Details of the Target

General Information of Target

Target ID LDTP18561
Target Name Small ribosomal subunit protein mS33 (MRPS33)
Gene Name MRPS33
Gene ID 51650
Synonyms
Small ribosomal subunit protein mS33; 28S ribosomal protein S33, mitochondrial; MRP-S33; S33mt
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MPLVEETSLLEDSSVTFPVVIIGNGPSGICLSYMLSGYRPYLSSEAIHPNTILNSKLEEA
RHLSIVDQDLEYLSEGLEGRSSNPVAVLFDTLLHPDADFGYDYPSVLHWKLEQHHYIPHV
VLGKGPPGGAWHNMEGSMLTISFGSWMELPGLKFKDWVSSKRRSLKGDRVMPEEIARYYK
HYVKVMGLQKNFRENTYITSVSRLYRDQDDDDIQDRDISTKHLQIEKSNFIKRNWEIRGY
QRIADGSHVPFCLFAENVALATGTLDSPAHLEIEGEDFPFVFHSMPEFGAAINKGKLRGK
VDPVLIVGSGLTAADAVLCAYNSNIPVIHVFRRRVTDPSLIFKQLPKKLYPEYHKVYHMM
CTQSYSVDSNLLSDYTSFPEHRVLSFKSDMKCVLQSVSGLKKIFKLSAAVVLIGSHPNLS
FLKDQGCYLGHKSSQPITCKGNPVEIDTYTYECIKEANLFALGPLVGDNFVRFLKGGALG
VTRCLATRQKKKHLFVERGGGDGIA
Target Bioclass
Other
Family
Mitochondrion-specific ribosomal protein mS33 family
Subcellular location
Mitochondrion
Uniprot ID
Q9Y291
Ensemble ID
ENST00000324787.10
HGNC ID
HGNC:16634

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 3 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
STPyne
 Probe Info  		K35(9.29)  LDD0277  [1]
ATP probe
 Probe Info  		N.A.  LDD0199  [2]
1c-yne
 Probe Info  		N.A.  LDD0228  [3]
PAL-AfBPP Probe
Click To Hide/Show 7 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C001
 Probe Info  		4.99  LDD1711  [4]
C191
 Probe Info  		11.31  LDD1868  [4]
C196
 Probe Info  		13.18  LDD1872  [4]
C197
 Probe Info  		6.59  LDD1873  [4]
C228
 Probe Info  		14.93  LDD1901  [4]
C286
 Probe Info  		70.03  LDD1956  [4]
C431
 Probe Info  		16.68  LDD2086  [4]

References

1 A Paal-Knorr agent for chemoproteomic profiling of targets of isoketals in cells. Chem Sci. 2021 Oct 15;12(43):14557-14563. doi: 10.1039/d1sc02230j. eCollection 2021 Nov 10.
Mass spectrometry data entry: PXD028270
2 Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases. J Proteome Res. 2022 Aug 5;21(8):2063-2070. doi: 10.1021/acs.jproteome.2c00225. Epub 2022 Jul 12.
3 Tunable Amine-Reactive Electrophiles for Selective Profiling of Lysine. Angew Chem Int Ed Engl. 2022 Jan 26;61(5):e202112107. doi: 10.1002/anie.202112107. Epub 2021 Dec 16.
4 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587