Details of the Probe-central Interaction Altas

General Information of Experiment

Probe Name C187  Probe Info 
Probe concentration Probe:50uM; negative probe:50uM
Criteria Quantification: AfBPP Probe vs Negative Probe
Quantitative Method
TMT
In Vivo Experiment Model Model Type Living cell
Derived Tissue Peripheral blood
Disease Model Normal
Model Name Human normal cells (HEK-293T)
Note Negative probe:C#CCCC1(CCC(NC)=O)N=N1

Interaction Altas of This Experiment [1]

Enzyme
Click to Show/Hide to Show 135 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP13189  Cytochrome b-c1 complex subunit 9 (UQCR10) 99.7
 LDTP04565  Methionine aminopeptidase 1 (METAP1) 99.7
 LDTP04388  Palmitoyl-protein thioesterase 1 (PPT1) 99.7
 LDTP05006  Ras-related protein Rab-1A (RAB1A) 99.7
 LDTP03912  Trifunctional enzyme subunit alpha, mitochondrial (HADHA) 99.7
 LDTP05862  NAD(P) transhydrogenase, mitochondrial (NNT) 71.0
 LDTP05905  Acid ceramidase (ASAH1) 69.1
 LDTP10612  Lysophospholipid acyltransferase 7 (MBOAT7) 65.3
 LDTP07015  Alanine--tRNA ligase, mitochondrial (AARS2) 60.1
 LDTP00697  Cytochrome b5 type B (CYB5B) 59.3
 LDTP03842  Squalene synthase (FDFT1) 55.3
 LDTP09256  Putative phospholipase B-like 2 (PLBD2) 53.8
 LDTP12868  Endoplasmic reticulum aminopeptidase 1 (ERAP1) 51.6
 LDTP03394  Ceramide synthase 1 (CERS1) 50.9
 LDTP14030  V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) 50.9
 LDTP09666  Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) 48.5
 LDTP05624  Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) 47.5
 LDTP00428  Tripeptidyl-peptidase 1 (TPP1) 44.0
 LDTP11321  Acetyl-CoA acetyltransferase, cytosolic (ACAT2) 42.5
 LDTP03419  Proteasome subunit beta type-5 (PSMB5) 42.2
 LDTP05066  Signal peptidase complex catalytic subunit SEC11A (SEC11A) 42.2
 LDTP10215  Carboxymethylenebutenolidase homolog (CMBL) 41.1
 LDTP06787  Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) 40.2
 LDTP16032  Retinoid-inducible serine carboxypeptidase (SCPEP1) 38.3
 LDTP12691  Pyridoxine-5'-phosphate oxidase (PNPO) 37.8
 LDTP04618  Ubiquitin carboxyl-terminal hydrolase 14 (USP14) 37.5
 LDTP06648  Lanosterol 14-alpha demethylase (CYP51A1) 37.3
 LDTP10329  Ceramide synthase 2 (CERS2) 37.0
 LDTP02505  Lysosomal protective protein (CTSA) 36.5
 LDTP06477  Methylsterol monooxygenase 1 (MSMO1) 36.5
 LDTP00837  Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1) 36.3
 LDTP02359  Heme oxygenase 1 (HMOX1) 36.0
 LDTP10182  TLC domain-containing protein 1 (TLCD1) 35.3
 LDTP02254  ATP-dependent translocase ABCB1 (ABCB1) 33.1
 LDTP01241  Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) 33.1
 LDTP13282  Prenylcysteine oxidase 1 (PCYOX1) 33.1
 LDTP12253  Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) 32.2
 LDTP02342  Dihydropteridine reductase (QDPR) 32.0
 LDTP01039  Protein-S-isoprenylcysteine O-methyltransferase (ICMT) 31.1
 LDTP04581  Holocytochrome c-type synthase (HCCS) 29.9
 LDTP12279  Endoplasmic reticulum transmembrane helix translocase (ATP13A1) 28.2
 LDTP03540  Heme oxygenase 2 (HMOX2) 28.2
 LDTP12628  Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) 27.3
 LDTP05396  Histone-lysine N-methyltransferase 2A (KMT2A) 26.7
 LDTP17410  Cytochrome P450 20A1 (CYP20A1) 26.0
 LDTP01328  CAAX prenyl protease 1 homolog (ZMPSTE24) 25.8
 LDTP08476  5'-3' exonuclease PLD3 (PLD3) 25.6
 LDTP04437  Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) 25.1
 LDTP11127  ADP-dependent glucokinase (ADPGK) 24.9
 LDTP05758  S-methyl-5'-thioadenosine phosphorylase (MTAP) 24.8
 LDTP19745  ADP-ribosylation factor-like protein 10 (ARL10) 24.3
 LDTP07003  Presequence protease, mitochondrial (PITRM1) 24.3
 LDTP00877  Protein SCO2 homolog, mitochondrial (SCO2) 24.3
 LDTP10137  Cytochrome c oxidase assembly factor 7 (COA7) 24.1
 LDTP13504  Dermatan-sulfate epimerase (DSE) 24.1
 LDTP01462  Endonuclease domain-containing 1 protein (ENDOD1) 23.6
 LDTP02175  Epoxide hydrolase 1 (EPHX1) 23.4
 LDTP13620  Lysosomal thioesterase PPT2 (PPT2) 23.4
 LDTP09096  Carbohydrate sulfotransferase 14 (CHST14) 22.9
 LDTP02005  Lysosomal acid glucosylceramidase (GBA1) 22.9
 LDTP03417  Proteasome subunit beta type-4 (PSMB4) 22.9
 LDTP02837  Beta-galactosidase (GLB1) 22.8
 LDTP15422  Prostaglandin reductase 3 (PTGR3) 22.5
 LDTP04712  Puromycin-sensitive aminopeptidase (NPEPPS) 22.3
 LDTP06618  ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) 22.2
 LDTP14214  Dolichyl-phosphate beta-glucosyltransferase (ALG5) 21.9
 LDTP04285  Proteasome subunit beta type-2 (PSMB2) 21.9
 LDTP02141  Alpha-galactosidase A (GLA) 21.4
 LDTP04318  Glycogen synthase kinase-3 alpha (GSK3A) 21.4
 LDTP11874  Thioredoxin-related transmembrane protein 1 (TMX1) 21.3
 LDTP03822  Activin receptor type-1B (ACVR1B) 21.0
 LDTP01982  NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) 21.0
 LDTP10032  7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) 20.8
 LDTP07679  Lysocardiolipin acyltransferase 1 (LCLAT1) 20.8
 LDTP01329  Lathosterol oxidase (SC5D) 20.7
 LDTP06270  Signal peptidase complex subunit 2 (SPCS2) 20.7
 LDTP11199  DCN1-like protein 5 (DCUN1D5) 20.3
 LDTP04689  Adenosine kinase (ADK) 20.1
 LDTP11259  Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) 20.1
 LDTP09874  Endoplasmic reticulum protein SC65 (P3H4) 20.1
 LDTP01687  Apoptosis-inducing factor 1, mitochondrial (AIFM1) 19.7
 LDTP04008  Endothelin-converting enzyme 1 (ECE1) 19.7
 LDTP02385  Leukotriene A-4 hydrolase (LTA4H) 19.7
 LDTP00597  Serine palmitoyltransferase 1 (SPTLC1) 19.7
 LDTP07990  Heparan sulfate 2-O-sulfotransferase 1 (HS2ST1) 19.6
 LDTP13358  Leucyl-cystinyl aminopeptidase (LNPEP) 19.6
 LDTP09396  Minor histocompatibility antigen H13 (HM13) 19.6
 LDTP03779  Copper-transporting ATPase 2 (ATP7B) 19.2
 LDTP07762  Hydroxysteroid dehydrogenase-like protein 2 (HSDL2) 18.9
 LDTP01535  Kinesin-like protein KIF20A (KIF20A) 18.8
 LDTP11055  Telomerase RNA component interacting RNase (TRIR) 18.5
 LDTP12954  Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 (HACD3) 18.3
 LDTP08728  Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1L1) 18.3
 LDTP06617  Ceramide glucosyltransferase (UGCG) 18.0
 LDTP06375  Delta(24)-sterol reductase (DHCR24) 18.0
 LDTP03198  Ferrochelatase, mitochondrial (FECH) 18.0
 LDTP02367  Cytochrome c oxidase subunit 6C (COX6C) 17.9
 LDTP05480  Amidophosphoribosyltransferase (PPAT) 17.8
 LDTP14079  E3 ubiquitin-protein ligase ARIH1 (ARIH1) 17.8
 LDTP15480  Prenylcysteine oxidase-like (PCYOX1L) 17.8
 LDTP05549  Protein phosphatase 3 catalytic subunit alpha (PPP3CA) 17.6
 LDTP08209  Acyl-coenzyme A thioesterase 1 (ACOT1) 17.5
 LDTP04120  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (STT3A) 17.4
 LDTP09088  Phospholipase A2 group XV (PLA2G15) 17.3
 LDTP10471  Protein disulfide-isomerase TMX3 (TMX3) 17.1
 LDTP05588  RNA cytosine C(5)-methyltransferase NSUN2 (NSUN2) 17.1
 LDTP06333  Serum paraoxonase/arylesterase 2 (PON2) 17.1
 LDTP12543  14 kDa phosphohistidine phosphatase (PHPT1) 16.8
 LDTP11225  Deoxyhypusine hydroxylase (DOHH) 16.7
 LDTP04261  Choline-phosphate cytidylyltransferase A (PCYT1A) 16.6
 LDTP09835  GPI-anchor transamidase (PIGK) 16.6
 LDTP13303  NADH-cytochrome b5 reductase 1 (CYB5R1) 16.4
 LDTP00316  Ribonuclease T2 (RNASET2) 16.3
 LDTP13131  7-dehydrocholesterol reductase (DHCR7) 16.1
 LDTP03787  Choline kinase alpha (CHKA) 16.1
 LDTP06620  Thiosulfate sulfurtransferase (TST) 16.1
 LDTP15484  Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) 16.0
 LDTP02067  Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) 16.0
 LDTP19478  Putative peptidyl-tRNA hydrolase PTRHD1 (PTRHD1) 15.9
 LDTP00907  Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (PDE6D) 15.8
 LDTP14075  AFG3-like protein 2 (AFG3L2) 15.7
 LDTP08385  NADH dehydrogenase 1 alpha subcomplex subunit 11 (NDUFA11) 15.7
 LDTP02169  Beta-hexosaminidase subunit alpha (HEXA) 15.6
 LDTP09095  Diacylglycerol lipase-beta (DAGLB) 15.6
 LDTP06977  GPI ethanolamine phosphate transferase 2 (PIGG) 15.6
 LDTP08666  Xaa-Arg dipeptidase (PM20D2) 15.5
 LDTP04345  Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A) 15.3
 LDTP10177  Medium-chain acyl-CoA ligase ACSF2, mitochondrial (ACSF2) 15.3
 LDTP06501  Ras-related protein Rab-11B (RAB11B) 15.3
 LDTP05446  Ubiquitin-protein ligase E3A (UBE3A) 15.3
 LDTP03001  E3 ubiquitin-protein ligase TRIM21 (TRIM21) 15.2
 LDTP00890  S-adenosylhomocysteine hydrolase-like protein 1 (AHCYL1) 15.2
 LDTP13107  SUMO-activating enzyme subunit 1 (SAE1) 15.2
 LDTP11268  Acireductone dioxygenase (ADI1) 15.1
 LDTP09388  Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (STT3B) 15.0
Transporter and channel
Click to Show/Hide to Show 80 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP10913  Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) 99.7
 LDTP01059  Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) 99.7
 LDTP11615  Protein tweety homolog 3 (TTYH3) 99.7
 LDTP07667  Transmembrane protein 205 (TMEM205) 99.7
 LDTP02724  Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) 77.7
 LDTP04237  Protein ERGIC-53 (LMAN1) 74.0
 LDTP00547  Secretory carrier-associated membrane protein 2 (SCAMP2) 65.3
 LDTP02645  Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) 63.1
 LDTP03905  Peroxisomal biogenesis factor 19 (PEX19) 61.8
 LDTP18448  Transmembrane 9 superfamily member 3 (TM9SF3) 61.8
 LDTP04071  Voltage-dependent anion-selective channel protein 2 (VDAC2) 61.0
 LDTP02215  Prosaposin (PSAP) 59.3
 LDTP03132  Voltage-dependent anion-selective channel protein 1 (VDAC1) 58.9
 LDTP04033  Translocon-associated protein subunit alpha (SSR1) 56.5
 LDTP14952  Mpv17-like protein 2 (MPV17L2) 54.9
 LDTP16813  Tetraspanin-3 (TSPAN3) 54.6
 LDTP11813  Solute carrier family 25 member 32 (SLC25A32) 53.8
 LDTP01745  Putative lipid scramblase CLPTM1 (CLPTM1) 49.5
 LDTP06928  Coiled-coil domain-containing protein 93 (CCDC93) 48.5
 LDTP15987  Sorting nexin-25 (SNX25) 48.2
 LDTP01671  STARD3 N-terminal-like protein (STARD3NL) 45.9
 LDTP06034  Lysosome membrane protein 2 (SCARB2) 45.3
 LDTP14511  ATP synthase subunit g, mitochondrial (ATP5MG) 41.4
 LDTP03277  ER lumen protein-retaining receptor 1 (KDELR1) 40.5
 LDTP09968  V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) 38.9
 LDTP05511  Cytoskeleton-associated protein 4 (CKAP4) 38.1
 LDTP07885  Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) 37.0
 LDTP05900  Metaxin-1 (MTX1) 36.8
 LDTP06308  Mitochondrial inner membrane protein OXA1L (OXA1L) 34.8
 LDTP13174  Mitochondrial dicarboxylate carrier (SLC25A10) 33.1
 LDTP15948  Transmembrane protein 126A (TMEM126A) 33.1
 LDTP03284  ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) 32.4
 LDTP14140  Ceramide transfer protein (CERT1) 30.9
 LDTP03380  Stomatin (STOM) 30.9
 LDTP00562  Membrane-associated progesterone receptor component 2 (PGRMC2) 30.7
 LDTP10958  Sigma non-opioid intracellular receptor 1 (SIGMAR1) 30.1
 LDTP03064  Cytochrome c oxidase subunit 5A, mitochondrial (COX5A) 26.9
 LDTP14178  Heme transporter FLVCR1 (FLVCR1) 26.9
 LDTP01217  Metaxin-2 (MTX2) 26.7
 LDTP13969  Transmembrane emp24 domain-containing protein 7 (TMED7) 26.4
 LDTP17362  Magnesium transporter NIPA3 (NIPAL1) 25.1
 LDTP16069  Peroxisomal membrane protein 2 (PXMP2) 24.9
 LDTP05814  Battenin (CLN3) 24.6
 LDTP00857  Syntaxin-6 (STX6) 23.8
 LDTP00235  Membrane-associated progesterone receptor component 1 (PGRMC1) 23.6
 LDTP04462  H(+)/Cl(-) exchange transporter 6 (CLCN6) 23.4
 LDTP10499  Lipid scramblase CLPTM1L (CLPTM1L) 23.3
 LDTP11213  Nucleoporin NDC1 (NDC1) 22.8
 LDTP06855  Anoctamin-6 (ANO6) 22.5
 LDTP12909  Mitochondrial carrier homolog 1 (MTCH1) 22.0
 LDTP06945  Sigma intracellular receptor 2 (TMEM97) 22.0
 LDTP09547  Scavenger receptor class B member 1 (SCARB1) 20.8
 LDTP11116  45 kDa calcium-binding protein (SDF4) 20.4
 LDTP00865  Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) 20.1
 LDTP20002  Transmembrane protein 160 (TMEM160) 19.8
 LDTP15967  Tetraspanin-10 (TSPAN10) 19.7
 LDTP09333  Golgin subfamily A member 5 (GOLGA5) 19.3
 LDTP13983  Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) 19.3
 LDTP00541  NPC intracellular cholesterol transporter 1 (NPC1) 19.2
 LDTP10065  Transmembrane protein 230 (TMEM230) 18.8
 LDTP01525  Mitochondrial proton/calcium exchanger protein (LETM1) 18.3
 LDTP01454  SUN domain-containing protein 1 (SUN1) 17.9
 LDTP11229  Transmembrane protein 70, mitochondrial (TMEM70) 17.5
 LDTP06660  MICOS complex subunit MIC60 (IMMT) 17.1
 LDTP01574  Importin-7 (IPO7) 17.0
 LDTP07156  Protein wntless homolog (WLS) 17.0
 LDTP04459  H(+)/Cl(-) exchange transporter 3 (CLCN3) 16.9
 LDTP09328  Adenosine 3'-phospho 5'-phosphosulfate transporter 1 (SLC35B2) 16.8
 LDTP02061  Anion exchange protein 2 (SLC4A2) 16.8
 LDTP01542  Golgi SNAP receptor complex member 1 (GOSR1) 16.6
 LDTP13824  Voltage-dependent anion-selective channel protein 3 (VDAC3) 16.4
 LDTP10669  Melanoma inhibitory activity protein 2 (MIA2) 16.2
 LDTP10059  PAT complex subunit CCDC47 (CCDC47) 16.1
 LDTP08651  Exocyst complex component 8 (EXOC8) 16.0
 LDTP11732  Magnesium transporter protein 1 (MAGT1) 15.8
 LDTP11162  Solute carrier family 25 member 33 (SLC25A33) 15.8
 LDTP13393  Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (SLC25A13) 15.6
 LDTP09515  Importin-4 (IPO4) 15.6
 LDTP16190  Protein FAM8A1 (FAM8A1) 15.6
 LDTP04924  V-type proton ATPase subunit d 1 (ATP6V0D1) 15.0
Transcription factor
Click to Show/Hide to Show 8 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP08006  PHD finger-like domain-containing protein 5A (PHF5A) 52.0
 LDTP06341  Non-POU domain-containing octamer-binding protein (NONO) 30.3
 LDTP08409  Transcriptional repressor p66-alpha (GATAD2A) 21.9
 LDTP02343  High mobility group protein B1 (HMGB1) 21.7
 LDTP03043  Transcription factor BTF3 (BTF3) 16.2
 LDTP00612  High mobility group protein B3 (HMGB3) 15.8
 LDTP10501  DnaJ homolog subfamily C member 1 (DNAJC1) 15.2
 LDTP00576  NF-kappa-B-repressing factor (NKRF) 15.0
GPCR
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15303  Membrane progestin receptor alpha (PAQR7) 64.0
Immunoglobulin
Click to Show/Hide to Show 1 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP02688  HLA class I histocompatibility antigen, alpha chain E (HLA-E) 58.1
Other
Click to Show/Hide to Show 146 Protein Related to This Bioclass
Target ID Target Name Binding Ratio
 LDTP15420  Mitochondrial import receptor subunit TOM5 homolog (TOMM5) 99.7
 LDTP01522  Reticulon-3 (RTN3) 99.7
 LDTP05277  Protein SET (SET) 95.7
 LDTP00281  Golgi integral membrane protein 4 (GOLIM4) 89.9
 LDTP12565  Mitochondrial import receptor subunit TOM22 homolog (TOMM22) 85.0
 LDTP11076  Apolipoprotein L2 (APOL2) 80.4
 LDTP07891  Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) 72.0
 LDTP12468  Diablo IAP-binding mitochondrial protein (DIABLO) 71.5
 LDTP13086  Syntaxin-18 (STX18) 70.5
 LDTP15067  Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) 56.9
 LDTP14458  Tetraspanin-6 (TSPAN6) 55.3
 LDTP00105  Protein unc-119 homolog B (UNC119B) 54.6
 LDTP12025  UPF0488 protein C8orf33 (C8orf33) 53.8
 LDTP18883  Protein CEBPZOS (CEBPZOS) 50.9
 LDTP05160  Nucleobindin-2 (NUCB2) 47.8
 LDTP00759  Tumor protein D54 (TPD52L2) 44.0
 LDTP10056  Protein FAM162A (FAM162A) 42.5
 LDTP05049  Dynein light chain 1, cytoplasmic (DYNLL1) 41.1
 LDTP11021  Endophilin-A3 (SH3GL3) 40.2
 LDTP08364  Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) 39.4
 LDTP12077  Jupiter microtubule associated homolog 2 (JPT2) 38.9
 LDTP13828  Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) 38.3
 LDTP00850  ER lumen protein-retaining receptor 3 (KDELR3) 36.8
 LDTP00986  Syntaxin-10 (STX10) 34.8
 LDTP00417  Programmed cell death protein 5 (PDCD5) 34.3
 LDTP11101  Coronin-1B (CORO1B) 34.1
 LDTP13981  Small ribosomal subunit protein bS16m (MRPS16) 34.1
 LDTP12780  THUMP domain-containing protein 1 (THUMPD1) 34.1
 LDTP02736  Myosin light chain 6B (MYL6B) 33.4
 LDTP12476  Translation initiation factor eIF2B subunit gamma (EIF2B3) 33.4
 LDTP08292  Zinc finger CCCH domain-containing protein 18 (ZC3H18) 33.1
 LDTP02940  Large ribosomal subunit protein eL33 (RPL35A) 31.8
 LDTP02816  Replication protein A 32 kDa subunit (RPA2) 31.3
 LDTP08154  Large ribosomal subunit protein uL10m (MRPL10) 31.1
 LDTP04094  Large proline-rich protein BAG6 (BAG6) 30.5
 LDTP04926  Large ribosomal subunit protein eL43 (RPL37A) 30.3
 LDTP14259  Testis-expressed protein 264 (TEX264) 30.3
 LDTP14486  Clustered mitochondria protein homolog (CLUH) 27.3
 LDTP08689  Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) 27.3
 LDTP07031  Collectin-12 (COLEC12) 27.1
 LDTP09920  Golgi apparatus protein 1 (GLG1) 27.1
 LDTP05942  Periodic tryptophan protein 1 homolog (PWP1) 26.9
 LDTP04356  Emerin (EMD) 26.2
 LDTP10684  RNA-binding protein 14 (RBM14) 26.0
 LDTP09112  Nonsense-mediated mRNA decay factor SMG8 (SMG8) 25.6
 LDTP11533  Oxysterol-binding protein-related protein 6 (OSBPL6) 25.6
 LDTP08594  Negative elongation factor C/D (NELFCD) 25.5
 LDTP06587  Survival motor neuron protein (SMN1; SMN2) 25.5
 LDTP07368  Tetratricopeptide repeat protein 19, mitochondrial (TTC19) 25.5
 LDTP05068  Tropomyosin alpha-4 chain (TPM4) 25.5
 LDTP16192  Mitochondrial fission process protein 1 (MTFP1) 24.9
 LDTP10093  Mitochondrial calcium uniporter regulator 1 (MCUR1) 24.8
 LDTP13817  Nuclear migration protein nudC (NUDC) 24.3
 LDTP05868  Protein unc-119 homolog A (UNC119) 23.6
 LDTP05715  Vesicle transport protein SEC20 (BNIP1) 23.6
 LDTP08552  PHD finger protein 6 (PHF6) 22.9
 LDTP18373  Thioredoxin-related transmembrane protein 4 (TMX4) 22.3
 LDTP02297  Vimentin (VIM) 22.0
 LDTP13956  Putative RNA-binding protein Luc7-like 2 (LUC7L2) 21.7
 LDTP02335  U1 small nuclear ribonucleoprotein C (SNRPC) 21.6
 LDTP05768  Heterogeneous nuclear ribonucleoprotein A0 (HNRNPA0) 21.4
 LDTP04049  Ran-specific GTPase-activating protein (RANBP1) 21.3
 LDTP06097  Reticulocalbin-2 (RCN2) 21.0
 LDTP09938  Far upstream element-binding protein 2 (KHSRP) 20.8
 LDTP00887  Calumenin (CALU) 20.7
 LDTP01206  Vesicle-trafficking protein SEC22b (SEC22B) 20.7
 LDTP03027  Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) 20.4
 LDTP02181  Neurofilament medium polypeptide (NEFM) 20.4
 LDTP16006  Optic atrophy 3 protein (OPA3) 20.4
 LDTP02164  Nucleophosmin (NPM1) 20.3
 LDTP08224  Protein LYRIC (MTDH) 20.3
 LDTP00199  HCLS1-associated protein X-1 (HAX1) 20.1
 LDTP04108  Large ribosomal subunit protein eL28 (RPL28) 20.1
 LDTP11906  Phosphatidylinositol glycan anchor biosynthesis class U protein (PIGU) 20.1
 LDTP16162  Large ribosomal subunit protein bL27m (MRPL27) 20.0
 LDTP08136  YTH domain-containing family protein 3 (YTHDF3) 20.0
 LDTP05189  Chromobox protein homolog 1 (CBX1) 19.8
 LDTP06952  DBIRD complex subunit ZNF326 (ZNF326) 19.8
 LDTP09324  Ganglioside-induced differentiation-associated protein 1 (GDAP1) 19.8
 LDTP04382  Kinetochore-associated protein 1 (KNTC1) 19.7
 LDTP16080  Protein FAM114A2 (FAM114A2) 19.7
 LDTP00849  17S U2 SnRNP complex component HTATSF1 (HTATSF1) 19.6
 LDTP07318  HAUS augmin-like complex subunit 3 (HAUS3) 19.6
 LDTP12652  DDB1- and CUL4-associated factor 13 (DCAF13) 19.4
 LDTP19021  EF-hand calcium-binding domain-containing protein 14 (EFCAB14) 19.3
 LDTP03614  Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) 19.3
 LDTP05375  Nucleobindin-1 (NUCB1) 19.3
 LDTP03775  RNA-binding protein FUS (FUS) 19.3
 LDTP16323  Signal recognition particle receptor subunit beta (SRPRB) 19.3
 LDTP04627  UV excision repair protein RAD23 homolog B (RAD23B) 19.3
 LDTP11764  Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (NUCKS1) 19.0
 LDTP12506  DNA polymerase epsilon subunit 3 (POLE3) 18.9
 LDTP13919  Thyroid hormone receptor-associated protein 3 (THRAP3) 18.9
 LDTP12764  MICOS complex subunit MIC19 (CHCHD3) 18.6
 LDTP09850  Proline-rich protein PRCC (PRCC) 18.6
 LDTP08950  ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) 18.5
 LDTP08984  Protein enabled homolog (ENAH) 18.5
 LDTP01320  Eukaryotic translation initiation factor 3 subunit J (EIF3J) 18.4
 LDTP05224  RNA-binding protein 10 (RBM10) 18.4
 LDTP00830  BUB3-interacting and GLEBS motif-containing protein ZNF207 (ZNF207) 18.3
 LDTP11312  DET1- and DDB1-associated protein 1 (DDA1) 18.3
 LDTP10965  Nucleosome assembly protein 1-like 4 (NAP1L4) 18.3
 LDTP00024  Rho GTPase-activating protein 10 (ARHGAP10) 18.3
 LDTP04945  Small ubiquitin-related modifier 2 (SUMO2) 18.3
 LDTP04914  Large ribosomal subunit protein uL24 (RPL26) 18.1
 LDTP06094  Src substrate cortactin (CTTN) 18.0
 LDTP06879  Protein FAM98B (FAM98B) 17.9
 LDTP04140  Large ribosomal subunit protein eL29 (RPL29) 17.8
 LDTP06301  Eukaryotic translation initiation factor 4H (EIF4H) 17.6
 LDTP05226  RNA-binding protein 3 (RBM3) 17.5
 LDTP06373  Mitochondrial import receptor subunit TOM20 homolog (TOMM20) 17.4
 LDTP08735  Spartin (SPART) 17.4
 LDTP07476  RAD50-interacting protein 1 (RINT1) 17.3
 LDTP13311  Poly(U)-binding-splicing factor PUF60 (PUF60) 17.1
 LDTP03554  Sorcin (SRI) 17.1
 LDTP02165  Tropomyosin alpha-3 chain (TPM3) 17.1
 LDTP00620  Eukaryotic translation initiation factor 3 subunit H (EIF3H) 17.0
 LDTP03968  Lamina-associated polypeptide 2, isoforms beta/gamma (TMPO) 17.0
 LDTP05442  14-3-3 protein eta (YWHAH) 16.9
 LDTP02124  Keratin, type I cytoskeletal 18 (KRT18) 16.8
 LDTP01932  Prelamin-A/C (LMNA) 16.8
 LDTP05960  Trophoblast glycoprotein (TPBG) 16.8
 LDTP05533  Kinesin light chain 1 (KLC1) 16.7
 LDTP08073  Tetratricopeptide repeat protein 21B (TTC21B) 16.7
 LDTP19963  TraB domain-containing protein (TRABD) 16.6
 LDTP07947  Eukaryotic translation initiation factor 3 subunit M (EIF3M) 16.4
 LDTP02869  Stathmin (STMN1) 16.4
 LDTP06383  Calponin-3 (CNN3) 16.2
 LDTP05867  Treacle protein (TCOF1) 16.2
 LDTP01466  HAUS augmin-like complex subunit 5 (HAUS5) 16.1
 LDTP13978  Ubiquitin-fold modifier-conjugating enzyme 1 (UFC1) 16.1
 LDTP13467  RNA-binding protein Raly (RALY) 16.0
 LDTP00632  Syntaxin-7 (STX7) 16.0
 LDTP15762  Zinc finger RNA-binding protein (ZFR) 15.7
 LDTP03545  Alpha-2-macroglobulin receptor-associated protein (LRPAP1) 15.6
 LDTP12826  Bcl-2-associated transcription factor 1 (BCLAF1) 15.6
 LDTP12412  Reticulon-4 (RTN4) 15.6
 LDTP16096  RNA-binding protein 12 (RBM12) 15.6
 LDTP05834  Eukaryotic translation initiation factor 3 subunit I (EIF3I) 15.5
 LDTP06583  Serine/arginine-rich splicing factor 7 (SRSF7) 15.5
 LDTP00500  Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) 15.1
 LDTP01361  DnaJ homolog subfamily C member 8 (DNAJC8) 15.0
 LDTP08795  GH3 domain-containing protein (GHDC) 15.0
 LDTP03065  Lamin-B1 (LMNB1) 15.0
 LDTP06220  LIM and SH3 domain protein 1 (LASP1) 15.0
 LDTP13870  Nischarin (NISCH) 15.0

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587