB-231	C29(0.94)	LDD2111	[1]
LDCM0521	Nucleophilic fragment 23b	MDA-MB-231	C29(1.02)	LDD2114	[1]
LDCM0522	Nucleophilic fragment 24a	MDA-MB-231	C29(0.57)	LDD2115	[1]
LDCM0523	Nucleophilic fragment 24b	MDA-MB-231	C29(0.80)	LDD2116	[1]
LDCM0525	Nucleophilic fragment 25b	MDA-MB-231	C29(1.00)	LDD2118	[1]
LDCM0526	Nucleophilic fragment 26a	MDA-MB-231	C29(2.18)	LDD2119	[1]
LDCM0527	Nucleophilic fragment 26b	MDA-MB-231	C29(0.84)	LDD2120	[1]
LDCM0529	Nucleophilic fragment 27b	MDA-MB-231	C29(0.89)	LDD2122	[1]
LDCM0530	Nucleophilic fragment 28a	MDA-MB-231	C29(0.83)	LDD2123	[1]
LDCM0531	Nucleophilic fragment 28b	MDA-MB-231	C29(0.99)	LDD2124	[1]
LDCM0532	Nucleophilic fragment 29a	MDA-MB-231	C29(0.68)	LDD2125	[1]
LDCM0533	Nucleophilic fragment 29b	MDA-MB-231	C29(1.01)	LDD2126	[1]
LDCM0534	Nucleophilic fragment 30a	MDA-MB-231	C29(1.10)	LDD2127	[1]
LDCM0535	Nucleophilic fragment 30b	MDA-MB-231	C29(1.07)	LDD2128	[1]
LDCM0536	Nucleophilic fragment 31	MDA-MB-231	C29(0.79)	LDD2129	[1]
LDCM0540	Nucleophilic fragment 35	MDA-MB-231	C29(0.66)	LDD2133	[1]
LDCM0541	Nucleophilic fragment 36	MDA-MB-231	C29(0.56)	LDD2134	[1]
LDCM0542	Nucleophilic fragment 37	MDA-MB-231	C29(0.93)	LDD2135	[1]
LDCM0543	Nucleophilic fragment 38	MDA-MB-231	C29(1.38)	LDD2136	[1]
LDCM0544	Nucleophilic fragment 39	MDA-MB-231	C29(0.89)	LDD2137	[1]
LDCM0211	Nucleophilic fragment 3b	MDA-MB-231	C29(1.27)	LDD1700	[1]
LDCM0546	Nucleophilic fragment 40	MDA-MB-231	C29(0.69)	LDD2140	[1]
LDCM0547	Nucleophilic fragment 41	MDA-MB-231	C29(0.89)	LDD2141	[1]
LDCM0549	Nucleophilic fragment 43	MDA-MB-231	C29(1.19)	LDD2143	[1]
LDCM0550	Nucleophilic fragment 5a	MDA-MB-231	C29(2.67)	LDD2144	[1]
LDCM0551	Nucleophilic fragment 5b	MDA-MB-231	C29(6.93)	LDD2145	[1]
LDCM0552	Nucleophilic fragment 6a	MDA-MB-231	C29(0.82)	LDD2146	[1]
LDCM0553	Nucleophilic fragment 6b	MDA-MB-231	C29(2.49)	LDD2147	[1]
LDCM0554	Nucleophilic fragment 7a	MDA-MB-231	C29(0.58)	LDD2148	[1]
LDCM0555	Nucleophilic fragment 7b	MDA-MB-231	C29(1.11)	LDD2149	[1]
LDCM0556	Nucleophilic fragment 8a	MDA-MB-231	C29(0.44)	LDD2150	[1]
LDCM0557	Nucleophilic fragment 8b	MDA-MB-231	C29(0.98)	LDD2151	[1]
LDCM0627	NUDT7-COV-1	HEK-293T	C29(0.51)	LDD2206	[17]
LDCM0131	RA190	MM1.R	C62(1.47)	LDD0304	[18]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other

Click To Hide/Show 3 Protein(s) Interacting with This Target

Protein name	Family	Uniprot ID
Keratin, type I cuticular Ha4 (KRT34)	Intermediate filament family	O76011
Disks large homolog 2 (DLG2)	MAGUK family	Q15700
Disks large homolog 3 (DLG3)	MAGUK family	Q92796

References

1	Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29. Mass spectrometry data entry: PXD039908 , PXD029761
2	An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
3	Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
4	Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling. Nat Chem. 2024 Jun 4. doi: 10.1038/s41557-024-01545-6. Online ahead of print. Mass spectrometry data entry: PXD042377
5	Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23. Mass spectrometry data entry: PXD028853
6	Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24. Mass spectrometry data entry: PXD029255
7	Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20. Mass spectrometry data entry: PXD022279
8	ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
9	Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
10	Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26. Mass spectrometry data entry: PXD041587
11	Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
12	Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.
13	Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. ACS Chem Biol. 2017 Oct 20;12(10):2671-2681. doi: 10.1021/acschembio.7b00581. Epub 2017 Sep 20. Mass spectrometry data entry: PXD007570
14	Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19. Mass spectrometry data entry: PXD044402
15	Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7. Mass spectrometry data entry: PXD027578
16	DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22. Mass spectrometry data entry: PXD047840
17	Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.
18	Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.

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Correspondence

Prof. Feng Zhu

Prof. Feng Ni