Details of the Target

General Information of Target

Target ID LDTP05480
Target Name Amidophosphoribosyltransferase (PPAT)
Gene Name PPAT
Gene ID 5471
Synonyms
GPAT; Amidophosphoribosyltransferase; ATase; EC 2.4.2.14; Glutamine phosphoribosylpyrophosphate amidotransferase; GPAT
3D Structure
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2D Sequence (FASTA)
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3D Structure (PDB)
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Sequence
MELEELGIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPT
FKSHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVA
HNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEA
PTAYSLLIMHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFL
SIGARYYREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVY
TVRYRCGQQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQP
NMRLRQLGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASP
PIKYPCFMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQKE
KKHDIMIQENGNGLECFEKSGHCTACLTGKYPVELEW
Target Type
Successful
Target Bioclass
Enzyme
Family
Purine/pyrimidine phosphoribosyltransferase family
Function Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
TTD ID
T97713
Uniprot ID
Q06203
DrugMap ID
TTZFTY4
Ensemble ID
ENST00000264220.6
HGNC ID
HGNC:9238
ChEMBL ID
CHEMBL2362992

Probe(s) Labeling This Target

ABPP Probe
Click To Hide/Show 31 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
m-APA
 Probe Info  		15.00  LDD0402  [1]
TH211
 Probe Info  		Y157(20.00); Y94(7.33)  LDD0257  [2]
YN-1
 Probe Info  		100.00  LDD0444  [3]
STPyne
 Probe Info  		K372(0.90); K403(10.00)  LDD0277  [4]
Probe 1
 Probe Info  		Y94(104.67)  LDD3495  [5]
Dasatinib-CA-4PAP
 Probe Info  		6.00  LDD0270  [6]
BTD
 Probe Info  		C207(0.85)  LDD2101  [7]
DA-P3
 Probe Info  		9.83  LDD0183  [8]
AHL-Pu-1
 Probe Info  		C503(2.13); C105(9.34)  LDD0169  [9]
EA-probe
 Probe Info  		N.A.  LDD0440  [10]
HHS-482
 Probe Info  		Y94(0.94)  LDD0285  [11]
HHS-475
 Probe Info  		Y246(1.05); Y451(10.76)  LDD0266  [12]
HHS-465
 Probe Info  		Y94(8.42)  LDD2237  [13]
DBIA
 Probe Info  		C100(1.01); C105(1.01); C426(0.97)  LDD0078  [14]
5E-2FA
 Probe Info  		N.A.  LDD2235  [15]
AMP probe
 Probe Info  		N.A.  LDD0200  [16]
ATP probe
 Probe Info  		K349(0.00); K372(0.00); K220(0.00); K222(0.00)  LDD0199  [16]
4-Iodoacetamidophenylacetylene
 Probe Info  		C207(0.00); C496(0.00); C426(0.00); C503(0.00)  LDD0038  [17]
IA-alkyne
 Probe Info  		C100(0.00); C339(0.00)  LDD0032  [18]
IPIAA_L
 Probe Info  		N.A.  LDD0031  [19]
Lodoacetamide azide
 Probe Info  		C348(0.00); C339(0.00); C306(0.00); C207(0.00)  LDD0037  [17]
NAIA_4
 Probe Info  		C100(0.00); C496(0.00)  LDD2226  [20]
aHNE
 Probe Info  		N.A.  LDD0001  [21]
Compound 10
 Probe Info  		N.A.  LDD2216  [22]
Compound 11
 Probe Info  		N.A.  LDD2213  [22]
IPM
 Probe Info  		N.A.  LDD0005  [21]
VSF
 Probe Info  		N.A.  LDD0007  [21]
Phosphinate-6
 Probe Info  		N.A.  LDD0018  [23]
1c-yne
 Probe Info  		N.A.  LDD0228  [24]
AOyne
 Probe Info  		12.60  LDD0443  [25]
NAIA_5
 Probe Info  		C306(0.00); C207(0.00); C426(0.00)  LDD2223  [20]
PAL-AfBPP Probe
Click To Hide/Show 12 Probe Related to This Target
Probe name Structure Binding Site(Ratio) Interaction ID Ref
C178
 Probe Info  		19.43  LDD1857  [26]
C187
 Probe Info  		17.75  LDD1865  [26]
C191
 Probe Info  		32.00  LDD1868  [26]
C218
 Probe Info  		16.56  LDD1892  [26]
C277
 Probe Info  		8.00  LDD1947  [26]
C286
 Probe Info  		7.46  LDD1956  [26]
C383
 Probe Info  		18.13  LDD2042  [26]
C403
 Probe Info  		14.93  LDD2061  [26]
FFF probe13
 Probe Info  		16.05  LDD0475  [27]
FFF probe14
 Probe Info  		12.36  LDD0477  [27]
FFF probe2
 Probe Info  		5.70  LDD0463  [27]
OEA-DA
 Probe Info  		3.40  LDD0046  [28]

Competitor(s) Related to This Target

Competitor ID Name Cell line Binding Site(Ratio) Interaction ID Ref
 LDCM0524  2-Cyano-N-(2-morpholin-4-yl-ethyl)-acetamide MDA-MB-231 C207(0.55)  LDD2117  [7]
 LDCM0558  2-Cyano-N-phenylacetamide MDA-MB-231 C207(1.24)  LDD2152  [7]
 LDCM0539  3-(4-Isopropylpiperazin-1-yl)-3-oxopropanenitrile MDA-MB-231 C506(0.56)  LDD2132  [7]
 LDCM0025  4SU-RNA DM93 C506(2.16)  LDD0170  [9]
 LDCM0026  4SU-RNA+native RNA HEK-293T C503(2.13); C105(9.34)  LDD0169  [9]
 LDCM0214  AC1 HCT 116 C105(1.43); C100(1.39); C339(0.82); C348(0.82)  LDD0531  [14]
 LDCM0215  AC10 HCT 116 C105(1.38); C100(1.37); C339(1.14); C348(1.13)  LDD0532  [14]
 LDCM0216  AC100 HCT 116 C105(1.08); C100(1.07); C339(1.01); C348(0.99)  LDD0533  [14]
 LDCM0217  AC101 HCT 116 C105(1.02); C100(1.10); C339(0.98); C348(0.99)  LDD0534  [14]
 LDCM0218  AC102 HCT 116 C105(0.96); C100(0.98); C339(1.03); C348(0.99)  LDD0535  [14]
 LDCM0219  AC103 HCT 116 C105(1.24); C100(1.25); C339(1.09); C348(1.07)  LDD0536  [14]
 LDCM0220  AC104 HCT 116 C105(1.03); C100(1.05); C339(1.06); C348(1.04)  LDD0537  [14]
 LDCM0221  AC105 HCT 116 C105(1.17); C100(1.21); C339(1.10); C348(1.08)  LDD0538  [14]
 LDCM0222  AC106 HCT 116 C105(1.07); C100(1.11); C339(1.18); C348(1.13)  LDD0539  [14]
 LDCM0223  AC107 HCT 116 C105(1.10); C100(1.22); C339(1.15); C348(1.20)  LDD0540  [14]
 LDCM0224  AC108 HCT 116 C105(1.17); C100(1.05); C339(1.01); C348(0.99)  LDD0541  [14]
 LDCM0225  AC109 HCT 116 C105(0.99); C100(0.93); C339(0.95); C348(0.93)  LDD0542  [14]
 LDCM0226  AC11 HCT 116 C105(1.25); C100(1.21); C339(1.04); C348(1.05)  LDD0543  [14]
 LDCM0227  AC110 HCT 116 C105(1.08); C100(1.04); C339(1.05); C348(1.00)  LDD0544  [14]
 LDCM0228  AC111 HCT 116 C105(1.03); C100(1.06); C339(1.06); C348(0.93)  LDD0545  [14]
 LDCM0229  AC112 HCT 116 C105(1.09); C100(1.11); C339(1.15); C348(1.24)  LDD0546  [14]
 LDCM0230  AC113 HCT 116 C105(1.03); C100(1.05); C339(0.97); C348(0.97)  LDD0547  [14]
 LDCM0231  AC114 HCT 116 C105(0.97); C100(1.11); C339(1.13); C348(1.15)  LDD0548  [14]
 LDCM0232  AC115 HCT 116 C105(1.18); C100(1.18); C339(1.24); C348(1.26)  LDD0549  [14]
 LDCM0233  AC116 HCT 116 C105(1.16); C100(1.25); C339(1.13); C348(1.14)  LDD0550  [14]
 LDCM0234  AC117 HCT 116 C105(1.08); C100(1.16); C339(1.14); C348(1.15)  LDD0551  [14]
 LDCM0235  AC118 HCT 116 C105(1.13); C100(1.12); C339(1.02); C348(1.00)  LDD0552  [14]
 LDCM0236  AC119 HCT 116 C105(1.06); C100(1.07); C339(1.27); C348(1.30)  LDD0553  [14]
 LDCM0237  AC12 HCT 116 C105(1.08); C100(1.04); C339(1.05); C348(1.03)  LDD0554  [14]
 LDCM0238  AC120 HCT 116 C105(1.13); C100(1.14); C339(1.05); C348(1.06)  LDD0555  [14]
 LDCM0239  AC121 HCT 116 C105(1.15); C100(1.16); C339(1.09); C348(1.06)  LDD0556  [14]
 LDCM0240  AC122 HCT 116 C105(1.14); C100(1.09); C339(1.14); C348(1.13)  LDD0557  [14]
 LDCM0241  AC123 HCT 116 C105(0.88); C100(1.05); C339(1.15); C348(1.09)  LDD0558  [14]
 LDCM0242  AC124 HCT 116 C105(1.06); C100(1.05); C339(1.08); C348(1.07)  LDD0559  [14]
 LDCM0243  AC125 HCT 116 C105(1.13); C100(1.11); C339(1.15); C348(1.16)  LDD0560  [14]
 LDCM0244  AC126 HCT 116 C105(1.07); C100(1.20); C339(1.24); C348(1.26)  LDD0561  [14]
 LDCM0245  AC127 HCT 116 C105(1.15); C100(1.19); C339(1.18); C348(1.20)  LDD0562  [14]
 LDCM0246  AC128 HCT 116 C105(1.47); C100(1.43); C339(0.93); C348(0.93)  LDD0563  [14]
 LDCM0247  AC129 HCT 116 C105(1.01); C100(1.01); C339(1.02); C348(1.02)  LDD0564  [14]
 LDCM0249  AC130 HCT 116 C105(1.30); C100(1.27); C339(1.17); C348(1.17)  LDD0566  [14]
 LDCM0250  AC131 HCT 116 C105(0.94); C100(1.00); C339(1.10); C348(1.10)  LDD0567  [14]
 LDCM0251  AC132 HCT 116 C105(1.06); C100(1.08); C339(1.00); C348(1.00)  LDD0568  [14]
 LDCM0252  AC133 HCT 116 C105(1.22); C100(1.22); C339(1.02); C348(1.02)  LDD0569  [14]
 LDCM0253  AC134 HCT 116 C105(1.31); C100(1.33); C339(1.08); C348(1.08)  LDD0570  [14]
 LDCM0254  AC135 HCT 116 C105(1.32); C100(1.36); C339(1.07); C348(1.07)  LDD0571  [14]
 LDCM0255  AC136 HCT 116 C105(1.32); C100(1.34); C339(0.93); C348(0.93)  LDD0572  [14]
 LDCM0256  AC137 HCT 116 C105(1.17); C100(1.18); C339(0.92); C348(0.92)  LDD0573  [14]
 LDCM0257  AC138 HCT 116 C105(1.38); C100(1.45); C339(0.87); C348(0.87)  LDD0574  [14]
 LDCM0258  AC139 HCT 116 C105(1.39); C100(1.40); C339(0.99); C348(0.99)  LDD0575  [14]
 LDCM0259  AC14 HCT 116 C105(1.45); C100(1.32); C339(1.13); C348(1.06)  LDD0576  [14]
 LDCM0260  AC140 HCT 116 C105(1.44); C100(1.43); C339(1.05); C348(1.05)  LDD0577  [14]
 LDCM0261  AC141 HCT 116 C105(1.39); C100(1.40); C339(0.92); C348(0.92)  LDD0578  [14]
 LDCM0262  AC142 HCT 116 C105(1.33); C100(1.26); C339(0.82); C348(0.82)  LDD0579  [14]
 LDCM0263  AC143 HCT 116 C105(1.20); C100(1.20); C339(1.01); C348(1.01)  LDD0580  [14]
 LDCM0264  AC144 HCT 116 C426(0.93); C496(0.98); C339(1.24); C348(1.25)  LDD0581  [14]
 LDCM0265  AC145 HCT 116 C426(0.87); C339(0.99); C348(1.05); C100(1.26)  LDD0582  [14]
 LDCM0266  AC146 HCT 116 C426(0.82); C496(1.04); C339(1.09); C348(1.20)  LDD0583  [14]
 LDCM0267  AC147 HCT 116 C426(0.86); C496(0.99); C339(1.32); C105(1.34)  LDD0584  [14]
 LDCM0268  AC148 HCT 116 C426(0.76); C496(1.02); C339(1.46); C348(1.54)  LDD0585  [14]
 LDCM0269  AC149 HCT 116 C496(0.72); C426(0.80); C339(1.16); C348(1.29)  LDD0586  [14]
 LDCM0270  AC15 HCT 116 C426(1.04); C496(1.12); C339(1.14); C348(1.18)  LDD0587  [14]
 LDCM0271  AC150 HCT 116 C496(0.82); C426(0.96); C339(0.99); C348(1.03)  LDD0588  [14]
 LDCM0272  AC151 HCT 116 C426(0.95); C496(0.98); C348(0.99); C339(0.99)  LDD0589  [14]
 LDCM0273  AC152 HCT 116 C426(0.98); C339(1.23); C348(1.26); C496(1.31)  LDD0590  [14]
 LDCM0274  AC153 HCT 116 C426(0.82); C496(0.91); C339(1.34); C348(1.41)  LDD0591  [14]
 LDCM0621  AC154 HCT 116 C105(1.29); C100(1.27); C339(1.15); C348(1.19)  LDD2158  [14]
 LDCM0622  AC155 HCT 116 C105(1.33); C100(1.29); C339(1.13); C348(1.18)  LDD2159  [14]
 LDCM0623  AC156 HCT 116 C105(1.05); C100(1.03); C339(1.00); C348(1.11)  LDD2160  [14]
 LDCM0624  AC157 HCT 116 C105(1.04); C100(1.02); C339(0.98); C348(0.98)  LDD2161  [14]
 LDCM0276  AC17 HCT 116 C503(0.65); C506(0.65); C339(0.77); C348(0.77)  LDD0593  [14]
 LDCM0277  AC18 HCT 116 C339(0.82); C348(0.82); C503(0.96); C506(0.96)  LDD0594  [14]
 LDCM0278  AC19 HCT 116 C503(0.67); C506(0.67); C339(0.80); C348(0.80)  LDD0595  [14]
 LDCM0279  AC2 HCT 116 C339(0.85); C348(0.85); C426(1.13); C105(1.26)  LDD0596  [14]
 LDCM0280  AC20 HCT 116 C339(0.78); C348(0.78); C503(0.82); C506(0.82)  LDD0597  [14]
 LDCM0281  AC21 HCT 116 C503(0.64); C506(0.64); C339(0.75); C348(0.75)  LDD0598  [14]
 LDCM0282  AC22 HCT 116 C503(0.58); C506(0.58); C339(0.73); C348(0.73)  LDD0599  [14]
 LDCM0283  AC23 HCT 116 C503(0.58); C506(0.58); C339(0.65); C348(0.65)  LDD0600  [14]
 LDCM0284  AC24 HCT 116 C339(0.63); C348(0.63); C503(0.69); C506(0.69)  LDD0601  [14]
 LDCM0285  AC25 HCT 116 C426(0.94); C496(0.94); C100(1.05); C105(1.13)  LDD0602  [14]
 LDCM0286  AC26 HCT 116 C496(0.95); C426(0.99); C348(1.26); C339(1.27)  LDD0603  [14]
 LDCM0287  AC27 HCT 116 C426(0.91); C100(1.07); C496(1.09); C105(1.15)  LDD0604  [14]
 LDCM0288  AC28 HCT 116 C426(0.80); C105(1.05); C100(1.06); C496(1.07)  LDD0605  [14]
 LDCM0289  AC29 HCT 116 C496(1.02); C426(1.03); C100(1.15); C105(1.24)  LDD0606  [14]
 LDCM0290  AC3 HCT 116 C339(0.88); C348(0.88); C496(1.10); C105(1.23)  LDD0607  [14]
 LDCM0291  AC30 HCT 116 C426(1.00); C496(1.10); C339(1.23); C100(1.23)  LDD0608  [14]
 LDCM0292  AC31 HCT 116 C426(0.93); C496(1.13); C100(1.19); C105(1.30)  LDD0609  [14]
 LDCM0293  AC32 HCT 116 C426(1.01); C496(1.21); C339(1.34); C348(1.34)  LDD0610  [14]
 LDCM0294  AC33 HCT 116 C426(0.93); C496(1.18); C100(1.20); C105(1.32)  LDD0611  [14]
 LDCM0295  AC34 HCT 116 C426(0.99); C105(1.29); C496(1.29); C100(1.30)  LDD0612  [14]
 LDCM0296  AC35 HCT 116 C105(0.85); C496(0.87); C100(0.91); C348(0.93)  LDD0613  [14]
 LDCM0297  AC36 HCT 116 C105(0.86); C496(0.88); C100(0.91); C348(0.96)  LDD0614  [14]
 LDCM0298  AC37 HCT 116 C496(0.85); C348(0.95); C105(0.96); C100(1.00)  LDD0615  [14]
 LDCM0299  AC38 HCT 116 C496(0.93); C105(0.94); C100(0.95); C339(1.00)  LDD0616  [14]
 LDCM0300  AC39 HCT 116 C426(0.91); C105(0.95); C348(0.97); C339(1.03)  LDD0617  [14]
 LDCM0301  AC4 HCT 116 C339(0.90); C348(0.90); C496(1.12); C426(1.34)  LDD0618  [14]
 LDCM0302  AC40 HCT 116 C105(1.05); C348(1.05); C496(1.07); C426(1.08)  LDD0619  [14]
 LDCM0303  AC41 HCT 116 C496(0.97); C100(1.02); C339(1.05); C105(1.05)  LDD0620  [14]
 LDCM0304  AC42 HCT 116 C426(0.93); C339(1.03); C348(1.04); C105(1.05)  LDD0621  [14]
 LDCM0305  AC43 HCT 116 C426(1.01); C348(1.02); C105(1.03); C339(1.06)  LDD0622  [14]
 LDCM0306  AC44 HCT 116 C348(1.03); C496(1.04); C100(1.06); C426(1.06)  LDD0623  [14]
 LDCM0307  AC45 HCT 116 C348(1.01); C426(1.06); C339(1.09); C100(1.16)  LDD0624  [14]
 LDCM0308  AC46 HCT 116 C339(0.96); C348(0.96); C105(1.00); C100(1.03)  LDD0625  [14]
 LDCM0309  AC47 HCT 116 C339(0.92); C348(0.92); C426(0.98); C496(1.03)  LDD0626  [14]
 LDCM0310  AC48 HCT 116 C339(0.92); C348(0.92); C105(1.03); C426(1.05)  LDD0627  [14]
 LDCM0311  AC49 HCT 116 C339(1.02); C348(1.02); C496(1.11); C426(1.16)  LDD0628  [14]
 LDCM0312  AC5 HCT 116 C339(0.83); C348(0.83); C496(1.23); C426(1.34)  LDD0629  [14]
 LDCM0313  AC50 HCT 116 C496(1.07); C339(1.09); C348(1.09); C426(1.11)  LDD0630  [14]
 LDCM0314  AC51 HCT 116 C105(0.89); C100(0.94); C339(0.96); C348(0.96)  LDD0631  [14]
 LDCM0315  AC52 HCT 116 C339(0.95); C348(0.95); C426(1.04); C496(1.07)  LDD0632  [14]
 LDCM0316  AC53 HCT 116 C426(0.83); C339(0.97); C348(0.97); C105(0.98)  LDD0633  [14]
 LDCM0317  AC54 HCT 116 C339(0.95); C348(0.95); C426(1.01); C496(1.09)  LDD0634  [14]
 LDCM0318  AC55 HCT 116 C426(1.01); C339(1.07); C348(1.07); C496(1.09)  LDD0635  [14]
 LDCM0319  AC56 HCT 116 C426(1.05); C496(1.19); C339(1.21); C348(1.21)  LDD0636  [14]
 LDCM0320  AC57 HCT 116 C503(0.89); C506(0.89); C339(0.98); C348(0.98)  LDD0637  [14]
 LDCM0321  AC58 HCT 116 C339(1.12); C348(1.12); C426(1.13); C503(1.20)  LDD0638  [14]
 LDCM0322  AC59 HCT 116 C339(1.04); C348(1.04); C503(1.06); C506(1.06)  LDD0639  [14]
 LDCM0323  AC6 HCT 116 C426(1.05); C496(1.10); C348(1.11); C339(1.12)  LDD0640  [14]
 LDCM0324  AC60 HCT 116 C503(1.00); C506(1.00); C339(1.01); C348(1.01)  LDD0641  [14]
 LDCM0325  AC61 HCT 116 C503(0.79); C506(0.79); C339(0.91); C348(0.91)  LDD0642  [14]
 LDCM0326  AC62 HCT 116 C503(0.79); C506(0.79); C339(1.06); C348(1.06)  LDD0643  [14]
 LDCM0327  AC63 HCT 116 C503(0.97); C506(0.97); C426(1.00); C339(1.13)  LDD0644  [14]
 LDCM0328  AC64 HCT 116 C503(0.86); C506(0.86); C426(1.22); C339(1.23)  LDD0645  [14]
 LDCM0329  AC65 HCT 116 C503(0.97); C506(0.97); C496(1.43); C100(1.44)  LDD0646  [14]
 LDCM0330  AC66 HCT 116 C503(0.94); C506(0.94); C339(1.21); C348(1.21)  LDD0647  [14]
 LDCM0331  AC67 HCT 116 C503(1.07); C506(1.07); C496(1.36); C339(1.45)  LDD0648  [14]
 LDCM0332  AC68 HCT 116 C426(0.82); C503(1.02); C506(1.02); C100(1.12)  LDD0649  [14]
 LDCM0333  AC69 HCT 116 C426(0.78); C105(1.07); C503(1.07); C506(1.07)  LDD0650  [14]
 LDCM0334  AC7 HCT 116 C426(0.94); C496(0.97); C339(0.98); C348(1.02)  LDD0651  [14]
 LDCM0335  AC70 HCT 116 C426(0.91); C105(1.03); C100(1.11); C503(1.11)  LDD0652  [14]
 LDCM0336  AC71 HCT 116 C426(0.81); C105(0.97); C503(1.00); C506(1.00)  LDD0653  [14]
 LDCM0337  AC72 HCT 116 C426(0.90); C503(1.10); C506(1.10); C105(1.11)  LDD0654  [14]
 LDCM0338  AC73 HCT 116 C426(0.93); C503(1.29); C506(1.29); C105(1.43)  LDD0655  [14]
 LDCM0339  AC74 HCT 116 C426(0.86); C503(1.23); C506(1.23); C348(1.29)  LDD0656  [14]
 LDCM0340  AC75 HCT 116 C426(0.97); C503(1.29); C506(1.29); C348(1.37)  LDD0657  [14]
 LDCM0341  AC76 HCT 116 C426(0.80); C503(0.97); C506(0.97); C105(1.18)  LDD0658  [14]
 LDCM0342  AC77 HCT 116 C503(0.82); C506(0.82); C426(0.83); C496(1.26)  LDD0659  [14]
 LDCM0343  AC78 HCT 116 C426(0.79); C503(0.79); C506(0.79); C105(1.05)  LDD0660  [14]
 LDCM0344  AC79 HCT 116 C426(0.95); C503(1.06); C506(1.06); C105(1.09)  LDD0661  [14]
 LDCM0345  AC8 HCT 116 C339(1.01); C348(1.03); C426(1.04); C496(1.04)  LDD0662  [14]
 LDCM0346  AC80 HCT 116 C426(0.82); C503(1.13); C506(1.13); C105(1.18)  LDD0663  [14]
 LDCM0347  AC81 HCT 116 C426(0.79); C105(0.92); C339(0.99); C348(1.00)  LDD0664  [14]
 LDCM0348  AC82 HCT 116 C426(0.83); C348(1.02); C503(1.03); C506(1.03)  LDD0665  [14]
 LDCM0349  AC83 HCT 116 C100(1.23); C105(1.29); C348(1.29); C503(1.31)  LDD0666  [14]
 LDCM0350  AC84 HCT 116 C100(1.15); C105(1.16); C348(1.22); C339(1.25)  LDD0667  [14]
 LDCM0351  AC85 HCT 116 C105(1.05); C100(1.06); C348(1.12); C339(1.13)  LDD0668  [14]
 LDCM0352  AC86 HCT 116 C503(1.01); C506(1.01); C100(1.01); C105(1.06)  LDD0669  [14]
 LDCM0353  AC87 HCT 116 C100(0.94); C105(0.95); C348(0.99); C339(1.03)  LDD0670  [14]
 LDCM0354  AC88 HCT 116 C100(0.94); C105(0.99); C348(1.04); C339(1.06)  LDD0671  [14]
 LDCM0355  AC89 HCT 116 C100(1.02); C503(1.04); C506(1.04); C105(1.08)  LDD0672  [14]
 LDCM0357  AC90 HCT 116 C503(0.74); C506(0.74); C496(0.87); C426(0.95)  LDD0674  [14]
 LDCM0358  AC91 HCT 116 C503(1.17); C506(1.17); C100(1.24); C348(1.28)  LDD0675  [14]
 LDCM0359  AC92 HCT 116 C503(1.05); C506(1.05); C100(1.16); C348(1.24)  LDD0676  [14]
 LDCM0360  AC93 HCT 116 C100(0.98); C105(1.05); C348(1.07); C426(1.13)  LDD0677  [14]
 LDCM0361  AC94 HCT 116 C105(0.93); C100(0.94); C339(1.04); C348(1.12)  LDD0678  [14]
 LDCM0362  AC95 HCT 116 C105(1.04); C503(1.05); C506(1.05); C100(1.07)  LDD0679  [14]
 LDCM0363  AC96 HCT 116 C503(1.03); C506(1.03); C348(1.06); C426(1.11)  LDD0680  [14]
 LDCM0364  AC97 HCT 116 C348(1.12); C339(1.13); C100(1.18); C105(1.22)  LDD0681  [14]
 LDCM0365  AC98 HCT 116 C426(0.95); C348(0.98); C339(1.01); C496(1.04)  LDD0682  [14]
 LDCM0366  AC99 HCT 116 C496(0.87); C426(0.92); C105(0.97); C348(0.98)  LDD0683  [14]
 LDCM0520  AKOS000195272 MDA-MB-231 C207(0.75)  LDD2113  [7]
 LDCM0248  AKOS034007472 HCT 116 C105(1.13); C100(1.12); C339(1.01); C348(1.02)  LDD0565  [14]
 LDCM0356  AKOS034007680 HCT 116 C426(0.89); C339(1.02); C496(1.07); C348(1.07)  LDD0673  [14]
 LDCM0275  AKOS034007705 HCT 116 C426(1.12); C348(1.32); C339(1.50); C496(1.51)  LDD0592  [14]
 LDCM0156  Aniline NCI-H1299 11.50  LDD0403  [1]
 LDCM0020  ARS-1620 HCC44 C100(1.01); C105(1.01); C426(0.97)  LDD0078  [14]
 LDCM0630  CCW28-3 231MFP C100(1.64)  LDD2214  [29]
 LDCM0632  CL-Sc Hep-G2 C100(1.19)  LDD2227  [20]
 LDCM0367  CL1 HCT 116 C496(0.95); C426(1.06); C339(1.16); C348(1.16)  LDD0684  [14]
 LDCM0368  CL10 HCT 116 C426(0.87); C339(1.19); C348(1.19); C496(1.52)  LDD0685  [14]
 LDCM0369  CL100 HCT 116 C339(0.91); C348(0.91); C496(1.27); C426(1.39)  LDD0686  [14]
 LDCM0370  CL101 HCT 116 C426(0.99); C496(1.18); C348(1.20); C339(1.32)  LDD0687  [14]
 LDCM0371  CL102 HCT 116 C496(1.01); C426(1.09); C339(1.17); C348(1.17)  LDD0688  [14]
 LDCM0372  CL103 HCT 116 C426(0.96); C496(1.04); C348(1.31); C100(1.53)  LDD0689  [14]
 LDCM0373  CL104 HCT 116 C496(0.96); C426(0.98); C339(1.07); C348(1.07)  LDD0690  [14]
 LDCM0374  CL105 HCT 116 C503(0.62); C506(0.62); C339(0.75); C348(0.75)  LDD0691  [14]
 LDCM0375  CL106 HCT 116 C503(0.57); C506(0.57); C339(0.72); C348(0.72)  LDD0692  [14]
 LDCM0376  CL107 HCT 116 C503(0.66); C506(0.66); C339(0.90); C348(0.90)  LDD0693  [14]
 LDCM0377  CL108 HCT 116 C503(0.56); C506(0.56); C339(0.68); C348(0.68)  LDD0694  [14]
 LDCM0378  CL109 HCT 116 C503(0.57); C506(0.57); C339(0.87); C348(0.87)  LDD0695  [14]
 LDCM0379  CL11 HCT 116 C426(0.88); C339(1.08); C348(1.08); C496(1.46)  LDD0696  [14]
 LDCM0380  CL110 HCT 116 C503(0.45); C506(0.45); C339(0.68); C348(0.68)  LDD0697  [14]
 LDCM0381  CL111 HCT 116 C503(0.64); C506(0.64); C339(0.84); C348(0.84)  LDD0698  [14]
 LDCM0382  CL112 HCT 116 C426(0.84); C496(1.00); C105(1.06); C339(1.10)  LDD0699  [14]
 LDCM0383  CL113 HCT 116 C426(1.01); C496(1.16); C105(1.26); C339(1.26)  LDD0700  [14]
 LDCM0384  CL114 HCT 116 C496(1.06); C426(1.34); C339(1.43); C100(1.47)  LDD0701  [14]
 LDCM0385  CL115 HCT 116 C426(0.89); C339(1.14); C348(1.17); C496(1.19)  LDD0702  [14]
 LDCM0386  CL116 HCT 116 C426(0.96); C496(1.04); C100(1.17); C348(1.24)  LDD0703  [14]
 LDCM0387  CL117 HCT 116 C426(0.97); C348(1.05); C339(1.13); C496(1.48)  LDD0704  [14]
 LDCM0388  CL118 HCT 116 C348(0.89); C339(0.90); C496(1.04); C105(1.10)  LDD0705  [14]
 LDCM0389  CL119 HCT 116 C348(0.96); C339(0.98); C426(1.07); C496(1.09)  LDD0706  [14]
 LDCM0390  CL12 HCT 116 C426(0.97); C339(1.04); C348(1.04); C100(1.45)  LDD0707  [14]
 LDCM0391  CL120 HCT 116 C348(0.88); C339(0.95); C496(0.98); C105(1.05)  LDD0708  [14]
 LDCM0392  CL121 HCT 116 C426(0.98); C496(1.11); C339(1.36); C348(1.36)  LDD0709  [14]
 LDCM0393  CL122 HCT 116 C339(0.84); C348(0.84); C426(0.96); C496(1.18)  LDD0710  [14]
 LDCM0394  CL123 HCT 116 C426(1.08); C496(1.08); C339(1.70); C348(1.70)  LDD0711  [14]
 LDCM0395  CL124 HCT 116 C426(1.09); C339(1.11); C348(1.11); C496(1.27)  LDD0712  [14]
 LDCM0396  CL125 HCT 116 C503(0.86); C506(0.86); C339(0.87); C348(0.87)  LDD0713  [14]
 LDCM0397  CL126 HCT 116 C503(0.94); C506(0.94); C426(1.08); C496(1.22)  LDD0714  [14]
 LDCM0398  CL127 HCT 116 C339(0.86); C348(0.86); C503(0.97); C506(0.97)  LDD0715  [14]
 LDCM0399  CL128 HCT 116 C503(0.86); C506(0.86); C339(1.04); C348(1.04)  LDD0716  [14]
 LDCM0400  CL13 HCT 116 C339(0.87); C348(0.87); C426(0.92); C496(1.31)  LDD0717  [14]
 LDCM0401  CL14 HCT 116 C426(0.98); C496(1.07); C339(1.27); C348(1.27)  LDD0718  [14]
 LDCM0402  CL15 HCT 116 C426(1.11); C339(1.23); C348(1.23); C496(1.30)  LDD0719  [14]
 LDCM0403  CL16 HCT 116 C426(0.94); C503(0.94); C506(0.94); C339(1.00)  LDD0720  [14]
 LDCM0404  CL17 HCT 116 C503(0.88); C506(0.88); C496(1.10); C426(1.18)  LDD0721  [14]
 LDCM0405  CL18 HCT 116 C503(0.81); C506(0.81); C348(0.94); C426(1.05)  LDD0722  [14]
 LDCM0406  CL19 HCT 116 C503(0.83); C506(0.83); C348(0.91); C426(0.94)  LDD0723  [14]
 LDCM0407  CL2 HCT 116 C339(0.90); C348(0.90); C105(0.96); C426(0.97)  LDD0724  [14]
 LDCM0408  CL20 HCT 116 C503(0.73); C506(0.73); C348(0.96); C339(0.98)  LDD0725  [14]
 LDCM0409  CL21 HCT 116 C503(0.81); C506(0.81); C426(1.18); C348(1.34)  LDD0726  [14]
 LDCM0410  CL22 HCT 116 C503(1.01); C506(1.01); C348(1.22); C339(1.24)  LDD0727  [14]
 LDCM0411  CL23 HCT 116 C503(0.91); C506(0.91); C100(1.10); C426(1.12)  LDD0728  [14]
 LDCM0412  CL24 HCT 116 C503(0.89); C506(0.89); C426(1.12); C348(1.14)  LDD0729  [14]
 LDCM0413  CL25 HCT 116 C105(2.35); C100(1.81); C339(1.18); C348(1.12)  LDD0730  [14]
 LDCM0414  CL26 HCT 116 C105(1.29); C100(1.12); C339(1.20); C348(1.08)  LDD0731  [14]
 LDCM0415  CL27 HCT 116 C105(1.36); C100(1.10); C339(0.97); C348(0.94)  LDD0732  [14]
 LDCM0416  CL28 HCT 116 C105(2.08); C100(1.69); C339(1.07); C348(1.00)  LDD0733  [14]
 LDCM0417  CL29 HCT 116 C105(1.56); C100(1.33); C339(0.99); C348(0.95)  LDD0734  [14]
 LDCM0418  CL3 HCT 116 C105(1.10); C100(1.12); C339(0.94); C348(0.94)  LDD0735  [14]
 LDCM0419  CL30 HCT 116 C105(1.26); C100(1.13); C339(0.99); C348(0.91)  LDD0736  [14]
 LDCM0420  CL31 HCT 116 C105(1.43); C100(1.48); C339(1.08); C348(1.03)  LDD0737  [14]
 LDCM0421  CL32 HCT 116 C105(1.23); C100(1.25); C339(0.97); C348(0.97)  LDD0738  [14]
 LDCM0422  CL33 HCT 116 C105(2.41); C100(2.40); C339(2.23); C348(2.23)  LDD0739  [14]
 LDCM0423  CL34 HCT 116 C105(1.63); C100(1.69); C339(1.09); C348(1.09)  LDD0740  [14]
 LDCM0424  CL35 HCT 116 C105(1.24); C100(1.31); C339(1.12); C348(1.12)  LDD0741  [14]
 LDCM0425  CL36 HCT 116 C105(1.71); C100(1.81); C339(1.11); C348(1.11)  LDD0742  [14]
 LDCM0426  CL37 HCT 116 C105(1.36); C100(1.40); C339(1.20); C348(1.20)  LDD0743  [14]
 LDCM0428  CL39 HCT 116 C105(1.62); C100(1.69); C339(1.14); C348(1.14)  LDD0745  [14]
 LDCM0429  CL4 HCT 116 C105(1.20); C100(1.28); C339(1.02); C348(1.02)  LDD0746  [14]
 LDCM0430  CL40 HCT 116 C105(1.71); C100(1.70); C339(1.09); C348(1.09)  LDD0747  [14]
 LDCM0431  CL41 HCT 116 C105(1.33); C100(1.44); C339(1.24); C348(1.24)  LDD0748  [14]
 LDCM0432  CL42 HCT 116 C105(2.08); C100(2.36); C339(1.33); C348(1.33)  LDD0749  [14]
 LDCM0433  CL43 HCT 116 C105(1.31); C100(1.40); C339(1.22); C348(1.22)  LDD0750  [14]
 LDCM0434  CL44 HCT 116 C105(1.37); C100(1.48); C339(1.04); C348(1.04)  LDD0751  [14]
 LDCM0435  CL45 HCT 116 C105(1.75); C100(1.76); C339(1.10); C348(1.10)  LDD0752  [14]
 LDCM0436  CL46 HCT 116 C105(1.30); C100(1.17); C339(0.96); C348(0.95)  LDD0753  [14]
 LDCM0437  CL47 HCT 116 C105(0.99); C100(0.98); C339(0.88); C348(0.89)  LDD0754  [14]
 LDCM0438  CL48 HCT 116 C105(1.00); C100(1.02); C339(1.10); C348(1.11)  LDD0755  [14]
 LDCM0439  CL49 HCT 116 C105(1.04); C100(1.05); C339(1.03); C348(1.04)  LDD0756  [14]
 LDCM0440  CL5 HCT 116 C105(0.99); C100(1.00); C339(0.98); C348(0.98)  LDD0757  [14]
 LDCM0441  CL50 HCT 116 C105(0.93); C100(0.98); C339(0.99); C348(0.98)  LDD0758  [14]
 LDCM0442  CL51 HCT 116 C105(1.02); C100(1.01); C339(1.04); C348(1.02)  LDD0759  [14]
 LDCM0443  CL52 HCT 116 C105(1.08); C100(1.01); C339(1.09); C348(1.07)  LDD0760  [14]
 LDCM0444  CL53 HCT 116 C105(1.05); C100(1.08); C339(1.15); C348(1.09)  LDD0761  [14]
 LDCM0445  CL54 HCT 116 C105(1.07); C100(1.01); C339(1.19); C348(1.16)  LDD0762  [14]
 LDCM0446  CL55 HCT 116 C105(0.99); C100(0.91); C339(1.16); C348(1.14)  LDD0763  [14]
 LDCM0447  CL56 HCT 116 C105(1.07); C100(1.03); C339(0.97); C348(0.97)  LDD0764  [14]
 LDCM0448  CL57 HCT 116 C105(1.23); C100(1.13); C339(1.17); C348(1.16)  LDD0765  [14]
 LDCM0449  CL58 HCT 116 C105(0.94); C100(0.92); C339(1.11); C348(1.12)  LDD0766  [14]
 LDCM0450  CL59 HCT 116 C105(0.87); C100(0.87); C339(1.14); C348(1.14)  LDD0767  [14]
 LDCM0451  CL6 HCT 116 C105(1.08); C100(1.13); C339(1.10); C348(1.10)  LDD0768  [14]
 LDCM0452  CL60 HCT 116 C105(0.98); C100(1.03); C339(1.05); C348(1.05)  LDD0769  [14]
 LDCM0453  CL61 HCT 116 C105(1.02); C100(1.08); C339(1.05); C348(1.07)  LDD0770  [14]
 LDCM0454  CL62 HCT 116 C105(1.00); C100(0.99); C339(0.99); C348(1.05)  LDD0771  [14]
 LDCM0455  CL63 HCT 116 C105(1.22); C100(1.24); C339(1.06); C348(1.14)  LDD0772  [14]
 LDCM0456  CL64 HCT 116 C105(1.51); C100(1.43); C339(1.14); C348(1.21)  LDD0773  [14]
 LDCM0457  CL65 HCT 116 C105(1.01); C100(1.01); C339(0.93); C348(0.96)  LDD0774  [14]
 LDCM0458  CL66 HCT 116 C105(1.71); C100(1.55); C339(0.98); C348(1.03)  LDD0775  [14]
 LDCM0459  CL67 HCT 116 C105(1.06); C100(1.09); C339(0.97); C348(1.04)  LDD0776  [14]
 LDCM0460  CL68 HCT 116 C105(1.33); C100(1.33); C339(1.14); C348(1.20)  LDD0777  [14]
 LDCM0461  CL69 HCT 116 C105(1.46); C100(1.44); C339(1.01); C348(1.08)  LDD0778  [14]
 LDCM0462  CL7 HCT 116 C105(1.15); C100(1.14); C339(1.03); C348(1.03)  LDD0779  [14]
 LDCM0463  CL70 HCT 116 C105(1.08); C100(1.08); C339(1.08); C348(1.12)  LDD0780  [14]
 LDCM0464  CL71 HCT 116 C105(1.24); C100(1.25); C339(1.00); C348(1.04)  LDD0781  [14]
 LDCM0465  CL72 HCT 116 C105(1.05); C100(1.04); C339(0.90); C348(0.96)  LDD0782  [14]
 LDCM0466  CL73 HCT 116 C105(1.45); C100(1.50); C339(1.05); C348(1.09)  LDD0783  [14]
 LDCM0467  CL74 HCT 116 C105(1.18); C100(1.19); C339(1.00); C348(1.08)  LDD0784  [14]
 LDCM0469  CL76 HCT 116 C105(1.25); C100(1.27); C339(0.86); C348(0.86)  LDD0786  [14]
 LDCM0470  CL77 HCT 116 C105(2.45); C100(2.64); C339(1.00); C348(1.00)  LDD0787  [14]
 LDCM0471  CL78 HCT 116 C105(1.57); C100(1.56); C339(0.93); C348(0.93)  LDD0788  [14]
 LDCM0472  CL79 HCT 116 C105(1.38); C100(1.41); C339(1.00); C348(1.00)  LDD0789  [14]
 LDCM0473  CL8 HCT 116 C105(4.03); C100(3.54); C339(1.79); C348(1.79)  LDD0790  [14]
 LDCM0474  CL80 HCT 116 C105(1.09); C100(1.18); C339(0.85); C348(0.85)  LDD0791  [14]
 LDCM0475  CL81 HCT 116 C105(1.20); C100(1.23); C339(0.92); C348(0.92)  LDD0792  [14]
 LDCM0476  CL82 HCT 116 C105(1.45); C100(1.45); C339(1.12); C348(1.12)  LDD0793  [14]
 LDCM0477  CL83 HCT 116 C105(1.68); C100(1.79); C339(0.89); C348(0.89)  LDD0794  [14]
 LDCM0478  CL84 HCT 116 C105(2.27); C100(2.21); C339(0.95); C348(0.95)  LDD0795  [14]
 LDCM0479  CL85 HCT 116 C105(1.31); C100(1.32); C339(0.87); C348(0.87)  LDD0796  [14]
 LDCM0480  CL86 HCT 116 C105(1.48); C100(1.45); C339(0.82); C348(0.82)  LDD0797  [14]
 LDCM0481  CL87 HCT 116 C105(2.85); C100(3.04); C339(0.91); C348(0.91)  LDD0798  [14]
 LDCM0482  CL88 HCT 116 C105(1.49); C100(1.49); C339(0.98); C348(0.98)  LDD0799  [14]
 LDCM0483  CL89 HCT 116 C105(2.15); C100(2.13); C339(0.87); C348(0.87)  LDD0800  [14]
 LDCM0484  CL9 HCT 116 C105(1.14); C100(1.15); C339(0.92); C348(0.92)  LDD0801  [14]
 LDCM0485  CL90 HCT 116 C105(6.11); C100(7.45); C339(1.24); C348(1.24)  LDD0802  [14]
 LDCM0486  CL91 HCT 116 C105(1.20); C100(1.21); C339(0.99); C348(0.99)  LDD0803  [14]
 LDCM0487  CL92 HCT 116 C105(2.07); C100(1.94); C339(1.16); C348(1.16)  LDD0804  [14]
 LDCM0488  CL93 HCT 116 C105(1.25); C100(1.28); C339(0.98); C348(0.98)  LDD0805  [14]
 LDCM0489  CL94 HCT 116 C105(1.57); C100(1.59); C339(1.31); C348(1.31)  LDD0806  [14]
 LDCM0490  CL95 HCT 116 C105(1.84); C100(1.79); C339(1.79); C348(1.79)  LDD0807  [14]
 LDCM0491  CL96 HCT 116 C105(1.76); C100(1.64); C339(1.05); C348(1.05)  LDD0808  [14]
 LDCM0492  CL97 HCT 116 C105(1.63); C100(1.59); C339(0.95); C348(0.95)  LDD0809  [14]
 LDCM0493  CL98 HCT 116 C105(1.52); C100(1.56); C339(0.92); C348(0.92)  LDD0810  [14]
 LDCM0494  CL99 HCT 116 C105(1.69); C100(1.60); C339(0.81); C348(0.81)  LDD0811  [14]
 LDCM0097  Dasatinib K562 6.00  LDD0270  [6]
 LDCM0495  E2913 HEK-293T C207(0.90); C496(0.94); C426(1.13); C100(1.05)  LDD1698  [30]
 LDCM0031  Epigallocatechin gallate HEK-293T 9.83  LDD0183  [8]
 LDCM0175  Ethacrynic acid HeLa N.A.  LDD0440  [10]
 LDCM0625  F8 Ramos 1.15; C496(5.31)  LDD2187  [31]
 LDCM0572  Fragment10 Ramos C100(20.00)  LDD1466  [32]
 LDCM0573  Fragment11 Ramos C496(0.19)  LDD2190  [31]
 LDCM0574  Fragment12 Ramos 1.61; C496(0.34)  LDD2191  [31]
 LDCM0575  Fragment13 Ramos C100(1.96)  LDD1470  [32]
 LDCM0576  Fragment14 Ramos 0.95; C496(0.89)  LDD2193  [31]
 LDCM0579  Fragment20 Ramos C496(0.70)  LDD2194  [31]
 LDCM0580  Fragment21 Ramos 0.96; C496(0.28)  LDD2195  [31]
 LDCM0582  Fragment23 Ramos 0.76; C496(0.64)  LDD2196  [31]
 LDCM0578  Fragment27 MDA-MB-231 C100(0.77)  LDD1474  [32]
 LDCM0586  Fragment28 Ramos 1.29; C496(0.45)  LDD2198  [31]
 LDCM0587  Fragment29 Ramos C100(1.58)  LDD1476  [32]
 LDCM0588  Fragment30 Ramos 0.70; C496(0.82)  LDD2199  [31]
 LDCM0589  Fragment31 MDA-MB-231 C100(0.57)  LDD1477  [32]
 LDCM0468  Fragment33 HCT 116 C105(1.27); C100(1.31); C339(0.97); C348(1.06)  LDD0785  [14]
 LDCM0596  Fragment38 MDA-MB-231 C100(1.16)  LDD1480  [32]
 LDCM0566  Fragment4 MDA-MB-231 C100(1.72)  LDD1461  [32]
 LDCM0427  Fragment51 HCT 116 C105(2.67); C100(2.44); C339(1.20); C348(1.20)  LDD0744  [14]
 LDCM0610  Fragment52 Ramos 0.92  LDD2204  [31]
 LDCM0614  Fragment56 Ramos 1.00; C496(0.58)  LDD2205  [31]
 LDCM0569  Fragment7 Ramos 1.35; C496(1.16)  LDD2186  [31]
 LDCM0571  Fragment9 Ramos C100(2.89)  LDD1464  [32]
 LDCM0118  HHS-0301 DM93 Y246(1.05); Y451(10.76)  LDD0266  [12]
 LDCM0120  HHS-0701 DM93 Y246(4.53)  LDD0268  [12]
 LDCM0123  JWB131 DM93 Y94(0.94)  LDD0285  [11]
 LDCM0124  JWB142 DM93 Y94(0.57)  LDD0286  [11]
 LDCM0125  JWB146 DM93 Y94(1.17)  LDD0287  [11]
 LDCM0126  JWB150 DM93 Y94(2.03)  LDD0288  [11]
 LDCM0127  JWB152 DM93 Y94(1.64)  LDD0289  [11]
 LDCM0128  JWB198 DM93 Y94(1.23)  LDD0290  [11]
 LDCM0129  JWB202 DM93 Y94(0.29)  LDD0291  [11]
 LDCM0130  JWB211 DM93 Y94(0.94)  LDD0292  [11]
 LDCM0022  KB02 HCT 116 C339(4.55); C348(4.55); C100(4.25); C105(4.25)  LDD0080  [14]
 LDCM0023  KB03 HCT 116 C339(7.68); C348(7.68); C100(11.26); C105(11.26)  LDD0081  [14]
 LDCM0024  KB05 HCT 116 C339(6.12); C348(6.12); C100(5.02); C105(5.02)  LDD0082  [14]
 LDCM0508  Nucleophilic fragment 17a MDA-MB-231 C207(0.85)  LDD2101  [7]
 LDCM0514  Nucleophilic fragment 20a MDA-MB-231 C207(1.01)  LDD2107  [7]
 LDCM0516  Nucleophilic fragment 21a MDA-MB-231 C207(1.18)  LDD2109  [7]
 LDCM0522  Nucleophilic fragment 24a MDA-MB-231 C207(0.55)  LDD2115  [7]
 LDCM0523  Nucleophilic fragment 24b MDA-MB-231 C100(0.90)  LDD2116  [7]
 LDCM0526  Nucleophilic fragment 26a MDA-MB-231 C207(6.19); C503(1.58)  LDD2119  [7]
 LDCM0527  Nucleophilic fragment 26b MDA-MB-231 C506(0.56)  LDD2120  [7]
 LDCM0530  Nucleophilic fragment 28a MDA-MB-231 C207(0.90); C503(0.89)  LDD2123  [7]
 LDCM0533  Nucleophilic fragment 29b MDA-MB-231 C100(1.47)  LDD2126  [7]
 LDCM0534  Nucleophilic fragment 30a MDA-MB-231 C207(1.00); C506(1.16); C503(0.74)  LDD2127  [7]
 LDCM0536  Nucleophilic fragment 31 MDA-MB-231 C207(1.10)  LDD2129  [7]
 LDCM0541  Nucleophilic fragment 36 MDA-MB-231 C207(0.64)  LDD2134  [7]
 LDCM0542  Nucleophilic fragment 37 MDA-MB-231 C207(1.12)  LDD2135  [7]
 LDCM0543  Nucleophilic fragment 38 MDA-MB-231 C207(0.78)  LDD2136  [7]
 LDCM0546  Nucleophilic fragment 40 MDA-MB-231 C503(1.17)  LDD2140  [7]
 LDCM0549  Nucleophilic fragment 43 MDA-MB-231 C503(0.82)  LDD2143  [7]
 LDCM0550  Nucleophilic fragment 5a MDA-MB-231 C207(2.38)  LDD2144  [7]
 LDCM0552  Nucleophilic fragment 6a MDA-MB-231 C503(1.05)  LDD2146  [7]
 LDCM0553  Nucleophilic fragment 6b MDA-MB-231 C503(1.31)  LDD2147  [7]
 LDCM0554  Nucleophilic fragment 7a MDA-MB-231 C207(0.50)  LDD2148  [7]
 LDCM0627  NUDT7-COV-1 HEK-293T C105(0.64); C105(0.23)  LDD2206  [33]
 LDCM0628  OTUB2-COV-1 HEK-293T C100(1.00); C496(0.48); C100(0.30)  LDD2207  [33]
 LDCM0131  RA190 MM1.R C100(1.07)  LDD0304  [34]
 LDCM0170  Structure8 Ramos 14.01  LDD0433  [35]
 LDCM0021  THZ1 HCT 116 C426(1.09); C503(1.22); C506(1.22); C100(1.15)  LDD2173  [14]

The Interaction Atlas With This Target

The Drug(s) Related To This Target

Approved
Click To Hide/Show 5 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
Azathioprine Small molecular drug D07QCE
Dasatinib Small molecular drug DB01254
Fluorouracil Small molecular drug DB00544
L-glutamine Small molecular drug DB00130
Mercaptopurine Small molecular drug D09UZO
Investigative
Click To Hide/Show 4 Drug(s) Interacting with This Target
Drug Name Drug Type External ID
6-chloropurine Riboside, 5'-monophosphate Small molecular drug D0VD5N
Mycophenolic Bis(Sulfonamide) Small molecular drug D0T4UE
Mycophenolic Hydroxamic Acid Small molecular drug D01LDQ
Tiazofurin Adenine Dinucleotide Small molecular drug D0S4BK

References

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Mass spectrometry data entry: PXD028270
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Mass spectrometry data entry: PXD039908 , PXD029761
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Mass spectrometry data entry: PXD043348
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Mass spectrometry data entry: PXD044625
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Mass spectrometry data entry: PXD042377
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Mass spectrometry data entry: PXD028853
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Mass spectrometry data entry: PXD023056 , PXD023059 , PXD023058 , PXD023057 , PXD023060
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Mass spectrometry data entry: PXD029500 , PXD031647
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Mass spectrometry data entry: PXD041264
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Mass spectrometry data entry: PXD027758 , PXD027755 , PXD027760 , PXD027762 , PXD027756 , PXD027591 , PXD007149 , PXD030064 , PXD032392 , PXD027789 , PXD027767 , PXD027764
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Mass spectrometry data entry: PXD022279
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Mass spectrometry data entry: PXD033004
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Mass spectrometry data entry: PXD041587
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Mass spectrometry data entry: PXD007570
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Mass spectrometry data entry: PXD044402
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Mass spectrometry data entry: PXD027578
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