Details of the Competitor

General Information of Competitor

Competitor ID
LDCM0129
Competitor Name
JWB202
Synonyms
SCHEMBL22558338
Structure
3D MOL 2D MOL
Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 362.4
Lipid-water partition coefficient (xlogp) 3.5
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C19H14N4O2S
IUPAC Name
4-[1-(4-phenylphenyl)sulfonyl-1,2,4-triazol-3-yl]pyridine
Canonical SMILES
C1=CC=C(C=C1)C2=CC=C(C=C2)S(=O)(=O)N3C=NC(=N3)C4=CC=NC=C4
InChI
InChI=1S/C19H14N4O2S/c24-26(25,23-14-21-19(22-23)17-10-12-20-13-11-17)18-8-6-16(7-9-18)15-4-2-1-3-5-15/h1-14H
InChIKey
WWLDAFWXWUTFJW-UHFFFAOYSA-N

The Competitor Interaction Atlas

Probe(s) Related This Competitor

ABPP Probe
Click To Hide/Show 1 Probe Related to This Competitor
Probe Name Structure Concentration Cell-system Ref
HHS-482
 Probe Info  		50 uM Human melanoma cell lysate (DM93) [1]

Target(s) List of this Competitor

290 Enzyme Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
(3R)-3-hydroxyacyl-CoA dehydrogenase (HSD17B8) LDTP09770 0.82  LDD0291 
1,4-alpha-glucan-branching enzyme (GBE1) LDTP05419 0.37  LDD0291 
14 kDa phosphohistidine phosphatase (PHPT1) LDTP12543 0.39; 0.83  LDD0291 
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) LDTP02356 1.03  LDD0291 
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) LDTP13667 0.58  LDD0291 
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) LDTP05782 0.36  LDD0291 
26S proteasome non-ATPase regulatory subunit 3 (PSMD3) LDTP00714 1.07  LDD0291 
26S proteasome regulatory subunit 10B (PSMC6) LDTP04987 0.54  LDD0291 
26S proteasome regulatory subunit 4 (PSMC1) LDTP04962 0.53  LDD0291 
26S proteasome regulatory subunit 6B (PSMC4) LDTP04061 5.67; 3.00  LDD0291 
26S proteasome regulatory subunit 7 (PSMC2) LDTP03797 0.10  LDD0291 
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10) LDTP10954 0.49  LDD0291 
5'-3' exonuclease PLD3 (PLD3) LDTP08476 6.83  LDD0291 
5'-3' exoribonuclease 2 (XRN2) LDTP11701 0.75  LDD0291 
6-phosphogluconate dehydrogenase, decarboxylating (PGD) LDTP04499 0.40  LDD0291 
60 kDa heat shock protein, mitochondrial (HSPD1) LDTP02522 0.15; 0.55; 0.42 ...  LDD0291 
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) LDTP11321 0.77  LDD0291 
Acetyl-CoA acetyltransferase, mitochondrial (ACAT1) LDTP03291 0.79  LDD0291 
Acetyl-CoA carboxylase 1 (ACACA) LDTP05742 0.92  LDD0291 
Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) LDTP12463 0.20  LDD0291 
Actin, alpha cardiac muscle 1 (ACTC1) LDTP05069 0.45  LDD0291 
Actin, cytoplasmic 1 (ACTB) LDTP04876 0.38; 0.63; 0.55 ...  LDD0291 
Acylamino-acid-releasing enzyme (APEH) LDTP02693 0.09  LDD0291 
Adenosylhomocysteinase (AHCY) LDTP03242 0.41; 0.37  LDD0291 
Adenylosuccinate synthetase isozyme 2 (ADSS2) LDTP03541 10.03  LDD0291 
ADP-ribose pyrophosphatase, mitochondrial (NUDT9) LDTP11318 0.36  LDD0291 
ADP-ribosylation factor 1 (ARF1) LDTP05192 1.07; 0.74  LDD0291 
ADP-ribosylation factor 3 (ARF3) LDTP04907 1.07; 0.74  LDD0291 
ADP-ribosylation factor 4 (ARF4) LDTP02942 1.07; 0.74  LDD0291 
ADP-ribosylation factor 5 (ARF5) LDTP05193 1.07; 0.74  LDD0291 
ADP-sugar pyrophosphatase (NUDT5) LDTP13462 0.74  LDD0291 
Aflatoxin B1 aldehyde reductase member 2 (AKR7A2) LDTP00776 0.32; 0.82; 0.95 ...  LDD0291 
Alanine--tRNA ligase, cytoplasmic (AARS1) LDTP04262 0.73; 0.44  LDD0291 
Alcohol dehydrogenase class-3 (ADH5) LDTP02587 2.18; 0.62; 0.50  LDD0291 
Aldo-keto reductase family 1 member A1 (AKR1A1) LDTP02729 0.44  LDD0291 
Alpha-aminoadipic semialdehyde synthase, mitochondrial (AASS) LDTP13186 0.30; 0.07; 1.51  LDD0291 
Alpha-enolase (ENO1) LDTP02159 0.63; 0.44; 2.18 ...  LDD0291 
Amidophosphoribosyltransferase (PPAT) LDTP05480 0.29  LDD0291 
Arginine--tRNA ligase, cytoplasmic (RARS1) LDTP04601 0.05; 0.76  LDD0291 
Asparagine synthetase [glutamine-hydrolyzing] (ASNS) LDTP02264 0.41  LDD0291 
Asparagine--tRNA ligase, cytoplasmic (NARS1) LDTP00866 0.58; 0.56; 0.24 ...  LDD0291 
Aspartate--tRNA ligase, cytoplasmic (DARS1) LDTP02752 6.39; 0.38; 0.23  LDD0291 
ATP synthase subunit beta, mitochondrial (ATP5F1B) LDTP02150 1.93; 0.76; 0.93  LDD0291 
ATP-binding cassette sub-family E member 1 (ABCE1) LDTP04909 0.48; 1.56; 0.29  LDD0291 
ATP-citrate synthase (ACLY) LDTP04561 0.50; 0.60; 0.74 ...  LDD0291 
ATP-dependent 6-phosphofructokinase, liver type (PFKL) LDTP02925 0.60  LDD0291 
ATP-dependent 6-phosphofructokinase, muscle type (PFKM) LDTP02261 1.12  LDD0291 
ATP-dependent RNA helicase A (DHX9) LDTP05550 0.32  LDD0291 
ATP-dependent RNA helicase DDX1 (DDX1) LDTP09766 0.33; 0.64  LDD0291 
ATP-dependent RNA helicase DHX15 (DHX15) LDTP00684 0.84  LDD0291 
ATPase MORC2 (MORC2) LDTP14308 0.99  LDD0291 
Aurora kinase B (AURKB) LDTP10346 0.55  LDD0291 
Bifunctional coenzyme A synthase (COASY) LDTP05736 0.67  LDD0291 
Bifunctional glutamate/proline--tRNA ligase (EPRS1) LDTP02222 0.60; 0.72  LDD0291 
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS) LDTP03159 1.32  LDD0291 
C-1-tetrahydrofolate synthase, cytoplasmic (MTHFD1) LDTP02580 0.53; 0.42; 1.06 ...  LDD0291 
Calcyclin-binding protein (CACYBP) LDTP12163 0.70; 0.51; 0.84  LDD0291 
Carbonyl reductase [NADPH] 1 (CBR1) LDTP02831 0.67  LDD0291 
Carbonyl reductase [NADPH] 3 (CBR3) LDTP01321 0.38  LDD0291 
Catalase (CAT) LDTP02001 1.27  LDD0291 
Cathepsin B (CTSB) LDTP02223 0.36; 0.41; 0.39 ...  LDD0291 
Cathepsin D (CTSD) LDTP02198 0.74; 0.92  LDD0291 
Cathepsin Z (CTSZ) LDTP13147 0.66; 1.19; 1.34 ...  LDD0291 
Citrate synthase, mitochondrial (CS) LDTP01205 0.63; 0.98; 0.49  LDD0291 
Cleavage and polyadenylation specificity factor subunit 5 (NUDT21) LDTP00873 1.03  LDD0291 
CTP synthase 1 (CTPS1) LDTP02922 0.20; 0.38; 0.67  LDD0291 
Cyclin-dependent kinase 1 (CDK1) LDTP02149 0.44; 0.49; 0.55 ...  LDD0291 
Cyclin-dependent kinase 2 (CDK2) LDTP03299 0.44; 0.55; 0.75  LDD0291 
Cystathionine gamma-lyase (CTH) LDTP03656 0.56  LDD0291 
Cytochrome c oxidase assembly factor 7 (COA7) LDTP10137 0.36  LDD0291 
Cytoglobin (CYGB) LDTP09656 0.92; 0.52  LDD0291 
Cytosol aminopeptidase (LAP3) LDTP03455 0.30  LDD0291 
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) LDTP00194 11.07; 0.76  LDD0291 
dCTP pyrophosphatase 1 (DCTPP1) LDTP12013 1.03  LDD0291 
Dehydrogenase/reductase SDR family member 11 (DHRS11) LDTP07678 0.17  LDD0291 
Dihydropteridine reductase (QDPR) LDTP02342 0.21  LDD0291 
Dihydropyrimidinase-related protein 3 (DPYSL3) LDTP06079 0.55  LDD0291 
Dipeptidyl peptidase 3 (DPP3) LDTP12803 0.45  LDD0291 
DNA repair nuclease/redox regulator APEX1 (APEX1) LDTP03398 1.00  LDD0291 
DNA replication licensing factor MCM2 (MCM2) LDTP04286 0.38  LDD0291 
DNA replication licensing factor MCM3 (MCM3) LDTP03316 4.38  LDD0291 
DNA replication licensing factor MCM4 (MCM4) LDTP03680 1.78  LDD0291 
DNA replication licensing factor MCM7 (MCM7) LDTP03682 1.55  LDD0291 
Dual specificity protein phosphatase 23 (DUSP23) LDTP11289 0.57  LDD0291 
Dual specificity protein phosphatase 3 (DUSP3) LDTP04415 0.88  LDD0291 
E3 ubiquitin-protein ligase ARIH2 (ARIH2) LDTP01575 0.59  LDD0291 
E3 ubiquitin-protein ligase NEDD4-like (NEDD4L) LDTP10699 0.93  LDD0291 
E3 ubiquitin-protein ligase UBR4 (UBR4) LDTP07118 0.43  LDD0291 
EH domain-containing protein 4 (EHD4) LDTP11788 0.37  LDD0291 
Elongation factor 1-alpha 1 (EEF1A1) LDTP05071 0.74; 0.32; 0.53 ...  LDD0291 
Elongation factor 2 (EEF2) LDTP02672 1.45; 0.39; 2.51 ...  LDD0291 
Elongation factor Tu, mitochondrial (TUFM) LDTP04251 0.85; 0.46; 0.58 ...  LDD0291 
Endoplasmic reticulum chaperone BiP (HSPA5) LDTP02534 9.46; 0.69; 0.76 ...  LDD0291 
Enoyl-CoA hydratase, mitochondrial (ECHS1) LDTP03518 0.48  LDD0291 
ERO1-like protein alpha (ERO1A) LDTP10386 3.76; 0.75  LDD0291 
Eukaryotic initiation factor 4A-I (EIF4A1) LDTP04878 0.64; 0.49; 0.51 ...  LDD0291 
Eukaryotic initiation factor 4A-III (EIF4A3) LDTP03861 0.51  LDD0291 
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) LDTP02770 1.33  LDD0291 
Exosome complex exonuclease RRP44 (DIS3) LDTP13887 0.59  LDD0291 
Farnesyl pyrophosphate synthase (FDPS) LDTP02721 0.61  LDD0291 
Fatty acid CoA ligase Acsl3 (ACSL3) LDTP01634 1.68; 0.42  LDD0291 
Fatty acid synthase (FASN) LDTP04243 0.78; 0.25; 0.69 ...  LDD0291 
Flap endonuclease 1 (FEN1) LDTP03872 0.44  LDD0291 
Fructose-2,6-bisphosphatase TIGAR (TIGAR) LDTP12405 0.64  LDD0291 
Fructose-bisphosphate aldolase A (ALDOA) LDTP02008 0.58; 0.92; 0.98 ...  LDD0291 
Fumarate hydratase, mitochondrial (FH) LDTP02235 0.70  LDD0291 
Fumarylacetoacetase (FAH) LDTP02868 0.43  LDD0291 
Galactokinase (GALK1) LDTP04424 0.40  LDD0291 
Gamma-enolase (ENO2) LDTP02328 1.21; 0.86  LDD0291 
GDP-mannose 4,6 dehydratase (GMDS) LDTP00999 0.58  LDD0291 
Geranylgeranyl transferase type-2 subunit beta (RABGGTB) LDTP04569 0.90  LDD0291 
Glucosamine-6-phosphate isomerase 1 (GNPDA1) LDTP04113 1.14  LDD0291 
Glucose-6-phosphate 1-dehydrogenase (G6PD) LDTP02569 0.66; 0.66  LDD0291 
Glucose-6-phosphate isomerase (GPI) LDTP02162 0.31; 0.59; 1.07  LDD0291 
Glutaminase kidney isoform, mitochondrial (GLS) LDTP01465 0.14  LDD0291 
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 (GFPT1) LDTP05481 0.76; 0.66  LDD0291 
Glutaredoxin-1 (GLRX) LDTP03786 0.97  LDD0291 
Glutathione S-transferase 3, mitochondrial (MGST3) LDTP00464 0.72; 0.14  LDD0291 
Glutathione S-transferase A4 (GSTA4) LDTP00575 16.61  LDD0291 
Glutathione S-transferase kappa 1 (GSTK1) LDTP13900 0.81  LDD0291 
Glutathione S-transferase omega-1 (GSTO1) LDTP05128 0.82  LDD0291 
Glutathione S-transferase P (GSTP1) LDTP02333 0.44; 0.69; 0.42 ...  LDD0291 
Glutathione synthetase (GSS) LDTP04200 0.44; 1.63  LDD0291 
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) LDTP02038 0.82; 0.48; 0.50 ...  LDD0291 
Glycine--tRNA ligase (GARS1) LDTP03946 0.61  LDD0291 
Glycogen phosphorylase, brain form (PYGB) LDTP02552 0.54; 0.41; 0.45 ...  LDD0291 
Glycogen synthase kinase-3 alpha (GSK3A) LDTP04318 0.61  LDD0291 
Glycogen synthase kinase-3 beta (GSK3B) LDTP04319 0.61  LDD0291 
GTP-binding nuclear protein Ran (RAN) LDTP05007 0.54; 0.68; 0.36 ...  LDD0291 
HBS1-like protein (HBS1L) LDTP14019 0.18  LDD0291 
Heat shock cognate 71 kDa protein (HSPA8) LDTP02541 0.86; 0.67; 0.72 ...  LDD0291 
Heat shock protein HSP 90-alpha (HSP90AA1) LDTP02225 0.66; 0.78; 0.80 ...  LDD0291 
Histone acetyltransferase type B catalytic subunit (HAT1) LDTP00479 0.39  LDD0291 
Histone deacetylase 1 (HDAC1) LDTP05918 0.36  LDD0291 
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) LDTP06645 0.41  LDD0291 
Hydroxymethylglutaryl-CoA lyase, mitochondrial (HMGCL) LDTP03794 0.82  LDD0291 
Inorganic pyrophosphatase (PPA1) LDTP14854 1.91; 0.66  LDD0291 
Inorganic pyrophosphatase 2, mitochondrial (PPA2) LDTP11842 0.67  LDD0291 
Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) LDTP02611 1.13; 0.71; 0.22 ...  LDD0291 
Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) LDTP11700 0.54  LDD0291 
Isocitrate dehydrogenase [NADP] cytoplasmic (IDH1) LDTP01333 0.38; 1.43; 0.34  LDD0291 
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (IDH3B) LDTP00885 0.36  LDD0291 
Isoleucine--tRNA ligase, cytoplasmic (IARS1) LDTP03947 0.31  LDD0291 
Kynurenine--oxoglutarate transaminase 3 (KYAT3) LDTP07763 0.27  LDD0291 
L-lactate dehydrogenase A chain (LDHA) LDTP01766 0.59; 1.04; 0.78 ...  LDD0291 
L-lactate dehydrogenase B chain (LDHB) LDTP02179 0.58; 0.69; 0.52 ...  LDD0291 
L-xylulose reductase (DCXR) LDTP08082 0.96  LDD0291 
Lactoylglutathione lyase (GLO1) LDTP05434 1.01  LDD0291 
Low molecular weight phosphotyrosine protein phosphatase (ACP1) LDTP03289 0.54; 0.54  LDD0291 
Lymphokine-activated killer T-cell-originated protein kinase (PBK) LDTP10500 0.92; 0.95  LDD0291 
Lysosomal protective protein (CTSA) LDTP02505 1.21  LDD0291 
Macrophage migration inhibitory factor (MIF) LDTP02713 0.41; 1.98; 0.41 ...  LDD0291 
Malate dehydrogenase, cytoplasmic (MDH1) LDTP03907 0.66; 0.80  LDD0291 
Malate dehydrogenase, mitochondrial (MDH2) LDTP03908 0.71; 0.64; 0.95  LDD0291 
Mannose-1-phosphate guanyltransferase beta (GMPPB) LDTP14141 0.33  LDD0291 
MAP kinase-activated protein kinase 3 (MAPKAPK3) LDTP06589 0.07; 1.01  LDD0291 
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADM) LDTP02565 0.65; 1.08; 0.17 ...  LDD0291 
Methionine adenosyltransferase 2 subunit beta (MAT2B) LDTP12915 0.75  LDD0291 
Methionine--tRNA ligase, cytoplasmic (MARS1) LDTP04730 0.65  LDD0291 
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (MCCC2) LDTP12227 1.87  LDD0291 
Methylthioribulose-1-phosphate dehydratase (APIP) LDTP10368 0.24  LDD0291 
Mitochondrial-processing peptidase subunit beta (PMPCB) LDTP01220 7.00  LDD0291 
Mitogen-activated protein kinase 1 (MAPK1) LDTP03445 1.14; 0.40  LDD0291 
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (PLOD3) LDTP01005 0.41; 0.34  LDD0291 
Myosin-10 (MYH10) LDTP03765 0.44; 1.04; 0.59 ...  LDD0291 
Myosin-9 (MYH9) LDTP03764 0.58; 1.30; 0.38 ...  LDD0291 
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (NTMT1) LDTP11273 0.64  LDD0291 
NAD(P)H dehydrogenase [quinone] 1 (NQO1) LDTP02798 0.83; 1.03  LDD0291 
NEDD8-activating enzyme E1 catalytic subunit (UBA3) LDTP09338 0.58  LDD0291 
NEDD8-activating enzyme E1 regulatory subunit (NAE1) LDTP05925 1.19  LDD0291 
NEDD8-conjugating enzyme Ubc12 (UBE2M) LDTP04898 0.64  LDD0291 
Neutral alpha-glucosidase AB (GANAB) LDTP06192 0.89; 0.95  LDD0291 
Nucleoside diphosphate kinase B (NME2) LDTP03169 1.06  LDD0291 
Omega-amidase NIT2 (NIT2) LDTP12428 0.73; 0.53; 0.52 ...  LDD0291 
Palmitoyl-protein thioesterase ABHD10, mitochondrial (ABHD10) LDTP12628 11.46; 1.25  LDD0291 
Palmitoyltransferase ZDHHC17 (ZDHHC17) LDTP08456 0.96  LDD0291 
Peptidyl-prolyl cis-trans isomerase A (PPIA) LDTP05028 1.91; 1.01  LDD0291 
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) LDTP10101 0.93  LDD0291 
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) LDTP05029 0.40  LDD0291 
Peptidyl-prolyl cis-trans isomerase FKBP4 (FKBP4) LDTP05372 1.19; 1.67; 0.36  LDD0291 
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) LDTP05912 0.80  LDD0291 
Peptidyl-prolyl cis-trans isomerase-like 3 (PPIL3) LDTP11823 1.03  LDD0291 
Peroxiredoxin-1 (PRDX1) LDTP05503 1.25; 0.83; 1.17  LDD0291 
Peroxiredoxin-4 (PRDX4) LDTP05773 0.81; 0.33  LDD0291 
Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) LDTP06307 0.21  LDD0291 
Phosphatidylinositide phosphatase SAC2 (INPP5F) LDTP13867 0.30  LDD0291 
Phosphoglucomutase-1 (PGM1) LDTP03818 1.25  LDD0291 
Phosphoglycerate kinase 1 (PGK1) LDTP01787 1.19; 0.88; 1.25 ...  LDD0291 
Phosphoglycerate mutase 1 (PGAM1) LDTP02963 0.59; 2.15; 0.83 ...  LDD0291 
Phosphoserine aminotransferase (PSAT1) LDTP14198 0.40; 0.48; 0.81 ...  LDD0291 
Poly(A) polymerase alpha (PAPOLA) LDTP04394 0.44  LDD0291 
Probable 18S rRNA (guanine-N(7))-methyltransferase (BUD23) LDTP00845 1.67  LDD0291 
Probable aminopeptidase NPEPL1 (NPEPL1) LDTP09126 0.88  LDD0291 
Probable E3 ubiquitin-protein ligase IRF2BPL (IRF2BPL) LDTP11759 0.44; 0.49  LDD0291 
Prolyl endopeptidase (PREP) LDTP04163 0.31  LDD0291 
Prostaglandin reductase 1 (PTGR1) LDTP06227 0.34; 0.48  LDD0291 
Prostaglandin reductase 2 (PTGR2) LDTP08979 2.32; 4.45; 20.00  LDD0291 
Proteasome subunit alpha type-1 (PSMA1) LDTP03330 0.54; 0.84  LDD0291 
Proteasome subunit alpha type-2 (PSMA2) LDTP03331 0.50; 0.49; 0.67  LDD0291 
Proteasome subunit alpha type-3 (PSMA3) LDTP03332 0.46  LDD0291 
Proteasome subunit alpha type-6 (PSMA6) LDTP04884 0.46; 0.38; 0.83 ...  LDD0291 
Proteasome subunit alpha type-7 (PSMA7) LDTP00449 0.38; 0.53; 0.46 ...  LDD0291 
Proteasome subunit beta type-1 (PSMB1) LDTP03060 3.56; 4.08  LDD0291 
Proteasome subunit beta type-2 (PSMB2) LDTP04285 0.42  LDD0291 
Proteasome subunit beta type-5 (PSMB5) LDTP03419 0.64; 0.34  LDD0291 
Proteasome subunit beta type-6 (PSMB6) LDTP03418 0.68; 0.38  LDD0291 
Protein disulfide-isomerase (P4HB) LDTP02188 2.01; 0.75; 0.89 ...  LDD0291 
Protein disulfide-isomerase A3 (PDIA3) LDTP03521 0.80; 0.86; 1.19 ...  LDD0291 
Protein disulfide-isomerase A4 (PDIA4) LDTP02677 1.69; 1.49; 2.08  LDD0291 
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) LDTP04246 0.59  LDD0291 
Protein kinase C delta type (PRKCD) LDTP05461 0.62  LDD0291 
Protein phosphatase 1G (PPM1G) LDTP00616 15.49  LDD0291 
Puromycin-sensitive aminopeptidase (NPEPPS) LDTP04712 0.15  LDD0291 
Putative elongation factor 1-alpha-like 3 (EEF1A1P5) LDTP15029 0.74; 0.32; 0.53 ...  LDD0291 
Pyridoxine-5'-phosphate oxidase (PNPO) LDTP12691 0.61  LDD0291 
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) LDTP02279 0.64; 0.36  LDD0291 
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) LDTP02549 1.10; 1.43; 1.03 ...  LDD0291 
Pyruvate kinase PKM (PKM) LDTP02733 0.23; 0.83; 0.67 ...  LDD0291 
Queuine tRNA-ribosyltransferase catalytic subunit 1 (QTRT1) LDTP11400 0.77  LDD0291 
RAC-beta serine/threonine-protein kinase (AKT2) LDTP03608 1.03; 0.32  LDD0291 
RAC-gamma serine/threonine-protein kinase (AKT3) LDTP13799 0.30; 0.32  LDD0291 
Ras GTPase-activating protein-binding protein 1 (G3BP1) LDTP05812 0.33  LDD0291 
Ras-related C3 botulinum toxin substrate 1 (RAC1) LDTP05037 0.64; 0.47  LDD0291 
Ribonucleoside-diphosphate reductase large subunit (RRM1) LDTP03259 1.03  LDD0291 
RING finger and CHY zinc finger domain-containing protein 1 (RCHY1) LDTP10686 0.47  LDD0291 
RNA demethylase ALKBH5 (ALKBH5) LDTP07547 0.69  LDD0291 
RuvB-like 1 (RUVBL1) LDTP13816 0.38  LDD0291 
S-adenosylmethionine synthase isoform type-2 (MAT2A) LDTP03577 0.31; 0.24  LDD0291 
S-formylglutathione hydrolase (ESD) LDTP02521 0.85; 0.84  LDD0291 
S-methyl-5'-thioadenosine phosphorylase (MTAP) LDTP05758 0.14  LDD0291 
Saccharopine dehydrogenase-like oxidoreductase (SCCPDH) LDTP15484 0.69  LDD0291 
Sepiapterin reductase (SPR) LDTP03730 0.96; 0.45  LDD0291 
Septin-2 (SEPTIN2) LDTP06279 0.63  LDD0291 
Septin-7 (SEPTIN7) LDTP06513 0.40; 0.50  LDD0291 
Septin-9 (SEPTIN9) LDTP13272 0.49; 0.66; 0.75  LDD0291 
Serine hydroxymethyltransferase, cytosolic (SHMT1) LDTP03688 0.43  LDD0291 
Serine hydroxymethyltransferase, mitochondrial (SHMT2) LDTP03689 1.27  LDD0291 
Serine/threonine-protein kinase PAK 2 (PAK2) LDTP05776 0.62  LDD0291 
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PPP2R1A) LDTP03522 0.65  LDD0291 
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA) LDTP05064 0.47; 0.63  LDD0291 
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PPP2CB) LDTP04998 0.47  LDD0291 
Serine/threonine-protein phosphatase 4 catalytic subunit (PPP4C) LDTP04870 0.47  LDD0291 
Serine/threonine-protein phosphatase 5 (PPP5C) LDTP04554 0.99  LDD0291 
Serine/threonine-protein phosphatase 6 catalytic subunit (PPP6C) LDTP00333 1.27  LDD0291 
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PPP1CA) LDTP04959 0.38; 0.43  LDD0291 
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) LDTP04960 0.38; 0.43  LDD0291 
Sialic acid synthase (NANS) LDTP12473 0.32; 0.34; 0.52  LDD0291 
Spermidine synthase (SRM) LDTP03008 0.06  LDD0291 
Spliceosome RNA helicase DDX39B (DDX39B) LDTP05991 0.67  LDD0291 
Staphylococcal nuclease domain-containing protein 1 (SND1) LDTP07929 0.46; 0.52  LDD0291 
Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (SMCHD1) LDTP00101 1.18  LDD0291 
SUMO-activating enzyme subunit 1 (SAE1) LDTP13107 0.62  LDD0291 
SUMO-activating enzyme subunit 2 (UBA2) LDTP13156 0.37; 0.46  LDD0291 
Synaptic vesicle membrane protein VAT-1 homolog (VAT1) LDTP10887 0.79; 0.80  LDD0291 
Thimet oligopeptidase (THOP1) LDTP04542 0.30  LDD0291 
Thioredoxin domain-containing protein 12 (TXNDC12) LDTP01707 0.59  LDD0291 
Thioredoxin domain-containing protein 5 (TXNDC5) LDTP09067 0.74; 0.53; 0.42 ...  LDD0291 
Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) LDTP03515 0.15  LDD0291 
Threonine--tRNA ligase 1, cytoplasmic (TARS1) LDTP03365 0.90; 0.67; 0.33 ...  LDD0291 
Thymidylate kinase (DTYMK) LDTP03258 0.27  LDD0291 
Transcription intermediary factor 1-beta (TRIM28) LDTP05808 0.36; 0.57; 0.59 ...  LDD0291 
Transitional endoplasmic reticulum ATPase (VCP) LDTP04665 0.95  LDD0291 
Transketolase (TKT) LDTP03487 0.28; 0.32; 0.64 ...  LDD0291 
Trifunctional purine biosynthetic protein adenosine-3 (GART) LDTP03156 0.71  LDD0291 
Triosephosphate isomerase (TPI1) LDTP04851 0.59; 7.42; 0.42  LDD0291 
Tripeptidyl-peptidase 1 (TPP1) LDTP00428 1.29  LDD0291 
Tryptophan--tRNA ligase, cytoplasmic (WARS1) LDTP03222 0.54; 0.20; 0.19 ...  LDD0291 
Tubulin alpha-1A chain (TUBA1A) LDTP07907 0.39; 0.39; 0.37 ...  LDD0291 
Tubulin alpha-1B chain (TUBA1B) LDTP05074 0.39; 0.39; 0.37 ...  LDD0291 
Tubulin alpha-1C chain (TUBA1C) LDTP11074 0.41  LDD0291 
Tubulin--tyrosine ligase-like protein 12 (TTLL12) LDTP06067 0.53; 0.05  LDD0291 
Tyrosine--tRNA ligase, cytoplasmic (YARS1) LDTP04617 0.67; 0.89  LDD0291 
Tyrosine-protein kinase CSK (CSK) LDTP03944 0.38  LDD0291 
U5 small nuclear ribonucleoprotein 200 kDa helicase (SNRNP200) LDTP01283 1.65  LDD0291 
Ubiquitin carboxyl-terminal hydrolase 14 (USP14) LDTP04618 0.26  LDD0291 
Ubiquitin carboxyl-terminal hydrolase 39 (USP39) LDTP06903 0.85  LDD0291 
Ubiquitin carboxyl-terminal hydrolase 4 (USP4) LDTP05749 1.20  LDD0291 
Ubiquitin-conjugating enzyme E2 N (UBE2N) LDTP04900 0.89; 1.64; 1.15  LDD0291 
Ubiquitin-like modifier-activating enzyme 1 (UBA1) LDTP03166 0.86; 0.25; 0.43 ...  LDD0291 
UDP-glucose 4-epimerase (GALE) LDTP06111 1.23  LDD0291 
UDP-glucose 6-dehydrogenase (UGDH) LDTP01033 0.56; 0.29; 0.47 ...  LDD0291 
UMP-CMP kinase (CMPK1) LDTP03519 0.73  LDD0291 
Uridine 5'-monophosphate synthase (UMPS) LDTP02548 0.38  LDD0291 
Uridine phosphorylase 1 (UPP1) LDTP06643 0.93; 1.29; 0.55 ...  LDD0291 
Uroporphyrinogen decarboxylase (UROD) LDTP02135 1.23; 0.36  LDD0291 
V-type proton ATPase catalytic subunit A (ATP6V1A) LDTP03859 1.30; 0.61; 0.67  LDD0291 
V-type proton ATPase subunit E 2 (ATP6V1E2) LDTP15684 0.76  LDD0291 
Valine--tRNA ligase (VARS1) LDTP03366 1.17  LDD0291 
WD repeat-containing protein 82 (WDR82) LDTP07715 0.51  LDD0291 
Xaa-Pro aminopeptidase 1 (XPNPEP1) LDTP12444 0.90; 1.02  LDD0291 
------------------------------------------------------------------------------------
⏷ Show the Full List of 290 Enzyme
40 Transporter and channel Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
14-3-3 protein epsilon (YWHAE) LDTP04969 1.04; 0.38; 0.34 ...  LDD0291 
14-3-3 protein gamma (YWHAG) LDTP04953 1.13  LDD0291 
14-3-3 protein theta (YWHAQ) LDTP03385 1.19  LDD0291 
14-3-3 protein zeta/delta (YWHAZ) LDTP05043 0.63; 0.50; 1.23 ...  LDD0291 
Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) LDTP01601 0.50; 0.51  LDD0291 
Alpha-synuclein (SNCA) LDTP03848 1.67  LDD0291 
Annexin A2 (ANXA2) LDTP02199 0.72; 1.10; 0.44 ...  LDD0291 
Annexin A5 (ANXA5) LDTP02307 0.70; 0.57; 0.66 ...  LDD0291 
Annexin A6 (ANXA6) LDTP02247 0.47  LDD0291 
AP-1 complex subunit gamma-1 (AP1G1) LDTP00855 0.49  LDD0291 
ATP synthase subunit alpha, mitochondrial (ATP5F1A) LDTP03327 0.74  LDD0291 
Calreticulin (CALR) LDTP03402 0.57; 0.83; 1.05 ...  LDD0291 
Cation-independent mannose-6-phosphate receptor (IGF2R) LDTP02586 1.75  LDD0291 
Chloride intracellular channel protein 1 (CLIC1) LDTP00244 1.12; 0.51; 0.51 ...  LDD0291 
Chloride intracellular channel protein 4 (CLIC4) LDTP14222 0.98; 0.79; 0.78 ...  LDD0291 
Clathrin heavy chain 1 (CLTC) LDTP05252 0.54; 0.90  LDD0291 
Copine-3 (CPNE3) LDTP01133 0.59; 0.94  LDD0291 
Cystatin-B (CSTB) LDTP02009 0.67; 0.54; 0.65  LDD0291 
Dihydropyrimidinase-related protein 2 (DPYSL2) LDTP06554 2.81; 0.55; 0.53 ...  LDD0291 
Eukaryotic translation initiation factor 5A-1 (EIF5A) LDTP05056 0.87; 0.66  LDD0291 
Exportin-1 (XPO1) LDTP00501 0.30; 0.90  LDD0291 
Exportin-2 (CSE1L) LDTP04662 0.37  LDD0291 
Filamin-A (FLNA) LDTP03107 0.93; 0.91  LDD0291 
Galectin-3 (LGALS3) LDTP02929 0.65  LDD0291 
Heat shock protein HSP 90-beta (HSP90AB1) LDTP02262 0.54; 0.52; 1.43 ...  LDD0291 
Hsp90 co-chaperone Cdc37 (CDC37) LDTP06549 0.48  LDD0291 
Importin subunit beta-1 (KPNB1) LDTP06242 0.49  LDD0291 
mRNA export factor RAE1 (RAE1) LDTP05122 0.48  LDD0291 
Small ribosomal subunit protein RACK1 (RACK1) LDTP05057 0.47; 0.23  LDD0291 
T-complex protein 1 subunit delta (CCT4) LDTP04391 0.64; 0.49; 0.91 ...  LDD0291 
Talin-1 (TLN1) LDTP14031 0.88; 0.66; 0.53 ...  LDD0291 
Thioredoxin domain-containing protein 17 (TXNDC17) LDTP11103 0.53; 0.65; 0.55  LDD0291 
Transferrin receptor protein 1 (TFRC) LDTP01969 1.21  LDD0291 
Ubiquilin-4 (UBQLN4) LDTP12533 0.54  LDD0291 
V-type proton ATPase subunit B, brain isoform (ATP6V1B2) LDTP03104 0.62  LDD0291 
V-type proton ATPase subunit C 1 (ATP6V1C1) LDTP03105 0.80  LDD0291 
V-type proton ATPase subunit E 1 (ATP6V1E1) LDTP03811 0.76  LDD0291 
V-type proton ATPase subunit G 1 (ATP6V1G1) LDTP01185 0.73  LDD0291 
Vacuolar protein sorting-associated protein 35 (VPS35) LDTP10741 0.45  LDD0291 
Voltage-gated potassium channel subunit beta-2 (KCNAB2) LDTP05817 0.86  LDD0291 
------------------------------------------------------------------------------------
⏷ Show the Full List of 40 Transporter and channel
8 Transcription factor Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
High mobility group protein B1 (HMGB1) LDTP02343 1.20; 0.90; 0.98 ...  LDD0291 
Metastasis-associated protein MTA2 (MTA2) LDTP01414 0.24  LDD0291 
Nascent polypeptide-associated complex subunit alpha, muscle-specific form (NACA) LDTP14411 0.09  LDD0291 
Signal transducer and activator of transcription 3 (STAT3) LDTP03903 4.42  LDD0291 
Signal transducer and activator of transcription 5A (STAT5A) LDTP03971 0.64  LDD0291 
Transcription factor SOX-10 (SOX10) LDTP04752 1.20; 0.35  LDD0291 
Transcription factor SOX-9 (SOX9) LDTP04179 0.97  LDD0291 
Y-box-binding protein 1 (YBX1) LDTP05065 0.89; 1.11; 1.46  LDD0291 
------------------------------------------------------------------------------------
⏷ Show the Full List of 8 Transcription factor
272 Other Competed by This Competitor
Target Name Target ID Binding Ratio Interaction ID
10 kDa heat shock protein, mitochondrial (HSPE1) LDTP04931 3.32  LDD0291 
14-3-3 protein beta/alpha (YWHAB) LDTP03617 0.37; 0.36  LDD0291 
14-3-3 protein eta (YWHAH) LDTP05442 0.61  LDD0291 
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) LDTP00223 0.53  LDD0291 
55 kDa erythrocyte membrane protein (MPP1) LDTP05233 0.88  LDD0291 
Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) LDTP03871 0.56  LDD0291 
Acidic leucine-rich nuclear phosphoprotein 32 family member B (ANP32B) LDTP09843 0.49  LDD0291 
Actin nucleation-promoting factor WASL (WASL) LDTP00263 0.88  LDD0291 
Actin-related protein 3 (ACTR3) LDTP04902 0.53; 0.45; 0.28 ...  LDD0291 
Adapter molecule crk (CRK) LDTP04091 0.61; 0.51; 1.03  LDD0291 
Adenylyl cyclase-associated protein 1 (CAP1) LDTP05294 0.25; 0.49; 0.93  LDD0291 
AH receptor-interacting protein (AIP) LDTP00202 0.62  LDD0291 
Alpha-actinin-1 (ACTN1) LDTP02631 0.87; 0.59; 1.35  LDD0291 
Alpha-centractin (ACTR1A) LDTP04904 0.21  LDD0291 
Anamorsin (CIAPIN1) LDTP07385 0.34  LDD0291 
Ankyrin repeat and MYND domain-containing protein 2 (ANKMY2) LDTP17620 0.78  LDD0291 
Ankyrin repeat domain-containing protein 39 (ANKRD39) LDTP19320 0.34  LDD0291 
Annexin A3 (ANXA3) LDTP02620 1.24  LDD0291 
Annexin A7 (ANXA7) LDTP03030 0.55  LDD0291 
Apoptosis inhibitor 5 (API5) LDTP11575 0.67  LDD0291 
Beta-parvin (PARVB) LDTP12184 1.81  LDD0291 
Bifunctional purine biosynthesis protein ATIC (ATIC) LDTP03612 0.82; 0.41; 0.48 ...  LDD0291 
C-Jun-amino-terminal kinase-interacting protein 4 (SPAG9) LDTP00934 0.59; 0.46  LDD0291 
Calpain small subunit 1 (CAPNS1) LDTP02047 0.63  LDD0291 
Calponin-3 (CNN3) LDTP06383 0.63; 0.39; 0.55 ...  LDD0291 
Calumenin (CALU) LDTP00887 0.44; 0.46; 0.61 ...  LDD0291 
cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A) LDTP02697 1.65  LDD0291 
CCHC-type zinc finger nucleic acid binding protein (CNBP) LDTP04995 0.66; 0.72; 1.01 ...  LDD0291 
Cell cycle and apoptosis regulator protein 2 (CCAR2) LDTP08760 1.46  LDD0291 
Coatomer subunit beta (COPB1) LDTP04570 0.54  LDD0291 
Coatomer subunit gamma-1 (COPG1) LDTP14216 0.57  LDD0291 
Cofilin-1 (CFL1) LDTP03244 0.92; 0.95; 0.86 ...  LDD0291 
Cold shock domain-containing protein E1 (CSDE1) LDTP01252 1.07  LDD0291 
Condensin complex subunit 2 (NCAPH) LDTP06268 0.56  LDD0291 
Copper transport protein ATOX1 (ATOX1) LDTP00229 0.97  LDD0291 
Coronin-1B (CORO1B) LDTP11101 0.91  LDD0291 
Coronin-1C (CORO1C) LDTP13580 0.61  LDD0291 
Crk-like protein (CRKL) LDTP04092 0.88; 1.46; 0.38  LDD0291 
Cysteine and glycine-rich protein 1 (CSRP1) LDTP03106 0.95; 0.50; 0.86  LDD0291 
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) LDTP06083 0.55; 0.81; 0.92 ...  LDD0291 
Cytoplasmic FMR1-interacting protein 1 (CYFIP1) LDTP07958 0.65  LDD0291 
Cytotoxic granule associated RNA binding protein TIA1 (TIA1) LDTP03598 0.43  LDD0291 
Destrin (DSTN) LDTP04887 0.18; 1.10  LDD0291 
DnaJ homolog subfamily A member 2 (DNAJA2) LDTP01073 1.31  LDD0291 
DnaJ homolog subfamily B member 1 (DNAJB1) LDTP03325 0.57  LDD0291 
DnaJ homolog subfamily C member 3 (DNAJC3) LDTP05789 1.32  LDD0291 
DnaJ homolog subfamily C member 8 (DNAJC8) LDTP01361 1.30  LDD0291 
Drebrin-like protein (DBNL) LDTP13399 0.66; 0.37; 0.95  LDD0291 
Dynactin subunit 1 (DCTN1) LDTP06082 0.93  LDD0291 
Dynactin subunit 2 (DCTN2) LDTP05922 0.73  LDD0291 
Dynein light chain 1, cytoplasmic (DYNLL1) LDTP05049 0.85  LDD0291 
Dynein light chain 2, cytoplasmic (DYNLL2) LDTP10308 0.82  LDD0291 
ELAV-like protein 1 (ELAVL1) LDTP06450 0.16  LDD0291 
Elongation factor 1-beta (EEF1B2) LDTP03283 0.60; 0.73; 0.77 ...  LDD0291 
Elongation factor 1-delta (EEF1D) LDTP03499 0.50; 0.80; 0.55  LDD0291 
Elongation factor 1-gamma (EEF1G) LDTP03367 0.39; 0.63; 0.93  LDD0291 
Endoplasmic reticulum resident protein 29 (ERP29) LDTP03509 0.55; 0.80  LDD0291 
Endoplasmin (HSP90B1) LDTP02734 0.54; 0.95; 0.75 ...  LDD0291 
Enhancer of mRNA-decapping protein 3 (EDC3) LDTP10299 0.58  LDD0291 
Epidermal growth factor receptor substrate 15-like 1 (EPS15L1) LDTP13097 0.54  LDD0291 
Eukaryotic translation initiation factor 1 (EIF1) LDTP03953 0.65  LDD0291 
Eukaryotic translation initiation factor 1A, X-chromosomal (EIF1AX) LDTP04129 0.76  LDD0291 
Eukaryotic translation initiation factor 1b (EIF1B) LDTP16815 0.65  LDD0291 
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) LDTP02101 0.39  LDD0291 
Eukaryotic translation initiation factor 3 subunit A (EIF3A) LDTP06055 1.13  LDD0291 
Eukaryotic translation initiation factor 3 subunit C (EIF3C) LDTP10919 0.36  LDD0291 
Eukaryotic translation initiation factor 3 subunit G (EIF3G) LDTP01319 1.28  LDD0291 
Eukaryotic translation initiation factor 3 subunit I (EIF3I) LDTP05834 0.41  LDD0291 
Eukaryotic translation initiation factor 3 subunit L (EIF3L) LDTP13813 0.34; 1.21  LDD0291 
Eukaryotic translation initiation factor 4B (EIF4B) LDTP03247 1.04  LDD0291 
F-actin-uncapping protein LRRC16A (CARMIL1) LDTP07261 0.39  LDD0291 
Far upstream element-binding protein 1 (FUBP1) LDTP10078 1.00; 1.09; 1.08  LDD0291 
Far upstream element-binding protein 2 (KHSRP) LDTP09938 0.64; 0.62; 0.44 ...  LDD0291 
Gelsolin (GSN) LDTP02145 1.60; 0.53; 0.53 ...  LDD0291 
General transcription factor IIF subunit 2 (GTF2F2) LDTP02703 0.50; 0.50  LDD0291 
General vesicular transport factor p115 (USO1) LDTP01048 0.65  LDD0291 
Growth factor receptor-bound protein 2 (GRB2) LDTP05035 1.04  LDD0291 
GTPase-activating protein and VPS9 domain-containing protein 1 (GAPVD1) LDTP06255 0.90  LDD0291 
Heat shock 70 kDa protein 1A (HSPA1A) LDTP02434 0.86; 0.85; 0.95 ...  LDD0291 
Heat shock 70 kDa protein 4 (HSPA4) LDTP03695 0.35; 0.54; 0.58 ...  LDD0291 
Heat shock 70 kDa protein 4L (HSPA4L) LDTP14545 0.85  LDD0291 
Heat shock protein 105 kDa (HSPH1) LDTP09811 1.57; 0.49  LDD0291 
Heat shock protein 75 kDa, mitochondrial (TRAP1) LDTP05697 1.15  LDD0291 
Heat shock protein beta-1 (HSPB1) LDTP02053 0.63; 0.55; 0.45 ...  LDD0291 
Heme-binding protein 1 (HEBP1) LDTP16078 0.71; 0.38  LDD0291 
Hepatoma-derived growth factor (HDGF) LDTP04483 0.07  LDD0291 
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) LDTP10962 0.48; 0.45  LDD0291 
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) LDTP02364 0.72; 0.52; 0.50 ...  LDD0291 
Heterogeneous nuclear ribonucleoprotein A3 (HNRNPA3) LDTP04495 0.34; 0.38; 0.40  LDD0291 
Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) LDTP06032 0.61  LDD0291 
Heterogeneous nuclear ribonucleoprotein F (HNRNPF) LDTP04514 0.99; 0.33; 0.53 ...  LDD0291 
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) LDTP03615 0.59; 0.54; 0.38 ...  LDD0291 
Heterogeneous nuclear ribonucleoprotein K (HNRNPK) LDTP04952 0.44; 1.71; 0.36 ...  LDD0291 
Heterogeneous nuclear ribonucleoprotein M (HNRNPM) LDTP04500 0.80  LDD0291 
Heterogeneous nuclear ribonucleoprotein Q (SYNCRIP) LDTP00991 1.29  LDD0291 
Heterogeneous nuclear ribonucleoprotein R (HNRNPR) LDTP00756 0.30; 0.31; 0.33 ...  LDD0291 
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) LDTP05259 0.79; 0.60; 0.53 ...  LDD0291 
Heterogeneous nuclear ribonucleoprotein U-like protein 2 (HNRNPUL2) LDTP17065 0.14  LDD0291 
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) LDTP03182 0.73; 0.41; 0.36 ...  LDD0291 
Histone H2B type 1-D (H2BC5) LDTP04822 0.55; 0.37; 1.54  LDD0291 
Histone H2B type 1-L (H2BC13) LDTP11001 1.54  LDD0291 
Histone H4 (H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16) LDTP05004 3.04; 0.46  LDD0291 
Histone-binding protein RBBP7 (RBBP7) LDTP06562 1.04; 0.78  LDD0291 
Hsc70-interacting protein (ST13) LDTP04367 1.28; 0.96; 0.93  LDD0291 
Influenza virus NS1A-binding protein (IVNS1ABP) LDTP14309 0.42  LDD0291 
Integrator complex subunit 10 (INTS10) LDTP16111 0.64  LDD0291 
IST1 homolog (IST1) LDTP04593 0.59  LDD0291 
Kinesin light chain 1 (KLC1) LDTP05533 0.47; 0.50  LDD0291 
Kinesin light chain 2 (KLC2) LDTP11695 0.47; 0.50  LDD0291 
Laminin subunit beta-2 (LAMB2) LDTP04691 1.24  LDD0291 
Large ribosomal subunit protein eL20 (RPL18A) LDTP05360 0.67  LDD0291 
Large ribosomal subunit protein eL21 (RPL21) LDTP04107 0.44; 0.28; 0.44  LDD0291 
Large ribosomal subunit protein eL24 (RPL24) LDTP05186 0.46; 0.55  LDD0291 
Large ribosomal subunit protein eL28 (RPL28) LDTP04108 0.44; 5.31  LDD0291 
Large ribosomal subunit protein eL29 (RPL29) LDTP04140 0.52  LDD0291 
Large ribosomal subunit protein eL31 (RPL31) LDTP05023 1.63  LDD0291 
Large ribosomal subunit protein eL32 (RPL32) LDTP05025 0.37  LDD0291 
Large ribosomal subunit protein eL33 (RPL35A) LDTP02940 0.45  LDD0291 
Large ribosomal subunit protein eL34 (RPL34) LDTP04233 0.34  LDD0291 
Large ribosomal subunit protein eL37 (RPL37) LDTP04943 0.48  LDD0291 
Large ribosomal subunit protein eL6 (RPL6) LDTP05378 0.36  LDD0291 
Large ribosomal subunit protein uL13 (RPL13A) LDTP03899 0.43; 0.44  LDD0291 
Large ribosomal subunit protein uL14 (RPL23) LDTP05008 0.81  LDD0291 
Large ribosomal subunit protein uL16 (RPL10) LDTP03395 0.22  LDD0291 
Large ribosomal subunit protein uL18 (RPL5) LDTP04106 0.76  LDD0291 
Large ribosomal subunit protein uL2 (RPL8) LDTP05027 0.43  LDD0291 
Large ribosomal subunit protein uL29 (RPL35) LDTP03999 0.28  LDD0291 
Large ribosomal subunit protein uL30 (RPL7) LDTP02944 0.32  LDD0291 
Large ribosomal subunit protein uL4 (RPL4) LDTP03815 0.16; 0.25  LDD0291 
LIM and SH3 domain protein 1 (LASP1) LDTP06220 0.81; 0.94  LDD0291 
LIM domain and actin-binding protein 1 (LIMA1) LDTP13260 1.38; 0.86  LDD0291 
LRP chaperone MESD (MESD) LDTP06191 0.44  LDD0291 
Macrophage-capping protein (CAPG) LDTP03877 7.19; 2.82  LDD0291 
Microtubule-associated protein 4 (MAP4) LDTP03404 0.66  LDD0291 
Mitotic checkpoint protein BUB3 (BUB3) LDTP00838 0.40  LDD0291 
Muscleblind-like protein 1 (MBNL1) LDTP12478 0.55  LDD0291 
Muscleblind-like protein 2 (MBNL2) LDTP07260 0.55  LDD0291 
Myeloid-derived growth factor (MYDGF) LDTP10003 2.15  LDD0291 
Myosin light polypeptide 6 (MYL6) LDTP04875 0.43  LDD0291 
Myosin regulatory light chain 12B (MYL12B) LDTP00487 0.08; 0.60  LDD0291 
N6-adenosine-methyltransferase non-catalytic subunit (METTL14) LDTP12234 0.50  LDD0291 
Nascent polypeptide-associated complex subunit alpha (NACA) LDTP05977 0.09  LDD0291 
Nuclear autoantigenic sperm protein (NASP) LDTP04241 0.48; 0.31  LDD0291 
Nuclear migration protein nudC (NUDC) LDTP13817 0.39  LDD0291 
Nucleolin (NCL) LDTP02990 1.18; 0.47; 0.48 ...  LDD0291 
Nucleolysin TIAR (TIAL1) LDTP05274 1.14  LDD0291 
Nucleophosmin (NPM1) LDTP02164 0.72; 0.69; 0.59  LDD0291 
Nucleosome assembly protein 1-like 1 (NAP1L1) LDTP04684 0.41; 1.34; 0.47  LDD0291 
Nucleosome assembly protein 1-like 4 (NAP1L4) LDTP10965 0.50; 0.47  LDD0291 
Oxysterol-binding protein-related protein 11 (OSBPL11) LDTP11367 1.40  LDD0291 
Perilipin-3 (PLIN3) LDTP01021 0.47  LDD0291 
Phosphatidylethanolamine-binding protein 1 (PEBP1) LDTP03520 0.40; 1.29; 0.92 ...  LDD0291 
Plastin-3 (PLS3) LDTP02692 3.76; 0.29  LDD0291 
Platelet-activating factor acetylhydrolase IB subunit beta (PAFAH1B1) LDTP04015 1.01; 0.82  LDD0291 
Poly(rC)-binding protein 1 (PCBP1) LDTP06366 0.83; 0.37; 0.64  LDD0291 
Poly(rC)-binding protein 2 (PCBP2) LDTP06367 0.42; 0.90  LDD0291 
Polyadenylate-binding protein 1 (PABPC1) LDTP02595 1.06; 0.40; 0.63 ...  LDD0291 
Polyadenylate-binding protein 4 (PABPC4) LDTP05821 0.65; 0.25  LDD0291 
Polypyrimidine tract-binding protein 1 (PTBP1) LDTP03364 0.71; 1.28  LDD0291 
Prefoldin subunit 3 (VBP1) LDTP04935 1.00  LDD0291 
Prefoldin subunit 6 (PFDN6) LDTP00573 0.37  LDD0291 
Prelamin-A/C (LMNA) LDTP01932 1.04; 0.66  LDD0291 
Profilin-1 (PFN1) LDTP02218 0.59; 0.83  LDD0291 
Programmed cell death protein 5 (PDCD5) LDTP00417 1.01; 1.65  LDD0291 
Proliferating cell nuclear antigen (PCNA) LDTP02596 0.63; 0.69  LDD0291 
Protein BUD31 homolog (BUD31) LDTP03935 0.20  LDD0291 
Protein FAM118B (FAM118B) LDTP15852 4.25  LDD0291 
Protein flightless-1 homolog (FLII) LDTP05734 0.38  LDD0291 
Protein kinase C and casein kinase substrate in neurons protein 2 (PACSIN2) LDTP13656 0.62; 0.83; 1.12 ...  LDD0291 
Protein mago nashi homolog 2 (MAGOHB) LDTP10071 0.81  LDD0291 
Protein NipSnap homolog 3A (NIPSNAP3A) LDTP18525 2.94; 11.66  LDD0291 
Protein phosphatase 1 regulatory subunit 12A (PPP1R12A) LDTP00495 1.54  LDD0291 
Protein RCC2 (RCC2) LDTP13020 0.62  LDD0291 
Protein S100-A11 (S100A11) LDTP03620 1.11; 1.16  LDD0291 
Protein SET (SET) LDTP05277 1.21  LDD0291 
Protein SGT1 homolog (SUGT1) LDTP13935 0.75; 0.48  LDD0291 
Protein TFG (TFG) LDTP09851 0.83  LDD0291 
Protein transport protein Sec23A (SEC23A) LDTP06390 0.11; 0.38  LDD0291 
Protein transport protein Sec23B (SEC23B) LDTP06391 0.43  LDD0291 
Protein UXT (UXT) LDTP13125 0.19  LDD0291 
Putative protein FAM10A5 (ST13P5) LDTP17811 0.93  LDD0291 
Putative RNA-binding protein Luc7-like 2 (LUC7L2) LDTP13956 0.57  LDD0291 
Pyridoxal phosphate homeostasis protein (PLPBP) LDTP14521 0.29; 0.60  LDD0291 
Rab GDP dissociation inhibitor alpha (GDI1) LDTP03574 0.93; 0.86  LDD0291 
Rab GDP dissociation inhibitor beta (GDI2) LDTP04355 0.84; 0.80; 0.16 ...  LDD0291 
Ran-specific GTPase-activating protein (RANBP1) LDTP04049 0.78  LDD0291 
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) LDTP04117 0.61; 0.39; 0.05 ...  LDD0291 
Reticulocalbin-1 (RCN1) LDTP06352 1.28  LDD0291 
Retinoblastoma-associated protein (RB1) LDTP02146 0.33  LDD0291 
Rho GDP-dissociation inhibitor 1 (ARHGDIA) LDTP04510 0.53; 1.16; 1.20 ...  LDD0291 
Rho guanine nucleotide exchange factor 2 (ARHGEF2) LDTP09950 0.19  LDD0291 
Ribosome biogenesis protein WDR12 (WDR12) LDTP11625 1.28  LDD0291 
RNA-binding protein 3 (RBM3) LDTP05226 0.28; 0.32  LDD0291 
RNA-binding protein EWS (EWSR1) LDTP05318 0.22  LDD0291 
RNA-binding protein FUS (FUS) LDTP03775 2.49; 0.74  LDD0291 
Serine/arginine-rich splicing factor 2 (SRSF2) LDTP05280 0.36  LDD0291 
Serine/arginine-rich splicing factor 8 (SRSF8) LDTP11117 0.36  LDD0291 
Serpin H1 (SERPINH1) LDTP04363 0.57  LDD0291 
Single-stranded DNA-binding protein, mitochondrial (SSBP1) LDTP05437 0.82; 1.10; 0.73 ...  LDD0291 
Small acidic protein (SMAP) LDTP19007 0.55  LDD0291 
Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA) LDTP00862 0.47; 0.57; 0.65  LDD0291 
Small ribosomal subunit protein eS1 (RPS3A) LDTP04913 0.49; 0.29; 0.43  LDD0291 
Small ribosomal subunit protein eS12 (RPS12) LDTP03321 0.53; 0.29  LDD0291 
Small ribosomal subunit protein eS19 (RPS19) LDTP03864 0.19  LDD0291 
Small ribosomal subunit protein eS24 (RPS24) LDTP05012 0.59; 0.50; 0.39  LDD0291 
Small ribosomal subunit protein eS26 (RPS26) LDTP05014 0.27  LDD0291 
Small ribosomal subunit protein eS4, X isoform (RPS4X) LDTP04997 0.45; 0.48  LDD0291 
Small ribosomal subunit protein eS4, Y isoform 1 (RPS4Y1) LDTP14653 0.48  LDD0291 
Small ribosomal subunit protein eS4, Y isoform 2 (RPS4Y2) LDTP19820 0.48  LDD0291 
Small ribosomal subunit protein eS7 (RPS7) LDTP04958 0.43  LDD0291 
Small ribosomal subunit protein eS8 (RPS8) LDTP04964 0.77; 0.71; 1.08 ...  LDD0291 
Small ribosomal subunit protein uS11 (RPS14) LDTP04970 0.32  LDD0291 
Small ribosomal subunit protein uS12 (RPS23) LDTP04971 0.16  LDD0291 
Small ribosomal subunit protein uS13 (RPS18) LDTP04972 0.32; 1.05; 0.65  LDD0291 
Small ribosomal subunit protein uS15 (RPS13) LDTP04974 0.44; 0.59; 0.58  LDD0291 
Small ribosomal subunit protein uS17 (RPS11) LDTP04975 0.38; 0.71  LDD0291 
Small ribosomal subunit protein uS2 (RPSA) LDTP02312 0.21  LDD0291 
Small ribosomal subunit protein uS5 (RPS2) LDTP02809 0.39; 0.71; 0.41  LDD0291 
Small ribosomal subunit protein uS7 (RPS5) LDTP04110 0.30; 0.56  LDD0291 
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) LDTP05985 1.08; 0.68  LDD0291 
Splicing factor 3B subunit 3 (SF3B3) LDTP06376 0.19  LDD0291 
Src substrate cortactin (CTTN) LDTP06094 0.60; 0.71; 0.62 ...  LDD0291 
Stress-70 protein, mitochondrial (HSPA9) LDTP03860 1.08; 0.59; 0.35 ...  LDD0291 
Stress-induced-phosphoprotein 1 (STIP1) LDTP03619 0.46; 0.15; 0.36 ...  LDD0291 
Stromal cell-derived factor 2-like protein 1 (SDF2L1) LDTP16047 1.47  LDD0291 
Structural maintenance of chromosomes protein 1A (SMC1A) LDTP06181 0.44; 1.00  LDD0291 
Structural maintenance of chromosomes protein 2 (SMC2) LDTP01567 0.96  LDD0291 
Structural maintenance of chromosomes protein 4 (SMC4) LDTP12606 0.30  LDD0291 
T-complex protein 1 subunit beta (CCT2) LDTP05113 0.71; 0.39  LDD0291 
T-complex protein 1 subunit epsilon (CCT5) LDTP04201 0.78  LDD0291 
T-complex protein 1 subunit eta (CCT7) LDTP10990 0.69  LDD0291 
T-complex protein 1 subunit gamma (CCT3) LDTP04249 0.46; 0.53  LDD0291 
T-complex protein 1 subunit theta (CCT8) LDTP04390 0.71; 0.44; 0.55 ...  LDD0291 
T-complex protein 1 subunit zeta (CCT6A) LDTP03888 0.30  LDD0291 
T-complex protein 1 subunit zeta-2 (CCT6B) LDTP09777 0.30  LDD0291 
Tetratricopeptide repeat protein 1 (TTC1) LDTP15840 1.15  LDD0291 
Tetratricopeptide repeat protein 4 (TTC4) LDTP01678 0.35  LDD0291 
Transcription elongation factor A protein 1 (TCEA1) LDTP03209 0.61  LDD0291 
Transcription elongation factor SPT6 (SUPT6H) LDTP07928 0.11  LDD0291 
Transgelin-2 (TAGLN2) LDTP03846 0.76; 0.75; 0.66  LDD0291 
Translation initiation factor eIF2B subunit delta (EIF2B4) LDTP13318 1.73  LDD0291 
Translationally-controlled tumor protein (TPT1) LDTP02683 0.45; 0.62  LDD0291 
Transmembrane glycoprotein NMB (GPNMB) LDTP06237 1.07  LDD0291 
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WDR6) LDTP12296 0.29  LDD0291 
Tropomyosin alpha-3 chain (TPM3) LDTP02165 0.79  LDD0291 
Tropomyosin alpha-4 chain (TPM4) LDTP05068 0.82  LDD0291 
Tubulin beta chain (TUBB) LDTP02205 0.38; 0.56; 0.69 ...  LDD0291 
Tubulin beta-2A chain (TUBB2A) LDTP05998 0.09; 0.46; 0.44 ...  LDD0291 
Tubulin beta-2B chain (TUBB2B) LDTP11277 0.61; 0.46; 0.44 ...  LDD0291 
Tubulin beta-3 chain (TUBB3) LDTP05904 0.38; 0.44; 0.40 ...  LDD0291 
Tubulin beta-4A chain (TUBB4A) LDTP02037 0.34; 0.36; 0.46 ...  LDD0291 
Tubulin beta-4B chain (TUBB4B) LDTP05076 0.95; 0.43; 0.42 ...  LDD0291 
Tubulin beta-6 chain (TUBB6) LDTP11233 0.60; 0.41; 0.08 ...  LDD0291 
Tubulin gamma-1 chain (TUBG1) LDTP03213 0.45  LDD0291 
Tubulin gamma-2 chain (TUBG2) LDTP12512 0.45  LDD0291 
Tubulin-folding cofactor B (TBCB) LDTP10860 0.77; 0.68  LDD0291 
U6 snRNA-associated Sm-like protein LSm2 (LSM2) LDTP13946 1.25  LDD0291 
Ubiquilin-1 (UBQLN1) LDTP13626 0.56  LDD0291 
Ubiquitin-associated protein 2-like (UBAP2L) LDTP06060 3.46; 0.32  LDD0291 
Ubiquitin-fold modifier 1 (UFM1) LDTP04946 0.98  LDD0291 
UV excision repair protein RAD23 homolog A (RAD23A) LDTP04626 0.98  LDD0291 
Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) LDTP11534 0.95  LDD0291 
Vacuolar fusion protein CCZ1 homolog (CCZ1) LDTP14797 1.02  LDD0291 
Vasodilator-stimulated phosphoprotein (VASP) LDTP04372 0.87  LDD0291 
Vimentin (VIM) LDTP02297 1.05; 0.61; 0.40 ...  LDD0291 
Vinculin (VCL) LDTP02946 0.79; 1.09  LDD0291 
WD repeat and HMG-box DNA-binding protein 1 (WDHD1) LDTP01299 0.47  LDD0291 
WD repeat-containing protein 1 (WDR1) LDTP01118 1.14; 1.05; 1.76 ...  LDD0291 
WD repeat-containing protein 5 (WDR5) LDTP04948 0.58  LDD0291 
WW domain-binding protein 2 (WBP2) LDTP10033 1.28; 1.36; 0.43 ...  LDD0291 
Zinc finger CCHC domain-containing protein 8 (ZCCHC8) LDTP07496 0.07  LDD0291 
Zyxin (ZYX) LDTP06507 0.91; 0.85  LDD0291 
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Full Information of The Labelling Profiles of This Competitor

HHS-482
 Probe Info 
Quantification: Probe vs (Probe+Competitor)
  
Experiment 1 Reporting the Labelling Profiles of This Probe
REF [1]
Probe concentration 50 uM
Quantitative Method SILAC
Competitor Name JWB202
Competitor Concentration 50 uM
In Vitro Experiment Model Model Type
Cell lysate
Derived Tissue
Skin
Disease Model Melanoma [ICD-11:2C82]
Model Name Human melanoma cell lysate (DM93)
Interaction Atlas ID  LDD0291  Download The Altas

References

1 Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes. Chem Sci. 2021 Jan 21;12(9):3295-3307. doi: 10.1039/d0sc06623k.