Details of the Probe-central Interaction Altas
General Information of Experiment
| Probe Name | C207 | Probe Info | ||||
|---|---|---|---|---|---|---|
| Probe concentration | Probe:50uM; negative probe:50uM | |||||
| Criteria | Quantification: AfBPP Probe vs Negative Probe | |||||
| Quantitative Method |
TMT
|
|||||
| In Vivo Experiment Model | Model Type |
|
Living cell | |||
| Derived Tissue |
|
Peripheral blood | ||||
| Disease Model | Normal | |||||
| Model Name | Human normal cells (HEK-293T) | |||||
| Note | Negative probe:C#CCCC1(CCC(NC)=O)N=N1 | |||||
Interaction Altas of This Experiment [1]
Enzyme
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP00697 | Cytochrome b5 type B (CYB5B) | 67.2 | ||||
| LDTP00486 | Cytochrome b-c1 complex subunit 8 (UQCRQ) | 51.6 | ||||
| LDTP08933 | Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (CSGALNACT2) | 47.2 | ||||
| LDTP00832 | NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) | 46.2 | ||||
| LDTP03540 | Heme oxygenase 2 (HMOX2) | 34.1 | ||||
| LDTP06648 | Lanosterol 14-alpha demethylase (CYP51A1) | 24.4 | ||||
| LDTP02175 | Epoxide hydrolase 1 (EPHX1) | 24.3 | ||||
| LDTP06477 | Methylsterol monooxygenase 1 (MSMO1) | 24.1 | ||||
| LDTP06787 | Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) | 23.3 | ||||
| LDTP13189 | Cytochrome b-c1 complex subunit 9 (UQCR10) | 23.1 | ||||
| LDTP08790 | Mitochondrial cardiolipin hydrolase (PLD6) | 22.2 | ||||
| LDTP06150 | DNA replication licensing factor MCM6 (MCM6) | 21.6 | ||||
| LDTP04437 | Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) | 21.4 | ||||
| LDTP11055 | Telomerase RNA component interacting RNase (TRIR) | 20.3 | ||||
| LDTP03779 | Copper-transporting ATPase 2 (ATP7B) | 19.7 | ||||
| LDTP01065 | E3 ubiquitin-protein ligase TRIM13 (TRIM13) | 19.0 | ||||
| LDTP11178 | Chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) | 18.1 | ||||
| LDTP01613 | Sphingosine-1-phosphate lyase 1 (SGPL1) | 18.0 | ||||
Transporter and channel
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP01059 | Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) | 85.6 | ||||
| LDTP11813 | Solute carrier family 25 member 32 (SLC25A32) | 47.2 | ||||
| LDTP02724 | Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) | 41.9 | ||||
| LDTP03132 | Voltage-dependent anion-selective channel protein 1 (VDAC1) | 38.6 | ||||
| LDTP13983 | Mitochondrial import inner membrane translocase subunit TIM16 (PAM16) | 38.3 | ||||
| LDTP11162 | Solute carrier family 25 member 33 (SLC25A33) | 36.5 | ||||
| LDTP04071 | Voltage-dependent anion-selective channel protein 2 (VDAC2) | 35.0 | ||||
| LDTP10669 | Melanoma inhibitory activity protein 2 (MIA2) | 33.4 | ||||
| LDTP04033 | Translocon-associated protein subunit alpha (SSR1) | 33.4 | ||||
| LDTP15948 | Transmembrane protein 126A (TMEM126A) | 31.1 | ||||
| LDTP00562 | Membrane-associated progesterone receptor component 2 (PGRMC2) | 26.5 | ||||
| LDTP00541 | NPC intracellular cholesterol transporter 1 (NPC1) | 26.5 | ||||
| LDTP03277 | ER lumen protein-retaining receptor 1 (KDELR1) | 24.6 | ||||
| LDTP00547 | Secretory carrier-associated membrane protein 2 (SCAMP2) | 23.3 | ||||
| LDTP08881 | Transmembrane protein 199 (TMEM199) | 22.9 | ||||
| LDTP11095 | Mitochondrial 2-oxodicarboxylate carrier (SLC25A21) | 22.2 | ||||
| LDTP07236 | Protein GPR107 (GPR107) | 21.3 | ||||
| LDTP08981 | Cytochrome c oxidase assembly protein COX18, mitochondrial (COX18) | 20.5 | ||||
| LDTP05511 | Cytoskeleton-associated protein 4 (CKAP4) | 19.6 | ||||
| LDTP03284 | ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) | 18.9 | ||||
| LDTP18448 | Transmembrane 9 superfamily member 3 (TM9SF3) | 18.4 | ||||
Transcription factor
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP13718 | Zinc finger CCCH domain-containing protein 4 (ZC3H4) | 18.6 | ||||
Other
| Target ID | Target Name | Binding Ratio | ||||
|---|---|---|---|---|---|---|
| LDTP15067 | Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) | 43.4 | ||||
| LDTP01522 | Reticulon-3 (RTN3) | 40.2 | ||||
| LDTP13086 | Syntaxin-18 (STX18) | 29.9 | ||||
| LDTP12412 | Reticulon-4 (RTN4) | 26.7 | ||||
| LDTP08594 | Negative elongation factor C/D (NELFCD) | 22.2 | ||||
| LDTP10255 | Protein Hook homolog 2 (HOOK2) | 21.9 | ||||
| LDTP17229 | G patch domain-containing protein 4 (GPATCH4) | 21.7 | ||||
| LDTP12755 | OCIA domain-containing protein 1 (OCIAD1) | 21.7 | ||||
| LDTP04595 | Activated RNA polymerase II transcriptional coactivator p15 (SUB1) | 20.5 | ||||
| LDTP04425 | Translocon-associated protein subunit delta (SSR4) | 20.1 | ||||
| LDTP05778 | Chromobox protein homolog 3 (CBX3) | 20.0 | ||||
| LDTP16080 | Protein FAM114A2 (FAM114A2) | 20.0 | ||||
| LDTP10242 | Ribosome-recycling factor, mitochondrial (MRRF) | 19.2 | ||||
| LDTP12565 | Mitochondrial import receptor subunit TOM22 homolog (TOMM22) | 18.9 | ||||
| LDTP01494 | Protein YIF1A (YIF1A) | 18.6 | ||||
| LDTP03545 | Alpha-2-macroglobulin receptor-associated protein (LRPAP1) | 18.1 | ||||
| LDTP04073 | Chromobox protein homolog 5 (CBX5) | 18.1 | ||||
| LDTP06879 | Protein FAM98B (FAM98B) | 17.9 | ||||