Details of the Target

General Information of Target

Target ID LDTP16028
Target Name Protein Njmu-R1 (C17orf75)
Gene Name C17orf75
Gene ID 64149
Synonyms
Protein Njmu-R1
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MALPGARARGWAAAARAAQRRRRVENAGGSPSPEPAGRRAALYVHWPYCEKRCSYCNFNK
YIPRRLEEAAMQKCLVTEAQTLLRLSGVQRVESVFFGGGTPSLASPHTVAAVLEAVAQAA
HLPADLEVTLEANPTSAPGSRLAEFGAAGVNRLSIGLQSLDDTELRLLGRTHSACDALRT
LAEARRLFPGRVSVDLMLGLPAQQVGPWLGQLQELLHHCDDHLSLYQLSLERGTALFAQV
QRGALPAPDPELAAEMYQRGRAVLREAGFHQYEVSNFARNGALSTHNWTYWQCGQYLGVG
PGAHGRFMPQGAGGHTREARIQTLEPDNWMKEVMLFGHGTRKRVPLGRLELLEEVLALGL
RTDVGITHQHWQQFEPQLTLWDVFGANKEVQELLERGLLQLDHRGLRCSWEGLAVLDSLL
LTLLPQLQEAWQQRTPSPVPGG
Target Bioclass
Other
Subcellular location
Golgi apparatus, trans-Golgi network
Function As component of the WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1. May have a role in spermatogenesis.
Uniprot ID
Q9HAS0
Ensemble ID
ENST00000577809.6
HGNC ID
HGNC:30173

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 13 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
BTD
 Probe Info  		C182(0.76)  LDD2091  [2]
NAIA_5
 Probe Info  		C182(20.00)  LDD2227  [3]
AHL-Pu-1
 Probe Info  		C280(2.52)  LDD0168  [4]
DBIA
 Probe Info  		C182(25.60); C182(18.80)  LDD0209  [5]
4-Iodoacetamidophenylacetylene
 Probe Info  		C296(0.00); C357(0.00); C182(0.00); C204(0.00)  LDD0038  [6]
IA-alkyne
 Probe Info  		C296(0.00); C357(0.00); C182(0.00); C204(0.00)  LDD0036  [6]
Lodoacetamide azide
 Probe Info  		C296(0.00); C265(0.00); C153(0.00); C357(0.00)  LDD0037  [6]
WYneN
 Probe Info  		N.A.  LDD0021  [7]
WYneO
 Probe Info  		N.A.  LDD0022  [7]
IPM
 Probe Info  		N.A.  LDD0005  [7]
TFBX
 Probe Info  		C357(0.00); C182(0.00)  LDD0148  [8]
AOyne
 Probe Info  		15.00  LDD0443  [9]
PAL-AfBPP Probe
Click To Hide/Show 2 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C191
 Probe Info  		16.45  LDD1868  [10]
Alk-rapa
 Probe Info  		5.50  LDD0213  [11]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C182(1.00)  LDD2117  [2]
 LDCM0025  4SU-RNA HEK-293T C280(2.52)  LDD0168  [4]
 LDCM0026  4SU-RNA+native RNA HEK-293T C280(5.04); C182(3.47)  LDD0169  [4]
 LDCM0214  AC1 HCT 116 C182(1.10); C153(0.95); C204(1.14); C280(0.86)  LDD0531  [12]
 LDCM0215  AC10 HCT 116 C182(1.31); C153(0.81); C280(0.96); C288(0.90)  LDD0532  [12]
 LDCM0216  AC100 HCT 116 C182(1.09); C153(1.20); C280(0.87); C288(0.83)  LDD0533  [12]
 LDCM0217  AC101 HCT 116 C182(1.23); C153(1.18); C280(0.72); C288(0.83)  LDD0534  [12]
 LDCM0218  AC102 HCT 116 C182(1.22); C153(1.13); C280(0.66); C288(0.71)  LDD0535  [12]
 LDCM0219  AC103 HCT 116 C182(1.66); C153(1.31); C280(0.65); C288(0.78)  LDD0536  [12]
 LDCM0220  AC104 HCT 116 C182(0.92); C153(1.15); C280(0.70); C288(0.76)  LDD0537  [12]
 LDCM0221  AC105 HCT 116 C182(1.95); C153(1.20); C280(0.68); C288(0.78)  LDD0538  [12]
 LDCM0222  AC106 HCT 116 C182(1.59); C153(1.27); C280(0.76); C288(0.81)  LDD0539  [12]
 LDCM0223  AC107 HCT 116 C182(0.81); C153(1.19); C280(0.62); C288(0.79)  LDD0540  [12]
 LDCM0224  AC108 HCT 116 C182(2.03); C153(1.40); C280(0.92); C288(0.89)  LDD0541  [12]
 LDCM0225  AC109 HCT 116 C182(1.69); C153(1.05); C280(1.51); C288(0.81)  LDD0542  [12]
 LDCM0226  AC11 HCT 116 C182(1.49); C153(0.89); C280(0.90); C288(0.89)  LDD0543  [12]
 LDCM0227  AC110 HCT 116 C182(2.21); C153(1.16); C280(1.05); C288(0.84)  LDD0544  [12]
 LDCM0228  AC111 HCT 116 C182(1.60); C153(1.24); C280(0.94); C288(0.74)  LDD0545  [12]
 LDCM0229  AC112 HCT 116 C182(1.03); C153(1.19); C280(0.78); C288(0.81)  LDD0546  [12]
 LDCM0230  AC113 HCT 116 C182(0.80); C204(1.59); C280(1.01); C288(1.01)  LDD0547  [12]
 LDCM0231  AC114 HCT 116 C182(0.92); C204(1.58); C280(0.94); C288(1.15)  LDD0548  [12]
 LDCM0232  AC115 HCT 116 C182(0.95); C204(1.05); C280(0.93); C288(1.14)  LDD0549  [12]
 LDCM0233  AC116 HCT 116 C182(1.21); C204(1.40); C280(1.09); C288(1.20)  LDD0550  [12]
 LDCM0234  AC117 HCT 116 C182(0.95); C204(1.23); C280(0.91); C288(1.01)  LDD0551  [12]
 LDCM0235  AC118 HCT 116 C182(0.86); C204(1.28); C280(0.96); C288(0.99)  LDD0552  [12]
 LDCM0236  AC119 HCT 116 C182(1.08); C204(1.29); C280(0.99); C288(1.08)  LDD0553  [12]
 LDCM0237  AC12 HCT 116 C182(1.02); C153(0.99); C280(1.02); C288(0.97)  LDD0554  [12]
 LDCM0238  AC120 HCT 116 C182(1.07); C204(1.37); C280(0.95); C288(1.07)  LDD0555  [12]
 LDCM0239  AC121 HCT 116 C182(0.90); C204(1.41); C280(1.06); C288(1.09)  LDD0556  [12]
 LDCM0240  AC122 HCT 116 C182(0.96); C204(1.07); C280(0.97); C288(0.95)  LDD0557  [12]
 LDCM0241  AC123 HCT 116 C182(0.87); C204(1.56); C280(1.02); C288(1.06)  LDD0558  [12]
 LDCM0242  AC124 HCT 116 C182(1.01); C204(2.03); C280(1.15); C288(1.23)  LDD0559  [12]
 LDCM0243  AC125 HCT 116 C182(0.89); C204(1.40); C280(1.08); C288(1.03)  LDD0560  [12]
 LDCM0244  AC126 HCT 116 C182(1.07); C204(1.30); C280(1.09); C288(1.13)  LDD0561  [12]
 LDCM0245  AC127 HCT 116 C182(1.01); C204(1.05); C280(1.08); C288(1.06)  LDD0562  [12]
 LDCM0246  AC128 HCT 116 C182(0.76); C124(1.07); C127(1.07); C153(1.33)  LDD0563  [12]
 LDCM0247  AC129 HCT 116 C182(0.87); C124(0.93); C127(0.93); C153(1.48)  LDD0564  [12]
 LDCM0249  AC130 HCT 116 C182(1.04); C124(1.06); C127(1.06); C153(1.32)  LDD0566  [12]
 LDCM0250  AC131 HCT 116 C182(0.74); C124(1.06); C127(1.06); C153(1.28)  LDD0567  [12]
 LDCM0251  AC132 HCT 116 C182(1.45); C124(0.96); C127(0.96); C153(1.47)  LDD0568  [12]
 LDCM0252  AC133 HCT 116 C182(1.01); C124(0.90); C127(0.90); C153(1.29)  LDD0569  [12]
 LDCM0253  AC134 HCT 116 C182(1.02); C124(1.00); C127(1.00); C153(1.45)  LDD0570  [12]
 LDCM0254  AC135 HCT 116 C182(1.02); C124(1.13); C127(1.13); C153(1.28)  LDD0571  [12]
 LDCM0255  AC136 HCT 116 C182(1.03); C124(0.96); C127(0.96); C153(1.05)  LDD0572  [12]
 LDCM0256  AC137 HCT 116 C182(0.83); C124(1.08); C127(1.08); C153(1.63)  LDD0573  [12]
 LDCM0257  AC138 HCT 116 C182(1.25); C124(1.08); C127(1.08); C153(1.37)  LDD0574  [12]
 LDCM0258  AC139 HCT 116 C182(1.36); C124(1.06); C127(1.06); C153(1.78)  LDD0575  [12]
 LDCM0259  AC14 HCT 116 C182(0.94); C153(0.88); C280(0.88); C288(0.89)  LDD0576  [12]
 LDCM0260  AC140 HCT 116 C182(1.76); C124(1.05); C127(1.05); C153(1.61)  LDD0577  [12]
 LDCM0261  AC141 HCT 116 C182(1.19); C124(1.08); C127(1.08); C153(1.63)  LDD0578  [12]
 LDCM0262  AC142 HCT 116 C182(1.00); C124(1.00); C127(1.00); C153(1.38)  LDD0579  [12]
 LDCM0263  AC143 HCT 116 C182(1.42); C124(0.98); C127(0.98); C280(1.01)  LDD0580  [12]
 LDCM0264  AC144 HCT 116 C296(0.71); C182(0.78); C280(0.79); C124(0.83)  LDD0581  [12]
 LDCM0265  AC145 HCT 116 C296(0.67); C182(0.86); C280(0.94); C357(0.96)  LDD0582  [12]
 LDCM0266  AC146 HCT 116 C296(0.74); C357(0.74); C280(0.81); C182(0.83)  LDD0583  [12]
 LDCM0267  AC147 HCT 116 C296(0.72); C182(0.80); C124(1.15); C127(1.15)  LDD0584  [12]
 LDCM0268  AC148 HCT 116 C357(0.58); C182(0.74); C296(0.89); C124(1.04)  LDD0585  [12]
 LDCM0269  AC149 HCT 116 C357(0.68); C296(0.71); C280(0.83); C182(0.85)  LDD0586  [12]
 LDCM0270  AC15 HCT 116 C296(0.79); C288(0.81); C280(0.82); C153(0.91)  LDD0587  [12]
 LDCM0271  AC150 HCT 116 C296(0.73); C357(0.77); C182(0.87); C124(0.89)  LDD0588  [12]
 LDCM0272  AC151 HCT 116 C124(0.61); C127(0.61); C296(0.76); C280(0.84)  LDD0589  [12]
 LDCM0273  AC152 HCT 116 C357(0.73); C182(0.73); C296(0.80); C124(0.91)  LDD0590  [12]
 LDCM0274  AC153 HCT 116 C357(0.29); C296(0.94); C182(0.95); C124(1.03)  LDD0591  [12]
 LDCM0621  AC154 HCT 116 C182(0.81); C124(1.04); C127(1.04); C280(0.90)  LDD2158  [12]
 LDCM0622  AC155 HCT 116 C182(0.81); C124(0.73); C127(0.73); C280(0.87)  LDD2159  [12]
 LDCM0623  AC156 HCT 116 C182(0.82); C124(1.03); C127(1.03); C280(0.84)  LDD2160  [12]
 LDCM0624  AC157 HCT 116 C182(0.89); C124(0.92); C127(0.92); C280(0.98)  LDD2161  [12]
 LDCM0276  AC17 HCT 116 C204(0.76); C153(0.81); C288(0.88); C296(0.88)  LDD0593  [12]
 LDCM0277  AC18 HCT 116 C296(0.93); C153(0.94); C280(0.96); C288(1.01)  LDD0594  [12]
 LDCM0278  AC19 HCT 116 C153(0.81); C204(0.84); C280(0.88); C288(0.90)  LDD0595  [12]
 LDCM0279  AC2 HCT 116 C296(0.83); C280(0.91); C288(0.95); C153(1.12)  LDD0596  [12]
 LDCM0280  AC20 HCT 116 C204(0.88); C280(0.90); C153(0.91); C288(0.92)  LDD0597  [12]
 LDCM0281  AC21 HCT 116 C296(0.80); C153(0.83); C204(0.87); C280(0.94)  LDD0598  [12]
 LDCM0282  AC22 HCT 116 C204(0.83); C153(0.87); C280(0.89); C296(0.90)  LDD0599  [12]
 LDCM0283  AC23 HCT 116 C153(0.79); C296(0.83); C204(0.85); C288(0.98)  LDD0600  [12]
 LDCM0284  AC24 HCT 116 C204(0.72); C153(0.89); C296(0.90); C288(0.99)  LDD0601  [12]
 LDCM0285  AC25 HCT 116 C280(0.87); C204(0.91); C288(0.94); C357(0.99)  LDD0602  [12]
 LDCM0286  AC26 HCT 116 C280(0.80); C204(0.91); C288(0.94); C357(0.96)  LDD0603  [12]
 LDCM0287  AC27 HCT 116 C280(0.73); C357(0.88); C288(0.92); C296(0.95)  LDD0604  [12]
 LDCM0288  AC28 HCT 116 C204(0.85); C280(0.89); C357(0.93); C288(0.98)  LDD0605  [12]
 LDCM0289  AC29 HCT 116 C357(0.83); C280(0.88); C288(0.98); C296(1.00)  LDD0606  [12]
 LDCM0290  AC3 HCT 116 C296(0.84); C288(0.88); C280(0.88); C153(1.14)  LDD0607  [12]
 LDCM0291  AC30 HCT 116 C280(0.81); C357(0.87); C288(0.89); C296(0.99)  LDD0608  [12]
 LDCM0292  AC31 HCT 116 C280(0.78); C288(0.87); C296(1.03); C204(1.06)  LDD0609  [12]
 LDCM0293  AC32 HCT 116 C280(0.87); C357(0.89); C288(0.98); C296(1.06)  LDD0610  [12]
 LDCM0294  AC33 HCT 116 C280(0.73); C357(0.80); C288(0.90); C296(0.96)  LDD0611  [12]
 LDCM0295  AC34 HCT 116 C357(0.75); C280(0.83); C296(0.87); C288(0.97)  LDD0612  [12]
 LDCM0296  AC35 HCT 116 C182(0.90); C288(0.96); C280(1.08); C153(1.20)  LDD0613  [12]
 LDCM0297  AC36 HCT 116 C204(0.68); C153(0.88); C288(1.01); C280(1.04)  LDD0614  [12]
 LDCM0298  AC37 HCT 116 C204(0.80); C153(0.84); C288(0.89); C296(0.95)  LDD0615  [12]
 LDCM0299  AC38 HCT 116 C280(0.89); C288(0.93); C153(0.97); C182(0.98)  LDD0616  [12]
 LDCM0300  AC39 HCT 116 C296(0.91); C153(0.98); C280(0.99); C288(1.01)  LDD0617  [12]
 LDCM0301  AC4 HCT 116 C296(0.79); C288(0.82); C280(0.84); C204(1.17)  LDD0618  [12]
 LDCM0302  AC40 HCT 116 C153(0.79); C204(0.84); C280(0.97); C288(0.98)  LDD0619  [12]
 LDCM0303  AC41 HCT 116 C153(0.72); C296(0.90); C280(1.04); C288(1.04)  LDD0620  [12]
 LDCM0304  AC42 HCT 116 C153(0.84); C296(0.91); C280(0.96); C182(1.00)  LDD0621  [12]
 LDCM0305  AC43 HCT 116 C153(0.88); C296(0.97); C280(1.00); C288(1.07)  LDD0622  [12]
 LDCM0306  AC44 HCT 116 C153(0.69); C296(1.01); C280(1.01); C288(1.01)  LDD0623  [12]
 LDCM0307  AC45 HCT 116 C153(0.75); C204(0.95); C296(1.00); C288(1.02)  LDD0624  [12]
 LDCM0308  AC46 HCT 116 C204(0.89); C153(0.90); C357(1.01); C182(1.02)  LDD0625  [12]
 LDCM0309  AC47 HCT 116 C153(0.77); C182(0.84); C357(1.08); C288(1.09)  LDD0626  [12]
 LDCM0310  AC48 HCT 116 C153(0.84); C182(0.86); C204(1.05); C288(1.08)  LDD0627  [12]
 LDCM0311  AC49 HCT 116 C182(0.97); C153(0.98); C204(1.02); C357(1.15)  LDD0628  [12]
 LDCM0312  AC5 HCT 116 C296(0.76); C288(0.86); C280(0.89); C204(1.15)  LDD0629  [12]
 LDCM0313  AC50 HCT 116 C182(0.92); C357(0.97); C153(0.99); C204(1.06)  LDD0630  [12]
 LDCM0314  AC51 HCT 116 C204(0.84); C153(0.89); C182(0.99); C357(1.10)  LDD0631  [12]
 LDCM0315  AC52 HCT 116 C182(0.76); C204(0.78); C153(0.83); C288(1.05)  LDD0632  [12]
 LDCM0316  AC53 HCT 116 C153(0.59); C357(0.83); C204(0.96); C182(1.00)  LDD0633  [12]
 LDCM0317  AC54 HCT 116 C357(0.78); C153(0.82); C182(0.96); C288(1.11)  LDD0634  [12]
 LDCM0318  AC55 HCT 116 C153(0.68); C357(0.89); C182(0.97); C204(1.01)  LDD0635  [12]
 LDCM0319  AC56 HCT 116 C153(0.59); C357(0.93); C182(0.98); C204(1.07)  LDD0636  [12]
 LDCM0320  AC57 HCT 116 C280(0.84); C153(0.90); C288(0.93); C182(0.98)  LDD0637  [12]
 LDCM0321  AC58 HCT 116 C280(0.86); C153(0.88); C288(0.92); C182(1.20)  LDD0638  [12]
 LDCM0322  AC59 HCT 116 C280(0.85); C153(0.89); C288(0.98); C182(1.20)  LDD0639  [12]
 LDCM0323  AC6 HCT 116 C296(0.77); C153(0.82); C288(0.83); C280(0.84)  LDD0640  [12]
 LDCM0324  AC60 HCT 116 C280(0.74); C153(0.75); C288(0.92); C182(1.09)  LDD0641  [12]
 LDCM0325  AC61 HCT 116 C153(0.81); C280(0.86); C288(0.91); C182(2.01)  LDD0642  [12]
 LDCM0326  AC62 HCT 116 C153(0.78); C280(0.89); C288(1.00); C182(1.27)  LDD0643  [12]
 LDCM0327  AC63 HCT 116 C153(0.74); C280(0.86); C288(0.98); C182(1.15)  LDD0644  [12]
 LDCM0328  AC64 HCT 116 C153(0.84); C280(0.85); C288(0.93); C182(1.07)  LDD0645  [12]
 LDCM0329  AC65 HCT 116 C153(0.89); C280(0.96); C288(1.11); C182(1.47)  LDD0646  [12]
 LDCM0330  AC66 HCT 116 C153(0.89); C280(0.93); C288(1.08); C182(1.55)  LDD0647  [12]
 LDCM0331  AC67 HCT 116 C153(0.85); C280(0.92); C288(1.07); C182(1.43)  LDD0648  [12]
 LDCM0332  AC68 HCT 116 C153(0.90); C288(0.91); C280(0.93); C204(0.96)  LDD0649  [12]
 LDCM0333  AC69 HCT 116 C153(0.90); C288(0.90); C280(0.91); C182(0.92)  LDD0650  [12]
 LDCM0334  AC7 HCT 116 C296(0.78); C153(0.84); C288(0.84); C280(0.87)  LDD0651  [12]
 LDCM0335  AC70 HCT 116 C280(0.91); C288(0.93); C153(1.01); C204(1.07)  LDD0652  [12]
 LDCM0336  AC71 HCT 116 C280(0.93); C182(0.93); C288(0.94); C153(1.21)  LDD0653  [12]
 LDCM0337  AC72 HCT 116 C182(0.85); C288(0.94); C204(0.95); C280(0.95)  LDD0654  [12]
 LDCM0338  AC73 HCT 116 C288(1.06); C280(1.06); C153(1.07); C204(1.53)  LDD0655  [12]
 LDCM0339  AC74 HCT 116 C288(1.09); C280(1.10); C204(1.24); C153(1.25)  LDD0656  [12]
 LDCM0340  AC75 HCT 116 C153(0.99); C280(1.18); C204(1.24); C288(1.26)  LDD0657  [12]
 LDCM0341  AC76 HCT 116 C288(1.04); C280(1.12); C204(1.16); C182(1.20)  LDD0658  [12]
 LDCM0342  AC77 HCT 116 C153(0.92); C204(0.93); C280(1.01); C288(1.03)  LDD0659  [12]
 LDCM0343  AC78 HCT 116 C288(0.93); C280(0.93); C182(0.94); C153(0.95)  LDD0660  [12]
 LDCM0344  AC79 HCT 116 C182(0.79); C280(0.90); C288(1.05); C204(1.17)  LDD0661  [12]
 LDCM0345  AC8 HCT 116 C296(0.80); C153(0.87); C280(0.93); C288(0.94)  LDD0662  [12]
 LDCM0346  AC80 HCT 116 C153(1.00); C288(1.02); C182(1.02); C204(1.08)  LDD0663  [12]
 LDCM0347  AC81 HCT 116 C204(0.45); C288(0.89); C182(0.93); C280(0.98)  LDD0664  [12]
 LDCM0348  AC82 HCT 116 C182(1.10); C153(1.20); C288(1.22); C280(1.27)  LDD0665  [12]
 LDCM0349  AC83 HCT 116 C124(0.29); C127(0.29); C153(0.89); C280(0.92)  LDD0666  [12]
 LDCM0350  AC84 HCT 116 C124(0.37); C127(0.37); C153(0.91); C280(1.00)  LDD0667  [12]
 LDCM0351  AC85 HCT 116 C124(0.25); C127(0.25); C153(0.86); C280(0.93)  LDD0668  [12]
 LDCM0352  AC86 HCT 116 C124(0.34); C127(0.34); C280(0.92); C153(0.94)  LDD0669  [12]
 LDCM0353  AC87 HCT 116 C124(0.37); C127(0.37); C280(0.96); C153(1.00)  LDD0670  [12]
 LDCM0354  AC88 HCT 116 C124(0.32); C127(0.32); C280(0.98); C288(0.99)  LDD0671  [12]
 LDCM0355  AC89 HCT 116 C124(0.28); C127(0.28); C280(1.04); C288(1.09)  LDD0672  [12]
 LDCM0357  AC90 HCT 116 C124(0.28); C127(0.28); C153(0.92); C182(1.05)  LDD0674  [12]
 LDCM0358  AC91 HCT 116 C124(0.39); C127(0.39); C153(0.97); C280(1.08)  LDD0675  [12]
 LDCM0359  AC92 HCT 116 C124(0.27); C127(0.27); C153(0.85); C280(0.97)  LDD0676  [12]
 LDCM0360  AC93 HCT 116 C124(0.33); C127(0.33); C182(0.87); C153(0.96)  LDD0677  [12]
 LDCM0361  AC94 HCT 116 C124(0.41); C127(0.41); C182(0.91); C153(0.95)  LDD0678  [12]
 LDCM0362  AC95 HCT 116 C124(0.36); C127(0.36); C280(0.85); C288(0.91)  LDD0679  [12]
 LDCM0363  AC96 HCT 116 C124(0.56); C127(0.56); C153(0.96); C288(1.04)  LDD0680  [12]
 LDCM0364  AC97 HCT 116 C124(0.30); C127(0.30); C280(1.01); C153(1.03)  LDD0681  [12]
 LDCM0365  AC98 HCT 116 C296(0.56); C280(0.74); C288(0.96); C153(1.24)  LDD0682  [12]
 LDCM0366  AC99 HCT 116 C296(0.56); C280(0.79); C288(0.81); C182(0.97)  LDD0683  [12]
 LDCM0545  Acetamide MDA-MB-231 C182(0.59)  LDD2138  [2]
 LDCM0248  AKOS034007472 HCT 116 C182(1.34); C153(0.99); C280(0.99); C288(0.94)  LDD0565  [12]
 LDCM0356  AKOS034007680 HCT 116 C296(0.75); C153(0.85); C288(0.87); C280(0.88)  LDD0673  [12]
 LDCM0275  AKOS034007705 HCT 116 C296(0.78); C280(0.90); C288(0.91); C153(1.02)  LDD0592  [12]
 LDCM0156  Aniline NCI-H1299 11.74  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C288(1.22); C182(1.37)  LDD2171  [12]
 LDCM0498  BS-3668 MDA-MB-231 C182(0.76)  LDD2091  [2]
 LDCM0632  CL-Sc Hep-G2 C182(20.00)  LDD2227  [3]
 LDCM0367  CL1 HCT 116 C204(0.77); C182(0.88); C288(0.98); C296(1.00)  LDD0684  [12]
 LDCM0368  CL10 HCT 116 C204(0.63); C296(0.76); C182(0.92); C280(1.04)  LDD0685  [12]
 LDCM0369  CL100 HCT 116 C296(0.83); C288(0.88); C280(0.89); C153(1.04)  LDD0686  [12]
 LDCM0370  CL101 HCT 116 C296(0.72); C288(0.83); C280(0.84); C153(0.92)  LDD0687  [12]
 LDCM0371  CL102 HCT 116 C296(0.81); C280(0.89); C153(0.92); C288(0.94)  LDD0688  [12]
 LDCM0372  CL103 HCT 116 C296(0.77); C153(0.88); C280(0.97); C288(1.00)  LDD0689  [12]
 LDCM0373  CL104 HCT 116 C153(0.82); C280(0.83); C296(0.85); C288(0.88)  LDD0690  [12]
 LDCM0374  CL105 HCT 116 C296(0.74); C204(0.76); C288(0.82); C280(0.83)  LDD0691  [12]
 LDCM0375  CL106 HCT 116 C204(0.67); C296(0.75); C153(0.76); C280(0.90)  LDD0692  [12]
 LDCM0376  CL107 HCT 116 C296(0.82); C280(0.86); C153(0.87); C288(0.94)  LDD0693  [12]
 LDCM0377  CL108 HCT 116 C204(0.87); C296(0.89); C280(0.92); C288(1.00)  LDD0694  [12]
 LDCM0378  CL109 HCT 116 C204(0.76); C153(0.78); C296(0.78); C280(0.83)  LDD0695  [12]
 LDCM0379  CL11 HCT 116 C204(0.68); C296(0.88); C182(1.10); C288(1.13)  LDD0696  [12]
 LDCM0380  CL110 HCT 116 C296(0.68); C153(0.73); C204(0.75); C280(0.96)  LDD0697  [12]
 LDCM0381  CL111 HCT 116 C204(0.67); C296(0.76); C153(0.79); C280(0.86)  LDD0698  [12]
 LDCM0382  CL112 HCT 116 C357(0.91); C182(0.92); C280(1.01); C296(1.03)  LDD0699  [12]
 LDCM0383  CL113 HCT 116 C280(0.86); C357(0.89); C296(0.94); C288(1.00)  LDD0700  [12]
 LDCM0384  CL114 HCT 116 C357(0.74); C296(0.84); C204(0.85); C280(0.89)  LDD0701  [12]
 LDCM0385  CL115 HCT 116 C357(0.79); C280(0.83); C204(0.89); C296(0.91)  LDD0702  [12]
 LDCM0386  CL116 HCT 116 C280(0.73); C357(0.77); C288(0.88); C296(0.93)  LDD0703  [12]
 LDCM0387  CL117 HCT 116 C182(0.76); C153(0.81); C296(1.12); C204(1.13)  LDD0704  [12]
 LDCM0388  CL118 HCT 116 C296(0.97); C288(0.99); C153(1.00); C280(1.02)  LDD0705  [12]
 LDCM0389  CL119 HCT 116 C204(0.84); C296(1.00); C153(1.02); C280(1.02)  LDD0706  [12]
 LDCM0390  CL12 HCT 116 C204(0.82); C182(0.90); C296(1.03); C280(1.13)  LDD0707  [12]
 LDCM0391  CL120 HCT 116 C153(0.78); C296(0.87); C204(0.94); C280(1.04)  LDD0708  [12]
 LDCM0392  CL121 HCT 116 C204(0.37); C153(0.72); C357(0.86); C182(0.90)  LDD0709  [12]
 LDCM0393  CL122 HCT 116 C153(0.70); C204(0.90); C357(0.90); C182(0.99)  LDD0710  [12]
 LDCM0394  CL123 HCT 116 C153(0.60); C182(0.71); C357(0.88); C204(0.99)  LDD0711  [12]
 LDCM0395  CL124 HCT 116 C153(0.66); C182(0.88); C357(1.03); C204(1.16)  LDD0712  [12]
 LDCM0396  CL125 HCT 116 C153(0.87); C280(0.92); C288(1.05); C182(1.24)  LDD0713  [12]
 LDCM0397  CL126 HCT 116 C280(0.77); C153(0.88); C288(0.90); C182(1.13)  LDD0714  [12]
 LDCM0398  CL127 HCT 116 C153(0.75); C280(0.90); C288(0.96); C182(1.19)  LDD0715  [12]
 LDCM0399  CL128 HCT 116 C153(0.87); C280(0.94); C288(0.96); C182(1.18)  LDD0716  [12]
 LDCM0400  CL13 HCT 116 C182(0.78); C204(0.80); C296(0.84); C280(0.99)  LDD0717  [12]
 LDCM0401  CL14 HCT 116 C204(0.64); C296(0.80); C280(1.02); C288(1.05)  LDD0718  [12]
 LDCM0402  CL15 HCT 116 C204(0.67); C296(0.78); C182(0.91); C288(0.95)  LDD0719  [12]
 LDCM0403  CL16 HCT 116 C280(0.83); C153(0.83); C296(0.88); C288(0.89)  LDD0720  [12]
 LDCM0404  CL17 HCT 116 C296(0.68); C153(0.79); C280(0.84); C288(0.89)  LDD0721  [12]
 LDCM0405  CL18 HCT 116 C296(0.60); C153(0.80); C280(0.86); C182(0.91)  LDD0722  [12]
 LDCM0406  CL19 HCT 116 C296(0.72); C153(0.86); C280(0.91); C288(0.98)  LDD0723  [12]
 LDCM0407  CL2 HCT 116 C204(0.61); C296(0.96); C288(1.04); C280(1.10)  LDD0724  [12]
 LDCM0408  CL20 HCT 116 C296(0.82); C280(0.87); C153(0.90); C182(1.03)  LDD0725  [12]
 LDCM0409  CL21 HCT 116 C296(0.75); C153(0.94); C182(1.06); C280(1.09)  LDD0726  [12]
 LDCM0410  CL22 HCT 116 C296(0.90); C280(0.98); C182(0.99); C153(1.07)  LDD0727  [12]
 LDCM0411  CL23 HCT 116 C296(0.81); C280(0.82); C153(0.90); C288(1.08)  LDD0728  [12]
 LDCM0412  CL24 HCT 116 C296(0.80); C280(0.92); C153(0.93); C182(1.08)  LDD0729  [12]
 LDCM0413  CL25 HCT 116 C182(1.27); C153(0.88); C280(1.00); C288(0.98)  LDD0730  [12]
 LDCM0414  CL26 HCT 116 C182(0.95); C153(0.88); C280(0.92); C288(1.01)  LDD0731  [12]
 LDCM0415  CL27 HCT 116 C182(1.02); C153(0.94); C280(0.79); C288(0.84)  LDD0732  [12]
 LDCM0416  CL28 HCT 116 C182(1.13); C153(0.95); C280(0.92); C288(1.06)  LDD0733  [12]
 LDCM0417  CL29 HCT 116 C182(1.32); C153(0.94); C280(0.94); C288(1.08)  LDD0734  [12]
 LDCM0418  CL3 HCT 116 C182(1.09); C204(0.50); C280(1.12); C288(1.08)  LDD0735  [12]
 LDCM0419  CL30 HCT 116 C182(1.12); C153(0.81); C280(0.91); C288(1.06)  LDD0736  [12]
 LDCM0420  CL31 HCT 116 C182(1.05); C153(1.00); C280(0.97); C288(1.00)  LDD0737  [12]
 LDCM0421  CL32 HCT 116 C182(1.41); C153(0.92); C280(0.83); C288(1.19)  LDD0738  [12]
 LDCM0422  CL33 HCT 116 C182(1.96); C153(0.83); C280(0.76); C288(0.88)  LDD0739  [12]
 LDCM0423  CL34 HCT 116 C182(1.52); C153(1.10); C280(0.89); C288(1.02)  LDD0740  [12]
 LDCM0424  CL35 HCT 116 C182(1.45); C153(0.86); C280(0.92); C288(1.01)  LDD0741  [12]
 LDCM0425  CL36 HCT 116 C182(1.67); C153(1.02); C280(0.91); C288(1.15)  LDD0742  [12]
 LDCM0426  CL37 HCT 116 C182(1.77); C153(1.04); C280(1.01); C288(1.08)  LDD0743  [12]
 LDCM0428  CL39 HCT 116 C182(1.59); C153(0.88); C280(0.91); C288(0.95)  LDD0745  [12]
 LDCM0429  CL4 HCT 116 C182(2.00); C204(0.66); C280(1.09); C288(1.00)  LDD0746  [12]
 LDCM0430  CL40 HCT 116 C182(1.62); C153(0.85); C280(0.94); C288(1.00)  LDD0747  [12]
 LDCM0431  CL41 HCT 116 C182(1.50); C153(1.02); C280(0.88); C288(1.13)  LDD0748  [12]
 LDCM0432  CL42 HCT 116 C182(1.77); C153(0.93); C280(1.01); C288(1.25)  LDD0749  [12]
 LDCM0433  CL43 HCT 116 C182(1.64); C153(0.95); C280(1.01); C288(1.18)  LDD0750  [12]
 LDCM0434  CL44 HCT 116 C182(1.42); C153(0.98); C280(0.88); C288(1.02)  LDD0751  [12]
 LDCM0435  CL45 HCT 116 C182(1.47); C153(0.93); C280(0.98); C288(1.09)  LDD0752  [12]
 LDCM0436  CL46 HCT 116 C182(1.01); C124(0.78); C127(0.78); C153(1.01)  LDD0753  [12]
 LDCM0437  CL47 HCT 116 C182(1.10); C124(0.89); C127(0.89); C153(1.01)  LDD0754  [12]
 LDCM0438  CL48 HCT 116 C182(0.96); C124(0.73); C127(0.73); C153(1.06)  LDD0755  [12]
 LDCM0439  CL49 HCT 116 C182(1.00); C124(0.89); C127(0.89); C153(0.99)  LDD0756  [12]
 LDCM0440  CL5 HCT 116 C182(1.14); C204(0.79); C280(1.06); C288(1.07)  LDD0757  [12]
 LDCM0441  CL50 HCT 116 C182(1.26); C124(0.83); C127(0.83); C153(0.97)  LDD0758  [12]
 LDCM0442  CL51 HCT 116 C182(1.41); C124(0.88); C127(0.88); C153(1.02)  LDD0759  [12]
 LDCM0443  CL52 HCT 116 C182(1.16); C124(0.80); C127(0.80); C153(0.95)  LDD0760  [12]
 LDCM0444  CL53 HCT 116 C182(1.04); C124(1.08); C127(1.08); C153(0.93)  LDD0761  [12]
 LDCM0445  CL54 HCT 116 C182(1.03); C124(1.10); C127(1.10); C153(0.90)  LDD0762  [12]
 LDCM0446  CL55 HCT 116 C182(1.15); C124(1.13); C127(1.13); C153(1.00)  LDD0763  [12]
 LDCM0447  CL56 HCT 116 C182(0.98); C124(1.03); C127(1.03); C153(1.04)  LDD0764  [12]
 LDCM0448  CL57 HCT 116 C182(1.06); C124(0.97); C127(0.97); C153(0.93)  LDD0765  [12]
 LDCM0449  CL58 HCT 116 C182(1.01); C124(0.93); C127(0.93); C153(0.89)  LDD0766  [12]
 LDCM0450  CL59 HCT 116 C182(1.21); C124(1.27); C127(1.27); C153(0.97)  LDD0767  [12]
 LDCM0451  CL6 HCT 116 C182(1.28); C204(0.54); C280(0.91); C288(0.90)  LDD0768  [12]
 LDCM0452  CL60 HCT 116 C182(1.14); C124(0.97); C127(0.97); C153(0.92)  LDD0769  [12]
 LDCM0453  CL61 HCT 116 C182(0.70); C153(0.92); C204(0.83); C280(1.20)  LDD0770  [12]
 LDCM0454  CL62 HCT 116 C182(1.00); C153(1.04); C204(0.78); C280(0.89)  LDD0771  [12]
 LDCM0455  CL63 HCT 116 C182(0.93); C153(0.98); C204(0.83); C280(0.99)  LDD0772  [12]
 LDCM0456  CL64 HCT 116 C182(0.82); C153(0.89); C204(0.90); C280(0.93)  LDD0773  [12]
 LDCM0457  CL65 HCT 116 C182(1.11); C153(1.00); C204(0.96); C280(0.99)  LDD0774  [12]
 LDCM0458  CL66 HCT 116 C182(0.93); C153(1.23); C204(1.24); C280(0.88)  LDD0775  [12]
 LDCM0459  CL67 HCT 116 C182(0.84); C153(1.10); C204(0.79); C280(1.00)  LDD0776  [12]
 LDCM0460  CL68 HCT 116 C182(0.72); C153(0.92); C204(0.76); C280(1.09)  LDD0777  [12]
 LDCM0461  CL69 HCT 116 C182(0.82); C153(0.89); C204(0.58); C280(0.90)  LDD0778  [12]
 LDCM0462  CL7 HCT 116 C182(0.96); C204(0.69); C280(0.97); C288(1.00)  LDD0779  [12]
 LDCM0463  CL70 HCT 116 C182(0.72); C153(1.09); C204(0.77); C280(0.94)  LDD0780  [12]
 LDCM0464  CL71 HCT 116 C182(0.79); C153(1.03); C204(0.93); C280(0.97)  LDD0781  [12]
 LDCM0465  CL72 HCT 116 C182(0.71); C153(1.00); C204(0.86); C280(1.07)  LDD0782  [12]
 LDCM0466  CL73 HCT 116 C182(0.96); C153(1.03); C204(0.85); C280(0.95)  LDD0783  [12]
 LDCM0467  CL74 HCT 116 C182(0.87); C153(0.92); C204(0.71); C280(0.95)  LDD0784  [12]
 LDCM0469  CL76 HCT 116 C182(1.06); C153(1.14); C204(0.84); C280(1.06)  LDD0786  [12]
 LDCM0470  CL77 HCT 116 C182(0.68); C153(1.02); C204(0.79); C280(1.03)  LDD0787  [12]
 LDCM0471  CL78 HCT 116 C182(1.52); C153(1.21); C204(1.23); C280(1.11)  LDD0788  [12]
 LDCM0472  CL79 HCT 116 C182(1.71); C153(1.08); C204(1.10); C280(1.10)  LDD0789  [12]
 LDCM0473  CL8 HCT 116 C182(0.97); C204(0.85); C280(1.28); C288(1.23)  LDD0790  [12]
 LDCM0474  CL80 HCT 116 C182(1.47); C153(1.01); C204(0.91); C280(0.90)  LDD0791  [12]
 LDCM0475  CL81 HCT 116 C182(1.30); C153(1.29); C204(1.10); C280(1.12)  LDD0792  [12]
 LDCM0476  CL82 HCT 116 C182(1.59); C153(1.18); C204(1.55); C280(1.38)  LDD0793  [12]
 LDCM0477  CL83 HCT 116 C182(2.09); C153(1.02); C204(1.47); C280(1.14)  LDD0794  [12]
 LDCM0478  CL84 HCT 116 C182(7.44); C153(1.36); C204(1.55); C280(1.27)  LDD0795  [12]
 LDCM0479  CL85 HCT 116 C182(2.35); C153(1.12); C204(1.04); C280(1.14)  LDD0796  [12]
 LDCM0480  CL86 HCT 116 C182(1.85); C153(1.13); C204(1.17); C280(1.06)  LDD0797  [12]
 LDCM0481  CL87 HCT 116 C182(1.87); C153(1.09); C204(1.62); C280(1.17)  LDD0798  [12]
 LDCM0482  CL88 HCT 116 C182(1.77); C153(1.03); C204(1.00); C280(1.32)  LDD0799  [12]
 LDCM0483  CL89 HCT 116 C182(2.25); C153(1.43); C204(1.44); C280(1.41)  LDD0800  [12]
 LDCM0484  CL9 HCT 116 C182(0.95); C204(0.87); C280(1.04); C288(1.01)  LDD0801  [12]
 LDCM0485  CL90 HCT 116 C182(2.04); C153(0.99); C204(0.59); C280(1.25)  LDD0802  [12]
 LDCM0486  CL91 HCT 116 C182(1.31); C153(0.95); C204(1.09); C280(0.85)  LDD0803  [12]
 LDCM0487  CL92 HCT 116 C182(1.05); C153(0.95); C204(1.04); C280(0.91)  LDD0804  [12]
 LDCM0488  CL93 HCT 116 C182(1.12); C153(1.26); C204(1.02); C280(0.90)  LDD0805  [12]
 LDCM0489  CL94 HCT 116 C182(1.41); C153(1.00); C204(0.94); C280(0.84)  LDD0806  [12]
 LDCM0490  CL95 HCT 116 C182(1.34); C153(0.98); C204(0.88); C280(0.92)  LDD0807  [12]
 LDCM0491  CL96 HCT 116 C182(1.17); C153(1.17); C204(0.87); C280(0.89)  LDD0808  [12]
 LDCM0492  CL97 HCT 116 C182(1.20); C153(1.10); C204(1.06); C280(0.85)  LDD0809  [12]
 LDCM0493  CL98 HCT 116 C182(1.35); C153(0.86); C204(1.15); C280(0.85)  LDD0810  [12]
 LDCM0494  CL99 HCT 116 C182(1.28); C153(0.96); C204(1.12); C280(0.97)  LDD0811  [12]
 LDCM0634  CY-0357 Hep-G2 C182(0.78)  LDD2228  [3]
 LDCM0495  E2913 HEK-293T C39(1.23); C357(0.97); C204(0.90); C265(0.92)  LDD1698  [13]
 LDCM0213  Electrophilic fragment 2 MDA-MB-231 C182(16.84)  LDD1702  [2]
 LDCM0625  F8 Ramos C182(1.54); C357(1.26)  LDD2187  [14]
 LDCM0572  Fragment10 Ramos C182(2.56); C357(0.86)  LDD2189  [14]
 LDCM0573  Fragment11 Ramos C182(1.55); C357(0.35); C39(9.51)  LDD2190  [14]
 LDCM0574  Fragment12 Ramos C182(2.08); C357(0.83)  LDD2191  [14]
 LDCM0575  Fragment13 Ramos C182(1.10); C357(0.72)  LDD2192  [14]
 LDCM0576  Fragment14 Ramos C182(1.55); C357(0.95); C39(1.04)  LDD2193  [14]
 LDCM0579  Fragment20 Ramos C182(2.34); C357(0.97)  LDD2194  [14]
 LDCM0580  Fragment21 Ramos C182(0.89); C357(0.77)  LDD2195  [14]
 LDCM0582  Fragment23 Ramos C182(1.45); C357(0.68)  LDD2196  [14]
 LDCM0578  Fragment27 Ramos C182(0.82); C357(0.83)  LDD2197  [14]
 LDCM0586  Fragment28 Ramos C182(0.73); C357(0.62); C39(0.67)  LDD2198  [14]
 LDCM0588  Fragment30 Ramos C182(1.44); C357(1.03)  LDD2199  [14]
 LDCM0589  Fragment31 Ramos C182(1.09); C357(0.80)  LDD2200  [14]
 LDCM0590  Fragment32 Ramos C182(3.10); C357(0.75)  LDD2201  [14]
 LDCM0468  Fragment33 HCT 116 C182(0.69); C153(0.99); C204(0.87); C280(0.98)  LDD0785  [12]
 LDCM0596  Fragment38 Ramos C182(1.05); C357(0.90)  LDD2203  [14]
 LDCM0566  Fragment4 Ramos C182(1.19); C357(0.93); C39(0.65)  LDD2184  [14]
 LDCM0427  Fragment51 HCT 116 C182(1.89); C153(0.93); C280(1.07); C288(1.15)  LDD0744  [12]
 LDCM0610  Fragment52 Ramos C182(1.40); C357(1.07)  LDD2204  [14]
 LDCM0614  Fragment56 Ramos C182(1.31); C357(1.49)  LDD2205  [14]
 LDCM0569  Fragment7 Ramos C182(1.59); C357(1.21); C39(0.46)  LDD2186  [14]
 LDCM0571  Fragment9 Ramos C182(3.56); C357(1.20)  LDD2188  [14]
 LDCM0022  KB02 HEK-293T C357(0.92); C153(0.99); C296(1.05); C182(0.89)  LDD1492  [13]
 LDCM0023  KB03 Jurkat C182(25.60); C182(18.80)  LDD0209  [5]
 LDCM0024  KB05 COLO792 C182(2.45)  LDD3310  [15]
 LDCM0500  Nucleophilic fragment 13a MDA-MB-231 C182(0.99)  LDD2093  [2]
 LDCM0506  Nucleophilic fragment 16a MDA-MB-231 C182(0.89)  LDD2099  [2]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C182(0.92)  LDD2107  [2]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C182(0.99)  LDD2109  [2]
 LDCM0518  Nucleophilic fragment 22a MDA-MB-231 C182(1.26)  LDD2111  [2]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C182(0.91)  LDD2123  [2]
 LDCM0532  Nucleophilic fragment 29a MDA-MB-231 C182(0.87)  LDD2125  [2]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C182(1.09)  LDD2127  [2]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C182(0.81)  LDD2129  [2]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C182(1.39)  LDD2136  [2]
 LDCM0544  Nucleophilic fragment 39 MDA-MB-231 C182(1.11)  LDD2137  [2]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C182(0.82)  LDD2140  [2]
 LDCM0628  OTUB2-COV-1 HEK-293T C182(0.79)  LDD2207  [16]
 LDCM0131  RA190 MM1.R C288(1.33)  LDD0304  [17]
 LDCM0090  Rapamycin JHH-7 5.50  LDD0213  [11]
 LDCM0021  THZ1 HCT 116 C288(1.22); C182(1.37)  LDD2173  [12]

The Interaction Atlas With This Target

The Protein(s) Related To This Target

Enzyme
Click To Hide/Show 2 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
COP9 signalosome complex subunit 3 (COPS3) CSN3 family Q9UNS2
Dual specificity phosphatase 29 (DUSP29) Protein-tyrosine phosphatase family Q68J44
Other
Click To Hide/Show 1 Protein(s) Interacting with This Target
Protein name Family Uniprot ID
LRP chaperone MESD (MESD) MESD family Q14696

References

1 Quantitative and Site-Specific Chemoproteomic Profiling of Targets of Acrolein. Chem Res Toxicol. 2019 Mar 18;32(3):467-473. doi: 10.1021/acs.chemrestox.8b00343. Epub 2019 Jan 15.
2 Nucleophilic covalent ligand discovery for the cysteine redoxome. Nat Chem Biol. 2023 Nov;19(11):1309-1319. doi: 10.1038/s41589-023-01330-5. Epub 2023 May 29.
Mass spectrometry data entry: PXD039908 , PXD029761
3 N-Acryloylindole-alkyne (NAIA) enables imaging and profiling new ligandable cysteines and oxidized thiols by chemoproteomics. Nat Commun. 2023 Jun 15;14(1):3564. doi: 10.1038/s41467-023-39268-w.
Mass spectrometry data entry: PXD041264
4 Chemoproteomic capture of RNA binding activity in living cells. Nat Commun. 2023 Oct 7;14(1):6282. doi: 10.1038/s41467-023-41844-z.
Mass spectrometry data entry: PXD044625
5 Covalent Inhibition by a Natural Product-Inspired Latent Electrophile. J Am Chem Soc. 2023 May 24;145(20):11097-11109. doi: 10.1021/jacs.3c00598. Epub 2023 May 15.
6 Enhancing Cysteine Chemoproteomic Coverage through Systematic Assessment of Click Chemistry Product Fragmentation. Anal Chem. 2022 Mar 8;94(9):3800-3810. doi: 10.1021/acs.analchem.1c04402. Epub 2022 Feb 23.
Mass spectrometry data entry: PXD028853
7 A modification-centric assessment tool for the performance of chemoproteomic probes. Nat Chem Biol. 2022 Aug;18(8):904-912. doi: 10.1038/s41589-022-01074-8. Epub 2022 Jul 21.
Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
8 Chemoproteomic Profiling by Cysteine Fluoroalkylation Reveals Myrocin G as an Inhibitor of the Nonhomologous End Joining DNA Repair Pathway. J Am Chem Soc. 2021 Dec 8;143(48):20332-20342. doi: 10.1021/jacs.1c09724. Epub 2021 Nov 24.
Mass spectrometry data entry: PXD029255
9 Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe. Redox Biol. 2017 Aug;12:712-718. doi: 10.1016/j.redox.2017.04.001. Epub 2017 Apr 5.
10 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587
11 Rapamycin targets STAT3 and impacts c-Myc to suppress tumor growth. Cell Chem Biol. 2022 Mar 17;29(3):373-385.e6. doi: 10.1016/j.chembiol.2021.10.006. Epub 2021 Oct 26.
12 Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4.
13 Accelerating multiplexed profiling of protein-ligand interactions: High-throughput plate-based reactive cysteine profiling with minimal input. Cell Chem Biol. 2024 Mar 21;31(3):565-576.e4. doi: 10.1016/j.chembiol.2023.11.015. Epub 2023 Dec 19.
Mass spectrometry data entry: PXD044402
14 Site-specific quantitative cysteine profiling with data-independent acquisition-based mass spectrometry. Methods Enzymol. 2023;679:295-322. doi: 10.1016/bs.mie.2022.07.037. Epub 2022 Sep 7.
Mass spectrometry data entry: PXD027578
15 DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell. 2024 May 9;187(10):2536-2556.e30. doi: 10.1016/j.cell.2024.03.027. Epub 2024 Apr 22.
Mass spectrometry data entry: PXD047840
16 Rapid Covalent-Probe Discovery by Electrophile-Fragment Screening. J Am Chem Soc. 2019 Jun 5;141(22):8951-8968. doi: 10.1021/jacs.9b02822. Epub 2019 May 22.
17 Physical and Functional Analysis of the Putative Rpn13 Inhibitor RA190. Cell Chem Biol. 2020 Nov 19;27(11):1371-1382.e6. doi: 10.1016/j.chembiol.2020.08.007. Epub 2020 Aug 27.