Details of the Probe

General Information of Probe

Probe ID
LDPC0428
Probe Name
C191
Synonyms
Z3397334394
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 361.4
Lipid-water partition coefficient (xlogp) 0.8
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C20H19N5O2
IUPAC Name
1'-[3-(3-but-3-ynyldiazirin-3-yl)propanoyl]-2-oxospiro[1H-indole-3,4'-pyrrolidine]-3'-carbonitrile
Canonical SMILES
C#CCCC1(N=N1)CCC(=O)N2CC(C3(C2)C4=CC=CC=C4NC3=O)C#N
InChI
InChI=1S/C20H19N5O2/c1-2-3-9-19(23-24-19)10-8-17(26)25-12-14(11-21)20(13-25)15-6-4-5-7-16(15)22-18(20)27/h1,4-7,14H,3,8-10,12-13H2,(H,22,27)
InChIKey
DRNAAQMFHMHWAZ-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

108 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
14 kDa phosphohistidine phosphatase (PHPT1) LDTP12543 10.41  LDD1868 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 11.24  LDD1868 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 12.64  LDD1868 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 9.65  LDD1868 
Adenosine kinase (ADK) LDTP04689 11.47  LDD1868 
AFG3-like protein 2 (AFG3L2) LDTP14075 10.85  LDD1868 
Aldehyde dehydrogenase family 3 member A2 (ALDH3A2) LDTP04437 9.78  LDD1868 
Amidophosphoribosyltransferase (PPAT) LDTP05480 32.00  LDD1868 
AMP deaminase 2 (AMPD2) LDTP05289 11.55  LDD1868 
Apoptosis-inducing factor 1, mitochondrial (AIFM1) LDTP01687 11.31  LDD1868 
ATP-dependent translocase ABCB1 (ABCB1) LDTP02254 17.51  LDD1868 
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (MTHFD2) LDTP02706 12.38  LDD1868 
CAAX prenyl protease 1 homolog (ZMPSTE24) LDTP01328 23.59  LDD1868 
Calcyclin-binding protein (CACYBP) LDTP12163 9.65  LDD1868 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 9.92  LDD1868 
Carboxymethylenebutenolidase homolog (CMBL) LDTP10215 35.75  LDD1868 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 9.51  LDD1868 
CCR4-NOT transcription complex subunit 4 (CNOT4) LDTP01640 26.72  LDD1868 
Ceramide synthase 1 (CERS1) LDTP03394 14.83  LDD1868 
Ceramide synthase 2 (CERS2) LDTP10329 9.85  LDD1868 
COP9 signalosome complex subunit 4 (COPS4) LDTP11187 13.55  LDD1868 
CTP synthase 1 (CTPS1) LDTP02922 12.21  LDD1868 
Cytochrome b-c1 complex subunit 9 (UQCR10) LDTP13189 57.28  LDD1868 
Cytochrome b5 type B (CYB5B) LDTP00697 22.78  LDD1868 
Cytochrome c oxidase assembly factor 7 (COA7) LDTP10137 16.22  LDD1868 
Cytochrome P450 20A1 (CYP20A1) LDTP17410 14.03  LDD1868 
DCN1-like protein 5 (DCUN1D5) LDTP11199 11.08  LDD1868 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 15.45  LDD1868 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 9.65  LDD1868 
Delta(24)-sterol reductase (DHCR24) LDTP06375 31.78  LDD1868 
Dermatan-sulfate epimerase (DSE) LDTP13504 11.47  LDD1868 
Dihydrofolate reductase (DHFR) LDTP01769 14.32  LDD1868 
Dihydropteridine reductase (QDPR) LDTP02342 25.99  LDD1868 
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (STT3B) LDTP09388 10.34  LDD1868 
Dolichyl-phosphate beta-glucosyltransferase (ALG5) LDTP14214 10.48  LDD1868 
E3 ubiquitin-protein ligase ARIH1 (ARIH1) LDTP14079 12.13  LDD1868 
E3 ubiquitin-protein ligase RNF114 (RNF114) LDTP14083 19.56  LDD1868 
E3 ubiquitin-protein ligase TRIM21 (TRIM21) LDTP03001 14.72  LDD1868 
Endonuclease domain-containing 1 protein (ENDOD1) LDTP01462 9.51  LDD1868 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 11.31  LDD1868 
Endoplasmic reticulum protein SC65 (P3H4) LDTP09874 13.18  LDD1868 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 12.73  LDD1868 
Epoxide hydrolase 1 (EPHX1) LDTP02175 10.20  LDD1868 
Exonuclease 1 (EXO1) LDTP13751 9.71  LDD1868 
Farnesyl pyrophosphate synthase (FDPS) LDTP02721 9.85  LDD1868 
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) LDTP12253 16.56  LDD1868 
Glycogen synthase kinase-3 alpha (GSK3A) LDTP04318 15.56  LDD1868 
GPI-anchor transamidase (PIGK) LDTP09835 11.16  LDD1868 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 10.34  LDD1868 
Helicase MOV-10 (MOV10) LDTP12233 13.83  LDD1868 
Heme oxygenase 1 (HMOX1) LDTP02359 11.08  LDD1868 
Heme oxygenase 2 (HMOX2) LDTP03540 21.26  LDD1868 
Histone-lysine N-methyltransferase SMYD3 (SMYD3) LDTP12020 11.63  LDD1868 
Holocytochrome c-type synthase (HCCS) LDTP04581 29.86  LDD1868 
Hydroxysteroid dehydrogenase-like protein 2 (HSDL2) LDTP07762 9.51  LDD1868 
Inactive hydroxysteroid dehydrogenase-like protein 1 (HSDL1) LDTP06787 16.91  LDD1868 
Isochorismatase domain-containing protein 1 (ISOC1) LDTP19851 11.39  LDD1868 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 25.81  LDD1868 
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) LDTP04211 17.15  LDD1868 
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3A) LDTP04345 10.34  LDD1868 
Kinesin-like protein KIF20A (KIF20A) LDTP01535 13.18  LDD1868 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 11.55  LDD1868 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 12.30  LDD1868 
Lysocardiolipin acyltransferase 1 (LCLAT1) LDTP07679 13.27  LDD1868 
Lysophosphatidic acid phosphatase type 6 (ACP6) LDTP12363 11.55  LDD1868 
Lysophospholipid acyltransferase 7 (MBOAT7) LDTP10612 34.06  LDD1868 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 10.06  LDD1868 
Mitochondrial coenzyme A diphosphatase NUDT8 (NUDT8) LDTP09598 10.34  LDD1868 
Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1) LDTP00837 30.27  LDD1868 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 9.58  LDD1868 
NAD-capped RNA hydrolase NUDT12 (NUDT12) LDTP11081 61.39  LDD1868 
NADH dehydrogenase 1 beta subcomplex subunit 4 (NDUFB4) LDTP01514 11.71  LDD1868 
NADH-cytochrome b5 reductase 1 (CYB5R1) LDTP13303 11.55  LDD1868 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 9.65  LDD1868 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 38.32  LDD1868 
Obg-like ATPase 1 (OLA1) LDTP12610 30.48  LDD1868 
Peptidyl-prolyl cis-trans isomerase FKBP14 (FKBP14) LDTP12720 13.45  LDD1868 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 11.63  LDD1868 
Polypeptide N-acetylgalactosaminyltransferase 1 (GALNT1) LDTP05624 22.01  LDD1868 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 20.53  LDD1868 
Presequence protease, mitochondrial (PITRM1) LDTP07003 25.11  LDD1868 
Prolyl 3-hydroxylase 1 (P3H1) LDTP06750 12.30  LDD1868 
Prolyl 4-hydroxylase subunit alpha-1 (P4HA1) LDTP02679 10.63  LDD1868 
Prolyl 4-hydroxylase subunit alpha-2 (P4HA2) LDTP00645 14.42  LDD1868 
Prostaglandin reductase 3 (PTGR3) LDTP15422 37.79  LDD1868 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 18.25  LDD1868 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 12.30  LDD1868 
Protein O-GlcNAcase (OGA) LDTP00988 18.51  LDD1868 
Protein phosphatase 3 catalytic subunit alpha (PPP3CA) LDTP05549 12.38  LDD1868 
Protein SCO2 homolog, mitochondrial (SCO2) LDTP00877 11.96  LDD1868 
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT1) LDTP03152 9.99  LDD1868 
Protein-S-isoprenylcysteine O-methyltransferase (ICMT) LDTP01039 18.77  LDD1868 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 10.93  LDD1868 
Putative peptidyl-tRNA hydrolase PTRHD1 (PTRHD1) LDTP19478 12.13  LDD1868 
Ras-related protein Rab-1A (RAB1A) LDTP05006 99.73  LDD1868 
Ribonuclease H2 subunit A (RNASEH2A) LDTP01311 18.25  LDD1868 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 14.52  LDD1868 
Septin-6 (SEPTIN6) LDTP06049 9.92  LDD1868 
Signal peptidase complex catalytic subunit SEC11A (SEC11A) LDTP05066 10.78  LDD1868 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 10.34  LDD1868 
Telomerase RNA component interacting RNase (TRIR) LDTP11055 12.47  LDD1868 
Thioredoxin-related transmembrane protein 1 (TMX1) LDTP11874 11.31  LDD1868 
Thiosulfate sulfurtransferase (TST) LDTP06620 11.00  LDD1868 
Translation initiation factor IF-2, mitochondrial (MTIF2) LDTP04093 9.78  LDD1868 
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) LDTP03912 11.24  LDD1868 
Tumor susceptibility gene 101 protein (TSG101) LDTP10987 12.21  LDD1868 
Ubiquitin-protein ligase E3A (UBE3A) LDTP05446 13.00  LDD1868 
Xaa-Arg dipeptidase (PM20D2) LDTP08666 11.47  LDD1868 
------------------------------------------------------------------------------------
⏷ Show the Full List of 108 Enzyme
56 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
14-3-3 protein epsilon (YWHAE) LDTP04969 9.92  LDD1868 
14-3-3 protein theta (YWHAQ) LDTP03385 10.41  LDD1868 
45 kDa calcium-binding protein (SDF4) LDTP11116 12.55  LDD1868 
Anion exchange protein 2 (SLC4A2) LDTP02061 9.58  LDD1868 
ATP synthase F(0) complex subunit B1, mitochondrial (ATP5PB) LDTP03284 13.18  LDD1868 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 17.75  LDD1868 
Battenin (CLN3) LDTP05814 18.64  LDD1868 
Ceramide transfer protein (CERT1) LDTP14140 34.06  LDD1868 
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1) LDTP02645 19.03  LDD1868 
Cytochrome c oxidase subunit 7A2, mitochondrial (COX7A2) LDTP02724 20.68  LDD1868 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 12.82  LDD1868 
Erlin-2 (ERLIN2) LDTP01455 9.99  LDD1868 
Exocyst complex component 2 (EXOC2) LDTP10513 15.24  LDD1868 
Exocyst complex component 8 (EXOC8) LDTP08651 12.73  LDD1868 
Golgin subfamily A member 5 (GOLGA5) LDTP09333 12.38  LDD1868 
H(+)/Cl(-) exchange transporter 6 (CLCN6) LDTP04462 10.70  LDD1868 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 11.63  LDD1868 
Importin subunit alpha-5 (KPNA1) LDTP04502 17.88  LDD1868 
Importin subunit alpha-7 (KPNA6) LDTP01031 20.53  LDD1868 
Magnesium transporter NIPA3 (NIPAL1) LDTP17362 20.53  LDD1868 
Major facilitator superfamily domain-containing protein 3 (MFSD3) LDTP18153 14.83  LDD1868 
Membrane-associated progesterone receptor component 1 (PGRMC1) LDTP00235 11.63  LDD1868 
Membrane-associated progesterone receptor component 2 (PGRMC2) LDTP00562 13.09  LDD1868 
MICOS complex subunit MIC60 (IMMT) LDTP06660 9.78  LDD1868 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 14.93  LDD1868 
Mitochondrial dicarboxylate carrier (SLC25A10) LDTP13174 13.36  LDD1868 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 45.57  LDD1868 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 20.82  LDD1868 
Mitochondrial inner membrane protein OXA1L (OXA1L) LDTP06308 18.25  LDD1868 
Mitochondrial ornithine transporter 1 (SLC25A15) LDTP14200 10.48  LDD1868 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 47.84  LDD1868 
Monocarboxylate transporter 1 (SLC16A1) LDTP04592 14.62  LDD1868 
Mpv17-like protein 2 (MPV17L2) LDTP14952 17.27  LDD1868 
Nucleoporin NDC1 (NDC1) LDTP11213 14.22  LDD1868 
Peroxisomal biogenesis factor 19 (PEX19) LDTP03905 27.47  LDD1868 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 25.81  LDD1868 
Protein ERGIC-53 (LMAN1) LDTP04237 44.32  LDD1868 
Protein tweety homolog 3 (TTYH3) LDTP11615 12.64  LDD1868 
Putative lipid scramblase CLPTM1 (CLPTM1) LDTP01745 17.15  LDD1868 
Reduced folate transporter (SLC19A1) LDTP03952 10.27  LDD1868 
Sideroflexin-1 (SFXN1) LDTP12090 10.48  LDD1868 
Signal recognition particle 14 kDa protein (SRP14) LDTP03837 9.58  LDD1868 
Solute carrier family 25 member 32 (SLC25A32) LDTP11813 33.13  LDD1868 
Solute carrier family 25 member 33 (SLC25A33) LDTP11162 9.92  LDD1868 
SUN domain-containing protein 1 (SUN1) LDTP01454 10.27  LDD1868 
Tetraspanin-10 (TSPAN10) LDTP15967 14.03  LDD1868 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 21.71  LDD1868 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 46.85  LDD1868 
Transmembrane emp24 domain-containing protein 7 (TMED7) LDTP13969 9.58  LDD1868 
Transmembrane protein 126A (TMEM126A) LDTP15948 16.80  LDD1868 
Transmembrane protein 205 (TMEM205) LDTP07667 11.55  LDD1868 
Transportin-1 (TNPO1) LDTP09949 23.43  LDD1868 
Vacuolar protein sorting-associated protein 29 (VPS29) LDTP13142 9.78  LDD1868 
Vesicle-associated membrane protein-associated protein A (VAPA) LDTP12966 9.92  LDD1868 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 11.16  LDD1868 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 17.51  LDD1868 
------------------------------------------------------------------------------------
⏷ Show the Full List of 56 Transporter and channel
8 Transcription factor Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
CDKN2A-interacting protein (CDKN2AIP) LDTP12792 10.41  LDD1868 
Forkhead box protein K1 (FOXK1) LDTP05201 9.99  LDD1868 
High mobility group protein B1 (HMGB1) LDTP02343 15.56  LDD1868 
High mobility group protein B3 (HMGB3) LDTP00612 10.63  LDD1868 
Homeobox protein SIX4 (SIX4) LDTP13361 11.55  LDD1868 
Non-POU domain-containing octamer-binding protein (NONO) LDTP06341 17.39  LDD1868 
PHD finger-like domain-containing protein 5A (PHF5A) LDTP08006 35.51  LDD1868 
Transcriptional repressor p66-alpha (GATAD2A) LDTP08409 14.12  LDD1868 
------------------------------------------------------------------------------------
⏷ Show the Full List of 8 Transcription factor
1 GPCR Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Membrane progestin receptor alpha (PAQR7) LDTP15303 46.21  LDD1868 
------------------------------------------------------------------------------------
1 Immunoglobulin Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
HLA class I histocompatibility antigen, alpha chain E (HLA-E) LDTP02688 32.45  LDD1868 
------------------------------------------------------------------------------------
174 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
14-3-3 protein eta (YWHAH) LDTP05442 11.88  LDD1868 
17S U2 SnRNP complex component HTATSF1 (HTATSF1) LDTP00849 10.13  LDD1868 
A-kinase anchor protein 8 (AKAP8) LDTP00880 11.39  LDD1868 
ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) LDTP08950 14.62  LDD1868 
Alpha-2-macroglobulin receptor-associated protein (LRPAP1) LDTP03545 10.06  LDD1868 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 20.82  LDD1868 
Apolipoprotein L2 (APOL2) LDTP11076 47.18  LDD1868 
Ataxin-2 (ATXN2) LDTP10947 10.34  LDD1868 
Ataxin-2-like protein (ATXN2L) LDTP09655 13.09  LDD1868 
Bcl-2-associated transcription factor 1 (BCLAF1) LDTP12826 13.45  LDD1868 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 11.00  LDD1868 
BRISC and BRCA1-A complex member 1 (BABAM1) LDTP12737 10.78  LDD1868 
BUB3-interacting and GLEBS motif-containing protein ZNF207 (ZNF207) LDTP00830 17.39  LDD1868 
Calponin-3 (CNN3) LDTP06383 18.25  LDD1868 
Calumenin (CALU) LDTP00887 16.56  LDD1868 
Chromatin assembly factor 1 subunit A (CHAF1A) LDTP05750 9.51  LDD1868 
Chromobox protein homolog 1 (CBX1) LDTP05189 13.27  LDD1868 
Clustered mitochondria protein homolog (CLUH) LDTP14486 35.02  LDD1868 
Coatomer subunit epsilon (COPE) LDTP00376 10.48  LDD1868 
Coronin-1B (CORO1B) LDTP11101 24.76  LDD1868 
DBIRD complex subunit ZNF326 (ZNF326) LDTP06952 17.03  LDD1868 
DDB1- and CUL4-associated factor 13 (DCAF13) LDTP12652 14.42  LDD1868 
Death domain-associated protein 6 (DAXX) LDTP13199 9.51  LDD1868 
DET1- and DDB1-associated protein 1 (DDA1) LDTP11312 11.88  LDD1868 
Diablo IAP-binding mitochondrial protein (DIABLO) LDTP12468 44.02  LDD1868 
DNA polymerase epsilon subunit 3 (POLE3) LDTP12506 10.48  LDD1868 
DnaJ homolog subfamily C member 8 (DNAJC8) LDTP01361 12.47  LDD1868 
Dynactin subunit 4 (DCTN4) LDTP13402 11.24  LDD1868 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 36.76  LDD1868 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 13.36  LDD1868 
Elongin-C (ELOC) LDTP06368 10.56  LDD1868 
Emerin (EMD) LDTP04356 20.53  LDD1868 
Endoplasmic reticulum-Golgi intermediate compartment protein 3 (ERGIC3) LDTP13828 18.25  LDD1868 
Epidermal growth factor receptor substrate 15 (EPS15) LDTP03982 9.85  LDD1868 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 14.72  LDD1868 
Eukaryotic translation initiation factor 2 subunit 2 (EIF2S2) LDTP03027 13.00  LDD1868 
Eukaryotic translation initiation factor 3 subunit H (EIF3H) LDTP00620 13.64  LDD1868 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 11.47  LDD1868 
Eukaryotic translation initiation factor 3 subunit J (EIF3J) LDTP01320 17.27  LDD1868 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 13.09  LDD1868 
Eukaryotic translation initiation factor 4H (EIF4H) LDTP06301 15.78  LDD1868 
Eukaryotic translation initiation factor 5 (EIF5) LDTP04652 15.14  LDD1868 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 11.31  LDD1868 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 18.25  LDD1868 
Far upstream element-binding protein 3 (FUBP3) LDTP10408 10.85  LDD1868 
Formin-binding protein 4 (FNBP4) LDTP15413 9.99  LDD1868 
G-rich sequence factor 1 (GRSF1) LDTP05668 10.13  LDD1868 
Ganglioside-induced differentiation-associated protein 1 (GDAP1) LDTP09324 15.56  LDD1868 
Golgi apparatus protein 1 (GLG1) LDTP09920 14.42  LDD1868 
Golgi integral membrane protein 4 (GOLIM4) LDTP00281 45.25  LDD1868 
HAUS augmin-like complex subunit 3 (HAUS3) LDTP07318 22.32  LDD1868 
HCLS1-associated protein X-1 (HAX1) LDTP00199 12.30  LDD1868 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 9.92  LDD1868 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 9.51  LDD1868 
Heterogeneous nuclear ribonucleoprotein A0 (HNRNPA0) LDTP05768 24.59  LDD1868 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 16.45  LDD1868 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 10.27  LDD1868 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 11.88  LDD1868 
Heterogeneous nuclear ribonucleoprotein H2 (HNRNPH2) LDTP04714 10.78  LDD1868 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 16.56  LDD1868 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 9.71  LDD1868 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 11.88  LDD1868 
Heterogeneous nuclear ribonucleoprotein U-like protein 1 (HNRNPUL1) LDTP11238 13.55  LDD1868 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 11.63  LDD1868 
Inhibitor of nuclear factor kappa-B kinase-interacting protein (IKBIP) LDTP07891 28.05  LDD1868 
Jupiter microtubule associated homolog 2 (JPT2) LDTP12077 29.86  LDD1868 
Keratin, type I cytoskeletal 18 (KRT18) LDTP02124 12.21  LDD1868 
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (KHDRBS1) LDTP05525 10.70  LDD1868 
Kinesin light chain 1 (KLC1) LDTP05533 9.51  LDD1868 
Kinetochore protein Spc25 (SPC25) LDTP12192 12.47  LDD1868 
La-related protein 1 (LARP1) LDTP07605 9.58  LDD1868 
Large proline-rich protein BAG6 (BAG6) LDTP04094 12.21  LDD1868 
Large ribosomal subunit protein bL27m (MRPL27) LDTP16162 15.78  LDD1868 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 9.78  LDD1868 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 14.62  LDD1868 
Large ribosomal subunit protein eL29 (RPL29) LDTP04140 10.85  LDD1868 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 23.43  LDD1868 
Large ribosomal subunit protein eL43 (RPL37A) LDTP04926 29.04  LDD1868 
Large ribosomal subunit protein uL24 (RPL26) LDTP04914 14.32  LDD1868 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 20.25  LDD1868 
Malectin (MLEC) LDTP06066 29.65  LDD1868 
Melanoma-associated antigen D2 (MAGED2) LDTP13657 11.00  LDD1868 
MICOS complex subunit MIC19 (CHCHD3) LDTP12764 11.47  LDD1868 
Microtubule-associated protein 4 (MAP4) LDTP03404 12.73  LDD1868 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 22.94  LDD1868 
Mitochondrial import receptor subunit TOM5 homolog (TOMM5) LDTP15420 36.76  LDD1868 
Myomegalin (PDE4DIP) LDTP07221 23.59  LDD1868 
Neuferricin (CYB5D2) LDTP15623 11.79  LDD1868 
Neurofilament medium polypeptide (NEFM) LDTP02181 13.09  LDD1868 
NHL repeat-containing protein 2 (NHLRC2) LDTP09049 9.71  LDD1868 
Nuclear migration protein nudC (NUDC) LDTP13817 17.03  LDD1868 
Nuclear speckle splicing regulatory protein 1 (NSRP1) LDTP11709 10.63  LDD1868 
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (NUCKS1) LDTP11764 11.16  LDD1868 
Nucleobindin-1 (NUCB1) LDTP05375 21.11  LDD1868 
Nucleobindin-2 (NUCB2) LDTP05160 47.50  LDD1868 
Nucleolar protein 14 (NOP14) LDTP05087 9.85  LDD1868 
Nucleolysin TIAR (TIAL1) LDTP05274 10.85  LDD1868 
Nucleophosmin (NPM1) LDTP02164 12.30  LDD1868 
p53 and DNA damage-regulated protein 1 (PDRG1) LDTP16099 81.01  LDD1868 
PDZ domain-containing protein GIPC1 (GIPC1) LDTP00472 14.83  LDD1868 
PHD finger protein 6 (PHF6) LDTP08552 16.80  LDD1868 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 25.28  LDD1868 
PRELI domain-containing protein 1, mitochondrial (PRELID1) LDTP13807 18.25  LDD1868 
Programmed cell death protein 5 (PDCD5) LDTP00417 23.10  LDD1868 
Proline-rich protein PRCC (PRCC) LDTP09850 20.39  LDD1868 
Protein CEBPZOS (CEBPZOS) LDTP18883 9.99  LDD1868 
Protein CMSS1 (CMSS1) LDTP18287 9.99  LDD1868 
Protein CutA (CUTA) LDTP01075 20.11  LDD1868 
Protein enabled homolog (ENAH) LDTP08984 10.85  LDD1868 
Protein FAM114A2 (FAM114A2) LDTP16080 10.93  LDD1868 
Protein FAM162A (FAM162A) LDTP10056 12.13  LDD1868 
Protein FAM98B (FAM98B) LDTP06879 16.34  LDD1868 
Protein LYRIC (MTDH) LDTP08224 14.83  LDD1868 
Protein Njmu-R1 (C17orf75) LDTP16028 16.45  LDD1868 
Protein PALS2 (PALS2) LDTP16156 10.27  LDD1868 
Protein PRRC2C (PRRC2C) LDTP14085 11.00  LDD1868 
Protein SET (SET) LDTP05277 16.68  LDD1868 
Protein TFG (TFG) LDTP09851 11.31  LDD1868 
Protein transport protein Sec16A (SEC16A) LDTP00512 11.16  LDD1868 
Protein transport protein Sec23B (SEC23B) LDTP06391 13.36  LDD1868 
Protein unc-119 homolog B (UNC119B) LDTP00105 21.26  LDD1868 
Pumilio homolog 1 (PUM1) LDTP06174 14.22  LDD1868 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 14.22  LDD1868 
RAD50-interacting protein 1 (RINT1) LDTP07476 17.88  LDD1868 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 12.64  LDD1868 
Replication protein A 32 kDa subunit (RPA2) LDTP02816 26.91  LDD1868 
Reticulocalbin-2 (RCN2) LDTP06097 15.45  LDD1868 
Reticulon-3 (RTN3) LDTP01522 49.18  LDD1868 
RNA binding motif protein, X-linked-like-1 (RBMXL1) LDTP18146 10.93  LDD1868 
RNA-binding protein 10 (RBM10) LDTP05224 14.32  LDD1868 
RNA-binding protein 12 (RBM12) LDTP16096 9.99  LDD1868 
RNA-binding protein 14 (RBM14) LDTP10684 22.32  LDD1868 
RNA-binding protein 3 (RBM3) LDTP05226 13.00  LDD1868 
RNA-binding protein 4 (RBM4) LDTP11324 11.16  LDD1868 
RNA-binding protein FUS (FUS) LDTP03775 14.42  LDD1868 
RNA-binding protein Raly (RALY) LDTP13467 11.47  LDD1868 
Serine/arginine-rich splicing factor 7 (SRSF7) LDTP06583 9.71  LDD1868 
Small ribosomal subunit protein bS16m (MRPS16) LDTP13981 21.56  LDD1868 
Small ribosomal subunit protein mS33 (MRPS33) LDTP18561 11.31  LDD1868 
Small ribosomal subunit protein uS12 (RPS23) LDTP04971 10.27  LDD1868 
Small ribosomal subunit protein uS9m (MRPS9) LDTP14792 49.52  LDD1868 
Small ubiquitin-related modifier 2 (SUMO2) LDTP04945 12.73  LDD1868 
Sorcin (SRI) LDTP03554 13.09  LDD1868 
Spartin (SPART) LDTP08735 16.00  LDD1868 
Src substrate cortactin (CTTN) LDTP06094 15.03  LDD1868 
Superkiller complex protein 3 (SKIC3) LDTP07574 14.03  LDD1868 
Survival motor neuron protein (SMN1; SMN2) LDTP06587 15.45  LDD1868 
Syntaxin-18 (STX18) LDTP13086 34.54  LDD1868 
T-complex protein 1 subunit eta (CCT7) LDTP10990 11.79  LDD1868 
TBC1 domain family member 9B (TBC1D9B) LDTP15057 9.58  LDD1868 
Testis-expressed protein 264 (TEX264) LDTP14259 12.55  LDD1868 
Tetratricopeptide repeat protein 19, mitochondrial (TTC19) LDTP07368 28.25  LDD1868 
THUMP domain-containing protein 1 (THUMPD1) LDTP12780 28.05  LDD1868 
Thyroid hormone receptor-associated protein 3 (THRAP3) LDTP13919 13.00  LDD1868 
Transforming acidic coiled-coil-containing protein 3 (TACC3) LDTP14228 11.79  LDD1868 
Translation initiation factor eIF2B subunit epsilon (EIF2B5) LDTP05765 10.20  LDD1868 
Translation initiation factor eIF2B subunit gamma (EIF2B3) LDTP12476 16.56  LDD1868 
Treacle protein (TCOF1) LDTP05867 12.55  LDD1868 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 12.21  LDD1868 
Tumor protein D54 (TPD52L2) LDTP00759 28.84  LDD1868 
U1 small nuclear ribonucleoprotein 70 kDa (SNRNP70) LDTP02292 10.06  LDD1868 
U1 small nuclear ribonucleoprotein C (SNRPC) LDTP02335 17.88  LDD1868 
Ubiquinol-cytochrome c reductase complex assembly factor 6 (UQCC6) LDTP15067 19.70  LDD1868 
Ubiquitin-associated protein 2 (UBAP2) LDTP07132 11.00  LDD1868 
Ubiquitin-associated protein 2-like (UBAP2L) LDTP06060 11.16  LDD1868 
UPF0488 protein C8orf33 (C8orf33) LDTP12025 58.08  LDD1868 
UV excision repair protein RAD23 homolog B (RAD23B) LDTP04627 10.85  LDD1868 
Vesicle transport protein SEC20 (BNIP1) LDTP05715 10.27  LDD1868 
Vesicle-trafficking protein SEC22b (SEC22B) LDTP01206 16.00  LDD1868 
Vimentin (VIM) LDTP02297 12.30  LDD1868 
YTH domain-containing family protein 1 (YTHDF1) LDTP11466 9.99  LDD1868 
YTH domain-containing family protein 3 (YTHDF3) LDTP08136 18.00  LDD1868 
Zinc finger CCCH domain-containing protein 18 (ZC3H18) LDTP08292 25.11  LDD1868 
Zinc finger RNA-binding protein (ZFR) LDTP15762 12.30  LDD1868 
------------------------------------------------------------------------------------
⏷ Show the Full List of 174 Other

Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1868 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587