Details of the Probe

General Information of Probe

Probe ID
LDPC0516
Probe Name
C286
Synonyms
Z4282860726
Probe Type
PAL-AfBPP Probe
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 369.5
Lipid-water partition coefficient (xlogp) 2.4
Rotatable Bond Count (rotbonds) 8
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C21H27N3O3
IUPAC Name
3-(3-but-3-ynyldiazirin-3-yl)-1-[4-[hydroxy-(3-methoxyphenyl)methyl]piperidin-1-yl]propan-1-one
Canonical SMILES
COC1=CC=CC(=C1)C(C2CCN(CC2)C(=O)CCC3(N=N3)CCC#C)O
InChI
InChI=1S/C21H27N3O3/c1-3-4-11-21(22-23-21)12-8-19(25)24-13-9-16(10-14-24)20(26)17-6-5-7-18(15-17)27-2/h1,5-7,15-16,20,26H,4,8-14H2,2H3
InChIKey
LICSMZYROYTHSV-UHFFFAOYSA-N

The Probe Interaction Atlas

Target(s) List of this Probe

126 Enzyme Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 5.17  LDD1956 
3-ketodihydrosphingosine reductase (KDSR) LDTP05476 5.17  LDD1956 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 7.67  LDD1956 
7-methylguanosine phosphate-specific 5'-nucleotidase (NT5C3B) LDTP10032 7.67  LDD1956 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 5.74  LDD1956 
ADP-ribosylation factor-like protein 10 (ARL10) LDTP19745 5.74  LDD1956 
Amidophosphoribosyltransferase (PPAT) LDTP05480 7.46  LDD1956 
Amidophosphoribosyltransferase (PPAT) LDTP05480 7.46  LDD1956 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 8.69  LDD1956 
ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) LDTP06618 8.69  LDD1956 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 5.66  LDD1956 
Bis(monoacylglycero)phosphate synthase CLN5 (CLN5) LDTP01241 5.66  LDD1956 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 6.50  LDD1956 
Carbohydrate sulfotransferase 14 (CHST14) LDTP09096 6.50  LDD1956 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 5.31  LDD1956 
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) LDTP03257 5.31  LDD1956 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 6.28  LDD1956 
CDGSH iron-sulfur domain-containing protein 1 (CISD1) LDTP12873 6.28  LDD1956 
Cytochrome b5 type B (CYB5B) LDTP00697 5.13  LDD1956 
Cytochrome b5 type B (CYB5B) LDTP00697 5.13  LDD1956 
DCN1-like protein 4 (DCUN1D4) LDTP09799 5.39  LDD1956 
DCN1-like protein 4 (DCUN1D4) LDTP09799 5.39  LDD1956 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 24.93  LDD1956 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 24.93  LDD1956 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 7.78  LDD1956 
Delta(14)-sterol reductase LBR (LBR) LDTP06200 7.78  LDD1956 
Delta(24)-sterol reductase (DHCR24) LDTP06375 7.57  LDD1956 
Delta(24)-sterol reductase (DHCR24) LDTP06375 7.57  LDD1956 
Dihydrofolate reductase (DHFR) LDTP01769 4.96  LDD1956 
Dihydrofolate reductase (DHFR) LDTP01769 4.96  LDD1956 
E3 ubiquitin-protein ligase TRIM21 (TRIM21) LDTP03001 6.15  LDD1956 
E3 ubiquitin-protein ligase TRIM21 (TRIM21) LDTP03001 6.15  LDD1956 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 8.22  LDD1956 
Endoplasmic reticulum aminopeptidase 1 (ERAP1) LDTP12868 8.22  LDD1956 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 5.43  LDD1956 
Endoplasmic reticulum transmembrane helix translocase (ATP13A1) LDTP12279 5.43  LDD1956 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 6.19  LDD1956 
Endothelin-converting enzyme 1 (ECE1) LDTP04008 6.19  LDD1956 
Epoxide hydrolase 1 (EPHX1) LDTP02175 6.50  LDD1956 
Epoxide hydrolase 1 (EPHX1) LDTP02175 6.50  LDD1956 
Ethanolamine kinase 1 (ETNK1) LDTP12197 7.73  LDD1956 
Ethanolamine kinase 1 (ETNK1) LDTP12197 7.73  LDD1956 
Exonuclease 1 (EXO1) LDTP13751 6.15  LDD1956 
Exonuclease 1 (EXO1) LDTP13751 6.15  LDD1956 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 5.70  LDD1956 
FAD-dependent oxidoreductase domain-containing protein 1 (FOXRED1) LDTP10188 5.70  LDD1956 
Heme oxygenase 2 (HMOX2) LDTP03540 7.62  LDD1956 
Heme oxygenase 2 (HMOX2) LDTP03540 7.62  LDD1956 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 5.82  LDD1956 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 5.82  LDD1956 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 7.36  LDD1956 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 7.36  LDD1956 
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) LDTP04211 11.24  LDD1956 
Isocitrate dehydrogenase [NADP], mitochondrial (IDH2) LDTP04211 11.24  LDD1956 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 7.11  LDD1956 
Lanosterol 14-alpha demethylase (CYP51A1) LDTP06648 7.11  LDD1956 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 6.41  LDD1956 
Leucyl-cystinyl aminopeptidase (LNPEP) LDTP13358 6.41  LDD1956 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 7.89  LDD1956 
Long-chain-fatty-acid--CoA ligase 6 (ACSL6) LDTP13486 7.89  LDD1956 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 6.06  LDD1956 
Lysosomal acid glucosylceramidase (GBA1) LDTP02005 6.06  LDD1956 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 8.94  LDD1956 
Lysosomal Pro-X carboxypeptidase (PRCP) LDTP04004 8.94  LDD1956 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 6.68  LDD1956 
Lysosomal thioesterase PPT2 (PPT2) LDTP13620 6.68  LDD1956 
Macrophage migration inhibitory factor (MIF) LDTP02713 23.75  LDD1956 
Macrophage migration inhibitory factor (MIF) LDTP02713 23.75  LDD1956 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 10.41  LDD1956 
Methylsterol monooxygenase 1 (MSMO1) LDTP06477 10.41  LDD1956 
Mevalonate kinase (MVK) LDTP05405 4.99  LDD1956 
Mevalonate kinase (MVK) LDTP05405 4.99  LDD1956 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 6.54  LDD1956 
Mitochondrial cardiolipin hydrolase (PLD6) LDTP08790 6.54  LDD1956 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 5.58  LDD1956 
NAD(P) transhydrogenase, mitochondrial (NNT) LDTP05862 5.58  LDD1956 
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) LDTP08598 18.25  LDD1956 
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) LDTP08598 18.25  LDD1956 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 18.51  LDD1956 
NADH dehydrogenase 1 beta subcomplex subunit 3 (NDUFB3) LDTP00832 18.51  LDD1956 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 7.73  LDD1956 
NADH-ubiquinone oxidoreductase chain 1 (MT-ND1) LDTP01982 7.73  LDD1956 
Nardilysin (NRDC) LDTP00886 6.73  LDD1956 
Nardilysin (NRDC) LDTP00886 6.73  LDD1956 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 16.45  LDD1956 
Nicotinamide phosphoribosyltransferase (NAMPT) LDTP04051 16.45  LDD1956 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 12.82  LDD1956 
Palmitoyl-protein thioesterase 1 (PPT1) LDTP04388 12.82  LDD1956 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 8.28  LDD1956 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 8.28  LDD1956 
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2) LDTP06638 7.46  LDD1956 
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2) LDTP06638 7.46  LDD1956 
Phospholipase A2 group XV (PLA2G15) LDTP09088 6.73  LDD1956 
Phospholipase A2 group XV (PLA2G15) LDTP09088 6.73  LDD1956 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 13.64  LDD1956 
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) LDTP08859 13.64  LDD1956 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 6.32  LDD1956 
Prenylcysteine oxidase 1 (PCYOX1) LDTP13282 6.32  LDD1956 
Prostaglandin reductase 1 (PTGR1) LDTP06227 13.55  LDD1956 
Prostaglandin reductase 1 (PTGR1) LDTP06227 13.55  LDD1956 
Prostaglandin reductase 3 (PTGR3) LDTP15422 11.16  LDD1956 
Prostaglandin reductase 3 (PTGR3) LDTP15422 11.16  LDD1956 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 7.16  LDD1956 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 7.16  LDD1956 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 10.56  LDD1956 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 10.56  LDD1956 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 8.75  LDD1956 
Protein farnesyltransferase subunit beta (FNTB) LDTP04247 8.75  LDD1956 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 11.24  LDD1956 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 11.24  LDD1956 
Pseudouridine-5'-phosphatase (PUDP) LDTP05568 7.46  LDD1956 
Pseudouridine-5'-phosphatase (PUDP) LDTP05568 7.46  LDD1956 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 5.03  LDD1956 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 5.03  LDD1956 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 6.63  LDD1956 
Reticulon-4-interacting protein 1, mitochondrial (RTN4IP1) LDTP09666 6.63  LDD1956 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 13.45  LDD1956 
Retinoid-inducible serine carboxypeptidase (SCPEP1) LDTP16032 13.45  LDD1956 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 7.94  LDD1956 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 7.94  LDD1956 
Sepiapterin reductase (SPR) LDTP03730 16.68  LDD1956 
Sepiapterin reductase (SPR) LDTP03730 16.68  LDD1956 
TLC domain-containing protein 1 (TLCD1) LDTP10182 7.26  LDD1956 
TLC domain-containing protein 1 (TLCD1) LDTP10182 7.26  LDD1956 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 13.74  LDD1956 
V-type proton ATPase 116 kDa subunit a 2 (ATP6V0A2) LDTP14030 13.74  LDD1956 
------------------------------------------------------------------------------------
⏷ Show the Full List of 126 Enzyme
80 Transporter and channel Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 7.84  LDD1956 
Acetyl-coenzyme A transporter 1 (SLC33A1) LDTP00262 7.84  LDD1956 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 8.94  LDD1956 
ATP synthase subunit g, mitochondrial (ATP5MG) LDTP14511 8.94  LDD1956 
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (COX16) LDTP16163 6.63  LDD1956 
Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (COX16) LDTP16163 6.63  LDD1956 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 9.65  LDD1956 
ER lumen protein-retaining receptor 1 (KDELR1) LDTP03277 9.65  LDD1956 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 5.39  LDD1956 
Growth hormone-inducible transmembrane protein (GHITM) LDTP11869 5.39  LDD1956 
Lysosomal-associated transmembrane protein 4A (LAPTM4A) LDTP06275 5.86  LDD1956 
Lysosomal-associated transmembrane protein 4A (LAPTM4A) LDTP06275 5.86  LDD1956 
Lysosome membrane protein 2 (SCARB2) LDTP06034 4.99  LDD1956 
Lysosome membrane protein 2 (SCARB2) LDTP06034 4.99  LDD1956 
Methylosome subunit pICln (CLNS1A) LDTP04597 5.13  LDD1956 
Methylosome subunit pICln (CLNS1A) LDTP04597 5.13  LDD1956 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 7.41  LDD1956 
Mitochondrial carnitine/acylcarnitine carrier protein (SLC25A20) LDTP00865 7.41  LDD1956 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 8.06  LDD1956 
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) LDTP10913 8.06  LDD1956 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 10.06  LDD1956 
Mitochondrial import inner membrane translocase subunit Tim17-B (TIMM17B) LDTP01059 10.06  LDD1956 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 5.06  LDD1956 
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) LDTP14099 5.06  LDD1956 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 5.82  LDD1956 
Mitochondrial import inner membrane translocase subunit Tim23 (TIMM23) LDTP00477 5.82  LDD1956 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 7.21  LDD1956 
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) LDTP07885 7.21  LDD1956 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 5.17  LDD1956 
NPC intracellular cholesterol transporter 1 (NPC1) LDTP00541 5.17  LDD1956 
Nuclear pore complex protein Nup107 (NUP107) LDTP04800 7.31  LDD1956 
Nuclear pore complex protein Nup107 (NUP107) LDTP04800 7.31  LDD1956 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 8.00  LDD1956 
Peroxisomal membrane protein 2 (PXMP2) LDTP16069 8.00  LDD1956 
Prosaposin (PSAP) LDTP02215 5.82  LDD1956 
Prosaposin (PSAP) LDTP02215 5.82  LDD1956 
Protein GPR107 (GPR107) LDTP07236 19.29  LDD1956 
Protein GPR107 (GPR107) LDTP07236 19.29  LDD1956 
Protein GPR108 (GPR108) LDTP12383 9.71  LDD1956 
Protein GPR108 (GPR108) LDTP12383 9.71  LDD1956 
Protein spinster homolog 1 (SPNS1) LDTP11844 7.26  LDD1956 
Protein spinster homolog 1 (SPNS1) LDTP11844 7.26  LDD1956 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 14.42  LDD1956 
Scavenger receptor class B member 1 (SCARB1) LDTP09547 14.42  LDD1956 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 5.24  LDD1956 
Sigma non-opioid intracellular receptor 1 (SIGMAR1) LDTP10958 5.24  LDD1956 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 16.34  LDD1956 
Solute carrier family 25 member 44 (SLC25A44) LDTP15733 16.34  LDD1956 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 5.58  LDD1956 
Solute carrier family 35 member F2 (SLC35F2) LDTP17641 5.58  LDD1956 
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (SDHC) LDTP10931 6.02  LDD1956 
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (SDHC) LDTP10931 6.02  LDD1956 
Tetraspanin-3 (TSPAN3) LDTP16813 6.92  LDD1956 
Tetraspanin-3 (TSPAN3) LDTP16813 6.92  LDD1956 
THO complex subunit 1 (THOC1) LDTP10317 10.63  LDD1956 
THO complex subunit 1 (THOC1) LDTP10317 10.63  LDD1956 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 6.32  LDD1956 
Translocating chain-associated membrane protein 1 (TRAM1) LDTP06426 6.32  LDD1956 
Translocator protein (TSPO) LDTP03546 6.45  LDD1956 
Translocator protein (TSPO) LDTP03546 6.45  LDD1956 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 5.90  LDD1956 
Translocon-associated protein subunit alpha (SSR1) LDTP04033 5.90  LDD1956 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 6.87  LDD1956 
Transmembrane 9 superfamily member 3 (TM9SF3) LDTP18448 6.87  LDD1956 
Transmembrane protein 126A (TMEM126A) LDTP15948 7.46  LDD1956 
Transmembrane protein 126A (TMEM126A) LDTP15948 7.46  LDD1956 
Transmembrane protein 160 (TMEM160) LDTP20002 14.62  LDD1956 
Transmembrane protein 160 (TMEM160) LDTP20002 14.62  LDD1956 
Transmembrane protein 199 (TMEM199) LDTP08881 6.82  LDD1956 
Transmembrane protein 199 (TMEM199) LDTP08881 6.82  LDD1956 
Transmembrane protein 205 (TMEM205) LDTP07667 8.17  LDD1956 
Transmembrane protein 205 (TMEM205) LDTP07667 8.17  LDD1956 
Transmembrane protein 87A (TMEM87A) LDTP15481 5.94  LDD1956 
Transmembrane protein 87A (TMEM87A) LDTP15481 5.94  LDD1956 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 15.78  LDD1956 
V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1) LDTP09968 15.78  LDD1956 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 19.03  LDD1956 
Voltage-dependent anion-selective channel protein 1 (VDAC1) LDTP03132 19.03  LDD1956 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 10.06  LDD1956 
Voltage-dependent anion-selective channel protein 2 (VDAC2) LDTP04071 10.06  LDD1956 
------------------------------------------------------------------------------------
⏷ Show the Full List of 80 Transporter and channel
84 Other Labeled by This Probe
Target Name Target ID Binding Site(Ratio) Interaction ID
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 7.26  LDD1956 
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) LDTP08364 7.26  LDD1956 
Apolipoprotein L2 (APOL2) LDTP11076 5.35  LDD1956 
Apolipoprotein L2 (APOL2) LDTP11076 5.35  LDD1956 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 10.34  LDD1956 
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAIAP2) LDTP13755 10.34  LDD1956 
BRISC and BRCA1-A complex member 1 (BABAM1) LDTP12737 6.87  LDD1956 
BRISC and BRCA1-A complex member 1 (BABAM1) LDTP12737 6.87  LDD1956 
Cell division cycle-associated protein 2 (CDCA2) LDTP07345 8.22  LDD1956 
Cell division cycle-associated protein 2 (CDCA2) LDTP07345 8.22  LDD1956 
Centrosomal protein of 44 kDa (CEP44) LDTP11611 5.03  LDD1956 
Centrosomal protein of 44 kDa (CEP44) LDTP11611 5.03  LDD1956 
Clustered mitochondria protein homolog (CLUH) LDTP14486 9.38  LDD1956 
Clustered mitochondria protein homolog (CLUH) LDTP14486 9.38  LDD1956 
Cobalamin trafficking protein CblD (MMADHC) LDTP11871 8.28  LDD1956 
Cobalamin trafficking protein CblD (MMADHC) LDTP11871 8.28  LDD1956 
Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1) LDTP14250 10.13  LDD1956 
Cytoplasmic dynein 1 light intermediate chain 1 (DYNC1LI1) LDTP14250 10.13  LDD1956 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 6.50  LDD1956 
Dyslexia-associated protein KIAA0319-like protein (KIAA0319L) LDTP08689 6.50  LDD1956 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 6.82  LDD1956 
ER lumen protein-retaining receptor 3 (KDELR3) LDTP00850 6.82  LDD1956 
Gem-associated protein 8 (GEMIN8) LDTP12746 6.41  LDD1956 
Gem-associated protein 8 (GEMIN8) LDTP12746 6.41  LDD1956 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 5.98  LDD1956 
HAUS augmin-like complex subunit 4 (HAUS4) LDTP11978 5.98  LDD1956 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 5.58  LDD1956 
Heterogeneous nuclear ribonucleoprotein D-like (HNRNPDL) LDTP00500 5.58  LDD1956 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 5.46  LDD1956 
Heterogeneous nuclear ribonucleoprotein H3 (HNRNPH3) LDTP03614 5.46  LDD1956 
Large proline-rich protein BAG6 (BAG6) LDTP04094 8.51  LDD1956 
Large proline-rich protein BAG6 (BAG6) LDTP04094 8.51  LDD1956 
Large ribosomal subunit protein uL13m (MRPL13) LDTP15915 6.63  LDD1956 
Large ribosomal subunit protein uL13m (MRPL13) LDTP15915 6.63  LDD1956 
MAGUK p55 subfamily member 2 (MPP2) LDTP06068 13.93  LDD1956 
MAGUK p55 subfamily member 2 (MPP2) LDTP06068 13.93  LDD1956 
Mdm2-binding protein (MTBP) LDTP15714 5.24  LDD1956 
Mdm2-binding protein (MTBP) LDTP15714 5.24  LDD1956 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 7.46  LDD1956 
Mitochondrial import receptor subunit TOM22 homolog (TOMM22) LDTP12565 7.46  LDD1956 
Negative elongation factor C/D (NELFCD) LDTP08594 6.23  LDD1956 
Negative elongation factor C/D (NELFCD) LDTP08594 6.23  LDD1956 
Neuferricin (CYB5D2) LDTP15623 5.17  LDD1956 
Neuferricin (CYB5D2) LDTP15623 5.17  LDD1956 
Nucleobindin-2 (NUCB2) LDTP05160 8.57  LDD1956 
Nucleobindin-2 (NUCB2) LDTP05160 8.57  LDD1956 
Optic atrophy 3 protein (OPA3) LDTP16006 15.45  LDD1956 
Optic atrophy 3 protein (OPA3) LDTP16006 15.45  LDD1956 
Peroxisomal membrane protein 11C (PEX11G) LDTP10381 19.84  LDD1956 
Peroxisomal membrane protein 11C (PEX11G) LDTP10381 19.84  LDD1956 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 63.12  LDD1956 
Poly(U)-binding-splicing factor PUF60 (PUF60) LDTP13311 63.12  LDD1956 
Programmed cell death protein 5 (PDCD5) LDTP00417 10.78  LDD1956 
Programmed cell death protein 5 (PDCD5) LDTP00417 10.78  LDD1956 
Protein CutA (CUTA) LDTP01075 7.89  LDD1956 
Protein CutA (CUTA) LDTP01075 7.89  LDD1956 
Protein Hikeshi (HIKESHI) LDTP06892 15.78  LDD1956 
Protein Hikeshi (HIKESHI) LDTP06892 15.78  LDD1956 
Protein PALS2 (PALS2) LDTP16156 8.00  LDD1956 
Protein PALS2 (PALS2) LDTP16156 8.00  LDD1956 
Protein TASOR (TASOR) LDTP13430 6.45  LDD1956 
Protein TASOR (TASOR) LDTP13430 6.45  LDD1956 
Protein unc-119 homolog B (UNC119B) LDTP00105 7.78  LDD1956 
Protein unc-119 homolog B (UNC119B) LDTP00105 7.78  LDD1956 
Protein YIF1B (YIF1B) LDTP06948 4.99  LDD1956 
Protein YIF1B (YIF1B) LDTP06948 4.99  LDD1956 
Retinol-binding protein 1 (RBP1) LDTP02345 5.70  LDD1956 
Retinol-binding protein 1 (RBP1) LDTP02345 5.70  LDD1956 
Rho GTPase-activating protein 17 (ARHGAP17) LDTP07335 7.52  LDD1956 
Rho GTPase-activating protein 17 (ARHGAP17) LDTP07335 7.52  LDD1956 
RNA-binding protein FUS (FUS) LDTP03775 6.32  LDD1956 
RNA-binding protein FUS (FUS) LDTP03775 6.32  LDD1956 
RNA-binding protein with multiple splicing (RBPMS) LDTP09970 4.96  LDD1956 
RNA-binding protein with multiple splicing (RBPMS) LDTP09970 4.96  LDD1956 
Small ribosomal subunit protein mS33 (MRPS33) LDTP18561 70.03  LDD1956 
Small ribosomal subunit protein mS33 (MRPS33) LDTP18561 70.03  LDD1956 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 5.10  LDD1956 
TATA-binding protein-associated factor 2N (TAF15) LDTP09881 5.10  LDD1956 
Trophoblast glycoprotein (TPBG) LDTP05960 5.28  LDD1956 
Trophoblast glycoprotein (TPBG) LDTP05960 5.28  LDD1956 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 5.24  LDD1956 
Ubiquinol-cytochrome c reductase complex assembly factor 5 (UQCC5) LDTP15634 5.24  LDD1956 
Wings apart-like protein homolog (WAPL) LDTP08094 5.03  LDD1956 
Wings apart-like protein homolog (WAPL) LDTP08094 5.03  LDD1956 
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Full Information of The Labelling Profiles of This Probe

Quantification: AfBPP Probe vs Negative Probe
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration
Probe:50uM; negative probe:50uM
Quantitative Method
TMT
In Vitro Experiment Model
Model Type
Living cell
Derived Tissue
Peripheral blood
Disease Model
Normal
Model Name
Human normal cells (HEK-293T)
Note
Negative probe:C#CCCC1(CCC(NC)=O)N=N1
Interaction Atlas ID
 LDD1956 
Download The Altas

References

1 Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26.
Mass spectrometry data entry: PXD041587