Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C102 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP06618 | ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) | 11.8 | ||||
| LDTP12886 | Glycerophosphodiester phosphodiesterase 1 (GDE1) | 9.1 | ||||
| LDTP04004 | Lysosomal Pro-X carboxypeptidase (PRCP) | 8.1 | ||||
| LDTP08476 | 5'-3' exonuclease PLD3 (PLD3) | 7.9 | ||||
| LDTP12363 | Lysophosphatidic acid phosphatase type 6 (ACP6) | 7.4 | ||||
| LDTP04712 | Puromycin-sensitive aminopeptidase (NPEPPS) | 7.2 | ||||
| LDTP06333 | Serum paraoxonase/arylesterase 2 (PON2) | 6.2 | ||||
| LDTP11336 | Chitinase domain-containing protein 1 (CHID1) | 6.1 | ||||
| LDTP13282 | Prenylcysteine oxidase 1 (PCYOX1) | 5.9 | ||||
| LDTP12013 | dCTP pyrophosphatase 1 (DCTPP1) | 5.9 | ||||
| LDTP02150 | ATP synthase subunit beta, mitochondrial (ATP5F1B) | 5.9 | ||||
| LDTP00697 | Cytochrome b5 type B (CYB5B) | 5.5 | ||||
| LDTP12197 | Ethanolamine kinase 1 (ETNK1) | 5.2 | ||||
| LDTP01982 | NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) | 5.0 | ||||
| LDTP01803 | Adenosine deaminase (ADA) | 5.0 | ||||
| LDTP04211 | Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) | 4.9 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 21.9 | ||||
| LDTP14952 | Mpv17-like protein 2 (MPV17L2) | 11.5 | ||||
| LDTP10958 | Sigma non-opioid intracellular receptor 1 (SIGMAR1) | 9.3 | ||||
| LDTP07667 | Transmembrane protein 205 (TMEM205) | 6.5 | ||||
| LDTP05900 | Metaxin-1 (MTX1) | 6.1 | ||||
| LDTP01217 | Metaxin-2 (MTX2) | 5.7 | ||||
| LDTP10913 | Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) | 5.5 | ||||
| LDTP03277 | ER lumen protein-retaining receptor 1 (KDELR1) | 5.5 | ||||
| LDTP17641 | Solute carrier family 35 member F2 (SLC35F2) | 5.1 | ||||
| LDTP00865 | Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) | 5.1 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP15623 | Neuferricin (CYB5D2) | 14.3 | ||||
| LDTP11143 | Centromere protein K (CENPK) | 10.1 | ||||
| LDTP15714 | Mdm2-binding protein (MTBP) | 8.9 | ||||
| LDTP13630 | Neudesin (NENF) | 7.2 | ||||
| LDTP01608 | Proteasome assembly chaperone 1 (PSMG1) | 7.1 | ||||
| LDTP11076 | Apolipoprotein L2 (APOL2) | 7.0 | ||||
| LDTP14486 | Clustered mitochondria protein homolog (CLUH) | 6.7 | ||||
| LDTP00312 | U3 small nucleolar ribonucleoprotein protein MPP10 (MPHOSPH10) | 6.1 | ||||
| LDTP02124 | Keratin, type I cytoskeletal 18 (KRT18) | 5.9 | ||||
| LDTP06097 | Reticulocalbin-2 (RCN2) | 5.9 | ||||
| LDTP01652 | Centrosomal protein 43 (CEP43) | 5.6 | ||||
| LDTP04094 | Large proline-rich protein BAG6 (BAG6) | 5.4 | ||||
| LDTP13902 | Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (COA3) | 5.0 | ||||