Details of the Target

General Information of Target

Target ID LDTP06879
Target Name Protein FAM98B (FAM98B)
Gene Name FAM98B
Gene ID 283742
Synonyms
Protein FAM98B
3D Structure
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2D Sequence (FASTA)
Download
3D Structure (PDB)
Download
Sequence
MRGPEPGPQPTMEGDVLDTLEALGYKGPLLEEQALTKAAEGGLSSPEFSELCIWLGSQIK
SLCNLEESITSAGRDDLESFQLEISGFLKEMACPYSVLISGDIKDRLKKKEDCLKLLLFL
STELQASQILQNKKHKNSQLDKNSEVYQEVQAMFDTLGIPKSTTSDIPHMLNQVESKVKD
ILSKVQKNHVGKPLLKMDLNSEQAEQLERINDALSCEYECRRRMLMKRLDVTVQSFGWSD
RAKVKTDDIARIYQPKRYALSPKTTITMAHLLAAREDLSKIIRTSSGTSREKTACAINKV
LMGRVPDRGGRPNEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWG
GGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGG
GGGGGGGGGYRRY
Target Bioclass
Other
Family
FAM98 family
Subcellular location
Nucleus
Function Positively stimulates PRMT1-induced protein arginine dimethylated arginine methylation.
Uniprot ID
Q52LJ0
Ensemble ID
ENST00000397609.6
HGNC ID
HGNC:26773

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 29 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		13.73  LDD0402  [1]
TH211
 Probe Info  		Y147(14.81)  LDD0260  [2]
STPyne
 Probe Info  		K184(10.00); K256(10.00)  LDD0277  [3]
BTD
 Probe Info  		C295(4.53)  LDD1699  [4]
Probe 1
 Probe Info  		Y258(26.48); Y410(27.67); Y414(57.59)  LDD3495  [5]
DBIA
 Probe Info  		C52(4.06); C93(2.22)  LDD3312  [6]
AHL-Pu-1
 Probe Info  		C216(3.41)  LDD0169  [7]
HHS-475
 Probe Info  		Y147(0.79); Y258(0.86)  LDD0264  [8]
ATP probe
 Probe Info  		K299(0.00); K292(0.00)  LDD0199  [9]
4-Iodoacetamidophenylacetylene
 Probe Info  		C52(0.00); C295(0.00); C93(0.00); C220(0.00)  LDD0038  [10]
IA-alkyne
 Probe Info  		C216(0.00); C295(0.00); C93(0.00)  LDD0032  [11]
Lodoacetamide azide
 Probe Info  		C52(0.00); C93(0.00); C220(0.00); C216(0.00)  LDD0037  [10]
JW-RF-010
 Probe Info  		C93(0.00); C216(0.00)  LDD0026  [12]
TFBX
 Probe Info  		C216(0.00); C220(0.00)  LDD0027  [12]
WYneN
 Probe Info  		C216(0.00); C295(0.00)  LDD0021  [13]
WYneO
 Probe Info  		C216(0.00); C63(0.00)  LDD0022  [13]
Compound 10
 Probe Info  		C216(0.00); C295(0.00); C63(0.00)  LDD2216  [14]
Compound 11
 Probe Info  		C216(0.00); C63(0.00)  LDD2213  [14]
ENE
 Probe Info  		N.A.  LDD0006  [13]
IPM
 Probe Info  		N.A.  LDD0005  [13]
VSF
 Probe Info  		N.A.  LDD0007  [13]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [15]
1c-yne
 Probe Info  		K263(0.00); K142(0.00)  LDD0228  [16]
Acrolein
 Probe Info  		C216(0.00); C63(0.00); C220(0.00)  LDD0217  [17]
Crotonaldehyde
 Probe Info  		N.A.  LDD0219  [17]
Methacrolein
 Probe Info  		C216(0.00); C220(0.00); C63(0.00)  LDD0218  [17]
W1
 Probe Info  		C63(0.00); C216(0.00); C295(0.00); C93(0.00)  LDD0236  [18]
AOyne
 Probe Info  		15.00  LDD0443  [19]
NAIA_5
 Probe Info  		C52(0.00); C295(0.00); C93(0.00); C220(0.00)  LDD2223  [20]
PAL-AfBPP Probe
Click To Hide/Show 13 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C187
 Probe Info  		17.88  LDD1865  [21]
C191
 Probe Info  		16.34  LDD1868  [21]
C193
 Probe Info  		7.11  LDD1869  [21]
C207
 Probe Info  		17.88  LDD1882  [21]
C243
 Probe Info  		16.11  LDD1916  [21]
C397
 Probe Info  		9.58  LDD2056  [21]
FFF probe11
 Probe Info  		12.43  LDD0472  [22]
FFF probe13
 Probe Info  		10.86  LDD0475  [22]
FFF probe14
 Probe Info  		12.07  LDD0477  [22]
FFF probe3
 Probe Info  		8.25  LDD0465  [22]
STS-2
 Probe Info  		N.A.  LDD0139  [23]
VE-P
 Probe Info  		N.A.  LDD0396  [24]
Diazir
 Probe Info  		C216(0.00); E217(0.00)  LDD0011  [13]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0548  1-(4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-2-nitroethan-1-one MDA-MB-231 C113(0.80); C63(0.55)  LDD2142  [4]
 LDCM0519  1-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-2-nitroethan-1-one MDA-MB-231 C113(0.78); C295(1.17)  LDD2112  [4]
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C113(1.20); C63(1.74)  LDD2117  [4]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C113(1.58); C295(1.09)  LDD2152  [4]
 LDCM0025  4SU-RNA DM93 C93(17.83)  LDD0170  [7]
 LDCM0026  4SU-RNA+native RNA HEK-293T C216(3.41)  LDD0169  [7]
 LDCM0214  AC1 HEK-293T C63(0.94); C93(1.04); C52(1.03); C216(0.96)  LDD1507  [25]
 LDCM0215  AC10 HEK-293T C63(0.96); C93(1.14); C52(1.03); C216(0.86)  LDD1508  [25]
 LDCM0226  AC11 HEK-293T C63(0.92); C93(1.01); C52(0.97); C216(1.03)  LDD1509  [25]
 LDCM0237  AC12 HEK-293T C63(0.90); C93(1.04); C52(1.12); C216(0.94)  LDD1510  [25]
 LDCM0259  AC14 HEK-293T C63(0.91); C93(1.04); C52(1.05); C216(1.00)  LDD1512  [25]
 LDCM0270  AC15 HEK-293T C63(0.97); C93(1.06); C52(1.10); C216(0.99)  LDD1513  [25]
 LDCM0276  AC17 HEK-293T C63(0.99); C93(0.97); C52(0.96); C216(0.97)  LDD1515  [25]
 LDCM0277  AC18 HEK-293T C63(0.99); C93(1.07); C52(0.90); C216(0.91)  LDD1516  [25]
 LDCM0278  AC19 HEK-293T C63(0.83); C93(0.88); C52(0.80); C216(0.73)  LDD1517  [25]
 LDCM0279  AC2 HEK-293T C63(0.96); C93(1.14); C52(1.06); C216(0.87)  LDD1518  [25]
 LDCM0280  AC20 HEK-293T C63(0.90); C93(1.10); C52(0.99); C216(0.96)  LDD1519  [25]
 LDCM0281  AC21 HEK-293T C63(0.98); C93(1.05); C52(1.04); C216(0.90)  LDD1520  [25]
 LDCM0282  AC22 HEK-293T C63(1.03); C93(1.12); C52(1.06); C216(0.99)  LDD1521  [25]
 LDCM0283  AC23 HEK-293T C63(0.97); C93(1.09); C52(1.03); C216(0.97)  LDD1522  [25]
 LDCM0284  AC24 HEK-293T C63(1.03); C93(1.02); C52(0.85); C216(0.99)  LDD1523  [25]
 LDCM0285  AC25 HEK-293T C63(0.94); C93(0.99); C52(1.06); C216(0.88)  LDD1524  [25]
 LDCM0286  AC26 HEK-293T C63(0.94); C93(1.07); C52(1.03); C216(0.95)  LDD1525  [25]
 LDCM0287  AC27 HEK-293T C63(0.90); C93(1.01); C52(1.02); C216(0.94)  LDD1526  [25]
 LDCM0288  AC28 HEK-293T C63(0.96); C93(1.03); C52(1.06); C216(1.02)  LDD1527  [25]
 LDCM0289  AC29 HEK-293T C63(0.98); C93(1.02); C52(0.95); C216(0.94)  LDD1528  [25]
 LDCM0290  AC3 HEK-293T C63(0.90); C93(1.03); C52(1.02); C216(0.95)  LDD1529  [25]
 LDCM0291  AC30 HEK-293T C63(0.91); C93(1.12); C52(1.03); C216(1.02)  LDD1530  [25]
 LDCM0292  AC31 HEK-293T C63(0.94); C93(1.11); C52(1.03); C216(0.98)  LDD1531  [25]
 LDCM0293  AC32 HEK-293T C63(0.95); C93(0.97); C52(0.81); C216(0.97)  LDD1532  [25]
 LDCM0294  AC33 HEK-293T C63(0.91); C93(1.04); C52(1.13); C216(0.90)  LDD1533  [25]
 LDCM0295  AC34 HEK-293T C63(0.95); C93(1.06); C52(1.05); C216(0.88)  LDD1534  [25]
 LDCM0296  AC35 HEK-293T C63(0.89); C93(0.98); C52(1.00); C216(0.94)  LDD1535  [25]
 LDCM0297  AC36 HEK-293T C63(0.93); C93(1.08); C52(1.03); C216(0.89)  LDD1536  [25]
 LDCM0298  AC37 HEK-293T C63(0.98); C93(1.08); C52(0.91); C216(0.87)  LDD1537  [25]
 LDCM0299  AC38 HEK-293T C63(0.87); C93(1.15); C52(1.06); C216(0.95)  LDD1538  [25]
 LDCM0300  AC39 HEK-293T C63(0.95); C93(1.08); C52(1.08); C216(0.95)  LDD1539  [25]
 LDCM0301  AC4 HEK-293T C63(0.96); C93(1.11); C52(1.01); C216(0.95)  LDD1540  [25]
 LDCM0302  AC40 HEK-293T C63(1.03); C93(0.98); C52(0.92); C216(0.94)  LDD1541  [25]
 LDCM0303  AC41 HEK-293T C63(0.92); C93(0.97); C52(1.07); C216(1.01)  LDD1542  [25]
 LDCM0304  AC42 HEK-293T C63(0.96); C93(1.06); C52(1.01); C216(0.90)  LDD1543  [25]
 LDCM0305  AC43 HEK-293T C63(0.86); C93(1.03); C52(1.03); C216(0.90)  LDD1544  [25]
 LDCM0306  AC44 HEK-293T C63(0.90); C93(1.09); C52(1.11); C216(0.86)  LDD1545  [25]
 LDCM0307  AC45 HEK-293T C63(0.96); C93(0.99); C52(1.06); C216(0.92)  LDD1546  [25]
 LDCM0308  AC46 HEK-293T C63(0.88); C93(1.09); C52(0.99); C216(0.96)  LDD1547  [25]
 LDCM0309  AC47 HEK-293T C63(0.93); C93(1.10); C52(0.97); C216(0.98)  LDD1548  [25]
 LDCM0310  AC48 HEK-293T C63(0.96); C93(1.05); C52(0.89); C216(0.99)  LDD1549  [25]
 LDCM0311  AC49 HEK-293T C63(0.93); C93(0.99); C52(1.04); C216(1.00)  LDD1550  [25]
 LDCM0312  AC5 HEK-293T C63(0.97); C93(1.05); C52(1.03); C216(0.94)  LDD1551  [25]
 LDCM0313  AC50 HEK-293T C63(0.97); C93(1.10); C52(1.10); C216(0.87)  LDD1552  [25]
 LDCM0314  AC51 HEK-293T C63(0.99); C93(1.09); C52(1.11); C216(0.88)  LDD1553  [25]
 LDCM0315  AC52 HEK-293T C63(0.94); C93(1.00); C52(1.00); C216(0.96)  LDD1554  [25]
 LDCM0316  AC53 HEK-293T C63(0.95); C93(1.05); C52(1.05); C216(0.93)  LDD1555  [25]
 LDCM0317  AC54 HEK-293T C63(0.92); C93(1.02); C52(1.07); C216(0.88)  LDD1556  [25]
 LDCM0318  AC55 HEK-293T C63(0.98); C93(1.06); C52(1.04); C216(0.97)  LDD1557  [25]
 LDCM0319  AC56 HEK-293T C63(1.00); C93(1.02); C52(0.96); C216(0.93)  LDD1558  [25]
 LDCM0320  AC57 HEK-293T C63(0.97); C93(0.98); C52(1.06); C216(0.95)  LDD1559  [25]
 LDCM0321  AC58 HEK-293T C63(0.93); C93(1.13); C52(1.02); C216(0.91)  LDD1560  [25]
 LDCM0322  AC59 HEK-293T C63(0.92); C93(1.10); C52(1.10); C216(0.93)  LDD1561  [25]
 LDCM0323  AC6 HEK-293T C63(0.90); C93(1.06); C52(1.10); C216(1.01)  LDD1562  [25]
 LDCM0324  AC60 HEK-293T C63(0.91); C93(1.06); C52(0.99); C216(0.98)  LDD1563  [25]
 LDCM0325  AC61 HEK-293T C63(0.96); C93(1.09); C52(1.06); C216(0.99)  LDD1564  [25]
 LDCM0326  AC62 HEK-293T C63(0.90); C93(1.18); C52(1.00); C216(0.94)  LDD1565  [25]
 LDCM0327  AC63 HEK-293T C63(0.97); C93(1.13); C52(1.12); C216(0.97)  LDD1566  [25]
 LDCM0328  AC64 HEK-293T C63(0.96); C93(1.15); C52(0.84); C216(0.97)  LDD1567  [25]
 LDCM0334  AC7 HEK-293T C63(1.00); C93(1.16); C52(1.07); C216(0.95)  LDD1568  [25]
 LDCM0345  AC8 HEK-293T C63(0.95); C93(1.09); C52(0.81); C216(0.96)  LDD1569  [25]
 LDCM0520  AKOS000195272 MDA-MB-231 C113(0.61); C63(0.79)  LDD2113  [4]
 LDCM0248  AKOS034007472 HEK-293T C63(0.97); C93(1.02); C52(1.00); C216(0.92)  LDD1511  [25]
 LDCM0356  AKOS034007680 HEK-293T C63(0.94); C93(0.96); C52(1.04); C216(1.05)  LDD1570  [25]
 LDCM0275  AKOS034007705 HEK-293T C63(0.96); C93(1.00); C52(0.85); C216(0.97)  LDD1514  [25]
 LDCM0156  Aniline NCI-H1299 12.20  LDD0403  [1]
 LDCM0498  BS-3668 MDA-MB-231 C295(0.55); C63(1.06)  LDD2091  [4]
 LDCM0630  CCW28-3 231MFP C216(1.73); C63(1.60)  LDD2214  [26]
 LDCM0108  Chloroacetamide HeLa C63(0.00); H270(0.00); C216(0.00); C220(0.00)  LDD0222  [17]
 LDCM0632  CL-Sc Hep-G2 C295(0.98)  LDD2227  [20]
 LDCM0367  CL1 HEK-293T C63(1.19); C93(1.12); C52(1.18); C216(0.85)  LDD1571  [25]
 LDCM0368  CL10 HEK-293T C63(0.84); C93(0.93); C52(0.91); C216(0.84)  LDD1572  [25]
 LDCM0369  CL100 HEK-293T C63(0.94); C93(1.15); C52(0.95); C216(0.90)  LDD1573  [25]
 LDCM0370  CL101 HEK-293T C63(0.91); C93(1.08); C52(1.05); C216(0.98)  LDD1574  [25]
 LDCM0371  CL102 HEK-293T C63(0.96); C93(1.05); C52(1.01); C216(0.90)  LDD1575  [25]
 LDCM0372  CL103 HEK-293T C63(0.95); C93(1.03); C52(1.01); C216(0.89)  LDD1576  [25]
 LDCM0373  CL104 HEK-293T C63(0.99); C93(1.17); C52(1.01); C216(0.88)  LDD1577  [25]
 LDCM0374  CL105 HEK-293T C63(1.02); C93(1.08); C52(1.15); C216(0.94)  LDD1578  [25]
 LDCM0375  CL106 HEK-293T C63(1.02); C93(1.06); C52(0.89); C216(0.97)  LDD1579  [25]
 LDCM0376  CL107 HEK-293T C63(1.03); C93(1.00); C52(1.01); C216(0.99)  LDD1580  [25]
 LDCM0377  CL108 HEK-293T C63(0.92); C93(1.14); C52(1.10); C216(0.97)  LDD1581  [25]
 LDCM0378  CL109 HEK-293T C63(0.74); C93(1.13); C52(1.02); C216(0.95)  LDD1582  [25]
 LDCM0379  CL11 HEK-293T C63(0.96); C93(0.84); C52(1.01); C216(0.74)  LDD1583  [25]
 LDCM0380  CL110 HEK-293T C63(0.94); C93(0.99); C52(1.00); C216(0.92)  LDD1584  [25]
 LDCM0381  CL111 HEK-293T C63(0.92); C93(0.96); C52(0.93); C216(0.94)  LDD1585  [25]
 LDCM0382  CL112 HEK-293T C63(0.89); C93(1.03); C52(0.97); C216(0.95)  LDD1586  [25]
 LDCM0383  CL113 HEK-293T C63(1.00); C93(1.09); C52(1.03); C216(0.99)  LDD1587  [25]
 LDCM0384  CL114 HEK-293T C63(0.92); C93(1.04); C52(1.06); C216(0.89)  LDD1588  [25]
 LDCM0385  CL115 HEK-293T C63(0.98); C93(1.19); C52(1.04); C216(0.96)  LDD1589  [25]
 LDCM0386  CL116 HEK-293T C63(0.93); C93(1.13); C52(1.02); C216(0.95)  LDD1590  [25]
 LDCM0387  CL117 HEK-293T C63(0.97); C93(1.08); C52(1.01); C216(0.96)  LDD1591  [25]
 LDCM0388  CL118 HEK-293T C63(0.96); C93(1.05); C52(1.02); C216(0.87)  LDD1592  [25]
 LDCM0389  CL119 HEK-293T C63(0.97); C93(1.07); C52(1.05); C216(0.97)  LDD1593  [25]
 LDCM0390  CL12 HEK-293T C63(0.94); C93(0.98); C52(0.81); C216(0.81)  LDD1594  [25]
 LDCM0391  CL120 HEK-293T C63(0.97); C93(1.07); C52(0.99); C216(0.89)  LDD1595  [25]
 LDCM0392  CL121 HEK-293T C63(0.98); C93(1.08); C52(1.05); C216(0.96)  LDD1596  [25]
 LDCM0393  CL122 HEK-293T C63(1.06); C93(1.06); C52(1.01); C216(0.87)  LDD1597  [25]
 LDCM0394  CL123 HEK-293T C63(0.94); C93(1.03); C52(0.87); C216(0.82)  LDD1598  [25]
 LDCM0395  CL124 HEK-293T C63(0.88); C93(1.03); C52(0.92); C216(0.94)  LDD1599  [25]
 LDCM0396  CL125 HEK-293T C63(1.06); C93(1.15); C52(1.19); C216(1.02)  LDD1600  [25]
 LDCM0397  CL126 HEK-293T C63(0.99); C93(1.11); C52(1.02); C216(0.92)  LDD1601  [25]
 LDCM0398  CL127 HEK-293T C63(1.00); C93(1.23); C52(1.01); C216(1.03)  LDD1602  [25]
 LDCM0399  CL128 HEK-293T C63(0.91); C93(1.21); C52(1.09); C216(0.97)  LDD1603  [25]
 LDCM0400  CL13 HEK-293T C63(1.15); C93(0.96); C52(0.93); C216(0.87)  LDD1604  [25]
 LDCM0401  CL14 HEK-293T C63(1.06); C93(1.10); C52(1.03); C216(0.94)  LDD1605  [25]
 LDCM0402  CL15 HEK-293T C63(0.80); C93(0.86); C52(0.89); C216(0.85)  LDD1606  [25]
 LDCM0403  CL16 HEK-293T C63(0.91); C93(1.10); C52(0.96); C216(0.97)  LDD1607  [25]
 LDCM0404  CL17 HEK-293T C63(0.78); C93(0.77); C52(0.87); C216(0.91)  LDD1608  [25]
 LDCM0405  CL18 HEK-293T C63(1.04); C93(1.02); C52(1.09); C216(0.85)  LDD1609  [25]
 LDCM0406  CL19 HEK-293T C63(0.97); C93(0.91); C52(0.99); C216(0.95)  LDD1610  [25]
 LDCM0407  CL2 HEK-293T C63(1.03); C93(0.95); C52(0.93); C216(0.89)  LDD1611  [25]
 LDCM0408  CL20 HEK-293T C63(1.06); C93(0.84); C52(1.02); C216(0.94)  LDD1612  [25]
 LDCM0409  CL21 HEK-293T C63(1.10); C93(0.92); C52(1.07); C216(0.56)  LDD1613  [25]
 LDCM0410  CL22 HEK-293T C63(1.18); C93(0.99); C52(1.01); C216(1.05)  LDD1614  [25]
 LDCM0411  CL23 HEK-293T C63(1.08); C93(0.92); C52(1.02); C216(0.79)  LDD1615  [25]
 LDCM0412  CL24 HEK-293T C63(1.02); C93(0.91); C52(0.89); C216(0.81)  LDD1616  [25]
 LDCM0413  CL25 HEK-293T C63(0.90); C93(0.97); C52(1.05); C216(0.87)  LDD1617  [25]
 LDCM0414  CL26 HEK-293T C63(1.01); C93(1.01); C52(1.02); C216(0.94)  LDD1618  [25]
 LDCM0415  CL27 HEK-293T C63(0.94); C93(0.98); C52(1.03); C216(0.98)  LDD1619  [25]
 LDCM0416  CL28 HEK-293T C63(0.94); C93(0.96); C52(0.92); C216(0.89)  LDD1620  [25]
 LDCM0417  CL29 HEK-293T C63(0.95); C93(0.96); C52(1.11); C216(0.87)  LDD1621  [25]
 LDCM0418  CL3 HEK-293T C63(0.98); C93(0.97); C52(0.93); C216(0.92)  LDD1622  [25]
 LDCM0419  CL30 HEK-293T C63(0.98); C93(0.99); C52(1.07); C216(0.98)  LDD1623  [25]
 LDCM0420  CL31 HEK-293T C63(1.01); C93(0.87); C52(1.07); C216(0.89)  LDD1624  [25]
 LDCM0421  CL32 HEK-293T C63(1.08); C93(0.83); C52(0.97); C216(0.96)  LDD1625  [25]
 LDCM0422  CL33 HEK-293T C63(1.00); C93(0.87); C52(0.91); C216(0.57)  LDD1626  [25]
 LDCM0423  CL34 HEK-293T C63(1.26); C93(0.95); C52(0.93); C216(1.02)  LDD1627  [25]
 LDCM0424  CL35 HEK-293T C63(1.13); C93(0.92); C52(1.11); C216(0.82)  LDD1628  [25]
 LDCM0425  CL36 HEK-293T C63(1.14); C93(0.98); C52(0.88); C216(0.78)  LDD1629  [25]
 LDCM0426  CL37 HEK-293T C63(0.95); C93(1.08); C52(1.29); C216(0.92)  LDD1630  [25]
 LDCM0428  CL39 HEK-293T C63(0.97); C93(1.02); C52(0.96); C216(0.92)  LDD1632  [25]
 LDCM0429  CL4 HEK-293T C63(0.91); C93(1.04); C52(1.01); C216(0.94)  LDD1633  [25]
 LDCM0430  CL40 HEK-293T C63(0.98); C93(1.12); C52(1.07); C216(0.95)  LDD1634  [25]
 LDCM0431  CL41 HEK-293T C63(1.01); C93(1.04); C52(1.04); C216(1.00)  LDD1635  [25]
 LDCM0432  CL42 HEK-293T C63(0.97); C93(1.11); C52(1.00); C216(0.95)  LDD1636  [25]
 LDCM0433  CL43 HEK-293T C63(1.01); C93(1.05); C52(1.22); C216(0.88)  LDD1637  [25]
 LDCM0434  CL44 HEK-293T C63(0.99); C93(0.91); C52(1.08); C216(1.05)  LDD1638  [25]
 LDCM0435  CL45 HEK-293T C63(1.08); C93(0.89); C52(0.93); C216(0.66)  LDD1639  [25]
 LDCM0436  CL46 HEK-293T C63(1.16); C93(1.09); C52(0.96); C216(1.14)  LDD1640  [25]
 LDCM0437  CL47 HEK-293T C63(1.01); C93(0.96); C52(1.13); C216(0.82)  LDD1641  [25]
 LDCM0438  CL48 HEK-293T C63(1.19); C93(0.96); C52(0.93); C216(0.85)  LDD1642  [25]
 LDCM0439  CL49 HEK-293T C63(0.92); C93(1.14); C52(1.10); C216(0.92)  LDD1643  [25]
 LDCM0440  CL5 HEK-293T C63(0.97); C93(0.87); C52(0.93); C216(1.03)  LDD1644  [25]
 LDCM0441  CL50 HEK-293T C63(1.00); C93(1.02); C52(0.99); C216(0.92)  LDD1645  [25]
 LDCM0443  CL52 HEK-293T C63(1.00); C93(1.01); C52(1.03); C216(0.90)  LDD1646  [25]
 LDCM0444  CL53 HEK-293T C63(0.90); C93(0.91); C52(0.97); C216(0.84)  LDD1647  [25]
 LDCM0445  CL54 HEK-293T C63(0.85); C93(0.92); C52(0.95); C216(0.78)  LDD1648  [25]
 LDCM0446  CL55 HEK-293T C63(0.93); C93(0.94); C52(1.04); C216(0.97)  LDD1649  [25]
 LDCM0447  CL56 HEK-293T C63(1.03); C93(0.92); C52(1.08); C216(0.96)  LDD1650  [25]
 LDCM0448  CL57 HEK-293T C63(1.03); C93(0.93); C52(1.06); C216(0.57)  LDD1651  [25]
 LDCM0449  CL58 HEK-293T C63(1.07); C93(0.95); C52(0.97); C216(1.02)  LDD1652  [25]
 LDCM0450  CL59 HEK-293T C63(1.05); C93(0.98); C52(1.10); C216(0.87)  LDD1653  [25]
 LDCM0451  CL6 HEK-293T C63(1.01); C93(0.91); C52(0.92); C216(0.79)  LDD1654  [25]
 LDCM0452  CL60 HEK-293T C63(1.04); C93(0.94); C52(0.79); C216(0.74)  LDD1655  [25]
 LDCM0453  CL61 HEK-293T C63(0.95); C93(1.04); C52(1.08); C216(0.94)  LDD1656  [25]
 LDCM0454  CL62 HEK-293T C63(0.97); C93(1.03); C52(1.05); C216(0.92)  LDD1657  [25]
 LDCM0455  CL63 HEK-293T C63(0.93); C93(1.11); C52(0.97); C216(0.90)  LDD1658  [25]
 LDCM0456  CL64 HEK-293T C63(0.89); C93(1.01); C52(0.96); C216(0.85)  LDD1659  [25]
 LDCM0457  CL65 HEK-293T C63(0.96); C93(1.00); C52(1.09); C216(0.87)  LDD1660  [25]
 LDCM0458  CL66 HEK-293T C63(0.94); C93(1.00); C52(1.05); C216(0.85)  LDD1661  [25]
 LDCM0459  CL67 HEK-293T C63(0.98); C93(0.98); C52(1.07); C216(0.96)  LDD1662  [25]
 LDCM0460  CL68 HEK-293T C63(1.03); C93(0.98); C52(1.11); C216(0.90)  LDD1663  [25]
 LDCM0461  CL69 HEK-293T C63(1.05); C93(0.99); C52(1.08); C216(0.71)  LDD1664  [25]
 LDCM0462  CL7 HEK-293T C63(0.93); C93(0.89); C52(0.93); C216(0.95)  LDD1665  [25]
 LDCM0463  CL70 HEK-293T C63(1.16); C93(1.00); C52(1.02); C216(0.97)  LDD1666  [25]
 LDCM0464  CL71 HEK-293T C63(1.10); C93(0.96); C52(1.07); C216(0.88)  LDD1667  [25]
 LDCM0465  CL72 HEK-293T C63(1.04); C93(0.92); C52(1.22); C216(0.85)  LDD1668  [25]
 LDCM0466  CL73 HEK-293T C63(1.05); C93(1.10); C52(1.00); C216(0.93)  LDD1669  [25]
 LDCM0467  CL74 HEK-293T C63(1.08); C93(1.11); C52(1.11); C216(0.92)  LDD1670  [25]
 LDCM0469  CL76 HEK-293T C63(0.95); C93(1.05); C52(0.99); C216(0.89)  LDD1672  [25]
 LDCM0470  CL77 HEK-293T C63(0.89); C93(0.91); C52(0.95); C216(0.88)  LDD1673  [25]
 LDCM0471  CL78 HEK-293T C63(0.98); C93(1.08); C52(1.05); C216(0.87)  LDD1674  [25]
 LDCM0472  CL79 HEK-293T C63(0.94); C93(1.05); C52(1.10); C216(0.87)  LDD1675  [25]
 LDCM0473  CL8 HEK-293T C63(0.75); C93(0.79); C52(1.02); C216(0.66)  LDD1676  [25]
 LDCM0474  CL80 HEK-293T C63(0.94); C93(1.04); C52(1.12); C216(0.98)  LDD1677  [25]
 LDCM0475  CL81 HEK-293T C63(1.07); C93(0.95); C52(1.05); C216(0.75)  LDD1678  [25]
 LDCM0476  CL82 HEK-293T C63(1.01); C93(1.08); C52(0.97); C216(1.00)  LDD1679  [25]
 LDCM0477  CL83 HEK-293T C63(1.01); C93(1.06); C52(1.03); C216(0.89)  LDD1680  [25]
 LDCM0478  CL84 HEK-293T C63(0.97); C93(1.05); C52(0.82); C216(0.90)  LDD1681  [25]
 LDCM0479  CL85 HEK-293T C63(1.01); C93(1.14); C52(1.13); C216(0.94)  LDD1682  [25]
 LDCM0480  CL86 HEK-293T C63(0.99); C93(1.10); C52(1.00); C216(0.94)  LDD1683  [25]
 LDCM0481  CL87 HEK-293T C63(0.93); C93(1.12); C52(1.00); C216(0.88)  LDD1684  [25]
 LDCM0482  CL88 HEK-293T C63(0.97); C93(1.11); C52(1.00); C216(0.95)  LDD1685  [25]
 LDCM0483  CL89 HEK-293T C63(0.98); C93(1.02); C52(1.05); C216(1.00)  LDD1686  [25]
 LDCM0484  CL9 HEK-293T C63(1.11); C93(0.90); C52(0.95); C216(0.66)  LDD1687  [25]
 LDCM0485  CL90 HEK-293T C63(0.75); C93(0.83); C52(0.80); C216(0.65)  LDD1688  [25]
 LDCM0486  CL91 HEK-293T C63(0.88); C93(1.07); C52(1.02); C216(0.81)  LDD1689  [25]
 LDCM0487  CL92 HEK-293T C63(0.84); C93(1.01); C52(0.98); C216(0.87)  LDD1690  [25]
 LDCM0488  CL93 HEK-293T C63(1.00); C93(1.02); C52(1.04); C216(0.78)  LDD1691  [25]
 LDCM0489  CL94 HEK-293T C63(0.92); C93(1.04); C52(1.10); C216(0.98)  LDD1692  [25]
 LDCM0490  CL95 HEK-293T C63(1.00); C93(0.88); C52(0.97); C216(0.83)  LDD1693  [25]
 LDCM0491  CL96 HEK-293T C63(1.01); C93(1.05); C52(0.96); C216(0.95)  LDD1694  [25]
 LDCM0492  CL97 HEK-293T C63(0.82); C93(1.01); C52(0.99); C216(0.95)  LDD1695  [25]
 LDCM0493  CL98 HEK-293T C63(0.97); C93(1.06); C52(0.95); C216(0.90)  LDD1696  [25]
 LDCM0494  CL99 HEK-293T C63(0.95); C93(1.15); C52(0.91); C216(0.85)  LDD1697  [25]
 LDCM0495  E2913 HEK-293T C63(0.91); C93(1.08); C52(0.96); C216(0.88)  LDD1698  [25]
 LDCM0625  F8 Ramos C295(1.74); C63(1.16); C113(2.66)  LDD2187  [27]
 LDCM0572  Fragment10 Ramos C295(2.22); C63(1.13)  LDD2189  [27]
 LDCM0573  Fragment11 Ramos C295(0.33); C63(0.36); C113(20.00)  LDD2190  [27]
 LDCM0574  Fragment12 Ramos C295(1.10); C63(1.16)  LDD2191  [27]
 LDCM0575  Fragment13 Ramos C295(1.10); C63(1.06)  LDD2192  [27]
 LDCM0576  Fragment14 Ramos C295(0.77); C63(0.89); C113(1.05)  LDD2193  [27]
 LDCM0579  Fragment20 Ramos C295(1.39); C63(0.92)  LDD2194  [27]
 LDCM0580  Fragment21 Ramos C295(0.94); C63(1.18)  LDD2195  [27]
 LDCM0582  Fragment23 Ramos C295(0.89); C63(1.40)  LDD2196  [27]
 LDCM0578  Fragment27 Ramos C295(0.88); C63(1.03)  LDD2197  [27]
 LDCM0586  Fragment28 Ramos C295(0.93); C63(0.73); C113(0.15)  LDD2198  [27]
 LDCM0588  Fragment30 Ramos C295(1.38); C63(1.32)  LDD2199  [27]
 LDCM0589  Fragment31 Ramos C295(0.87); C63(1.04)  LDD2200  [27]
 LDCM0590  Fragment32 Ramos C295(3.76); C63(0.85)  LDD2201  [27]
 LDCM0468  Fragment33 HEK-293T C63(0.98); C93(1.17); C52(1.04); C216(0.92)  LDD1671  [25]
 LDCM0596  Fragment38 Ramos C295(0.96); C63(0.91)  LDD2203  [27]
 LDCM0566  Fragment4 Ramos C295(1.18); C63(0.87); C113(0.45)  LDD2184  [27]
 LDCM0427  Fragment51 HEK-293T C63(0.96); C93(1.04); C52(1.07); C216(1.03)  LDD1631  [25]
 LDCM0610  Fragment52 Ramos C295(1.21); C63(1.14)  LDD2204  [27]
 LDCM0614  Fragment56 Ramos C295(1.31); C63(1.09)  LDD2205  [27]
 LDCM0569  Fragment7 Ramos C295(1.32); C63(1.48); C113(0.54)  LDD2186  [27]
 LDCM0571  Fragment9 Ramos C295(1.08); C63(0.95)  LDD2188  [27]
 LDCM0116  HHS-0101 DM93 Y147(0.79); Y258(0.86)  LDD0264  [8]
 LDCM0117  HHS-0201 DM93 Y147(0.66); Y258(0.74)  LDD0265  [8]
 LDCM0118  HHS-0301 DM93 Y258(0.57); Y147(1.54)  LDD0266  [8]
 LDCM0119  HHS-0401 DM93 Y258(0.92)  LDD0267  [8]
 LDCM0120  HHS-0701 DM93 Y258(0.84); Y147(1.34)  LDD0268  [8]
 LDCM0107  IAA HeLa C63(0.00); C220(0.00); H270(0.00)  LDD0221  [17]
 LDCM0022  KB02 HEK-293T C63(1.03); C93(0.95); C52(0.97); C216(0.81)  LDD1492  [25]
 LDCM0023  KB03 HEK-293T C63(1.03); C93(0.98); C52(1.03); C216(1.15)  LDD1497  [25]
 LDCM0024  KB05 HMCB C52(4.06); C93(2.22)  LDD3312  [6]
 LDCM0109  NEM HeLa N.A.  LDD0223  [17]
 LDCM0496  Nucleophilic fragment 11a MDA-MB-231 C295(0.46); C63(0.99)  LDD2089  [4]
 LDCM0497  Nucleophilic fragment 11b MDA-MB-231 C295(1.52)  LDD2090  [4]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C113(1.13)  LDD2093  [4]
 LDCM0501  Nucleophilic fragment 13b MDA-MB-231 C295(1.14)  LDD2094  [4]
 LDCM0503  Nucleophilic fragment 14b MDA-MB-231 C113(0.63)  LDD2096  [4]
 LDCM0505  Nucleophilic fragment 15b MDA-MB-231 C295(1.01)  LDD2098  [4]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C113(1.31); C63(1.70)  LDD2099  [4]
 LDCM0507  Nucleophilic fragment 16b MDA-MB-231 C113(1.36)  LDD2100  [4]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C113(0.88)  LDD2101  [4]
 LDCM0511  Nucleophilic fragment 18b MDA-MB-231 C113(0.97); C295(1.14)  LDD2104  [4]
 LDCM0512  Nucleophilic fragment 19a MDA-MB-231 C295(1.36)  LDD2105  [4]
 LDCM0513  Nucleophilic fragment 19b MDA-MB-231 C113(1.38)  LDD2106  [4]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C113(1.12); C63(0.96)  LDD2107  [4]
 LDCM0515  Nucleophilic fragment 20b MDA-MB-231 C113(0.48); C295(0.79); C216(0.84)  LDD2108  [4]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C113(0.73); C63(1.04)  LDD2109  [4]
 LDCM0517  Nucleophilic fragment 21b MDA-MB-231 C113(0.85)  LDD2110  [4]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C113(1.06)  LDD2111  [4]
 LDCM0521  Nucleophilic fragment 23b MDA-MB-231 C295(0.88)  LDD2114  [4]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C113(0.59)  LDD2115  [4]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C113(0.89); C295(0.24)  LDD2116  [4]
 LDCM0525  Nucleophilic fragment 25b MDA-MB-231 C113(1.22)  LDD2118  [4]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C113(2.03); C295(3.35)  LDD2119  [4]
 LDCM0529  Nucleophilic fragment 27b MDA-MB-231 C113(0.54); C295(0.25)  LDD2122  [4]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C113(0.80); C63(1.21)  LDD2123  [4]
 LDCM0531  Nucleophilic fragment 28b MDA-MB-231 C113(0.59); C295(0.16)  LDD2124  [4]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C113(0.94); C63(1.04)  LDD2125  [4]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C113(1.42); C295(0.17)  LDD2126  [4]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C113(1.16); C63(1.16)  LDD2127  [4]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C113(0.96)  LDD2129  [4]
 LDCM0540  Nucleophilic fragment 35 MDA-MB-231 C113(0.47)  LDD2133  [4]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C113(0.60); C63(0.55)  LDD2134  [4]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C113(1.05); C295(0.63); C63(1.17)  LDD2135  [4]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C113(1.21)  LDD2136  [4]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C113(0.92); C63(1.33)  LDD2137  [4]
 LDCM0211  Nucleophilic fragment 3b MDA-MB-231 C113(2.47)  LDD1700  [4]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C113(1.06)  LDD2140  [4]
 LDCM0547  Nucleophilic fragment 41 MDA-MB-231 C113(1.40)  LDD2141  [4]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C113(2.23)  LDD2144  [4]
 LDCM0551  Nucleophilic fragment 5b MDA-MB-231 C295(3.45)  LDD2145  [4]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C113(0.85)  LDD2146  [4]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C113(0.41)  LDD2148  [4]
 LDCM0555  Nucleophilic fragment 7b MDA-MB-231 C113(0.97); C295(0.20)  LDD2149  [4]
 LDCM0556  Nucleophilic fragment 8a MDA-MB-231 C113(0.40); C63(0.64)  LDD2150  [4]
 LDCM0557  Nucleophilic fragment 8b MDA-MB-231 C113(0.61); C295(0.39)  LDD2151  [4]
 LDCM0627  NUDT7-COV-1 HEK-293T C295(0.80); C216(0.47)  LDD2206  [28]
 LDCM0628  OTUB2-COV-1 HEK-293T C216(2.32); C295(1.07); C295(0.36)  LDD2207  [28]
 LDCM0131  RA190 MM1.R C63(1.49); C216(1.24)  LDD0304  [29]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
RNA transcription, translation and transport factor protein (RTRAF) RTRAF family Q9Y224

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.
3 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
4 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
5 An Azo Coupling-Based Chemoproteomic Approach to Systematically Profile the Tyrosine Reactivity in the Human Proteome. Anal Chem. 2021 Jul 27;93(29):10334-10342. doi: 10.1021/acs.analchem.1c01935. Epub 2021 Jul 12.
6 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
7 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
8 Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29.
9 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
10 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
11 SP3-FAIMS Chemoproteomics for High-Coverage Profiling of the Human Cysteinome*. Chembiochem. 2021 May 14;22(10):1841-1851. doi: 10.1002/cbic.202000870. Epub 2021 Feb 18.
Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
12 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
13 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
14 Multiplexed CuAAC Suzuki-Miyaura Labeling for Tandem Activity-Based Chemoproteomic Profiling. Anal Chem. 2021 Feb 2;93(4):2610-2618. doi: 10.1021/acs.analchem.0c04726. Epub 2021 Jan 20.
Mass spectrometry data entry: PXD022279
15 DFT-Guided Discovery of Ethynyl-Triazolyl-Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling. Angew Chem Int Ed Engl. 2022 Oct 10;61(41):e202205348. doi: 10.1002/anie.202205348. Epub 2022 Aug 22.
Mass spectrometry data entry: PXD033004
16 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
17 ACR-Based Probe for the Quantitative Profiling of Histidine Reactivity in the Human Proteome. J Am Chem Soc. 2023 Mar 8;145(9):5252-5260. doi: 10.1021/jacs.2c12653. Epub 2023 Feb 27.
18 Oxidant-Induced Bioconjugation for Protein Labeling in Live Cells. ACS Chem Biol. 2023 Jan 20;18(1):112-122. doi: 10.1021/acschembio.2c00740. Epub 2022 Dec 21.
19 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
20 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
21 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
22 Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. 2017 Jan 26;168(3):527-541.e29. doi: 10.1016/j.cell.2016.12.029. Epub 2017 Jan 19.
23 Design and synthesis of minimalist terminal alkyne-containing diazirine photo-crosslinkers and their incorporation into kinase inhibitors for cell- and tissue-based proteome profiling. Angew Chem Int Ed Engl. 2013 Aug 12;52(33):8551-6. doi: 10.1002/anie.201300683. Epub 2013 Jun 10.
24 Pharmacological Targeting of Vacuolar H(+)-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chem Biol. 2020 Nov 19;27(11):1359-1370.e8. doi: 10.1016/j.chembiol.2020.06.011. Epub 2020 Jul 9.
25 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
26 Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chem Biol. 2019 Nov 15;14(11):2430-2440. doi: 10.1021/acschembio.8b01083. Epub 2019 May 13.
27 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
28 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.
29 Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.